Optical detection device, control method thereof and sample analyzer

Abstract

The invention discloses an optical detection device, a control method thereof and a sample analyzer. In the optical detection device, a sealing cavity is formed in a shell; the optical assembly is arranged in the sealing cavity and is used for performing optical detection on the sample; the temperature sensor is arranged on the shell and used for sensing the temperature in the shell or the sealing cavity; the temperature adjusting mechanism is arranged on the shell and used for heating and refrigerating the shell or the sealing cavity. The control unit is connected with the temperature sensor and the temperature adjusting mechanism and used for obtaining the actual temperature in the shell or the sealing cavity through the temperature sensor. And when it is confirmed that the actual temperature is not within the range of the target temperature, the temperature adjusting mechanism is controlled to heat / refrigerate the shell or the sealing cavity, so that the temperature in the shell or the sealing cavity is within the range of the target temperature. According to the optical detection device, the temperature of the optical assembly in the optical detection device can be kept within a constant range, and the stability of the performance of the optical assembly is improved.

Description

Technical Field

[0001] This application relates to the field of in vitro diagnostic technologies, and particularly to an optical detection device, a control method thereof, and a sample analyzer. Background Art

[0002] A sample analyzer is an instrument that collects samples and performs detection and analysis on the samples. When a sample analyzer detects a sample, an optical component is often used to perform optical item detection on the sample. The optical component is sensitive to temperature and is greatly affected by temperature. In a low-temperature, high-temperature environment or an environment with rapid temperature changes, the stability of the optical component may be affected.

[0003] In related technologies, in order to correct the influence of temperature changes on the measurement results of the optical component, R & D personnel explored the curve of the temperature and signal changes of the optical component through a large number of experiments, and then made corresponding compensations through this curve to obtain a relatively accurate measurement value. However, the above method has a large workload and low accuracy. Summary of the Invention

[0004] This application provides an optical detection device, a control method thereof, and a sample analyzer. The structure of the optical detection device is simple and the cost is relatively low. Moreover, it can intelligently control the temperature of the optical component within a constant range, improve the stability of the performance of the optical component, and thus improve the accuracy of the detection of the optical component.

[0005] To solve the above technical problems, a technical solution adopted in this application is: to provide an optical detection device, which includes: a housing, an optical component, a temperature sensor, a temperature adjustment mechanism, and a control unit. Among them, the housing forms a sealed cavity; the optical component is disposed in the sealed cavity and is used for performing optical detection on the sample; the temperature sensor is disposed on the housing and is used for sensing the temperature of the housing or the sealed cavity; the temperature adjustment mechanism is disposed on the housing and is used for heating and cooling the housing or the sealed cavity; the control unit is connected to the temperature sensor and the temperature adjustment mechanism, and the control unit is used for: obtaining the actual temperature of the housing or the sealed cavity through the temperature sensor; when it is confirmed that the actual temperature is not within the range of the target temperature, controlling the temperature adjustment mechanism to heat / cool the housing or the sealed cavity so that the actual temperature of the housing or the sealed cavity is within the range of the target temperature.

[0006] Further, the control unit is further used for: when it is confirmed that the actual temperature is lower than the target temperature, controlling the temperature adjustment mechanism to heat the housing or the sealed cavity so that the actual temperature is within the range of the target temperature; when it is confirmed that the actual temperature is higher than the target temperature, controlling the temperature adjustment mechanism to cool the housing or the sealed cavity so that the actual temperature is within the range of the target temperature.

[0007] Further, the control unit is further configured to: when it is confirmed that the actual temperature is lower than the target temperature and the difference between the target temperature and the actual temperature exceeds a first preset value, control the temperature adjustment mechanism to heat the housing or the sealed cavity at a first power; when it is confirmed that the difference between the target temperature and the actual temperature is less than a second preset value, control the temperature adjustment mechanism to heat the housing or the sealed cavity at a second power until the actual temperature is within the range of the target temperature, where the first power is greater than the second power and the first preset value is greater than the second preset value.

