Production and processing method of capsule type gene recombination superoxide dismutase

Abstract

The invention provides a production and processing method of capsule type gene recombination superoxide dismutase, and relates to the technical field of production and processing of superoxide dismutase, the production and processing method of capsule type gene recombination superoxide dismutase mainly comprises the following steps: S1, preparing capsule materials; gene recombination superoxide dismutase particles needing to be packaged are prepared, meanwhile, a proper amount of capsule shell materials are prepared, and the capsule shell materials are prepared to be large capsules and small capsules; s2, packaging capsule particles; taking out the gene recombination superoxide dismutase particles by a worker, and packaging the gene recombination superoxide dismutase particles into a small capsule shell to complete the preparation of the inner core component of the large capsule; according to the production and processing method provided by the invention, full-automatic unattended automatic production of capsules of a capsule-in-capsule structure by a production line is facilitated, and the phenomenon that liquid is splashed out in the process of putting small medicine capsule particles into a large capsule can be greatly avoided by utilizing the sequence of first feeding and then liquid injection.

Description

Technical Field

[0001] The present invention relates to the technical field of superoxide dismutase production and processing, and specifically to a production and processing method of capsule-type recombinant superoxide dismutase. Background Art

[0002] Capsules are a common pharmaceutical dosage form, which can be divided into two main types: hard capsules and soft capsules. Hard capsules are usually used to fill solid or powdered drugs, while soft capsules are mainly used to fill oils or other liquid drugs. The advantages of capsules include smooth appearance, easy to take, able to mask the bad smell of drugs, improve drug stability, etc.

[0003] Superoxide dismutase (SOD) is an important antioxidant enzyme, widely distributed in various organisms such as animals, plants, and microorganisms. SOD has special physiological activities and is the primary substance for scavenging free radicals in organisms. SOD can counteract and block the damage caused by oxygen free radicals to cells, and timely repair damaged cells and recover the cell damage caused by free radicals. Genetic recombination technology can be used to produce highly active SOD enzymes. By introducing the SOD gene into other organisms such as bacteria, yeast, plant, or animal cells, the high-efficiency expression of SOD enzymes can be achieved. The SOD enzymes produced in this way have higher activity and stability and can be used in the fields of medicine, health care, cosmetics, etc.

[0004] Currently, there are also related patented technologies for the production and processing of capsule-type recombinant superoxide dismutase. For example, Patent No. 202411337416.2 discloses a method for making a compound enzyme drug for treating inflammatory enteritis, and discloses the following steps: mold circulating rotation, empty capsule supply, supply automatic commutation, capsule body and cap separation, filling the compound enzyme into the capsule body, capsule body and cap fastening, finished product collection, and finished product packaging. The present invention adopts fully automated unmanned batch production and processing for the production process of the compound enzyme drug, with high production efficiency, no need for personnel intervention and contact during the production process, hygienic and clean in the hygiene process of the compound enzyme, the drug is not easily contaminated and has a high qualified rate. For the capsule shells used as the carrier of the compound enzyme, the present invention uses a machine to fully automatically sort and reverse the empty capsule shells, automatically organize and separate each empty capsule shell, and automatically quantitatively fill the separated capsule bodies with compound enzyme powder particles, with fully automated unmanned production and manufacturing, high production efficiency, and fast production speed.

[0005] Although the above patent discloses a production method for superoxide dismutase capsules, it still needs improvement. For some specific treatment requirements, it is not allowed for capsule drugs and different active ingredients to be released at different time points or rates to meet specific treatment needs; or in the case where a patient needs to use multiple drug effects in combination, it is rather cumbersome to take multiple capsules or tablets. Therefore, a production and processing method for a capsule-type recombinant superoxide dismutase with a structure of capsule within capsule is needed. Summary of the Invention

[0006] Aiming at the problems in the prior art, the purpose of the present invention is to provide a production and processing method for a capsule-type recombinant superoxide dismutase, to solve the technical problems described in the above background art: Although the above patent discloses a production method for superoxide dismutase capsules, it still needs improvement. For some specific treatment requirements, it is not allowed for capsule drugs and different active ingredients to be released at different time points or rates to meet specific treatment needs; or in the case where a patient needs to use multiple drug effects in combination, it is rather cumbersome to take multiple capsules or tablets. Therefore, a production and processing method for a capsule-type recombinant superoxide dismutase with a structure of capsule within capsule is needed.

[0007] The technical problems to be solved by the present invention are achieved by adopting the following technical solutions: A production and processing method for a capsule-type recombinant superoxide dismutase, the production and processing method for this capsule-type recombinant superoxide dismutase mainly includes the following steps:

[0008] S1: Preparation of capsule materials; Prepare the recombinant superoxide dismutase particles to be encapsulated, and at the same time prepare an appropriate amount of capsule shell materials. Two types of capsule shell materials are prepared, namely large capsules and small capsules;

[0009] S2: Encapsulation of capsule particles; The staff takes out the recombinant superoxide dismutase particles and encapsulates the recombinant superoxide dismutase particles inside the small capsule shell to complete the production of the inner core components of the large capsule;

[0010] S3: Separation of large capsules; Use an automated production line to separate the large capsule cap and the large capsule body of the large capsule shell, and the separated large capsule shells are conveyed in a staggered manner;

[0011] S4: Filling of capsule particles; During the staggered conveyance of the large capsules separated in step S3, the encapsulated capsule particles in step S2 are put into the large capsule bodies separated in a staggered manner as the inner cores inside the large capsule bodies. After the capsule particles are put into the large capsule bodies, there is still enough space to inject a small amount of liquid;

[0012] S5: Liquid filling; The large capsule bodies with capsule particles placed in step S4 continue to be conveyed in a staggered manner on the automated production line. During the staggered conveyance process, a small amount of liquid is injected into the large capsule bodies with capsule particles. Ensure that each large capsule body is filled with capsule particles and liquid;

[0013] S6: Capsule closing station; The large capsule bodies and large capsule caps separated in a staggered manner are closed to completely enclose the encapsulated capsule particles and liquid in the large capsule, forming a large capsule with an inner capsule structure;

[0014] S7: Capsule collection; The large capsules after closing are collected and sent to the later process for packaging.

