Fresh water product drug residue detection device and detection method thereof

Abstract

The invention belongs to the technical field of medicine detection, and particularly discloses a fresh water product medicine residue detection device which comprises a mixing assembly, a lifting assembly, a filtering assembly, a storage assembly, a detection assembly and a supporting assembly. The lifting assembly is arranged on the side edge of the mixing assembly, the supporting assembly is arranged below the mixing assembly, the filtering assembly and the storage assembly are arranged on the inner side of the supporting assembly, the filtering assembly is located above the storage assembly, and the detection assembly is arranged on the side edge of the supporting assembly; the mixing assembly is used for stirring and mixing an aquatic product sample and an extraction solvent to output a mixed solution; the lifting assembly is used for adjusting the stirring depth in the mixing assembly; the filtering assembly is used for filtering the mixed solution to output an extracting solution; the storage component is used for storing an extracting solution; the detection module is used for detecting the concentration of the residual medicine in the extracting solution; the supporting assembly is used for supporting the filtering assembly and the storage assembly.

Description

Technical Field

[0001] The invention relates to the technical field of drug detection, in particular to a device for detecting drug residues in freshwater products and a detection method thereof. Background Art

[0002] Aquatic animal diseases are characterized by a wide variety of types, a wide coverage, and irregular onset times, and the problem of drug residues is becoming increasingly prominent.

[0003] At present, the drug residue detection device in aquatic products usually uses a mixing device to mix the crushed aquatic product sample and the extraction solvent to output the mixed liquid, and uses a screen to filter the mixed liquid to separate the extract from the matrix, and then uses the extract to detect drug residues. However, most of the various devices in the drug residue detection in aquatic products are installed separately, and each step requires manual transfer operation, which is very cumbersome and greatly increases the workload of workers. Summary of the invention

[0004] The purpose of the present invention is to provide a device and method for detecting drug residues in freshwater products to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solution: a device for detecting drug residues in freshwater products, comprising a mixing component, a lifting component, a filtering component, a storage component, a detection component and a supporting component.

[0006] The lifting assembly is arranged on the side of the mixing assembly, the supporting assembly is arranged below the mixing assembly, the filtering assembly and the storage assembly are arranged on the inner side of the supporting assembly, the filtering assembly is located above the storage assembly, and the detecting assembly is arranged on the side of the supporting assembly.

[0007] The mixing component is used to stir and mix the aquatic product sample and the extraction solvent to output a mixed liquid; the lifting component is used to adjust the stirring depth inside the mixing component; the filtering component is used to filter the mixed liquid to output an extracted liquid; the storage component is used to store the extracted liquid; the detection module is used to detect the concentration of residual drugs in the extracted liquid; and the supporting component is used to support the filtering component and the storage component.

[0008] Preferably, the mixing assembly includes a tank body, a rotating rod, a stirring blade and a scraper; the rotating rod is located inside the tank body, the top end of the rotating rod passes through the tank body, the stirring blade is fixed on the rotating rod, the scraper is fixed at the end of the rotating rod, and the scraper is in contact with the inner wall of the tank body.

[0009] The aquatic product sample and the extraction solvent are stirred and mixed by driving the stirring blades through the rotating rod, and the scraper can prevent the sample from adhering to the inner wall of the tank.

[0010] Preferably, the tank body is provided with a first feeding port and a second feeding port, a discharge port is provided below the tank body, a valve is provided on the discharge port, and an observation window is provided on the front of the tank body.

[0011] The first feeding port is used for adding aquatic product samples, the second feeding port is used for adding extraction solvents, and the discharge port is used for discharging the mixed liquid.

[0012] Preferably, the lifting assembly includes a slide rail, a screw rod, a first drive motor, a slider, a connecting plate and a second drive motor; the slide rail is fixed on the tank body, the screw rod and the slider are arranged on the inner side of the slide rail, the screw rod passes through the slider, the screw rod and the slide rail are connected by a rotation, the slider and the screw rod are connected by a threaded connection, the first drive motor is fixed on the top of the slide rail, the drive shaft of the first drive motor is connected to the screw rod, the connecting plate is L-shaped and fixed on the slider, the second drive motor is fixed on the connecting plate, and the drive shaft of the second drive motor is connected to the rotating rod.

