Tumor electric field treatment system and electrode plate anomaly detection method

Abstract

The invention provides a tumor electric field treatment system and an electrode plate anomaly detection method. The system comprises at least one pair of electrode plates, each electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups, and grounding ends of the temperature detection units in each column group are connected to a grounding pin through a control switch. The temperature detection units in each row group are connected in series to form a temperature detection end, and the method comprises the following steps: under the condition that the temperature detection end corresponding to a target row group is switched to be communicated to a corresponding temperature sampling point, controlling the control switches corresponding to the column groups where the temperature detection units in the target row group are located to be closed in sequence, analog temperature signals detected by the corresponding one or more combinations of all the temperature detection units in the target row group are sampled respectively based on the corresponding temperature sampling points; and determining the temperature of each electrode unit in the target row group based on the respectively sampled analog temperature signals so as to judge whether the electrode slice is abnormal or not.

Description

Technical Field

[0001] The present application relates to tumor electric field therapy technology, and in particular to a method for detecting electrode sheet abnormalities and a tumor electric field therapy system. Background Art

[0002] Tumor electric field therapy is a treatment method that uses low-intensity, medium-high frequency alternating electric fields to prevent the formation of spindle microtubules during the mitosis of certain tumor cells, inhibit the separation of intracellular organelles during the cell division phase, and induce apoptosis of cells in the mitosis phase, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatment methods, tumor electric field therapy has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them vulnerable to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of tubulin by applying a directional force on intracellular polar particles (such as macromolecules and organelles). These processes may lead to physical damage to the cell membrane and apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow causes uneven distribution of the electric field around it. At the same time, under the influence of tumor electric field therapy, the electric field intensity at the cleavage furrow is significantly enhanced, and charged substances in the cell move towards the cleavage furrow, interfering with or even destroying the formation of the cell structure, ultimately leading to cell division failure and apoptosis.

[0004] In the tumor electric field therapy system in the related art, an electric field application device is used to transmit an alternating electric signal for tumor electric field therapy to an electrode sheet, and then an alternating electric field is applied to the tumor site of the patient through the electrode sheet for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the application site and the temperature will also increase accordingly. Therefore, it is necessary to monitor the temperature at the application site. When the temperature is too high, it is necessary to adjust the electric field intensity in time to reduce the risk of scalding the patient's skin due to excessive temperature.

[0005] The tumor electric field therapy system includes at least a pair of electrode sheets, and there are multiple electrode units in each electrode sheet. Even if the same alternating electric signal is applied to each electrode unit, the heat generated on each electrode unit will vary due to its different positions, that is, the temperature of each electrode unit on the entire electrode sheet will not be exactly the same. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature while the temperature of other electrode units is normal. To improve the effect of tumor electric field therapy, it is necessary to implement individual control of the over-temperature electrode units. However, for the electrode sheets in the related art, implementing individual control of the electrode units requires setting a conductive trace for each electrode unit in the substrate of the electrode sheet, which will increase the number of conductive traces in the electrode sheet substrate, making the electrode sheet difficult to bend, and the cable electrically connected to the electrode sheet will also thicken, increasing the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet and brings inconvenience to the patient. Summary of the Invention

[0006] This application aims to solve at least one of the technical problems in the related art to some extent. For this purpose, the first object of this application is to propose an electrode sheet abnormality detection method, which realizes comprehensive and precise control of the temperatures of each electrode unit of the corresponding electrode sheet through the multiplexing of dual-purpose signal lines and the linkage control between the multiplexing switching unit and the rectifying switching unit during the operation of the tumor electric field treatment system, so as to be able to monitor in a timely manner whether the electrode sheet is abnormal and improve the safety of the tumor electric field treatment system.

[0007] The second object of this application is to propose a computer-readable storage medium.

[0008] The third object of this application is to propose a tumor electric field treatment system.

[0009] To achieve the above object, the first aspect embodiment of this application provides an electrode sheet temperature detection method, which is applied to a tumor electric field treatment system. The tumor electric field treatment system includes at least a pair of electrode sheets. Each electrode sheet includes a plurality of electrode units and a plurality of temperature detection units. Each electrode unit can apply an alternating electric signal. Each temperature detection unit is correspondingly arranged for one electrode unit to detect the temperature at the corresponding electrode unit. Among them, the plurality of electrode units are configured to be at least two row groups and at least two column groups in circuit connection. Each temperature detection unit in each row group is connected in series to form a temperature detection terminal. The grounding terminals of each temperature detection unit in each column group are commonly connected to a grounding pin through a control switch. The method includes: when switching the temperature detection terminal corresponding to the target row group to be connected to the corresponding temperature sampling point, controlling the control switches corresponding to the column groups where each temperature detection unit in the target row group is located to be closed in sequence, so that the analog temperature signals detected by one or more corresponding combinations of all temperature detection units in the target row group are respectively sampled based on the corresponding temperature sampling point; determining the temperatures at each electrode unit in the target row group based on the respectively sampled analog temperature signals; and judging whether the electrode sheet is abnormal according to the temperature at each electrode unit.

[0010] The electrode sheet abnormality detection method according to an embodiment of the present application is applied to a tumor electric field therapy system. For each electrode sheet, a plurality of electrode units are divided into at least two row groups and at least two column groups in terms of circuit connection. The ground terminals of the temperature detection units corresponding to the electrode units in each column group are commonly connected to a ground pin through a control switch. The temperature detection units corresponding to the electrode units in each row group are connected in series. And based on the dual-purpose signal line, it is possible to achieve a complete switching and isolation between applying an alternating current signal to each electrode unit in each row group and temperature sampling at each temperature sampling point for the corresponding electrode unit, avoiding interference and ensuring the accuracy of the temperature sampling signal. Not only no new alternating current signal lines (i.e., AC lines) are added, but also the original alternating current signal lines are eliminated. Thus, fewer conductive traces can be used to control multiple electrode units in zones, which can not only improve the effect of tumor electric field therapy, but also be beneficial to the application of the electrode sheet. At the same time, it can achieve a comprehensive and accurate control of the temperature of each electrode unit of the corresponding electrode sheet, so as to be able to monitor in time whether the electrode sheet has an abnormality and improve the safety of the tumor electric field therapy system.

[0011] Optionally, determining whether the electrode sheet is abnormal according to the temperature at each electrode unit includes: when it is determined according to the temperature at each electrode unit that any one electrode unit in the corresponding electrode sheet has an abnormality or a fault, determining that the electrode sheet is unqualified.

[0012] Optionally, determining whether the electrode sheet is abnormal according to the temperature at each electrode unit includes: when it is determined according to the temperature at each electrode unit that there are electrode units with abnormalities or faults in the corresponding electrode sheet, determining the number of electrode units with abnormalities or faults; when the number of electrode units with abnormalities or faults reaches a preset threshold, determining that the electrode sheet needs to be replaced.

[0013] Optionally, when the number of electrode units with abnormalities or faults reaches a preset threshold, the method further includes: stopping applying an alternating current signal to each electrode unit of the electrode sheet.

[0014] Optionally, determining whether the electrode sheet is abnormal according to the temperature at each electrode unit includes: comparing the temperature at each electrode unit in the corresponding electrode sheet with a preset temperature threshold; and determining whether the temperature of the electrode sheet is abnormal according to the comparison result.

[0015] Optionally, determining whether the temperature of the electrode sheet is abnormal according to the comparison result includes: when the temperature at any one electrode unit in the corresponding electrode sheet exceeds the preset temperature threshold, determining that the temperature of the electrode sheet is abnormal.

[0016] Optionally, when the temperature at any one of the electrode units in the corresponding electrode sheet exceeds a preset temperature threshold, the method further includes: determining the number of over-temperature regions; and when the number of over-temperature regions exceeds a preset number threshold, stopping applying an alternating current signal to each electrode unit of the electrode sheet.

[0017] Optionally, when the control switch corresponding to the column group where the first temperature detection unit connected to the temperature detection end in the target row group is closed, the analog temperature signal detected by the first temperature detection unit is sampled based on the corresponding temperature sampling points.

[0018] Optionally, when the control switch corresponding to the column group where the second temperature detection unit adjacent to the first temperature detection unit in the target row group is closed, the analog temperature signal detected by the combination of the first temperature detection unit and the second temperature detection unit is sampled based on the corresponding temperature sampling points; when the control switch corresponding to the column group where the third temperature detection unit adjacent to the second temperature detection unit in the target row group is closed, the analog temperature signal detected by the combination of the first temperature detection unit, the second temperature detection unit, and the third temperature detection unit is sampled based on the corresponding temperature sampling points; and so on. When the control switch corresponding to the column group where the last temperature detection unit in the target row group is closed, the analog temperature signal detected by the combination of each temperature detection unit in the target row group is sampled based on the corresponding temperature sampling points.

[0019] Optionally, determining the temperature at each electrode unit in the target row group based on the respectively sampled analog temperature signals includes: determining the temperature at the first electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit; determining the temperature at the second electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit and the analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit; determining the temperature at the third electrode unit in the target row group based on the sampled analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit and the analog temperature signal corresponding to the combination of the first temperature detection unit, the second temperature detection unit, and the third temperature detection unit; and so on, determining the temperature at the fourth electrode unit to the last electrode unit in the target row group.

[0020] Optionally, the temperature detection end corresponding to each of the row groups is connected to the first switching end of the corresponding rectifier switching unit, the second switching end of the rectifier switching unit corresponding to each of the row groups is respectively connected to each electrode unit in the corresponding row group, the fixed end of the rectifier switching unit corresponding to each of the row groups is connected to the fixed end of the corresponding bidirectional switch through a dual-purpose signal line, the first end of the bidirectional switch corresponding to each of the rectifier switching units is the temperature sampling point of the corresponding row group, and the second end of the bidirectional switch corresponding to each of the rectifier switching units is simultaneously connected to the alternating power line, wherein, switching the temperature detection end corresponding to the target row group to be connected to the corresponding temperature sampling point includes: controlling the rectifier switching unit corresponding to the target row group to be linked with the corresponding bidirectional switch so that the temperature detection end corresponding to the target row group is connected to the corresponding temperature sampling point.

[0021] Optionally, when the first end of the bidirectional switch corresponding to the target row group is connected to the fixed end, the fixed end of the rectifier switching unit linked to the bidirectional switch is connected to the first switching end.

[0022] To achieve the above-mentioned purpose, the second aspect of the present application provides a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, the aforementioned electrode sheet abnormality detection method is implemented.

[0023] To achieve the above-mentioned purpose, the third aspect of the present application provides a tumor electric field therapy system, including a memory and a controller, wherein the memory stores a computer program, and when the computer program is executed by the controller, the aforementioned electrode sheet abnormality detection method is implemented.

[0024] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 A schematic diagram of a tumor electric field treatment system according to an embodiment of the present application;

[0026] Figure 2 for Figure 1 The schematic diagram of the partition structure of the electrode sheet of the tumor electric field treatment system shown;

[0027] Figure 3 for Figure 1 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown;

[0028] Figure 4 for Figure 1Schematic structural diagram of the electrode unit of the tumor electrotherapy system shown;

[0029] Figure 5 is Figure 1 Schematic circuit connection diagram of an electrode plate, an adapter and an electric field generator of the tumor electrotherapy system shown;

[0030] Figure 6 is Figure 1 Schematic block diagram of the internal structure of the adapter of the tumor electrotherapy system shown;

[0031] Figure 7 is Figure 1 Schematic block diagram of the internal structure of the electric field generator of the tumor electrotherapy system shown;

[0032] Figure 8 Schematic flow diagram of the electrode plate temperature detection method according to an embodiment of the present application;

[0033] Figure 9 Schematic flow diagram of the electrode plate abnormality detection method according to an embodiment of the present application;

[0034] Figure 10 Schematic flow diagram of the control method of the tumor electrotherapy system according to an embodiment of the present application;

[0035] Figure 11 Schematic flow diagram of the electrode plate type identification method according to an embodiment of the present application;

[0036] Figure 12 Schematic flow diagram of the signal control method for tumor electrotherapy according to an embodiment of the present application;

[0037] Figure 13 Schematic flow diagram of the electrode plate temperature detection method according to another embodiment of the present application;

[0038] Figure 14 Schematic flow diagram of the method for applying an alternating electric signal for tumor electrotherapy according to another embodiment of the present application;

[0039] Figure 15 Schematic flow diagram of the method for applying an alternating electric signal based on a temperature detection signal according to an embodiment of the present application;

[0040] Figure 16 Schematic flow diagram of the method for applying an alternating electric signal based on a temperature detection signal according to another embodiment of the present application;

[0041] Figure 17 Schematic diagram of the tumor electrotherapy system according to another embodiment of the present application;

[0042] Figure 18Schematic diagram of a tumor electric field therapy system according to another embodiment of the present application;

[0043] Figure 19 is Figure 18 Schematic diagram of the circuit connection between an electrode plate of the tumor electric field therapy system shown and an adapter;

[0044] Figure 20 Schematic diagram of a tumor electric field therapy system according to another embodiment of the present application;

[0045] Figure 21 Schematic diagram of a tumor electric field therapy system according to another embodiment of the present application;

[0046] Figure 22 Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to another embodiment of the present application and an adapter;

[0047] Figure 23 Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to another embodiment of the present application and an adapter;

[0048] Figure 23A Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to yet another embodiment of the present application and an adapter;

[0049] Figure 23B Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to yet another embodiment of the present application and an adapter;

[0050] Figure 23C Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to yet another embodiment of the present application and an adapter;

[0051] Figure 24 Schematic diagram of a tumor electric field therapy system according to another embodiment of the present application;

[0052] Figure 25 is Figure 24 Schematic diagram of the circuit connection between an electrode plate of the tumor electric field therapy system shown and an adapter;

[0053] Figure 26 Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to another embodiment of the present application and an adapter;

[0054] Figure 27 Schematic diagram of a tumor electric field therapy system according to another embodiment of the present application;

[0055] Figure 28 Schematic diagram of the circuit connection between an electrode plate of a tumor electric field therapy system according to another embodiment of the present application, an adapter, and an electric field generator;

[0056] Figure 29 isFigure 27 Schematic structural diagram of the electrode unit of the tumor electrotherapy system shown

[0057] Figure 30 is Figure 28 Schematic block diagram of the internal structure of the adapter of the tumor electrotherapy system shown

[0058] Figure 31 is Figure 28 Schematic block diagram of the internal structure of the electric field generator of the tumor electrotherapy system shown

[0059] Figure 32 Schematic flow diagram of the control method of the tumor electrotherapy system according to another embodiment of the present application

[0060] Figure 33 Schematic flow diagram of the signal control method for tumor electrotherapy according to another embodiment of the present application

[0061] Figure 34 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0062] Figure 35 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0063] Figure 36 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0064] Figure 37 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0065] Figure 38 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0066] Figure 39 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0067] Figure 40 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application

[0068] Figure 41 Schematic circuit connection diagram of an electrode sheet and an adapter of the tumor electrotherapy system according to another embodiment of the present application Detailed implementation manners

[0069] The embodiments of the technical solution of the present application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to illustrate the technical solution of the present application more clearly, so they are only examples and cannot be used to limit the protection scope of the present application.

[0070] Embodiment 1:

[0071] Figure 1 Shown is a schematic diagram of a tumor electrotherapy system 100 according to an embodiment of the present application. As Figure 1 shown, the tumor electrotherapy system 100 includes: at least a pair of electrode patches 13, an adapter 20 connected to the at least a pair of electrode patches 13, and an electric field generator 30 connected to the adapter 20. The at least a pair of electrode patches 13 can be arranged in pairs on the patient's body surface, such as Figure 1 the 4 electrode patches 13 in

[0072] As Figure 1 shown, in this embodiment, the number of electrode patches 13 is 4, and each electrode patch 13 includes a plurality of electrode units 33 with the same number. Each electrode unit 33 is electrically connected to the adapter 20, and the number of electrode units 33 on each electrode patch 13 is 20. In other embodiments, the tumor electrotherapy system 100 may also have more or fewer electrode patches 13; in other embodiments, each pair of electrode patches 13 has the same number of electrode units 33, and different pairs of electrode patches 13 may have different numbers of electrode units 33; in other embodiments, the number of electrode units 33 on each electrode patch 13 may be 9, 13, etc., which can be configured according to actual situations.

[0073] In this embodiment, the connection line between two electrode units 33 can be called a connection band, and the interval between the electrode units 33 can be adjusted through the connection band. If an electrode unit 33 is only connected to another electrode unit 33 through one connection band, then this electrode unit 33 is an electrode unit 33 at the free end. For example Figure 1Each of the shown electrode patches 13 has nine electrode units 33 at the free ends. The surrounding space where the electrode units 33 at the free ends are located is an open space, that is, the electrode units 33 at the free ends have a certain degree of freedom and can move freely within the open space. For example, the connecting band can be stretched or bent to a certain extent, enabling the electrode units 33 to move in various directions. In this embodiment, some of the electrode units 33 of each electrode patch 13 are set in the form of free ends because after the electrode patch is applied to the human body, due to the skin folds of the human body and the corresponding impedance changes, the electric fields of the electrode units 33 are inconsistent, resulting in inconsistent temperatures of the electrode units 33, and the electrode units 33 located on the periphery of the electrode patch 13 heat up faster. Therefore, when some of the electrode units 33 in the electrode patch 13 are at the free ends, the heat dissipation space of the electrode units 33 on the periphery can be increased by adjusting the electrode units 33 at the free ends, accelerating heat dissipation, and avoiding hypothermic burns of the human body caused by excessive local temperature. In addition, the application positions of the electrode units 33 at the free ends on the human body can be adjusted to flexibly apply the electrode units 33 at the free ends to the human body according to actual needs, improving the comfort of the human body and also improving the treatment effect.

[0074] Figure 3 is Figure 1 a schematic circuit connection diagram of the electrode patch 13 of the tumor electric field therapy system 100 shown and the adapter 20, Figure 4 which shows a schematic structural diagram of the electrode unit 33. It should be noted that: Figure 3 The arrangement of the shown electrode units 33 is for more clearly showing the electrical connection situation between an electrode patch 13 and the adapter 20, Figure 3 and the arrangement of the shown electrode units 33 does not represent the arrangement of the electrode units 33 in the spatial structure. Figure 3 which shows the cooperation between the rectifying and switching unit 16 and the multiplexing and switching unit (including a plurality of bidirectional switching switches 55) to realize the switching between temperature sampling and applying an alternating electric signal. As Figure 3As shown, multiple electrode units 33 in an electrode sheet 13 are configured into multiple row groups and multiple column groups. A rectifying and switching unit 16 with a first switching end 1, a second switching end 2, and a fixed end 3 is provided for each row group. The first switching end 1 of the rectifying and switching unit 16 is connected to each temperature detection unit 35 connected in series in the corresponding row group. The second switching end 2 of the rectifying and switching unit 16 is respectively connected to each electrode unit 33 in the corresponding row group. The fixed end 3 of the rectifying and switching unit 16 is connected to the multiplexing and switching unit through a one-way and two-way signal line 19. For example, when the 1 end of the bidirectional switching switch 55-1 is turned on and the 2 end is turned off, and the first switching end 1 and the fixed end 3 of the corresponding rectifying and switching unit 16 are connected, the temperature detection signal of the temperature detection unit 35 of the electrode unit 33 in the corresponding electrode sheet 13 can be obtained; or, when the 2 end of the bidirectional switching switch 55-1 is turned on and the 1 end is turned off, and the second switching end 2 and the fixed end 3 of the corresponding rectifying and switching unit 16 are connected, alternating current signals can be applied to each electrode unit 33 in the corresponding row group simultaneously.

[0075] Combined with Figure 1 、 Figure 3 and Figure 4 , the electrode sheet 13 includes: a substrate 31, multiple electrode units 33 electrically connected to the substrate 31 at intervals, multiple temperature detection units, 35 multiple rectifying and switching units 16, and a first cable 15 electrically connected to the substrate 31. The substrate 31 can be a flexible printed circuit board. Multiple conductive traces are embedded in the substrate 31, and the multiple conductive traces include multiple ground wires 18, multiple one-way and two-way signal lines 19, and a rectifying ground wire (not labeled) that grounds all the multiple rectifying and switching units 16. The first cable 15 has multiple core wires (not shown), and each core wire is respectively and electrically connected to the multiple ground wires 18, the multiple one-way and two-way signal lines 19, and the rectifying ground wire (not labeled) of the substrate 31 in one-to-one correspondence. In this embodiment, the total number of the ground wires 18, the one-way and two-way signal lines 19, and the rectifying ground wire (not labeled) embedded in the substrate 31 does not exceed 10, so the number of wires of the first cable 15 does not exceed 10.

[0076] The plurality of electrode units 33 are configured into a plurality of row groups and a plurality of column groups. In the present embodiment, 20 electrode units 33 are provided on each electrode sheet 13, and the 20 electrode units 33 are arranged in the order of 1 to 20 in the circuit connection, and are divided into four row groups and five column groups, that is, the 20 electrode units 33 are arranged in four rows and five columns in the circuit connection. Each electrode unit 33 corresponds to a temperature detection unit 35, and each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. The electrode unit 33 and the temperature detection unit 35 are both soldered to the substrate 31. Since the plurality of temperature detection units 35 are arranged one-to-one with the plurality of electrode units 33, the plurality of temperature detection units 35 are also arranged in four row groups and five column groups in the circuit connection. It should be noted that the arrangement method here is to more clearly show the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode unit 33 in the spatial structure, and its spatial structure may be as follows Figure 2 The structure shown as an array may also be other structures, such as petal-shaped or scattered, and may be regular or irregular. The electrode unit 33 is configured to apply an alternating electric field to the patient's tumor site. The temperature detection unit 35 is configured to detect the temperature of the patient's body surface attached to the electrode sheet 13, that is, the temperature at the corresponding electrode unit 33, and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed dual-purpose signal line 19 of the substrate 31 is respectively arranged in a one-to-one correspondence with the multiple row groups of the electrode unit 33, and is configured to transmit the alternating electric signal generated by the electric field generator 30 to each electrode unit 33 in the corresponding row group. That is, the electrode units 33 in the same row group can be connected to the same dual-purpose signal line 19 of the substrate 31 through the corresponding rectifier switching unit 16, and the electrode units 33 in different row groups are respectively connected in parallel through different dual-purpose signal lines 19 of the substrate 31. The dual-purpose signal line 19 of the substrate 31 is electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electric signal generated by the electric field generator 30 through the first cable 15 and the adapter 20 .

[0077] The multiple ground wires 18 are respectively arranged in one-to-one correspondence with multiple column groups of the electrode unit 33, and the multiple ground wires 18 are respectively used to sequentially short-circuit and ground the corresponding each temperature detection unit 35 in each column group. That is, the grounding terminals 35-1 of the multiple temperature detection units 35 in the same column group are all short-circuited through the same ground wire 18 of the substrate 31, and the grounding terminals 35-1 of the temperature detection units 35 in different column groups are respectively connected in parallel through different ground wires 18 of the substrate 31. During the time period of temperature detection, only one of the multiple ground wires 18 is conducting at the same moment, and the rest are disconnected. Each temperature detection unit 35 includes a temperature sensor 34, and both ends of each temperature sensor 34 are a signal terminal 34-2 and a grounding terminal 34-1 respectively. The multiple temperature sensors 34 in the same row group are connected in series, and one signal terminal 34-2 at the end of each row group is connected to a two-way signal line 19 through the corresponding rectifying and switching unit 16, and then connected to the DC power supply VCC through the corresponding bidirectional switch 55 and the corresponding voltage dividing resistor 53. After the grounding terminals 34-1 of the corresponding temperature sensors 34 in each column group are connected together through the corresponding diodes, they are then connected to the control switch 54 through the corresponding ground wire in the multiple ground wires 18 and then connected to the grounding pin GND. The tumor electric field treatment system 100 samples the analog temperature signals detected by one or more corresponding combinations of the corresponding all temperature sensors 34 of the electrode plate 13 by configuring the switching timings of the bidirectional switch 55 and the control switch 54.