[0008] Further, the control unit is further configured to: when it is confirmed that the actual temperature is higher than the target temperature and the difference between the actual temperature and the target temperature exceeds a first preset value, control the temperature adjustment mechanism to cool the housing or the sealed cavity at a first power; when it is confirmed that the difference between the actual temperature and the target temperature is less than a second preset value, control the temperature adjustment mechanism to cool the housing or the sealed cavity at a second power until the actual temperature is within the range of the target temperature, where the first power is greater than the second power and the first preset value is greater than the second preset value.

[0009] Further, the housing includes a bottom plate and an outer shell, the bottom plate is connected to the outer shell to form a sealed cavity, the temperature adjustment mechanism is thermally connected to the bottom plate, and the optical component and the temperature sensor are both disposed on the bottom plate.

[0010] Further, the temperature adjustment mechanism includes a refrigeration heater and a heat dissipation component, one end of the refrigeration heater is thermally connected to the bottom plate to heat or cool the bottom plate, and the other end of the refrigeration heater is connected to the heat dissipation component; alternatively, the temperature adjustment mechanism includes a refrigeration component and a heating component, the refrigeration component and the heating component are connected to the bottom plate, the refrigeration component is used to cool the bottom plate, and the heating component is used to heat the bottom plate.

[0011] Further, the optical detection device further includes a heat-conducting material layer, and the temperature adjustment mechanism is connected to the bottom plate through the heat-conducting material layer.

[0012] Further, a heat-insulating layer is further provided on the inner wall or the outer wall of the housing.

[0013] To solve the above technical problems, another technical solution adopted by the present application is: to provide a sample analyzer, which includes: a liquid path system and the optical detection device of any of the above embodiments, and a part of the pipeline of the liquid path system extends into the sealed cavity of the optical detection device so that the optical component in the sealed cavity performs optical detection on the sample.

[0014] To solve the above technical problems, another technical solution adopted by this application is: to provide a control method for an optical detection device. Based on the optical detection device of any of the above embodiments, the control method includes: obtaining the actual temperature inside the housing or the sealed cavity through a temperature sensor; when it is confirmed that the actual temperature is not within the target temperature range, controlling the temperature adjustment mechanism to heat / cool the housing or the sealed cavity so that the actual temperature inside the housing or the sealed cavity is within the target temperature range.

[0015] Advantages of this application: Different from the prior art, the optical detection device of this application includes: a housing, an optical component, a temperature sensor, a temperature adjustment mechanism, and a control unit. Among them, the housing forms a sealed cavity to seal the optical component. The temperature sensor is used to sense the temperature inside the housing or the sealed cavity; the temperature adjustment mechanism is used to heat and cool the housing or the sealed cavity; the control unit is used to: obtain the actual temperature inside the housing or the sealed cavity through the temperature sensor; when it is confirmed that the actual temperature is not within the target temperature range, control the temperature adjustment mechanism to heat / cool the housing or the sealed cavity so that the actual temperature inside the housing or the sealed cavity is within the target temperature range. The structure of the optical detection device of this application is simple and the cost is low. The optical component is sealed by the housing, reducing the influence of the external environment on the temperature of the optical component. Moreover, the temperature of the housing or the sealed cavity is intelligently controlled through the temperature adjustment mechanism, enabling the temperature of the optical component to be maintained within a constant range, improving the performance stability of the optical component, and thus improving the accuracy of the optical component test. Description of the Drawings

[0016] In order to more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the following will briefly introduce the drawings required for use in the embodiments. Obviously, the drawings in the following description are only some embodiments of this application. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0017] Figure 1 It is a schematic structural diagram of an embodiment of an optical detection device provided by this application;

[0018] Figure 2 is Figure 1 a schematic structural diagram of another perspective of the optical detection device shown;

[0019] Figure 3 is Figure 1 a schematic partial structural diagram of the optical detection device shown;

[0020] Figure 4 It is a schematic flowchart of an embodiment of a control method for an optical detection device provided by this application;

[0021] Figure 5 is Figure 4 a schematic flowchart of an embodiment of step S12 in

[0022] Figure 6 a schematic framework diagram of an embodiment of the sample analyzer provided by the present application. Detailed implementation manners

[0023] To make the above objects, features, and advantages of the present application more obvious and understandable, the following will describe the detailed implementation manners of the present application in conjunction with the accompanying drawings. It can be understood that the specific embodiments described herein are only used to explain the present application, rather than limiting the present application. In addition, it should be noted that for the convenience of description, only parts related to the present application are shown in the drawings, rather than all structures. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0024] The terms "first", "second", etc. in the present application are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "include" and "have" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product, or device that includes a series of steps or units is not limited to the listed steps or units, but may optionally further include steps or units not listed, or may optionally further include other steps or units inherent to these processes, methods, products, or devices.