[0015] As a preferred technical solution of the present invention, the above-mentioned steps S4 - S7 are mainly completed by an automated production line. The automated production line includes an intermittent turntable that rotates intermittently in a cycle, and a capsule feeding mechanism, a particle feeding mechanism, an oil injection mechanism, a capsule closing mechanism, and a collection mechanism that are arranged at equal intervals on the outer peripheral surface of the intermittent turntable. Among them, the capsule feeding mechanism is used to feed large capsules. The middle part of the intermittent turntable is fixed to the top of the central shaft. The bottom end of the central shaft is rotatably connected to the top of the fixed base. The fixed base is fixed to the ground. A servo motor is fixedly installed at the top of the fixed base. The output shaft of the servo motor extends upward. A driving gear is installed at the top of the output shaft of the servo motor. A driven gear is fixedly installed on the outer peripheral surface of the central shaft. The driven gear is meshed and connected with the driving gear;

[0016] A second-order turntable is arranged at the bottom of the intermittent turntable. A connecting bracket is fixedly connected between the second-order turntable and the intermittent turntable. The second-order turntable rotates synchronously with the intermittent turntable through the connecting bracket. Upper brackets are arranged at equal intervals in a circumferential manner on the outer peripheral surface of the intermittent turntable. Through capsule holes are opened on the surface of the upper brackets. Bracket supports are arranged at equal intervals in a circumferential manner on the top of the second-order turntable. A lower bracket is installed on the surface of each bracket support. Capsule holes corresponding to the surface of the upper bracket are also opened on the top surface of the lower bracket.

[0017] As a preferred technical solution of the present invention, a bottom support plate is arranged at the bottom of the second-order turntable. The bottom support plate is of a disc structure. A walking ramp with undulations is arranged on the top surface of the bottom support plate. The top surface of the walking ramp rises from the bottom of the oil injection mechanism and then descends to the middle position between the capsule closing mechanism and the particle feeding mechanism. The top surface of the walking ramp located between the oil injection mechanism and the particle feeding mechanism remains horizontally level. A ramp support cylinder is arranged at the bottom of the bottom support plate. The ramp support cylinder is fixed to the top of the fixed base.

[0018] As a preferred technical solution of the present invention, each of the lower brackets includes a spring base provided on the top surface of the second-order turntable. The bottom of the bracket support is provided with a lifting shaft rod passing through the surface of the second-order turntable and the inside of the spring base. The lifting shaft rod extends to the bottom of the second-order turntable. The lifting shaft rod is axially slidably connected to the second-order turntable and the spring base. The bottom of the lifting shaft rod extending to the bottom of the second-order turntable is provided with traveling rollers. A support spring is connected between the bottom of the lifting shaft rod and the spring base. The traveling rollers are in rolling connection with the top surface of the traveling slope.

[0019] As a preferred technical solution of the present invention, a special-shaped wheel is provided between the bottom of the intermittent turntable and the second-order turntable. The top surface of the special-shaped wheel is in clearance fit or sliding connection with the bottom surface of the intermittent turntable. An activity shaft rod is axially slidably connected to the surface of the bracket support. The lower bracket is fixed to the outermost end of the activity shaft rod. The other end of the activity shaft rod is provided with a roller assembly. The roller assembly is in rolling connection with the surface of the special-shaped wheel. A bracket spring is provided between the top end of the activity shaft rod equipped with the roller assembly and the surface of the bracket support.

[0020] As a preferred technical solution of the present invention, the roller assembly includes a steel ball sliding sleeve fixed to the top end of the activity shaft rod. Rolling steel balls are rollably connected inside the steel ball sliding sleeve. The rolling steel balls are in rolling contact with the surface of the special-shaped wheel.

[0021] As a preferred technical solution of the present invention, the particle feeding mechanism includes a cylinder support fixed to the top end of the fixed base. A first pusher cylinder is fixedly installed at the top end of the cylinder support. A support arm is fixedly installed at the top end of the cylinder support. A medicine particle hopper is fixedly installed at the top end of the support arm. A support plate sleeve is provided at the bottom of the medicine particle hopper. A long block-shaped piercing support plate is slidably connected to the middle of the support plate sleeve. A plurality of parallel capsule particle flow cavities are equidistantly opened inside the piercing support plate. The top ends of the capsule particle flow cavities communicate with the inside of the medicine particle hopper. A push rod is provided on the front end face of the piercing support plate;

[0022] A sorting base is provided on the front side of the cylinder support. A plurality of forklift chutes are equidistantly provided on the surface of the sorting base. A sorting forklift is slidably connected to each forklift chute on the surface of the sorting base. The rear end of the sorting forklift is fixed to the top end of the piston rod of the first pusher cylinder;

[0023] A first pull rope buckle is provided at the top end of the sorting forklift. A first pull rope buckle is also provided on the surface of the piercing support plate. A first fixed pulley is rotatably connected to the middle of the support arm. A second fixed pulley is rotatably connected to the top end of the support arm. A first pull rope is connected to the first pull rope buckle on the surface of the piercing support plate. The other end of the first pull rope passes through the second fixed pulley and the first fixed pulley in sequence and is connected to the first pull rope buckle at the top end of the sorting forklift.

[0024] As a preferred technical solution of the present invention, the capsule feeding mechanism and the granule feeding mechanism adopt the same structural settings in the way of feeding capsules. The size of the capsule particle flow cavity and the forklift chute in the middle of the capsule feeding mechanism is slightly larger than that of the capsule particle flow cavity and the forklift chute in the middle of the granule feeding mechanism;

[0025] The capsule feeding mechanism further includes a guiding slide rod arranged under the sorting base. A suction base is slidably connected to the middle of the guiding slide rod. A suction nozzle sleeve is arranged on the surface of the suction base. A through round hole is opened in the middle of the suction nozzle sleeve. A suction nozzle rod body is axially slidably connected in the round hole of the suction nozzle sleeve. A negative pressure suction nozzle is arranged at the top end of the suction nozzle rod body. A compression spring is installed on the outer wall of the suction nozzle rod body. An air inlet interface is arranged at the bottom of the suction nozzle rod body.

[0026] A fixed pulley three is arranged on the surface of the sorting base. A second rope buckle is arranged at the bottom of the sorting forklift. A second rope buckle is fixed to the top end of the suction base. A second pull rope is connected to the second rope buckle at the bottom of the sorting forklift. The other end of the second pull rope passes through the fixed pulley three and is fixedly connected to the second rope buckle at the top end of the suction base.

[0027] As a preferred technical solution of the present invention, the capsule combining mechanism includes a cylinder support plate fixed to the top end of the fixed base. A double piston cylinder is fixedly installed on the surface of the cylinder support plate. A piston rod extends from each end of the double piston cylinder. A capsule pushing rod is arranged at the top end of each piston rod of the double piston cylinder.

[0028] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0029] First, a method for producing and processing a capsule-type recombinant superoxide dismutase provided by the present invention can facilitate the fully automatic and unattended production of capsules with a capsule-in-capsule structure on a production line. By using the sequence of feeding materials first and then injecting liquid, the phenomenon of liquid splashing inside the large capsule during the process of putting small medicine grain capsules (granules) can be greatly avoided.

