Application method of cyclopofol combined with high-frequency jet ventilation in painless gastrointestinal endoscope for obese patients

Abstract

The invention discloses an application method of cyclopofol combined with high-frequency jet ventilation in a painless gastrointestinal endoscope for obese patients, and provides an application scheme of cyclopofol combined with high-frequency jet ventilation. Before an operation, BMI, airway, cardiopulmonary functions and complications of a patient are comprehensively evaluated, fasting and water prohibiting are completed, and equipment drugs are prepared. During anesthesia induction, a patient lies on the back, and after oxygen uptake and nitrogen removal, cyclopofol is intravenously injected according to the speed of 0.5-1 mg / kg / min until consciousness and eyelash reflex disappear. The mask or the nasal catheter is selected to be tightly connected with the airway, and the ventilation frequency is set to be 60-120 times per minute and other parameters according to the physical signs of the patient and is adjusted as required. In gastrointestinal endoscopy, the device is inserted after stable ventilation, 0.05-0.1 mg / kg cyclopofol is added according to conditions to maintain anesthesia, and vital signs such as heart rate, blood pressure and the like are tightly staring at in the whole process. After operation, ventilation and anesthesia are stopped, oxygen inhalation is conducted in a resuscitation room, and after consciousness is recovered, vital signs are stable and swallowing cough reflex is normal, the patient is sent back to a ward. The method effectively reduces the examination risk of obese patients, improves the comfort, and has wide application prospects.

Description

Technical Field

[0001] The present invention belongs to the technical field related to painless gastroscopy and colonoscopy for obese patients, and particularly relates to an application method of cycloprofol combined with high-frequency jet ventilation in painless gastroscopy and colonoscopy for obese patients. Background Technique

[0002] With the improvement of people's living standards, the proportion of obese people has gradually increased. When obese patients undergo painless gastroscopy and colonoscopy, they face many challenges. Due to the change in the airway anatomical structure of obese patients, such as the accumulation of fat in the head and neck, overgrowth of oropharyngeal soft tissues, etc., the respiratory tract becomes narrow, and at the same time, the functional residual capacity of the lungs and the chest wall compliance decrease, making it extremely easy to have risks such as airway obstruction and hypoxemia during the examination.

[0003] In the existing painless gastroscopy and colonoscopy, common anesthetic drugs such as propofol, although having a fast onset and fast metabolism, have adverse reactions such as respiratory depression, hypotension, and injection pain. For obese patients, these adverse reactions may further increase their examination risks. The new anesthetic drug cycloprofol, as an analogue of propofol, has the advantages of fast onset, strong effect, fast metabolism, and rapid awakening, and has a lower incidence of respiratory depression, hypotension, and injection pain, providing a new option for painless gastroscopy and colonoscopy for obese patients.

[0004] In addition, in terms of ventilation support, traditional oxygen therapy methods such as nasal catheters, nasopharyngeal tubes, and simple face masks are extremely likely to cause a decrease in SpO2 during the examination of obese patients and cannot meet the ventilation needs of obese patients during painless gastroscopy and colonoscopy. Therefore, a new ventilation technology is needed to ensure oxygenation of obese patients during the examination. High-frequency jet ventilation, as a new type of respiratory support technology, can provide high-flow gas and has potential advantages in maintaining airway patency and oxygenation. Summary of the Invention

[0005] The purpose of the present invention is to provide an application method of cycloprofol combined with high-frequency jet ventilation in painless gastroscopy and colonoscopy for obese patients to solve the problems raised in the above background technique.

[0006] To achieve the above purpose, the present invention provides the following technical solutions:

[0007] An application method of cycloprofol combined with high-frequency jet ventilation in painless gastroscopy and colonoscopy for obese patients, comprising the following steps:

[0008] Preoperative preparation:

[0009] Patient assessment: Conduct a comprehensive preoperative assessment of obese patients, including body mass index, airway condition, cardiopulmonary function, and comorbidities;

[0010] NPO (Nil per os): Inform the patient to fast for 6 - 8 hours and refrain from drinking water for 2 - 4 hours before the operation;

[0011] Equipment preparation: Prepare the high - frequency jet ventilation equipment, check its performance to ensure it can provide stable high - flow gas. At the same time, prepare relevant equipment such as an anesthesia machine and a monitor, and debug them to the normal working state;

