External erection aid for men as well as preparation method and application of external erection aid

Abstract

The invention relates to an external erection aid for men as well as a preparation method and application of the external erection aid. The external erection aid for men is prepared from the following raw materials in parts by weight: 20 to 25 parts of traditional Chinese medicine powder, 8 to 15 parts of penetration enhancer, 5 to 10 parts of glycerol, 20 to 30 parts of absolute ethyl alcohol and 50 to 60 parts of water, wherein the traditional Chinese medicine powder is prepared from the following raw materials in parts by weight: 5-8 parts of herba epimedii, 10-15 parts of rosemary, 5-8 parts of fructus psoraleae, 5-8 parts of philippine flemingia root, 15-20 parts of gallnut, 5-10 parts of fructus cnidii and 10-15 parts of maca, and the mass ratio of the fructus psoraleae to the philippine flemingia root to the rosemary is 1: 1: (1.5-2); the penetration enhancer is selected from at least two of isosorbide dimethyl ether, nerol and bis-diethoxy diethylene glycol cyclohexane 1, 4-dicarboxylate. The erection aid can take effect quickly, prolong sexual intercourse time, assist erection and maintain male private parts, and is safe, free of irritation and small in side effect.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine external preparations, and specifically relates to a male external erection-aiding agent, its preparation method and application. Background Art

[0002] With the accelerating pace of modern life and great work and life pressure, the problem of male erectile dysfunction has become increasingly prominent. Premature ejaculation has a serious impact on the physical and mental health, quality of life and family harmony of men. Normal sexual function depends on the cooperation of multiple systems and a good mental and psychological state. Sexual dysfunction will occur when there are abnormalities in the nervous system, cardiovascular system, endocrine system, reproductive system or mental and psychological aspects. The causes of premature ejaculation include psychological factors, such as fear of sexual intercourse failure, emotional anxiety, masturbation habits, lack of sexual knowledge, poor cooperation between husband and wife, etc.; there are also organic factors, such as spinal cord system diseases, diabetes, cardiovascular diseases, pelvic fractures, urogenital system diseases, etc.

[0003] Common drugs for treating premature ejaculation are western medicines such as 5-hydroxytryptamine reuptake inhibitors and tricyclic antidepressants, but they have certain side effects. Although there are many traditional Chinese medicines that can improve male sexual function in traditional Chinese medicine, most of them are oral and mainly tonify the kidney. They are inconvenient to use and also neglect the maintenance of the male private parts skin. And the existing male erection-aiding and ejaculation-delaying agents still fail to solve the problems of slow onset and short ejaculation delay of external preparations. Summary of the Invention

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and provide a male external erection-aiding agent, its preparation method and application that can not only take effect quickly, extend the sexual intercourse time, assist erection, but also maintain the male private parts and have small side effects.

[0005] To achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0006] In the first aspect, the present invention provides a male external erection-aiding agent, which includes the following raw materials in parts by weight: 20-25 parts of traditional Chinese medicine powder, 8-15 parts of penetration enhancer, 5-10 parts of glycerol, 20-30 parts of absolute ethanol, and 50-60 parts of water; wherein, the traditional Chinese medicine powder is made from the following raw materials in parts by weight: 5-8 parts of epimedium, 10-15 parts of rosemary, 5-8 parts of psoralea fruit, 5-8 parts of Flemingia philippinensis, 15-20 parts of Chinese gall, 5-10 parts of cnidium fruit, and 10-15 parts of maca, and the mass ratio of psoralea fruit, Flemingia philippinensis and rosemary is 1:1:(1.5-2); the penetration enhancer is at least two of isosorbide dimethyl ether, nerol and bis-(diethoxydiglycol) cyclohexane-1,4-dicarboxylate.

[0007] In the present invention, the herb contains a large amount of flavonoids and icariin, which can dilate blood vessels and promote blood circulation in the penis. When applied externally, it can make the penis cavernous body more fully congested, thereby facilitating penis erection, enhancing the hardness and duration of erection, and playing an erection-aiding effect.