[0030] Second, the automatic production line provided by the present invention can realize the fully automatic and unattended production and processing process of capsules with a capsule-in-capsule structure, and the production and processing process can effectively reduce the phenomenon that the position of the large capsule placed in the capsule hole of the lower bracket is inaccurate.

[0031] III. The capsule feeding mechanism provided by the present invention enables the large capsule shell to be initially fed into the capsule hole on the surface of the upper bracket in the forklift chute. When the ejector rod and the negative pressure suction nozzle move up and down synchronously and extend into the top of the upper bracket and the bottom of the lower bracket after mold closing, when the large capsule shell is pushed downward from the forklift chute by the ejector rod and the capsule has not fallen into the capsule hole at the top of the upper bracket, the air duct interface at the bottom of the lower bracket is connected through the negative pressure suction nozzle. At this time, an air pressure that adsorbs into the capsule hole will be generated in the capsule hole at the top of the upper bracket, so as to push the large capsule shell into the capsule hole at the top of the upper bracket more quickly. The large capsule shell pushed downward by the ejector rod can fall more precisely into the capsule hole at the top of the upper bracket by using the pushing force of the air pressure.

[0032] IV. At the same time, the large capsule shell that falls into the capsule hole at the top of the upper bracket uses the air pressure at the bottom of the lower bracket to automatically separate the capsule cap and the capsule body of the large capsule shell by means of the step contour in the capsule hole at the top of the upper bracket. The separated capsule cap stays in the capsule hole at the top of the upper bracket, and the separated capsule body stays in the capsule hole of the lower bracket, realizing the automatic separation of the large capsule body and the cap.

[0033] V. In the present invention, the top surface of the walking slope rises from the bottom of the self-lubricating mechanism and descends to the middle position between the capsule combining mechanism and the granule feeding mechanism, so that the separated large capsule shell moves to the middle position between the capsule combining mechanism and the granule feeding mechanism through the lower bracket and the upper bracket. The lower bracket sinks a certain distance to realize the vertical separation of the upper bracket and the lower bracket. At the same time, with the design of the special-shaped wheel, the separated lower bracket automatically extends outwards, so as to realize the left-right staggered separation of the upper bracket and the lower bracket in space. The spatial staggered separation formed by the outward extension of the lower bracket can make the granule feeding mechanism and the lubricating mechanism more smoothly during the feeding process, not easily form movement interference and structural interference, and is beneficial to improving the feeding accuracy.

[0034] VI. In the present invention, the roller assembly rolls in all directions on the outer circular surface of the special-shaped wheel, which can effectively reduce the resistance when the lower bracket extends outwards, so that the lower bracket can smoothly extend, retract, rise or fall during any process of vertical separation and spatial staggered separation, effectively improving the movement stability of the lower bracket. Moreover, the roller assembly has a simple structure and is convenient for later maintenance.

[0035] VII. Through the structural design of the walking slope and the special-shaped wheel, the present invention does not require a large number of sensors and power components, and can achieve absolute action response when each lower bracket moves to the position below the corresponding mechanism. The lower bracket has sensitive actions and stable work, is suitable for long-term high-speed rotation production and processing, and can effectively improve the production and processing efficiency of capsules. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] The present invention will be further described below with reference to the drawings and embodiments.

[0037] Figure 1 This is a flowchart of the steps for the production and processing method of the capsule-type recombinant superoxide dismutase of the present invention;

[0038] Figure 2 This is a top view structural schematic diagram of the automated production line of the present invention;

[0039] Figure 3 This is a top view structural schematic diagram of the special-shaped wheel, connecting bracket, bracket support, upper bracket, and lower bracket of the present invention;

[0040] Figure 4 This is a left view sectional structural schematic diagram of the particle feeding mechanism of the present invention;

[0041] Figure 5 This is a left view sectional structural schematic diagram of the capsule feeding mechanism of the present invention;

[0042] Figure 6 This is an attached Figure 5 partial enlarged view of part A in the specification of the present invention;

[0043] Figure 7 This is a left view sectional structural schematic diagram of the negative pressure suction nozzle, air duct interface, suction nozzle rod body, and air inlet interface of the present invention;

[0044] Figure 8 This is a front view structural schematic diagram of the liquid storage hopper, liquid infusion tube, and oil injection needle base of the present invention;

[0045] Figure 9 This is an attached Figure 5 partial enlarged view of part B in the specification of the present invention;

[0046] Figure 10 This is a structural schematic diagram of the large capsule, capsule particles, and the liquid inside the large capsule of the present invention;

[0047] In the figure: capsule throwing mechanism 1, granule throwing mechanism 2, granule hopper 201, support arm 202, cylinder bracket 203, first pusher cylinder 204, first fixed pulley 205, sorting base 206, ejector rod 207, support plate 208, support plate sleeve 209, capsule and granule flow cavity 210, second fixed pulley 211, first rope buckle 212, first rope 213, sorting forklift 214, oil injection mechanism 3, second rope buckle 301, second rope 302, suction base 304, guiding slide bar 305, compression spring 306, negative pressure suction nozzle 307, airway interface 308, suction nozzle rod body 309, intake interface 310, liquid storage hopper 311, infusion tube 312, oil injection needle base 313, oil injection needle 314, capsule closing mechanism 4, cylinder support plate 401, double piston cylinder 402, capsule pushing rod 403, collection mechanism 5, intermittent turntable 6, central shaft 7, capsule hole 8, upper bracket 9, lower bracket 10, bracket support 11, movable shaft rod 12, bracket spring 13, roller assembly 14, steel ball sleeve 1401, rolling steel ball 1402, special-shaped wheel 15, feeding motor 16, special-shaped wheel support cylinder 17, walking slope 18, bottom support plate 19, driving gear 20, driven gear 21, connecting block 22, servo motor 23, feeding swing rod 24, fixed base 25, spring base 26, support spring 27, lifting shaft rod 28, walking roller 29, connecting bracket 30, slope support cylinder 31, second-order turntable 32. Detailed implementation mode

[0048] In order to make the technical means, creative features, achieved purposes and functions of the present invention easy to understand, the present invention will be further described below with reference to specific illustrations. It should be noted that, without conflict, the embodiments in this application and the features in the embodiments can be combined with each other.

