Protective bottle sleeve for preventing mannitol from crystallizing in winter

By designing a protective bottle cover including a heat source chamber, a bottle insulation cover and a heat transfer plate, the problem of mannitol crystallization in a low-temperature environment is solved, effectively preventing crystallization in hospitals and outdoor first aid, and ensuring the stability of drug infusion.

CN120022459AInactive Publication Date: 2025-05-23BEIJING ANZHEN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510420480.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-04
Publication Date
2025-05-23
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Mannitol is prone to crystallization in low temperature environments or at high concentrations, affecting drug infusion and product stability. The existing methods to prevent crystallization are not effective during out-of-hospital emergency treatment.

Method used

A protective bottle cover is designed to prevent mannitol crystallization in winter, including a heat source chamber, a bottle insulation cover and a heat transfer plate. Heat is generated by filling the reaction in the heat source chamber. The heat transfer plate conducts heat to the bottle body, keeping paraffin in a constant temperature state, and preventing mannitol crystallization.

Benefits of technology

This protective bottle cover can be used in hospitals and outdoor first aid. It can be reused multiple times, has low cost, can effectively prevent mannitol crystallization and ensure the stability of drug infusion.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120022459A_ABST
    Figure CN120022459A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of medical auxiliary materials, in particular to a protective bottle sleeve for preventing mannitol crystallization in winter, which comprises a heat source chamber, the heat source chamber comprises a protective sleeve for placing reaction filling and a fixing cover detachably connected with the protective sleeve, a water bag is adhered in a cavity of the fixing cover, a needle head is arranged at the axis of the protective sleeve, and the needle head is connected with the water bag. The pressing plate slides on the needling head, so that the tip end of the needling head is exposed; the bottle heat preservation sleeve is detachably connected with the heat source chamber, the inner diameter of the bottle heat preservation sleeve is matched with the size of a mannitol bottle, and a bottle neck binding part is arranged at the bottom of the bottle heat preservation sleeve. The thermal insulation sleeve has the effect that the thermal insulation sleeve can be used in hospitals and outdoor first aid, and is provided with a rapid heating part, when the thermal insulation sleeve is used for out-of-hospital first aid, after bottling, water is in contact with the reaction filler, generated heat can be rapidly conducted to the position of the built-in metal plate, then paraffin is melted, and after the paraffin is melted, the thermal insulation sleeve is convenient to use. And long-time constant-temperature conditions can be kept, and the device is convenient to use and can be used at any time.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the technical field of medical auxiliary materials, and in particular to a protective bottle cover for preventing mannitol from crystallizing in winter. Background Art

[0002] Mannitol is commonly used in clinical practice to reduce intracranial pressure, reduce intraocular pressure, and promote renal excretion. Mannitol is prone to crystallization during use and storage, especially in low temperature environments or at high concentrations. Crystallization may affect drug infusion, product stability, and other aspects.

[0003] The commonly used method is to store it in a high-temperature box. In clinical use, there are two ways to protect mannitol from crystallization. The first is to heat the infusion tube, but the heating temperature of the plastic tube is difficult to control. The other is external heating. In the later stage of use, crystallization will occur again. Especially in the process of emergency treatment outside the hospital, there is no good way to prevent crystallization. Summary of the invention

[0004] The purpose of the invention is to provide a protective bottle cover for preventing mannitol from crystallizing in winter, which has the advantages of being disassembled and used immediately, being applicable to outdoor first aid and hospital use, being repeatedly used and having low cost.

[0005] To achieve the above object, the present invention provides the following technical solution: a protective bottle cover for preventing mannitol from crystallizing in winter, comprising:

[0006] The heat source chamber comprises a protective sleeve for placing the reaction filling, and a fixed cover detachably connected to the protective sleeve, a water bag is glued to the fixed cover chamber, an acupuncture head is arranged at the axis of the protective sleeve, and a pressing plate slides on the acupuncture head so that the tip of the acupuncture head is exposed;

[0007] A bottle insulation cover, wherein the bottle insulation cover is detachably connected to the heat source chamber, and the inner diameter of the bottle insulation cover is adapted to the size of the mannitol bottle, and a bottleneck restraining part is arranged at the bottom of the bottle insulation cover, and the bottleneck restraining part includes two types of long specifications and segment specifications, and is mainly made of soft silica gel or elastic textile material, and is used to wrap the neck of the mannitol bottle body, and the main function is that the bottleneck restraining part can be manually opened, and the mannitol bottle body can be quickly replaced;

[0008] The heat transfer plate is fixedly connected to the inner cavity of the heat source chamber, and the insertion part extends downward from the heat source chamber and is bent and expanded outward, and the bottle insulation cover is suspended at the reverse hook set on the insertion part.

