The invention discloses a
mucous membrane healing evaluation method based on
energy spectrum CT
iodine quantification, and belongs to the field of medical
image processing and clinical diagnose.The
mucous membrane healing evaluation method comprises the following steps that an
energy spectrum CT intestinal stage scanning image of a patient suffering from Crohn's
disease is obtained, and a three-dimensional
volume area of a diseased intestinal segment is delineated on an
energy spectrum CT
iodine substance
decomposition graph; selecting a reference
blood vessel area, and measuring an
iodine concentration value; calculating a normalized iodine concentration value, wherein the normalized iodine concentration value is equal to a result obtained by dividing the iodine concentration value of the
lesion intestinal segment by the iodine concentration value of the reference
blood vessel region; and comparing the normalized iodine concentration value with a preset threshold value 0.44, if the normalized iodine concentration value is less than 0.44, determining that the
mucous membrane is healed, otherwise, determining that the active
inflammation is caused. According to the scheme, traditional invasive
enteroscopy is replaced with energy spectrum CT
image analysis, contraindications of
endoscope operation, patient pain and examination blind areas are avoided, the acceptability and examination feasibility of patients are remarkably improved, and the method is particularly suitable for patients who cannot tolerate an
endoscope or need frequent follow-up visit.