[0049] Embodiment 1

[0050] Please refer to Figure 1 , which is a schematic diagram of the overall structure of a production and processing method of capsule-type recombinant superoxide dismutase;

[0051] A production and processing method of capsule-type recombinant superoxide dismutase mainly includes the following steps:

[0052] S1: Preparation of capsule materials; Prepare the recombinant superoxide dismutase particles to be encapsulated, and at the same time prepare an appropriate amount of capsule shell materials. Two types of capsule shell materials are prepared, namely large capsules and small capsules;

[0053] S2: Encapsulation of capsule particles; The staff takes out the recombinant superoxide dismutase particles and encapsulates the recombinant superoxide dismutase particles into the small capsule shell to complete the production of the inner core components of the large capsule;

[0054] S3: Separation of large capsules; The large capsule cap and the large capsule body of the large capsule shell are separated by an automated production line, and the separated large capsule shells are conveyed in a staggered manner.

[0055] S4: Filling capsule granules; During the staggered conveyance of the large capsules separated in step S3, the capsule granules encapsulated in step S2 are put into the separated large capsule bodies as the inner cores inside the large capsule bodies. After the capsule granules are put into the large capsule bodies, there is still enough space to inject a small amount of liquid.

[0056] S5: Liquid filling; The large capsule bodies filled with capsule granules in step S4 continue to be conveyed in a staggered manner on the automated production line. During the staggered conveyance, a small amount of liquid is injected into the large capsule bodies filled with capsule granules. Ensure that each large capsule body is filled with capsule granules and liquid. Among them, the liquid can be water, buffer solution, vegetable oil, etc. It can also be some oily drugs, semi-solid or liquid drugs, or suspensions of drugs, etc. Specifically, it needs to be selected according to different enzyme characteristics, drug release characteristics, bioavailability and other factors, but it must be ensured that these liquids will not have adverse reactions with the capsule shell. The specific type and properties of the liquid need to be determined according to the specific situation of the drug.

[0057] S6: Capsule closing station; The separated large capsule bodies and large capsule caps are closed to completely enclose the encapsulated capsule granules and liquid in the large capsule, forming a large capsule with a structure of capsule within capsule.

[0058] S7: Capsule collection; The large capsules after closing are collected and sent to the later process for packaging.

[0059] Specifically, in this embodiment, a method for producing and processing a capsule-type recombinant superoxide dismutase provided by the present invention can facilitate the fully automatic and unattended production of capsules with a structure of capsule within capsule on the production line. Using the sequence of feeding first and then injecting liquid can greatly avoid the phenomenon of liquid splashing inside the large capsule during the process of putting small medicine particles (capsule granules).

[0060] Specifically, in this embodiment, the automated production line provided by the present invention can achieve fully automatic and unattended automation to complete the production and processing process of capsules with a structure of capsule within capsule, and the production and processing process can effectively reduce the phenomenon that the position of the large capsule put into the capsule hole 8 of the lower bracket 10 is inaccurate.

[0061] The above-described steps S4 - S7 are mainly completed by an automated production line. The automated production line includes an intermittent turntable 6 that rotates in a cyclic intermittent manner, and a capsule feeding mechanism 1, a granule feeding mechanism 2, an oil injection mechanism 3, a capsule closing mechanism 4, and a collection mechanism 5 that are arranged at equal intervals around the outer circumferential surface of the intermittent turntable 6. Among them, the capsule feeding mechanism 1 is used to feed large capsules. The middle part of the intermittent turntable 6 is fixed to the top end of a central shaft 7, and the bottom end of the central shaft 7 is rotatably connected to the top end of a fixed base 25. The fixed base 25 is fixed to the ground, and a servo motor 23 is fixedly installed at the top end of the fixed base 25. The servo motor 23 extends upward with an output shaft, and a driving gear 20 is installed at the top end of the output shaft of the servo motor 23. A driven gear 21 is fixedly installed on the outer circumferential surface of the central shaft 7, and the driven gear 21 is meshed and connected with the driving gear 20;

[0062] A second-order turntable 32 is arranged at the bottom of the intermittent turntable 6. A connecting bracket 30 is fixedly connected between the second-order turntable 32 and the intermittent turntable 6. The second-order turntable 32 rotates synchronously with the intermittent turntable 6 through the connecting bracket 30. Upper brackets 9 are arranged at equal intervals in a circumferential manner on the outer circumferential surface of the intermittent turntable 6. Through holes for capsules 8 are provided on the surfaces of the upper brackets 9. Bracket supports 11 are arranged at equal intervals in a circumferential manner at the top end of the second-order turntable 32. A lower bracket 10 is installed on the surface of each bracket support 11, and through holes for capsules 8 corresponding to the surfaces of the upper brackets 9 are also provided on the top surface of the lower bracket 10.

[0063] Specifically, in this embodiment, the automated production line provided by the present invention adopts the form of the upper brackets 9 and the lower brackets 10 being separated up and down and staggered left and right to realize the fast automated capsule separation and closing process. By being separated up and down, the large capsule caps and large capsule bodies in the upper brackets 9 and the lower brackets 10 are separated up and down. Through being staggered left and right, the capsule feeding mechanism 1 and the oil injection mechanism 3 can first feed small medicine granules into the separated large capsule bodies and then inject liquid. The feeding process is smoother, and it is not easy to form movement interference and structural interference. The outward extension of the lower brackets 10 can reduce the influence and interference of the structure on the feeding process, and it is more convenient for the capsule feeding mechanism 1 and the oil injection mechanism 3 to feed or inject into each large capsule body on the surface of the lower brackets 10, thereby being more convenient to improve the feeding accuracy.

[0064] Embodiment 2

[0065] Please refer to Figures 2 - 10 , this embodiment has the same parts as the above Embodiment 1, and the same parts will not be elaborated in this embodiment. The specific differences are as follows:

[0066] The above-described steps S4 - S7 are mainly completed by an automated production line. The automated production line includes an intermittent turntable 6 that rotates in a cyclic intermittent manner, and a capsule feeding mechanism 1, a granule feeding mechanism 2, an oil injection mechanism 3, a capsule closing mechanism 4, and a collection mechanism 5 that are arranged at equal intervals around the outer circumferential surface of the intermittent turntable 6. Among them, the capsule feeding mechanism 1 is used to feed large capsules. The middle part of the intermittent turntable 6 is fixed to the top end of a central shaft 7, and the bottom end of the central shaft 7 is rotatably connected to the top end of a fixed base 25. The fixed base 25 is fixed to the ground. A servo motor 23 is fixedly installed at the top end of the fixed base 25. The servo motor 23 has an output shaft extending upward. A driving gear 20 is installed at the top end of the output shaft of the servo motor 23. A driven gear 21 is fixedly installed on the outer circumferential surface of the central shaft 7. The driven gear 21 is meshed and connected with the driving gear 20. By driving the driving gear 20 to rotate intermittently by the servo motor 23, and using the meshing rotation of the driving gear 20 and the driven gear 21, the intermittent rotation of the intermittent turntable 6 is driven, so as to drive each upper bracket 9 and the corresponding lower bracket 10 to rotate synchronously and intermittently to the positions of the capsule feeding mechanism 1, the granule feeding mechanism 2, the oil injection mechanism 3, the capsule closing mechanism 4, and the collection mechanism 5 and make a short stop.