[0078] Such as Figure 3As shown, all the temperature sensors 34 in the same row group are connected in series into a circuit line, and are connected to a two-purpose signal line 19 (such as one of the two-purpose signal lines 19-1, 19-2, 19-3, 19-4) through the corresponding rectifying and switching unit 16, and then are connected to the DC power supply VCC through the corresponding bidirectional switching switch 55. The grounding ends 34-1 of all the temperature sensors 34 in the same row group are respectively connected to the grounding pin GND by 5 ground wires 18 (such as ground wires 18-1, 18-2, 18-3, 18-4, 18-5). The grounding ends 34-1 of all the temperature sensors 34 in the same column group are connected to the same ground wire 18 (such as one of the ground wires 18-1, 18-2, 18-3, 18-4, 18-5). Each row group of serially arranged temperature sensors 34 is respectively connected in series with a bidirectional switching switch 55 (such as bidirectional switching switches 55-1, 55-2, 55-3 or 55-4) and a voltage-dividing resistor 53 (such as voltage-dividing resistors R1, R2, R3 or R4) at the DC power supply VCC end, and the voltage-dividing resistor 53 (such as voltage-dividing resistors R1, R2, R3 or R4) is closer to the DC power supply VCC end than the bidirectional switching switch 55 (such as bidirectional switching switches 55-1, 55-2, 55-3 or 55-4). Each ground wire 18 is respectively connected in series with a control switch 54 (such as control switches 54-1, 54-2, 54-3, 54-4 or 54-5).

[0079] In this embodiment, when a temperature detection unit 35 is configured in each electrode unit 33 for temperature detection, the above circuit design is adopted to reduce the number of wires of the first cable 15, avoid the cable from becoming thicker and the softness of the cable from becoming harder, thereby increasing the difficulty of cable fixing; at the same time, avoid the increase in the number of wires of the first cable 15 from affecting the adhesion effect between the electrode patch 13 and the corresponding body surface of the patient's tumor site. The ground wires 18, the two-purpose signal lines 19 and the rectifying ground wires (not labeled) embedded in the substrate 31 are a total of 10 circuit lines. Specifically, in this embodiment, there are 5 circuit lines of the ground wires 18 embedded in the substrate 31, 4 circuit lines of the two-purpose signal lines 19, and 1 circuit line of the rectifying ground wires (not labeled). The number of the ground wires 18 is related to the number of column groups N of the electrode units 33, and is greater than or equal to the number of column groups of the electrode units 33, and N is a positive integer. The number of the two-purpose signal lines 19 is related to the number of row groups M of the electrode units 33, and is greater than or equal to the number of row groups of the electrode units 33, and M is a positive integer. The number of circuit lines L embedded in the substrate 31 of the electrode patch 13 is equal to the sum of the number of the rectifying ground wires (not labeled), the number of the ground wires 18 and the number of the two-purpose signal lines 19. In this embodiment, the number of the ground wires 18 is equal to the number of column groups N of the electrode units 33; the two-purpose signal lines 19 are equal to the number of row groups M of the electrode units 33.

[0080] A plurality of electrode units 33 are arranged at intervals on the substrate 31 in a substantially two-dimensional array form. Such as Figure 2As shown in the figure, the electrode sheet 13 in this embodiment includes 20 electrode units 33. The 20 electrode units 33 are arranged in a four-row and six-column array. Both the first row and the fourth row have four electrode units 33, and both the second row and the third row have six electrode units 33. The four electrode units 33 in each row of the first row and the fourth row are located in the columns from the second column to the fifth column, and the six electrode units 33 in each row of the second row and the third row are located in the columns from the first column to the sixth column. The five electrode units 33 located in the second and third columns of the first row and the first, second, and third columns of the second row are divided into region 1. The five electrode units 33 located in the fourth and fifth columns of the first row and the fourth, fifth, and sixth columns of the second row are divided into region 2. The five electrode units 33 located in the first, second, and third columns of the third row and the second and third columns of the fourth row are divided into region 3. The five electrode units 33 located in the fourth, fifth, and sixth columns of the third row and the fourth and fifth columns of the fourth row are divided into region 4. Each region (1-4) corresponds to a row group. In some other embodiments, the 20 electrode units 33 can also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 13 can also have other numbers of electrode units 33. In short, the implementation of this application is not limited by the number and arrangement form of the electrode units 33 of the electrode sheet 13.

[0081] Each electrode unit 33 can apply an alternating electric signal, and thus the paired electrode sheets 13 are used to apply an alternating electric field to the tumor site of the patient. Optionally, the electrode unit 33 includes a dielectric element. The dielectric element can be a ceramic sheet or a polymer dielectric layer made of a polymer material. Each temperature detection unit 35 is provided corresponding to an electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be disposed at any position of the corresponding electrode unit 33, such as Figure 3 and Figure 4As shown, in this embodiment, each electrode unit 33 is provided with a perforation 331, and the perforation 331 is adapted to mount a temperature detection unit 35. For example, the middle of each electrode unit 33 has a perforation 331 penetrating therethrough, and each perforation 331 of each electrode unit 33 houses a corresponding temperature detection unit 35. Each temperature detection unit 35 includes a temperature sensor 34. A diode 36 is provided for each temperature detection unit 35 corresponding to the electrode plate 13. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1, and the diode 36 has an anode 36-1 and a cathode 36-2. The anode 36-1 of each diode 36 is connected to the ground terminal 34-1 of the corresponding temperature sensor 34. After the cathodes 36-2 of the diodes 36 corresponding to each column group are connected together, they are connected to the ground pin GND through the corresponding control switch 54. Specifically, the anode 36-1 of the diode 36 is connected to the ground terminal 34-1 of the temperature sensor 34, the cathode 36-2 of the diode 36 is connected to the ground pin GND through the corresponding control switch 54, the ground terminal 34-1 of the temperature sensor 34 serves as the ground terminal 35-1 of the temperature detection unit 35, and the signal terminal 34-2 of the temperature sensor 34 serves as the signal terminal 35-2 of the temperature detection unit 35. The temperature sensor 34 can be a thermistor or other temperature sensors other than thermistors. Each temperature sensor 34 corresponds to a diode 36, and the diode 36 is connected in series with the temperature sensor 34 of the same electrode unit 33, which can prevent the reverse inflow of current to prevent the detection signal from other electrode units 33 from affecting the temperature sensor 34.

[0082] As Figure 3As shown, the electrode sheet 13 of this embodiment includes five ground wires 18, and each ground wire 18 is used to ground the ground terminals 35-1 of the temperature detection units 35 in the same column group. The five ground wires 18 of the electrode sheet 13 are respectively the first ground wire 18-1, the second ground wire 18-2, the third ground wire 18-3, the fourth ground wire 18-4, and the fifth ground wire 18-5. Among the five column groups of the electrode sheet 13, the first column group includes the electrode units 33-1, 33-6, 33-11, and 33-16, the second column group includes the electrode units 33-2, 33-7, 33-12, and 33-17, the third column group includes the electrode units 33-3, 33-8, 33-13, and 33-18, the fourth column group includes the electrode units 33-4, 33-9, 33-14, and 33-19, and the fifth column group includes the electrode units 33-5, 33-10, 33-15, and 33-20.Specifically, the first ground wire 18-1 is used to ground the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group respectively; the second ground wire 18-2 is used to ground the two temperature detection units 35 connected in series in the electrode units 33-1 and 33-2, the two temperature detection units 35 connected in series in the electrode units 33-6 and 33-7, the two temperature detection units 35 connected in series in the electrode units 33-11 and 33-12, and the two temperature detection units 35 connected in series in the electrode units 33-16 and 33-17; the third ground wire 18-3 is used to ground the three temperature detection units 35 connected in series from the electrode unit 33-1 to the electrode unit 33-3, the three temperature detection units 35 connected in series from the electrode unit 33-6 to the electrode unit 33-8, the three temperature detection units 35 connected in series from the electrode unit 33-11 to the electrode unit 33-13, and the three temperature detection units 35 connected in series from the electrode unit 33-16 to the electrode unit 33-18; the fourth ground wire 18-4 is used to ground the four temperature detection units 35 connected in series from the electrode unit 33-1 to the electrode unit 33-4, the four temperature detection units 35 connected in series from the electrode unit 33-6 to the electrode unit 33-9, the four temperature detection units 35 connected in series from the electrode unit 33-11 to the electrode unit 33-14, and the four temperature detection units 35 connected in series from the electrode unit 33-16 to the electrode unit 33-19; the fifth ground wire 18-5 is used to ground the five temperature detection units 35 connected in series from the electrode unit 33-1 to the electrode unit 33-5, the five temperature detection units 35 connected in series from the electrode unit 33-6 to the electrode unit 33-10, the five temperature detection units 35 connected in series from the electrode unit 33-11 to the electrode unit 33-15, and the five temperature detection units 35 connected in series from the electrode unit 33-16 to the electrode unit 33-20. It should be noted that these ground wires 18 can be selectively closed or disconnected, for example, by connecting each ground wire 18 in series with a control switch 54 respectively, that is, the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33 in each column group are commonly connected to the ground pin GND through a control switch 54, which will be described in detail below. Combine. Figure 4 , after the ground terminal 34-1 of the corresponding temperature sensor 34 in each column group is connected to the anode 36-1 of the corresponding diode 36, they are connected together through the cathode 36-2 of the corresponding diode 36. In short, each ground wire 18 shorts the ground terminals 35-1 of the temperature detection units 35 corresponding to all the electrode units 33 in each column group through the diode 36 and grounds them.

[0083] Such as Figure 3As shown, the electrode sheet 13 of this embodiment further includes 4 two-purpose signal lines 19. One end of each two-purpose signal line 19 is respectively connected to the fixed end 3 of the rectifying and switching unit 16 corresponding to each row group, and the other end is connected to the adapter 20 for receiving temperature detection signals and transmitting alternating current signals. Specifically, the 4 two-purpose signal lines 19 of the electrode sheet 13 include a first two-purpose signal line 19-1, a second two-purpose signal line 19-2, a third two-purpose signal line 19-3, and a fourth two-purpose signal line 19-4. Five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 are respectively connected to the second switching end 2 of the corresponding rectifying and switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16; five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 are respectively connected to the second switching end 2 of the corresponding rectifying and switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16; five electrode units 33 from electrode unit 33-11 to electrode unit 33-15 are respectively connected to the second switching end 2 of the corresponding rectifying and switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-11 to electrode unit 33-15 are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16; five electrode units 33 from electrode unit 33-16 to electrode unit 33-20 are respectively connected to the second switching end 2 of the corresponding rectifying and switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-16 to electrode unit 33-20 are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16. In short, each two-purpose signal line 19 is respectively connected to each electrode unit 33 in the same row group through the corresponding rectifying and switching unit 16, and is connected in series with the temperature detection unit 35 corresponding to each electrode unit 33 in the same row group. It should be noted that these two-purpose signal lines 19 can selectively transmit alternating current signals or temperature detection electrical signals, which can be achieved by cooperating each two-purpose signal line 19 with the corresponding rectifying and switching unit 16 and multiplexing switching unit.That is to say, in each row group, the temperature detection units 35 are connected in series to the corresponding rectifying and switching unit 16, and then jointly connected to the multiplexing and switching unit through a dual-purpose signal line 19. The multiplexing and switching unit includes a plurality of bidirectional switching switches 55, such as bidirectional switching switch 55-1, bidirectional switching switch 55-2, bidirectional switching switch 55-3, and bidirectional switching switch 55-4. Each bidirectional switching switch 55 has a fixed terminal (not labeled) electrically connected to the corresponding dual-purpose signal line 19, a terminal 1 (i.e., the temperature sampling point) electrically connected to the ADC unit 52 in the adapter 20, and a terminal 2 electrically connected to the alternating power supply line 57. The multiplexing and switching unit is configured to switch the dual-purpose signal line 19 to be connected to the temperature sampling point (not labeled) or the alternating power supply line 57. Among them, when any one of the dual-purpose signal lines 19 is connected to the corresponding temperature sampling point (not labeled), through the linkage of the rectifying and switching unit 16 corresponding to the dual-purpose signal line 19, the first switching terminal 1 of the rectifying and switching unit 16 corresponding to the dual-purpose signal line 19 is connected to the fixed terminal 3, and by sequentially closing the control switches 54 corresponding to each column group, the analog temperature signals detected by the temperature detection units 35 in the row group corresponding to the dual-purpose signal line 19 are sequentially sampled based on the corresponding temperature sampling point (not labeled); when any one of the dual-purpose signal lines 19 is connected to the alternating power supply line 57, through the linkage of the rectifying and switching unit 16 corresponding to the dual-purpose signal line 19, the second switching terminal 2 of the rectifying and switching unit 16 corresponding to the dual-purpose signal line 19 is connected to the fixed terminal 3, so that the alternating current signals are applied to each electrode unit 33 in the row group corresponding to the dual-purpose signal line 19 based on the alternating power supply line 57.

[0084] The multiple ground wires 18, the multiple dual-purpose signal lines 19, and the rectifying ground wire (not labeled) are all conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multiple ground wires 18, the multiple dual-purpose signal lines 19, and the rectifying ground wire (not labeled) embedded in the substrate 31 are respectively and electrically connected to the corresponding wires (not shown) in the first cable 15 one by one.

[0085] The tumor electric field treatment system 100 of this embodiment includes at least a pair of the above-mentioned electrode plates 13, an adapter 20 electrically connected to the electrode plates 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode plates 13 and the electric field generator 30. The electric field generator 30 provides an alternating current signal to the multiple electrode units 33 of the electrode plates 13 via the adapter 20 and the dual-purpose signal lines 19 of the electrode plates 13, or is used to receive the temperature detection signals output by the temperature detection units 35 corresponding to the multiple electrode units 33. The adapter 20 conveys the alternating current signal generated by the electric field generator 30 to the dual-purpose signal lines 19 of the electrode plates 13, and is also configured to receive the temperature detection signals output by the multiple dual-purpose signal lines 19 of the electrode plates 13.

[0086] Reference Figure 3 As shown, the adapter 20 includes: a first controller 51, multiple groups of ADC units 52 connected to the first controller 51, multiple groups of voltage dividing resistors 53 and multiple groups of control switches 54 corresponding to the multiple groups of ADC units 52 one by one, multiple groups of bidirectional switching switches 55 connected to the multiple groups of ADC units 52 one by one, a first communication unit 56, alternating current power lines 57 connected to each group of bidirectional switching switches 55 one by one, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple groups of ADC units 52 at the same time. The first power module 58 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (not labeled), and the multiple circuit lines (not labeled) are respectively electrically connected to multiple ground lines 18, multiple dual-purpose signal lines 19, and a rectifying ground line (not labeled) in the substrate 31 of the corresponding electrode plate 13 through the first cable 15 of the corresponding electrode plate 13 one by one. The multiple circuit lines (not labeled) include multiple alternating current power lines 57 that respectively transmit alternating current signals to the corresponding electrode plates 13 and are electrically connected to the multiple dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plates 13, multiple circuit lines (not labeled) that are respectively electrically connected to the multiple dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plates 13 one by one and are used to supply power to each temperature detection unit 35 of the electrode plate 13 or transmit the temperature detection signal of the electrode plate 13, multiple circuit lines (not labeled) that are respectively electrically connected to the multiple ground lines 18 in the substrate 31 of the corresponding electrode plates 13 one by one, and a circuit line that is electrically connected to the ground line of each rectifying switching unit 16. The number L of circuit lines of the adapter 20 electrically connected to an electrode plate 13 is equal to the sum of the number of rows M and the number of columns N of the electrode units 33 of the electrode plate 13 plus one; the number H of circuits of the adapter 20 electrically connected to X electrode plates 13 is X times the number of circuit lines of it electrically connected to a single electrode plate 13, that is, H = XL = X*(M + N + 1). The number of groups of the control switches 54 and the number of groups of the bidirectional switching switches are both related to the number of electrode plates 13. The number of groups of the control switches 54 is the same as the number of groups of the bidirectional switching switches, and is not less than the number of electrode plates 13. Optionally, the number of groups of the control switches 54 and the bidirectional switching switches are both the same as the number of electrode plates 13. The following takes the electrical connection between an electrode plate 13 with 20 electrode units 33 and the adapter 20 as an example for detailed description.

[0087] Each set of control switches 54 is provided with a plurality of control switches 54. The plurality of control switches 54 are respectively connected into the adapter 20 and are respectively electrically connected to circuit lines (not labeled) corresponding one by one to the multiple ground wires 18 of a corresponding electrode plate 13, and are configured to control the conduction or disconnection between the multiple ground wires 18 and the ground pin GND. The circuit lines (not labeled) of the multiple ground wires 18 that are respectively and electrically connected to the electrode plate 13 are grounded at one end close to the control switch 54. The number of control switches 54 in each set of control switches 54 is related to the number of ground wires 18 of the substrate 31 of the corresponding electrode plate 13, and in this embodiment, the two are equal. As Figure 3 shown, in this embodiment, the multiple control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3, a fourth control switch 54-4, and a fifth control switch 54-5. The multiple control switches 54 in the same group respectively control the closing or opening of the corresponding ground wires 18 of the same electrode plate 13. The first control switch 54-1 is used to control the closing or opening of the first ground wire 18-1 of the corresponding electrode plate 13, and further can cooperate with the corresponding group of bidirectional switching switches 55 and rectification switching units 16 to control the power-on and power-off of each temperature detection unit 35 corresponding to the four electrode units 33, namely the electrode unit 33-1, the electrode unit 33-6, the electrode unit 33-11, and the electrode unit 33-16, in the first column group of the electrode plate 13; the second control switch 54-2 is used to control the closing or opening of the second ground wire 18-2 of the electrode plate 13, and further can cooperate with the corresponding group of bidirectional switching switches 55 and rectification switching units 16 to control the power-on and power-off of the temperature detection units 35 corresponding to multiple electrode units 33 (the multiple electrode units 33 can be respectively: the electrode unit 33-1 and the electrode unit 33-2, the electrode unit 33-6 and the electrode unit 33-7, the electrode unit 33-11 and the electrode unit 33-12, the electrode unit 33-16 and the electrode unit 33-17) in the first column group and the second column group of the electrode plate 13; the third control switch 54-3 is used to control the closing or opening of the third ground wire 18-3 of the electrode plate 13, and further can cooperate with the corresponding group of bidirectional switching switches 55 and rectification switching units 16 to control the power-on and power-off of each temperature detection unit 35 corresponding to multiple electrode units 33 (the multiple electrode units 33 can be respectively: the electrode units 33-1 to 33-3, the electrode units 33-6 to 33-8, the electrode units 33-11 to 33-13, the electrode units 33-16 to 33-18) in the first column group, the second column group, and the third column group of the electrode plate 13; the fourth control switch 54-4 and the fifth control switch 54-5 are the same. The above control switches 54 can be mechanical switches, such as relays. The control switches 54 can also be electronic switches, and each control switch 54 can be opened and closed through an additional first controller 51.

[0088] In this embodiment, multiple groups of control switches 54 are all electronic switches. The first controller 51 is communicatively connected to the multiple groups of control switches 54 and is used to sequentially and cyclically control the opening and closing states of the multiple control switches 54 in each group of control switches 54, so as to sequentially and individually conduct each of the multiple ground wires 18 of the corresponding electrode plate 13 and cooperate with the switching of the corresponding bidirectional switching switch 55 and the rectifying switching unit 16 to collect the temperatures of the patient's body surface detected by all the temperature detection units 35 on the electrode plate 13. The number of control switches 54 in each group is not less than the number of ground wires 18 of the substrate 31 of the corresponding electrode plate 13. In this embodiment, the number of control switches 54 in each group is the same as the number of ground wires 18 of the corresponding electrode plate 13.

[0089] Each multiplexing switching unit is provided with multiple bidirectional switching switches 55. The multiple bidirectional switching switches 55 are respectively connected into the adapter 20 and are respectively electrically connected to circuit lines (not labeled) corresponding to the multiple dual-purpose signal lines 19 of a corresponding electrode plate 13 one by one. The number of bidirectional switching switches 55 in each multiplexing switching unit is related to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode plate 13, and is greater than or equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode plate 13. In this embodiment, the two are equal. Each bidirectional switching switch 55 has two ends labeled 1 and 2. The 1 ends of the multiple bidirectional switching switches 55 in the same group are the temperature sampling points, which are respectively and electrically connected to the corresponding detection channels of the multiple detection channels of a corresponding group of ADC units 52 one by one. The 2 ends of each bidirectional switching switch 55 in the same group are all electrically connected to the corresponding same alternating power supply line 57 and are configured to control the multiple dual-purpose signal lines 19 to be connected to the corresponding alternating power supply line 57 to transmit alternating current signals or to be connected to the corresponding detection channels of the corresponding group of ADC units 52 to receive the temperature detection signals output by the temperature detection units 35.

[0090] Such as Figure 3As shown, taking an electrode sheet 13 electrically connected to the adapter 20 as an example, in this embodiment with 20 electrode units 33, the plurality of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3 and a fourth bidirectional switch 55-4. The plurality of bidirectional switches 55 in the same group respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of a corresponding one of the multiplexed dual-purpose signal lines 19 of the same electrode sheet 13. Specifically, the first bidirectional switch 55-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, and then cooperates with the rectifier switching unit 16 corresponding to the first row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-1 to the electrode unit 33-5 in the first row group, or the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-1 to the electrode unit 33-5 in the first row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the first row of electrode units 33-1 to the electrode unit 33-5 to transmit the alternating electric signal to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52. The second bidirectional switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, and then cooperates with the rectifier switching unit 16 corresponding to the second row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-6 to the electrode unit 33-10 in the second row group, or conducts with the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-6 to the electrode unit 33-10 in the second row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the second row electrode unit 33-6 to the electrode unit 33-10 to transmit the alternating electric signal to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52;The third bidirectional switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13 between transmitting alternating electric signals and transmitting temperature detection signals, and then cooperates with the rectifier switching unit 16 corresponding to the third row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-11 to the electrode unit 33-15 in the third row group of the electrode sheet 13, or conducts with the signal end 35-2 of each temperature detection unit corresponding to the electrode unit 33-11 to the electrode unit 33-15 in the third row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the third row of electrode units 33-11 to the electrode unit 33-15 to transmit alternating electric signals to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52; The four bidirectional switching switches 55-4 are used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13 between transmitting alternating electrical signals and transmitting temperature detection signals, and then work together with the rectifier switching unit 16 corresponding to the fourth row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group of the electrode sheet 13, or to conduct with the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group, and cooperate with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the fourth row of electrode units 33-16 to the electrode unit 33-20 to transmit alternating electrical signals to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52. When two ends of each group of two-way switches are turned on and one end is turned off, and the second switching end 2 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, an alternating electrical signal can be transmitted to each electrode unit 33 in the corresponding row group of the corresponding electrode sheet 13. When one end of each two-way switch 55 in each group of two-way switches 55 is turned on and two ends are turned off in sequence and in time-sharing, and two ends of the remaining two-way switches 55 are turned on and one end is turned off, and the first switching end 1 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, it can cooperate with each control switch 54 in the corresponding group of control switches 54 to transmit the temperature detection signal collected by the temperature detection unit 35 of each electrode unit 33 on the electrode sheet 13 in time-sharing. The above-mentioned two-way switch 55 can be a mechanical switch, such as a relay. The two-way switch can also be an electronic switch, and each two-way switch 55 can be switched by the first controller 51 of the adapter 20. ;

[0091] In this embodiment, the plurality of sets of two-way switches 55 are all electronic switches. The first controller 51 is in communication connection with the plurality of sets of two-way switches 55, and is used to control the plurality of two-way switches 55 in each set of two-way switches 55 to switch between their respective ends 1 and 2, and to coordinate the closing or opening of the corresponding control switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 35 on the electrode sheet 13 or transmit an alternating electrical signal to the patient.