[0025] Referring to "embodiment" herein means that the specific features, structures, or characteristics described in conjunction with the embodiment may be included in at least one embodiment of the present application. The appearance of this phrase in various positions in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.

[0026] The present application first provides an optical detection device that can protect the temperature of the optical components therein, so that the temperature of the optical components fluctuates within a constant range, the performance of the optical components is stable, and the accuracy of the optical component detection is improved.

[0027] Please refer to Figure 1 、 Figure 2 and Figure 3 as shown, Figure 1 is a schematic structural diagram of an embodiment of an optical detection device provided by the present application, Figure 2 is Figure 1 a schematic structural diagram of another perspective of the optical detection device shown in Figure 3 isFigure 1 Schematic diagram of a partial structure of the optical detection device shown. Specifically, the optical detection device 10 includes a housing 11, an optical component 12, a temperature sensor 13, a temperature adjustment mechanism 14, and a control unit 15.

[0028] Among them, the housing 11 forms a sealed cavity 101. In some embodiments, as Figure 1 shown, the housing 11 may include a bottom plate 111, a first housing 112 bent in a certain way, and a second housing 113 bent in a certain way. The bottom plate 111 connects the first housing 112 and the second housing 113 to enclose and form the sealed cavity 101. The bottom plate 111, the first housing 112, and the second housing 113 are detachably connected. In this way, it is convenient to install circuits and perform maintenance inside the sealed cavity 101. In other embodiments, the first housing 112 and the second housing 113 may also be integrally formed to improve the structural stability of the housing 11.

[0029] The optical component 12 is used for optically detecting a sample. The optical component 12 is disposed inside the sealed cavity 101 to reduce the influence of temperature changes in the external environment on the performance of the optical component 12. The optical component 12 may include a laser light source module 121 and an MPPC (multi-pixel photon counter) fluorescence module 122. In other embodiments, the optical component 12 may also include other optical detection components.

[0030] In Figures 1-3 the shown embodiment, the optical component 12 is disposed on the bottom plate 111. The optical component 12 may be directly in contact with the bottom plate 111, so that the optical component 12 can exchange heat with the bottom plate 111. In other embodiments, the optical component 12 may also be disposed on the first housing 112 or the second housing 113.

[0031] The temperature sensor 13 is disposed on the housing 11. The temperature sensor 13 can be used to sense the temperature inside the housing 11 or the sealed cavity 101. In Figures 1-3 the shown embodiment, the temperature sensor 13 is disposed on the bottom plate 111, and the temperature sensor 13 is used to sense the temperature of the bottom plate 111. In some other embodiments, the probe of the temperature sensor 13 may also extend into the sealed cavity 101 to sense the temperature inside the sealed cavity 101.

[0032] The temperature adjustment mechanism 14 is disposed on the housing 11 and is used to heat and cool the housing 11 or the sealed cavity 101 to adjust the temperature inside the sealed cavity 101, so that the temperature of the optical component 12 is within the target temperature range.

[0033] Specifically, when the temperature of the sealing cavity 101 or the housing 11 is lower than the target temperature, the temperature adjustment mechanism 14 can perform heating to increase the temperature of the housing 11 or the sealing cavity 101. When the temperature of the sealing cavity 101 or the housing 11 is higher than the target temperature range, the temperature adjustment mechanism 14 can perform refrigeration to reduce the temperature of the housing 11 or the sealing cavity 101. The temperature adjustment mechanism 14 of the present application can flexibly adjust the temperature of the housing 11 or the sealing cavity 101 so that the optical component 12 is within the target temperature range, improving the performance stability of the optical component 12, thereby improving the accuracy of the optical component 12 for sample detection.