[0012] Drug preparation: Prepare cycloprofol and other emergency drugs that may be needed, such as atropine, ephedrine, and adrenaline;

[0013] Anesthetic induction:

[0014] Patient position: The patient lies in the supine position with the head slightly tilted backward to keep the airway unobstructed;

[0015] Oxygen inhalation and denitrogenation: Administer pure oxygen to the patient through a mask at an oxygen flow rate of 8 - 10 L / min for 3 - 5 minutes;

[0016] Cycloprofol injection: Slowly inject cycloprofol intravenously at a rate of 0.5 - 1 mg / kg / min. Adjust the dose according to the patient's response. The general induction dose is 0.3 - 0.5 mg / kg until the patient loses consciousness and the eyelash reflex disappears;

[0017] Implementation of high - frequency jet ventilation:

[0018] Ventilation connection: Immediately after the completion of anesthetic induction, connect the interface of the high - frequency jet ventilation to the patient's airway. A specially designed mask or a nasal catheter can be used for connection to ensure a tight connection without air leakage;

[0019] Ventilation parameter setting: Set the parameters of high - frequency jet ventilation. The frequency is 60 - 120 times per minute, the driving pressure is 0.1 - 0.3 MPa, and the inhalation time is 0.08 - 0.12 seconds. Adjust according to the patient's blood oxygen saturation and end - tidal carbon dioxide partial pressure indicators;

[0020] Gastroscopy and colonoscopy examination:

[0021] Insertion of gastroscopy and colonoscopy: After the high - frequency jet ventilation is stable, the endoscopist slowly inserts the gastroscopy and colonoscopy for examination. During the operation, closely observe the patient's vital signs, including heart rate, blood pressure, blood oxygen saturation, end - tidal carbon dioxide partial pressure, etc.;

[0022] Anesthetic maintenance: According to the examination time and the patient's response, timely add cycloprofol with an additional dose of 0.05 - 0.1 mg / kg to maintain the patient's anesthetic depth. At the same time, pay attention to observing the patient's breathing condition to ensure the effect of high - frequency jet ventilation;

[0023] Post - operative recovery:

[0024] Cessation of ventilation and anesthesia: After the gastroscopy and colonoscopy are completed, first stop the high-frequency jet ventilation, and then stop injecting cycloprofol;

[0025] Oxygen inhalation and observation: Transfer the patient to the recovery room, continue to give oxygen through a mask, with an oxygen flow rate of 4-6 L / min, and closely observe the patient's consciousness recovery and vital sign changes;

[0026] Recovery assessment: After the patient's consciousness has fully recovered, the vital signs are stable, the patient can answer questions correctly, and the swallowing and cough reflexes have returned to normal, the patient can be sent back to the ward.

[0027] Preferably, in the patient assessment, for extremely high-risk obese patients with a BMI greater than 40 kg / m 2 it is necessary to further evaluate the degree of airway difficulty, and if necessary, use auxiliary means such as a fiberoptic bronchoscope to evaluate the airway condition.

[0028] Preferably, the gas source of the high-frequency jet ventilation device is medical compressed air or oxygen, and the device has a pressure monitoring and alarm function, and can issue an alarm in time when the driving pressure exceeds the set range.

[0029] Preferably, during the anesthesia induction process, the bispectral index (BIS) of the patient is monitored simultaneously, and the BIS value is maintained between 40 and 60 to accurately control the depth of anesthesia.

[0030] Preferably, during the gastroscopy and colonoscopy, if the patient's heart rate is lower than 50 beats per minute, inject 0.5 mg of atropine intravenously; if the systolic blood pressure is lower than 30% of the baseline value, inject 6-10 mg of ephedrine intravenously.

[0031] Preferably, during the postoperative recovery process, the modified Aldrete score is used to evaluate the patient's recovery. When the score reaches 9 or above, the patient can be sent back to the ward.

[0032] Compared with the prior art, the present invention provides a method for the application of cycloprofol combined with high-frequency jet ventilation in painless gastroscopy and colonoscopy for obese patients, which has the following beneficial effects:

[0033] Improve anesthesia safety: Compared with traditional propofol, cycloprofol has a lower incidence of respiratory depression, hypotension, and injection pain in obese patients. Its unique pharmacological properties make the anesthesia induction more stable, reduce emergencies caused by anesthetic drugs, create a more stable starting condition for gastroscopy and colonoscopy, and reduce the anesthesia risk.

