Sample analyzer, storage device and analysis system

By designing an automated storage and scheduling system in the sample analyzer, the problem of inconvenient operation of quality control/calibrator in the prior art is solved, the stability and validity period of quality control/calibrator are guaranteed, and the degree of automation and reliability of the analyzer is improved.

CN120028556APending Publication Date: 2025-05-23SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
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Patent Information

Application Number
CN202311562895.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2023-11-21
Publication Date
2025-05-23

AI Technical Summary

Technical Problem

Existing sample analyzers require the QC/calibrator to be removed from the refrigerator for testing, which is inconvenient to operate and affects the stability of the QC/calibrator.

Method used

A sample analyzer is designed, a freezer chamber containing a storage device, which is used to store quality control products/calibrators, and is equipped with a dispatching mechanism and a controller to realize the automatic transfer of quality control products/calibrators, ensuring that they are automatically taken out for testing when needed. When the freezer chamber needs to melt frost, the control dispatching mechanism will remove all the containers and perform melt frost operation.

Benefits of technology

It realizes the automated management of quality control products/calibrators, reduces the complexity and error rate of manual operation, ensures the stability and validity of quality control products/calibrators, and improves the degree of automation and reliability of the analyzer.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides a sample analyzer, a storage device and an analysis system. The sample analyzer comprises: a sample supply mechanism for carrying a sample container containing a sample to be measured; the reagent supply mechanism is used for bearing a reagent container filled with a reagent; a sample dispensing mechanism for adding a sample into the reaction vessel; the reagent separate injection mechanism is used for adding the reagent in the reagent accommodating cavity into the corresponding reaction container; the detection device is used for detecting the reaction liquid containing the sample and the reagent in the reaction container to obtain a detection result; the storage device at least comprises a freezing bin, and the freezing bin is used for storing the first container and providing a refrigeration environment below zero DEG C; the dispatching mechanism is used for dispatching the first container into and / or out of the freezing bin; and the controller is used for controlling the scheduling mechanism to call out all the first containers in the freezing bin needing to be defrosted and controlling the freezing bin to perform defrosting operation under the condition that the freezing bin storing the first containers needs to be defrosted.
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Description

Technical Field

[0001] The present application relates to the field of in vitro diagnostic technology, and in particular to a sample analyzer, a storage device, and an analysis system. Background Art

[0002] In the related art, the quality control products / calibration products of the sample analyzer need to be stored at low temperature in an additional refrigerator to ensure their stability. When the sample analyzer needs to be tested, the quality control products / calibration products are taken out of the refrigerator and put into the machine. This is inconvenient to operate. Summary of the invention

[0003] In view of this, embodiments of the present application are intended to provide a sample analyzer, a storage device, and an analysis system.

[0004] A first aspect of an embodiment of the present application provides a sample analyzer, comprising:

[0005] A sample supply mechanism, used for carrying a sample container containing a sample to be measured;

[0006] A reagent supply mechanism, used for carrying a reagent container containing a reagent;

[0007] A sample dispensing mechanism, used for adding the sample into a reaction container;

[0008] A reagent dispensing mechanism, used for adding the reagent in the reagent chamber into the corresponding reaction container;

[0009] A detection device, used for detecting the reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result;

[0010] The storage device comprises at least one freezing chamber, wherein the freezing chamber is used to store the first container containing the quality control product / calibration product and provide a sub-zero refrigeration environment;

[0011] A dispatching mechanism, used for transferring the first container into and / or out of the freezing warehouse;

[0012] The controller is used to control the scheduling mechanism to call out all the first containers in the freezing bin that need to be defrosted, and control the freezing bin to perform a defrosting operation when the freezing bin storing the first container needs to be defrosted.

[0013] A second aspect of an embodiment of the present application provides a sample analyzer, comprising:

[0014] A sample supply mechanism, used for carrying a sample container containing a sample to be measured;

[0015] A reagent supply mechanism, used for carrying a reagent container containing a reagent;

[0016] A sample dispensing mechanism, used for adding the sample into a reaction container;

[0017] A reagent dispensing mechanism, used for adding the reagent in the reagent chamber into the corresponding reaction container;

[0018] A detection device, used for detecting the reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result;

[0019] A storage device, comprising a freezing chamber and a heat insulation component, wherein the freezing chamber is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment; the heat insulation component has a first state and a second state, wherein in the first state, the heat insulation component is covered around the first container to insulate the first container from the inner wall of the freezing chamber; in the second state, the heat insulation component is removed from around the first container to release the heat insulation between the first container and the inner wall of the freezing chamber;

[0020] The controller is used to control the freezing of the freezer compartment and control the thermal insulation component to be in the second state during the refrigeration process of the freezer compartment; it is also used to control the thermal insulation component to switch to the first state and control the freezer compartment that needs to be defrosted to perform a defrosting operation when the freezer compartment needs to be defrosted.

[0021] A third aspect of an embodiment of the present application provides a storage device, including:

[0022] At least one freezing chamber, the freezing chamber is used to store the first container containing the quality control product / calibration product and provide a sub-zero refrigeration environment;

[0023] The controller is used for controlling the freezing bin that needs to be defrosted to perform a defrosting operation when the freezing bin storing the first container needs to be defrosted and all the first containers in the freezing bin are taken out.

[0024] A fourth aspect of an embodiment of the present application provides a storage device, including:

[0025] A freezing chamber and a heat insulation component, wherein the freezing chamber is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment; the heat insulation component has a first state and a second state, in the first state, the heat insulation component is covered around the first container to insulate the first container from the inner wall of the freezing chamber; in the second state, the heat insulation component is removed from around the first container to release the heat insulation between the first container and the inner wall of the freezing chamber;

[0026] The controller is used to control the freezing of the freezer compartment and control the thermal insulation component to be in the second state during the refrigeration process of the freezer compartment; it is also used to control the thermal insulation component to switch to the first state and control the freezer compartment that needs to be defrosted to perform a defrosting operation when the freezer compartment needs to be defrosted.

[0027] A fifth aspect of the embodiments of the present application provides an analysis system, comprising an analyzer, a conveying mechanism, and the storage device according to any one of the above embodiments, wherein the conveying mechanism is used to transfer the first container in the freezing chamber to the analyzer for quality control / calibration testing by the analyzer;

[0028] Wherein, the analyzer comprises:

[0029] A sample supply mechanism, used for carrying a sample container containing a sample to be measured;

[0030] A reagent supply mechanism, used for carrying a reagent container containing a reagent;

[0031] A sample dispensing mechanism, used for adding the sample into a reaction container;

[0032] A reagent dispensing mechanism, used for adding the reagent in the reagent chamber into the corresponding reaction container;

[0033] The detection device is used to detect the reaction solution containing the sample and the reagent in the reaction container to obtain the sample detection result.

