Blood analysis equipment anti-interference retest method, reagent card, equipment and medium
By setting up a backup counting chamber on the reagent card of the blood analysis equipment, automatic retesting is realized when the item is abnormal, solving the problems of complex operation and waste of samples in the prior art, and improving the testing efficiency and accuracy.
Patent Information
- Application Number
- CN202510211059.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-25
- Publication Date
- 2025-05-30
AI Technical Summary
During the detection process, existing blood analysis equipment has abnormal test results due to impurities interference or reagent card contamination. It usually requires resampling and replacement of reagent card, which is complicated to operate and easily lead to sample waste.
A blood analysis equipment anti-interference retest method is designed. The reagent card is equipped with at least one backup counting chamber. By obtaining the test results of the detection item, it is determined whether there is an abnormality, and the abnormal sample is added to the backup counting chamber for re-detection.
It realizes that when detecting project abnormalities, there is no need to re-prepare samples and replace reagent cards, and automatically retests are performed, saving costs and improving testing efficiency and accuracy.
Smart Images
Figure CN120064683A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of blood detection technology, and particularly relates to an anti-interference retest method, reagent card, device and medium for a blood analysis device. Background Art
[0002] Reagent cards are commonly used in blood detection and are a type of commonly used medical device.
[0003] In existing blood analysis microscopy devices that use reagent cards, when abnormal test results occur due to impurities interference, contamination of the reagent card counting board, etc., it is usually necessary to resample and use a new reagent card for testing.
[0004] However, the method of using a new reagent card for testing has the problems of complex operation and easy sample waste. Summary of the Invention
[0005] Embodiments of the present invention provide an anti-interference retest method, reagent card, device and medium for a blood analysis device, aiming to solve the problems of complex operation and easy sample waste existing in the prior art.
[0006] In a first aspect, embodiments of the present invention provide an anti-interference retest method for a blood analysis device. The reagent card is provided with at least one spare counting cavity, and the method includes:
[0007] Obtain the test result of the detection item;
[0008] Judge whether the test result of the detection item is abnormal;
[0009] If the test result of the detection item is abnormal, add the sample of the detection item with the abnormal test result to the spare counting cavity for re-detection.
[0010] A further technical solution thereof is that the test result includes the measured value of the detection item. Judging whether the test result of the detection item is abnormal includes:
[0011] Judge whether the measured value of the detection item is within the preset normal value range;
[0012] If the measured value of the detection item is not within the preset normal value range, it is determined that the test result of the detection item is abnormal.
[0013] A further technical solution thereof is that adding the sample of the detection item with the abnormal test result to the spare counting cavity for re-detection includes:
[0014] Judge whether the number of detection items with abnormalities is 1;
[0015] If the number of the detected items with anomalies is 1, add the sample of the detected item with anomalies to the spare counting cavity for re-detection.
[0016] A further technical solution thereof is that adding the sample of the detected item with abnormal test results to the spare counting cavity for re-detection further includes:
[0017] If the number of the detected items with anomalies is multiple, screen out the target detected item with the highest priority from the multiple detected items with anomalies according to the preset priority order;
[0018] Add the sample of the target detected item to the spare counting cavity for re-detection.
[0019] A further technical solution thereof is that the detected items include at least one of red blood cell detection, white blood cell detection, and platelet detection.
[0020] In a second aspect, an embodiment of the present invention provides a reagent card applied to the method described in the first aspect, and the reagent card is provided with at least one spare counting cavity.
[0021] A further technical solution thereof is that the reagent card further includes a sample cavity, a platelet reaction cavity, a white blood cell reaction cavity, a red blood cell counting cavity, a white blood cell counting cavity, and a platelet counting cavity.
[0022] In a third aspect, an embodiment of the present invention further provides a blood analysis device anti-interference re-detection device, which includes a unit for executing the above method.
[0023] In a fourth aspect, an embodiment of the present invention further provides a computer device, which includes a memory and a processor, and a computer program is stored on the memory, and when the processor executes the computer program, the above method is implemented.