[0092] In some embodiments of the present application, Figure 3 As shown, the rectifying switching unit 16 includes a rectifying circuit 161 and a controllable switch 162. The rectifying circuit 161 is, for example, a rectifying bridge, which is configured to rectify the alternating current provided by the alternating power line 57 and supply it to the controllable switch 162 when the dual-purpose signal line 19 is connected to the alternating power line 57, so that the rectifying switching unit 16 switches the second switching end to be connected to the fixed end.

[0093] Specifically, the rectifier circuit 161 has terminals 1-4, terminal 1 of the rectifier circuit 161 is connected to the dual-purpose signal line 19 corresponding to the corresponding row group electrode unit 33 and terminal 3 of the controllable switch 162, terminals 2 and 4 of the rectifier circuit 161 are used to provide power to the controllable switch 162, terminal 3 of the rectifier circuit 161 is connected to the ground pin GND through a rectifier ground line (unnumbered), multiple electrode units 33 in the same row group are connected in parallel to terminals 2 of the controllable switch 162, multiple temperature sensors 34 in the same row group are connected in series, and a signal terminal 34-2 at the end of each row group is electrically connected to terminal 1 of the controllable switch 162. As an example, the controllable switch 162 can be a relay, an electronic switch, etc.

[0094] Among them, the controllable switch 162 is a normally closed switch, that is, it is turned on at one end and connected to the temperature sensor 34 by default. The controllable switch 162 is linked with the corresponding two-way switching switch 55. When the corresponding two-way switching switch 55 is switched to its own one end, the controllable switch 162 is also switched to its own one end, and the temperature sensor 34 located in the same row group is connected to the corresponding dual-purpose signal line 19, the connection between the electrode unit 33 in the corresponding row group and the corresponding dual-purpose signal line 19 is disconnected, and the corresponding control switch 54 is opened and closed to obtain the analog temperature signal detected by the corresponding temperature sensor 34; when the corresponding two-way switching switch 55 is switched to its own two ends, the AC signal is rectified by the rectifying circuit 161 to provide power, which will trigger the controllable switch 162. The controllable switch 162 is also switched to its own two ends, and the electrode unit 33 located in the same row group is connected to the corresponding dual-purpose signal line 19, the connection between the temperature sensor 34 in the corresponding row group and the corresponding dual-purpose signal line 19 is disconnected, and all the control switches 54 are disconnected to transmit the AC signal to the electrode unit 33 of the corresponding row group.

[0095] In this embodiment, each group of ADC units 52 is electrically connected to one end of a plurality of bidirectional switching switches 55 in the corresponding multiplexing and switching unit through a plurality of circuit lines (not labeled) in the adapter 20, and is configured to receive the temperature detection signals transmitted by the multi-purpose signal lines 19 of the corresponding electrode plates 13, and convert the temperature detection signals from analog signals into digital temperature signals. As Figure 3 shown, each group of ADC units 52 includes a total of 4 detection channels A, B, C, and D, namely the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. Each detection channel A, B, C, and D is used to connect to a corresponding one of the multi-purpose signal lines 19 in the multi-purpose signal line 19 through the corresponding bidirectional switching switch 55. Specifically, the first detection channel A is connected to the first multi-purpose signal line 19-1 through one end of the first bidirectional switching switch 55-1, the second detection channel B is connected to the second multi-purpose signal line 19-2 through one end of the second bidirectional switching switch 55-2, the third detection channel C is connected to the third multi-purpose signal line 19-3 through one end of the third bidirectional switching switch 55-3, and the fourth detection channel D is connected to the fourth multi-purpose signal line 19-4 through one end of the fourth bidirectional switching switch 55-4. Each detection channel A, B, C, and D is used to receive the temperature detection signals collected by the temperature detection unit 35 corresponding to the electrode unit 33 to which the corresponding multi-purpose signal line 19 is connected. In addition, each detection channel A, B, C, and D is connected to a first power supply module 58 for providing a detection voltage to this detection channel A, B, C, and D through a corresponding voltage dividing resistor 53 in the adapter 20, and the first power supply module 58 provides direct current electricity.

[0096] In this embodiment, the first communication unit 56 is configured to obtain the digital temperature signals output by multiple groups of ADC units 52 and send the digital temperature signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the alternating current signal provided to the multiple electrode units 33 of the electrode plate 13 according to the received digital temperature signals. Exemplarily, when any one of the multiple received digital temperature signals exceeds a preset threshold, it means that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode plate 13 exceeds the preset temperature threshold (such as 41 °C, 42 °C, etc.). At this time, the voltage of the alternating current signal output by the electric field generator 30 can be appropriately reduced to avoid the temperature of the electrode unit 33 of the electrode plate 13 being too high when applying the alternating current signal, causing low-temperature burns to the patient's skin. The above preset temperature threshold and preset threshold can be determined according to the human safety threshold. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital temperature signals converted by multiple groups of ADC units 52. In this embodiment, the preset temperature threshold can be a value within 36 °C - 45 °C.

[0097] Reference Figure 5 and Figure 6 , in this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, multiple groups of ADC units 52, and the first communication unit 56 of the adapter 20. A first connector 60 is connected between each electrode plate 13 and the adapter 20, and the first connector 60 is adapted to connect the corresponding electrode plate 13 to the adapter 20. As Figure 1 shown, the first connector 60 includes a first plug 61 provided at one end of the first cable 15 away from the electrode plate 13 and a first socket 62 provided on the adapter 20. The first plug 61 and the first socket 62 are push-type spring connectors, that is, the first connector 60 connects the adapter 20 and the electrode plate 13 in a plug-in manner. Each first cable 15 has 4 wires electrically connected to the corresponding bidirectional switch 55 in the corresponding group of bidirectional switches 55, 5 wires electrically connected to the corresponding control switch 54 in the corresponding group of control switches 54, and 1 ground wire connected to the rectifier switching unit 16. That is, each first connector 60 is electrically connected to a corresponding group of bidirectional switches 55, a corresponding group of control switches 54, and the corresponding ground wire of the adapter 20 through 10 wires, and is connected to the electric field generator 30 through a corresponding alternating power supply line 57 of the adapter 20.

[0098] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is adapted to connect the electric field generator 30 to the adapter 20. As Figure 1As shown, the adapter 20 further includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 provided at one end of the second cable 25 away from the first controller 51 and a second socket 72 provided on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, that is, the second connector 70 connects the adapter 20 and the electric field generator 30 in the form of a connector. Each of the first connectors 60, such as X1, Y1, X2, and Y2, is connected to the second connector 70 through a corresponding alternating current power line 57. The first connectors 60, such as X1, Y1, X2, and Y2, are also respectively connected to a corresponding group of control switches 54 and a corresponding group of ADC units 52. Among them, each first connector 60 is respectively connected to the second connector 70 and a corresponding group of ADC units 52 through a corresponding group of bidirectional changeover switches 55. The second cable 25 has 8 wires, which include 4 wires respectively and electrically connected to the corresponding alternating current power lines 57 one by one and used for transmitting alternating current signals, namely wires 1 to 4, 1 wire electrically connected to the data receiving line RX of the first communication unit 56, 1 wire electrically connected to the data sending line TX of the first communication unit 56, 1 wire electrically connected to the VCC power line of the first power module 58, and 1 wire electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 through the data receiving line RX and the data sending line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58. The GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded. The VCC pin of the second connector 70 is also connected to the corresponding group of voltage dividing resistors 53 and the corresponding group of ADC units 52 through the VCC power line of the first power module 58.

[0099] Reference Figure 5 and Figure 7, the electric field generator 30 includes: a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38, and a set of power supply switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to and powers the second controller 37 and the AC signal generator 39 respectively. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and electrically connected to the wire 6 of the second connector 70 through its data sending line TX, so as to realize information interaction between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of power supply switches 40 at the same time. The second controller 37 is configured to control the opening and closing of each power supply switch 40 in the set of power supply switches 40 and adjust the relevant parameters of the alternating electric signal applied by the AC signal generator 39 according to the relevant digital temperature signal received from the adapter 20 by the second communication unit 38. The AC signal generator 39 is electrically connected to the wires 1 to 4 for transmitting the alternating electric signal of the second connector 70 through a set of power supply switches 40. The set of power supply switches 40 includes a plurality of power supply switches 40, and the plurality of power supply switches 40 are arranged in one-to-one correspondence with a plurality of electrode plates 13. Each power supply switch 40 is electrically connected to one of the wires 1, 2, 3, 4 for transmitting the alternating electric signal in the second connector 70 through an AC power line 41-1, 41-2, 41-3, 41-4 and is electrically connected to the corresponding electrode plate 13 through the corresponding wires 1, 2, 3, 4 of the second connector 70 to deliver the alternating electric signal to each electrode plate 13. The AC signal generator 39 is electrically connected to the set of power supply switches 40 through a plurality of AC power lines 41. Specifically, the number of the power supply switches 40 of the electric field generator 30 is related to the number of the electrode plates 13. In this embodiment, the number of the power supply switches 40 is equal to the number of the electrode plates 13 and both are 4. The power supply switches 40 include a first power supply switch 40-1, a second power supply switch 40-2, a third power supply switch 40-3, and a fourth power supply switch 40-4 that are respectively electrically connected to the wires 1 to 4 of the second connector 70 in one-to-one correspondence.One end of the first power supply switch 40-1 is electrically connected to the AC signal generator 39 through the AC power line (not labeled) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting the AC electric signal in the second connector 70 through an AC power line 41-1, and is electrically connected to the AC power line 57 at the port X1 of the adapter 20 through the wire 1 of the second connector 70. The AC power line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 13 to control whether the AC signal generator 39 delivers an AC electric signal to the electrode plate 13 electrically connected to the port X1 of the adapter 20. One end of the second power supply switch 40-2 is electrically connected to the AC signal generator 39 through the AC power line (not labeled) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting the AC electric signal in the second connector 70 through an AC power line 41-2, and is electrically connected to the AC power line 57 at the port Y1 of the adapter 20 through the wire 2 of the second connector 70. The AC power line 57 at the port Y1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode plate 13 to control whether the AC signal generator 39 delivers an AC electric signal to the electrode plate 13 electrically connected to the port Y1 of the adapter 20. One end of the third power supply switch 40-3 is electrically connected to the AC signal generator 39 through the AC power line (not labeled) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting the AC electric signal in the second connector 70 through an AC power line 41-3, and is electrically connected to the AC power line 57 at the port X2 of the adapter 20 through the wire 3 of the second connector 70. The AC power line 57 at the port X2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode plate 13 to control whether the AC signal generator 39 delivers an AC electric signal to the electrode plate 13 electrically connected to the port X2 of the adapter 20. One end of the fourth power supply switch 40-4 is electrically connected to the AC signal generator 39 through the AC power line (not labeled) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 4 for transmitting the AC electric signal in the second connector 70 through an AC power line 41-4, and is electrically connected to the AC power line 57 at the port Y2 of the adapter 20 through the wire 4 of the second connector 70. The AC power line 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode plate 13 to control whether the AC signal generator 39 delivers an AC electric signal to the electrode plate 13 electrically connected to the port Y1 of the adapter 20.

[0100] The following will refer to Figures 3 to 5The working principle of the tumor electric field treatment system 100 of this embodiment is introduced in detail.

[0101] Specifically, when it is necessary to detect the temperature at each electrode unit 33 of a certain electrode plate 13, the second controller 37 of the electric field generator 30 controls the corresponding power supply switch 40 to disconnect the alternating current signal applied to the electrode plate 13. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls one of the multiple bidirectional switching switches 55 of a multiplexing switching unit electrically connected to the electrode plate 13, so that the 1 end of the bidirectional switching switch 55 is turned on and the 2 end is turned off. The VCC provided by the first power supply module 58 powers the corresponding temperature detection unit 35, and the contact 3 of the controllable switch 162 in the rectification switching unit 16 linked to the bidirectional switching switch 55 is connected to the contact 1; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each control switch 54 in a group of control switches 54 electrically connected to the electrode plate 13 to be sequentially turned on in time division. At this time, through the detection channels of the multiple detection channels of a group of ADC units 52 corresponding to the electrode plate 13, the detection channel turned on at the 1 end of the bidirectional switching switch 55, the combined temperature detection signals detected by the first temperature detection unit 35 or multiple temperature detection units 35 in the corresponding row group can be sampled in sequence. The above temperature detection signals can be characterized by voltage values. Only 1 of the 5 control switches 54 in a group of control switches 54 corresponding to the electrode plate 13 can be turned on at the same time, and the other 4 are turned off. Only one of the 4 bidirectional switching switches 55 in the multiplexing switching unit corresponding to the group of ADC units 52 is switched to its 1 end, and the rest are switched to its 2 end, so that one of the all-purpose signal lines 19 of each path of the electrode plate 13 is electrically connected and turned on corresponding to a detection channel (A, B, C or D) of the corresponding ADC unit 52. With such a setting, the group of ADC units 52 can collect the voltage value of the first temperature detection unit 35 in the same row group short-circuited with the grounded wire 18 corresponding to the turned-on control switch 54, or the voltage values of the first and second temperature detection units 35 in series, or the voltage values of the first to third temperature detection units 35 in series, or the voltage values of the first to fourth temperature detection units 35 in series, or the voltage values of the first to fifth temperature detection units 35 in series.

[0102] Further, when the first control switch 54-1 is closed, the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all open, and the first bidirectional switch 55-1 is switched to its terminal 1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed terminal 3, the temperature detection unit 35 corresponding to the electrode unit 33-1 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the group of ADC units 52. Since only the signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is conductively grounded, and the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode unit 33-2, the electrode unit 33-3, the electrode unit 33-4, and the electrode unit 33-5 are all open, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-1. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-1 operates effectively on the first detection channel A of the group of ADC units 52, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1, realizing accurate temperature detection at the electrode unit 33-1.

[0103] When the second control switch 54-2 is closed, the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all open, and the first bidirectional switch 55-1 is switched to its terminal 1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed terminal 3, the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. On the first detection channel A of this group of ADC units 52, the signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited. The temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are connected in series. Since only the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-2 is conductively grounded, and the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-3, 33-4, and 33-5 are all open, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, it will not affect the resistance value of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 operate effectively on the first detection channel A of this group of ADC units 52. The temperature detection signal (voltage value) collected by the first detection channel A is the sum of the voltage values of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. Subtracting the voltage value of the temperature detection unit 35 corresponding to the aforementioned electrode unit 33-1, the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-2 can be obtained, realizing the accurate temperature detection at the electrode unit 33-2.

[0104] Similarly, when the third control switch 54-3 is closed, the first control switch 54-1, the second control switch 54-2, the fourth control switch 54-4, and the fifth control switch 54-5 are all open, and the first bidirectional switch 55-1 is switched to its terminal 1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed terminal 3, the voltage value detected on the first detection channel A of this group of ADC units 52 is the sum of the voltage values of the temperature detection units 35 corresponding to the electrode units 33-1, 33-2, and 33-3. Subtracting the sum of the voltage values of the temperature detection units 35 corresponding to the aforementioned electrode units 33-1 and 33-2, the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-3 can be obtained, realizing the accurate temperature detection at the electrode unit 33-3.

[0105] And so on. When the fourth control switch 54-4 is closed, the first control switch 54-1, the second control switch 54-2, the third control switch 54-3, and the fifth control switch 54-5 are all open, and the first bidirectional switch 55-1 is switched to its terminal 1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and the first switching end 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed end 3, accurate temperature detection at the electrode unit 33-4 can be achieved; when the fifth control switch 54-5 is closed, the first control switch 54-1, the second control switch 54-2, the third control switch 54-3, and the fourth control switch 54-4 are all open, and the first bidirectional switch 55-1 is switched to its terminal 1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and the first switching end 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed end 3, accurate temperature detection at the electrode unit 33-5 can be achieved.

[0106] Thus, the temperature detection signals of each electrode unit 33 in the first row group can be sequentially collected through the first detection channel A.

[0107] Similarly, when the first control switch 54-1 is closed, the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all open, and the second bidirectional changeover switch 55-2 is switched to its terminal 1, the first bidirectional changeover switch 55-1, the third bidirectional changeover switch 55-3, and the fourth bidirectional changeover switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the second row group is connected to the fixed terminal 3, the temperature detection unit 35 corresponding to the electrode unit 33-6 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B in the group of ADC units 52. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is conductively grounded, while the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-7, 33-8, 33-9, and 33-10 are all open, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-6 will not be affected. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-6 operates effectively on the second detection channel B of the group of ADC units 52, and the temperature detection signal (voltage value) collected by the second detection channel B is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6, achieving accurate temperature detection at the electrode unit 33-6.

[0108] When the second control switch 54-2 is closed, the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all open, and the second two-way switching switch 55-2 is switched to its terminal 1, the first two-way switching switch 55-1, the third two-way switching switch 55-3, and the fourth two-way switching switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectifying switching unit 16 corresponding to the second row group is connected to the fixed terminal 3, the temperature detection units 35 corresponding to the electrode units 33-6 and the electrode units 33-7 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B in this group of ADC units 52. The temperature detection units 35 corresponding to the electrode units 33-6 and the electrode units 33-7 are connected in series. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-7 is conductively grounded, and the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-8, the electrode units 33-9, and the electrode units 33-10 are all open, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, it will not affect the resistance value of the temperature detection units 35 corresponding to the electrode units 33-6 and the electrode units 33-7. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-6 and the electrode units 33-7 operate effectively on the second detection channel B of this group of ADC units 52. The temperature detection signal (voltage value) collected by the second detection channel B is the sum of the voltage values of the temperature detection units 35 corresponding to the electrode units 33-6 and the electrode units 33-7. Subtracting the voltage value of the temperature detection unit 35 corresponding to the aforementioned electrode unit 33-6, the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-7 can be obtained, realizing the accurate temperature detection of the electrode unit 33-7.

[0109] And so on, the temperature signals at each electrode unit 33 in the second row group can be sequentially collected through the second detection channel B, the temperature signals at each electrode unit 33 in the third row group can be sequentially collected through the third detection channel C, and the temperature signals at each electrode unit 33 in the fourth row group can be sequentially collected through the fourth detection channel D.

[0110] Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can collect the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of a certain electrode plate 13 by controlling a group of two-way switching switches 55 and a group of control switches 54 that are all electrically connected to the electrode plate 13. Similarly, the temperature detection signals of the temperature sensors 34 of each electrode unit 33 of other electrode plates 13 can be obtained.

[0111] The first controller 51 or the second controller 37, multiple groups of ADC units 52, and multiple groups of bidirectional switching switches 55 can automatically perform operations through pre-programmed program codes. For example, the first controller 51 or the second controller 37 first controls a bidirectional switching switch 55 in the corresponding group of bidirectional switching switches 55 to switch to terminal 1, making terminal 1 of the bidirectional switching switch 55 conducting and terminal 2 non-conducting, so that the corresponding dual-purpose signal line 19 of the corresponding electrode plate 13 is electrically connected to the corresponding group of ADC units 52. The first switching end 1 of the rectification switching unit 16 linked to the bidirectional switching switch is connected to the fixed end. Then, the control switch 54-1 in the corresponding group of control switches 54 is closed, and the remaining control switches 54-2 to 54-5 in this group of control switches 54 are opened. During this period, the corresponding detection channel of this group of ADC units 52 acquires the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 in the corresponding row group in the corresponding electrode plate 13, converts it into a digital temperature signal, and stores it in a separately provided memory. Then, after an interval of a preset time, the first controller 51 or the second controller 37 closes the second control switch 54-2 in this group of control switches 54, and opens the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 in this group of control switches 54. During this period, the corresponding detection channel of this group of ADC units 52 acquires the temperature detection signals of two series-connected temperature detection units 35, and subtracts the previously acquired temperature detection signal to obtain the temperature detection signal corresponding to the current electrode unit 33. In this way, by sequentially and separately conducting each control switch 54 in this group of control switches 54, the temperature detection signals of all temperature detection units 35 on the electrode plate 13 can be obtained. Similarly, through this kind of operation, the temperature detection signals of all temperature detection units 35 on at least a pair of electrode plates 13 can be obtained.

[0112] It should be noted that in some other embodiments, the multiplexing switching unit is further configured to, when the control switch 54 corresponding to any one column group is closed, switch the target dual-purpose signal line 19 to be connected to the corresponding temperature sampling point, and perform linkage through the rectification switching unit 16 corresponding to the target dual-purpose signal line 19, so that the first switching end 1 of the rectification switching unit 16 corresponding to the target dual-purpose signal line 19 is connected to the fixed end 3, so that the analog temperature signals detected by the corresponding temperature detection units 35 in this column group are respectively sampled.

[0113] Specifically, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a control switch 54 in a group of control switches 54 electrically connected to a certain electrode plate 13 to be closed, and at the same time control each bidirectional switching switch 55 in the multiplexing switching unit to conduct terminal 1 in sequence, so that the detection channels A, B, C, and D in this group of ADC units 52 sample the temperature detection signals at each electrode unit 33 in the same column group in sequence.

[0114] For example, the first control switch 54-1 can be controlled to close first, while the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all opened. Then, when only the first bidirectional switch 55-1 is switched to its terminal 1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed terminal 3, the temperature detection unit 35 corresponding to the electrode unit 33-1 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the group of ADC units 52. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is conductively grounded, while the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-2, 33-3, 33-4, and 33-5 are all open, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-1 will not be affected. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-1 operates effectively on the first detection channel A of the group of ADC units 52, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1, realizing the accurate temperature detection at the electrode unit 33-1.

[0115] When only the second bidirectional switching switch 55-2 is switched to its terminal 1, the first bidirectional switching switch 55-1, the third bidirectional switching switch 55-3, and the fourth bidirectional switching switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the second row group is connected to the fixed terminal 3, the temperature detection unit 35 corresponding to the electrode unit 33-6 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B of the group of ADC units 52. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is conductively grounded, and the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-7, 33-8, 33-9, and 33-10 are all disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, it will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-6. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-6 operates effectively on the second detection channel B of the group of ADC units 52, and the temperature detection signal (voltage value) collected by the second detection channel B is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6, realizing accurate temperature detection at the electrode unit 33-6.

[0116] And so on, the temperature detection signals of each electrode unit 33 in the first column group can be sequentially collected through the detection channels A, B, C, and D in the group of ADC units 52.

[0117] Next, the second control switch 54-2 can be controlled to close first, while the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all opened. Then, when only the first two-way switching switch 55-1 is switched to its terminal 1, the second two-way switching switch 55-2, the third two-way switching switch 55-3, and the fourth two-way switching switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the first row group is connected to the fixed terminal 3, the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are connected in series and powered on, while the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the group of ADC units 52. The temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are connected in series. Since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-2 is conductively grounded, while the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-3, 33-4, and 33-5 are all opened, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, the resistance values of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are not affected. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 operate effectively on the first detection channel A of the group of ADC units 52. The temperature detection signal (voltage value) collected by the first detection channel A is the sum of the voltage values of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. Subtracting the voltage value of the temperature detection unit 35 corresponding to the aforementioned electrode unit 33-1, the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-2 can be obtained, realizing the accurate temperature detection at the electrode unit 33-2.