[0034] The sample analyzer of the embodiment of the present application includes a storage device, a scheduling mechanism and a controller. The freezing chamber of the storage device can be used to store quality control products / calibration products that need to be stored at low temperature, so as to ensure the stability of the quality control products / calibration products. When the sample analyzer needs to be tested or the test is completed, the scheduling mechanism can automatically transfer the first container containing the quality control product / calibration product into or out of the freezing chamber, which is convenient for taking out, putting back and loading the quality control product / calibration product, and is conducive to the automatic completion of the quality control / calibration test process. In addition, when the freezing chamber needs to be defrosted, the controller can also control the scheduling mechanism to transfer all the first containers in the freezing chamber, and then perform the defrosting operation, which has a higher degree of automation, and can also reduce the impact on the stability and validity period of the quality control product / calibration product caused by the temperature increase during defrosting due to the failure to take out the first container, and has better reliability. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 A simplified schematic diagram of a sample analyzer according to an embodiment of the present application;

[0036] Figure 2 A simplified schematic diagram of a freezing chamber according to an embodiment of the present application;

[0037] Figure 3 A simplified schematic block diagram of a freezing chamber according to an embodiment of the present application;

[0038] Figure 4 A schematic diagram of a defrosting method for a sample analyzer according to an embodiment of the present application;

[0039] Figure 5 for Figure 4 A flow chart of the step of obtaining defrost requirement information of a freezing chamber in the method shown;

[0040] Figure 6 The present invention is a flow chart of a method for starting a defrosting operation of a freezing chamber of a sample analyzer according to an embodiment of the present application.

[0041] Description of Reference Numerals

[0042] 1-sample supply mechanism; 2-reagent supply mechanism; 3-sample dispensing mechanism; 4-reagent dispensing mechanism; 5-mixing mechanism; 6-reaction component; 7-storage device; 71-freezing chamber; 711-semiconductor refrigeration plate; 712-fan; 72-insulation chamber; 73-discharge port; 8-controller; 9-power supply circuit. DETAILED DESCRIPTION

[0043] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0044] The various specific technical features described in the specific embodiments can be combined in any suitable manner without contradiction, for example, different embodiments and technical solutions can be formed by combining different specific technical features. In order to avoid unnecessary repetition, various possible combinations of the specific technical features in the present invention will not be described separately.

[0045] In the following description, the terms "first\second\..." are only used to distinguish different objects, and do not mean that the objects have the same or related points. It should be understood that the directions "above", "below", "outside" and "inside" are all directions in normal use, and the directions "left" and "right" refer to the left and right directions shown in the specific corresponding schematic diagrams, which may be the left and right directions in normal use or not.

[0046] It should be noted that the terms "comprises", "includes" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also includes other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the sentence "comprises a ..." does not exclude the presence of other identical elements in the process, method, article or device including the element. "Multiple" means greater than or equal to two.

[0047] like Figure 1 As shown, an embodiment of the present application provides a sample analyzer, including a sample supply mechanism 1, a reagent supply mechanism 2, a sample dispensing mechanism 3, a reagent dispensing mechanism 4 and a detection device.

[0048] The sample supply mechanism 1 is used to carry a sample container containing a sample to be measured. The sample supply mechanism 1 can be a sample tray, which includes a plurality of sample positions such as sample tubes. The sample tray can dispatch the sample to a corresponding position by rotating its tray structure, for example, a position for the sample dispensing mechanism 3 to absorb the sample. Of course, the sample supply mechanism 1 can also be in other shapes.

[0049] The reagent supply mechanism 2 is used to carry a reagent container containing a reagent. In some embodiments, the reagent supply mechanism 2 can be a reagent disk, which is a disc-shaped structure with multiple positions for carrying reagent bottles. The reagent supply mechanism 2 can rotate and drive the reagent bottles it carries to rotate, and is used to rotate the reagent bottles to a specific position, such as a position where the reagent is sucked by the reagent dispensing mechanism 4.

[0050] The sample dispensing mechanism 3 is used to add the sample to the reaction container. Exemplarily, the sample dispensing mechanism 3 includes a moving part and a sample needle disposed on the moving part, and the moving part is used to drive the sample needle to move between different operating positions to absorb or discharge the sample. For example, the sample needle moves to absorb the sample carried by the sample supply mechanism 2, moves to the reaction container to be added, and discharges the sample into the reaction container.

[0051] The reagent dispensing mechanism 4 is used to add the reagent in the reagent container to the corresponding reaction container. For example, the reagent dispensing mechanism 4 is configured with a reagent needle, which moves to absorb the reagent in the reagent container carried by the reagent supply mechanism 2, moves to the reaction container to be added with the reagent, and discharges the reagent into the reaction container.

[0052] The detection device is used to detect the reaction solution containing the sample and the reagent in the reaction container to obtain the sample detection result. For example, the detection device performs optical measurement analysis on the reaction solution to be tested, and calculates the concentration of the component to be tested in the sample through the calibration curve.

[0053] It should be noted that the optical measurement analysis may be immunoassay, biochemical analysis, coagulation analysis, blood rheology analysis, and the like.

[0054] Exemplarily, in some embodiments, the sample analyzer further comprises a mixing mechanism 5, which is used to mix the reaction liquid in the reaction container. Exemplarily, the mixing mechanism 5 is provided with a stirring rod, which is used to mix the reaction liquid in the reaction container.

[0055] The number of the mixing mechanism 5 can be one or more.

[0056] For example, in some embodiments, the sample analyzer further includes a reaction component 6, which has at least one placement position, and the placement position is used to place a reaction container and incubate a reaction liquid in the reaction container, wherein the reaction liquid is obtained by mixing a sample provided by the sample dispensing mechanism 3 and a reagent provided by the reagent dispensing mechanism 4. For example, the reaction component 6 may be a reaction disk, which is provided in a disk-shaped structure and has one or more placement positions for placing reaction containers, and the reaction disk can rotate and drive the reaction containers in its placement positions to rotate, so as to schedule the reaction containers in the reaction disk and incubate the reaction liquid in the reaction containers.

