Micro-fluidic chip clamping device

Abstract

The invention relates to the technical field of micro-fluidic chips, and particularly discloses a micro-fluidic chip clamping device which comprises a clamping seat, a clamping device and a clamping device, a plurality of clamping grooves are formed in the top end of the clamping seat, adjusting grooves are formed in the middles of the inner walls of the clamping grooves, a driving mechanism is jointly installed among the adjusting grooves, a plurality of front clamping mechanisms are installed on the front portion of the outer surface of the driving mechanism, and a plurality of rear clamping mechanisms are installed on the rear portion of the outer surface of the driving mechanism. A shaking mechanism is mounted at the bottom end of the clamping seat; according to the invention, the two clamping plates are used for clamping a chip from the front and back, and the driving motor is used for driving the positive and negative lead screws to rotate, so that the two pressing mechanisms are used for clamping the chip from the left, right, up and down directions, the chip is stably fixed in all directions, and the chip is effectively prevented from moving or deforming in the operation process; therefore, the accuracy and the stability of the experiment are ensured, and the device has wide applicability.

Description

Technical Field

[0001] The present invention belongs to the technical field of microfluidic chips, and particularly relates to a clamping device for a microfluidic chip. Background Art

[0002] Microfluidic chip technology is a science and technology for precisely controlling and operating trace fluids within the micron scale range. A microfluidic chip, as the main implementation platform of this technology, integrates basic biochemical operation units such as sample preparation, reaction, separation, and detection, and has advantages such as miniaturization, integration, high throughput, and low cost of equipment. During the application process of the microfluidic chip, the clamping device plays a crucial role. It can not only ensure the stable fixation of the microfluidic chip during operation but also achieve an effective interface connection with macroscopic equipment to ensure the smooth flow of fluid in the microchannels.

[0003] In the Chinese patent with the publication number CN211073278U, a soft fixture for a microfluidic chip is mentioned. Slowly turn the screw towards the adjusting component, so that the pressing plate slowly presses the adjusting component. The pressed adjusting component will slowly push the left cylinder or the right cylinder towards the center. After adjusting to firmly clamp the chip, the nut can be screwed onto the outside of the screw and fitted against the outer wall of the vertical plate. This not only facilitates the user to quickly adjust the clamping degree of the fixture but also has a simple and convenient operation, greatly improving the convenience of the user to adjust the fixture. However, this clamping device has limitations in use and can only perform clamping in a single direction, which makes the microfluidic chip prone to movement or deformation during operation, thereby affecting the accuracy and stability of the experiment. Summary of the Invention

[0004] The purpose of the present invention is to provide a clamping device for a microfluidic chip, which can clamp the microfluidic chip in multiple directions to solve the problem that the chip is prone to movement or deformation during the experiment.

[0005] To achieve the above purpose, the present invention provides the following technical solutions:

[0006] A clamping device for a microfluidic chip, comprising:

[0007] A clamping seat;

[0008] A plurality of clamping grooves are opened at the top end of the clamping seat. Adjusting grooves are opened in the middle of the inner walls of the plurality of clamping grooves. A driving mechanism is commonly installed among the plurality of adjusting grooves. A plurality of front clamping mechanisms are installed at the front part of the outer surface of the driving mechanism, and a plurality of rear clamping mechanisms are installed at the rear part of the outer surface of the driving mechanism. A shaking mechanism is installed at the bottom end of the clamping seat;

[0009] The post-clamping mechanism includes a clamping plate, a driving motor, a limiting groove, a positive and negative screw rod, and a pressing mechanism. The clamping plate is installed on the outer surface of the driving mechanism. The driving motor is installed at one end of the clamping plate. The limiting groove is opened on the outer wall of the clamping plate. The positive and negative screw rod is installed between the inner walls on both sides of the limiting groove through bearings. There are two pressing mechanisms, and the two pressing mechanisms are respectively installed on both sides of the outer surface of the positive and negative screw rod.

[0010] Preferably, a chip body is placed inside each of the plurality of clamping grooves. A protective cover is installed on the outer wall of the clamping seat. The bottom end of the shaking mechanism is installed with a mounting base. Guide grooves are opened on both sides of the top end of the mounting base. Guide frames are slidably installed inside the two guide grooves, and the top ends of the two guide frames are installed at the bottom end of the clamping seat. Two moving wheels are installed on the top inner walls of the two guide frames. Two locking bolts are installed at both ends of the mounting base.