[0067] A second-order turntable 32 is arranged at the bottom of the intermittent turntable 6. A connecting bracket 30 is fixedly connected between the second-order turntable 32 and the intermittent turntable 6. The second-order turntable 32 rotates synchronously with the intermittent turntable 6 through the connecting bracket 30 to realize the synchronous rotation of the second-order turntable 32 and the intermittent turntable 6. Upper brackets 9 are arranged at equal intervals in a circumferential manner on the outer circumferential surface of the intermittent turntable 6. Through holes for capsules 8 are formed on the surfaces of the upper brackets 9. Bracket supports 11 are arranged at equal intervals in a circumferential manner on the top end of the second-order turntable 32. A lower bracket 10 is installed on the surface of each bracket support 11. Through holes for capsules 8 corresponding to the surfaces of the upper brackets 9 are also formed on the top surface of the lower bracket 10, which is convenient for feeding large capsule shells into the through holes for capsules 8 of the lower bracket 10 and the upper bracket 9.

[0068] A bottom support plate 19 is arranged at the bottom of the second-order turntable 32. The bottom support plate 19 is of a disc structure. The top surface of the bottom support plate 19 is provided with a walking ramp 18 with undulating heights. The top surface of the walking ramp 18 at the bottom of the capsule closing mechanism 4, the collection mechanism 5, and the capsule feeding mechanism 1 is higher than the top surface of the walking ramp 18 at the bottom of the granule feeding mechanism 2 and the oil injection mechanism 3. The top surface of the walking ramp 18 starts to undulate upward from the bottom of the oil injection mechanism 3 to

[0069] descend at the intermediate position between the capsule closing mechanism 4 and the granule feeding mechanism 2. The top surface of the walking ramp 18 between the oil injection mechanism 3 and the granule feeding mechanism 2 remains horizontally level. A ramp support cylinder 31 is arranged at the bottom of the bottom support plate 19. The ramp support cylinder 31 is fixed to the top end of the fixed base 25. In the automated production line provided by the present invention, in the form of the upper bracket 9 and the lower bracket 10 being separated up and down and staggered left and right, during the fast automated capsule separation and closing process, the upper and lower separation is adopted to separate the large capsule caps and large capsule bodies in the upper bracket 9 and the lower bracket 10 up and down.

[0070] Specifically, in this embodiment, the present invention makes the top surface of the walking slope 18 undulate upward from the bottom of the self-lubricating mechanism 3 to the middle position between the capsule closing mechanism 4 and the granule feeding mechanism 2 and then descend, so that the separated large capsule shells are moved to the middle position between the capsule closing mechanism 4 and the granule feeding mechanism 2 through the lower bracket 10 and the upper bracket 9. The lower bracket 10 sinks a certain distance to realize the vertical separation of the upper bracket 9 and the lower bracket 10.

[0071] Each lower bracket 10 includes a spring base 26 arranged on the top surface of the second-order turntable 32. The bottom of the bracket support 11 is provided with a lifting shaft rod 28 passing through the surface of the second-order turntable 32 and the inside of the spring base 26. The lifting shaft rod 28 extends towards the bottom of the second-order turntable 32. The lifting shaft rod 28 is axially slidably connected to the second-order turntable 32 and the spring base 26. The bottom of the lifting shaft rod 28 extending towards the bottom of the second-order turntable 32 is provided with a walking roller 29. A support spring 27 is connected between the bottom of the lifting shaft rod 28 and the spring base 26. The walking roller 29 is in rolling connection with the top surface of the walking slope 18. By means of the support spring 27, each lower bracket 10 on the top surface of the second-order turntable 32 can be pushed to rise or fall according to the undulation of the top surface of the walking slope 18.

[0072] An irregular wheel 15 is arranged between the bottom of the intermittent turntable 6 and the second-order turntable 32. The bottom of the irregular wheel 15 is provided with an irregular wheel support cylinder 17. The irregular wheel support cylinder 17 is fixed to the top end of the bottom support plate 19. The irregular wheel 15 is connected to the bottom support plate 19 as an integral structure through the irregular wheel support cylinder 17. The top surface of the irregular wheel 15 is in clearance fit or sliding connection with the bottom surface of the intermittent turntable 6. An activity shaft rod 12 is axially slidably connected to the surface of the bracket support 11. The lower bracket 10 is fixed to the outermost end of the activity shaft rod 12. The other end of the activity shaft rod 12 is provided with a roller assembly 14. The roller assembly 14 is in rolling connection with the surface of the irregular wheel 15. A bracket spring 13 is arranged between the top end of the activity shaft rod 12 equipped with the roller assembly 14 and the surface of the bracket support 11;

[0073] The activity shaft rods 12 on each bracket support 11 are arranged perpendicular and staggered with the lifting shaft rods 28.

[0074] Specifically, in this embodiment, through the structural design of the walking slope 18 and the irregular wheel 15, the present invention does not need to use a large number of sensors and power components, and can achieve absolute action response when each lower bracket 10 moves to the position below the corresponding mechanism. The lower bracket 10 has sensitive actions and stable operation, is suitable for long-time high-speed rotation production and processing, and can effectively improve the production and processing efficiency of capsules.

[0075] Among them, the automated production line provided by the present invention adopts the form of upper bracket 9 and lower bracket 10 being separated up and down and staggered left and right to achieve a fast automated capsule splitting and combining process. By separating up and down, the large capsule caps and large capsule bodies in the upper bracket 9 and the lower bracket 10 are vertically separated. Through left and right staggering, the capsule feeding mechanism 1 and the oil injection mechanism 3 can first put small medicine particles into the separated large capsule bodies and then inject liquid. The feeding process is smoother, and it is not easy to form motion interference and structural interference. The outward extension of the lower bracket 10 can reduce the influence and interference of the structure on the feeding process, and it is more convenient for the capsule feeding mechanism 1 and the oil injection mechanism 3 to put or inject into each large capsule body on the surface of the lower bracket 10, thus facilitating the improvement of the feeding accuracy more easily.