[0057] The sample analyzer also includes a storage device 7 and a scheduling mechanism. The storage device 7 includes at least one freezing chamber 71, which is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment, so that the quality control product / calibration product that needs to be frozen can be frozen and stored to ensure the stability of the quality control product / calibration product. For example, the freezing chamber 71 can provide a freezing storage temperature of minus 10° to minus 30°.

[0058] It should be noted that after the quality control product / calibrator is dispensed into the first container, it needs to be stored at a low temperature below zero degrees. In general, the samples provided by the sample supply mechanism 1 and the reagents provided by the reagent supply mechanism 2 only need to be stored at a refrigeration temperature above zero degrees, and do not need to be stored at a freezing temperature below zero degrees.

[0059] The embodiment of the present application does not specifically limit the number of freezing bins 71, which may be one, two or more.

[0060] The dispatch mechanism is used to transfer the first container into and / or out of the freezing chamber 71. In this way, when the sample analyzer needs to be tested or the test is completed, the dispatch mechanism can automatically transfer the first container containing the quality control product / calibration product into or out of the freezing chamber 71, which is convenient for the removal, return and loading of the quality control product / calibration product, more convenient for the user to operate, and conducive to the automatic completion of the quality control / calibration test process.

[0061] The dispatching mechanism includes but is not limited to a robotic arm.

[0062] When the freezing chamber 71 is in a freezing state, the freezing chamber 71 is always kept in a low-temperature freezing environment below zero, while the ambient temperature and humidity of the outside environment are higher than the temperature and humidity of the freezing chamber 71. When the dispatching mechanism transfers in or out the first container stored in the freezing chamber 71, the environment in the freezing chamber 71 will be connected to the outside environment. Therefore, the low-temperature and dry environment in the freezing chamber 71 will produce air convection exchange with the high-temperature and high-humidity environment in the outside. At this time, the high-temperature and high-humidity air in the outside will enter the inside of the freezing chamber 71, and frost will occur when it encounters cold inside the freezing chamber 71. If the degree of frost in the freezing chamber is high, the heat transfer efficiency of the freezing chamber will be deteriorated, resulting in the temperature of the first container stored in the freezing chamber being difficult to maintain at the target temperature, which may affect the stability and validity period of the quality control product / calibration product stored in the first container. Therefore, it is necessary to regularly defrost the freezing chamber 71 to ensure that the first container stored in the freezing chamber 71 can always be maintained at the target temperature.

[0063] When the freezing chamber 71 is defrosted, the freezing chamber 71 needs to be heated up so that the frost formed in the freezing chamber 71 can melt into liquid and be discharged from the freezing chamber 71 through the discharge port 73, or the frost in the freezing chamber 71 needs to be defrosted manually. Whether it is heating up or manual defrosting, the temperature in the freezing chamber 71 will inevitably change, so that the first container stored in the freezing chamber 71 cannot be maintained at the target temperature. Therefore, in one embodiment of the present application, before the freezing chamber 71 is defrosted, all the first containers stored in the freezing chamber 71 to be defrosted need to be taken out before the defrosting operation is performed, so as to ensure the stability of the quality control product / calibration product stored in the first container.

[0064] Therefore, the sample analyzer of the embodiment of the present application also includes a controller 8, which is used to control the scheduling mechanism to call out all the first containers in the freezing bin 71 that need to be defrosted, and control the freezing bin 71 to perform a defrosting operation.

[0065] In this way, the user can set the program in advance and store it in the controller 8, so that when the freezing chamber 71 needs to be defrosted, the controller 8 can automatically control the scheduling mechanism to call out the first container, and after all the first containers are called out, control the freezing chamber 71 to perform the defrosting operation, which is conducive to the automatic completion of the defrosting operation, which can effectively save labor costs, and can also reduce the impact of the temperature increase during defrosting caused by the failure to take out the first container on the stability and validity period of the quality control product / calibration product, and has better reliability. The controller 8 includes but is not limited to a processor and a storage medium storing a computer program.

[0066] In some embodiments, the freezing warehouse 71 includes a warehouse body and a refrigeration structure, the refrigeration structure is used to provide a refrigeration environment for the warehouse body, and the warehouse body is used to store the first container.

[0067] In this way, the freezing chamber 71 can provide a sub-zero refrigeration environment for the first container stored in the chamber through the refrigeration structure, so that the quality control product / calibration product can be frozen and stored in a low-temperature environment below zero degrees, thereby ensuring its stability.

[0068] The specific type of the refrigeration structure is not limited, as long as it can provide a preset refrigeration environment for the warehouse.

[0069] For example, in some embodiments, Figure 2 and Figure 3 As shown, the storage device 7 includes at least two freezing chambers 71, and the refrigeration structures of the freezing chambers 71 are independent of each other, so that the refrigeration structure of any freezing chamber 71 can be used independently.

[0070] On the one hand, the more freezing bins 71 there are, the more first containers can be stored, thereby ensuring a sufficient number of quality control products / calibration products to meet the needs of quality control / calibration tests. On the other hand, since the refrigeration structures of each freezing bin 71 are independent of each other, each bin body will not affect the temperature of another bin body during the defrosting process. When the degree of frost in one of the freezing bins 71 is high and a defrosting operation is required, the controller 8 can control the scheduling mechanism to transfer out all the first containers in the bin body of the freezing bin 71 that needs to be defrosted, and transfer them to another freezing bin 71 that does not need to be defrosted temporarily. In this way, there is no need to set up an additional preservation mechanism, and it is also possible to ensure that all the first containers are properly stored during the defrosting operation in one of the freezing bins 71, so that the first containers can be maintained at the target temperature without being affected by the defrosting of the freezing bin 71 during the storage process.

[0071] It should be noted that the more the number of freezing bins 71 is, the more freezing bins 71 can perform defrosting operations at the same time. The embodiment of the present application does not specifically limit the number of freezing bins 71, and can be set according to production costs and actual use requirements.

[0072] It should be noted that the defrosting operation of the freezing chamber 71 can be performed by simply stopping freezing in the freezing chamber 71 and then defrosting by natural heating, or by heating the freezing chamber 71 while stopping freezing and then defrosting by heating.