[0011] Preferably, an avoidance groove is opened in the middle of the top end of the mounting base. The guide frame is arranged in an L-shaped structure, and the bottom end of the moving wheel contacts the top end of the mounting base.

[0012] Preferably, the pressing mechanism includes a clamping frame, a limiting block, an electric push rod, and a pressing plate. The limiting block is installed on the outer wall of the clamping frame and on the outer surface of the positive and negative screw rod. The electric push rod is installed at the top end of the clamping frame. The pressing plate is installed at the bottom end of the electric push rod.

[0013] Preferably, the clamping frame is arranged in an L-shaped structure. The limiting block and the clamping plate are both arranged in a convex structure. The structure of the post-clamping mechanism is the same as that of the front-clamping mechanism.

[0014] Preferably, the driving mechanism includes a positive and negative screw, a synchronous rod, a pulley, a synchronous belt, and a driver. There are multiple positive and negative screws, synchronous rods, pulleys, and synchronous belts. The multiple positive and negative screws are respectively installed between the inner walls on both sides of multiple adjustment grooves through bearings. The multiple synchronous rods are respectively installed at one end of the multiple positive and negative screws. The multiple pulleys are respectively installed at the other end of the multiple synchronous rods. The multiple synchronous belts are respectively sleeved between the outer surfaces of adjacent two pulleys. The driver is installed at the other end of the middlemost positive and negative screw.

[0015] Preferably, the pulley and the synchronous belt are both located inside the protective cover, and the outer surface of the pulley is designed with a double groove.

[0016] Preferably, the shaking mechanism includes a fixed box, a shaking frame, an adjustment opening, and adjustment teeth. The fixed box is installed at the top end of the installation base. The shaking frame is inserted and installed between the inner walls on both sides of the fixed box, and the top end of the shaking frame is installed at the bottom end of the clamping seat. The adjustment opening is formed at the bottom end of the shaking frame. A plurality of adjustment teeth are provided, and the plurality of adjustment teeth are respectively installed on the inner walls on both sides of the adjustment opening.

[0017] Preferably, a motor is installed in the middle of the bottom end of the fixed box. The output end of the motor is installed with a driving shaft, and the driving shaft is installed between the top inner wall and the bottom inner wall of the fixed box through a bearing. A reciprocating gear is installed on the outer surface of the driving shaft.

[0018] Preferably, the reciprocating gear meshes with the adjustment teeth, and the number of teeth on the reciprocating gear is the same as the number of adjustment teeth on the inner walls on both sides of the adjustment opening.

[0019] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0020] (1) In the present invention, a front clamping mechanism and a rear clamping mechanism are arranged on the outer surface of the driving mechanism. The chip is clamped from the front and back by two clamping plates. The driving motor drives the forward and reverse screw rod to rotate, so that the two pressing mechanisms clamp the chip from multiple directions of left and right and up and down, realizing the stable fixation of the chip in all directions. This effectively avoids the movement or deformation of the chip during the operation process, thereby ensuring the accuracy and stability of the experiment and making the device have wide applicability.

[0021] (2) In the present invention, a driving mechanism is arranged inside the adjustment groove. Through the drive of the driver and the synchronous transmission between the pulley and the synchronous belt, multiple forward and reverse screw rods can be driven to rotate synchronously, and then drive multiple front clamping mechanisms and rear clamping mechanisms to move towards the middle at the same time, so that the clamping device can clamp multiple microfluidic chips at the same time, meeting the batch processing requirements of microfluidic chips and greatly improving the experimental efficiency.

[0022] (3) In the present invention, a shaking mechanism is arranged at the bottom end of the clamping seat. The motor drives the reciprocating gear to rotate, and through the meshing transmission between the reciprocating gear and the adjustment teeth, the shaking frame drives the clamping seat and the microfluidic chip to shake back and forth. In this way, after the detection liquid enters the microfluidic chip body, it can be better drained to each part of the chip that needs to be detected. Description of the Drawings

[0023] Figure 1 is a three-dimensional view of the present invention;

[0024] Figure 2 is the present invention Figure 1 an enlarged view of A in;

[0025] Figure 3Isometric view of the post-clamping mechanism of the present invention;

[0026] Figure 4 Isometric view of the pressing mechanism of the present invention;

[0027] Figure 5 Isometric view of the driving mechanism of the present invention;