[0009] Furthermore, the fixing cover includes an annular fixing part and a middle circular part, the annular fixing part and the middle circular part are connected by annular silicone, the water bag is adhered to the middle circular part, the bottom of the annular fixing part is fixedly connected with an outer ring panel, and the bottom of the middle circular part is fixedly connected with an inner panel.

[0010] Furthermore, an inner chamber for placing reaction filling is provided in the protective sleeve, the inner chamber is supported by metal material, the inner wall of the inner chamber is fixedly connected to the heat-bearing plate, and the inner chamber at the bottom of the protective sleeve is fixedly connected to the insulation plate.

[0011] Furthermore, an isolation cavity is provided at the top of the protective sleeve, and the isolation cavity is vacuum-set. A pressure ring is provided in the isolation cavity, and a plurality of embedded beads are embedded at the top of the pressure ring.

[0012] Furthermore, the heat transfer plate is provided at one end of the heat source chamber with an arc plate in contact with the outer wall of the inner chamber, and a conduction bar is provided outside the arc plate, and the conduction bar and the arc plate are integrally formed to form the heat transfer plate.

[0013] Furthermore, the heat transfer plate comprises one or two of quicklime, magnesium powder, iron powder, salt and bentonite or diatomaceous earth.

[0014] Furthermore, a honeycomb thermal insulation sleeve is provided on the outside of the heating sleeve, and the inner layer is a thermal insulation layer. Regarding the heating sleeve, the honeycomb thermal insulation sleeve is used to block the internal heat while allowing the conducted heat to quickly disappear on the surface. During the process of medical staff holding the sleeve, the heat felt is below the safe temperature, and during the holding process, the medical staff may wear protective gloves, which have low friction. The honeycomb structure of the honeycomb thermal insulation sleeve increases safety during the holding process. Regarding the thermal insulation layer, it can be a common thermal insulation material, such as foam cotton.

[0015] Furthermore, the bottle sticker part includes a heat-insulating part, a heat-collecting sleeve is arranged on the inner side of the heat-insulating part, a built-in metal plate is arranged in the heat-collecting sleeve, and evenly distributed hole chambers are arranged in the built-in metal plate, and the hole chambers are filled with paraffin. An insertion port is arranged at the heat-collecting sleeve, and the insertion part is inserted into the insertion port. Regarding the bottle sticker part, the bottle sticker part is suspended on the reverse hook by a hook rope. During use, the heat source chamber and the heating sleeve remain separated, that is, a single one is replaceable, or a separate heating sleeve can be used separately, and it can be hung on the water hanging rack by a hook rope. The specific use is as follows.

[0016] Furthermore, the heating sleeve is provided with a hook rope, and the hook rope is hung on the reverse hook.

[0017] Technical effects and advantages of the present invention:

[0018] 1. The insulation cover can be used both in hospitals and in outdoor first aid, and is equipped with a fast heating part. When used for emergency treatment outside the hospital, after the bottle is filled, the water can be in contact with the reaction filling, and the heat generated can be quickly transferred to the position of the built-in metal plate to melt the paraffin. After the paraffin is melted, it can maintain a constant temperature for a long time. It is convenient to use and can be used whenever you want.

[0019] 2. The bottleneck restraining part includes two types: long and segment specifications, which are mainly made of soft silicone or elastic textile material and are used to wrap the neck of the mannitol bottle. Its main function is to manually open the bottleneck restraining part so that the mannitol bottle can be replaced quickly.