[0034] Optionally, as Figure 1 shown, the temperature adjustment mechanism 14 may include: a refrigeration heater 141 and a heat dissipation component 142. One end of the refrigeration heater 141 is connected to the bottom plate 111, and the heat dissipation component 142 is connected to the other end of the refrigeration heater 141. The refrigeration heater 141 is used to heat or refrigerate the bottom plate 111. In some embodiments, the refrigeration heater 141 is connected to the outer wall of the bottom plate 111 to facilitate the assembly and disassembly of the refrigeration heater 141 and avoid interference between the refrigeration heater 141 and the optical component 12 in the sealing cavity 101. In other embodiments, the refrigeration heater 141 may also be connected to the inner wall of the bottom plate 111 to reduce the influence of the external environment on the refrigeration heater 141 and reduce the volume of the entire optical detection device 10.

[0035] Specifically, when the refrigeration heater 141 heats the bottom plate 111, the surface of the refrigeration heater 141 in contact with the bottom plate 111 will be heated so that the temperature of the bottom plate 111 reaches the target temperature range. When the refrigeration heater 141 refrigerates the bottom plate 111, the surface of the refrigeration heater 141 in contact with the bottom plate 111 will be refrigerated, and the hot end of the refrigeration heater 141 is connected to the heat dissipation component 142 so that the heat dissipation component 142 dissipates heat from the hot end of the refrigeration heater 141.

[0036] Further, in Figure 1 the shown embodiment, the heat dissipation component 142 includes a radiator 1421, a fan 1422, and a fan mounting plate 1423. Among them, the radiator 1421 is provided at the other end of the refrigeration heater 141, the fan 1422 is provided at one end of the radiator 1421 and the fan 1422 is fixed on the fan mounting plate 1423. When the surface of the refrigeration heater 141 in contact with the bottom plate 111 performs refrigeration, the hot end of the refrigeration heater 141 is connected to the radiator 1421, and the fan 1422 will also be turned on, so that the temperature of the bottom plate 111 reaches the target temperature range. It can be understood that the fan may not be provided in the above heat dissipation component 142, but natural heat dissipation is performed through the radiator 1421.

[0037] In other embodiments, the refrigeration heater 141 may also include a refrigeration component and a heating component. The refrigeration component is used to refrigerate the housing 11 or the sealed cavity 101, and the heating component is used to heat the housing 11 or the sealed cavity 101. The structure of the refrigeration heater 141 only needs to be able to heat and refrigerate the housing 11 or the sealed cavity 101.

[0038] Further, the refrigeration heater 141 may be connected to the bottom plate 111 through the heat-conducting material layer 103. In this way, the heat-conducting coefficient can be increased through the heat-conducting material, and the heat-conducting effect between the refrigeration heater 141 and the bottom plate 111 can be enhanced.

[0039] Further, a heat-insulating layer 102 may be provided on the housing 11. The heat-insulating layer 102 is a heat-insulating material, and the heat-insulating layer 102 can basically isolate the sealed cavity 101 from the outside world, reducing the influence of changes in the external environment on the optical component 12 in the sealed cavity 101.

[0040] Among them, the heat-insulating layer 102 may be provided on the inner side or the outer side of the housing 11. For example, the heat-insulating layer 102 of the first housing 112 and the second housing 113 may be provided on the inner side walls of the first housing 112 and the second housing 113 to protect the heat-insulating layer 102 therein through the first housing 112 and the second housing 113. In other embodiments, the heat-insulating layer 102 on the first housing 112 and the second housing 113 may also be provided on the outer side walls of the first housing 112 and the second housing 113. In this way, the optical component 12 in the sealed cavity 101 can also be heat-insulated.

[0041] When the optical component 12 is provided on the bottom plate 111, the heat-insulating layer on the bottom plate 111 may be provided on the outer side wall of the bottom plate 111 to reduce the influence of the environmental temperature on the temperature of the bottom plate 111.

[0042] The control unit 15 is connected to the temperature adjustment mechanism 14 and the temperature sensor 13. The control unit 15 is used to obtain the actual temperature inside the housing 11 or the sealed cavity 101 from the temperature sensor 13. The control unit 15 can control the temperature adjustment mechanism 14 based on the actual temperature of the sealed cavity 101 or the housing 11, so that the temperature adjustment mechanism 14 heats or cools the sealed cavity 101 or the housing 11.