[0028] Figure 6 Isometric view of the mounting base of the present invention;

[0029] Figure 7 Cross-sectional view of the shaking mechanism of the present invention;

[0030] Figure 8 For the present invention Figure 7 Enlarged view of B in;

[0031] In the figure: 1, clamping seat; 2, clamping groove; 3, adjustment groove; 4, driving mechanism; 5, front clamping mechanism; 6, post clamping mechanism; 7, shaking mechanism; 8, chip body; 9, protective cover; 10, mounting base; 11, guide groove; 12, guide frame; 13, moving wheel; 14, locking bolt;

[0032] 41, positive and negative screw rod; 42, synchronous rod; 43, pulley; 44, synchronous belt; 45, driver;

[0033] 61, clamping plate; 62, driving motor; 63, limit groove; 64, positive and negative screw rod; 65, pressing mechanism;

[0034] 651, clamping frame; 652, limit block; 653, electric push rod; 654, pressing plate;

[0035] 71, fixed box; 72, shaking frame; 73, adjustment port; 74, adjustment tooth block; 75, motor; 76, drive shaft; 77, reciprocating gear. Detailed implementation manners

[0036] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0037] Embodiment 1:

[0038] Please refer to Figures 1 to 8 As shown, a microfluidic chip clamping device includes:

[0039] Clamping seat 1;

[0040] A plurality of clamping grooves 2 are formed at the top end of the clamping seat 1. Adjusting grooves 3 are formed in the middle of the inner walls of the plurality of clamping grooves 2. A driving mechanism 4 is commonly installed among the plurality of adjusting grooves 3. A plurality of front clamping mechanisms 5 are installed on the front part of the outer surface of the driving mechanism 4. A plurality of rear clamping mechanisms 6 are installed on the rear part of the outer surface of the driving mechanism 4. A shaking mechanism 7 is installed at the bottom end of the clamping seat 1;

[0041] The rear clamping mechanism 6 includes a clamping plate 61, a driving motor 62, a limiting groove 63, a positive and negative lead screw 64 and a pressing mechanism 65. The clamping plate 61 is installed on the outer surface of the driving mechanism 4. The driving motor 62 is installed at one end of the clamping plate 61. The limiting groove 63 is formed in the outer wall of the clamping plate 61. The positive and negative lead screw 64 is installed between the inner walls on both sides of the limiting groove 63 through bearings. There are two pressing mechanisms 65, and the two pressing mechanisms 65 are respectively installed on both sides of the outer surface of the positive and negative lead screw 64.

[0042] As Figures 1 to 4 can be seen, chip bodies 8 are placed inside the plurality of clamping grooves 2. A protective cover 9 is installed on the outer wall of the clamping seat 1. An installation base 10 is installed at the bottom end of the shaking mechanism 7. Guide grooves 11 are formed on both sides of the top end of the installation base 10. Guide frames 12 are slidably installed inside the two guide grooves 11, and the top ends of the two guide frames 12 are installed at the bottom end of the clamping seat 1. Two moving wheels 13 are installed on the top inner walls of the two guide frames 12. Two locking bolts 14 are installed at both ends of the installation base 10;

[0043] The pressing mechanism 65 includes a clamping frame 651, a limiting block 652, an electric push rod 653 and a pressing plate 654. The limiting block 652 is installed on the outer wall of the clamping frame 651 and is installed on the outer surface of the positive and negative lead screw 64. The electric push rod 653 is installed at the top end of the clamping frame 651. The pressing plate 654 is installed at the bottom end of the electric push rod 653.

[0044] As can be seen from the above, by controlling the driving mechanism 4 to start through the controller, the front clamping mechanism 5 and the rear clamping mechanism 6 can be driven to move towards the middle simultaneously, and the adjustment groove 3 is used to guide and limit the clamping plate 61, so that the two clamping plates 61 stably clamp the chip body 8 from the front and rear directions. Then, the controller starts the driving motor 62 and the electric push rod 653 in sequence, so that the driving motor 62 drives the forward and reverse lead screw 64 to rotate, and the two limit blocks 652 on it move towards the middle. The limit groove 63 is used to guide and limit the limit blocks 652, and the two clamping frames 651 stably clamp the chip body 8 from the left and right directions. Subsequently, the electric push rod 653 extends to push the pressing plate 654 to move downward, which can cooperate with the clamping groove 2 to stably clamp the chip body 8 from the up and down directions. In this way, the chip body 8 is stably clamped in multiple directions of front and rear, left and right, and up and down, achieving stable fixation in all directions. This effectively avoids the movement or deformation of the chip body 8 during the operation process, ensures its normal operation during the experiment, reduces the risk of experimental failure and repeated operations. At the same time, this stable clamping also improves the accuracy of the experiment and makes the clamping device have wide applicability.