[0034] Optimize ventilation guarantee: The high-frequency jet ventilation technology provides suitable respiratory support for obese patients. Obese patients have complex airway anatomy and special lung function, and traditional ventilation is prone to hypoxia. High-frequency jet ventilation can maintain airway patency and oxygenation with high-flow gas, avoid a sharp drop in SpO2 during the examination, and ensure the stability of cardiopulmonary function.

[0035] Precision anesthesia management: This method administers drugs according to the individual differences of patients. For example, the injection speed and dose of propofol cyclis are precisely regulated, and additional doses are administered in a timely manner during the anesthesia maintenance stage. Combining with real-time monitoring of the patient's vital signs, the anesthesia depth is just right, ensuring that the patient has no awareness and no body movement interference during the examination, and is also conducive to rapid postoperative recovery.

[0036] Reducing the probability of complications: Comprehensively applying propofol cyclis and high-frequency jet ventilation to comprehensively reduce the complications of obese patients during painless gastroscopy and colonoscopy. From scientific preoperative assessment and preparation to fine intraoperative operation and reasonable postoperative recovery, the whole process is controlled to reduce the risks of regurgitation and aspiration, hypoxemia, etc., improve the overall quality of the examination, and promote the comfortable recovery of patients. Description of the Drawings

[0037] Figure 1 It is a flow diagram of the present invention. Detailed Embodiments

[0038] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0039] The present invention provides Figure 1 as shown in

[0040] A method for the application of propofol cyclis combined with high-frequency jet ventilation in painless gastroscopy and colonoscopy for obese patients, comprising the following steps:

[0041] Preoperative preparation:

[0042] Patient assessment: Conduct a comprehensive preoperative assessment of obese patients, including body mass index, airway condition, cardiopulmonary function, and comorbidities;

[0043] Fasting and water deprivation: Instruct the patient to fast for 6-8 hours and refrain from drinking water for 2-4 hours before the operation;

[0044] Equipment preparation: Prepare high-frequency jet ventilation equipment, check its performance to ensure normal operation, and ensure that it can provide stable high-flow gas. At the same time, prepare relevant equipment such as an anesthesia machine and a monitor, and debug them to a normal working state;

[0045] Drug preparation: Prepare propofol cyclis and other emergency drugs that may be required, such as atropine, ephedrine, and adrenaline;

[0046] Anesthetic induction:

[0047] Patient position: The patient lies in the supine position with the head slightly tilted backward to maintain a patent airway;

[0048] Oxygen inhalation and denitrogenation: The patient is given pure oxygen inhalation through a mask at an oxygen flow rate of 8 - 10 L / min for 3 - 5 minutes;

[0049] Propofol cyclodextrin injection: Propofol cyclodextrin is slowly injected intravenously at an injection rate of 0.5 - 1 mg / kg / min. The dose is adjusted according to the patient's response. The general induction dose is 0.3 - 0.5 mg / kg until the patient loses consciousness and the eyelash reflex disappears;

[0050] Implementation of high - frequency jet ventilation:

[0051] Ventilation connection: After the completion of anesthesia induction, immediately connect the interface of high - frequency jet ventilation to the patient's airway. A specially designed mask or a nasal catheter can be used for connection to ensure a tight connection without air leakage;

[0052] Ventilation parameter setting: Set the parameters of high - frequency jet ventilation. The frequency is 60 - 120 times per minute, the driving pressure is 0.1 - 0.3 MPa, and the inspiratory time is 0.08 - 0.12 seconds. Adjust according to the patient's blood oxygen saturation and end - tidal carbon dioxide partial pressure indicators;

[0053] Gastroscopy and colonoscopy examination:

[0054] Insertion of gastroscope and colonoscope: After the high - frequency jet ventilation is stable, the endoscopist slowly inserts the gastroscope and colonoscope for examination. During the operation, closely observe the patient's vital signs, including heart rate, blood pressure, blood oxygen saturation, end - tidal carbon dioxide partial pressure, etc.;