[0043] Based on the above optical detection device 10, the present application also provides a control method for an optical detection device. Please refer to Figure 4 As shown, the control method for the optical detection device includes:

[0044] S11: Obtain the actual temperature inside the housing or the sealed cavity through the temperature sensor.

[0045] The temperature sensor 13 is provided on the housing 11, and the probe of the temperature sensor 13 can extend into the sealed cavity 101 to sense the temperature inside the sealed cavity 101. The temperature sensor 13 can also be directly connected to the inner side wall of the housing 11 to sense the temperature of the housing 11. For example, when the optical component 12 is provided on the bottom plate 111, the temperature sensor 13 can be provided on the bottom plate 111 to sense the temperature of the bottom plate 111. The temperatures inside the housing 11 and the sealed cavity 101 can reflect the temperature of the optical component 12.

[0046] S12: When it is confirmed that the actual temperature is not within the range of the target temperature, control the temperature adjustment mechanism to heat / cool the housing or the sealed cavity so that the temperature inside the housing or the sealed cavity is within the range of the target temperature.

[0047] After the control unit 15 obtains the actual temperature of the housing 11 or the sealed cavity 101, the control unit 15 can control the temperature adjustment mechanism 14 to heat / cool so that the temperature of the housing 11 or the sealed cavity 101 can be within the range of the target temperature.

[0048] Specifically, when the control unit 15 confirms that the temperature inside the housing 11 or the sealed cavity 101 is lower than the target temperature, it can control the temperature adjustment mechanism 14 to heat so that the temperature of the housing 11 or the sealed cavity 101 rises to within the range of the target temperature. When the control unit 15 confirms that the temperature inside the housing 11 or the sealed cavity 101 is higher than the range of the target temperature, it can control the temperature adjustment mechanism 14 to cool so that the temperature inside the housing 11 or the sealed cavity 101 drops to within the range of the target temperature. In this way, the control unit 15 can flexibly adjust the temperature of the sealed cavity 101 or the housing 11 to keep the temperature of the optical component 12 inside it within a constant range, thereby improving the stability of the performance of the optical component 12.

[0049] Furthermore, when the control unit 15 confirms that the difference between the actual temperature of the sealed cavity 101 or the housing 11 and the target temperature is large, it can control the temperature adjustment mechanism 14 to work at the first power. When it is confirmed that the difference between the actual temperature of the sealed cavity 101 or the housing 11 and the target temperature is small, it can control the temperature adjustment mechanism 14 to work at the second power, where the first power is greater than the second power. In this way, when the temperature difference between the target temperature and the actual temperature is large, the temperature adjustment mechanism 14 works at a high power, which can quickly reduce the difference between the actual temperature and the target temperature and reduce the temperature adjustment duration. When the temperature difference between the actual temperature and the target temperature is small, the control unit 15 controls the temperature adjustment mechanism 14 to work at a low power. In this way, the actual temperature can smoothly enter the range of the target temperature.

[0050] Such as Figure 5As shown, in a specific embodiment, when it is confirmed that the actual temperature is not within the range of the target temperature, the temperature adjustment mechanism is controlled to heat or cool the housing or the sealed cavity so that the temperature in the housing or the sealed cavity is within the range of the target temperature, including:

[0051] S121: When it is confirmed that the actual temperature is lower than the target temperature and the difference between the target temperature and the actual temperature exceeds the first preset value, control the temperature adjustment mechanism to heat the housing or the sealed cavity at the first power. When it is confirmed that the difference between the target temperature and the actual temperature is less than the second preset value, control the temperature adjustment mechanism to heat the housing or the sealed cavity at the second power until the actual temperature is within the range of the target temperature, where the first power is greater than the second power, and the first preset value is greater than the second preset value.

[0052] When the control unit 15 confirms that the actual temperature of the housing 11 or the sealed cavity 101 is lower than the target temperature, it controls the temperature adjustment mechanism 14 to heat the housing 11 or the sealed cavity 101. Specifically, when the target temperature is a temperature range, the actual temperature being lower than the target temperature means that the actual temperature is lower than the minimum value of the target temperature range.

