Penthorum chinense pursh solid beverage and processing equipment thereof

Abstract

The invention relates to the field of penthorum chinense pursh processing, and discloses a penthorum chinense pursh solid beverage and processing equipment thereof, the penthorum chinense pursh solid beverage comprises the following materials: 30-60 parts of penthorum chinense pursh extract; 15-25 parts of radix puerariae powder; 10 to 15 parts of lycium barbarum polysaccharide concentrate; through compounding of the penthorum chinense pursh extract, the radix puerariae powder, the lycium barbarum polysaccharide, the nano lecithin and other components, efficient absorption and multi-target regulation of liver-protecting active components are realized by utilizing a nano delivery system and a synergistic effect of the components; the invention discloses penthorum chinense pursh solid beverage processing equipment. The driving rod coaxially penetrates through the top and the bottom of the processing barrel, and the driving rod is arranged to rotate in the processing barrel; and the crushing structure is mounted on the driving rod. The squeezing plate and the separating plate are synchronously close to squeeze and are matched with the dynamic crushing of the movable cutter, so that juice is quickly separated out and discharged through the separating holes under the double action of continuous shearing and squeezing of materials, and the viscosity of the materials is reduced through real-time juice separation.

Description

Technical Field

[0001] The present invention relates to the field of processing of chrysanthemum officinale, and in particular to a chrysanthemum officinale solid beverage and processing equipment thereof. Background Art

[0002] Ganhuangcao is rich in flavonoid active ingredients such as quercetin, kaempferol, gallic acid, etc. It is a high-quality raw material for developing beverages. Solid beverages have the advantages of high portability, long shelf life, and easy re-dissolution, becoming an important direction for the deep processing of Ganhuangcao. The processing of Ganhuangcao solid beverage mainly includes the following steps: After the fresh Ganhuangcao is washed, it is crushed into particles by a grinder and then squeezed to extract the pulp; the extruded pulp is filtered through a vibrating screen and concentrated to the solid content by a double-effect vacuum concentrator; the concentrated liquid is made into powder by spray drying, or vacuum freeze-dried after pre-freezing; after the dry powder is mixed with the auxiliary materials, it is made into granules by wet granulation and fluidized bed drying.

[0003] The publication number CN217287406U disclosed a separation and filtration device for preparing a functional beverage made from the herb. The device pours the extract initially prepared from the herb into the cover from the feed port, and allows the finely ground raw materials and impurities mixed in the extract to remain on the upper surface of the filter plate. The motor is then started so that its output shaft drives the rotating block to rotate, and the grinding plate is driven to rotate at the same time. During the rotation of the grinding plate, the finely ground raw materials on the surface of the filter plate are ground, thereby extracting the finely ground raw materials, which then drip from the filter screen to the surface of the filter membrane, and then the extract is filtered by the filter membrane and flows to the lower inner wall of the filter tank, and finally discharged and collected from the discharge port.

[0004] The juice produced by the existing processing equipment during the crushing process cannot be separated in real time, and the yellow grass material will produce juice with high viscosity during the crushing process. If the juice is not separated from the material in time, the juice will mix with the material to form liquid-solid adhesion. Due to the centrifugal force, the fiber particles will gather to the edge of the cavity, forming a crushing blind area. Summary of the invention

[0005] In order to solve the problems that the existing solid beverages of Ganhuangcao are mostly single ingredients or simply compounded, the bioavailability of flavonoids is low, the synergistic liver protection effect of multiple ingredients is insufficient, and it is difficult to balance taste and functionality, as well as to solve the problem that the juice produced by the existing processing equipment during the crushing process cannot be separated in real time, the juice will mix with the material to form liquid-solid adhesion, and the fiber particles will gather to the edge of the cavity due to the centrifugal force to form a crushing blind area, the present invention is achieved through the following technical scheme.

[0006] On the one hand, the present invention provides a solid beverage of Herba Lycopodii, which is composed of the following materials: 30-60 parts of Herba Lycopodiellae extract; 15-25 parts of kudzu root powder; 10-15 parts of wolfberry polysaccharide concentrate; 10 - 15 parts of seabuckthorn fruit powder; 5 - 8 parts of tea polyphenol microcapsules; 5 - 10 parts of Agaricus blazei Murill β - glucan; 2 - 6 parts of Cordyceps militaris adenosine extract; 1 - 5 parts of mogroside; 3 - 8 parts of nanoscale lecithin; 1 - 3 parts of selenium - rich yeast; 2 - 5 parts of magnesium ascorbyl phosphate; 0.5 - 2 parts of black pepper extract.