[0008] Rosemary contains 1,8-cineole and verbenone. 1,8-cineole is lipophilic, which interferes with the synthesis of intracellular lipids and increases the permeability of ingredients, that is, rosemary also has the effect of promoting transdermal absorption. At the same time, rosemary also has the effect of promoting vasodilation and promoting blood circulation in the penis. Moreover, 1,8-cineole that enters the blood through transdermal absorption can relieve anxiety and also help to reduce the latency time of ejaculation.

[0009] Psoralea corylifolia can "cure kidney leakage, open the life gate, warm the dantian, and gather the spirit". Through its multiple pharmacological effects such as tonifying the kidney and strengthening yang, consolidating semen and reducing urine, and enhancing immunity, it can effectively support the effects of delaying ejaculation, aiding erection, and strengthening yang.

[0010] Qianjinba has the effect of "replenishing qi and blood, and assisting yang". "Lingnan Herbal Medicine Collection Record" records that it can "dispel wind and dampness, treat numbness and pain in the hands and feet, rheumatic pain in the waist, treat bruises and injuries, and relax muscles and activate blood circulation."

[0011] Gallnut contains a large amount of tannic acid and other ingredients. Tannic acid has an astringent effect. When applied externally, it can coagulate the local protein of the glans penis, forming a protective film, reducing the sensitivity of the glans penis and thus prolonging the time of sexual intercourse.

[0012] Cnidium monnieri "is used to treat swelling and pain in the vagina of women, impotence, dampness and itching of the penis in men, eliminates numbness, wards off wind and cold, breaks up hard masses, opens the chest, reduces qi, induces sweating, and promotes urination". It is warm in nature, pungent in taste, and belongs to the kidney meridian. It has the effect of warming the kidney and assisting yang. It improves sexual dysfunction by warming and tonifying kidney yang and enhancing kidney function. Moreover, its warm properties can improve local blood circulation and enhance erectile function.

[0013] In addition to being rich in nutrients such as protein, amino acids, minerals, natural fiber, etc., maca also contains active substances such as macaene and macaamide. Among them, maca polysaccharides are also the most abundant active substance in maca, which can enhance the body's physical strength and endurance, thereby achieving a delayed effect.

[0014] In summary, the present invention aims to solve the problems of slow effect of external application of male erection-enhancing agents and low utilization rate of effective ingredients. Epimedium, rosemary, psoralea corylifolia, Eleutherodactyla odorata, gallnut, cnidium monnieri and maca are added as effective ingredients to the male erection-enhancing agent, and the erection-enhancing agent has a good erection-enhancing effect.

[0015] Preferably, the penetration enhancer is isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate in a mass ratio of 1:(0.5-0.7):(1.5-2). The present invention selects isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate as penetration enhancers, wherein isosorbide dimethyl ether has a good balance between hydrophilicity and lipophilicity, can interact with lipids and water in the stratum corneum of the skin, and increase the permeability of the skin, and this characteristic enables it to effectively promote the transdermal absorption of traditional Chinese medicine components; nerol can regulate the lipid structure of the stratum corneum of the skin, increase the permeability of the skin, and can also accelerate the structural changes of the stratum corneum of the epidermis, increase lipid fluidity, and thus promote the skin's absorption of foreign substances; bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate is a lipophilic and hydrophilic amphiphilic substance, which acts on the intercellular lipid pathway through epidermal penetration, temporarily opens the stratum corneum, and improves the penetration effect of the traditional Chinese medicine components on the stratum corneum. Isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate have a synergistic effect and can significantly improve the transdermal absorption of the ingredients. The three synergistically promote the absorption of erection-promoting and delayed ejaculation Chinese medicine by the male reproductive organ, shorten the onset time, and have the effect of moisturizing the skin or moisturizing.

[0016] Preferably, the male external erection aid comprises the following raw materials in parts by weight: 22 parts of Chinese medicine powder, 10 parts of penetration enhancer, 8 parts of glycerin, 26 parts of anhydrous ethanol and 54 parts of water; wherein the Chinese medicine powder is made of the following raw materials in parts by weight: 6 parts of epimedium, 12 parts of rosemary, 6 parts of psoralea corylifolia, 6 parts of clematis odoratus, 18 parts of gallnut, 7 parts of cnidium monnieri and 12 parts of maca.