[0053] Furthermore, when the control unit 15 confirms that the difference between the target temperature and the actual temperature exceeds the first preset value, it can be considered that the temperature difference between the target temperature and the actual temperature is large. The control unit 15 can control the temperature adjustment mechanism 14 to heat at the first power with a larger power value to quickly raise the temperature of the housing 11 or the sealed cavity 101 and reduce the duration of temperature adjustment. The first preset value can be greater than or equal to 2°C. For example, the first preset value can be 2°C, 3°C, or 4°C, etc. After the actual temperature value rises, when it is confirmed that the difference between the target temperature and the actual temperature is less than the second preset value, the control unit 15 controls the temperature adjustment mechanism 14 to heat at the second power with a smaller power so that the temperature in the housing 11 or the sealed cavity 101 can reach the range of the target temperature smoothly. The second preset value can be less than or equal to 1°C. For example, the second preset value can be 1°C, 0.5°C, or 0.8°C, etc. In this way, the control unit 15 can intelligently control the temperature of the housing 11 or the sealed cavity 101 to keep the temperature of the optical component 12 within a constant range.

[0054] S122: When it is confirmed that the actual temperature is higher than the target temperature and the difference between the actual temperature and the target temperature exceeds the first preset value, control the temperature adjustment mechanism to cool the housing or the sealed cavity at the first power. When it is confirmed that the difference between the actual temperature and the target temperature is less than the second preset value, control the temperature adjustment mechanism to cool the housing or the sealed cavity at the second power until the actual temperature is within the range of the target temperature, where the first power is greater than the second power, and the first preset value is greater than the second preset value.

[0055] When the control unit 15 confirms that the actual temperature of the housing 11 or the sealed cavity 101 is higher than the target temperature, it controls the temperature adjustment mechanism 14 to cool the housing 11 or the sealed cavity 101. When the target temperature is a temperature range, the actual temperature being higher than the target temperature means that the actual temperature is higher than the maximum value of the target temperature range.

[0056] Further, when the control unit 15 confirms that the difference between the actual temperature and the target temperature exceeds a first preset value, it can be considered that the temperature difference between the target temperature and the actual temperature is large. The control unit 15 can control the temperature adjustment mechanism 14 to cool at a first power with a larger power value to quickly cool the housing 11 or the sealed cavity 101 and reduce the duration of temperature adjustment. The first preset value can be greater than or equal to 2°C. For example, the first preset value can be 2°C, 3°C, or 4°C, etc. After the actual temperature value decreases, when it is confirmed that the difference between the actual temperature and the target temperature is less than a second preset value, the control unit 15 controls the temperature adjustment mechanism 14 to cool at a second power with a smaller power, so that the temperature in the housing 11 or the sealed cavity 101 steadily drops back to the range of the target temperature. The second preset value can be less than or equal to 1°C. For example, the second preset value can be 1°C, 0.5°C, or 0.8°C, etc. In this way, the control unit 15 can intelligently control the temperature of the housing 11 or the sealed cavity 101 to keep the temperature of the optical component 12 within a constant range.

[0057] The optical detection device 10 provided by this application has a simple structure and low cost. Moreover, it can make the temperature of the optical component 12 not affected by the change of the external environment temperature, keep the temperature of the optical component 12 within the range of the target temperature, improve the stability of the optical component 12, and thus improve the accuracy of optical component detection.

[0058] This application also provides a sample analyzer. Please refer to Figure 6 as shown Figure 6 is a schematic framework diagram of an embodiment of a sample analyzer provided by this application. The sample analyzer 60 includes the optical detection device 10 of any of the above embodiments and a liquid path system 61. Part of the pipeline of the liquid path system extends into the sealed cavity of the optical detection device 10 so that the optical component in the sealed cavity can perform optical detection on the sample. For the specific structure of the optical detection device 10, please refer to the introduction of any of the above embodiments and will not be elaborated here.

[0059] The above are only the implementation manners of this application and do not limit the patent scope of this application. All equivalent structural or equivalent process transformations made by using the content of the specification and drawings of this application, or directly or indirectly applied in other related technical fields, are equally included in the patent protection scope of this application.