[0073] For example, in some embodiments, the freezing chamber 71 includes a heating structure, and controlling the freezing chamber 71 to perform a defrosting operation includes: controlling the refrigeration structure to stop refrigeration, and controlling the heating structure to heat. In this way, when a defrosting operation is required, the controller 8 can first control the refrigeration structure to stop refrigeration, and then control the heating structure to heat, so that the temperature in the freezing chamber 71 is increased through the heating structure, so that the frost gradually melts into liquid and is discharged from the discharge port 73, thereby achieving a rapid defrosting effect.

[0074] The specific type of the heating structure is not limited, as long as it can melt the frost in the freezing chamber, for example, it can be a resistance heating structure, a condenser of a heat pump system, etc.

[0075] In other embodiments, controlling the freezing chamber 71 to perform a defrosting operation includes: controlling the refrigeration structure to stop refrigeration. In this way, when a defrosting operation is required, the controller 8 can control the refrigeration structure to stop refrigeration, so that the temperature in the freezing chamber 71 gradually increases in a natural temperature rise manner after the refrigeration stops, thereby gradually melting the frost. Alternatively, after the controller 8 controls the refrigeration structure to stop refrigeration, the user can manually remove the frost in the freezing chamber 71 to perform a defrosting process.

[0076] In some embodiments, Figure 2 As shown, the freezing chamber 71 includes a semiconductor refrigeration chip 711, the sample analyzer includes a power supply circuit 9, the semiconductor refrigeration chip 711 is connected to the power supply circuit 9, and the controller 8 is used to control the direction of the voltage loaded on the semiconductor refrigeration chip by the power supply circuit 9, thereby controlling the semiconductor refrigeration chip 711 to cool or heat the freezing chamber 71.

[0077] The semiconductor cooling sheet 711 is also called a thermoelectric cooling sheet. Semiconductor materials have the Peltier effect (thermoelectric effect). When current passes through a thermocouple made of two different semiconductor materials in series, heat can be absorbed and released at both ends of the thermocouple to achieve the purpose of cooling or heating. The semiconductor cooling sheet is composed of two thermocouples made of different materials. When current passes through these two materials, the temperature of one material will rise and the temperature of the other material will drop. In this way, by controlling the direction of the voltage, the direction of the current can be controlled, thereby achieving a cooling or heating effect for a specific environment.

[0078] For example, the semiconductor cooling sheet 711 includes a first heat exchange end, a first heat exchange end, a first wiring port, and a second wiring port. The first wiring port and the second wiring port are used to connect to the circuit. The first heat exchange end is close to the side wall of the warehouse or is a part of the inner wall of the warehouse. When the potential of the first wiring port is higher than the potential of the second wiring port, the first heat exchange end cools and the second heat exchange end heats. At this time, the first heat exchange end is equivalent to the above-mentioned cooling structure. When the voltage is reversed, the potential of the first wiring port is lower than the potential of the second wiring port, the first heat exchange end heats and the second heat exchange end cools. At this time, the first heat exchange end is equivalent to the above-mentioned heating structure.

[0079] In this way, when defrosting is required, the freezing chamber 71 does not need to be provided with an additional heating structure, and the freezing chamber 71 can be heated by changing the direction of the voltage, which reduces the number of parts, saves assembly costs, and is conducive to the miniaturization and integration of the overall refrigeration and heating structure, so that the freezing chamber 71 can have more space for storing the first container. In addition, the semiconductor refrigeration sheet 711 has low power consumption, compact structure, and long service life.

[0080] In some embodiments, the freezing chamber 71 further includes a fan 712, and the controller 8 can control the rotation of the fan 712 when the freezing chamber 71 is heating and defrosting. In this way, the defrosting speed can be accelerated, so that the freezing chamber 71 can complete the defrosting operation in a shorter time.

[0081] In some embodiments, the controller 8 is used to: when one of the freezing bins 71 storing the first container needs to be defrosted, control the scheduling mechanism to schedule at least part of the first container in the freezing bin 71 that needs to be defrosted to other freezing bins 71, and control the freezing bin 71 that needs to be defrosted to perform the defrosting operation.

[0082] In this way, when one of the freezing chambers needs to be defrosted, at least part of the first containers in the freezing chamber that are not needed temporarily can be dispatched to other freezing chambers to ensure that these first containers that are not needed temporarily are always in a good low-temperature storage state, and the remaining first containers can be dispatched to other specified positions according to usage requirements, such as a re-thawing position, a sample position, an insulation chamber, or a liquid aspiration position of the first dispensing mechanism, etc.

[0083] Those skilled in the art should understand that the controller 8 can also dispatch all first containers in the freezing bin that need to perform defrosting operations to other freezing bins.

[0084] In some embodiments, such as Figure 3 As shown, the storage device 7 also includes an insulation bin 72, and the controller 8 is used to control the scheduling mechanism to schedule at least part of the first container in the freezing bin 71 to the insulation bin 72 and control the freezing bin 71 to perform a defrosting operation when the freezing bin 71 storing the first container needs to be defrosted.

[0085] In this way, it is possible to ensure that the first container maintains the target temperature in the insulation chamber 72, thereby ensuring the stability of the quality control products / calibration products stored in the first container so that they will not be affected by the defrosting process of the freezing chamber 71.

[0086] The specific type of the heat preservation chamber 72 is not limited, as long as it can maintain the target temperature of the first container.

[0087] In some embodiments, the sample analyzer includes a first dispensing mechanism, and the controller 8 is used to control the scheduling mechanism to schedule at least part of the first container in the freezing bin 71 that needs to defrost to the aspiration position of the first dispensing mechanism of the sample analyzer when the freezing bin 71 storing the first container needs to defrost. The first dispensing mechanism is used to add the quality control product / calibration product in the first container scheduled to the aspiration position to the corresponding reaction container to perform quality control / calibration testing.

[0088] In this way, when the freezing chamber 71 needs to be defrosted and the quality control product / calibration product in the first container needs to be used for quality control / calibration testing, the first container stored in the freezing chamber 71 can be used first, and the first container in the freezing chamber 71 can be dispatched to the liquid aspiration position of the first dispensing mechanism, and the quality control product / calibration product can be added to the corresponding reaction container through the first dispensing mechanism, so as to directly perform subsequent quality control / calibration testing, and then the quality control product / calibration product stored in the first container in the freezing chamber 71 can be properly used without affecting the defrosting operation of the freezing chamber 71. If the first container in the freezing chamber 71 that needs to be defrosted is not fully used, the remaining first containers can be dispatched to other freezing chambers 71 or insulation chambers 72 for freezing and insulation treatment as needed.