[0007] A kind of solid drink of Penthorum chinense Pursh provided by the present invention, through the compounding of Penthorum chinense Pursh extract with components such as kudzu root powder, wolfberry polysaccharide, and nanoscale lecithin, utilizes the nanodelivery system and the synergistic effect of components to achieve the efficient absorption and multi - target regulation of liver - protecting active ingredients. The nanoscale lecithin and black pepper extract form a liposome delivery system to encapsulate flavonoid components, break through the intestinal barrier, and improve the bioavailability of active ingredients such as quercetin; the Cordyceps militaris adenosine extract and selenium - rich yeast synergistically regulate key enzymes for alcohol metabolism, accelerate ethanol decomposition, and reduce liver damage; mogroside replaces traditional sucrose, which can improve the taste while avoiding the burden of sugar on the liver, and is suitable for people with alcoholic liver injury.

[0008] On the other hand, the present invention also provides a processing device for the solid drink of Penthorum chinense Pursh, including: a processing barrel; a driving rod coaxially penetrating through the top and bottom of the processing barrel, and the driving rod is arranged to rotate within the processing barrel; a crushing structure installed on the driving rod, the crushing structure includes two moving knives connected to the driving rod, and the two moving knives generate radial shear force as they rotate with the driving rod; an extrusion assembly including an extrusion plate and a separation plate, the extrusion plate and the separation plate are arranged on the driving rod, the crushing structure is arranged between the extrusion plate and the separation plate, the separation plate is provided with separation holes, and the extrusion plate and the separation plate are arranged to be able to approach or move away from each other simultaneously for extruding the Penthorum chinense Pursh material and separating the juice; a driving mechanism installed within the processing barrel, and the driving mechanism is connected to the extrusion plate and the separation plate for driving the extrusion plate and the separation plate to move.

[0009] Preferably, the driving rod includes: a moving groove opened on the surface of the driving rod; a slider connected within the moving groove, and the slider is connected to the moving knife.

[0010] Preferably, the driving rod further includes: an inner cavity opened on the driving rod, a collection port is opened on the inner wall of the inner cavity, and an opening is provided at the bottom of the inner cavity; a piston installed within the inner cavity; a connecting rope, one end of which is installed on the slider, and the other end penetrates through the moving groove and extends into the inner cavity and is connected to the piston.

[0011] Preferably, the drive rod further includes: a first one-way valve installed in the collection port, with the liquid outlet of the first one-way valve facing the inner cavity; a second one-way valve installed at the bottom opening of the inner cavity, with the liquid inlet of the second one-way valve facing the inner cavity; and an elastic member with one end installed on the inner wall of the inner cavity and the other end installed on the piston.

[0012] Preferably, the slider includes: an inclined block installed at the bottom of the slider, and the inclined block is arranged in the moving groove.

[0013] Preferably, the drive mechanism includes: a first power source installed on the top wall of the processing barrel, with the power shaft of the first power source connected to the extrusion plate; and a second power source installed at the bottom of the processing barrel, with the power shaft of the second power source connected to the separation plate.

[0014] Preferably, it further includes: a fourth power source installed in the processing barrel; a first transmission wheel installed on the power shaft of the fourth power source; and a second transmission wheel installed on the drive rod, with the second transmission wheel connected to the first transmission wheel by a belt.

[0015] Preferably, the crushing structure further includes: a fixed knife installed on the drive rod, and the fixed knife is located between two moving knives.

[0016] Preferably, the drive mechanism includes: a third power source installed on the processing barrel; a first connecting rod with one end installed on the extrusion plate and the other end provided with a telescopic groove; a second connecting rod with one end installed on the separation plate and the other end connected in the telescopic groove; and a lead screw with one end connected to the power shaft of the third power source and the other end passing through the extrusion plate and threadedly connected to the second connecting rod.

[0017] A processing device for Patrinia scabra solid beverage proposed by the present invention, through the synchronous approach and extrusion of the extrusion plate and the separation plate, combined with the dynamic crushing of the moving knives, enables the juice to be quickly separated out and discharged through the separation holes under the dual actions of continuous shearing and extrusion, reduces the adhesion of the material to the inner wall of the device, the real-time juice separation reduces the viscosity of the material, reduces the load on the moving knives, the two moving knives are driven by the extrusion plate to move closer to each other when rotating at high speed, forming a combined force of rotational shearing and axial compression. When the distance between the moving knives is large, the high-speed rotation can cut large stems and leaves, and when the extrusion plate pushes the distance between the moving knives to shrink, it further shears the material and completely destroys the cell wall. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic three-dimensional structure diagram proposed by the present invention.