[0055] Anesthesia maintenance: According to the examination time and the patient's response, propofol cyclodextrin is added appropriately. The additional dose is 0.05 - 0.1 mg / kg to maintain the patient's anesthesia depth. At the same time, pay attention to observing the patient's breathing condition to ensure the effect of high - frequency jet ventilation;

[0056] Post - operative recovery:

[0057] Stop ventilation and anesthesia: After the gastroscopy and colonoscopy examination, first stop the high - frequency jet ventilation, and then stop injecting propofol cyclodextrin;

[0058] Oxygen inhalation and observation: Transfer the patient to the recovery room and continue to give oxygen inhalation through a mask at an oxygen flow rate of 4 - 6 L / min. Closely observe the patient's consciousness recovery and changes in vital signs;

[0059] Recovery assessment: After the patient's consciousness has fully recovered, the vital signs are stable, the patient can answer questions correctly, and the swallowing and cough reflexes have returned to normal, the patient can be transferred back to the ward.

[0060] Example 1

[0061] Preoperative preparation:

[0062] Patient assessment: The patient is a 35-year-old male with a BMI of 40 kg / m 2 , falling into the category of obesity. After assessment, the Mallampati classification is grade III, the thyromental distance is 6 cm, and the mouth opening is 3 cm, indicating certain difficulties in the airway. The electrocardiogram shows sinus tachycardia, the chest X-ray shows increased pulmonary markings, and the pulmonary function test shows mild obstructive ventilatory dysfunction. The patient has a history of hypertension, and the blood pressure is controlled at around 140 / 90 mmHg.

[0063] Fasting and water deprivation: Instruct the patient to fast after 10 pm the night before surgery and to refrain from drinking water for 4 hours before surgery to reduce the risk of gastric content reflux and aspiration.

[0064] Equipment preparation: Select a high-frequency jet ventilation device, carefully check the gas source and power supply connections to ensure that the flow rate and pressure adjustment functions are normal. At the same time, prepare the anesthesia machine and monitor, and debug to ensure that all monitoring functions are normal.

[0065] Drug preparation: Prepare propofol cyclodextrin injection, as well as emergency drugs such as atropine, ephedrine, and adrenaline.

[0066] Anesthetic induction:

[0067] Patient position: The patient lies supine on the examination bed, with the head slightly tilted back and the shoulders elevated to straighten the airway naturally for better ventilation.

[0068] Oxygen inhalation and denitrogenation: Administer pure oxygen through a mask at an oxygen flow rate of 10 L / min for 5 minutes to fully increase the oxygen reserve in the body.

[0069] Propofol cyclodextrin injection: After establishing an intravenous infusion route through a peripheral vein, slowly inject propofol cyclodextrin at an injection rate of 0.8 mg / kg / min, with an induction dose of 0.4 mg / kg. Closely observe the patient's reaction during the injection. Stop the injection when the patient loses consciousness and the eyelash reflex disappears.

[0070] Implementation of high-frequency jet ventilation:

[0071] Ventilation connection: Use a specially designed mask to closely fit the patient's face to ensure no air leakage, and firmly connect the mask to the connecting tube of the high-frequency jet ventilation device.

[0072] Ventilation parameter setting: Initially set the frequency at 80 times / minute, the driving pressure at 0.2 MPa, and the inhalation time at 0.1 second.

[0073] Gastroscopy and colonoscopy examination:

[0074] Insertion of gastroscope and colonoscope: After the endoscopic doctor stabilized the high-frequency jet ventilation for 1 minute, the gastroscope was slowly inserted for examination. During the examination, the vital signs of the patient were closely observed. The oxygen saturation was maintained at 95%-100%, the heart rate was 80-100 beats per minute, the blood pressure was about 130 / 80 mmHg, and the end-tidal carbon dioxide partial pressure was maintained at 35-45 mmHg.

[0075] Anesthesia maintenance: The examination lasted for 15 minutes. At 10 minutes after the start, the patient had slight body movement, and 0.08 mg / kg of cycloprofol was added. After that, the patient maintained a stable state.

[0076] Postoperative recovery:

[0077] Stop ventilation and anesthesia: After the gastroscope and colonoscope examination was completed, the high-frequency jet ventilation was immediately stopped, and at the same time, the injection of cycloprofol was stopped.