Claims

1. An optical detection device, characterized in that, the optical detection device includes: a housing, forming a sealed cavity; an optical component, disposed in the sealed cavity for optically detecting a sample; a temperature sensor, disposed on the housing for sensing the temperature of the housing or the sealed cavity; a temperature adjustment mechanism, disposed on the housing for heating and cooling the housing or the sealed cavity; a control unit, connected to the temperature sensor and the temperature adjustment mechanism, the control unit is configured to: acquire the actual temperature of the housing or the sealed cavity through the temperature sensor; when it is confirmed that the actual temperature is not within the range of the target temperature, control the temperature adjustment mechanism to heat / cool the housing or the sealed cavity so that the actual temperature of the housing or the sealed cavity is within the range of the target temperature.

2. The optical detection device according to claim 1, characterized in that, the control unit is further configured to: when it is confirmed that the actual temperature is lower than the target temperature, control the temperature adjustment mechanism to heat the housing or the sealed cavity so that the actual temperature is within the range of the target temperature; when it is confirmed that the actual temperature is higher than the target temperature, control the temperature adjustment mechanism to cool the housing or the sealed cavity so that the actual temperature is within the range of the target temperature.

3. The optical detection device according to claim 2, characterized in that, the control unit is further configured to: when it is confirmed that the actual temperature is lower than the target temperature and the difference between the target temperature and the actual temperature exceeds a first preset value, control the temperature adjustment mechanism to heat the housing or the sealed cavity at a first power, and when it is confirmed that the difference between the target temperature and the actual temperature is less than a second preset value, control the temperature adjustment mechanism to heat the housing or the sealed cavity at a second power until the actual temperature is within the range of the target temperature, wherein the first power is greater than the second power, and the first preset value is greater than the second preset value.

4. The optical detection device according to claim 2, characterized in that, the control unit is further configured to: when it is confirmed that the actual temperature is higher than the target temperature and the difference between the actual temperature and the target temperature exceeds a first preset value, control the temperature adjustment mechanism to cool the housing or the sealed cavity at a first power, and when it is confirmed that the difference between the actual temperature and the target temperature is less than a second preset value, control the temperature adjustment mechanism to cool the housing or the sealed cavity at a second power until the actual temperature is within the range of the target temperature, wherein the first power is greater than the second power, and the first preset value is greater than the second preset value.

5. The optical detection device according to claim 1, characterized in that, the housing includes a bottom plate and an outer shell, the bottom plate is connected to the outer shell to form the sealed cavity, the temperature adjustment mechanism is thermally connected to the bottom plate, and the optical component and the temperature sensor are both disposed on the bottom plate.

6. The optical detection device according to claim 5, characterized in that, the temperature adjustment mechanism includes a refrigeration heater and a heat dissipation component. One end of the refrigeration heater is thermally connected to the bottom plate to heat or cool the bottom plate, and the other end of the refrigeration heater is connected to the heat dissipation component; or, the temperature adjustment mechanism includes a refrigeration component and a heating component. The refrigeration component and the heating component are connected to the bottom plate. The refrigeration component is used to cool the bottom plate, and the heating component is used to heat the bottom plate.

7. The optical detection device according to claim 5, characterized in that, the optical detection device further includes a heat-conducting material layer, and the temperature adjustment mechanism is connected to the bottom plate through the heat-conducting material layer.

8. The optical detection device according to claim 1, characterized in that, a heat-insulating layer is further provided on the inner wall or the outer wall of the housing.

9. A sample analyzer, characterized in that, the sample analyzer includes: a liquid path system and the optical detection device according to any one of claims 1-8. Part of the pipelines of the liquid path system extend into the sealed cavity of the optical detection device, so that the optical components in the sealed cavity can perform optical detection on the sample.

10. A control method for an optical detection device, characterized in that, based on the optical detection device according to any one of claims 1-8, the control method includes: acquiring the actual temperature in the housing or the sealed cavity through a temperature sensor; when it is confirmed that the actual temperature is not within the range of the target temperature, controlling the temperature adjustment mechanism to heat / cool the housing or the sealed cavity so that the actual temperature in the housing or the sealed cavity is within the range of the target temperature.

Images