[0013] The second drive motor drives the rotating rod to rotate to cooperate with the stirring blade to stir and mix, the first drive motor drives the screw rod to rotate, and the screw rod drives the slider to move, so that the slider drives the rotating rod to move up and down through the connecting plate, thereby adjusting the stirring depth.

[0014] Preferably, the filter assembly includes a filter box and a pull-out frame inserted inside the filter box, a filter screen is provided at the bottom of the pull-out frame, the filter box is connected to the discharge port, the mixed liquid is discharged into the filter box through the discharge port, the mixed liquid is filtered by the filter screen on the pull-out frame, the extract is filtered out, and the matrix remains in the filter screen.

[0015] Preferably, the filter box has a screw hole on the side, a locking bolt is threadedly connected to the screw hole, and the drawer frame is fixed by the locking bolt. The locking bolt can be loosened to pull the drawer frame out of the filter box.

[0016] Preferably, the storage assembly includes a storage box and a discharge port disposed below the storage box, the storage box is connected to the filter box through a pipeline, valves are disposed on the discharge port and the outlet, and the detection assembly includes a high-performance liquid chromatograph, which is connected to the discharge port. The extract filtered out by the filter box directly enters the storage box from the pipeline, and the extract is output through the discharge port, and is detected using the high-performance liquid chromatograph.

[0017] Preferably, the supporting assembly comprises a bracket, a first auxiliary bracket and a second auxiliary bracket, the bracket is fixed to the tank body, the first auxiliary bracket and the second auxiliary bracket are both fixed to the bracket, wherein the first auxiliary bracket is located below the filter box, a first weight sensor is fixed on the first auxiliary bracket, and the second auxiliary bracket is located below the storage box, a second weight sensor is fixed on the second auxiliary bracket.

[0018] In summary, the present invention also includes a detection method of a freshwater product drug residue detection device, comprising the following steps: The crushed aquatic product sample and the extraction solvent are mixed using a mixing component to output a mixed liquid.

[0019] The mixed liquid outputted from the mixing component is filtered by the filtering component to output the extract and the matrix. The extract enters the storage component for storage, and the matrix remains in the filtering component.

[0020] The matrix and the extraction liquid are weighed respectively by a first weight sensor and a second weight sensor in the support assembly.

[0021] The drug residue in the extract is detected by the detection component.

[0022] Compared with the prior art, the present invention has the following beneficial effects: The present invention stirs and mixes aquatic product samples and extraction solvents through a mixing component to output a mixed solution, filters the mixed solution through a filtering component to output an extract, and a pull-out frame in the filtering component facilitates matrix processing. Finally, the concentration of residual drugs in the extract is detected through a detection module, without manual operation, effectively reducing the workload of workers and greatly improving the practicality of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 The three-dimensional structure of the present invention is shown in FIG. Figure 1 ; Figure 2 The three-dimensional structure of the present invention is shown in FIG. Figure 2 ; Figure 3 It is a schematic diagram of a partial cross-sectional structure of the present invention; Figure 4 This is a schematic diagram of the structure of the dismantling detection assembly of the present invention; Figure 5 This is a schematic diagram of the pull-out structure of the pull-out frame of the present invention; Figure 6 It is a schematic diagram of the process of the present invention.

[0024] In the figure: 100, tank body; 1001, first feeding port; 1002, second feeding port; 1003, discharge port; 1004, observation window; 101, rotating rod; 102, stirring blade; 103, scraper; 200, slide rail; 201, screw rod; 202, first drive motor; 203, slider; 204, connecting plate; 205, second drive motor; 300, filter box; 3001, screw hole; 3002, locking bolt; 301, pull-out frame; 3011, filter screen; 400, storage box; 401, discharge port; 500, high performance liquid chromatograph; 600, bracket; 601, first auxiliary frame; 6011, first weight sensor; 602, second auxiliary frame; 6021, second weight sensor. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0026] In the description of the present invention, it should be noted that the terms "vertical", "up", "down", "horizontal", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0027] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] See also Figure 1-5 The present invention provides a technical solution: a device for detecting drug residues in freshwater products, comprising a mixing component, a lifting component, a filtering component, a storage component, a detection component and a supporting component.