[0045] Specifically, referring to Figures 1 to 4 As shown, an avoidance groove is provided in the middle of the top end of the installation base 10. The guiding frame 12 is arranged in an L-shaped structure, and the bottom end of the moving wheel 13 is in contact with the top end of the installation base 10; the clamping frame 651 is arranged in an L-shaped structure, the limit block 652 and the clamping plate 61 are both arranged in a convex structure, and the structure of the rear clamping mechanism 6 is the same as that of the front clamping mechanism 5.

[0046] As can be seen from the above, the avoidance groove provides installation space for the motor 75. The guiding frame 12 in an L-shaped structure is used to provide stable support and guiding functions, and can also help the moving wheel 13 maintain a specific movement direction to ensure that the moving wheel 13 can move smoothly on the installation base 10; the clamping frame 651 in an L-shaped structure can provide an installation position for the electric push rod 653 and is also convenient for clamping the chip body 8. The convex-shaped limit block 652 is convenient for sliding and limiting in the limit groove 63, and the convex-shaped clamping plate 61 is convenient for sliding and limiting in the adjustment groove 3, so that the functions of the rear clamping mechanism 6 and the front clamping mechanism 5 are the same.

[0047] Embodiment 2:

[0048] Referring to Figure 5As shown in the figure, the driving mechanism 4 includes a forward and reverse screw 41, a synchronous rod 42, a pulley 43, a synchronous belt 44, and a driver 45. There are multiple forward and reverse screws 41, synchronous rods 42, pulleys 43, and synchronous belts 44. Multiple forward and reverse screws 41 are respectively installed between the inner walls on both sides of multiple adjustment slots 3 through bearings. Multiple synchronous rods 42 are respectively installed at one end of multiple forward and reverse screws 41. Multiple pulleys 43 are respectively installed at the other end of multiple synchronous rods 42. Multiple synchronous belts 44 are respectively sleeved and installed between the outer surfaces of adjacent two pulleys 43. The driver 45 is installed at the other end of the middlemost forward and reverse screw 41.

[0049] As can be seen from the above, when it is necessary to clamp the chip body 8, first, place multiple chip bodies 8 into multiple clamping slots 2 respectively. Then, control the driver 45 to start through the controller, so that the middlemost forward and reverse screw 41 drives the corresponding synchronous rod 42 to rotate. Next, through the synchronous transmission between the pulley 43 and the synchronous belt 44, drive multiple forward and reverse screws 41 to rotate synchronously. Furthermore, drive multiple front clamping mechanisms 5 and multiple rear clamping mechanisms 6 to move towards the middle simultaneously, so that the clamping device can clamp multiple chip bodies 8 at the same time, realizing the synchronous clamping and loosening of multiple chip bodies 8. This method meets the batch processing requirements of microfluidic chips, greatly improves the experimental efficiency, reduces the experimental cost, simplifies the experimental operation steps at the same time, and reduces the skill requirements for operators.

[0050] Preferably, referring to Figure 5 As shown in the figure, both the pulley 43 and the synchronous belt 44 are located inside the protective cover 9, and the outer surface of the pulley 43 is designed with double grooves.

[0051] As can be seen from the above, the protective cover 9 protects the pulley 43 and the synchronous belt 44 from interference and damage from the external environment, improving the safety and reliability of the equipment. The double grooves on the pulley 43 can install two synchronous belts 44 at the same time, realizing bidirectional synchronous transmission.

[0052] Embodiment 3:

[0053] Referring to Figures 6 to 8 As shown in the figure, the shaking mechanism 7 includes a fixed box 71, a shaking frame 72, an adjustment port 73, and adjustment teeth 74. The fixed box 71 is installed at the top of the installation base 10. The shaking frame 72 is inserted and installed between the inner walls on both sides of the fixed box 71, and the top of the shaking frame 72 is installed at the bottom of the clamping seat 1. The adjustment port 73 is opened at the bottom of the shaking frame 72. There are multiple adjustment teeth 74, and multiple adjustment teeth 74 are respectively installed on the inner walls on both sides of the adjustment port 73;

[0054] A motor 75 is installed in the middle of the bottom end of the fixed box 71. The output end of the motor 75 is installed with a drive shaft 76, and the drive shaft 76 is installed between the top inner wall and the bottom inner wall of the fixed box 71 through bearings. A reciprocating gear 77 is installed on the outer surface of the drive shaft 76.