[0078] Oxygen inhalation and observation: The patient was transferred to the recovery room, and oxygen was administered through a mask at an oxygen flow rate of 5 L / min. It was observed that the patient's consciousness gradually recovered. After 5 minutes, the patient could answer questions correctly.

[0079] Recovery assessment: After 10 minutes, the patient's vital signs were stable, the swallowing and cough reflexes returned to normal, and the patient was sent back to the ward.

[0080] Example 2

[0081] Preoperative preparation:

[0082] Patient assessment: The patient was a 40-year-old female with a BMI of 38 kg / m 2 . The Mallampati classification was grade II, the thyromental distance was 7 cm, the mouth opening was 3.5 cm, and the airway condition was relatively good. The electrocardiogram was normal, the chest X-ray showed no obvious abnormalities, and the pulmonary function test was basically normal. The patient had diabetes mellitus, and the blood sugar was controlled at about 7 mmol / L on an empty stomach and about 10 mmol / L 2 hours after a meal.

[0083] Fasting and water deprivation: The patient fasted for 8 hours and was deprived of water for 2 hours before the operation.

[0084] Equipment preparation: Prepare a high-frequency jet ventilation device of another brand and conduct a comprehensive inspection and debugging. At the same time, prepare the supporting anesthesia and monitoring equipment.

[0085] Drug preparation: Prepare cycloprofol and related first-aid drugs.

[0086] Anesthetic induction:

[0087] Patient position: The patient took the supine position with the head and neck naturally extended.

[0088] Oxygen inhalation and denitrogenation: The patient was given oxygen inhalation and denitrogenation through a mask at an oxygen flow rate of 8 L / min for 3 minutes.

[0089] Propofol cyclododecanoate injection: Propofol cyclododecanoate was slowly injected intravenously at a rate of 0.6 mg / kg / min, and the induction dose was 0.35 mg / kg. The patient's consciousness disappeared rapidly.

[0090] Implementation of high-frequency jet ventilation:

[0091] Ventilation connection: A nasal catheter was used to connect to the high-frequency jet ventilation device, ensuring that the insertion depth of the nasal catheter was appropriate and firmly fixed.

[0092] Ventilation parameter setting: The frequency was set at 100 times per minute, the driving pressure was 0.15 MPa, and the inspiratory time was 0.09 seconds.

[0093] Gastrointestinal endoscopy examination:

[0094] Insertion of gastrointestinal endoscope: The endoscopist performed colonoscopy after the ventilation was stable. During the examination, the patient's vital signs were stable, the oxygen saturation remained above 96%, the heart rate was 70 - 90 beats per minute, the blood pressure was 120 - 130 / 70 - 80 mmHg, and the end-tidal carbon dioxide partial pressure was within the normal range.

[0095] Anesthesia maintenance: The examination lasted for 20 minutes, and propofol cyclododecanoate was supplemented twice according to the patient's response, 0.06 mg / kg each time.

[0096] Postoperative recovery:

[0097] Stopping ventilation and anesthesia: Ventilation and anesthesia drug injection were stopped after the examination.

[0098] Oxygen inhalation and observation: The patient was given oxygen inhalation in the recovery room at an oxygen flow rate of 4 L / min, and the patient's consciousness began to recover after 3 minutes.

[0099] Recovery assessment: After 8 minutes, the patient was fully recovered, with stable vital signs and no discomfort symptoms, and was sent back to the ward.

[0100] It can be clearly seen from the above embodiments that the application method of propofol cyclododecanoate combined with high-frequency jet ventilation in painless gastrointestinal endoscopy for obese patients can effectively improve the safety and comfort of painless gastrointestinal endoscopy for obese patients, reduce the occurrence of anesthesia-related complications, and has significant clinical application value. In actual application, the parameters and operation details of each step can be appropriately adjusted according to the specific situation of the patient to achieve the best examination effect.