[0029] The lifting assembly is arranged on the side of the mixing assembly, the supporting assembly is arranged below the mixing assembly, the filtering assembly and the storage assembly are arranged on the inner side of the supporting assembly, the filtering assembly is located above the storage assembly, and the detecting assembly is arranged on the side of the supporting assembly.

[0030] The mixing component is used to stir and mix the aquatic product sample and the extraction solvent to output a mixed liquid; the lifting component is used to adjust the stirring depth inside the mixing component; the filtering component is used to filter the mixed liquid to output an extracted liquid; the storage component is used to store the extracted liquid; the detection module is used to detect the concentration of residual drugs in the extracted liquid; and the supporting component is used to support the filtering component and the storage component.

[0031] For further information, see Figure 1-3 The mixing assembly includes a tank body 100, a rotating rod 101, a stirring blade 102 and a scraper 103; the rotating rod 101 is located inside the tank body 100, the top of the rotating rod 101 passes through the tank body 100, the stirring blade 102 is fixed on the rotating rod 101, the scraper 103 is fixed at the end of the rotating rod 101, and the scraper 103 is in contact with the inner wall of the tank body 100.

[0032] The rotating rod 101 drives the stirring blade 102 to stir and mix the aquatic product sample and the extraction solvent, and the scraper 103 can prevent the sample from adhering to the inner wall of the tank body 100.

[0033] Furthermore, the tank body 100 is provided with a first feeding port 1001 and a second feeding port 1002 , a discharge port 1003 is provided below the tank body 100 , a valve is provided on the discharge port 1003 , and an observation window 1004 is provided on the front of the tank body 100 .

[0034] The first feed port 1001 is used for adding aquatic product samples, the second feed port 1002 is used for adding extraction solvents, and the discharge port 1003 is used for discharging the mixed liquid.

[0035] For further information, see Figure 4 The lifting assembly includes a slide rail 200, a screw rod 201, a first drive motor 202, a slider 203, a connecting plate 204 and a second drive motor 205; the slide rail 200 is fixed on the tank body 100, the screw rod 201 and the slider 203 are arranged on the inner side of the slide rail 200, the screw rod 201 passes through the slider 203, the screw rod 201 and the slide rail 200 are connected by rotation, the slider 203 and the screw rod 201 are connected by thread, the first drive motor 202 is fixed on the top of the slide rail 200, the drive shaft of the first drive motor 202 is connected to the screw rod 201, the connecting plate 204 is L-shaped and fixed on the slider 203, the second drive motor 205 is fixed on the connecting plate 204, and the drive shaft of the second drive motor 205 is connected to the rotating rod 101.

[0036] The second drive motor 205 drives the rotating rod 101 to rotate to cooperate with the stirring blade 102 for stirring and mixing. The first drive motor 202 drives the screw rod 201 to rotate, and the screw rod 201 drives the slider 203 to move, so that the slider 203 drives the rotating rod 101 to move up and down through the connecting plate 204, thereby adjusting the stirring depth.

[0037] For further information, see Figure 3 and Figure 5 The filter assembly includes a filter box 300 and a pull-out frame 301 inserted inside the filter box 300. A filter screen 3011 is provided at the bottom of the pull-out frame 301. The filter box 300 is connected to the discharge port 1003. The mixed liquid is discharged into the filter box 300 through the discharge port 1003. The mixed liquid is filtered by the filter screen 3011 on the pull-out frame 301 to filter the extract, and the matrix remains in the filter screen 3011.