[0076] In the present invention, the top surface of the walking slope 18 starts to rise from the bottom of the oil injection mechanism 3 and descends to the middle position between the capsule combining mechanism 4 and the particle feeding mechanism 2, so that the separated large capsule shells are moved to the middle position between the capsule combining mechanism 4 and the particle feeding mechanism 2 through the lower bracket 10 and the upper bracket 9. The lower bracket 10 sinks a certain distance to achieve the up and down separation of the upper bracket 9 and the lower bracket 10. At the same time, the design of the special-shaped wheel 15 is combined to make the separated lower bracket 10 automatically extend outwards, so as to achieve the left and right staggered separation of the upper bracket 9 and the lower bracket 10 in space. The spatial staggered separation formed by the outward extension of the lower bracket 10 can make the feeding processes of the particle feeding mechanism 2 and the oil injection mechanism 3 smoother, and it is not easy to form motion interference and structural interference, which is beneficial to improving the feeding accuracy.

[0077] The roller assembly 14 includes a steel ball sleeve 1401 fixed to the top end of the movable shaft rod 12. A rolling steel ball 1402 is rollingly connected inside the steel ball sleeve 1401, and the rolling steel ball 1402 is in rolling contact with the surface of the special-shaped wheel 15.

[0078] Specifically, in this embodiment, the present invention can effectively reduce the resistance when the lower bracket 10 extends outwards by the universal rolling of the roller assembly 14 on the outer circular surface of the special-shaped wheel 15, so that the lower bracket 10 can smoothly extend in, extend out, rise or fall during any process of up and down separation and spatial staggered separation, effectively improving the motion smoothness of the lower bracket 10. Moreover, the structure of the roller assembly 14 is simple and convenient for later maintenance.

[0079] The pellet feeding mechanism 2 includes a cylinder support 203 fixed to the top end of a fixed base 25. A first pellet pushing cylinder 204 is fixedly installed at the top end of the cylinder support 203. The first pellet pushing cylinder 204 extends forward with a piston rod. A support arm 202 is fixedly installed at the top end of the cylinder support 203. A medicine pellet hopper 201 is fixedly installed at the top end of the support arm 202. A support plate sleeve 209 is provided at the bottom of the medicine pellet hopper 201. A long block-shaped piercing support plate 208 is slidably connected to the middle of the support plate sleeve 209. A number of parallel capsule particle flow cavities 210 are equidistantly formed inside the piercing support plate 208. The top ends of the capsule particle flow cavities 210 communicate with the inside of the medicine pellet hopper 201. A push rod 207 is provided on the front end face of the piercing support plate 208;

[0080] A sorting base 206 is provided on the front side of the cylinder support 203. A number of forklift slides are equidistantly arranged on the surface of the sorting base 206. A sorting forklift 214 is slidably connected to each forklift slide on the surface of the sorting base 206. The rear end of the sorting forklift 214 is fixed to the top end of the piston rod of the first pellet pushing cylinder 204;

[0081] A first rope buckle 212 is provided at the top end of the sorting forklift 214. A first rope buckle 212 is also provided on the surface of the piercing support plate 208. A first fixed pulley 205 is rotatably connected to the middle of the support arm 202. A second fixed pulley 211 is rotatably connected to the top end of the support arm 202. A first rope 213 is connected to the first rope buckle 212 on the surface of the piercing support plate 208. The other end of the first rope 213 passes through the second fixed pulley 211 and the first fixed pulley 205 in sequence and is connected to the first rope buckle 212 at the top end of the sorting forklift 214.

[0082] Among them, the reciprocating pushing of the sorting forklift 214 drives the reciprocating lifting of the piercing support plate 208. The reciprocating lifting of the piercing support plate 208 in the medicine pellet hopper 201 will fill the capsule shells in the medicine pellet hopper 201 into each capsule particle flow cavity 210 inside the piercing support plate 208. The capsule shells enter the forklift slides of the lower sorting base 206 through the capsule particle flow cavities 210. The sorting forklift 21 reciprocates and slides in the forklift slides. The contour design at the front end of the sorting forklift 21 can make the capsule shells in different forward directions stay in the corresponding positions. With two pushes of the push rod 207, each capsule shell can be pushed into the capsule holes 8 at the top end of the lower upper bracket 9 in the same direction.

[0083] The capsule feeding mechanism 1 and the pellet feeding mechanism 2 adopt the same structural settings in the way of feeding capsules. The sizes of the capsule particle flow cavities 210 and the forklift slides in the middle of the capsule feeding mechanism 1 are slightly larger than those of the capsule particle flow cavities 210 and the forklift slides in the middle of the pellet feeding mechanism 2, because large capsule shells are put into the capsule feeding mechanism 1, while small medicine pellet capsules are put down into the pellet feeding mechanism 2.

[0084] The capsule feeding mechanism 1 further includes a guiding slide bar 305 disposed below the sorting base 206. A suction base 304 is slidably connected to the middle of the guiding slide bar 305. A nozzle sleeve 312 is provided on the surface of the suction base 304. A through circular hole is formed in the middle of the nozzle sleeve 312. A nozzle rod body 309 is axially slidably connected in the circular hole of the nozzle sleeve 312. A negative pressure nozzle 307 is provided at the top end of the nozzle rod body 309. A compression spring 306 is installed on the outer wall of the nozzle rod body 309. An air inlet interface 310 is provided at the bottom of the nozzle rod body 309; the air inlet interface 310 is communicated with an external negative pressure fan through a pipeline. Among them, the compression spring 306 can make the negative pressure nozzle 307 contact the airway interface 308 more closely during the initial contact process. At the same time, since the ejector rod 208 and the negative pressure nozzle 307 are driven by the first pull rope 213 and the second pull rope 302 to move up and down in linkage. The compression spring 306 can well make the negative pressure nozzle 307 adaptively elastically yield according to the ejector rod 208 during the contact process with the airway interface 308, so that both the ejector rod 208 and the negative pressure nozzle 307 can reach the expected moving positions.

[0085] Specifically, in this embodiment, the capsule feeding mechanism 1 provided by the present invention enables the large capsule shell to be initially placed into the capsule hole 8 on the surface of the upper bracket 9 in the forklift chute. The ejector rod 208 and the negative pressure nozzle 307 move up and down in synchronization and extend into the top end of the upper bracket 9 and the bottom end of the lower bracket 10 after mold closing. When the large capsule shell is pushed downward from the forklift chute by the ejector rod and the capsule has not yet fallen into the capsule hole 8 at the top end of the upper bracket 9, the negative pressure nozzle 307 is connected to the airway interface 308 at the bottom end of the lower bracket 10. At this time, an air pressure that adsorbs into the capsule hole 8 will be generated in the capsule hole 8 at the top end of the upper bracket 9, so as to push the large capsule shell into the capsule hole 8 at the top end of the upper bracket 9 more quickly. The pushing of the air pressure can make the large capsule shell pushed downward by the ejector rod fall into the capsule hole 8 at the top end of the upper bracket 9 more accurately.