[0024] In a fifth aspect, an embodiment of the present invention further provides a computer-readable storage medium, and the storage medium stores a computer program, and when the computer program is executed by a processor, the above method can be implemented.
[0025] An anti-interference retest method, reagent card, device and medium for a blood analysis device are provided in an embodiment of the present invention. The reagent card is provided with at least one spare counting cavity, and the method includes the following steps: obtaining a test result of a test item; determining whether the test result of the test item is abnormal; if the test result of the test item is abnormal, adding the sample of the test item with the abnormal test result to the spare counting cavity for re-detection. It can be seen that when the test item is abnormal, the present invention can re-measure the abnormal test item based on the spare counting cavity on the reagent card. The whole process is fully automatic without the need for user operation, without adding samples and replacing new reagent cards, saving costs while having higher test efficiency and accuracy. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for description in the embodiments will be briefly introduced below. Obviously, the drawings in the following description are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.
[0027] Figure 1 It is a schematic flowchart of an anti-interference retest method for a blood analysis device provided in an embodiment of the present invention;
[0028] Figure 2 It is a schematic structural diagram of a reagent card provided in an embodiment of the present invention;
[0029] Figure 3 It is a schematic structural diagram of a motion mechanism provided in an embodiment of the present invention;
[0030] Figure 4 It is a schematic block diagram of a computer device provided in an embodiment of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0031] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention. Obviously, the described embodiments are some, but not all, of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts fall within the protection scope of the present invention.
[0032] It should be understood that when used in this specification and the appended claims, the terms "comprises" and "comprising" indicate the presence of the described features, wholes, steps, operations, elements, and / or components, but do not exclude the presence or addition of one or more other features, wholes, steps, operations, elements, components, and / or their combinations.
[0033] It should also be understood that the terms used in the specification of the present invention are for the purpose of describing specific embodiments only and are not intended to limit the present invention. As used in the specification of the present invention and the appended claims, unless the context clearly indicates otherwise, the singular forms "a", "an" and "the" are intended to include the plural forms.
[0034] It should be further understood that the term "and / or" used in the specification of the present invention and the appended claims refers to any combination and all possible combinations of one or more of the associated listed items, and includes these combinations.
[0035] As used in this specification and the appended claims, the term "if" may be interpreted, depending on the context, as "when", "once", "in response to determining" or "in response to detecting". Similarly, the phrase "if determined" or "if [the described condition or event] is detected" may be interpreted, depending on the context, as meaning "once determined", "in response to determining", "once [the described condition or event] is detected" or "in response to detecting [the described condition or event]".
[0036] Please refer to Figure 1 , an anti-interference retest method for a blood analysis device is provided in an embodiment of the present invention. As Figure 1 shown, the method includes the following steps:
[0037] S1, obtaining the test results of the test items.
[0038] In specific implementation, the test items include at least one of red blood cell detection, white blood cell detection, and platelet detection. The reagent card can support multiple test items, for example, it can support the tests of platelets, white blood cells, and red blood cells simultaneously. The blood analysis device tests the platelets, white blood cells, and red blood cells in the blood sample respectively to obtain the test results.
[0039] In an embodiment of the present invention, in addition to the red blood cell counting chamber, white blood cell counting chamber, and platelet counting chamber, the reagent card is additionally equipped with at least one spare counting chamber. The spare counting chamber is used to re-measure when the test items are abnormal, so that there is no need to prepare a new reagent card again, saving costs and having higher test efficiency.
[0040] S2, determining whether there is an abnormality in the test results of the test items.
[0041] In specific implementation, it is determined whether there is an abnormality in the test results of the test items. If there is an abnormality, the test items are re-detected.
[0042] The test results of the detection items include the measured values of the detection items, such as the measured values of platelets, white blood cells, and red blood cells. Whether there is an abnormality in the test results is judged based on the measured values of the detection items.