[0038] Furthermore, a screw hole 3001 is opened on the side of the filter box 300 , and a locking bolt 3002 is threadedly connected to the inner thread of the screw hole 3001 , and the pull-out frame 301 is fixed by the locking bolt 3002 .

[0039] For further information, see Figure 1-2 The storage assembly includes a storage box 400 and a discharge port 401 disposed below the storage box 400. The storage box 400 is connected to the filter box 300 through a pipeline. The discharge port 401 and the discharge port 1003 are both provided with valves. The detection assembly includes a high-performance liquid chromatograph 500, which is connected to the discharge port 401. The extract filtered by the filter box 300 directly enters the storage box 400 from the pipeline, and the extract is output through the discharge port 401, and is detected by the high-performance liquid chromatograph 500.

[0040] For further information, see Figure 3 The support assembly includes a bracket 600, a first auxiliary bracket 601 and a second auxiliary bracket 602. The bracket 600 is fixed to the tank body 100. The first auxiliary bracket 601 and the second auxiliary bracket 602 are both fixed to the bracket 600. The first auxiliary bracket 601 is located below the filter box 300. A first weight sensor 6011 is fixed to the first auxiliary bracket 601. The second auxiliary bracket 602 is located below the storage box 400. A second weight sensor 6021 is fixed to the second auxiliary bracket 602.

[0041] In summary, please refer to Figure 6 The present invention also includes a detection method of a freshwater product drug residue detection device, comprising the following steps: The crushed aquatic product sample and the extraction solvent are mixed using a mixing component to output a mixed liquid.

[0042] The filtering component is used to filter the mixture output by the mixing component to output the extract and the matrix. The extract enters the storage component for storage, while the matrix remains in the filtering component.

[0043] The first weight sensor 6011 and the second weight sensor 6021 in the support component are respectively used to weigh the matrix and the extract.

[0044] The detection component is used to detect the drug residues in the extract.

[0045] In summary, when the device is in use, only the aquatic product sample and the extraction solvent need to be added into the tank body 100, and then the second driving motor 205 is started, so that the second driving motor 205 drives the rotating rod 101 to rotate, and the rotating rod 101 drives the stirring blade 102 and the scraping blade 103 to rotate. The stirring blade 102 is used to crush, stir and mix the aquatic product sample and the extraction solvent to output the mixture. The scraping blade 103 can prevent the mixture from adhering to the inner wall of the tank body 100. During the stirring process, the first driving motor 202 can be started to drive the lead screw 201 to rotate, and the lead screw 201 is used to drive the slider 203 to move, so that the slider 203 drives the rotating rod 101 to move up and down through the connecting plate 204, thereby adjusting the stirring depth. After mixing, the discharge port 1003 is opened, so that the mixture enters the filtering box 300, and the filter screen 3011 in the draw frame 301 is used to filter the mixture. The filtered extract enters the storage box 400, while the matrix remains in the filter screen 3011. After filtering, the first weight sensor 6011 and the second weight sensor 6021 are used to detect the filtering box 300 and the storage box 400, so as to detect the weights of the matrix and the extract. Then the high performance liquid chromatograph 500 is started to pump out the extract and detect the drug residues in the extract. The draw frame 301 can also be pulled out to process the matrix on the filter screen 3011.

[0046] It should be noted that the entire device is controlled by the total control button. Since the devices matched with the control button are common devices and belong to the existing mature technologies, the electrical connection relationship and the specific circuit structure thereof will not be elaborated herein.

[0047] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirits of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for detecting drug residues in freshwater products, characterized in that: It includes a mixing component, a lifting component, a filtering component, a storage component, a detection component and a supporting component; The lifting assembly is arranged at the side of the mixing assembly, the supporting assembly is arranged below the mixing assembly, the filtering assembly and the storage assembly are arranged inside the supporting assembly, the filtering assembly is located above the storage assembly, and the detecting assembly is arranged at the side of the supporting assembly; The mixing component is used to stir and mix the aquatic product sample and the extraction solvent to output the mixed liquid; the lifting component is used to adjust the stirring depth inside the mixing component; the filtering component is used to filter the mixed liquid to output the extraction liquid; The storage component is used to store the extraction liquid; The detection module is used to detect the concentration of residual drugs in the extract; the support component is used to support the filtering component and the storage component.