[0017] In a second aspect, the present invention provides a method for preparing the male external erection aid, comprising the following steps:

[0018] (1) crushing epimedium, rosemary, psoralea corylifolia, radix schonophyllae, gallnut, cnidium monnieri and maca to obtain crude Chinese medicine powder, adding 5-6 times the total mass of ethanol aqueous solution of the crude Chinese medicine powder to mix, placing at 70-75° C. in a nitrogen atmosphere for reflux extraction 2-3 times, each time for 1-2 hours, combining the extracts, cooling, and filtering to remove ethanol to obtain a Chinese medicine extract;

[0019] (2) After purifying the Chinese medicine extract, drying it, and crushing it to 200-300 meshes to obtain Chinese medicine powder;

[0020] (3) The Chinese medicine powder obtained in step (2) is stirred and mixed with a penetration enhancer, glycerol, anhydrous ethanol and water to obtain the male external erection aid.

[0021] Preferably, in step (1), the mass concentration of the ethanol aqueous solution is 70-80%.

[0022] Preferably, in step (2), the purification treatment is to use a macroporous adsorption resin to adsorb and purify the traditional Chinese medicine extract.

[0023] Preferably, in step (3), the stirring speed is 300-400 r / min and the stirring time is 10-20 min.

[0024] In a third aspect, the present invention provides the use of the male external erection aid described in the first aspect in the preparation of male products.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] (1) The erectile aid of the present invention is to solve the problem of slow effect of external application. It does not add western medicine ingredients, but selects ingredients that can be used externally or taken internally, namely, a combination of epimedium, rosemary, psoralea corylifolia, radix quinquefolii, gallnut, cnidium monnieri and maca, which can effectively prolong the time of sexual intercourse and help erection. Among them, rosemary can promote transdermal absorption and vasodilation, providing a better environment for other ingredients to absorb and play a role; psoralea corylifolia directly supports sexual function by tonifying the kidney and strengthening yang and consolidating semen and reducing urine; radix quinquefolii further enhances the overall effect by tonifying qi and blood, assisting yang and relaxing muscles and activating collaterals. All three are indispensable in the formula.

[0027] (2) The present invention uses dimethyl isosorbide, nerol, and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate as penetration enhancers, which can increase the permeability of the skin, synergistically promote the transdermal absorption of traditional Chinese medicine ingredients, shorten the onset time, and moisturize the skin. DETAILED DESCRIPTION

[0028] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0029] In the following examples and comparative example 1, the sources of the raw materials used are as follows:

[0030] Epimedium, rosemary, psoralea corylifolia, radix quinatae, gallnut, cnidium monnieri, and maca were purchased from Guangzhou Qingping Chinese herbal medicine market;

[0031] Isosorbide dimethyl ether: manufacturer is Shanghai Haohong Biopharmaceutical Technology Co., Ltd., model number is 1214907;

[0032] Nerolidol: Manufacturer: Tianjin Xiensi Biochemical Technology Co., Ltd., model number: D-74435;

[0033] Bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate: The manufacturer is Shandong Shoucheng Chemical Co., Ltd., and the model is Neosolue-Aqulio.

[0034] Unless otherwise specified, other materials, reagents, etc. used in the examples and comparative examples can be obtained from commercial sources.

[0035] Example 1

[0036] A male external erection aid comprises the following raw materials in parts by weight: 22 parts of Chinese medicine powder, 10 parts of a penetration enhancer, 8 parts of glycerol, 26 parts of anhydrous ethanol and 54 parts of water; wherein the Chinese medicine powder is made from the following raw materials in parts by weight: 6 parts of epimedium, 12 parts of rosemary, 6 parts of psoralea corylifolia, 6 parts of kelp, 18 parts of gallnut, 7 parts of cnidium monnieri and 12 parts of maca; the penetration enhancer is isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate in a mass ratio of 1:0.6:1.7.

[0037] The preparation method of the male external erection aid comprises the following steps:

[0038] (1) crushing epimedium, rosemary, psoralea corylifolia, radix schonophorae flavescentis, gallnut, cnidium monnieri and maca to obtain crude Chinese medicine powder, adding 75% ethanol aqueous solution with a mass concentration of 5 times the total mass of the crude Chinese medicine powder to mix, placing in a nitrogen atmosphere at 70° C. and reflux extraction for 3 times, each time for 1.5 hours, combining the extracts, cooling, and filtering to remove ethanol to obtain a Chinese medicine extract;

[0039] (2) purifying the Chinese medicine extract with a macroporous adsorption resin, drying it, and crushing it to 200 meshes to obtain Chinese medicine powder;

[0040] (3) The Chinese medicine powder obtained in step (2) is stirred and mixed with a penetration enhancer, glycerol, anhydrous ethanol and water at a speed of 350 r / min for 15 min to obtain the male external erection aid.