[0101] Finally, it should be noted that the above are only preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A method for using propofol combined with high-frequency jet ventilation in painless gastroenteroscopy in obese patients, characterized in that: The following steps are involved: Preoperative preparation: Patient assessment: Obese patients should undergo a comprehensive preoperative assessment, including body mass index, airway status, cardiopulmonary function, and comorbidities; Fasting and water restriction: inform the patient to fast for 6-8 hours and water restriction for 2-4 hours before surgery; Equipment preparation: prepare high-frequency jet ventilation equipment, check whether its performance is normal, and ensure that it can provide stable high-flow gas. At the same time, prepare anesthesia machines, monitors and other related equipment, and debug them to normal working conditions; Medication preparation: Prepare cyproconazole and other emergency medications that may be needed, such as atropine, ephedrine, and epinephrine; Induction of anesthesia: Patient position: The patient lies in supine position with the head tilted back slightly to keep the airway open; Oxygen inhalation and nitrogen removal: Give the patient pure oxygen inhalation through a mask, with an oxygen flow rate of 8-10L / min for 3-5 minutes; Propofol injection: Propofol is injected slowly intravenously at a rate of 0.5-1 mg / kg / min. The dose is adjusted according to the patient's response. The general induction dose is 0.3-0.5 mg / kg until the patient loses consciousness and the eyelash reflex disappears. High-frequency jet ventilation implementation: Ventilation connection: After anesthesia induction is completed, immediately connect the high-frequency jet ventilation interface to the patient's airway. A specially designed mask or nasal cannula can be used to ensure a tight connection without air leakage. Ventilation parameter setting: Set the parameters of high-frequency jet ventilation, with a frequency of 60-120 times / minute, a driving pressure of 0.1-0.3MPa, and an inspiratory time of 0.08-0.12 seconds, and adjust according to the patient's blood oxygen saturation and end-tidal carbon dioxide partial pressure indicators; Gastrointestinal endoscopy: Insertion of gastroenteroscope: After high-frequency jet ventilation is stabilized, the endoscopist slowly inserts the gastroenteroscope for examination and operation. During the operation, the patient's vital signs, including heart rate, blood pressure, blood oxygen saturation, and end-tidal carbon dioxide partial pressure, are closely observed; Anesthesia maintenance: according to the examination time and the patient's response, add propofol in time, the additional dose is 0.05-0.1mg / kg to maintain the patient's anesthesia depth. At the same time, pay attention to the patient's breathing to ensure the effect of high-frequency jet ventilation; Postoperative resuscitation: Stop ventilation and anesthesia: After the end of the gastrointestinal endoscopy, first stop high-frequency jet ventilation, then stop the injection of propofol; Oxygen inhalation observation: transfer the patient to the resuscitation room and continue to give oxygen through a mask at an oxygen flow rate of 4-6L / min. Closely observe the patient's recovery of consciousness and changes in vital signs; Awakening assessment: Once the patient's consciousness has fully recovered, vital signs are stable, he can answer questions correctly, and his swallowing and coughing reflexes have returned to normal, the patient can be sent back to the ward.

2. The method for using propofol combined with high-frequency jet ventilation in painless gastroenteroscopy in obese patients according to claim 1, characterized in that: In patient assessment, for patients with a BMI greater than 40 kg / m 2 For ultra-high-risk obese patients, the degree of airway difficulty needs to be further assessed, and auxiliary means such as fiberoptic bronchoscope should be used to assess the airway condition when necessary.

3. The method for using propofol combined with high-frequency jet ventilation in painless gastroenteroscopy in obese patients according to claim 1, characterized in that: The gas source of the high-frequency jet ventilation equipment is medical compressed air or oxygen, and the equipment has pressure monitoring and alarm functions, which can promptly issue an alarm when the driving pressure exceeds the set range.

4. The method for using propofol combined with high-frequency jet ventilation in painless gastroenteroscopy in obese patients according to claim 1, characterized in that: During the anesthesia induction process, the patient's bispectral index is monitored simultaneously, and the BIS value is maintained between 40-60 to accurately control the depth of anesthesia.

5. The method for using propofol combined with high-frequency jet ventilation in painless gastroenteroscopy in obese patients according to claim 1, characterized in that: During the gastrointestinal endoscopy, if the patient's heart rate is lower than 50 beats / minute, 0.5 mg of atropine is injected intravenously; if the systolic blood pressure is lower than 30% of the baseline value, 6-10 mg of ephedrine is injected intravenously.

6. The method for using propofol combined with high-frequency jet ventilation in painless gastroenteroscopy in obese patients according to claim 1, characterized in that: During postoperative resuscitation, the modified Aldrete score was used to assess the patient's awakening. When the score reached 9 points or above, the patient could be sent back to the ward.

Images