[0019] Figure 2 It is a schematic cross-sectional view of the processing barrel proposed by the present invention.

[0020] Figure 3 It is a schematic structure diagram of the processing barrel, the extrusion plate and the separation plate proposed by the present invention.

[0021] Figure 4 Schematic cross-sectional view of the extrusion plate and the separation plate proposed by the present invention.

[0022] Figure 5 Schematic structural view of the driving rod, the extrusion plate, the separation plate and the crushing structure proposed by the present invention.

[0023] Figure 6 Partial enlarged cross-sectional view of the driving rod and the separation plate proposed by the present invention.

[0024] Figure 7 Schematic structural view of the first one-way valve proposed by the present invention.

[0025] Figure 8 Schematic structural view of the driving mechanism in the fourth embodiment of the present invention.

[0026] Figure 9 is Figure 8 Schematic cross-sectional view of the first connecting rod and the second connecting rod in

[0027] Figure 10 Experimental result diagram of Experiment 1 in Example 1.

[0028] Figure 11 Experimental result diagram of Experiment 2 in Example 1.

[0029] Figure 12 Experimental result diagram of the control experiment of Experiment 2 in Example 1.

[0030] Figure 13 Experimental result diagram of Experiment 3 in Example 1.

[0031] Figure 14 Experimental result diagram of Experiment 4 in Example 1.

[0032] Figure 15 Bioavailability data diagram in Example 2.

[0033] Figure 16 Animal experiment data diagram in Example 2.

[0034] The reference numerals in the figure are: 100, processing barrel; 101, first power source; 102, second power source; 103, third power source; 104, lead screw; 105, first connecting rod; 106, second connecting rod; 200, extrusion plate; 300, separation plate; 400, driving rod; 401, moving groove; 402, slider; 403, inclined block; 404, inner cavity; 405, piston; 406, elastic member; 407, connecting rope; 408, first one-way valve; 409, second one-way valve; 500, Fourth power source; 501, First driving wheel; 502, Second driving wheel; 600, Crushing structure; 601, Fixed knife; 602, Moving knife. Detailed implementation manner

[0035] The present invention will be further described below in conjunction with specific embodiments. It should be understood that these embodiments are only used to illustrate the present invention and not to limit the protection scope of the present invention.

[0036] The following illustrates the implementation manner of the present invention through specific examples. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through different specific implementation manners. Various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention.

[0037] Example 1: Refer to Figures 10 - 14 , A kind of solid beverage of Penthorum chinense, which is composed of the following materials: 45 parts of Penthorum chinense extract; 15 parts of kudzu root powder; 10 parts of wolfberry polysaccharide concentrate; 10 parts of seabuckthorn fruit powder; 5 parts of tea polyphenol microcapsules; 5 parts of Agaricus blazei Murill β-glucan; 2 parts of Cordyceps militaris adenosine extract; 1 part of mogroside; 3 parts of nanoscale lecithin; 1 part of selenium-enriched yeast; 2 parts of magnesium ascorbyl phosphate; 1 part of black pepper extract.

[0038] Among them, the flavonoid content in the Penthorum chinense extract is 30%, and the Penthorum chinense extract can inhibit liver fibrosis and promote hepatocyte regeneration; The puerarin content in the kudzu root powder is 8%, and the kudzu root powder can relieve alcoholic liver injury; The purity of the wolfberry polysaccharide concentrate is 50%. Wolfberry polysaccharide is the core active ingredient of wolfberry and has the effect of anti-fatigue; The vitamin C content in the seabuckthorn fruit powder is 500mg / 100g. The seabuckthorn fruit powder is rich in vitamin C, and its acidic components can adjust the taste and improve the palatability of the beverage; The tea polyphenol microcapsules are of the sustained-release type. Tea polyphenols are strong antioxidants, and the microencapsulation technology can protect the stability of tea polyphenols; The sweetness substitution rate of mogroside is 90%. Mogroside is a natural sweetener with zero calories and no blood sugar increase, suitable for people with blood sugar control. At the same time, it improves the sweetness of beverages and avoids the burden on the liver caused by traditional sugars. The selenium content in selenium-enriched yeast is 1000 μg / g. Magnesium ascorbyl phosphate is heat-stable. The piperine content in black pepper extract is 95%.