[0043] For example, in some embodiments, such as this embodiment, the above step of "judging whether there is an abnormality in the test results of the detection items" specifically includes:
[0044] S21, judging whether the measured value of the detection item is within the preset normal value range.
[0045] In specific implementation, the normal value range of the measured value of the detection item can be set by those skilled in the art, and the present invention does not specifically limit this.
[0046] Specifically, after obtaining the measured value of the detection item, judge whether the measured value of the detection item is within the preset normal value range.
[0047] S22, if the measured value of the detection item is not within the preset normal value range, determine that there is an abnormality in the test results of the detection item.
[0048] In specific implementation, if the measured value of the detection item is not within the preset normal value range, determine that there is an abnormality in the test results of the detection item.
[0049] Specifically, the detection of abnormalities is mainly judged by the measured values of the detection items. For example, extremely low values of red blood cells and white blood cells may be caused by abnormal samples, dust and dirt on the surface of the counting plate, which result in failed focusing and no cell images being captured, as well as abnormal movement, etc. The present invention mainly conducts retesting for the situation where clear cell images cannot be obtained due to failed focusing in the case of dust and dirt on the surface of the counting plate.
[0050] S23, if the measured value of the detection item is within the preset normal value range, determine that the test results of the detection item are normal.
[0051] In specific implementation, if the measured value of the detection item is within the preset normal value range, determine that the test results of the detection item are normal.
[0052] S3, if there is an abnormality in the test results of the detection item, add the sample of the detection item with abnormal test results to the spare counting cavity for re-detection.
[0053] In specific implementation, if there is an abnormality in the test results of the detection item, add the sample of the detection item with abnormal test results to the spare counting cavity for re-detection, so that there is no need to prepare a new reagent card again, saving costs and having higher test efficiency.
[0054] For example, in some embodiments, such as the present embodiment, the above step of "adding the sample of the test item with abnormal test results to the spare counting cavity for re-detection" specifically includes:
[0055] S31, determining whether the number of the test items with abnormalities is 1.
[0056] In specific implementation, the number of the test items with abnormalities can be one or more. In the embodiments of the present invention, first determine whether the number of the test items with abnormalities is one or more.
[0057] S32, if the number of the test items with abnormalities is 1, adding the sample of the test item with abnormalities to the spare counting cavity for re-detection.
[0058] In specific implementation, if the number of the test items with abnormalities is 1, directly add the sample of the test item with abnormalities to the spare counting cavity for re-detection.
[0059] For example, if only the test result of red blood cells is abnormal, then re-detect the red blood cells based on the spare counting cavity.
[0060] S33, if the number of the test items with abnormalities is greater than 1, screening out the target test item with the highest priority from the multiple test items with abnormalities according to the preset priority order.
[0061] In specific implementation, the priority order can be preset by those skilled in the art, and the present invention does not specifically limit this.
[0062] If the number of the test items with abnormalities is greater than 1, then screen out the target test item with the highest priority from the multiple test items with abnormalities according to the preset priority order.
[0063] S34, adding the sample of the target test item to the spare counting cavity for re-detection.
[0064] In specific implementation, add the sample of the target test item to the spare counting cavity for re-detection.
[0065] Specifically, when an abnormal measurement value appears, the user is prompted to retest. The motion mechanism is reset, and the sample of the test item (one of red blood cells, white blood cells, and platelets) that needs to be retested is added to the spare counting cavity. Photos are taken and subsequent calculations are performed in the spare counting cavity, and finally the value is output. If multiple test items are abnormal, the system determines the priority, and the item with the highest priority of abnormality is placed in the spare counting cavity for retesting, and the other abnormal test items are retested once on the original counting cavity (refocusing and taking pictures). The retest time for a single type is about 1 minute, and the retest for all three types is about 3 minutes.
[0066] Application scenario: Taking the example of the counting plate being contaminated when touched
[0067] Specifically, when the user accidentally touches a part of the counting plate during the test process, fingerprints and other contaminants are generated on the counting plate (for example, touching the white blood cell detection area). At this time, during the normal detection when taking pictures of white blood cells, the focusing may fail, resulting in a picture without the content of white blood cells being taken, and white blood cells cannot be recognized, resulting in an abnormal value and entering the retest function.