[0118] Similarly, when only the second bidirectional switch 55-2 is switched to its terminal 1, the first bidirectional switch 55-1, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4 are all switched to their respective terminals 2, and when the first switching terminal 1 of the rectification switching unit 16 corresponding to the second row group is connected to the fixed terminal 3, the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B of the group of ADC units 52. The temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are connected in series. Since only the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-7 is conducting to the ground, and the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-8, 33-9, and 33-10 are all disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, the resistance values of the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are not affected. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 operate effectively on the second detection channel B of the group of ADC units 52. The temperature detection signal (voltage value) collected by the second detection channel B is the sum of the voltage values of the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7. Subtracting the voltage value of the temperature detection unit 35 corresponding to the aforementioned electrode unit 33-6, the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-7 can be obtained, realizing the accurate temperature detection at the electrode unit 33-7.

[0119] By analogy, the temperature detection signals of the respective electrode units 33 in the second column group can be sequentially collected through the detection channels A, B, C, and D in the group of ADC units 52.

[0120] Similarly, the temperature detection signals of the respective electrode units 33 in the third column group, the fourth column group, and the fifth column group can all be sampled one by one based on the above method.

[0121] Therefore, in the embodiment of the present application, by the cooperation of the control switch 54, the bidirectional switch 55, and the controllable switch 162 in the rectification switching unit 16, the temperature detection at each electrode unit 33 can be realized, without interference with each other and with high detection accuracy.

[0122] Specifically, when an alternating current signal needs to be applied to each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each two-way switch 55 among the multiple two-way switches 55 of the multiplexing switching unit electrically connected to the electrode sheet 13, such that the second terminal 2 of each two-way switch 55 is turned on and the first terminal 1 is turned off. Meanwhile, the second switching terminal 2 of the corresponding rectifying switching unit 16 is connected to the fixed terminal 3, and a power supply switch 40 electrically connected to the electrode sheet 13 is controlled to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the alternating current signal generator 39 to apply an alternating current signal to each electrode unit 33 of the electrode sheet 13 through the alternating current power line 57, and the magnitude of the voltage or current of the applied alternating current signal is adjustable. That is, the multiplexing switching unit is further configured to switch the multiple target dual-purpose signal lines 19 to be connected to the alternating current power line 57 and perform linkage through the rectifying switching unit 16 corresponding to the multiple target dual-purpose signal lines 19, such that the second switching terminal 2 of the rectifying switching unit 16 corresponding to the multiple target dual-purpose signal lines 19 is connected to the fixed terminal 3, so that each electrode unit 33 in the row group corresponding to the multiple target dual-purpose signal lines 19 is simultaneously applied with the alternating current signal based on the alternating current power line 57.

[0123] It should be noted that in some other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of two-way switches 55 electrically connected to a certain electrode sheet 13 to apply an alternating current signal to some electrode units 33 of the electrode sheet 13 within the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the second terminal 2 of the first two-way switch 55-1 among the multiple two-way switches 55 of a group of two-way switches 55 electrically connected to the electrode sheet 13 to be turned on and the first terminal 1 to be turned off. The second switching terminal 2 of the associated rectifying switching unit 16 is connected to the fixed terminal 3, and a power supply switch 40 electrically connected to the electrode sheet 13 is controlled to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the alternating current signal generator 39 to apply an alternating current signal to the electrode units 33-1 to 33-5 of the first row group of the electrode sheet 13 through the alternating current power line 57, and the magnitude of the voltage or current of the applied alternating current signal is adjustable. That is, the multiplexing switching unit is configured to switch the dual-purpose signal lines 19 corresponding to each row group to be respectively connected to the alternating current power line 57, so that the electrode units 33 of each row group are simultaneously applied with the alternating current signal based on the alternating current power line 57. It should be noted that in some other embodiments, an alternating current signal can also be applied to two row groups or three row groups of electrode units 33 simultaneously within the same time period, which will not be elaborated here in detail.

[0124] It should be noted that in the embodiments of the present application, the control switches 54 respectively and electrically connected to the multiple ground wires 18 of the electrode sheet 13 and the bidirectional switching switches 55 respectively and electrically connected to the multiple dual-purpose signal lines 19 of the electrode sheet 13 are both provided in the adapter 20. However, in other embodiments, the control switches 54 electrically connected to the ground wires 18 and the bidirectional switching switches 55 electrically connected to the dual-purpose signal lines 19 can also be provided on the electrode sheet 13 or in the electric field generator 30, which will not be elaborated here. In addition, the ADC unit 52 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0125] The tumor electric field treatment system 100 of the present application can realize real-time, comprehensive and accurate monitoring of the temperatures of all the electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 and without additionally increasing the cores of the first cables 15 electrically connected to the electrode sheet 13. Furthermore, the qualification of the electrode sheet 13 can be judged according to the obtained temperature detection signals; or whether there are faults or abnormalities in the temperature detection unit 35 of the electrode sheet 13 can be judged according to the obtained temperature detection signals, and whether the electrode sheet 13 needs to be replaced can be judged based on the number of the temperature detection units 35 with faults or abnormalities; or the type of the electrode sheet can be identified according to the obtained temperature detection signals when the electrode sheet is qualified; or whether there is an over-temperature situation in the electrode units 33 of the electrode sheet 13 can be judged according to the obtained temperature detection signals when the electrode sheet is qualified, and then the alternating current signals applied to the electrode sheet 13 or the corresponding row of electrode units 33 of the electrode sheet 13 can be controlled to avoid low-temperature burns on the patient's body surface during tumor treatment through the electrode sheet 13. In addition, through the dual-purpose signal lines 19 arranged on the substrate 31 of the electrode sheet 13 of the present application, the alternating current signals can be transmitted and the direct current signals for temperature signal acquisition can also be transmitted. The two functions are completely signal-isolated through the multiplexing switching unit and the rectifying switching unit 16, which not only greatly reduces the number of conductive traces (ground wires 18, dual-purpose signal lines 19) arranged thereon, reduces the wiring difficulty of the substrate 31, simplifies the manufacturing process, but also reduces the weight of the substrate 31 and the manufacturing cost. The electrode sheet 13 of the present application can also realize effective switching between applying alternating current signals for tumor treatment and transmitting direct current signals for temperature acquisition and transmitting the obtained temperature detection signals through the combined control of the control switch 54 electrically connected to the ground wires 18 arranged thereon, the bidirectional switching switch 55 electrically connected to the dual-purpose signal lines 19 and the rectifying switching unit 16.

[0126] Specifically, when it is necessary to apply an alternating electric signal to the patient through each electrode unit 33 of a certain electrode patch 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls to disconnect all the control switches 54 in a group of control switches 54 corresponding to the electrode patch 13, and at the same time controls to switch all the bidirectional switches 55 in a group of bidirectional switches 55 corresponding to the electrode patch 13 to their respective 2 ends, so that the 1 ends of these bidirectional switches 55 are all disconnected and the 2 ends are all conducted, realizing that each two-way signal line 19 of the electrode patch 13 is electrically connected to an alternating power supply line 57 corresponding to the adapter 20 and the electrode patch 13, and based on the linkage of each rectifying and switching unit 16, the alternating electric signal is transmitted to each electrode unit 33 of the electrode patch 13. When the digital temperature signal converted from the temperature detection signal of the temperature detection unit 35 corresponding to all the electrode units 33 of the detected electrode patch 13 is much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 to continue generating an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude through its second controller 37, and then transmits it to the corresponding electrode patch 13 through a corresponding alternating power supply line 57 of the adapter 20, so as to continue applying the alternating electric signal to the pair of electrode patches 13; when the digital temperature signal converted from the temperature detection signal of the temperature detection unit 35 corresponding to all the electrode units 33 of the detected electrode patch 13 is lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating electric signal generated by the AC signal generator 39 through the second controller 37, and then reduce the voltage or current of the alternating electric signal applied to the pair of electrode patches 13; when it is detected that the digital temperature signal converted from the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode patch 13 is greater than the preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode patch 13 to be disconnected to stop applying the alternating electric signal to the electrode patch 13; or the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls all the bidirectional switches 55 in a group of bidirectional switches 55 electrically connected to the electrode patch 13 to switch from their 2 ends to their 1 ends, that is, controls the 1 ends of all the bidirectional switches 55 in a group of bidirectional switches 55 electrically connected to the electrode patch 13 to be all conducted and the 2 ends to be all disconnected, thereby realizing stopping applying the alternating electric signal to the electrode patch 13;Alternatively, when it is detected that the digital temperature signal obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 in a certain electrode patch 13 is greater than the preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode patch 13 to continue conducting, and the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls a bidirectional switching switch 55 electrically connected to the electrode unit 33 of the electrode patch 13 to switch from its terminal 2 to its terminal 1. Meanwhile, the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls the remaining bidirectional switching switches 55 electrically connected to the electrode units 33 in different rows from the electrode unit 33 whose digital temperature signal obtained by converting the temperature detection signal of the electrode patch 13 does not exceed the preset temperature threshold and whose digital temperature signal obtained by converting the temperature detection signal exceeds the preset temperature threshold to continue to be electrically connected to their respective terminals 2, so as to stop applying the alternating electric signal to all the electrode units 33 in the row where the electrode unit 33 whose digital temperature signal obtained by converting the temperature detection signal of the electrode patch 13 exceeds the preset temperature threshold is located, and continue to apply the alternating electric signal to the remaining row electrode units 33 whose digital temperature signals obtained by converting the temperature detection signals of the electrode patch 13 do not exceed the preset temperature threshold. Thus, a control method for applying an alternating electric signal based on a temperature detection signal of the tumor electric field treatment system 100 is realized, and the tumor electric field treatment system 100 is controlled to operate reliably and efficiently, improving the treatment effect.

[0127] An embodiment of the present application provides an electrode patch temperature detection method, which is applied to the above-mentioned electrode patch 13 or tumor electric field treatment system 100. Refer to Figure 8 as shown, and it includes the following steps:

[0128] Step 210: Control the multiplexing switching unit to connect any row group corresponding dual-purpose signal line 19 in the corresponding electrode patch 13 to the corresponding temperature sampling point, where the first switching end 1 of the rectifying switching unit 16 corresponding to the row group in the corresponding electrode patch 13 is connected to the fixed end 3.

[0129] Specifically, control the power supply switch 40, the bidirectional switching switches 55 electrically connected to the respective electrode units 33 of the electrode patch 13, and the rectifying switching unit 16 to disconnect the alternating electric signal applied to the respective electrode units 33 of the electrode patch 13 and simultaneously connect the direct current signal to the signal end 35-2 of the temperature detection unit 35 applied to the respective electrode units 33 of the electrode patch 13.

[0130] Further, control the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 to switch from the end thereof electrically connected to the alternating current signal to the end thereof electrically connected to the direct current signal, that is, control the bidirectional switching switch 55 electrically connected to the electrode sheet 13 to switch from its terminal 2 to its terminal 1, and at the same time, the rectifying switching unit 16 switches from the second switching terminal 2 to the first switching terminal 1 and is connected to the fixed terminal 3; or, control the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 to switch each electrode unit 33 of the electrode sheet 13 from the conducting state to the off state, and at the same time, switch the signal terminal 35-2 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 from the off state to the conducting state.

[0131] Step 220: Control the control switch 54 corresponding to each column group to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

[0132] Specifically, sequentially turn on the control switch 54 electrically connected to the ground terminal 35-1 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 to obtain the temperature detection signal of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13.

[0133] In some embodiments, controlling the control switch 54 corresponding to each of the column groups includes:

[0134] Control the control switch 54 corresponding to each of the column groups to be sequentially closed, so as to sequentially sample the analog temperature signals detected by each temperature detection unit 35 in the row group based on the corresponding temperature sampling point.

[0135] In other embodiments, when the control switch 54 corresponding to any one of the column groups is closed, the method further includes:

[0136] Control the multiplexing switching unit to sequentially connect each dual-purpose signal line 19 corresponding to each row group in the corresponding electrode sheet 13 to the corresponding temperature sampling point, so as to separately sample the analog temperature signals detected by each temperature detection unit 35 in the column group based on the corresponding temperature sampling point.

[0137] By using the electrode sheet 13 temperature detection method of the present application, the temperatures of all electrode units 35 of the electrode sheet 13 can be obtained quickly and accurately; and based on the temperature detection signals of all temperature detection units 35 of the obtained electrode sheet 13, it can be judged whether there is a fault in the temperature detection unit 35 of the electrode sheet, whether there is an abnormality, or whether the electrode sheet 13 is qualified and needs to be replaced; also, when each temperature detection unit 35 of the electrode sheet 13 is normal, based on the temperature detection signals of all temperature detection units 35 of the obtained electrode sheet 13, it can be judged whether there is overheating in each electrode unit 33 of the electrode sheet 13 and then control the alternating current signal applied to the electrode sheet 13 or each electrode unit 33 of the electrode sheet 13 to improve the treatment effect; also, when the temperature detection signals of each temperature detection unit 35 of the electrode sheet 13 are normal, the electrode sheet type can be identified.

[0138] In the adapter 20 of the tumor electric field treatment system 100 according to the embodiment of the present application, a preset threshold, a first preset temperature, a second preset temperature, and a preset temperature threshold are provided in the first controller 51 or the electric field generator 30, where the first preset temperature is lower than the second preset temperature, and the second preset temperature is lower than the preset temperature threshold.

[0139] Refer to Figure 9 As shown, the present application also provides an electrode sheet temperature abnormality detection method, which includes the following steps:

[0140] Step 210: Control the multiplexing switching unit to connect any one row group corresponding dual-purpose signal line 19 in the corresponding electrode sheet 13 to the corresponding temperature sampling point, where the first switching end 1 of the rectifying switching unit 16 corresponding to this row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0141] Step 220: Control the control switch 54 corresponding to each column group to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13.

[0142] Step 230: Judge whether the electrode sheet 13 is abnormal according to the temperature detection signal.

[0143] In some embodiments, in step 230, judging whether the electrode sheet 13 is abnormal according to the temperature detection signal specifically includes the following steps:

[0144] Step 231: Compare the temperature at each electrode unit 33 in the corresponding electrode sheet 13 with the preset temperature threshold according to the temperature detection signal. Specifically, the digital temperature signal corresponding to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the obtained electrode sheet 13 can be compared with the preset temperature threshold.

[0145] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal according to the comparison result. Specifically, determine whether there is any abnormal temperature in each electrode unit 33 of the electrode sheet 13 according to the comparison result.

[0146] The comparison results in step 232 include not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Not exceeding the preset temperature threshold includes being far lower than the preset temperature threshold and being close to the preset temperature threshold. The preset temperature threshold is 40°C - 42°C. Optionally, the preset temperature threshold is 40.5°C - 41.5°C. Optionally, the preset temperature threshold is 41°C - 41.5°C. Optionally, the preset temperature threshold is 41°C.

[0147] The process of determining whether the temperature of the electrode sheet 13 is abnormal according to the comparison result in step 232 is specifically as follows: When the temperature at any one of the electrode units 33 in the corresponding electrode sheet 13 exceeds the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. And when the temperatures at all the electrode units 33 in the corresponding electrode sheet 13 do not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0148] In some other embodiments, the process of determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0149] Step 233: When it is determined according to the temperature detection signal that any one of the electrode units 33 in the corresponding electrode sheet 13 is abnormal or fails, determine that the electrode sheet 13 is unqualified.

[0150] Specifically, determine whether the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 are abnormal or fail according to the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the obtained electrode sheet 13; then determine whether the electrode sheet 13 is qualified according to whether the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 are abnormal or fail. Among them, when the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 are abnormal or fail, it is determined that the electrode sheet 13 is unqualified; when the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 are not abnormal or do not fail, it is determined that the electrode sheet 13 is qualified.

[0151] In still some other embodiments, the process of determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0152] Step 234: When it is determined according to the temperature detection signal that there are abnormal or failed electrode units 33 in the corresponding electrode sheet 13, determine the number of the abnormal or failed electrode units 33.

[0153] Step 235: When the number of electrode units 33 with anomalies or malfunctions reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0154] Specifically, based on the temperature detection signals of the temperature detection units 35 corresponding to the respective electrode units 33 in the obtained electrode sheet 13, it is determined whether there are anomalies or malfunctions in the temperature detection units 35 corresponding to the respective electrode units 33 in the electrode sheet 13; then, based on whether there are anomalies or malfunctions in the temperature detection units 35 corresponding to the respective electrode units 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0155] For example, when there are anomalies or malfunctions in the temperature detection units 35 corresponding to the respective electrode units 33 in the electrode sheet 13 and the number of temperature detection units 35 with anomalies or malfunctions exceeds the preset threshold, it is determined that the electrode sheet 13 needs to be replaced; when the number of temperature detection units 35 with anomalies or malfunctions in the electrode sheet 13 does not exceed the preset threshold, it is determined that the electrode sheet 13 does not need to be replaced. Among them, the preset threshold is 20% of the total number of all temperature detection units 35 of the electrode sheet 13.

[0156] Refer to Figure 10 As shown, the present application also provides a control method for a tumor electric field treatment system, which includes the following steps:

[0157] Step 210: Control the multiplexing switching unit so that any one row group corresponding dual-purpose signal line 19 in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point, where the first switching end 1 of the rectifying switching unit 16 corresponding to this row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0158] Step 220: Control the control switch 54 corresponding to each column group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13.

[0159] Step 240: Control the intensity of the alternating electric signal applied to the electrode unit 33 according to the temperature detection signal.

[0160] Specifically, when it is determined that the electrode sheet 13 does not need to be replaced, control or adjust the alternating electric signal applied to each electrode unit 33 in the electrode sheet 13 according to the temperature detection signals detected by the temperature detection units 35 corresponding to the respective electrode units 33 in the obtained electrode sheet 13. That is to say, steps 234 - 235 can be added between step 240 and step 220.

[0161] In some embodiments, the control of the alternating current signal intensity applied to the electrode unit 33 according to the temperature detection signal in step 240 specifically includes the following steps:

[0162] Step 241: Compare the temperature at each electrode unit 33 in the electrode sheet 13 with a preset temperature threshold according to the temperature detection signal.

[0163] Step 242: Control the alternating current signal intensity according to the comparison result.

[0164] In some embodiments, the control of the alternating current signal intensity according to the comparison result in step 242 specifically includes:

[0165] Step 2421: When the temperature at at least one electrode unit 33 exceeds the preset temperature threshold, stop applying the alternating current signal to the electrode unit 33 of the electrode sheet 13. Specifically, when there is a temperature exceeding the preset temperature threshold among the temperature detection signals of all electrode units 33 of the obtained electrode sheet 13, stop applying the alternating current signal to the electrode unit 33 of the electrode sheet 13. And when the temperature detection signals of each electrode unit 33 in the obtained electrode sheet 13 do not exceed the preset temperature threshold, continue to apply the alternating current signal to each electrode unit 33 of the electrode sheet 13.

[0166] In some embodiments, stopping applying the alternating current signal to the electrode unit 33 of the electrode sheet 13 in step 2421 specifically includes: stopping applying the alternating current signal to all electrode units 33 of the electrode sheet 13; or stopping applying the alternating current signal to all electrode units 33 in the row group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located.

[0167] Further, in the case of stopping applying the alternating current signal to all electrode units 33 in the row group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located, continue to apply the alternating current signal to the electrode units 33 in other row groups of the electrode sheet 13. Among them, the intensity of the alternating current signal applied to the electrode units 33 in other row groups of the electrode sheet 13 is adjustable. For example, all electrode units 33 whose corresponding temperature in the temperature detection signal of the electrode sheet 13 does not exceed the preset temperature threshold and are in different rows from the electrode units 33 whose temperature detection signal exceeds the preset temperature threshold will continue to be applied with the alternating current signal, and this signal is adjustable.

[0168] In some other embodiments, the control of the alternating current signal intensity according to the comparison result in step 242 specifically includes:

[0169] Step 2422: When the temperatures at all the electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperatures at all the electrode units 33 in the electrode sheet 13 do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, where the first preset temperature is less than the preset temperature threshold.

[0170] In step 2422, the increase amplitude of the electric field intensity corresponding to each row group where the intensity of the alternating electric signal is increased is the same.

[0171] Step 2423: When the temperatures at all the electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if there is at least one electrode unit 33 in the electrode sheet 13 where the temperature exceeds the first preset temperature and is less than the preset temperature threshold, keep the intensity of the alternating electric signal currently applied to the electrode units 33 of the electrode sheet 13 unchanged.

[0172] Step 2424: When the temperatures at all the electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if there is at least one electrode unit 33 in the electrode sheet 13 where the temperature exceeds the second preset temperature and is less than the preset temperature threshold, decrease the intensity of the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, where the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0173] In step 2424, the decrease amplitude of the electric field intensity corresponding to each row group where the intensity of the alternating electric signal is decreased is the same.

[0174] Exemplarily, when the temperature corresponding to the temperature detection signal is much lower than the preset temperature threshold, continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 by increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 by keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature corresponding to the temperature detection signal is close to the preset temperature threshold, continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 by keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 by reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0175] In some other embodiments, the control of the intensity of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0176] Step 2425: Determine the number of over-temperature row groups when the temperature at at least one electrode unit 33 exceeds a preset temperature threshold.

[0177] Step 2426: Stop applying an alternating electric signal to all electrode units 33 of the electrode sheet 13 when the number of over-temperature row groups exceeds a preset number threshold.

[0178] Step 2427: Stop applying an alternating electric signal to all electrode units 33 of the row group where the electrode units 33 exceeding the preset temperature threshold in the electrode sheet 13 are located when the number of over-temperature row groups does not exceed the preset number threshold.

[0179] Further, when stopping applying an alternating electric signal to all electrode units 33 of the row group where the electrode units 33 exceeding the preset temperature threshold in the electrode sheet 13 are located, continue to apply an alternating electric signal to the electrode units 33 of other row groups in the electrode sheet 13. Among them, the intensity of the alternating electric signal applied to the electrode units 33 of other row groups in the electrode sheet 13 is adjustable.

[0180] Step 2428: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature at each electrode unit 33 in the non-over-temperature row groups does not exceed a first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33 in the non-over-temperature row groups, where the first preset temperature is less than the preset temperature threshold.

[0181] In step 2428, the increase amplitude of the electric field intensity corresponding to each row group where the intensity of the alternating electric signal is increased is the same.

[0182] Step 2429: When the number of over-temperature row groups does not exceed the preset number threshold, if there is at least one electrode unit 33 in the non-over-temperature row groups where the temperature exceeds the first preset temperature and is less than the preset temperature threshold, keep the intensity of the alternating electric signal currently applied to the electrode units 33 in the non-over-temperature row groups unchanged.

[0183] Step 2430: When the number of over-temperature row groups does not exceed the preset number threshold, if there is at least one electrode unit 33 in the non-over-temperature row groups where the temperature exceeds a second preset temperature and is less than the preset temperature threshold, decrease the intensity of the alternating electric signal applied to the electrode units 33 in the non-over-temperature row groups, where the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0184] In step 2430, the decrease amplitude of the electric field intensity corresponding to each row group where the intensity of the alternating electric signal is decreased is the same.

[0185] Exemplarily, when the temperature corresponding to the temperature detection signal is much lower than the preset temperature threshold, the alternating current signal is continuously applied to each electrode unit 33 of the electrode sheet 13 by increasing the voltage or current amplitude of the alternating current signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating current signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature corresponding to the temperature detection signal is close to the preset temperature threshold, the alternating current signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating current signal is continuously applied to each electrode unit 33 of the electrode sheet 13 by reducing the voltage or current amplitude of the alternating current signal applied to each electrode unit 33 of the electrode sheet 13.