[0020] 3. The honeycomb thermal insulation sleeve is used to block the internal heat while making the conducted heat disappear quickly on the surface. When the medical staff holds the device, the heat they feel is below the safe temperature. In addition, the medical staff may wear protective gloves with low friction during the holding process. The honeycomb structure of the honeycomb thermal insulation sleeve increases safety during the holding process. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 A three-dimensional diagram of a long bottleneck restraining portion of the present invention;

[0022] Figure 2 A three-dimensional diagram of a short bottleneck restraining portion of the present invention;

[0023] Figure 3 is a cross-sectional view of the heat source chamber of the present invention;

[0024] Figure 4 For the present invention Figure 3 Enlarged view of point A in the middle;

[0025] Figure 5 is a cross-sectional view of the present invention;

[0026] Figure 6 A cross-sectional view of the device with an insertion port according to the present invention;

[0027] Figure 7 It is a schematic diagram of the built-in metal plate in the present invention.

[0028] In the figure:

[0029] 1. Heat source chamber; 11. Fixed cover; 12. Water bag; 13. Protective cover; 14. Reaction filling; 15. Acupuncture head; 16. Pressing plate; 17. Heat bearing plate; 18. Inner chamber; 19. Pressing ring; 110. Embedded beads; 111. Outer ring inlay plate; 112. Inner inlay plate; 2. Heating sleeve; 3. Bottle neck restraint part; 4. Heat transfer plate; 41. Insertion part; 42. Reverse hook; 5. Insulation plate; 6. Bottle sticking part; 61. Insulation part; 62. Heat collecting sleeve; 63. Insertion port; 64. Built-in metal plate; 65. Hole chamber; 66. Paraffin; 7. Hook rope. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Reference Figures 1 to 7 A protective bottle cover for preventing mannitol from crystallizing in winter, comprising:

[0032] The heat source chamber 1 includes a protective sleeve 13 for placing a reaction filler 14, and a fixed cover 11 detachably connected to the protective sleeve 13, a water bag 12 is glued to the chamber of the fixed cover 11, an acupuncture head 15 is arranged at the axis of the protective sleeve 13, and a pressing plate 16 slides on the acupuncture head 15, so that the tip of the acupuncture head 15 is exposed;

[0033] The bottle insulation cover is detachably connected to the heat source chamber 1, and the inner diameter of the bottle insulation cover is adapted to the size of the mannitol bottle, and a bottleneck restraining part 3 is provided at the bottom of the bottle insulation cover;

[0034] The heat transfer plate 4 is fixedly connected to the inner cavity of the heat source chamber 1, and the insertion part 41 extends downward from the heat source chamber 1 and is bent and expanded outward, and the bottle insulation cover is hung at the reverse hook 42 set on the insertion part 41.

[0035] The fixing cover 11 includes an annular fixing part and a middle circular part, the annular fixing part and the middle circular part are connected by an annular silicone, the water bag 12 is glued to the middle circular part, the bottom of the annular fixing part is fixedly connected with an outer ring panel 111, and the bottom of the middle circular part is fixedly connected with an inner panel 112.

[0036] An inner chamber 18 for placing the reaction filling 14 is provided in the protective sleeve 13 . The inner chamber 18 is supported by metal material. The inner wall of the inner chamber 18 is fixedly connected to the heat bearing plate 17 . The inner chamber at the bottom of the protective sleeve 13 is fixedly connected to the insulation plate 5 .

[0037] An isolation cavity is also provided on the top of the protective sleeve 13 . The isolation cavity is a vacuum cavity. A pressure ring 19 is provided in the isolation cavity. A plurality of embedded beads 110 are embedded on the top of the pressure ring 19 .

[0038] The heat transfer plate 4 is located at one end of the heat source chamber 1 and is provided with an arc-shaped plate in contact with the outer wall of the inner chamber 18, and a conduction strip is provided outside the arc-shaped plate. The conduction strip and the arc-shaped plate are integrally formed to form the heat transfer plate 4.

[0039] The heat transfer plate 4 is filled with one or two of quicklime, magnesium powder, iron powder, salt and bentonite or diatomaceous earth.

[0040] The outside of the heating jacket 2 is provided with a honeycomb-shaped heat-insulating jacket, and the inner layer is a heat-insulating layer.

[0041] The bottle label part 6 includes a heat-insulating part 61, a heat-collecting sleeve 62 is arranged on the inner side of the heat-insulating part 61, a built-in metal plate 64 is arranged in the heat-collecting sleeve 62, and evenly distributed holes 65 are arranged on the built-in metal plate 64. The holes 65 are filled with paraffin 66. An insertion port 63 is arranged at the heat-collecting sleeve 62, and the insertion part 41 is inserted into the insertion port 63.