[0055] As can be seen from the above, after the chip body 8 is clamped, the locking bolt 14 can be rotated to cancel the locking of the guide frame 12, and then the motor 75 is controlled by the controller to start, so that the drive shaft 76 drives the reciprocating gear 77 to rotate. At this time, through the meshing transmission between the reciprocating gear 77 and the multiple adjusting teeth 74 on the adjusting port 73, the shaking frame 72 drives the clamping seat 1 to shake back and forth, and is slidably limited through the guide frame 12 in the guide groove 11, and cooperates with the moving wheels 13 to move and support on the installation base 10, so as to drive the chip body 8 to shake back and forth stably. In this way, when the detection liquid enters the inside of the chip body 8, the detection liquid can be better drained to each part of the chip body 8 that needs to be detected, realizing the uniform distribution and full contact of the detection liquid in the chip body 8, and improving the accuracy and efficiency of detection.

[0056] Preferably, as Figures 6 to 8 shown, the reciprocating gear 77 meshes with the adjusting teeth 74, and the number of teeth on the reciprocating gear 77 is the same as the number of adjusting teeth 74 on both inner walls of the adjusting port 73.

[0057] As can be seen from the above, the power is transmitted through the meshing of the teeth, realizing the reciprocating motion function of the shaking frame 72, and then driving the clamped chip body 8 to shake back and forth, ensuring the smooth and stable meshing between the reciprocating gear 77 and the adjusting teeth 74, and realizing the precise transmission and adjustment functions.

[0058] Application example:

[0059] The clamping device of the microfluidic chip designed in this way is widely used in biological laboratories, chemical analysis rooms, medical testing institutions, and R & D and production environments related to microfluidic technology. In biological laboratories, the device can clamp multiple microfluidic chips at the same time for the perfusion of cell culture medium and drug screening experiments; in chemical analysis rooms, it is used to clamp microfluidic chips containing different chemical reagents for the observation and analysis of chemical reactions; in medical testing institutions, the device clamps microfluidic chips containing patient samples for the detection and analysis of disease markers; in R & D and production environments, it is used in stages such as R & D testing and mass production of microfluidic chips;

[0060] This clamping device is mainly designed based on the principles of mechanical clamping and liquid flow. The driving mechanism 4 drives multiple front clamping mechanisms 5 and rear clamping mechanisms 6 on it to move towards the middle simultaneously, realizing the simultaneous clamping of multiple chip bodies 8, meeting the requirements of batch processing. By setting the front clamping mechanism 5 and the rear clamping mechanism 6, the chip body 8 can be clamped jointly from multiple directions, including front and back, left and right, up and down, ensuring its stable fixation in multiple directions, thereby guaranteeing the accuracy and stability of the experiment. In addition, the design of the shaking mechanism 7 enables the chip body 8 to shake back and forth, promoting the uniform distribution of the detection liquid in the chip body 8.

[0061] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A microfluidic chip clamping device, characterized in that: include: Clamping seat (1); The top of the clamping seat (1) is provided with a plurality of clamping grooves (2), the middle of the inner walls of the plurality of clamping grooves (2) are provided with adjustment grooves (3), a driving mechanism (4) is installed between the plurality of adjustment grooves (3), a plurality of front clamping mechanisms (5) are installed on the front of the outer surface of the driving mechanism (4), a plurality of rear clamping mechanisms (6) are installed on the rear of the outer surface of the driving mechanism (4), and a shaking mechanism (7) is installed on the bottom end of the clamping seat (1); The rear clamping mechanism (6) comprises a clamping plate (61), a driving motor (62), a limiting groove (63), a forward and reverse screw rod (64) and a clamping mechanism (65); the clamping plate (61) is mounted on the outer surface of the driving mechanism (4); the driving motor (62) is mounted at one end of the clamping plate (61); the limiting groove (63) is provided on the outer wall of the clamping plate (61); the forward and reverse screw rod (64) is mounted between the inner walls on both sides of the limiting groove (63) through bearings; and two clamping mechanisms (65) are provided, and the two clamping mechanisms (65) are respectively mounted on both sides of the outer surface of the forward and reverse screw rod (64).