[0186] Referring to Figure 11 as shown, the present application also provides a method for identifying the type of electrode sheet, which includes the following steps:

[0187] Step 210: Control the multiplexing switching unit to connect any one row group corresponding dual-purpose signal line 19 in the corresponding electrode sheet 13 to the corresponding temperature sampling point, wherein the first switching end 1 of the rectifying switching unit 16 corresponding to this row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0188] Step 220: Control each control switch 54 corresponding to each column group to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point, so as to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13.

[0189] Step 250: Identify the type of the electrode sheet 13 according to the temperature detection signal.

[0190] Specifically, when the electrode sheet 13 is qualified or there is no abnormality or failure in each temperature detection unit 35 of the electrode sheet 13, the type of the electrode sheet 13 is identified according to the temperature detection signal detected by each temperature detection unit 35 of each electrode unit 33 in the obtained electrode sheet 13.

[0191] The present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned tumor electric field therapy system 100 or for the above-mentioned electrode sheet 13. The method includes: combining control of the control switch 54 and the bidirectional switching switch 55 electrically connected to the electrode sheet 13 to enable each electrode unit 33 of the electrode sheet 13 to switch between applying an alternating current signal and collecting a temperature detection signal.

[0192] Referring to Figure 12As shown in the figure, the present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 13. The method includes:

[0193] Step 310: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 and execute step 320;

[0194] Step 320: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to collect the temperature detection signals of each electrode unit 33 of the electrode sheet 13 row by row or column by column and execute step 330;

[0195] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 according to the collected temperature detection signals and execute step 340;

[0196] Step 340: Control the working states of each electrode unit 33 of the electrode sheet 13 according to the determined combined control mode of the control switch 54 and the bidirectional switch 55.

[0197] The working states of each electrode unit 33 of the electrode sheet 13 in step 340 include at least one of: stopping applying the alternating electric signal and continuing to collect the temperature detection signals, and stopping collecting the temperature detection signals and continuing to apply the alternating electric signal. Continuing to apply the alternating electric signal includes continuing to apply the alternating electric signal in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal, or continuing to apply the alternating electric signal in a manner of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged, or continuing to apply the alternating electric signal in a manner of decreasing the voltage or current amplitude of the currently applied alternating electric signal.

[0198] The working states of each electrode unit 33 of the electrode sheet 13 are determined by the temperature detection signals collected by it. Each electrode unit 33 of the electrode sheet 13 is divided into different regions, and each electrode unit 33 in each region can be cycled between applying the alternating electric signal and collecting the temperature detection signals through the combined control of the control switch 54 and the bidirectional switch 55.

[0199] The embodiment of the present application provides another electrode sheet temperature detection method for the tumor electric field therapy system 100. Please refer to Figure 13 As shown in the figure, the temperature detection method includes:

[0200] Step 510: Disconnect the input of the alternating electric signal of the electrode sheet 13, combine and control a plurality of control switches 54 and a plurality of bidirectional switches 55, and obtain the temperature detection signals of the temperature sensors 34 of the electrode sheet 13 corresponding to each combination in all combinations;

[0201] Step 520: Sample and convert the temperature detection signals detected by each temperature sensor 34 in the electrode sheet 13 to obtain digital temperature signals;

[0202] Step 530: Transmit the digital temperature signals to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 33 according to the digital temperature signals.

[0203] In step 510, the combined control of the multiple control switches 54 and the multiple bidirectional switching switches 55 specifically includes:

[0204] Step 511: Control the multiple bidirectional switching switches 55 so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are sequentially connected to the corresponding temperature sampling points; Place one bidirectional switching switch 55 at end 1, and the remaining bidirectional switching switches 55 are all placed at end 2 to conduct the electrical connection between the signal terminals 35-2 of the temperature detection units 35 corresponding to the electrode units 33 in the row group corresponding to the bidirectional switching switch 55 placed at end 1 and the corresponding ADC unit 52;

[0205] Step 512: Sequentially and separately close one of the multiple control switches 54 to individually collect the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the corresponding row group.

[0206] Sequentially and separately closing one of the multiple control switches 54 in step 512 can make the ADC unit 52 grounded in sequence with the temperature detection units 35 in the column group corresponding to the closed control switch 54.

[0207] Thus, the temperature detection signals of the corresponding temperature detection units 35 in each row group can be obtained in sequence. Furthermore, after being processed by the adapter 20 or the electric field generator 30, the temperatures corresponding to all the electrode units 33 on the electrode sheet 13 can be obtained, so that the temperature detection on the patient's body surface is more comprehensive and accurate.

[0208] For the tumor electric field therapy system 100 according to the embodiments of the present application, temperature detection can be performed on a single electrode unit 33. For example, temperature detection can be performed on a single electrode unit 33 located in the first column group. Taking the electrode unit 33-1 as an example: disconnect the input of the alternating electric signal, place the bidirectional switching switch 55 corresponding to the row group where the electrode unit 33-1 to be individually temperature-measured is located at the 1 end, and place the remaining bidirectional switching switches 55 at the 2 end; at the same time, turn on and ground the control switch 54 corresponding to the column group where the electrode unit 33-1 to be individually temperature-measured is located, and disconnect all the remaining control switches 54. Thus, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1 to be individually temperature-measured can be sampled to obtain the temperature of the electrode unit 33-1. For example, place the first bidirectional switching switch 55-1 corresponding to the electrode unit 33-1 at the 1 end, and place all the remaining bidirectional switching switches (55-2 to 55-4) at the 2 end; at the same time, close and ground the first control switch 54-1 corresponding to the electrode unit 33-1, and disconnect all the remaining control switches (54-2 to 54-5). Thus, the temperature of the electrode unit 33-1 can be detected. Similarly, the other electrode units 33-6, 33-11, and 33-16 in the first column group can also be individually temperature-detected. In addition to performing temperature detection on a single electrode unit 33 in the first column group, the temperature detection signals of other electrode units 33 are combined signals. For example, when the first bidirectional switching switch 55-1 corresponding to the electrode unit 33-2 is placed at the 1 end, and all the remaining bidirectional switching switches (55-2 to 55-4) are placed at the 2 end; at the same time, the second control switch 54-2 corresponding to the electrode unit 33-2 is closed and grounded, and all the remaining control switches (54-1, 54-3 to 54-5) are disconnected. At this time, the obtained temperature detection signal is the combined temperature detection signal of the electrode unit 33-1 and the electrode unit 33-2. Subtracting the temperature detection signal of the aforementioned electrode unit 33-1 from the combined temperature detection signal is the temperature detection signal of the electrode unit 33-2.

[0209] The embodiments of the present application also provide another method for applying an alternating electric signal for tumor electric field therapy, which is applied to the above-mentioned tumor electric field therapy system 100. Please refer to Figure 14 As shown, the method for applying the alternating electric signal includes:

[0210] Step 610: Determine the area (1-4) where the electrode unit 33 that needs to apply the alternating electric signal is located in the electrode sheet 13;

[0211] Step 611: Combine and control a plurality of control switches 54 and a plurality of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to apply the alternating electric signal.

[0212] In step 611, the combination of the multiple control switches 54 and the multiple bidirectional switching switches 55 electrically connected to the electrode sheet 13 is specifically as follows:

[0213] Step 612: Disconnect all the control switches 54 electrically connected to the electrode sheet 13;

[0214] Step 613: Determine the row groups where the electrode units 33 in the regions where alternating current signals need to be applied are located according to the regions where the electrode units 33 of the electrode unit 33 are located;

[0215] Step 614: Determine the bidirectional switching switches 55 electrically connected to the electrode units 33 in these row groups according to the row groups where the electrode units 33 that need to apply alternating current signals are located;

[0216] Step 615: Control the bidirectional switching switches 55 electrically connected to the electrode units 33 that need to apply alternating current signals to electrically connect the electrode units 33 that need to apply alternating current signals to the alternating current power supply line 57 to apply an alternating current signal; at the same time, control the remaining bidirectional switching switches 55 to disconnect the electrical connection between the electrode units 33 in the regions where no alternating current signal needs to be applied and the alternating current power supply line 57 to stop applying the alternating current signal.

[0217] In step 615, "electrically connect the electrode units that need to apply alternating current signals to the alternating current power supply line 57 to apply an alternating current signal and disconnect the electrical connection between the electrode units 33 in the regions where no alternating current signal needs to be applied and the alternating current power supply line 57 to stop applying the alternating current signal" is achieved by placing the bidirectional switching switches 55 electrically connected to the electrode units 33 in the row groups corresponding to the regions (1-4) where the alternating current signal needs to be applied in the electrode sheet 13 at their 2 ends, and placing all the bidirectional switching switches 55 electrically connected to the electrode units 33 in the remaining row groups at their 1 ends.

[0218] In the adapter 20 of the tumor electric field treatment system 100 according to the embodiment of the present application, the first controller 51 or the electric field generator 30 is provided with a preset number threshold, a first preset temperature t1, a second preset temperature t2, and a preset temperature threshold t0, where the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0219] The embodiment of the present application also provides an alternating current signal application method based on a temperature detection signal for the above-mentioned tumor electric field treatment system 100. Please refer to Figure 15 As shown, the application method includes:

[0220] Step 710: Start the tumor electric field treatment system 100;

[0221] Step 711: Combine to control the control switch 54 (also known as the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switching switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0222] Step 712: Combine to control the control switch 54 electrically connected to the electrode sheet 13 and the bidirectional switching switch 55 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0223] Step 713: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. When there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute Step 714. When there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute Step 715;

[0224] Step 714: Continue to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to Step 712;

[0225] Step 715: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2. When there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute Step 716. When there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute Step 717;

[0226] Step 716: Continue to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to Step 712;

[0227] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. When there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute Step 718. When there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute Step 719;

[0228] Step 718: Continue to apply an alternating electrical signal to all electrode units 33 of the electrode sheet 13 in a manner of decreasing the voltage or current amplitude of the currently applied alternating electrical signal and return to Step 712;

[0229] Step 719: Determine the number of over-temperature regions and execute Step 720, where the over-temperature region is the region containing the electrode unit whose temperature exceeds the preset temperature threshold t0, and the non-over-temperature region is the region where the temperatures of all its electrode units do not exceed the preset temperature threshold t0;

[0230] Step 720: Determine whether the number of over-temperature regions exceeds the preset number threshold. When the number of over-temperature regions exceeds the preset number threshold, execute Step 721. When the number of over-temperature regions does not exceed the preset number threshold, execute Step 724;

[0231] Step 721: Stop applying an alternating electric signal to each electrode unit 33 of the electrode sheet 13 and execute Step 722;

[0232] Step 722: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute Step 723;

[0233] Step 723: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. When there is no electrode unit 33 on the electrode sheet 13 whose temperature exceeds the first preset temperature t1, return to Step 711. When there is an electrode unit 33 on the electrode sheet 13 whose temperature exceeds the first preset temperature t1, return to Step 722;

[0234] Step 724: Distinguish the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. When the area is the over-temperature area, execute Step 725. When the area is the non-over-temperature area, execute Step 726;

[0235] Step 725: Stop applying an alternating electric signal to each electrode unit 33 in the over-temperature area and execute Step 731;

[0236] Step 726: Determine whether the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the first preset temperature t1, execute Step 727. When there is a temperature that exceeds the first preset temperature t1 among the temperatures of each electrode unit 33 in the non-over-temperature area, execute Step 728;

[0237] Step 727: Continue to apply an alternating electric signal to each electrode unit 33 in the non-over-temperature area of the electrode sheet 13 in a way of increasing the voltage or current amplitude of the currently applied alternating electric signal and execute Step 731;

[0238] Step 728: Determine whether the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the second preset temperature t2, execute Step 729. When there is a temperature that exceeds the second preset temperature t2 among the temperatures of each electrode unit 33 in the non-over-temperature area, execute Step 730;

[0239] Step 729: Continue to apply an alternating electric signal to each electrode unit 33 in the non-over-temperature area of the electrode sheet 13 in a way of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged and execute Step 731;

[0240] Step 730: Continue to apply an alternating current signal to each electrode unit 33 in the non-overheating area of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating current signal, and execute Step 731;

[0241] Step 731: Combine the control of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-obtain the temperatures of the respective electrode units 33 of the electrode sheet 13, and select to execute Step 732 or Step 734. The temperatures of the respective electrode units 33 of the electrode sheet 13 include the temperatures of the respective electrode units 33 in the overheating area and the temperatures of the respective electrode units 33 in the non-overheating area;

[0242] Step 732: Determine whether the temperatures of the respective electrode units 33 in the overheating area do not exceed the first preset temperature t1. When the temperatures of the respective electrode units 33 in the overheating area do not exceed the first preset temperature t1, execute Step 733. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the respective electrode units 33 in the overheating area, return to Step 731;

[0243] Step 733: Re-determine this area as a non-overheating area and execute Step 734;

[0244] Step 734: Determine whether the temperatures of the respective electrode units 33 in the obtained non-overheating area do not exceed the first preset temperature t1. When the temperatures of the respective electrode units 33 in the non-overheating area do not exceed the first preset temperature t1, execute Step 735. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the respective electrode units 33 in the non-overheating area, execute Step 736;

[0245] Step 735: Continue to apply an alternating current signal to each electrode unit 33 in the non-overheating area in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal, and return to Step 712;

[0246] Step 736: Determine whether the temperatures of the respective electrode units 33 in the obtained non-overheating area do not exceed the second preset temperature t2. When the temperatures of the respective electrode units 33 in the non-overheating area do not exceed the second preset temperature t2, execute Step 737. When there is a temperature exceeding the second preset temperature t2 among the temperatures of the respective electrode units 33 in the non-overheating area, execute Step 738;

[0247] Step 737: Continue to apply an alternating current signal to each electrode unit 33 in the non-overheating area in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged, and return to Step 712;

[0248] Step 738: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 739. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 719.

[0249] Step 739 : Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712 .

[0250] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 711 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0251] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that applies an alternating electrical signal to each electrode unit 33; or

[0252] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0253] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective two ends.

[0254] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in step 712, step 722, and step 731 is specifically as follows:

[0255] Control the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, control each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from the end at which the alternating electric signal is applied to each electrode unit 33 to the end at which the temperature of each electrode unit 33 is collected in sequence in a time-sharing manner, and the remaining two-way switching switches 55 are all switched from the end at which the temperature of each electrode unit 33 is collected to the end at which the alternating electric signal is applied to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0256] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from its two ends, which apply the alternating electric signal to each electrode unit 33, to its one end in a time-sharing manner, and controlling the remaining two-way switching switches 55 to switch from its one end to its two ends, which apply the alternating electric signal to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0257] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52 in a time-division order, and the remaining two-way switching switches 55 to be switched from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57, and at the same time each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-division order to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0258] The power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and each of the two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal in a time-sharing manner, and the remaining two-way switching switches 55 switch from transmitting a direct current signal or a temperature detection signal to transmitting an alternating electric signal. At the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0259] The first preset temperature in Step 713, Step 723, Step 726, Step 732, and Step 734 is 40°C - 40.3°C, preferably 40.2°C. The second preset temperature in Step 715, Step 728, and Step 736 is 40.4°C to 40.6°C, preferably 40.5°C; the preset temperature threshold in Step 717 and Step 738 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in Step 720 is preferably 2.

[0260] The process of continuously applying an alternating electric signal in Step 714, Step 716, Step 718, Step 727, Step 729, Step 730, Step 735, Step 737, and Step 739 is specifically as follows:

[0261] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal to conduct the alternating electric signal transmission path electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal, so as to continue to apply an alternating electric signal to the electrode unit 33 that needs to continuously apply an alternating electric signal; or

[0262] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal to switch from its respective 1 end to its respective 2 end, so as to continue to apply an alternating electric signal to the electrode unit 33 that needs to continuously apply an alternating electric signal; or

[0263] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal to electrically connect its respective 2 ends to the alternating power supply line 57, so as to continue to apply an alternating electric signal to the electrode unit 33 that needs to continuously apply an alternating electric signal; or

[0264] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal to close its respective 2 ends and disconnect its respective 1 ends, so as to continue to apply an alternating electric signal to the electrode unit 33 that needs to continuously apply an alternating electric signal; or

[0265] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continuously apply an alternating electric signal to switch the electrode unit 33 that needs to continuously apply an alternating electric signal from transmitting a temperature detection signal to applying an alternating electric signal.

[0266] In steps 714, 727, and 735, the process of increasing the voltage or current amplitude of the currently applied alternating electrical signal specifically involves boosting the voltage of the currently applied alternating electrical signal in a manner of increasing the DC voltage amplitude by 0.03 V per second.

[0267] In steps 718, 730, and 739, the process of continuing to apply the alternating electrical signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electrical signal specifically involves continuing to apply the alternating electrical signal in a manner where the voltage amplitude is 5 V less than the currently applied alternating electrical signal and lasts for 3 minutes.

[0268] The process of stopping the application of the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in step 721 specifically includes:

[0269] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power supply line 57; or

[0270] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all from the end where it applies the alternating electrical signal to each electrode unit 33 to the end where it performs temperature acquisition for each electrode unit 33; or

[0271] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all from the 2 ends where it applies the alternating electrical signal to each electrode unit 33 to its 1 end; or

[0272] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from the electrical connection between each electrode unit 33 and the alternating power supply line 57 to the electrical connection between each electrode unit 33 and the corresponding ADC unit 52; or

[0273] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to cause each electrode unit 33 of the electrode sheet 13 to switch from transmitting the alternating electrical signal to transmitting the direct current electrical signal or the temperature detection signal.

[0274] The process of stopping the application of the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 725 specifically includes:

[0275] Controlling the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the alternating power supply line 57; or

[0276] Controlling the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all from the end where it applies the alternating electrical signal to each electrode unit 33 in the over-temperature area to the end where it performs temperature acquisition for each electrode unit 33 in the over-temperature area; or

[0277] Control the bidirectional switching switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all the 2 ends that apply the alternating electric signal to each electrode unit 33 in the over-temperature area to its 1 end; or

[0278] Control the bidirectional switching switch 55 electrically connected to each electrode unit 33 in the over-temperature area to cause each electrode unit 33 in the over-temperature area to switch from being electrically connected to the alternating power supply line 57 to being electrically connected to the corresponding ADC unit 52; or

[0279] Control the bidirectional switching switch 55 electrically connected to each electrode unit 33 in the over-temperature area to cause each electrode unit 33 in the over-temperature area to switch from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal.

[0280] In the above control method, the tumor electric field treatment system 100 includes at least two pairs of electrode plates 13 to alternately apply alternating electric fields in different directions, and each electrode plate 13 can alternately switch between applying an alternating electric signal and transmitting a temperature detection signal.

[0281] In the adapter 20 of the tumor electric field treatment system 100 according to the embodiment of the present application, or in the electric field generator 30, there is also a third preset temperature t3, and the third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The embodiment of the present application also provides an alternating electric signal control method based on the temperature detection signal for the above-mentioned tumor electric field treatment system. Refer Figure 16 As shown, the alternating electric signal control method includes:

[0282] Step 810: Start the tumor electric field treatment system 100;

[0283] Step 811: Combine and control the control switch 54 (also called the grounding switch) and the bidirectional switching switch 55 electrically connected to the corresponding electrode plate 13 to apply an alternating electric signal to each electrode unit 33 of the electrode plate 13;

[0284] Step 812: Combine and control the control switch 54 and the bidirectional switching switch 55 electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13;

[0285] Step 813: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. When there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 814. When there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 815;

[0286] Step 814: Continue to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal, and return to Step 812;

[0287] Step 815: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute Step 816; when there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute Step 817;

[0288] Step 816: Continue to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged, and return to Step 812;

[0289] Step 817: Determine whether there is an electrode unit 33 whose temperature exceeds the third preset temperature t3. When there is no electrode unit 33 whose temperature exceeds the third preset temperature t3, execute Step 818; when there is an electrode unit whose temperature exceeds the third preset temperature t3, execute Step 819;

[0290] Step 818: Continue to apply an alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of decreasing the voltage or current amplitude of the currently applied alternating electric signal, and return to Step 812;

[0291] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. When there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute Step 820; when there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute Step 821;

[0292] Step 820: Continue to apply an alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of decreasing the voltage or current amplitude of the currently applied alternating electric signal, and return to Step 812;

[0293] Step 821: Determine the number of over-temperature regions and execute Step 822, where the over-temperature region is the region containing the electrode unit whose temperature exceeds the preset temperature threshold t0, and the non-over-temperature region is the region where the temperatures of all its electrode units do not exceed the preset temperature threshold t0;

[0294] Step 822: Determine whether the number of over-temperature regions exceeds the preset number threshold. When the number of over-temperature regions exceeds the preset number threshold, execute Step 823; when the number of over-temperature regions does not exceed the preset number threshold, execute Step 826;

[0295] Step 823: Stop applying the alternating electric signal to each electrode unit 33 of the electrode sheet 13 and execute Step 824;

[0296] Step 824: Combine the control switch 54 electrically connected to the electrode sheet 13 with the bidirectional changeover switch 55 to obtain the temperatures of the electrode units 33 of the electrode sheet 13 and execute Step 825;

[0297] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. When there is no electrode unit 33 on the electrode sheet 13 with a temperature exceeding the first preset temperature t1, return to Step 811. When there is an electrode unit 33 on the electrode sheet 13 with a temperature exceeding the first preset temperature t1, return to Step 824;

[0298] Step 826: Distinguish the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 33 with a temperature exceeding the preset temperature threshold t0. When the area is the over-temperature area, execute Step 827. When the area is the non-over-temperature area, execute Step 828;

[0299] Step 827: Stop applying the alternating electric signal to the electrode units 33 in the over-temperature area and execute Step 835;

[0300] Step 828: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1, execute Step 829. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the electrode units 33 in the non-over-temperature area, execute Step 830;

[0301] Step 829: Continue to apply the alternating electric signal to the electrode units 33 in the non-over-temperature area of the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating electric signal and execute Step 835;

[0302] Step 830: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2, execute Step 831. When there is a temperature exceeding the second preset temperature t2 among the temperatures of the electrode units 33 in the non-over-temperature area, execute Step 832;

[0303] Step 831: Continue to apply the alternating electric signal to the electrode units 33 in the non-over-temperature area of the electrode sheet 13 by keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged and execute Step 835;

[0304] Step 832: Determine whether there is an electrode unit 33 with a temperature exceeding the third preset temperature t3 among the temperatures of the electrode units 33 in the non-over-temperature area. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the third preset temperature t3, execute Step 833. When there is a temperature exceeding the third preset temperature t3 among the temperatures of the electrode units 33 in the non-over-temperature area, execute Step 834;

[0305] Step 833: Continue to apply an alternating current signal to each electrode unit 33 in the non-overheating area of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating current signal, and execute Step 835;

[0306] Step 834: Continue to apply an alternating current signal to each electrode unit 33 in the non-overheating area of the electrode sheet 13 in a manner of further reducing the voltage or current amplitude of the currently applied alternating current signal, and execute Step 835;

[0307] Step 835: Combine the control of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperatures of the respective electrode units 33 of the electrode sheet 13, and select to execute Step 836 or Step 838. The temperatures of the respective electrode units 33 of the electrode sheet 13 include the temperatures of the respective electrode units 33 in the overheating area and the temperatures of the respective electrode units 33 in the non-overheating area;

[0308] Step 836: Determine whether the temperatures of all the electrode units 33 in the overheating area do not exceed the first preset temperature t1. When the temperatures of all the electrode units 33 in the overheating area do not exceed the first preset temperature t1, execute Step 837. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the respective electrode units 33 in the overheating area, return to Step 835;

[0309] Step 837: Re-determine this area as a non-overheating area and execute Step 838;

[0310] Step 838: Determine whether the temperatures of all the electrode units 33 in the acquired non-overheating area do not exceed the first preset temperature t1. When the temperatures of all the electrode units 33 in the non-overheating area do not exceed the first preset temperature t1, execute Step 839. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the respective electrode units 33 in the non-overheating area, execute Step 840;

[0311] Step 839: Continue to apply an alternating current signal to each electrode unit 33 in the non-overheating area in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal, and return to Step 812;

[0312] Step 840: Determine whether the temperatures of all the electrode units 33 in the acquired non-overheating area do not exceed the second preset temperature t2. When the temperatures of all the electrode units 33 in the non-overheating area do not exceed the second preset temperature t2, execute Step 841. When there is a temperature exceeding the second preset temperature t2 among the temperatures of the respective electrode units 33 in the non-overheating area, execute Step 842;

[0313] Step 841: Continue to apply the alternating current signal to each electrode unit 33 in the non-overtemperature area in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal unchanged, and return to Step 812;

[0314] Step 842: Determine whether the temperatures of all electrode units 33 in the obtained non-overtemperature area do not exceed the third preset temperature t3. When the temperatures of all electrode units 33 in the non-overtemperature area do not exceed the third preset temperature t3, execute Step 843. When there is a temperature in the temperatures of all electrode units 33 in the non-overtemperature area that exceeds the third preset temperature t3, execute Step 844;

[0315] Step 843: Continue to apply the alternating current signal to each electrode unit 33 in the non-overtemperature area in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal, and return to Step 812;

[0316] Step 844: Determine whether the temperatures of all electrode units 33 in the obtained non-overtemperature area do not exceed the preset temperature threshold t0. When the temperatures of all electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0, execute Step 845. When there is a temperature in the temperatures of all electrode units 33 in the non-overtemperature area that exceeds the preset temperature threshold t0, return to Step 821;

[0317] Step 845: Continue to apply the alternating current signal to each electrode unit 33 in the non-overtemperature area in a manner that further reduces the voltage or current amplitude of the currently applied alternating current signal, and return to Step 812.