[0068] At the beginning of the retest, the user is prompted on the page: "Retesting...". The instrument motion mechanism is reset, and the white blood cell sample is added to the spare counting cavity, and the process of taking pictures and recognizing white blood cells is performed again in the spare counting cavity. The whole process is fully automatic, without the need for user operation, and there is no need to add samples or replace new reagent cards.
[0069] An embodiment of the present invention provides a method for anti-interference retesting of a blood analysis device. The reagent card is provided with at least one spare counting cavity. The method includes the following steps: obtaining the test result of the test item; determining whether there is an abnormality in the test result of the test item; if there is an abnormality in the test result of the test item, adding the sample of the test item with the abnormal test result to the spare counting cavity for re-detection. It can be seen that when the test item is abnormal, the present invention can re-retest the abnormal test item based on the spare counting cavity on the reagent card. The whole process is fully automatic, without the need for user operation, and there is no need to add samples or replace new reagent cards, saving costs while having higher test efficiency and accuracy.
[0070] Correspondingly, referring to Figure 2 , an embodiment of the present invention provides a reagent card. The reagent card is applied to the method for anti-interference retesting of the blood analysis device proposed in the above embodiment. The reagent card is provided with at least one spare counting cavity 60.
[0071] Further, the reagent card further includes a sample chamber 10, a platelet reaction chamber 30, a white blood cell reaction chamber 20, a red blood cell counting chamber 50, a white blood cell counting chamber 40, and a platelet counting chamber 70. The sample chamber 10 is used to store blood samples. The platelet reaction chamber 30 is used for platelet reactions. The white blood cell reaction chamber 20 is used for white blood cell reactions. The red blood cell counting chamber 50, the white blood cell counting chamber 40, and the platelet counting chamber 70 are respectively used for detecting red blood cells, white blood cells, and platelets. The spare counting chamber 60 is used to re-measure the test item when the test item is abnormal.
[0072] Further, referring to Figure 3 , a motion mechanism is required for the movement and measurement of the reagent card. The motion mechanism includes an X-axis, a Y-axis, a Z-axis, a reagent card holder 100, and a camera assembly 200. The camera assembly 100 includes a camera and a lens. The reagent card holder 100 is used to fix the reagent card. The X-axis, Y-axis, and Z-axis are respectively driven by an X-axis motor 300, a Y-axis motor 400, and a Z-axis motor 500. The X-axis motor and the Y-axis motor are used to move the reagent card so that the chamber to be photographed is under the lens of the camera assembly. The Z-axis motor is used to move the lens of the camera assembly for focusing.
[0073] Corresponding to the above anti-interference retest method for a blood analysis device, the present invention also provides an anti-interference retest device for a blood analysis device. The anti-interference retest device for a blood analysis device includes a unit for executing the above anti-interference retest method for a blood analysis device. The anti-interference retest device for a blood analysis device can be configured in terminals such as desktop computers, tablet computers, laptops, etc. Specifically, the anti-interference retest device for a blood analysis device includes:
[0074] An acquisition unit for acquiring the test result of a test item;
[0075] A judgment unit for judging whether there is an abnormality in the test result of the test item;
[0076] A retest unit for adding the sample of the test item with an abnormal test result to the spare counting chamber for re-detection if the test result of the test item is abnormal.
[0077] In some embodiments, such as this embodiment, the test result includes the measured value of the test item. Judging whether there is an abnormality in the test result of the test item includes:
[0078] Judging whether the measured value of the test item is within a preset normal value range;
[0079] If the measured value of the test item is not within the preset normal value range, it is determined that the test result of the test item is abnormal.