[0041] Example 2

[0042] A male external erection aid comprises the following raw materials in parts by weight: 20 parts of Chinese medicine powder, 8 parts of a penetration enhancer, 5 parts of glycerol, 20 parts of anhydrous ethanol and 50 parts of water; wherein the Chinese medicine powder is made from the following raw materials in parts by weight: 5 parts of epimedium, 10 parts of rosemary, 5 parts of psoralea corylifolia, 5 parts of kelp, 15 parts of gallnut, 5 parts of cnidium monnieri and 10 parts of maca; the penetration enhancer is isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate in a mass ratio of 1:0.5:1.5.

[0043] The preparation method of the male external erection aid comprises the following steps:

[0044] (1) crushing epimedium, rosemary, psoralea corylifolia, radix schonophyllae, gallnut, cnidium monnieri and maca to obtain crude Chinese medicine powder, adding 70% ethanol aqueous solution with a mass concentration of 5 times the total mass of the crude Chinese medicine powder to mix, placing in a nitrogen atmosphere at 70° C. and reflux extraction for 3 times, each time for 1 hour, combining the extracts, cooling, and filtering to remove ethanol to obtain a composite extract;

[0045] (2) purifying the extract of the composition with a macroporous adsorption resin, drying it, and crushing it to 200 meshes to obtain a Chinese medicine powder;

[0046] (3) The Chinese medicine powder obtained in step (2) is stirred and mixed with a penetration enhancer, glycerol, anhydrous ethanol and water at a speed of 300 r / min for 20 min to obtain the male external erection aid.

[0047] Example 3

[0048] A male external erection aid comprises the following raw materials in parts by weight: 25 parts of Chinese medicine powder, 15 parts of a penetration enhancer, 10 parts of glycerol, 30 parts of anhydrous ethanol and 60 parts of water; wherein the Chinese medicine powder is made from the following raw materials in parts by weight: 8 parts of epimedium, 15 parts of rosemary, 8 parts of psoralea corylifolia, 8 parts of kelp, 20 parts of gallnut, 10 parts of cnidium monnieri and 15 parts of maca; the penetration enhancer is isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate in a mass ratio of 1:0.7:2.

[0049] The preparation method of the male external erection aid comprises the following steps:

[0050] (1) crushing epimedium, rosemary, psoralea corylifolia, radix schonophyllae, gallnut, cnidium monnieri and maca to obtain crude Chinese medicine powder, adding 80% ethanol aqueous solution with a mass concentration of 6 times the total mass of the crude Chinese medicine powder to mix, placing under 75° C. and nitrogen atmosphere for reflux extraction twice, each time for 2 hours, combining the extracts, cooling, and filtering to remove ethanol to obtain a composite extract;

[0051] (2) purifying the extract of the composition with a macroporous adsorption resin, drying it, and crushing it to 300 meshes to obtain a Chinese medicine powder;

[0052] (3) The Chinese medicine powder obtained in step (2) is stirred and mixed with a penetration enhancer, glycerol, anhydrous ethanol and water at a speed of 400 r / min for 10 min to obtain the male external erection aid.

[0053] Example 4

[0054] Example 4 is different from Example 1 in that: the total mass of the penetration enhancer remains unchanged, isosorbide dimethyl ether is not added, and the missing amount is made up with nerol and bis - diethoxydiglycol cyclohexane - 1,4 - dicarboxylate with a mass ratio of 0.6:1.7.

[0055] Example 5

[0056] Example 5 is different from Example 1 in that: the total mass of the penetration enhancer remains unchanged, nerol is not added, and the missing amount is made up with isosorbide dimethyl ether and bis - diethoxydiglycol cyclohexane - 1,4 - dicarboxylate with a mass ratio of 1:1.7.