[0089] In some embodiments, the first dispensing mechanism and the sample dispensing mechanism 3 are the same mechanism. In this embodiment, the sample dispensing mechanism 3 is used to dispense the quality control material / calibration material in the first container in addition to dispensing the sample. In other embodiments, the first dispensing mechanism and the sample dispensing mechanism 3 are two independent and different mechanisms.

[0090] In some embodiments, in addition to detecting the reaction solution containing samples and reagents in the reaction container, the detection device is also used to detect the mixed solution containing quality control products / calibration products and reagents in the reaction container to obtain quality control / calibration test results.

[0091] In some embodiments, the sample analyzer includes a timing module, which is used to record the interval time from the last defrosting of the freezing chamber 71. The controller 8 is used to control the scheduling mechanism to call out all the first containers in the freezing chamber 71 that need to be defrosted when the interval time reaches a preset threshold, and then control the freezing chamber 71 that needs to be defrosted to perform a defrosting operation.

[0092] The longer the interval between defrosting of the freezing chamber 71, the more water vapor may enter the freezing chamber 71, and the more serious the frost in the freezing chamber 71 may be. When the interval reaches a preset threshold, it indicates that the freezing chamber 71 needs to be defrosted. Therefore, the sample analyzer can be provided with a timing module, which can automatically record the interval between the freezing chamber 71 and the last defrosting, so that the controller 8 can automatically control the freezing chamber 71 to call out the first container in the freezing chamber 71 when the defrosting operation is required, and perform the corresponding defrosting operation, which has a higher degree of automation, and can also effectively save energy while timely cleaning the frost.

[0093] The preset threshold of the interval time can be specifically set according to the frequency of use of the freezing chamber 71, the number of times the cover is opened, the length of time the cover is opened, etc. If the frequency of use of the freezing chamber 71 is higher, the number of times the cover is opened, and the length of time the cover is opened is longer, the preset threshold of the interval time should be shorter, and vice versa, the preset threshold of the interval time should be longer.

[0094] In other embodiments, the timing module is used to record the cumulative opening time of the freezer bin 71 since the last defrost, and the controller 8 is used to control the scheduling mechanism to call out all the first containers in the freezer bin 71 that need to be defrosted when the cumulative opening time reaches a preset threshold, and then control the freezer bin 71 that needs to be defrosted to perform the defrost operation.

[0095] The longer the freezer compartment 71 is opened, the more outside air will enter the freezer compartment, which will form more water vapor in the freezer compartment 71, and then form more frost, and the shorter the defrosting cycle will be. When the cumulative opening time reaches a preset threshold, it means that the freezer compartment 71 needs to be defrosted. Therefore, the timing module can be used to automatically record the cumulative opening time of the freezer compartment 71, so that the controller 8 can automatically control the freezer compartment 71 to call out the first container in the freezer compartment 71 when a defrosting operation is required, and perform the corresponding defrosting operation, while ensuring that the frost can be handled in time, avoiding frequent defrosting, thereby protecting the refrigeration structure and heating structure of the freezer compartment 71.

[0096] In some embodiments, the sample analyzer includes a detection module, which is used to detect environmental parameters outside the freezing chamber 71 and obtain environmental parameter information, wherein the environmental parameters include at least one of temperature and humidity, and the controller 8 is used to adjust the preset threshold according to the environmental parameter information.

[0097] The higher the humidity outside the freezing chamber 71, the more water vapor will enter the freezing chamber 71. Similarly, the higher the ambient temperature outside the freezing chamber 71, the more water vapor will be contained in the air. Therefore, when the temperature and / or humidity outside the freezing chamber 71 is higher, the faster the frost will form inside the freezing chamber 71, and the shorter the defrosting cycle will be. When the temperature or humidity outside the freezing chamber 71 is lower, the slower the frost will form inside the freezing chamber 71, and the longer the defrosting cycle will be. Therefore, by detecting the environmental parameters outside the freezing chamber 71 through the detection module, the controller 8 can automatically adjust the threshold according to the external environmental parameter information in an automated manner, effectively saving energy while ensuring that the freezing chamber 71 can perform defrosting operations in a timely manner.

[0098] In some embodiments, the sample analyzer includes a detection component for detecting frost information in the freezing bin 71. The controller 8 is used to control the scheduling mechanism to call out all first containers in the freezing bin 71 that need to be defrosted when the frost information reaches a preset condition, and then control the freezing bin 71 to perform a defrosting operation.

[0099] In this way, the frost information in the freezing chamber 71 can be directly detected by the detection component, and the corresponding defrosting operation can be performed according to the frost information.

[0100] Exemplarily, the frosting information may be, for example, the thickness of frost in the freezing chamber 71 , and the preset condition may be, for example, the thickness of frost that may affect the heat transfer efficiency in the freezing chamber 71 .

[0101] The embodiment of the present application provides a sample analyzer, which includes a sample supply mechanism 1 , a reagent supply mechanism 2 , a sample dispensing mechanism 3 , a reagent dispensing mechanism 4 , a detection device, a storage device 7 and a controller 8 .

[0102] The sample supply mechanism 1 is used to carry a sample container containing a sample to be measured.

[0103] The reagent supply mechanism 2 is used to carry a reagent container containing a reagent.

[0104] The sample dispensing mechanism 3 is used to add the sample into the reaction container.

[0105] The reagent dispensing mechanism 4 is used to add the reagent in the reagent chamber into the corresponding reaction container.

[0106] The detection device is used to detect the reaction liquid containing the sample and the reagent in the reaction container to obtain the sample detection result.

[0107] The storage device 7 includes a freezing chamber 71 and a heat insulation component. The freezing chamber is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment. The heat insulation component has a first state and a second state. In the first state, the heat insulation component is arranged around the first container to insulate the first container and the inner wall of the freezing chamber 71. In the second state, the heat insulation component is removed from around the first container to release the heat insulation between the first container and the inner wall of the freezing chamber.

[0108] The controller is used to control the freezing of the freezer compartment 71 and control the insulation component to be in the second state during the refrigeration process of the freezer compartment. It is also used to control the insulation component to switch to the first state and control the freezer compartment 71 that needs to be defrosted to perform the defrosting operation when the freezer compartment 71 needs to be defrosted.

[0109] In this way, when the freezing chamber 71 needs to be defrosted, the controller 8 can automatically control the insulation component to cover the first container so that the first container will not be affected by the heating and defrosting of the freezing chamber 71. The target temperature can be maintained under the action of the insulation component, thereby ensuring the stability of the quality control products / calibration products stored in the first container.