[0086] Specifically, in this embodiment, at the same time, the large capsule shell that falls into the capsule hole 8 at the top end of the upper bracket 9 uses the air pressure at the bottom end of the lower bracket 10, and the stepped contour in the capsule hole 8 at the top end of the upper bracket 9 to automatically separate the capsule cap and the capsule body of the large capsule shell. The separated capsule cap stays in the capsule hole 8 at the top end of the upper bracket 9, and the separated capsule body stays in the capsule hole 8 of the lower bracket 10, realizing the automatic separation of the large capsule body and cap.

[0087] A fixed pulley three 311 is arranged on the surface of the sorting base 206, a second rope buckle 301 is arranged at the bottom of the sorting forklift 214, a second rope buckle 301 is fixed at the top end of the air suction base 304, a second rope 302 is connected to the second rope buckle 301 at the bottom of the sorting forklift 214, and the other end of the second rope 302 passes through the fixed pulley three 311 and is fixedly connected to the second rope buckle 301 at the top end of the air suction base 304.

[0088] Specifically, in this embodiment, the up-and-down linkage of the ejector rod 208 and the negative pressure suction nozzle 307 is realized by the reciprocating movement of the sorting forklift 214, which drives the reciprocating lifting of the ejector rod 208 and the negative pressure suction nozzle 307 by using the first rope 213 and the second rope 302. This transmission enables the ejector rod 208, the negative pressure suction nozzle 307 and the sorting forklift 214 to maintain sensitive response and high-speed reciprocating cooperation during the high-speed movement, thus effectively improving the production and processing speed of the automated production line.

[0089] Among them, the capsule combining mechanism 4 includes a cylinder support plate 401 fixed on the top of the fixed base 25. A double-acting piston cylinder 402 is fixedly installed on the surface of the cylinder support plate 401. A piston rod extends from each end of the double-acting piston cylinder 402. A capsule pushing rod 403 is arranged at the top end of each piston rod of the double-acting piston cylinder 402. The capsule pushing rod 403 located at the bottom end of the lower bracket 10 extends into the capsule hole 8 of the lower bracket 10 through the air passage interface 308, and the large capsule body in the capsule hole 8 of the lower bracket 10 is buckled with the large capsule cap in the capsule hole 8 of the upper bracket 9 to realize capsule combination.

[0090] Among them, the oil injection mechanism 3 includes a liquid storage hopper 311 arranged above the intermittent turntable 6. A highly accurate metering liquid pumping pump is arranged inside the liquid storage hopper 311. An infusion pipe 312 is arranged at the bottom of the liquid storage hopper 311. The bottom of the infusion pipe 312 is communicated with an oil injection needle base 313. A plurality of oil injection needles 314 corresponding to the capsule holes 8 on the surface of the lower bracket 10 are arranged at the bottom of the oil injection needle base 313. The plurality of oil injection needles 314 simultaneously inject liquid into the large capsule bodies in the corresponding capsule holes 8 on the surface of each lower bracket 10, and the metering of the injected liquid is accurately controlled by the highly accurate metering liquid pumping pump. Among them, this component is a prior art. In this embodiment, only a common oil injection mechanism is provided. Any oil injection mechanism in the prior art that can achieve the technical effects of this application can be used as a replacement for the oil injection mechanism 3 of this application.

[0091] The collecting mechanism 5 includes a feeding motor 16 fixed to the periphery of the intermittent turntable 6. The feeding motor 16 has an output shaft extending upward. At the top end of the output shaft of the feeding motor 16, a feeding swing rod 24 is installed. The feeding swing rod 24 is arranged on the upper surface of the lower bracket 10. The collecting mechanism 5 also has a top capsule rod 403 similar to the capsule combining mechanism 4. There is only one top capsule rod 403 and it is arranged at the bottom of the lower bracket 10. The collecting mechanism 5 also has a cylinder support plate 401 fixed to the top end of the fixed base 25. The surface of the cylinder support plate 401 is fixed with a pneumatic cylinder with one-way expansion and contraction. The pneumatic cylinder has a piston rod extending downward. The top capsule rod 403 is fixed to the top end of the piston rod extending downward from the pneumatic cylinder.

[0092] Among them, when the lower bracket 10 and the upper bracket 9 after buckling are moved to the position of the collecting mechanism 5, the top capsule rod 403 passes through the airway interface 308 and extends into the capsule hole 8 of the lower bracket 10, and the large capsule after capsule combining is jacked up from the capsule hole 8 of the lower bracket 10 to the top end of the upper bracket 9. At this time, the feeding motor 16 drives the feeding swing rod 24 to push the large capsule at the top end of the upper bracket 9 into the lower collecting chute and collecting box.

[0093] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. The descriptions in the above embodiments and the specification only illustrate the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of the present invention claimed is defined by the appended claims and their equivalents.

Claims

1. A method for producing and processing capsule-type genetically recombinant superoxide dismutase, characterized in that: The capsule-type gene recombinant superoxide dismutase production and processing method mainly includes the following steps: S1: Preparation of capsule materials: prepare the genetically recombinant superoxide dismutase particles to be encapsulated and prepare an appropriate amount of capsule shell materials. Two types of capsule shell materials are prepared, namely large capsules and small capsules; S2: Capsule particle encapsulation: The staff takes out the genetically recombinant superoxide dismutase particles and encapsulates the genetically recombinant superoxide dismutase particles into the small capsule shell to complete the production of the core components of the large capsule; S3: Large capsule separation: The large capsule cap of the large capsule shell is separated from the large capsule body by using an automated production line, and the separated large capsule shell is transported by staggered transmission; S4: filling capsule particles; during the dislocation transmission process of the large capsule separated in step S3, the capsule particles encapsulated in step S2 are placed in the large capsule separated in the dislocation as the inner core of the large capsule; S5: adding liquid and filling; the large capsule body with capsule particles in step S4 continues to be staggered and transported in the automated production line. During the staggered transport process, a small amount of liquid is injected into the large capsule body with capsule particles; S6: capsule closing station; the dislocated large capsule body and the large capsule cap are closed to completely seal the encapsulated capsule particles and liquid in the large capsule to form a large capsule with a capsule-in-capsule structure; S7: Capsule collection: collect the large capsules after closure and send them to the later stage for packaging.

2. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 1, characterized in that: The steps S4 to S7 described above are mainly completed by an automated production line, which includes an intermittent turntable that rotates intermittently in a cycle, and a capsule throwing mechanism, a particle throwing mechanism, an oiling mechanism, a capsule closing mechanism, and a collecting mechanism that are arranged at equal intervals around the outer circumference of the intermittent turntable, wherein the capsule throwing mechanism is used to throw large capsules, the middle part of the intermittent turntable is fixed to the top of the central shaft, the bottom end of the central shaft is rotatably connected to the top of the fixed base, the fixed base is fixed to the ground, a servo motor is fixedly installed on the top of the fixed base, the servo motor has an output shaft extending upward, a driving gear is installed on the top of the output shaft of the servo motor, a driven gear is fixedly installed on the outer circumference of the central shaft, and the driven gear is meshed with the driving gear; A second-order turntable is arranged at the bottom of the intermittent turntable, a connecting bracket is fixedly connected between the second-order turntable and the intermittent turntable, the second-order turntable rotates synchronously with the intermittent turntable through the connecting bracket, the outer circumferential surface of the intermittent turntable is provided with an upper bracket at equal intervals around the circumference, the surface of the upper bracket is provided with through capsule holes, the top of the second-order turntable is provided with a bracket support at equal intervals around the circumference, a lower bracket is installed on the surface of each bracket support, and the top surface of the lower bracket is also provided with capsule holes corresponding to the surface of the upper bracket.

3. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 2, characterized in that: A bottom support plate is provided at the bottom of the second-stage turntable, and the bottom support plate is a disc structure. The top surface of the bottom support plate is provided with an undulating walking slope. The top surface of the walking slope rises and falls from the bottom of the oil injection mechanism to the middle position between the capsule closing mechanism and the grain-feeding mechanism, and the top surface of the walking slope between the oil injection mechanism and the grain-feeding mechanism is kept horizontal and at the same height. A slope support tube is provided at the bottom of the bottom support plate, and the slope support tube is fixed to the top of the fixed base.

4. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 3, characterized in that: Each of the lower brackets includes a spring base arranged on the top surface of the second-step turntable, a lifting shaft rod passing through the surface of the second-step turntable and the inside of the spring base is arranged at the bottom of the bracket support, the lifting shaft rod extends toward the bottom of the second-step turntable, the lifting shaft rod is axially slidably connected with the second-step turntable and the spring base, a walking roller is arranged at the bottom of the lifting shaft rod extending toward the bottom of the second-step turntable, a support spring is connected between the bottom of the lifting shaft rod and the spring base, and the walking roller is rollingly connected to the top surface of the walking ramp.

5. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 2, characterized in that: A special-shaped wheel is arranged between the bottom of the intermittent turntable and the second-stage turntable, the top surface of the special-shaped wheel is clearance-fitted or slidingly connected with the bottom surface of the intermittent turntable, the surface of the bracket support is axially slidingly connected with a movable shaft rod, the lower bracket is fixed to the outermost end of the movable shaft rod, and a roller assembly is arranged at the other end of the movable shaft rod, and the roller assembly is rollingly connected to the surface of the special-shaped wheel, and a bracket spring is arranged at the top end of the movable shaft rod equipped with the roller assembly and the surface of the bracket support.

6. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 5, characterized in that: The roller assembly comprises a steel ball sleeve fixed on the top end of the movable shaft rod, a rolling steel ball is rollingly connected inside the steel ball sleeve, and the rolling steel ball is in rolling contact with the surface of the special-shaped wheel.

7. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 2, characterized in that: The pelletizing mechanism comprises a cylinder bracket fixed on the top of a fixed base, a pellet-pushing cylinder 1 is fixedly installed on the top of the cylinder bracket, a support arm is fixedly installed on the top of the cylinder bracket, a pellet hopper is fixedly installed on the top of the support arm, a support plate sleeve is provided at the bottom of the pellet hopper, a long block-shaped support plate is slidably connected to the middle of the support plate sleeve, a plurality of parallel capsule particle flow cavities are evenly spaced inside the support plate, the top of the capsule particle flow cavity passes through the pellet hopper, and a push rod is provided on the front end surface of the support plate; A sorting base is arranged at the front side of the cylinder bracket, and a plurality of forklift slideways are arranged at equal intervals on the surface of the sorting base. A sorting forklift is slidably connected in each forklift slideway on the surface of the sorting base, and the rear end of the sorting forklift is fixed to the top of the piston rod of the first particle pushing cylinder; A first pull rope buckle is provided at the top of the sorting forklift, and a first pull rope buckle is also provided on the surface of the support plate. The middle part of the support arm is rotatably connected to a fixed pulley 1, and the top of the support arm is rotatably connected to a fixed pulley 2. The first pull rope is connected to the first pull rope buckle on the surface of the support plate, and the other end of the first pull rope passes through the fixed pulley 2 and the fixed pulley 1 in sequence and is connected to the first pull rope buckle at the top of the sorting forklift.

8. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 7, characterized in that: The capsule throwing mechanism and the pellet throwing mechanism adopt the same structural setting in the method of delivering capsules, and the size of the capsule pellet flow cavity and the forklift slideway in the middle of the capsule throwing mechanism is slightly larger than the size of the capsule pellet flow cavity and the forklift slideway in the middle of the pellet throwing mechanism; The bag throwing mechanism also includes a guide slide bar arranged below the sorting base, the middle part of the guide slide bar is slidably connected with a suction base, the surface of the suction base is provided with a suction nozzle sleeve, the middle part of the suction nozzle sleeve is provided with a through circular hole, a suction nozzle rod body is axially slidably connected in the circular hole of the suction nozzle sleeve, a negative pressure suction nozzle is arranged on the top end of the suction nozzle rod body, a compression spring is installed on the outer wall of the suction nozzle rod body, and an air inlet interface is arranged at the bottom of the suction nozzle rod body. A fixed pulley three is provided on the surface of the sorting base, a second pull rope buckle is provided at the bottom of the sorting forklift, a second pull rope buckle is fixed to the top of the suction base, a second pull rope is connected to the second pull rope buckle at the bottom of the sorting forklift, and the other end of the second pull rope passes through the fixed pulley three and is fixedly connected to the second pull rope buckle at the top of the suction base.

9. The method for producing and processing capsule-type genetically recombinant superoxide dismutase according to claim 2, characterized in that: The bag closing mechanism includes a cylinder support plate fixed on the top of a fixed base, a bidirectional piston cylinder is fixedly installed on the surface of the cylinder support plate, piston rods extend from both ends of the bidirectional piston cylinder, and a bag pushing rod is arranged on the top of each piston rod of the bidirectional piston cylinder.

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