[0080] In some embodiments, such as this embodiment, adding the sample of the test item with abnormal test results to the spare counting cavity for re-detection includes:
[0081] Determining whether the number of test items with abnormalities is 1;
[0082] If the number of test items with abnormalities is 1, adding the sample of the test item with abnormalities to the spare counting cavity for re-detection.
[0083] In some embodiments, such as this embodiment, adding the sample of the test item with abnormal test results to the spare counting cavity for re-detection further includes:
[0084] If the number of test items with abnormalities is multiple, screening out the target test item with the highest priority from the multiple test items with abnormalities according to the preset priority order;
[0085] Adding the sample of the target test item to the spare counting cavity for re-detection.
[0086] In some embodiments, such as this embodiment, the test item includes at least one of red blood cell detection, white blood cell detection, and platelet detection.
[0087] It should be noted that those skilled in the art can clearly understand that the specific implementation processes of the above anti-interference re-measurement device of the blood analysis device and each unit can refer to the corresponding descriptions in the foregoing method embodiments. For the convenience and brevity of description, they will not be elaborated here.
[0088] The above anti-interference re-measurement device of the blood analysis device can be implemented in the form of a computer program, and this computer program can run on a computer device as shown in Figure 4 shown.
[0089] Please refer to Figure 4 , Figure 4 is a schematic block diagram of a computer device provided by an embodiment of the present application. The computer device 500 can be a terminal or a server. Among them, the terminal can be an electronic device with a communication function such as a smart phone, a tablet computer, a notebook computer, a desktop computer, a personal digital assistant, and a wearable device. The server can be an independent server or a server cluster composed of multiple servers.
[0090] The computer device 500 includes a processor 502, a memory, and a network interface 505 connected through a system bus 501. Among them, the memory can include a non-volatile storage medium 503 and an internal memory 504.
[0091] The non-volatile storage medium 503 can store an operating system 5031 and a computer program 5032. When the computer program 5032 is executed, it can cause the processor 502 to execute an anti-interference retest method for a blood analysis device.
[0092] The processor 502 is used to provide computing and control capabilities to support the operation of the entire computer device 500.
[0093] The internal memory 504 provides an environment for the operation of the computer program 5032 in the non-volatile storage medium 503. When the computer program 5032 is executed by the processor 502, it can cause the processor 502 to execute an anti-interference retest method for a blood analysis device.
[0094] The network interface 505 is used for network communication with other devices. Those skilled in the art can understand that the above structure is only a block diagram of some structures related to the solution of the present application, and does not constitute a limitation on the computer device 500 to which the solution of the present application is applied. The specific computer device 500 may include more or fewer components than those shown in the figure, or combine some components, or have different component arrangements.
[0095] Among them, the processor 502 is used to run the computer program 5032 stored in the memory to implement the steps of an anti-interference retest method for a blood analysis device proposed in any of the above embodiments.
[0096] It should be understood that in the embodiments of the present application, the processor 502 may be a central processing unit (CPU), and the processor 502 may also be other general-purpose processors, digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. Among them, the general-purpose processor may be a microprocessor or the processor may also be any conventional processor, etc.
[0097] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. The computer program can be stored in a storage medium, and the storage medium is a computer-readable storage medium. The computer program is executed by at least one processor in the computer system to implement the process steps of the embodiments of the above method.
[0098] Therefore, the present invention also provides a storage medium. The storage medium may be a computer-readable storage medium. The storage medium stores a computer program. When the computer program is executed by a processor, the processor is caused to execute the steps of a method for anti-interference retest of a blood analysis device proposed in any of the above embodiments.
[0099] The storage medium is a physical, non-transitory storage medium, such as a USB flash drive, a portable hard drive, a read-only memory (ROM), a magnetic disk, or an optical disc, etc., which are various physical storage media that can store program codes. The computer-readable storage medium may be non-volatile or volatile.