[0042] In fact, the pore chamber 65 and the paraffin 66 in the pore chamber 65 are arranged in the form of microcapsules, which occupy a small space, are light in weight after solidification, and are convenient for heat to be concentrated at various positions of the bottle body and heated evenly.

[0043] The heating sleeve 2 is provided with a hook rope 7, and the hook rope 7 is hung on the reverse hook 42. When used outdoors, it is only necessary to hang the hook rope 7 on the reverse hook 42.

[0044] The bottleneck binding part 3 includes two types of long specifications and segment specifications, and is mainly made of soft silicone or elastic textile material, and is used to wrap the neck of the mannitol bottle body. The main function is that the bottleneck binding part 3 can be manually opened, and the mannitol bottle body can be quickly replaced;

[0045] Regarding the heating sleeve 2, the honeycomb insulation sleeve is used to block the internal heat while making the conducted heat disappear quickly on the surface. When the medical staff holds the sleeve, the heat they feel is below the safe temperature. In the process of holding the sleeve, the medical staff may wear protective gloves, which have low friction. The honeycomb structure of the honeycomb insulation sleeve increases the safety during the holding process. Regarding the insulation layer, it can be a common insulation material, such as foam cotton.

[0046] Regarding the bottle sticker part 6, the bottle sticker part 6 is hung on the reverse hook 42 through the hook rope 7. During use, the heat source chamber 1 and the heating sleeve 2 remain separated, that is, a single one can be replaced, or a separate heating sleeve 2 can be used separately. At this time, it can be hung on the water hanging rack through the hook rope 7. The specific use is as follows:

[0047] Scenario 1: When used in a hospital, due to the perfect basic configuration of the hospital, the heating sleeve 2 can be directly placed on the heating device for ten minutes to ensure that the temperature is below 60 degrees Celsius. In this way, the internal built-in metal plate 64 obtains the temperature, so that the internal built-in metal plate 64 in the internal hole chamber 65 melts into a transparent liquid, and passive constant temperature is achieved through the fixed phase change point of paraffin such as 42°C. It is important to note that a low-melting point wax sheet with a melting point of 45°C is added between the paraffin layer and the outer layer. When the temperature is too high, the wax sheet melts and absorbs heat to prevent the drug solution from overheating, and then the mannitol bottle is put inside.

[0048] Scenario 2: When used in an emergency scenario, by configuring the heat source chamber 1, in the practical process, mannitol can be placed in the bottle sticker part 6 first, and then the hook rope 7 is hung on the reverse hook 42, and then the reaction filler 14 is placed on the heat-bearing plate 17 in the inner chamber 18. It should be noted that a hole is reserved in the center of the reaction filler 14 for the acupuncture head 15 to pass through. After the reaction filler 14 is placed, the reaction filler 14 is pressed by the pressing plate 16, and then the pressing plate 16 is rotated to fix it on the acupuncture head 15, and then the water bag 12 is attached to the fixing cover 11, and then fixed on the protective cover 13. When in use, the fixing cover 11 can be pressed so that after the water bag 12 is punctured, water enters the surface of the reaction filler 14 from the hole of the pressing plate 16. It should be noted that there are sieve holes on the pressing plate 16, so that after quicklime, magnesium powder, iron powder, and salt come into contact with water, CaO+H 2 O→Ca(OH) 2 + heat; Mg+2H 2 O→Mg(OH) 2 +H 2 + heat; Fe+H 2 O+O 2 →Fe 2 O 3 +H 2 + heat; it should be noted that calcium oxide is the main heat-generating substance, iron powder enhances the heat release of the reaction; carbon powder is sometimes used to stabilize the temperature; salt promotes the electrolytic reaction and improves the heat release efficiency; bentonite or diatomaceous earth is used as a filler to prevent the reaction from being too fast).