[0057] Example 6

[0058] Example 6 is different from Example 1 in that: the total mass of the penetration enhancer remains unchanged, bis - diethoxydiglycol cyclohexane - 1,4 - dicarboxylate is not added, and the missing amount is made up with isosorbide dimethyl ether and nerol with a mass ratio of 1:0.6.

[0059] Comparative Example 1

[0060] Comparative Example 1 is different from Example 1 in that: rosemary is not added, and the missing amount is made up with psoralea fruit and Flemingia philippinensis with a mass ratio of 1:1.

[0061] Comparative Example 2

[0062] Comparative Example 2 is different from Example 1 in that: psoralea fruit is not added, and the missing amount is made up with Flemingia philippinensis and rosemary with a mass ratio of 1:2.

[0063] Comparative Example 3

[0064] Comparative Example 3 is different from Example 1 in that: Flemingia philippinensis is not added, and the missing amount is made up with psoralea fruit and rosemary with a mass ratio of 1:2.

[0065] Performance Test

[0066] 1. Test on the number of penile erections and the time of first erection in mice

[0067] Administration: A total of 45 healthy male Wistar rats at 24 months old were randomly divided into 9 groups, with 5 rats in each group. The administration groups were respectively given 0.15 g of the erection - promoting agent of Examples 1 - 6 and Comparative Examples 1 - 3. The pubic hair was removed with an 8% sodium sulfide aqueous solution. Select a quiet room, place the rats on a glass plate, evenly spray and apply the drug - containing spray on the pubic area, observe for 30 min, and record the number of penile erections under video surveillance. The penile head congestion and the exposure of the penile tip were counted as 1 erection. The results are shown in Table 1.

[0068] Table 1 Number of penile erections and time of first erection in mice

[0069]

[0070] As can be seen from Table 1, combining the data of Examples 1-3 and Examples 4-6, it can be known that the penetration enhancers in Examples 1-3 are selected as a compound of three components: isosorbide dimethyl ether, nerol, and bis-(diethoxydiethylene glycol) cyclohexane-1,4-dicarboxylate. The number of penile erections and the time to first erection in mice are significantly improved compared with those in Examples 4-6. This may be because the combined use of isosorbide dimethyl ether, nerol, and bis-(diethoxydiethylene glycol) cyclohexane-1,4-dicarboxylate can significantly improve the transdermal absorption of the components, and the three work together to promote the absorption of the traditional Chinese medicine for erectile enhancement and delayed ejaculation by the male genitalia, shortening the onset time.

[0071] Combining the data of Example 1 and Comparative Examples 1-3, it can be known that when rosemary, psoralea fruit, and Flemingia philippinensis Merr. ex Rolfe appear in the formula at the same time, the number of penile erections and the time to first erection in mice are higher than those in Comparative Examples 1-4, indicating that the synergistic effect of the three makes the topical agent show stronger effects in erectile enhancement, delayed ejaculation, and yang strengthening.

[0072] 2. Skin irritation test

[0073] The irritations of the erectile agents in each group were evaluated according to the single complete skin irritation test in item 2.3.5 of the "Disinfection Technical Specification" (2002 edition), and the skin irritation degree of the erectile agents to ordinary New Zealand white rabbits was detected.

[0074] Test animals: 30 ordinary New Zealand white rabbits, weighing 2.0 - 3.0 kg, provided by the Guangdong Provincial Center for Medical Laboratory Animals. They were divided into 10 groups in total, namely a control group and 9 experimental groups, with 3 rabbits in each group.

[0075] Test substances for the experimental groups: the erectile agents of Examples 1-6 and Comparative Examples 1-3; the control group selected clear water as the test substance.

[0076] The test animals were raised in an environment with a temperature of 18 - 23 °C and a relative humidity of 45 - 65%. 24 hours before the test, the hair on both sides of the back spine of the test animals was removed to avoid skin damage. The hair removal area was 3 cm * 3 cm. 0.5 mL of the test substance was taken and applied on a two-layer gauze (2.5 cm * 2.5 cm), and then directly applied to the skin of the test site on one side. A closed test was used. After 4 hours, the dressing was removed, and the contact area was washed with warm water. The erythema and edema reactions of the skin were observed at 1, 24, and 48 hours after removing the test substance. According to the scoring standard of the skin irritation reaction, the scores were integrated, and the average value of the skin irritation reaction scores at different time points of each group was obtained and recorded in Table 2.