[0100] Those of ordinary skill in the art can realize that the units and algorithm steps of the examples described in combination with the embodiments disclosed herein can be implemented by electronic hardware, computer software, or a combination of the two. To clearly illustrate the interchangeability of hardware and software, the components and steps of the examples have been generally described according to their functions in the above description. Whether these functions are executed in a hardware or software manner depends on the specific application and design constraints of the technical solution. A professional person can use different methods to implement the described functions for each specific application, but such implementation should not be considered to exceed the scope of the present invention.
[0101] In several embodiments provided by the present invention, it should be understood that the disclosed devices and methods can be implemented in other ways. For example, the device embodiments described above are merely illustrative. For example, the division of each unit is only a logical function division, and there may be other division methods in actual implementation. For example, multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed.
[0102] The steps in the method embodiments of the present invention can be adjusted, combined, and deleted according to actual needs. The units in the device embodiments of the present invention can be combined, divided, and deleted according to actual needs. In addition, the functional units in each embodiment of the present invention can be integrated into one processing unit, or each unit can exist physically alone, or two or more units can be integrated into one unit.
[0103] If the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a storage medium. Based on such an understanding, the technical solution of the present invention, in essence, or the part that contributes to the prior art, or all or part of the technical solution can be embodied in the form of a software product. The computer software product is stored in a storage medium and includes several instructions for causing a computer device (which may be a personal computer, a terminal, or a network device, etc.) to execute all or part of the steps of the methods described in the various embodiments of the present invention.
[0104] In the above embodiments, the descriptions of the various embodiments have their own emphases. For the parts not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.
[0105] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, provided that these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention is also intended to include these changes and modifications.
[0106] As described above, the above are only the specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention can easily think of various equivalent modifications or substitutions, and these modifications or substitutions should all be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims
1. A blood analysis equipment anti-interference retest method, characterized in that: The reagent card is provided with at least one spare counting cavity, and the method comprises: Obtain test results of test items; Determine whether there are any abnormalities in the test results of the detection items; If the test result of the detection item is abnormal, the sample of the detection item with the abnormal test result is added to the spare counting cavity for re-detection.
2. The anti-interference retest method of blood analysis equipment according to claim 1, characterized in that: The test result includes a measurement value of the test item, and judging whether the test result of the test item is abnormal includes: Determine whether the measured value of the detection item is within a preset normal value range; If the measured value of the detection item is not within the preset normal value range, it is determined that the test result of the detection item is abnormal.
3. The anti-interference retest method of blood analysis equipment according to claim 1, characterized in that: The step of adding the sample of the test item with abnormal test results to the spare counting cavity for retesting includes: Determine whether the number of the detection items with abnormalities is 1; If the number of the detection items with abnormalities is 1, the samples of the detection items with abnormalities are added to the spare counting cavity for re-detection.
4. The anti-interference retest method of blood analysis equipment according to claim 3, characterized in that: The adding of the sample of the test item with abnormal test results to the spare counting cavity for retesting also includes: If there are multiple detection items with abnormalities, select the target detection item with the highest priority from the multiple detection items with abnormalities according to the preset priority order; The sample of the target detection item is added to the spare counting cavity for re-detection.
5. The anti-interference retest method of blood analysis equipment according to claim 1, characterized in that: The detection items include at least one of red blood cell detection, white blood cell detection and platelet detection.
6. A reagent card used in the method according to any one of claims 1 to 5, characterized in that: The reagent card is provided with at least one spare counting cavity.
7. The reagent card according to claim 6, characterized in that: The reagent card also includes a sample chamber, a platelet reaction chamber, a leukocyte reaction chamber, a red blood cell counting chamber, a leukocyte counting chamber and a platelet counting chamber.
8. A blood analysis equipment anti-interference retest device, characterized in that: The method comprises a unit for executing the method according to any one of claims 1 to 7.
9. A computer device, characterized in that: The computer device includes a memory and a processor, the memory stores a computer program, and the processor implements the method according to any one of claims 1 to 7 when executing the computer program.
10. A computer-readable storage medium, characterized in that: The storage medium stores a computer program, and when the computer program is executed by a processor, the method according to any one of claims 1 to 7 can be implemented.