2. A freshwater product drug residue detection device according to claim 1, characterized in that: The mixing assembly comprises a tank body (100), a rotating rod (101), a stirring blade (102) and a scraper (103); The rotating rod (101) is located inside the tank body (100), the top end of the rotating rod (101) passes through the tank body (100), the stirring blade (102) is fixed on the rotating rod (101), the scraper (103) is fixed on the end of the rotating rod (101), and the scraper (103) is in contact with the inner wall of the tank body (100).

3. A freshwater product drug residue detection device according to claim 2, characterized in that: The tank body (100) is provided with a first feeding port (1001) and a second feeding port (1002), a discharge port (1003) is provided below the tank body (100), a valve is provided on the discharge port (1003), and an observation window (1004) is provided on the front of the tank body (100).

4. A freshwater product drug residue detection device according to claim 1, characterized in that: The lifting assembly comprises a slide rail (200), a screw rod (201), a first drive motor (202), a slider (203), a connecting plate (204) and a second drive motor (205); The slide rail (200) is fixed on the tank body (100), the screw rod (201) and the slider (203) are arranged on the inner side of the slide rail (200), the screw rod (201) passes through the slider (203), the screw rod (201) and the slide rail (200) are connected by rotation, and the slider (203) and the screw rod (201) are connected by thread. The first drive motor (202) is fixed on the top of the slide rail (200), the drive shaft of the first drive motor (202) is connected to the screw rod (201), the connecting plate (204) is L-shaped and fixed on the slider (203), the second drive motor (205) is fixed on the connecting plate (204), and the drive shaft of the second drive motor (205) is connected to the rotating rod (101).

5. A freshwater product drug residue detection device according to claim 1, characterized in that: The filter assembly comprises a filter box (300) and a pull-out frame (301) inserted into the filter box (300); a filter screen (3011) is provided at the bottom of the pull-out frame (301); and the filter box (300) is connected to the discharge port (1003).

6. A freshwater product drug residue detection device according to claim 1, characterized in that: The filter box (300) is provided with a screw hole (3001) on the side thereof, and a locking bolt (3002) is connected to the inner thread of the screw hole (3001), and the drawer frame (301) is fixed by the locking bolt (3002).

7. A freshwater product drug residue detection device according to claim 1, characterized in that: The storage component comprises a storage box (400) and a discharge port (401) arranged below the storage box (400); the storage box (400) and the filter box (300) are connected via a pipeline; valves are provided on the discharge port (401) and the discharge port (1003); and the detection component comprises a high-performance liquid chromatograph (500); the high-performance liquid chromatograph (500) is connected to the discharge port (401).

8. A device for detecting drug residues in freshwater products according to claim 1, characterized in that: The support assembly comprises a bracket (600), a first auxiliary bracket (601) and a second auxiliary bracket (602); the bracket (600) is fixed to the tank body (100); the first auxiliary bracket (601) and the second auxiliary bracket (602) are both fixed to the bracket (600); the first auxiliary bracket (601) is located below the filter box (300); a first weight sensor (6011) is fixed to the first auxiliary bracket (601); the second auxiliary bracket (602) is located below the storage box (400); a second weight sensor (6021) is fixed to the second auxiliary bracket (602).

9. The detection method of a freshwater product drug residue detection device according to claims 1-8, characterized in that: The following steps are involved: S1. Using a mixing component to mix the crushed aquatic product sample and the extraction solvent to output a mixed liquid; S2, using the filtering component to filter the mixed liquid output by the mixing component to output the extract and the matrix, the extract enters the storage component for storage, and the matrix remains in the filtering component; S3, weighing the matrix and the extract respectively by a first weight sensor and a second weight sensor in the support assembly; S4. Detect drug residues in the extract using a detection component.

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