[0077] The mean value of the highest skin irritation response score in each group was selected as the skin irritation index to evaluate the irritation and recorded in Table 2. Among them, a skin irritation index of 0 to <0.5 represents no irritation, 0.5 to <2.0 represents mild irritation, 2.0 to <6.0 represents moderate irritation, and 6.0 to <8.0 represents strong irritation.

[0078] Table 2 Conclusions of Skin Irritation Responses in Each Group

[0079] Group Stimulation Conclusion Example 1 Non-irritating Example 2 Non-irritating Example 3 Non-irritating Example 4 Non-irritating Example 5 Non-irritating Example 6 Non-irritating Comparative Example 1 Non-irritating Comparative Example 2 Non-irritating Comparative Example 3 Non-irritating Control Group Non-irritating

[0080] As can be seen from Table 2, the erection aids in Examples 1-6 and Comparative Examples 1-3 are all mild and non-irritating to the skin.

[0081] In summary, by defining the traditional Chinese medicine composition and the penetration enhancer composition, the erection aid of the present invention can not only take effect quickly, prolong sexual intercourse time, and assist in erection after external use, but also protect the male private parts and is safe and non-irritating.

[0082] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit the protection scope of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A male external erection aid, characterized in that: The invention comprises the following raw materials in parts by weight: 20-25 parts of Chinese medicine powder, 8-15 parts of a penetration enhancer, 5-10 parts of glycerol, 20-30 parts of anhydrous ethanol and 50-60 parts of water; wherein the Chinese medicine powder is made of the following raw materials in parts by weight: 5-8 parts of epimedium, 10-15 parts of rosemary, 5-8 parts of psoralea corylifolia, 5-8 parts of kelp scutellariae, 15-20 parts of gallnut, 5-10 parts of cnidium monnieri and 10-15 parts of maca, and the mass ratio of psoralea corylifolia, kelp scutellariae and rosemary is 1:1:(1.5-2); the penetration enhancer is at least two of isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate.

2. The male external erection aid according to claim 1, characterized in that: The penetration enhancer is isosorbide dimethyl ether, nerol and bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate in a mass ratio of 1:(0.5-0.7):(1.5-2).

3. The male external erection aid according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 22 parts of Chinese medicine powder, 10 parts of a penetration enhancer, 8 parts of glycerol, 26 parts of anhydrous ethanol and 54 parts of water; wherein the Chinese medicine powder is made from the following raw materials in parts by weight: 6 parts of epimedium, 12 parts of rosemary, 6 parts of psoralea corylifolia, 6 parts of kelp, 18 parts of gallnut, 7 parts of cnidium monnieri and 12 parts of maca.

4. The method for preparing the male external erection aid according to any one of claims 1 to 3, characterized in that: The following steps are involved: (1) crushing epimedium, rosemary, psoralea corylifolia, radix schonophyllae, gallnut, cnidium monnieri and maca to obtain crude Chinese medicine powder, adding 5-6 times the total mass of ethanol aqueous solution of the crude Chinese medicine powder to mix, placing at 70-75° C. in a nitrogen atmosphere for reflux extraction 2-3 times, each time for 1-2 hours, combining the extracts, cooling, and filtering to remove ethanol to obtain a Chinese medicine extract; (2) After purifying the Chinese medicine extract, drying it, and crushing it to 200-300 meshes to obtain Chinese medicine powder; (3) The Chinese medicine powder obtained in step (2) is stirred and mixed with a penetration enhancer, glycerol, anhydrous ethanol and water to obtain the male external erection aid.

5. The method for preparing the male external erection aid as claimed in claim 4, characterized in that: In the step (1), the mass concentration of the ethanol aqueous solution is 70-80%.

6. The method for preparing the male external erection aid as claimed in claim 4, characterized in that: In the step (2), the purification treatment is to use a macroporous adsorption resin to adsorb and purify the traditional Chinese medicine extract.

7. The method for preparing the male external erection aid as claimed in claim 4, characterized in that: In the step (3), the stirring speed is 300-400 r / min and the stirring time is 10-20 min.

8. Use of the male external erection aid according to any one of claims 1 to 3 in the preparation of male products.

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