[0049] In addition, the fixed cover 11 is provided with an external exhaust hole for releasing the internal pressure and gas. The gas is collected by the built-in cotton ball. After the heat is generated, it is transferred to the position of the bottle sticker part 6 through the heat transfer plate 4. It should be noted that the bottle sticker part 6 has multiple parts, which are equidistantly distributed at the position of the built-in metal plate 64. The heat transfer plate 4 is preferably a copper sheet with a fast heat conduction speed, so that the heat can be quickly transferred to the position of the built-in metal plate 64. Since the heat generated by the above scheme can reach a higher temperature, a part of the heat loss is guaranteed, so that the temperature transferred to the bottle body is about 50 degrees, so that the paraffin melts, and then maintains a temperature of about 45 degrees. Together with the heat loss and the heat loss in the infusion, the temperature entering the human body is about 26 degrees. The heat source chamber 1 is isolated from the bottle body by the insulation board 5, and the insulation board 5 is provided with a vacuum cavity to avoid excessive heat transfer.

[0050] Paraffin 66 phase change materials (PCM) absorb / release latent heat during the solid-liquid phase change. By precisely selecting the carbon chain length of the paraffin (which determines the phase change temperature), constant temperature control can be achieved within the target temperature range (e.g. 37-45°C).

[0051] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A protective bottle cover for preventing mannitol from crystallizing in winter, characterized in that: include: A heat source chamber (1), the heat source chamber (1) comprising a protective sleeve (13) for placing a reaction filler (14), and a fixed cover (11) detachably connected to the protective sleeve (13), a water bag (12) being adhered to a chamber of the fixed cover (11), a needle puncture head (15) being arranged at the axis of the protective sleeve (13), and a pressing plate (16) sliding on the needle puncture head (15) so that the tip of the needle puncture head (15) is exposed; A bottle insulation cover, the bottle insulation cover is detachably connected to the heat source chamber (1), the inner diameter of the bottle insulation cover is adapted to the size of the mannitol bottle, and a bottleneck restraining portion (3) is provided at the bottom of the bottle insulation cover; A heat transfer plate (4), the heat transfer plate (4) is fixedly connected to the inner cavity of the heat source chamber (1), and an insertion portion (41) extends downward from the heat source chamber (1) and is bent and expanded outward, and the bottle insulation sleeve is suspended at a reverse hook (42) provided on the insertion portion (41).

2. A protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The fixing cover (11) comprises an annular fixing part and a middle circular part, the annular fixing part and the middle circular part are connected via an annular silicone, the water bag (12) is adhered to the middle circular part, the bottom of the annular fixing part is fixedly connected to an outer ring panel (111), and the bottom of the middle circular part is fixedly connected to an inner panel (112).

3. A protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The protective sleeve (13) is provided with an inner chamber (18) for placing the reaction filling (14); the inner chamber (18) is supported by a metal material; the inner wall of the inner chamber (18) is fixedly connected to a heat-bearing plate (17); and the inner chamber at the bottom of the protective sleeve (13) is fixedly connected to an insulating plate (5).

4. A protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: An isolation chamber is also provided at the top of the protective sleeve (13), and the isolation chamber is vacuum-set. A pressure ring (19) is provided in the isolation chamber, and a plurality of embedded beads (110) are embedded at the top of the pressure ring (19).

5. The protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The heat transfer plate (4) is located at one end of the heat source chamber (1), and is provided with an arc-shaped plate that fits the outer wall of the inner chamber (18), and a conduction strip arranged on the outer side of the arc-shaped plate, and the conduction strip and the arc-shaped plate are integrally formed to form the heat transfer plate (4).

6. The protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The heat transfer plate (4) is filled with quicklime, magnesium powder, iron powder, salt and one or two of bentonite or diatomaceous earth.

7. The protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The heating sleeve (2) is provided with a honeycomb-shaped heat-insulating sleeve on the outside, and the inner layer is a heat-insulating layer.

8. The protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The bottle label part (6) comprises a heat-insulating part (61), a heat-collecting sleeve (62) is arranged on the inner side of the heat-insulating part (61), a built-in metal plate (64) is arranged in the heat-collecting sleeve (62), evenly distributed pores (65) are arranged on the built-in metal plate (64), the pores (65) are filled with paraffin (66), an insertion port (63) is arranged at the heat-collecting sleeve (62), and the insertion part (41) is inserted into the insertion port (63).

9. The protective bottle cover for preventing mannitol from crystallizing in winter according to claim 1, characterized in that: The heating sleeve (2) is provided with a hook rope (7), and the hook rope (7) is hung on the reverse hook (42).