[0318] Among them, the process of applying the alternating current signal to each electrode unit 33 of the corresponding electrode plate 13 by combining the control of the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode plate 13 in Step 811 is specifically as follows:

[0319] Disconnect all control switches 54 electrically connected to the corresponding electrode plate 13, and at the same time switch all bidirectional switches 55 electrically connected to the corresponding electrode plate 13 to the end that applies the alternating current signal to each electrode unit 33; or

[0320] Disconnect all control switches 54 electrically connected to the corresponding electrode plate 13, and at the same time switch all bidirectional switches 55 electrically connected to the corresponding electrode plate 13 to the end that makes each electrode unit 33 electrically connected to the alternating current power line 57; or

[0321] Disconnect all control switches 54 electrically connected to the corresponding electrode plate 13, and at the same time switch all bidirectional switches 55 electrically connected to the corresponding electrode plate 13 to their respective 2 ends.

[0322] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in step 812, step 824, and step 835 is specifically as follows:

[0323] Control the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, control each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from the end at which the alternating electric signal is applied to each electrode unit 33 to the end at which the temperature of each electrode unit 33 is collected in sequence in a time-sharing manner, and the remaining two-way switching switches 55 are all switched from the end at which the temperature of each electrode unit 33 is collected to the end at which the alternating electric signal is applied to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0324] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from its two ends, which apply the alternating electric signal to each electrode unit 33, to its one end in a time-sharing manner, and controlling the remaining two-way switching switches 55 to switch from its one end to its two ends, which apply the alternating electric signal to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0325] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52 in a time-division order, and the remaining two-way switching switches 55 to be switched from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57, and at the same time each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-division order to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0326] The power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and each of the two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal in a time-sharing manner, and the remaining two-way switching switches 55 switch from transmitting a direct current signal or a temperature detection signal to transmitting an alternating electric signal. At the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0327] The first preset temperature in step 813, step 825, step 828, step 836, and step 838 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 815, step 830, and step 840 is 40.4°C to 40.6°C, preferably 40.5°C; the third preset temperature in step 817, step 832, and step 842 is 40.7°C to 40.9°C, preferably 40.8°C; the preset temperature threshold in step 819 and step 844 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 822 is preferably 2.

[0328] The process of continuing to apply the alternating electric signal described in step 814, step 816, step 818, step 820, step 829, step 831, step 833, step 834, step 839, step 841, step 843, and step 845 is specifically as follows:

[0329] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to conduct the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0330] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to switch from its respective 1 end to its respective 2 end so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0331] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal so that both of its 2 ends are electrically connected to the alternating power supply line 57, thereby continuing to apply an alternating electrical signal to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal; or

[0332] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal so that its respective 2 ends are closed and 1 end is disconnected, thereby continuing to apply an alternating electrical signal to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal; or

[0333] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue to be applied with an alternating electrical signal so that the electrode unit 33 that needs to continue to be applied with an alternating electrical signal switches from transmitting a temperature detection signal to applying an alternating electrical signal.

[0334] The method of continuing to apply the alternating electrical signal by increasing the voltage or current amplitude of the currently applied alternating electrical signal in step 814, step 829, and step 839 is specifically to perform a step-up process on the currently applied alternating electrical signal at an increment of the DC voltage amplitude of 0.03 V per second and then continue to apply the alternating electrical signal.

[0335] The method of continuing to apply the alternating electrical signal by reducing the voltage or current amplitude of the currently applied alternating electrical signal in step 818, step 820, step 833, step 834, step 843, and step 845 is specifically to continue to apply the alternating electrical signal in a manner that is 5 V smaller than the voltage amplitude of the currently applied alternating electrical signal and lasts for 3 minutes.

[0336] The process of stopping applying the alternating electrical signal to each electrode unit 33 of the electrode plate 13 in step 823 is specifically as follows:

[0337] Control the bidirectional switching switch 55 electrically connected to the electrode plate 13 to disconnect the electrical connection between each electrode unit 33 of the electrode plate 13 and the alternating power supply line 57; or

[0338] Control the bidirectional switching switch 55 electrically connected to the electrode plate 13 to switch all from the end that makes each electrode unit 33 apply an alternating electrical signal to the end that makes each electrode unit 33 perform temperature acquisition; or

[0339] Control the bidirectional switching switch 55 electrically connected to the electrode plate 13 to switch all from the 2 ends that make each electrode unit 33 apply an alternating electrical signal to its 1 end; or

[0340] Control the bidirectional switch 55 electrically connected to the electrode patch 13 to switch the electrode patch 13 from the electrical connection of its respective electrode units 33 to the alternating current power line 57 to the electrical connection of its respective electrode units 33 to the corresponding ADC unit 52; or

[0341] Control the bidirectional switch 55 electrically connected to the electrode patch 13 to switch each electrode unit 33 of the electrode patch 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0342] The process of stopping applying an alternating current signal to each electrode unit 33 in the over-temperature area described in step 827 is specifically as follows:

[0343] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the alternating current power line 57; or

[0344] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all from the end that applies an alternating current signal to each electrode unit 33 in the over-temperature area to the end that performs temperature acquisition on each electrode unit 33 in the over-temperature area; or

[0345] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all from the 2 ends that apply an alternating current signal to each electrode unit 33 in the over-temperature area to its 1 end; or

[0346] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch each electrode unit 33 in the over-temperature area from its electrical connection to the alternating current power line 57 to its electrical connection to the corresponding ADC unit 52; or

[0347] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0348] When the tumor electric field treatment system 100 is in the standby state before starting to work, no alternating current signal is applied to the electrode unit 33. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the bidirectional switch 55 (one of 55-1 to 55-4) to switch to the 1 end in sequence, and the control switches 54 (54-1 to 54-5) are conducted respectively in sequence. The ADC unit 52 obtains the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 (33-1 to 33-20) respectively in sequence.

[0349] When the first control switch 54-1 is turned on, the control switches (54-2, 54-3, 54-4, 54-5) are all turned off, and when the bidirectional changeover switches (55-1 to 55-4) are sequentially placed at the 1 end, the ADC unit 52 receives the temperature detection signals of the temperature detection units 35 corresponding to the electrode units (33-1, 33-6, 33-11, 33-16).

[0350] When the second control switch 54-2 is turned on, the control switches (54-1, 54-3, 54-4, 54-5) are all turned off, and when the bidirectional changeover switches (55-1 to 55-4) are sequentially placed at the 1 end, the first detection channel A of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-1 and the electrode unit 33-2, the second detection channel B of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-6 and the electrode unit 33-7, the third detection channel C of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-11 and the electrode unit 33-12, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-16 and the electrode unit 33-17.

[0351] When the third control switch 54-3 is turned on, the control switches (54-1, 54-2, 54-4, 54-5) are all turned off, and when the bidirectional changeover switches (55-1 to 55-4) are sequentially placed at the 1 end, the first detection channel A of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-1, the electrode unit 33-2, and the electrode unit 33-3, the second detection channel B of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-6, the electrode unit 33-7, and the electrode unit 33-8, the third detection channel C of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-11, the electrode unit 33-12, and the electrode unit 33-13, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode unit 33-16, the electrode unit 33-17, and the electrode unit 33-18.

[0352] When the fourth control switch 54-4 is turned on, the control switches (54-1, 54-2, 54-3, 54-5) are all turned off, and when the bidirectional switching switches (55-1 to 55-4) are sequentially placed at the 1 end, the first detection channel A of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-1, 33-2, 33-3, and 33-4, the second detection channel B of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-6, 33-7, 33-8, and 33-9, the third detection channel C of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-11, 33-12, 33-13, and 33-14, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-16, 33-17, 33-18, and 33-19;

[0353] When the fifth control switch 54-5 is turned on, the control switches (54-1, 54-2, 54-3, 54-4) are all turned off, and when the bidirectional switching switches (55-1 to 55-4) are sequentially placed at the 1 end, the first detection channel A of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-1, 33-2, 33-3, 33-4, and 33-5, the second detection channel B of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-6, 33-7, 33-8, 33-9, and 33-10, the third detection channel C of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-11, 33-12, 33-13, 33-14, and 33-15, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33-16, 33-17, 33-18, 33-19, and 33-20. Thus, through the processing method described above, the temperature detection signals corresponding to each electrode unit 33 can be obtained.

[0354] The first controller 51 receives the temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33 (33-1 to 33-20) through the ADC unit 52, and transmits them to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38, and then controls or adjusts the alternating electric signals applied to the electrode units 33 through the second controller 37.

[0355] In the embodiments of the present application, it should be noted that when the bidirectional switch is controlled to conduct to terminal 1, the first switching end of the corresponding rectification switching unit is connected to the fixed end, and when the bidirectional switch is controlled to conduct to terminal 2, the second switching end of the corresponding rectification switching unit is connected to the fixed end.

[0356] Although the various operations are depicted in the drawings as occurring in a particular order, this should not be construed as requiring that the operations must occur in the particular order shown or in sequential order, nor should it be construed as requiring that all of the illustrated operations be performed to obtain the desired result.

[0357] Embodiment 2:

[0358] In the tumor electric field treatment system 100 shown in Embodiment 1, two adjacent electrode units 33 in part of the electrode sheet 13 are connected by a connecting band (not labeled). The connection methods of the 10 electrode units 33 on the left side of the electrode sheet 13 and the 10 electrode units 33 on the right side are asymmetric. Among the 10 electrode units 33 on the left side of the electrode sheet 13, 4 electrode units 33 are at the free ends, and among the 10 electrode units 33 on the right side of the electrode sheet 13, 5 electrode units 33 are at the free ends. Different from the tumor electric field treatment system 100 shown in Embodiment 1, referring to Figure 17 , another tumor electric field treatment system 100A is described below. Its main concept is the same as that of the above-mentioned tumor electric field treatment system 100, and the spatial arrangement of its electrode units 33A is the same as that of the electrode units 33 of the tumor electric field treatment system 100 shown in Embodiment 1. The difference is that: the connection method of the electrode units 33A in the electrode sheet 13A of this tumor electric field treatment system 100A is different. The connection methods of the 10 electrode units 33A on the left side of the electrode sheet 13A and the 10 electrode units 33A on the right side are symmetric. Among the 10 electrode units 33A on the left side of the electrode sheet 13A, 4 electrode units 33A are at the free ends, and among the 10 electrode units 33A on the right side of the electrode sheet 13A, 4 electrode units 33A are at the free ends. Specifically, along the column upward, only the adjacent two electrode units 33 in the third column and the fourth column are connected by a connecting band (not labeled), and the adjacent two electrode units 33 in the other four columns are not connected by a connecting band. A bridging part (not labeled) connects between the two connecting bands (not labeled) opposite to each other along the column.

[0359] Among them, the other contents in this embodiment are similar to those in the above-mentioned Embodiment 1 and will not be elaborated here.

[0360] Embodiment 3:

[0361] In the tumor electric field therapy system 100 shown in Embodiment 1, each electrode sheet 13 includes 20 electrode units 33. Different from the tumor electric field therapy system 100 shown in Embodiment 1, referring to Figure 18 and Figure 19 , another tumor electric field therapy system 100B is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100, but the difference is that each electrode sheet 13B in the electrode sheet 13B of the tumor electric field therapy system 100B includes 13 electrode units 33B, and there is no electrode unit 33B at the free end in each electrode sheet 13B, and the number of electrode units 33B included in each row group and each column group of each electrode sheet 13B is different. Specifically, these 13 electrode units 33B are arranged in a five-row group and a five-column group in the spatial structure. Each of the first row and the fifth row includes 2 electrode units 33B, and the 2 electrode units 33B in each row are respectively located in the second column and the fourth column; each of the second row to the fourth row includes 3 electrode units 33B, and the 3 electrode units 33B in each row are respectively located in the first column, the third column and the fifth column. Adjacent two electrode units 33B in each row of the above five rows of electrode units 33B are connected by a connecting band (not labeled). Adjacent two electrode units 33B in each of the first column, the third column and the fifth column are connected by a connecting band (not labeled). The electrode unit 33B located in the second column of the first row is respectively connected to the electrode units 33B located in the first column of the second row and the third column of the first row by a connecting band (not labeled); the electrode unit 33B located in the fourth column of the first row is respectively connected to the electrode units 33B located in the third column of the second row and the fifth column of the first row by a connecting band (not labeled); the electrode unit 33B located in the second column of the fifth row is respectively connected to the electrode units 33B located in the first column of the fourth row and the third column of the fourth row by a connecting band (not labeled); the electrode unit 33B located in the fourth column of the fifth row is respectively connected to the electrode units 33B located in the third column of the fourth row and the fifth column of the fourth row by a connecting band (not labeled).

[0362] Figure 19 For Figure 18Schematic diagram of the circuit connection between the electrode patch 13B of the tumor electro-field therapy system 100B shown and the adapter 20B. A plurality of electrode units 33B are configured as a plurality of row groups and a plurality of column groups in terms of circuit connection. In this embodiment, 13 electrode units 33B are provided on each electrode patch 13B. The 13 electrode units 33B are sorted and grouped in the order of 1 to 13 in terms of circuit connection. The electrode units 33-1B to 33-13B are divided into three row groups and five column groups, that is, the 13 electrode units 33B are arranged in a three-row and five-column layout in terms of circuit connection. Both the first row group and the second row group include 5 electrode units 33B, the third row group includes 3 electrode units 33B, the first column group to the third column group all include 3 electrode units 33B, and the fourth column group to the fifth column group all include 2 electrode units 33B.

[0363] The electrode patch 13B includes 5 ground wires 18B, namely the first ground wire 18-1B, the second ground wire 18-2B, the third ground wire 18-3B, the fourth ground wire 18-4B and the fifth ground wire 18-5B. The 5 ground wires 18B are respectively arranged in one-to-one correspondence with the five column groups. Among the 5 column groups of the electrode patch 13B, the first column group includes the electrode unit 33-1B, the electrode unit 33-6B, and the electrode unit 33-11B; the second column group includes the electrode unit 33-2B, the electrode unit 33-7B, and the electrode unit 33-12B; the third column group includes the electrode unit 33-3B, the electrode unit 33-8B, and the electrode unit 33-13B; the fourth column group includes the electrode unit 33-4B and the electrode unit 33-9B; the fifth column group includes the electrode unit 33-5B and the electrode unit 33-10B. Specifically, the first ground wire 18-1B is used to ground the ground terminals of the respective corresponding temperature detection units 35B in the electrode units 33-1B, 33-6B, and 33-11B in the first column group; the second ground wire 18-2B is used to ground the ground terminals of the respective corresponding temperature detection units 35B in the electrode units 33-2B, 33-7B, and 33-12B in the second column group; the third ground wire 18-3B is used to ground the ground terminals of the respective corresponding temperature detection units 35B in the electrode units 33-3B, 33-8B, and 33-13B in the third column group; the fourth ground wire 18-4B is used to ground the ground terminals of the respective corresponding temperature detection units 35B in the electrode units 33-4B and 33-9B in the fourth column group; the fifth ground wire 18-5B is used to ground the ground terminals of the respective corresponding temperature detection units 35B in the electrode units 33-5B and 33-10B in the fifth column group.

[0364] Different from Embodiment 1 or Embodiment 2 above, the multi-purpose signal line 19B in this embodiment only includes three multi-purpose signal lines, namely the first multi-purpose signal line 19-1B, the second multi-purpose signal line 19-2B, and the third multi-purpose signal line 19-3B. The first multi-purpose signal line 19-1B, the second multi-purpose signal line 19-2B, and the third multi-purpose signal line 19-3B are respectively arranged in one-to-one correspondence with three row groups of the electrode units 33B of the electrode plate 13B. Specifically, five electrode units 33B from electrode unit 33-1B to electrode unit 33-5B are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16B, and the temperature detection units 35B of their respective electrode units 33B are connected in series and then connected to the first switching end 1 of the corresponding rectifying switching unit 16B. The fixed end 3 of this rectifying switching unit 16B is connected to the first multi-purpose signal line 19-1B; five electrode units 33B from electrode unit 33-6B to electrode unit 33-10B are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16B, and the temperature detection units 35B of their respective electrode units 33B are connected in series and then connected to the first switching end 1 of the corresponding rectifying switching unit 16B. The fixed end 3 of this rectifying switching unit 16B is connected to the second multi-purpose signal line 19-2B; three electrode units 33B from electrode unit 33-11B to electrode unit 33-13B are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16B, and the temperature detection units 35B of their respective electrode units 33B are connected in series and then connected to the first switching end 1 of the corresponding rectifying switching unit 16B. The fixed end 3 of this rectifying switching unit 16B is connected to the third multi-purpose signal line 19-3B. Of course, in some examples, the multi-purpose signal line 19B may also include a four-way multi-purpose signal line, and the fourth multi-purpose signal line is not electrically connected to the signal end of any temperature detection unit 35B.

[0365] Specifically, in this embodiment, the multiple control switches 54B in the corresponding group of control switches 54B are respectively the first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B. The first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B respectively control the closing or opening of the corresponding ground wires 18B of the same electrode plate 13B one by one. The first control switch 54-1B is used to control the closing or opening of the first ground wire 18-1B of the corresponding electrode plate 13B, and further cooperate with the corresponding group of bidirectional switching switches 55B and the corresponding rectifier switching unit 16B to control the power-on and power-off of the respective temperature detection units 35B corresponding to the three electrode units 33B, namely the electrode unit 33-1B, the electrode unit 33-6B, and the electrode unit 33-11B, in the first column group of the electrode plate 13B; the second control switch 54-2B is used to control the closing or opening of the second ground wire 18-2B of the electrode plate 13B, and further cooperate with the corresponding group of bidirectional switching switches 55B and the corresponding rectifier switching unit 16B to control the power-on and power-off of the temperature detection units 35B corresponding to multiple electrode units 33B (the multiple electrode units can be respectively: the electrode unit 33-1B and the electrode unit 33-2B, the electrode unit 33-6B and the electrode unit 33-7B, the electrode unit 33-11B and the electrode unit 33-12B) in the first column group and the second column group of the electrode plate 13B; the third control switch 54-3B is used to control the closing or opening of the third ground wire 18-3B of the electrode plate 13B, and further cooperate with the corresponding group of bidirectional switching switches 55B and the corresponding rectifier switching unit 16B to control the power-on and power-off of the respective temperature detection units 35B corresponding to multiple electrode units 33B (the electrode units 33-1B to 33-3B, the electrode units 33-6B to 33-8B, the electrode units 33-11B to 33-13B) in the first column group, the second column group, and the third column group of the electrode plate 13B. The fourth control switch 54-4B and the fifth control switch 54-5B are the same in principle and will not be elaborated here.

[0366] Taking the electrical connection between an electrode sheet 13B and an adapter 20B as an example, among the multiple two-way switching switches 55B in the corresponding group of two-way switching switches 55B are the first two-way switching switch 55-1B, the second two-way switching switch 55-2B, the third two-way switching switch 55-3B, and the fourth two-way switching switch 55-4B respectively. The first two-way switching switch 55-1B, the second two-way switching switch 55-2B, and the third two-way switching switch 55-3B respectively control the switching of the corresponding one of the multiplexed signal lines 19B of the same electrode sheet 13B between transmitting an alternating current signal and transmitting a temperature detection signal. Specifically, the first two-way switching switch 55-1B is used to control the switching of the first multiplexed signal line 19-1B of the corresponding electrode sheet 13B between transmitting an alternating current signal and transmitting a temperature detection signal, and further control the switching between the conduction of each electrode unit 33B of the electrode units 33-1B to 33-5B in the first row group of the electrode sheet 13B and the conduction of the signal terminals of the corresponding temperature detection units 35B of the electrode units 33-1B to 33-5B in the first row group, and cooperate with the corresponding first control switch 54-1B, second control switch 54-2B, third control switch 54-3B, fourth control switch 54-4B, and fifth control switch 54-5B, so that the first row of electrode units 33-1B to 33-5B transmits an alternating current signal to the patient or the temperature detection signals (such as analog temperature signals) detected by one or more corresponding combinations of the temperature detection units 35B corresponding to these electrode units 33B are respectively sampled and output to the corresponding ADC unit 52B; the second two-way switching switch 55-2B is used to control the switching of the second multiplexed signal line 19-2B of the corresponding electrode sheet 13B between transmitting an alternating current signal and transmitting a temperature detection signal, and further control the switching between the conduction of each electrode unit 33B of the electrode units 33-6B to 33-10B in the second row group of the electrode sheet 13B and the conduction of the signal terminals of the corresponding temperature detection units 35B of the electrode units 33-6B to 33-10B in the second row group, and cooperate with the corresponding first control switch 54-1B, second control switch 54-2B, third control switch 54-3B, fourth control switch 54-4B, and fifth control switch 54-5B, so that the second row of electrode units 33-6B to 33-10B transmits an alternating current signal to the patient or the temperature detection signals (such as analog temperature signals) detected by one or more corresponding combinations of the temperature detection units 35B corresponding to these electrode units 33B are respectively sampled and output to the corresponding ADC unit 52B;The third bidirectional switch 55-3B is used to control the switching of the third dual-purpose signal line 19-3B of the corresponding electrode plate 13B between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each electrode unit 33B of the electrode units 33-11B to 33-13B in the third row group of the electrode plate 13B and the switching between the conduction of the signal terminals of the corresponding temperature detection units 35B of the electrode units 33-11B to 33-13B in the third row group, and cooperating with the corresponding first control switch 54-1B, second control switch 54-2B, and third control switch 54-3B, so that the third row of electrode units 33-11B to 33-13B transmit an alternating current signal to the patient or the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35B of these electrode units 33B are respectively sampled and output to the corresponding ADC unit 52B; The fourth bidirectional switch 55-4B is not corresponding to any row group (not connected to any dual-purpose signal line), so there is no need to control the signal through the fourth bidirectional switch 55-4B.

[0367] Among them, the other content in this embodiment is similar to that of the above-mentioned Embodiment 1, and will not be elaborated here.