2. A microfluidic chip clamping device according to claim 1, characterized in that: A chip body (8) is placed inside each of the plurality of clamping grooves (2), a protective cover (9) is installed on the outer wall of the clamping seat (1), a mounting base (10) is installed at the bottom end of the shaking mechanism (7), guide grooves (11) are provided on both sides of the top end of the mounting base (10), guide frames (12) are slidably installed inside the two guide grooves (11), and the top ends of the two guide frames (12) are installed at the bottom end of the clamping seat (1), two moving wheels (13) are installed on the top inner walls of the two guide frames (12), and two locking bolts (14) are installed at both ends of the mounting base (10).

3. A microfluidic chip clamping device according to claim 2, characterized in that: An avoidance groove is provided in the middle of the top of the installation base (10), the guide frame (12) is arranged as an L-shaped structure, and the bottom end of the moving wheel (13) contacts the top of the installation base (10).

4. The microfluidic chip clamping device according to claim 1, characterized in that: The clamping mechanism (65) comprises a clamping frame (651), a limit block (652), an electric push rod (653) and a clamping plate (654); the limit block (652) is mounted on the outer wall of the clamping frame (651), and the limit block (652) is mounted on the outer surface of the forward and reverse screw rods (64); the electric push rod (653) is mounted on the top end of the clamping frame (651), and the clamping plate (654) is mounted on the bottom end of the electric push rod (653).

5. A microfluidic chip clamping device according to claim 4, characterized in that: The clamping frame (651) is configured as an L-shaped structure, the limit block (652) and the clamping plate (61) are both configured as convex structures, and the structure of the rear clamping mechanism (6) is consistent with that of the front clamping mechanism (5).

6. The microfluidic chip clamping device according to claim 1, characterized in that: The driving mechanism (4) comprises a forward and reverse screw rod (41), a synchronous rod (42), a pulley (43), a synchronous belt (44) and a driver (45). The forward and reverse screw rod (41), the synchronous rod (42), the pulley (43) and the synchronous belt (44) are provided in plurality. The plurality of forward and reverse screw rods (41) are respectively installed between the inner walls on both sides of the plurality of adjustment grooves (3) through bearings. The plurality of synchronous rods (42) are respectively installed at one end of the plurality of forward and reverse screw rods (41). The plurality of pulleys (43) are respectively installed at the other end of the plurality of synchronous rods (42). The plurality of synchronous belts (44) are respectively sleeved and installed between the outer surfaces of two adjacent pulleys (43). The driver (45) is installed at the other end of the middle forward and reverse screw rod (41).

7. A microfluidic chip clamping device according to claim 6, characterized in that: The belt pulley (43) and the synchronous belt (44) are both located inside the protective cover (9), and the outer surface of the belt pulley (43) is designed with double grooves.

8. The microfluidic chip clamping device according to claim 1, characterized in that: The rocking mechanism (7) comprises a fixed box (71), a rocking frame (72), an adjustment port (73) and an adjustment tooth block (74); the fixed box (71) is mounted on the top of the mounting base (10); the rocking frame (72) is inserted between the inner walls on both sides of the fixed box (71); and the top of the rocking frame (72) is mounted on the bottom end of the clamping seat (1); the adjustment port (73) is opened at the bottom end of the rocking frame (72); a plurality of adjustment tooth blocks (74) are provided, and the plurality of adjustment tooth blocks (74) are respectively mounted on the inner walls on both sides of the adjustment port (73).

9. A microfluidic chip clamping device according to claim 8, characterized in that: A motor (75) is installed in the middle of the bottom end of the fixed box (71), a driving shaft (76) is installed at the output end of the motor (75), and the driving shaft (76) is installed between the top inner wall and the bottom inner wall of the fixed box (71) through a bearing, and a reciprocating gear (77) is installed on the outer surface of the driving shaft (76).

10. The microfluidic chip clamping device according to claim 9, characterized in that: The reciprocating gear (77) is meshed with the adjusting tooth blocks (74), and the number of tooth blocks on the reciprocating gear (77) is consistent with the number of adjusting tooth blocks (74) on the inner walls on both sides of the adjusting opening (73).

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