[0110] In addition, when the freezing chamber 71 needs to perform a defrosting operation, it is only necessary to cover the thermal insulation component around the first container, and when the freezing chamber 71 completes the defrosting operation and performs the refrigeration process, the thermal insulation component can be removed. There is no need to set up an additional scheduling mechanism, and defrosting is more convenient and quick, which is conducive to user operation.

[0111] The specific type of the heat insulation component is not limited, as long as the first container housed therein can be maintained at a target temperature.

[0112] It should be noted that when the heat insulation component is in the first state, the heat insulation component can be located inside the freezing chamber or outside the freezing chamber.

[0113] The embodiment of the present application provides a storage device 7, which includes at least one freezing bin 71 and a controller 8. The freezing bin 71 is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment. The controller 8 is used to control the freezing bin that needs to be defrosted to perform a defrosting operation when the freezing bin 71 storing the first container needs to be defrosted and all the first containers in the freezing bin 71 are taken out.

[0114] In this way, when it is necessary to defrost the freezing bin 71, the controller 8 can automatically control the freezing bin 71 to perform the defrost operation after all the first containers are taken out, which is conducive to the automated completion of the defrost operation, can effectively save labor costs, and can also reduce the impact of the temperature increase during defrosting due to the failure to take out the first container on the stability and shelf life of the quality control product / calibration product, thereby improving reliability.

[0115] In some embodiments, the storage device itself may be included in the sample analyzer and is a module in the sample analyzer, and the first container stored in the storage device is scheduled by the scheduling mechanism in the sample analyzer. In other embodiments, the storage device may also be provided separately and cascaded with the sample analyzer to form an analysis system, and the first container stored in the storage device is scheduled by a separate transmission mechanism or by the scheduling mechanism of the sample analyzer.

[0116] In some embodiments, the freezing warehouse 71 includes a warehouse body and a refrigeration structure, the refrigeration structure is used to provide a refrigeration environment for the warehouse body, and the warehouse body is used to store the first container.

[0117] Specifically, the storage device 7 includes at least two freezing bins 71, and the refrigeration structures of the freezing bins 71 are independent of each other, so that the refrigeration structure of any freezing bin 71 can be used independently. In this way, when any freezing bin 71 needs to be defrosted, it will not affect the temperature in the other freezing bins 71. In this way, the first container in the freezing bin 71 that needs to be defrosted can be dispatched to the other freezing bin 71, so that the first container will not be affected by the defrosting operation and can always maintain the target temperature, thereby ensuring the stability of the quality control product / calibration product stored in the first container.

[0118] In some embodiments, the storage device 7 includes a timing module, which is used to record the interval time from the last defrosting of the freezer bin 71. The controller is used to control the freezer bin 71 that needs to defrost to perform a defrosting operation after the interval time reaches a preset threshold and all first containers in the freezer bin 71 are taken out.

[0119] The intervals for the defrosting operation of the freezer bin 71 are different, and the degree of frost inside is also different. Therefore, the timing module can automatically record the interval from the last defrosting of the freezer bin 71, so that the controller 8 can automatically control the freezer bin 71 according to the interval to call out the first container in the freezer bin 71 when the defrosting operation is required, and perform the corresponding defrosting operation, which has a higher degree of automation and can effectively save energy while clearing the frost in time.

[0120] In other embodiments, the timing module is used to record the cumulative opening time of the freezer bin 71 since the last defrost, and the controller 8 is used to control the freezer bin 71 that needs to be defrosted to perform a defrost operation after the cumulative opening time reaches a preset threshold and all first containers in the freezer bin 71 are taken out.

[0121] The accumulated opening time of the freezer bin 71 is different, and the degree of frost inside will also be different. Therefore, the accumulated opening time of the freezer bin 71 can be automatically recorded through the timing module, so that the controller 8 can automatically control the freezer bin 71 according to the accumulated opening time to call out the first container in the freezer bin 71 when defrosting operation is required, and perform corresponding defrosting operation. While ensuring that frost can be handled in time, frequent defrosting treatment is avoided, thereby protecting the refrigeration structure and heating structure of the freezer bin 71.

[0122] An embodiment of the present application provides a storage device 7, which includes a freezing chamber 71, a heat insulation component and a controller 8.

[0123] The freezing chamber 71 is used to store the first container containing the quality control product / calibration product and provide a sub-zero refrigeration environment. The heat insulation component has a first state and a second state. In the first state, the heat insulation component is arranged around the first container to insulate the first container from the inner wall of the freezing chamber. In the second state, the heat insulation component is removed from around the first container to release the heat insulation between the first container and the inner wall of the freezing chamber.

[0124] The controller 8 is used to control the freezing of the freezer compartment and control the insulation component to be in the second state during the refrigeration process of the freezer compartment 71. It is also used to control the insulation component to switch to the first state and control the freezer compartment 71 that needs to be defrosted to perform the defrosting operation when the freezer compartment 71 needs to be defrosted.

[0125] In this way, when the freezing bin 71 needs to be defrosted, the controller 8 only needs to control the insulation component to be in the first state, and cover the insulation component around the first container. When the freezing bin 71 ends the defrosting operation and is in the refrigeration process, the controller 8 controls the insulation component to be in the second state, and removes the insulation component. There is no need to set up an additional scheduling mechanism. The first containers can be transferred out of the freezing bin 71 that needs to be defrosted one by one, and after the defrosting is completed, they can be transferred into the freezing bin 71 one by one. This is more convenient and quick, and is conducive to user operation.

[0126] An embodiment of the present application also provides an analysis system, which includes an analyzer, a conveying mechanism, and a storage device 7 as described in any of the above embodiments, wherein the conveying mechanism is used to transfer the first container in the freezing chamber 71 to the analyzer for quality control / calibration testing.

[0127] The analyzer includes a sample supply mechanism 1, a reagent supply mechanism 2, a sample dispensing mechanism 3, a reagent dispensing mechanism 4 and a detection device.

[0128] The sample supply mechanism 1 is used to carry a sample container containing a sample to be measured.

[0129] The reagent supply mechanism 2 is used to carry a reagent container containing a reagent.

[0130] The sample dispensing mechanism 3 is used to add the sample into the reaction container.

[0131] The reagent dispensing mechanism 4 is used to add the reagent in the reagent chamber into the corresponding reaction container.