[0368] Embodiment 4:

[0369] In the tumor electric field therapy system 100B shown in Embodiment 3, the electrode units 33B at the ends among the 13 electrode units 33B in each electrode plate 13B are not freely arranged. Different from the tumor electric field therapy system 100B shown in Embodiment 3, referring to Figure 20 , another tumor electric field therapy system 100C, whose main concept is the same as that of the above-mentioned tumor electric field therapy system 100B, the difference is that: the connection method of the connecting band (not labeled) in the electrode plate 13C of the tumor electric field therapy system 100C is different, and the 13 electrode units 33C include 2 electrode units 33C at the free ends. Specifically, Figure 20 In the electrode plate 13C of the tumor electric field therapy system 100C shown, there is no connecting band between the electrode unit 33C in the second column of the first row and the 2 electrode units 33C in the fourth column of the first row and the first column of the second row; there is no connecting band between the electrode unit 33C in the fourth column of the fifth row and the 2 electrode units 33C in the second column of the fifth row and the fifth column of the fourth row; there is no connecting band between the 2 electrode units 33C in the fifth column of the second row and the fifth column of the third row; there is no connecting band between the 2 electrode units 33C in the fifth column of the second row and the fifth column of the third row. The connecting band (not shown) of the electrode plate 100C is arranged in this way to form corresponding open spaces and free ends, which is convenient for application.

[0370] Among them, the other content in this embodiment is similar to that in the above-mentioned Embodiment 3, and will not be elaborated here.

[0371] Embodiment 5:

[0372] In the tumor electrotherapy system 100B shown in Embodiment 3, the 13 electrode units 33 in each electrode sheet 13B are connected by 22 connection bands. Different from the tumor electrotherapy system 100B shown in Embodiment 3, referring to Figure 21 , another tumor electrotherapy system 100D, whose main concept is the same as that of the above-mentioned tumor electrotherapy system 100B, is different in that: the 13 electrode units 33D in each electrode sheet 13D of this tumor electrotherapy system 100D are connected by 18 connection bands. Specifically, Figure 21 In the electrode sheet 13D of the tumor electrotherapy system 100D shown, no connection band is provided between adjacent two electrode units 33D in the first row and the fifth row; no connection band is provided between the two electrode units 33D in the first column of the second row and the third column of the second row; no connection band is provided between the two electrode units 33D in the third column of the fourth row and the fifth column of the fourth row. The connection bands (not shown) of the electrode sheet 100D are arranged in this way to form corresponding open spaces and free ends, which is convenient for application.

[0373] Among them, the other content in this embodiment is similar to that in the above-mentioned Embodiment 3, and will not be elaborated here.

[0374] Embodiment 6:

[0375] Different from the tumor electrotherapy system 100B shown in Embodiment 3, referring to Figure 22 , another tumor electrotherapy system 100E is described below. Its main concept is the same as that of the above-mentioned tumor electrotherapy system 100B, but the difference is that the number of electrode units 33E included in each row group and each column group of each electrode sheet 13E of this tumor electrotherapy system 100E is different in circuit connection.

[0376] Figure 22Schematic diagram of the circuit connection between the electrode patch 13E and the adapter 20E of the tumor electrotherapy system 100E. A plurality of electrode units 33E are configured into a plurality of row groups and a plurality of column groups. In this embodiment, 13 electrode units 33E are provided on each electrode patch 13E, and the 13 electrode units 33E are sorted and grouped in the order of 1 to 13 in terms of circuit connection. The electrode units 33-1E to 33-13E are divided into four row groups and four column groups, that is, the 13 electrode units 33E are arranged in a four-row and four-column layout in terms of circuit connection. Each of the first to third row groups includes 4 electrode units 33E, and the fourth row group includes 1 electrode unit 33E. The first column group includes 4 electrode units 33E, and the second to fourth column groups each include 3 electrode units 33E.

[0377] The electrode sheet 13E includes four ground wires 18E, namely the first ground wire 18-1E, the second ground wire 18-2E, the third ground wire 18-3E, and the fourth ground wire 18-4E. The first ground wire 18-1E, the second ground wire 18-2E, the third ground wire 18-3E, and the fourth ground wire 18-4E are respectively arranged in one-to-one correspondence with four column groups. Among the four column groups of the electrode sheet 13E, the first column group includes electrode units 33-1E, 33-5E, 33-9E, and 33-13E; the second column group includes electrode units 33-2E, 33-6E, and 33-10E; the third column group includes electrode units 33-3E, 33-7E, and 33-11E; the fourth column group includes electrode units 33-4E, 33-8E, and 33-12E. Specifically, the first ground wire 18-1E is used to ground the ground terminals of the respective corresponding temperature detection units 35E in the electrode units 33-1E, 33-5E, 33-9E, and 33-13E in the first column group; the second ground wire 18-2E is used to ground the temperature detection units 35E connected in series in the electrode units 33-1E and 33-2E, the temperature detection units 35E connected in series in the electrode units 33-5E and 33-6E, and the temperature detection units 35E connected in series in the electrode units 33-9E and 33-10E respectively; the third ground wire 18-3E is used to ground the temperature detection units 35E connected in series from the electrode unit 33-1E to the electrode unit 33-3E, the temperature detection units 35E connected in series from the electrode unit 33-5E to the electrode unit 33-7E, and the temperature detection units 35E connected in series from the electrode unit 33-9E to the electrode unit 33-11E respectively; the fourth ground wire 18-4E is used to ground the temperature detection units 35E connected in series from the electrode unit 33-1E to the electrode unit 33-4E, the temperature detection units 35E connected in series from the electrode unit 33-5E to the electrode unit 33-8E, and the temperature detection units 35E connected in series from the electrode unit 33-9E to the electrode unit 33-12E respectively. Of course, in some examples, the multiple ground wires 18E may also include five ground wires, and the fifth ground wire is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth ground wire does not short-circuit and ground each corresponding temperature detection unit in any column group.

[0378] In this embodiment, the multi-purpose signal line 19E includes a first multi-purpose signal line 19-1E, a second multi-purpose signal line 19-2E, a third multi-purpose signal line 19-3E, and a fourth multi-purpose signal line 19-4E, which are respectively arranged in one-to-one correspondence with four row groups of the electrode units 33E of the electrode plate 13E. Specifically, the four electrode units 33E from electrode unit 33-1E to electrode unit 33-4E are connected in parallel to the second switching end 2 of the corresponding rectifying and switching unit 16E, and the temperature detection units 35E of their respective electrode units 33E are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16E. The fixed end 3 of this rectifying and switching unit 16E is connected to the first multi-purpose signal line 19-1E; the four electrode units 33E from electrode unit 33-5E to electrode unit 33-8E are connected in parallel to the second switching end 2 of the corresponding rectifying and switching unit 16E, and the temperature detection units 35E of their respective electrode units 33E are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16E. The fixed end 3 of this rectifying and switching unit 16E is connected to the second multi-purpose signal line 19-2E; the four electrode units 33E from electrode unit 33-9E to electrode unit 33-12E are connected in parallel to the second switching end 2 of the corresponding rectifying and switching unit 16E, and the temperature detection units 35E of their respective electrode units 33E are connected in series and then connected to the first switching end 1 of the corresponding rectifying and switching unit 16E. The fixed end 3 of this rectifying and switching unit 16E is connected to the third multi-purpose signal line 19-3E; the electrode unit 33-13E is connected to the second switching end 2 of the corresponding rectifying and switching unit 16E, and its corresponding temperature detection unit 35E is connected to the first switching end 1 of the corresponding rectifying and switching unit 16E. The fixed end 3 of this rectifying and switching unit 16E is connected to the fourth multi-purpose signal line 19-4E.

[0379] Specifically, in this embodiment, the multiple control switches 54E are respectively the first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, the fourth control switch 54-4E, and the fifth control switch 54-5E. The first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E respectively control the closing or opening of the corresponding ground wires 18E of the same electrode plate 13E one by one. The first control switch 54-1E is used to control the closing or opening of the first ground wire 18-1E of the corresponding electrode plate 13E, and then can cooperate with the corresponding group of bidirectional switching switches 55E and the corresponding rectification switching unit 16E to control the energization and de-energization of the temperature detection units 35E corresponding to the four electrode units 33E, namely the electrode unit 33-1E, the electrode unit 33-5E, the electrode unit 33-9E, and the electrode unit 33-13E, in the first column group of the electrode plate 13E; the second control switch 54-2E is used to control the closing or opening of the second ground wire 18-2E of the electrode plate 13E, and then can cooperate with the corresponding group of bidirectional switching switches 55E and the corresponding rectification switching unit 16E to control the energization and de-energization of the temperature detection units 35E corresponding to multiple electrode units (the multiple electrode units can be respectively: the electrode unit 33-1E and the electrode unit 33-2E, the electrode unit 33-5E and the electrode unit 33-6E, the electrode unit 33-9E and the electrode unit 33-10E) in the first column group and the second column group of the electrode plate 13E; the third control switch 54-3E is used to control the closing or opening of the third ground wire 18-3E of the electrode plate 13E, and then can cooperate with the corresponding group of bidirectional switching switches 55E and the corresponding rectification switching unit to control the energization and de-energization of the temperature detection units 35E corresponding to multiple electrode units (the multiple electrode units can be respectively: the electrode unit 33-1E to the electrode unit 33-3E, the electrode unit 33-5E to the electrode unit 33-7E, the electrode unit 33-9E to the electrode unit 33-11E) in the first column group, the second column group, and the third column group of the electrode plate 13E; the fourth control switch 54-4E is the same by analogy and will not be elaborated here; the fifth control switch 54-5E is not connected to any ground wire, and the fifth control switch 54-5E is not used for signal control.

[0380] Taking the electrical connection between an electrode plate 13E and an adapter 20E as an example, among the corresponding group of bidirectional switches 55E, multiple bidirectional switches 55E are respectively the first bidirectional switch 55-1E, the second bidirectional switch 55-2E, the third bidirectional switch 55-3E, and the fourth bidirectional switch 55-4E. The first bidirectional switch 55-1E, the second bidirectional switch 55-2E, the third bidirectional switch 55-3E, and the fourth bidirectional switch 55-4E respectively control the switching of the corresponding one of the multiplexed signal lines 19E of the same electrode plate 13E between transmitting an alternating current signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 55-1E is used to control the switching of the first multiplexed signal line 19-1E of the corresponding electrode plate 13E between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E of the electrode units 33-1E to 33-4E in the first row group of the electrode plate 13E and the conduction of the signal terminals of the corresponding temperature detection units of the electrode units 33-1E to 33-4E in the first row group, and cooperating with the corresponding first control switch 54-1E, second control switch 54-2E, third control switch 54-3E, and fourth control switch 54-4E, so that the first row of electrode units 33-1E to 33-4E transmits an alternating current signal to the patient or enables the temperature detection signals (such as analog temperature signals) detected by one or more corresponding combinations of the temperature detection units 35E corresponding to these electrode units 33E to be sampled and output to the corresponding ADC unit 52E respectively; the second bidirectional switch 55-2E is used to control the switching of the second multiplexed signal line 19-2E of the corresponding electrode plate 13E between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E of the electrode units 33-5E to 33-8E in the second row group of the electrode plate 13E and the conduction of the signal terminals of the corresponding temperature detection units 35E of the electrode units 33-5E to 33-8E in the second row group, and cooperating with the corresponding first control switch 54-1E, second control switch 54-2E, third control switch 54-3E, and fourth control switch 54-4E, so that the second row of electrode units 33-5E to 33-8E transmits an alternating current signal to the patient or enables the temperature detection signals (such as analog temperature signals) detected by one or more corresponding combinations of the temperature detection units 35E corresponding to these electrode units 33E to be sampled and output to the corresponding ADC unit 52E respectively;The third bidirectional switch 55-3E is used to control the switching of the third dual-purpose signal line 19-3E of the corresponding electrode plate 13E between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E of the electrode units 33-9E to 33-12E in the third row group of the electrode plate 13E and the conduction of the signal terminals of the corresponding temperature detection units 35E of the electrode units 33-9E to 33-12E in the third row group. It cooperates with the corresponding first control switch 54-1E, second control switch 54-2E, third control switch 54-3E, and fourth control switch 54-4E to enable the third row electrode units 33-9E to 33-12E to transmit an alternating current signal to the patient or to sample and output the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35E of these electrode units 33E to the corresponding ADC unit 52E respectively; The fourth bidirectional switch 55-4E is used to control the switching of the fourth dual-purpose signal line 19-4E of the corresponding electrode plate 13E between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the switching between the conduction of the electrode unit 33-13E in the fourth row group of the electrode plate 13E and the conduction of the signal terminal of the temperature detection unit 35E corresponding to the electrode unit 33-13E in the fourth row group. It cooperates with the corresponding first control switch 54-1E to enable the fourth row electrode unit 33-13E to transmit an alternating current signal to the patient or to sample and output the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35E of these electrode units 33E to the corresponding ADC unit 52E respectively.

[0381] Among them, the other content in this embodiment is similar to that of the above-mentioned Embodiment 3 and will not be elaborated here.

[0382] Embodiment 7:

[0383] Different from the tumor electric field therapy system 100E shown in Embodiment 6, referring to Figure 23 , another tumor electric field therapy system 100F is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100E, but the difference is that the number of electrode units 33F included in each row group and each column group in the circuit connection of each electrode plate 13E of the tumor electric field therapy system 100F is different.

[0384] Figure 23Schematic diagram of the circuit connection between the electrode patch 13F of the tumor electrotherapy system 100F and the adapter 20F. A plurality of electrode units 33F are configured into a plurality of row groups and a plurality of column groups. In this embodiment, 13 electrode units 33F are provided on each electrode patch 13F, and the 13 electrode units 33F are sorted and grouped in the order of 1 to 13 in terms of circuit connection. The electrode units 33-1F to 33-13F are divided into four row groups and four column groups, that is, the 13 electrode units 33F are arranged in a four-row and four-column pattern in terms of circuit connection. The first row group includes 4 electrode units 33F, and each of the second to fourth row groups includes 3 electrode units 33F. Each of the first to third column groups includes 4 electrode units 33F, and the fourth column group includes 1 electrode unit 33F.

[0385] The electrode patch 13F includes 4 ground wires 18F, namely the first ground wire 18-1F, the second ground wire 18-2F, the third ground wire 18-3F, and the fourth ground wire 18-4F. The first ground wire 18-1F, the second ground wire 18-2F, the third ground wire 18-3F, and the fourth ground wire 18-4F are respectively arranged in one-to-one correspondence with the four column groups. Of course, in some examples, the multiple ground wires 18F may also include five ground wires, and the fifth ground wire is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth ground wire does not short-circuit and ground each corresponding temperature detection unit in any column group. The multiple control switches 54F are respectively the first control switch 54-1F, the second control switch 54-2F, the third control switch 54-3F, the fourth control switch 54-4F, and the fifth control switch 54-5F. The first control switch 54-1F, the second control switch 54-2F, the third control switch 54-3F, and the fourth control switch 54-4F respectively control the closing or opening of the corresponding ground wire 18F of the same electrode patch 13F. The fifth control switch 54-5F is not connected to any ground wire, and the fifth control switch 54-5F is not used for signal control.

[0386] The multiple multi-purpose signal lines 19F include 4 multi-purpose signal lines, namely the first multi-purpose signal line 19-1F, the second multi-purpose signal line 19-2F, the third multi-purpose signal line 19-3F, and the fourth multi-purpose signal line 19-4F, which are respectively arranged in one-to-one correspondence with the four row groups of the electrode units 33F. The multiple bidirectional switching switches 55F are respectively the first bidirectional switching switch 55-1F, the second bidirectional switching switch 55-2F, the third bidirectional switching switch 55-3F, and the fourth bidirectional switching switch 55-4F. The first bidirectional switching switch 55-1F, the second bidirectional switching switch 55-2F, the third bidirectional switching switch 55-3F, and the fourth bidirectional switching switch 55-4F respectively control the switching between transmitting an alternating current signal and transmitting a temperature detection signal of the corresponding one of the multi-purpose signal lines 19F in the multiple multi-purpose signal lines 19F of the same electrode patch 13F.

[0387] It can be understood that in other embodiments of the present application, such as Figures 23A to 23C shown, each electrode sheet 13 may further include 12 electrode units 33, and the number of electrode units 33 included in each row group and each column group is different. As Figure 23A shown, the 12 electrode units 33I are sorted and grouped in the order of 1 to 12 in terms of circuit connection. The electrode units 33-1I to electrode units 33-12I are divided into three row groups and five column groups, that is, the 12 electrode units 33I are arranged in a three-row and five-column layout in terms of circuit connection. The first row group and the second row group each include 5 electrode units 33I, the third row group includes 2 electrode units 33I, the first column group to the second column group each include 3 electrode units 33I, and the third column group to the fifth column group each include 2 electrode units 33I. As Figure 23B shown, the 12 electrode units 33J are sorted and grouped in the order of 1 to 12 in terms of circuit connection. The electrode units 33-1J to electrode units 33-12J are divided into three row groups and four column groups, that is, the 12 electrode units 33J are arranged in a three-row and four-column layout in terms of circuit connection. The first row group to the third row group each include 4 electrode units 33J, and the first column group to the fourth column group each include 3 electrode units 33J. As Figure 23C shown, the 12 electrode units 33K are sorted and grouped in the order of 1 to 12 in terms of circuit connection. The electrode units 33-1K to electrode units 33-12K are divided into four row groups and three column groups, that is, the 12 electrode units 33K are arranged in a four-row and three-column layout in terms of circuit connection. The first row group to the fourth row group each include 3 electrode units 33K, and the first column group to the third column group each include 4 electrode units 33K.

[0388] Among them, other contents in this embodiment are similar to those in the above Embodiment 3 and will not be elaborated here.

[0389] Embodiment 8:

[0390] Different from the tumor electric field treatment systems 100B, 100C, 100D, 100E, and 100F shown in Embodiments 3 to 7, referring to Figure 24 and Figure 25 , another tumor electric field treatment system 100G is described below. Its main concept is the same as that of the above tumor electric field treatment systems 100B, 100C, 100D, 100E, or 100F, except that: each electrode sheet 13G in the electrode sheet 13G of the tumor electric field treatment system 100G includes 9 electrode units 33G.

[0391] Figure 25 For Figure 24 the circuit connection schematic diagram of the electrode sheet 13G of the tumor electric field treatment system 100G shown.

[0392] A plurality of electrode units 33G are configured into a plurality of row groups and a plurality of column groups. In this embodiment, there are 9 electrode units 33G provided on each electrode sheet 13G. The 9 electrode units 33G are sorted and grouped in the order of 1 to 9 in terms of circuit connection. The electrode unit 33-1G to the electrode unit 33-9G are divided into three row groups and four column groups. That is, the 9 electrode units 33G are arranged in a three-row and four-column layout in terms of circuit connection. Each of the first row group to the second row group includes 4 electrode units 33G, and the third row group includes 1 electrode unit 33G. The first column group includes 3 electrode units 33G, and each of the second column group to the fourth column group includes 2 electrode units 33G.

[0393] The electrode sheet 13G includes 4 ground wires 18G, namely the first ground wire 18-1G, the second ground wire 18-2G, the third ground wire 18-3G, and the fourth ground wire 18-4G. The first ground wire 18-1G, the second ground wire 18-2G, the third ground wire 18-3G, and the fourth ground wire 18-4G are respectively arranged in one-to-one correspondence with the four column groups of the electrode units 33G. Of course, in some examples, the multiple ground wires 18G may also include five ground wires, and the fifth ground wire is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth ground wire does not short-circuit and ground each corresponding temperature detection unit in any column group. The multiple control switches 54G are respectively the first control switch 54-1G, the second control switch 54-2G, the third control switch 54-3G, the fourth control switch 54-4G, and the fifth control switch 54-5G. The first control switch 54-1G, the second control switch 54-2G, the third control switch 54-3G, and the fourth control switch 54-4G respectively control the closing or opening of the corresponding ground wires 18G of the same electrode sheet 13G. The fifth control switch 54-5G is not connected to any ground wire, and the fifth control switch 54-5G is not used for signal control.

[0394] The multi-purpose signal line 19G includes three two-purpose signal lines, namely the first two-purpose signal line 19-1G, the second two-purpose signal line 19-2G, and the third two-purpose signal line 19-3G. The first two-purpose signal line 19-1G, the second two-purpose signal line 19-2G, and the third two-purpose signal line 19-3G are respectively arranged in one-to-one correspondence with three row groups of the electrode unit 33G. Of course, in some examples, the multi-purpose signal line 19G may also include four two-purpose signal lines, where the fourth two-purpose signal line is not electrically connected to the signal terminals of any temperature detection units. The multiple bidirectional switching switches 55G are respectively the first bidirectional switching switch 55-1G, the second bidirectional switching switch 55-2G, the third bidirectional switching switch 55-3G, and the fourth bidirectional switching switch 55-4G. The first bidirectional switching switch 55-1G, the second bidirectional switching switch 55-2G, and the third bidirectional switching switch 55-3G respectively control the switching of the corresponding one two-purpose signal line 19G in the multi-purpose signal line 19G of the same electrode plate 13G between transmitting an alternating current signal and transmitting a temperature detection signal. The fourth bidirectional switching switch 55-4G is not connected to any two-purpose signal line, and the fourth bidirectional switching switch 55-4G is not used for signal control.

[0395] Among them, the other content in this embodiment is similar to that in the above Embodiment 1, and will not be elaborated here.

[0396] Embodiment 9:

[0397] Different from the tumor electric field treatment system 100G shown in Embodiment 8, referring to Figure 26 , another tumor electric field treatment system 100H is described below. Its main concept is the same as that of the above tumor electric field treatment system 100G, but the difference is that the number of electrode units 33H included in each row group and each column group in the circuit connection of each electrode plate 13H of the tumor electric field treatment system 100H is different.

[0398] Figure 26 Schematic diagram of the circuit connection between the electrode plate 13H of the shown tumor electric field treatment system 100H and the adapter 20H.

[0399] The multiple electrode units 33H are configured into multiple row groups and multiple column groups. In this embodiment, each electrode plate 13H is provided with 9 electrode units 33H. The 9 electrode units 33H are sorted and grouped in the order of 1 to 9 in the circuit connection. The electrode units 33-1H to 33-9H are divided into three row groups and three column groups, that is, the 9 electrode units 33H are arranged in a three-row and three-column layout in the circuit connection. Each row group includes 3 electrode units 33H, and each column group includes 3 electrode units 33H.

[0400] The electrode sheet 13H includes three ground wires 18H, namely the first ground wire 18-1H, the second ground wire 18-2H, and the third ground wire 18-3H. The first ground wire 18-1H, the second ground wire 18-2H, and the third ground wire 18-3H are respectively arranged in one-to-one correspondence with three column groups of the electrode unit 33H. Of course, in some examples, the multiple ground wires 18H may also include four ground wires or five ground wires, where the fourth ground wire and / or the fifth ground wire are not electrically connected to the ground terminals of any temperature detection units, that is, the fourth ground wire and / or the fifth ground wire do not short-circuit and ground each corresponding temperature detection unit in any column group. The multiple control switches 54H are respectively the first control switch 54-1H, the second control switch 54-2H, the third control switch 54-3H, the fourth control switch 54-4H, and the fifth control switch 54-5H. The first control switch 54-1H, the second control switch 54-2H, and the third control switch 54-3H respectively control the closing or opening of the corresponding ground wires 18H of the same electrode sheet 13H. The fourth control switch 54-4H and the fifth control switch 54-5H are not connected to any ground wires, and the fourth control switch 54-4H and the fifth control switch 54-5H are not used for signal control.