[0132] The detection device is used to detect the reaction liquid containing the sample and the reagent in the reaction container to obtain the sample detection result.

[0133] In this embodiment, the analyzer and the storage device are provided separately and are cascaded to form an analysis system.

[0134] In some embodiments, the analyzer further includes a first dispensing mechanism, which is used to add the quality control product / calibration product in the first container retrieved from the freezing chamber 71 to the corresponding reaction container. The detection device is also used to detect the mixed solution containing the quality control product / calibration product and the reagent in the reaction container to obtain the quality control / calibration detection result.

[0135] In some embodiments, the first dispensing mechanism and the sample dispensing mechanism 3 are the same mechanism. In this embodiment, the sample dispensing mechanism 3 is used to dispense the quality control material / calibration material in the first container in addition to dispensing the sample. In other embodiments, the first dispensing mechanism and the sample dispensing mechanism 3 are two independent and different mechanisms.

[0136] like Figure 4 As shown, the embodiment of the present application also provides a defrosting method for a sample analyzer, comprising:

[0137] S1: Obtaining defrost demand information of the freezing chamber, and judging whether the freezing chamber needs to be defrosted based on the defrost demand information;

[0138] S2: Obtaining occupancy information of the cold storage bin, and determining whether the cold storage bin is empty based on the occupancy information;

[0139] S3: If it is determined that the freezing chamber needs to be defrosted and the freezing chamber is empty, the freezing chamber is controlled to perform a defrosting operation.

[0140] Among them, Figure 5 As shown, step S1 includes:

[0141] S11: Record the cumulative opening time of the freezer compartment since the last defrost;

[0142] S12: Compare the accumulated cover opening time with a preset threshold;

[0143] S13: If the accumulated opening time is not less than a preset threshold, it is determined that the freezer compartment needs to be defrosted.

[0144] The defrosting method also includes: if it is determined based on the occupancy information that the freezing bin is not empty, the control scheduling mechanism will call out all the containers in the freezing bin that need to be defrosted and are partially empty.

[0145] Specifically, Figure 6 As shown, the embodiment of the present application also provides a method for starting a defrost operation of a freezing chamber of a sample analyzer. After the freezing chamber is loaded, the method for starting a defrost operation includes:

[0146] S10: Determine whether the freezer compartment is empty. That is, determine whether the first container is stored in the freezer compartment. If the freezer compartment is empty, mark the freezer compartment as a defrostable state. If the freezer compartment is not empty, proceed to S20.

[0147] S20: Waiting for the first container calling test to be performed, that is, waiting for the controller to control the dispatching mechanism to call out the first container in the freezing chamber.

[0148] S30: Record the opening time t of the freezer compartment when executing the call test, and add the current opening time t to the total accumulated opening time T of the freezer compartment.

[0149] S40: Determine whether the accumulated opening time T of the freezer compartment is greater than the defrost time threshold. If not, there is no need to perform defrost operation temporarily. If greater than the defrost time threshold, proceed to S50.

[0150] S50: Determine whether the freezer compartment is in a defrostable state. If the freezer compartment is in a defrostable state, the defrosting operation can be started when the time set by the customer is reached. If the freezer compartment is in a non-defrostable state, the process proceeds to S60.

[0151] S60: Determine whether the position of the first container can be arranged between the freezing bins so that the freezing bin can achieve a defrosting state. If it can be achieved, the defrosting operation can also be started when the customer set time is reached. If it cannot be achieved, it will go to S20 and wait for the first container call test to be executed again.

[0152] S70: After the defrosting of the freezing chamber is completed, it is determined whether it is necessary to perform the defrosting operation of another freezing chamber. If it is necessary, the process proceeds to S60 to determine whether the position of the first container can be adjusted between the freezing chambers so that the freezing chamber can be defrosted. If it is not necessary, the process proceeds to S80.

[0153] S80: Waiting for the first container to be loaded, that is, waiting for the controller to control the dispatching mechanism to transfer the first container back to the freezing chamber where defrosting is completed.

[0154] In the description of the present application, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the embodiments of the present application. In the present application, the schematic representation of the above terms is not necessarily for the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine different embodiments or examples described in the present application and the features of different embodiments or examples without contradiction.

[0155] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A sample analyzer, It is characterized in that include: A sample supply mechanism, used for carrying a sample container containing a sample to be measured; A reagent supply mechanism, used for carrying a reagent container containing a reagent; A sample dispensing mechanism, used for adding the sample into a reaction container; A reagent dispensing mechanism, used for adding the reagent in the reagent chamber into the corresponding reaction container; A detection device, used for detecting the reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result; The storage device comprises at least one freezing chamber, wherein the freezing chamber is used to store the first container containing the quality control product / calibration product and provide a sub-zero refrigeration environment; A dispatching mechanism, used for transferring the first container into and / or out of the freezing warehouse; The controller is used to control the scheduling mechanism to call out all the first containers in the freezing bin that need to be defrosted, and control the freezing bin to perform a defrosting operation when the freezing bin storing the first container needs to be defrosted.

2. The sample analyzer according to claim 1, It is characterized in that The freezing warehouse comprises a warehouse body and a refrigeration structure, wherein the refrigeration structure is used to provide a refrigeration environment for the warehouse body, and the warehouse body is used to store the first container; The storage device comprises at least two freezing chambers, and the refrigeration structures of the freezing chambers are independent of each other, so that the refrigeration structure of any freezing chamber can be used independently.

3. The sample analyzer according to claim 1, It is characterized in that The freezing warehouse comprises a warehouse body, a refrigeration structure and a heating structure, wherein the refrigeration structure is used to provide a refrigeration environment for the warehouse body, and the warehouse body is used to store the first container; the controlling the freezing warehouse to perform a defrosting operation comprises: controlling the refrigeration structure to stop refrigeration, and controlling the heating structure to perform heating; or, The freezing warehouse includes a warehouse body and a refrigeration structure, wherein the refrigeration structure is used to provide a refrigeration environment for the warehouse body, and the warehouse body is used to store the first container; and controlling the freezing warehouse to perform a defrosting operation includes: controlling the refrigeration structure to stop refrigeration.

4. The sample analyzer according to claim 1, It is characterized in that The freezing chamber includes a semiconductor refrigeration chip, the sample analyzer includes a power supply circuit, the semiconductor refrigeration chip is connected to the power supply circuit, and the controller is used to control the direction of the voltage loaded on the semiconductor refrigeration chip by the power supply circuit, thereby controlling the semiconductor refrigeration chip to cool or heat the freezing chamber.

5. The sample analyzer according to claim 1, It is characterized in that The storage device includes at least two freezing bins, and the controller is used to: when one of the freezing bins storing the first container needs to be defrosted, control the scheduling mechanism to schedule at least part of the first container in the freezing bin that needs to be defrosted to other freezing bins, and control the freezing bin that needs to be defrosted to perform a defrosting operation.

6. The sample analyzer according to claim 1, It is characterized in that The storage device also includes a heat preservation bin, and the controller is used to control the scheduling mechanism to schedule at least part of the first container in the freezer bin to the heat preservation bin and control the freezer bin to perform a defrosting operation when the freezer bin storing the first container needs to defrost.

7. The sample analyzer according to claim 1, It is characterized in that The sample analyzer includes a first dispensing mechanism. The controller is used to control the scheduling mechanism to schedule at least part of the first container in the freezing bin that needs to be defrosted to the liquid aspiration position of the first dispensing mechanism of the sample analyzer when the freezing bin storing the first container needs to be defrosted. The first dispensing mechanism is used to add the quality control product / calibration product in the first container scheduled to the liquid aspiration position to the corresponding reaction container to perform quality control / calibration testing.

8. The sample analyzer according to any one of claims 1 to 7, It is characterized in that The sample analyzer includes a timing module; The timing module is used to record the interval time from the last defrost of the freezing bin, and the controller is used to control the scheduling mechanism to call out all the first containers in the freezing bin that need to be defrosted, and then control the freezing bin that needs to be defrosted to perform a defrost operation when the interval time reaches a preset threshold; or, the timing module is used to record the cumulative opening time of the freezing bin since the last defrost, and the controller is used to control the scheduling mechanism to call out all the first containers in the freezing bin that need to be defrosted, and then control the freezing bin that needs to be defrosted to perform a defrost operation when the cumulative opening time reaches a preset threshold.

9. The sample analyzer according to claim 8, It is characterized in that The sample analyzer includes a detection module, which is used to detect environmental parameters outside the freezing chamber and obtain environmental parameter information, wherein the environmental parameters include at least one of temperature and humidity, and the controller is used to adjust the preset threshold according to the environmental parameter information.

10. The sample analyzer according to any one of claims 1 to 7, It is characterized in that The sample analyzer includes a detection component, which is used to detect frost information in the freezing bin. The controller is used to control the scheduling mechanism to call out all the first containers in the freezing bin that need to be defrosted when the frost information reaches a preset condition, and then control the freezing bin to perform a defrosting operation.

11. A sample analyzer, It is characterized in that include: A sample supply mechanism, used for carrying a sample container containing a sample to be measured; A reagent supply mechanism, used for carrying a reagent container containing a reagent; A sample dispensing mechanism, used for adding the sample into a reaction container; A reagent dispensing mechanism, used for adding the reagent in the reagent chamber into the corresponding reaction container; A detection device, used for detecting the reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result; A storage device, comprising a freezing chamber and a heat insulation component, wherein the freezing chamber is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment; the heat insulation component has a first state and a second state, wherein in the first state, the heat insulation component is covered around the first container to insulate the first container from the inner wall of the freezing chamber; in the second state, the heat insulation component is removed from around the first container to release the heat insulation between the first container and the inner wall of the freezing chamber; The controller is used to control the freezing of the freezer compartment and control the thermal insulation component to be in the second state during the refrigeration process of the freezer compartment; it is also used to control the thermal insulation component to switch to the first state and control the freezer compartment that needs to be defrosted to perform a defrosting operation when the freezer compartment needs to be defrosted.

12. A storage device, It is characterized in that include: At least one freezing chamber, the freezing chamber is used to store the first container containing the quality control product / calibration product and provide a sub-zero refrigeration environment; The controller is used for controlling the freezing bin that needs to be defrosted to perform a defrosting operation when the freezing bin storing the first container needs to be defrosted and all the first containers in the freezing bin are taken out.

13. The storage device according to claim 12, It is characterized in that The freezing warehouse comprises a warehouse body and a refrigeration structure, wherein the refrigeration structure is used to provide a refrigeration environment for the warehouse body, and the warehouse body is used to store the first container; The storage device comprises at least two freezing chambers, and the refrigeration structures of the freezing chambers are independent of each other, so that the refrigeration structure of any freezing chamber can be used independently.

14. The storage device according to claim 12 or 13, It is characterized in that The storage device includes a timing module; The timing module is used to record the interval time from the last defrost of the freezing bin, and the controller is used to control the freezing bin that needs to be defrosted to perform a defrost operation after the interval time reaches a preset threshold and all the first containers in the freezing bin are taken out; or, the timing module is used to record the cumulative opening time of the freezing bin since the last defrost, and the controller is used to control the freezing bin that needs to be defrosted to perform a defrost operation after the cumulative opening time reaches a preset threshold and all the first containers in the freezing bin are taken out.

15. A storage device, It is characterized in that include: A freezing chamber and a heat insulation assembly, wherein the freezing chamber is used to store a first container containing a quality control product / calibration product and provide a sub-zero refrigeration environment; The heat insulation component has a first state and a second state. In the first state, the heat insulation component is disposed around the first container to insulate the first container from the inner wall of the freezing chamber. In the second state, the heat insulation component is removed from around the first container to release the heat insulation between the first container and the inner wall of the freezing chamber. The controller is used to control the freezing of the freezer compartment and control the thermal insulation component to be in the second state during the refrigeration process of the freezer compartment; it is also used to control the thermal insulation component to switch to the first state and control the freezer compartment that needs to be defrosted to perform a defrosting operation when the freezer compartment needs to be defrosted.

16. An analysis system, It is characterized in that comprising an analyzer, a conveying mechanism, and the storage device according to any one of claims 11 to 15, wherein the conveying mechanism is used to transfer the first container in the freezing chamber to the analyzer for quality control / calibration testing by the analyzer; Wherein, the analyzer comprises: A sample supply mechanism, used for carrying a sample container containing a sample to be measured; A reagent supply mechanism, used for carrying a reagent container containing a reagent; A sample dispensing mechanism, used for adding the sample into a reaction container; A reagent dispensing mechanism, used for adding the reagent in the reagent chamber into the corresponding reaction container; The detection device is used to detect the reaction solution containing the sample and the reagent in the reaction container to obtain the sample detection result.