[0401] The multi-purpose signal line 19H includes three two-purpose signal lines, namely the first two-purpose signal line 19-1H, the second two-purpose signal line 19-2H, and the third two-purpose signal line 19-3H. The first two-purpose signal line 19-1H, the second two-purpose signal line 19-2H, and the third two-purpose signal line 19-3H are respectively arranged in one-to-one correspondence with three row groups of the electrode unit 33H. Of course, in some examples, the multi-purpose signal line 19H may also include four two-purpose signal lines, where the fourth two-purpose signal line is not electrically connected to the signal terminals of any temperature detection units. The multiple bidirectional switching switches 55H are respectively the first bidirectional switching switch 55-1H, the second bidirectional switching switch 55-2H, the third bidirectional switching switch 55-3H, and the fourth bidirectional switching switch 55-4H. The first bidirectional switching switch 55-1H, the second bidirectional switching switch 55-2H, and the third bidirectional switching switch 55-3H respectively control the switching of the corresponding one two-purpose signal line 19H in the multi-purpose signal line 19H of the same electrode sheet 13H between transmitting an alternating current signal and transmitting a temperature detection signal. The fourth bidirectional switching switch 55-4H is not connected to any two-purpose signal lines, and the fourth bidirectional switching switch 55-4H is not used for signal control.

[0402] Among them, the other content in this embodiment is similar to that in the above Embodiment 8, and will not be elaborated here.

[0403] Embodiment 10:

[0404] The main concept of the above tumor electrotherapy system 100 is that an alternating power line 57 is provided in both the adapter 20 and the electric field generator 30 to control the synchronous change of the alternating electric signals of all the electrode units 33 on one electrode patch 13, such as the simultaneous increase or decrease of voltage or current. Different alternating electric signals, such as voltages or currents of different magnitudes, cannot be simultaneously applied to the electrode units 33 in different row groups. Refer to Figures 27 to 31 , another tumor electrotherapy system 100' is described below. Its main concept is the same as that of the above tumor electrotherapy system 100, except that: for each row group of electrode units 33' on the corresponding electrode patch 13' in the adapter 20' and the electric field generator 30' of this tumor electrotherapy system 100', a corresponding alternating power line 57' is provided, so that different alternating electric signals, such as voltages or currents of different magnitudes, can be simultaneously applied to different row groups of electrode units 33'.

[0405] Figure 28 FIG. is a schematic circuit connection diagram of one electrode patch 13' of another tumor electrotherapy system 100' according to an embodiment of the present application with the adapter 20' and the electric field generator 30'. Figure 29 FIG. is a schematic diagram of another electrode unit 33'. This tumor electrotherapy system 100' includes: at least a pair of electrode patches 13', an adapter 20' connected to the electrode patch 13', and an electric field generator 30' connected to the adapter 20'.

[0406] Among them, the specific structure of the electrode patch 13' is the same as that of the above electrode patch 13, and the structure of the temperature detection unit 35' is also the same as that of the above temperature detection unit 35, which will not be elaborated here.

[0407] The specific structure of the adapter 20' is similar to that of the above adapter 20, except that: refer to Figure 28 and Figure 30 , 4 alternating power lines 57' are provided in the adapter 20' corresponding to one electrode patch 13'. The 4 alternating power lines 57' are arranged in one-to-one correspondence with the 4 row groups of electrode units 33' of one electrode patch 13'. A corresponding bidirectional switch 55' and a grounding switch 54' are provided for each electrode patch 13'. Both ends of the bidirectional switch 55' are electrically connected to a separate alternating power line 57', so that the tumor electrotherapy system 100' can simultaneously apply different alternating electric signals, such as different voltages or currents, to different row groups of electrode units 33' in each electrode patch 13' as needed.

[0408] The specific structure of the electric field generator 30' is similar to that of the above electric field generator 30, except that: refer to Figure 28 and Figure 31, for each alternating power supply line 57' between the AC signal generator 39' and the alternating power supply line 57' connected to the adapter 20', a power supply switch 40' is provided to independently control the on / off of the alternating current signal of each row group electrode unit 33' of each electrode plate 13'.

[0409] Specifically, referring to Figure 28 and Figure 30 as shown, the adapter 20' includes: a first controller 51', multiple groups of ADC units 52' connected to the first controller 51', multiple groups of voltage dividing resistors 53' and multiple groups of control switches 54' corresponding to the multiple groups of ADC units 52' one by one, multiple groups of bidirectional switching switches 55' connected to the multiple groups of ADC units 52' one by one, a first communication unit 56', multiple alternating power supply lines 57' connected to the multiple groups of bidirectional switching switches 55' one by one, and a first power supply module 58' connected to the first communication unit 56', the first controller 51' and the multiple groups of ADC units 52' at the same time. The first power supply module 58' provides a DC power supply VCC for each electronic component of the adapter 20'. The adapter 20' also includes multiple circuit lines (not labeled). The multiple circuit lines (not labeled) are respectively electrically connected to multiple ground lines 18' and multiple dual-purpose signal lines 19' in the substrate 31' of the corresponding electrode plate 13' through the first cable 15' of the corresponding electrode plate 13'. The multiple circuit lines (not labeled) include multiple alternating power supply lines 57' that respectively transmit alternating current signals to the corresponding electrode plates 13' and are respectively electrically connected to different dual-purpose signal lines 19' in the substrate 31' of the corresponding electrode plates 13', multiple circuit lines (not labeled) that are respectively electrically connected to the multiple dual-purpose signal lines 19' in the substrate 31' of the corresponding electrode plates 13' one by one and are used to supply power to each temperature detection unit 35' of the corresponding electrode plate 13' or transmit the temperature detection signal of the corresponding electrode plate 13', and multiple circuit lines (not labeled) that are respectively electrically connected to the multiple ground lines 18' in the substrate 31' of the corresponding electrode plates 13' one by one. The number L of circuit lines of the adapter 20' electrically connected to an electrode plate 13' is equal to the sum of the number of rows and columns of the electrode unit 33' of the electrode plate 13' plus one; the number H of circuits of the adapter 20' electrically connected to X electrode plates 13' is X times the number of circuit lines of the adapter 20' electrically connected to a single electrode plate 13', that is, H = XL = X*(M + N + 1). The number of groups of the control switches 54' and the number of groups of the bidirectional switching switches 55' are both related to the number of electrode plates 13'. The number of groups of the control switches 54' is the same as the number of groups of the bidirectional switching switches 55', and is not less than the number of electrode plates 13'. Optionally, the number of groups of the control switches 54' and the number of groups of the bidirectional switching switches 55' are both the same as the number of electrode plates 13'.

[0410] For example, each set of control switches 54' is provided with a plurality of control switches 54'. The plurality of control switches 54' are respectively connected into the adapter 20' and are respectively electrically connected to circuit lines (not labeled) corresponding to the multiple ground wires 18' of a corresponding electrode plate 13', and are configured to control the conduction or disconnection of the multiple ground wires 18'. The circuit lines (not labeled) of the multiple ground wires 18' that are respectively and electrically connected to the electrode plate 13' are grounded at one end close to the control switch 54'. The number of control switches 54' in each set of control switches 54' is related to the number of ground wires 18' of the substrate 31' of the corresponding electrode plate 13'. In this embodiment, the two are equal. As Figure 28As shown, in this embodiment, the multiple control switches 54' in each group of control switches 54' are respectively the first control switch 54-1', the second control switch 54-2', the third control switch 54-3', the fourth control switch 54-4' and the fifth control switch 54-5'. Multiple control switches 54' in the same group respectively control the closing or opening of the corresponding ground wires 18' of the same electrode plate 13'. The first control switch 54-1' is used to control the closing or opening of the first ground wire 18-1' of the corresponding electrode plate 13', and then can cooperate with the corresponding group of bidirectional switching switches 55' and the rectifier switching unit 16' to control the energization and power-off of the respective temperature detection units 35' corresponding to the four electrode units 33' in the first column group of the electrode plate 13', namely the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11' and the electrode unit 33-16'; the second control switch 54-2' is used to control the closing or opening of the second ground wire 18-2' of the electrode plate 13', and then can cooperate with the corresponding group of bidirectional switching switches 55' and the rectifier switching unit 16' to control the energization and power-off of the temperature detection units 35' corresponding to multiple electrode units (the multiple electrode units can be respectively: the electrode unit 33-1' and the electrode unit 33-2', the electrode unit 33-6' and the electrode unit 33-7', the electrode unit 33-11' and the electrode unit 33-12', the electrode unit 33-16' and the electrode unit 33-17') in the first column group and the second column group of the electrode plate 13'; the third control switch 54-3' is used to control the closing or opening of the third ground wire 18-3' of the electrode plate 13', and then can cooperate with the corresponding group of bidirectional switching switches 55' and the rectifier switching unit 16' to control the energization and power-off of the respective temperature detection units 35' corresponding to multiple electrode units (the multiple electrode units can be respectively: the electrode unit 33-1' to the electrode unit 33-3', the electrode unit 33-6' to the electrode unit 33-8', the electrode unit 33-11' to the electrode unit 33-13', the electrode unit 33-16' to the electrode unit 33-18') in the first column group, the second column group and the third column group of the electrode plate 13'; the fourth control switch 54-4' and the fifth control switch 54-5' are the same by analogy and will not be elaborated here. The above control switches 54' can be mechanical switches, such as relays. The control switches 54' can also be electronic switches, and each control switch 54' can be opened and closed through an additional first controller 51'.

[0411] In this embodiment, multiple groups of control switches 54' are all electronic switches. The first controller 51' is communicatively connected to multiple groups of control switches 54' and is used to sequentially and cyclically control the opening and closing states of multiple control switches 54' in each group of control switches 54', thereby sequentially and individually conducting each of the multiple ground wires 18' of the corresponding electrode plate 13' and cooperating with the switching of the corresponding bidirectional switching switch 55' to collect the temperatures of the patient's body surface detected by all the temperature detection units 35' on the electrode plate 13'. The number of control switches 54' in each group is not less than the number of ground wires 18' of the substrate 31' of the corresponding electrode plate 13'. In this embodiment, the number of control switches 54' in each group is the same as the number of ground wires 18' of the corresponding electrode plate 13'.

[0412] Each group of bidirectional switching switches 55' is provided with multiple bidirectional switching switches 55'. The multiple bidirectional switching switches 55' in each group are respectively connected into the adapter 20' and are respectively electrically connected to circuit lines (not labeled) corresponding to the multiple multi-purpose signal lines 19' of a corresponding electrode plate 13'. The number of bidirectional switching switches 55' in each group of bidirectional switching switches 55' is related to the number of multi-purpose signal lines 19' of the substrate 31' of the corresponding electrode plate 13', and is greater than or equal to the number of multi-purpose signal lines 19' of the substrate 31' of the corresponding electrode plate 13'. In this embodiment, the two are equal. Each bidirectional switching switch 55' has two ends labeled 1 and 2. The 1 ends of the multiple bidirectional switching switches 55' in the same group are respectively electrically connected to the corresponding detection channels of the multiple detection channels of a corresponding group of ADC units 52' through temperature sampling points (not labeled). The 2 ends of each bidirectional switching switch 55' in the same group are electrically connected to different alternating power supply lines 57', and are configured to control the multi-purpose signal lines 19' to be connected to different alternating power supply lines 57' to transmit alternating current signals or to be connected to the corresponding detection channels of the corresponding group of ADC units 52' to receive the temperature detection signals output by the temperature detection units 35'.

[0413] As Figure 28As shown, taking the electrical connection between an electrode plate 13' and an adapter 20' as an example, in this embodiment with 20 electrode units 33', multiple two-way switching switches 55' in each group of two-way switching switches 55' are respectively a first two-way switching switch 55-1', a second two-way switching switch 55-2', a third two-way switching switch 55-3', and a fourth two-way switching switch 55-4'. Multiple two-way switching switches 55' in the same group respectively control the switching of the corresponding one of the multiplexed signal lines 19' of the same electrode plate 13' between transmitting an alternating current signal and transmitting a temperature detection signal. Specifically, the first two-way switching switch 55-1' is used to control the switching of the first multiplexed signal line 19-1' of the corresponding electrode plate 13' between transmitting the alternating current signal output by the alternating current power supply line 57-1' and transmitting the temperature detection signal, and further control the switching between the parallel conduction of the electrode units 33' of the electrode units 33-1' to 33-5' in the first row group of the electrode plate 13' and the conduction of the signal terminals 35-2' of the corresponding temperature detection units 35' of the electrode units 33-1' to 33-5' in the first row group. In cooperation with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5', the first row of electrode units 33-1' to 33-5' transmits a separate alternating current signal to the patient or enables the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35' of these electrode units 33' to be sampled and output to the corresponding ADC unit 52' respectively; the second two-way switching switch 55-2' is used to control the switching of the second multiplexed signal line 19-2' of the corresponding electrode plate 13' between transmitting the alternating current signal output by the alternating current power supply line 57-2' and transmitting the temperature detection signal, and further control the switching between the parallel conduction of the electrode units 33' of the electrode units 33-6' to 33-10' in the second row group of the electrode plate 13' and the conduction of the signal terminals 35-2' of the corresponding temperature detection units 35' of the electrode units 33-6' to 33-10' in the second row group. In cooperation with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5', the second row of electrode units 33-6' to 33-10' transmits a separate alternating current signal to the patient or enables the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35' of these electrode units 33' to be sampled and output to the corresponding ADC unit 52' respectively;The third bidirectional switch 55-3' is used to control the switching of the third dual-purpose signal line 19-3' of the corresponding electrode plate 13' between transmitting the alternating-current signal output by the alternating-current power line 57-3' and transmitting the temperature detection signal, thereby controlling the switching between the parallel conduction of each electrode unit 33' of the electrode units 33-11' to 33-15' in the third row group of the electrode plate 13' and the conduction of the signal terminal 35-2' of each corresponding temperature detection unit 35' of the electrode units 33-11' to 33-15' in the third row group, and cooperating with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5' to enable the third row of electrode units 33-11' to 33-15' to transmit a separate alternating-current signal to the patient or to sample and output the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35' of these electrode units 33' to the corresponding ADC unit 52'; the fourth bidirectional switch 55-4' is used to control the switching of the fourth dual-purpose signal line 19-4' of the corresponding electrode plate 13' between transmitting the alternating-current signal output by the alternating-current power line 57-4' and transmitting the temperature detection signal, thereby controlling the switching between the parallel conduction of each electrode unit 33' of the electrode units 33-16' to 33-20' in the fourth row group of the electrode plate 13' and the conduction of the signal terminal 35-2' of each corresponding temperature detection unit 35' of the electrode units 33-16' to 33-20' in the fourth row group, and cooperating with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5' to enable the fourth row of electrode units 33-16' to 33-20' to transmit a separate alternating-current signal to the patient or to sample and output the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the corresponding temperature detection units 35' of these electrode units 33' to the corresponding ADC unit 52'. The above bidirectional switch 55' can be a mechanical switch, such as a relay. The bidirectional switch 55' can also be an electronic switch, and each bidirectional switch 55' can be switched by an additional first controller 51'.

[0414] In this embodiment, multiple groups of bidirectional switches 55' are all electronic switches. The first controller 51' is communicatively connected to multiple groups of bidirectional switches 55' and is used to control multiple bidirectional switches 55' in each group of bidirectional switches 55' to switch between their terminal 1 and terminal 2, and cooperate with the closing or opening of the corresponding control switch 54' to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 35' on the electrode plate 13' or transmit an alternating-current signal to the patient.

[0415] In this embodiment, each group of ADC units 52' is respectively and electrically connected to one end of a plurality of two-way switches 55' in the corresponding group of two-way switching switches 55' through a multi-channel circuit line (not labeled) in the adapter 20', and is configured to receive the temperature detection signals transmitted by the multi-purpose signal lines 19' of the corresponding electrode plates 13', and convert the temperature detection signals from analog signals into digital temperature signals. Each group of ADC units 52' includes a plurality of detection channels A, B, C, and D, and each detection channel A, B, C, and D is used to connect to a corresponding one of the multi-purpose signal lines 19' in the multi-purpose signal line 19' through the corresponding two-way switch 55'. As Figure 28 shown, each group of ADC units 52' includes a total of 4 detection channels A, B, C, and D, namely the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. The first detection channel A is connected to the first multi-purpose signal line 19-1' through one end of the first two-way switch 55-1', the second detection channel B is connected to the second multi-purpose signal line 19-2' through one end of the second two-way switch 55-2', the third detection channel C is connected to the third multi-purpose signal line 19-3' through one end of the third two-way switch 55-3', and the fourth detection channel D is connected to the fourth multi-purpose signal line 19-4' through one end of the fourth two-way switch 55-4'. Each detection channel A, B, C, and D is used to receive the temperature detection signals collected by the corresponding temperature detection unit 35' of the electrode unit 33' connected to the corresponding multi-purpose signal line 19'. In addition, each of the detection channels A, B, C, and D is connected to a first power supply module 58' for providing a detection voltage to this detection channel A, B, C, and D through a corresponding voltage dividing resistor 53' in the adapter 20', and the first power supply module 58' provides direct current.

[0416] In this embodiment, the first communication unit 56' is configured to acquire a plurality of sets of digital temperature signals output by the ADC units 52' and send the digital temperature signals to the electric field generator 30'. The electric field generator 30' is further configured to control and adjust the voltage of the alternating electric signal provided to the plurality of electrode units 33' of the electrode plate 13' according to the received digital temperature signals. Exemplarily, when any one of the plurality of received digital temperature signals exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode plate 13' exceeds the preset threshold temperature (such as 41°C, 42°C, etc.). At this time, the voltage of the alternating electric signal output by the electric field generator 30' can be appropriately reduced or stopped to avoid excessive temperature of the electrode units 33' of the electrode plate 13' when applying the alternating electric signal, causing low-temperature burns to the patient's skin. The above preset threshold temperature and preset threshold can be determined according to the human safety threshold. The first communication unit 56' is controlled by the first controller 51' and serially transmits the digital temperature signals converted by the plurality of ADC units 52'. In this embodiment, the preset threshold temperature can be a value within 36°C - 45°C.

[0417] Reference Figure 28, in this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30' correspondingly, and is configured to supply power to the first controller 51', multiple groups of ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is connected between each electrode plate 13' and the adapter 20', and the first connector 60' is adapted to connect the corresponding electrode plate 13' to the adapter 20'. A second connector 70' is provided between the adapter 20'...

Claims

1. A method for detecting abnormality of an electrode sheet, characterized in that: Applicable to a tumor electric field therapy system, the tumor electric field therapy system comprises at least one pair of electrode sheets, each of the electrode sheets comprises a plurality of electrode units and a plurality of temperature detection units, each of the electrode units can apply an alternating electric signal, each of the temperature detection units is arranged corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are configured into at least two row groups and at least two column groups in terms of circuit connection, the temperature detection units in each row group are connected in series to form a temperature detection end, and the grounding end of each temperature detection unit in each column group is connected to a grounding pin through a control switch, and the method comprises: When the temperature detection end corresponding to the switching target row group is connected to the corresponding temperature sampling point, the control switches corresponding to the column group where each temperature detection unit in the target row group is located are controlled to be closed in sequence, so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature detection units in the target row group are sampled respectively based on the corresponding temperature sampling point; Determining the temperature of each electrode unit in the target row group based on the respectively sampled analog temperature signals; Whether the electrode sheet is abnormal is determined according to the temperature at each electrode unit.

2. The method according to claim 1, characterized in that Judging whether the electrode sheet is abnormal according to the temperature at each electrode unit includes: When it is determined based on the temperature at each electrode unit that any one of the electrode units in the corresponding electrode sheet is abnormal or fails, the electrode sheet is determined to be unqualified.

3. The method according to claim 1, characterized in that Judging whether the electrode sheet is abnormal according to the temperature at each electrode unit includes: In the case where the presence of abnormal or faulty electrode units in the corresponding electrode sheet is determined based on the temperature at each electrode unit, the number of the abnormal or faulty electrode units is determined; When the number of abnormal or faulty electrode units reaches a preset threshold, it is determined that the electrode sheet needs to be replaced.

4. The method according to claim 3, characterized in that When the number of abnormal or faulty electrode units reaches a preset threshold, the method further includes: Stop applying the alternating current signal to each electrode unit of the electrode sheet.

5. The method according to claim 1, characterized in that Judging whether the electrode sheet is abnormal according to the temperature at each electrode unit includes: comparing the temperature at each electrode unit in the corresponding electrode sheet with a preset temperature threshold; Whether the temperature of the electrode sheet is abnormal is determined based on the comparison result.

6. The method according to claim 5, characterized in that Judging whether the temperature of the electrode sheet is abnormal based on the comparison result includes: When the temperature at any one electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet is abnormal.

7. The method according to claim 5, characterized in that When the temperature at any one electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold, the method further includes: Determine the number of over-temperature areas; When the number of the over-temperature areas exceeds a preset number threshold, the application of the alternating current signal to each electrode unit of the electrode sheet is stopped.

8. The method according to any one of claims 1 to 7, characterized in that When the control switch corresponding to the column group where the first temperature detection unit connected to the temperature detection end in the target row group is located is closed, the analog temperature signal detected by the first temperature detection unit is sampled based on the corresponding temperature sampling point.

9. The method according to claim 8, characterized in that When the control switch corresponding to the column group where the second temperature detection unit adjacent to the first temperature detection unit in the target row group is located is closed, the analog temperature signal detected by the combination of the first temperature detection unit and the second temperature detection unit is sampled based on the corresponding temperature sampling point; When the control switch corresponding to the column group where the third temperature detection unit adjacent to the second temperature detection unit in the target row group is located is closed, the analog temperature signal detected by the combination of the first temperature detection unit, the second temperature detection unit and the third temperature detection unit is sampled based on the corresponding temperature sampling point; By analogy, when the control switch corresponding to the column group where the last temperature detection unit in the target row group is located is closed, the analog temperature signals detected by the combination of temperature detection units in the target row group are sampled based on the corresponding temperature sampling points.

10. The method according to claim 9, characterized in that Determining the temperature of each electrode unit in the target row group based on the respectively sampled analog temperature signals includes: Determining the temperature at a first electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit; Determine the temperature at the second electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit and the analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit; Determine the temperature at the third electrode unit in the target row group based on the sampled analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit, and the analog temperature signal corresponding to the combination of the first temperature detection unit, the second temperature detection unit, and the third temperature detection unit; By analogy, the temperatures at the fourth electrode unit to the last electrode unit in the target row group are determined.

11. The method according to claim 8, characterized in that The temperature detection end corresponding to each row group is connected to the first switching end of the corresponding rectifier switching unit, the second switching end of the rectifier switching unit corresponding to each row group is respectively connected to each electrode unit in the corresponding row group, the fixed end of the rectifier switching unit corresponding to each row group is connected to the fixed end of the corresponding bidirectional switch through a dual-purpose signal line, the first end of the bidirectional switch corresponding to each rectifier switching unit is the temperature sampling point of the corresponding row group, and the second end of the bidirectional switch corresponding to each rectifier switching unit is simultaneously connected to the alternating power line, wherein the temperature detection end corresponding to the switching target row group is connected to the corresponding temperature sampling point, including: The rectifying switching unit corresponding to the target row group is controlled to be linked with the corresponding bidirectional switch, so that the temperature detection end corresponding to the target row group is connected to the corresponding temperature sampling point.

12. A computer-readable storage medium, characterized in that: A computer program is stored thereon, and when the computer program is executed by a processor, the electrode sheet abnormality detection method according to any one of claims 1-11 is implemented.

13. A tumor electric field treatment system, comprising a memory and a controller, characterized in that: The memory stores a computer program, which, when executed by the controller, implements the electrode sheet abnormality detection method according to any one of claims 1-11.

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