[0039] The solid drink of Penthorum chinense Pursh of the present invention is based on the "gut-liver axis" co-regulation mechanism, and realizes the trinity effect of "liver protection-immunity-antifatigue" through three technical breakthroughs of delivery synergism, metabolic coordination and targeted protection. The specific experiments are as follows: Experiment 1: Verification of the synergistic antioxidant effect of the composition Purpose: To verify the synergistic antioxidant ability of Penthorum chinense Pursh extract + seabuckthorn fruit powder + green tea polyphenol microcapsules.

[0040] 1.1 Experimental materials and instruments Test samples: 45 parts of Penthorum chinense Pursh extract, 15 parts of kudzu root powder, 10 parts of wolfberry polysaccharide concentrate, 10 parts of seabuckthorn fruit powder, 5 parts of tea polyphenol microcapsules, 5 parts of Agaricus blazei Murill β-glucan, 2 parts of Cordyceps militaris adenosine extract, 1 part of mogroside, 3 parts of nanoscale lecithin, 1 part of selenium-enriched yeast, 2 parts of magnesium ascorbyl phosphate and 1 part of black pepper extract.

[0041] Control sample: Commercially available liver protection tablets (containing 80% silybin).

[0042] Reagents: DPPH (Sigma D9132), DMEM medium (Gibco), fetal bovine serum (FBS, HyClone); Equipment: Microplate reader (BioTek Synergy H1), CO2 incubator (Thermo 371).

[0043] 1.2 Experimental methods 1.2.1 DPPH free radical scavenging rate Sample treatment: Dissolve each component in PBS (pH 7.4) and dilute it in gradient (0.1-100 μg / mL); Detection conditions: Add 0.1 mM DPPH ethanol solution and react in the dark for 30 min; The detection wavelength is 517 nm, and the IC50 (half inhibitory concentration) is calculated.

[0044] 1.2.2 HepG2 cell oxidative damage model Cell culture: HepG2 cells were inoculated into 96-well plates (1×10 4 / hole), cultured at 37°C and 5% CO2 for 24 h; Injury induction: Add 200 μM H2O2 and act for 4 h; Intervention treatment: Pre-incubate the sample (10 μg / mL) for 24 h; Cell viability detection: Incubate with CCK-8 reagent (Dojindo) for 2 h, and detect the absorbance at 450 nm.

[0045] 1.3 Data analysis Statistical method: One-way analysis of variance (ANOVA), Tukey's post hoc test, data are expressed as mean ± standard deviation (n = 6); Software: GraphPad Prism 9.0.

[0046] 1.4 Experimental results (see Figure 10 ) The antioxidant capacity and cell protection effect of the composition of Example 1 are superior to single components or commercial products, demonstrating the synergistic effect brought by nano-lecithin delivery + black pepper absorption promotion.

[0047] Experiment 2: Alcoholic liver injury animal model Objective: To compare the liver protection effects of the formula of Example 1 and conventional liver protection formulas.

[0048] 2.1 Experimental design Animals: SD rats (male, 180 - 220 g), purchased from Beijing Vital River, license number SCXK (Jing) 2020 - 0006; Grouping (n = 10): Normal group: Conventional diet + normal saline; Model group: Intragastric administration of ethanol (5 g / kg / d, 56% vol); Control formula group: Model + Phyllanthus niruri extract (200 mg / kg / d); Example 1 group: Model + the formula of Example 1 (500 mg / kg / d).

[0049] Duration: Continuously intervene for 4 weeks, and take blood and liver tissues after fasting for 12 h.

[0050] 2.2 Detection indexes Serum ALT / AST: Automatic biochemical analyzer (Hitachi 7080); Liver tissue MDA / SOD: Kits (Nanjing Jiancheng, A003 - 1 / A001 - 3); Pathological sections: HE staining (Leica RM2235 microtome).

[0051] 2.3 Statistical method The two-tailed t-test was used, and the data were expressed as mean ± SEM.

[0052] 2.4 Experimental results (see Figure 11 ) In the high-dose group of the present invention, the reduction of ALT / AST was 71.9% / 69.5%, which was significantly better than that of the control formula group (p < 0.001), and the MDA level decreased by 76.8%, demonstrating the synergistic regulatory effect of the combination of cordyceps militaris adenosine + selenium-enriched yeast + magnesium ascorbyl phosphate on the alcohol metabolism pathway (CYP2E1 / ADH).

[0053] In the formula of Example 1, the combination of magnesium ascorbyl phosphate and selenium-enriched yeast is the key synergistic component for achieving efficient liver protection, and they play a role through the following mechanisms: The trace element selenium provided by selenium-enriched yeast is the core coenzyme of glutathione peroxidase (GSH-Px), which can directly enhance the activity of liver antioxidant enzymes; As a stable derivative of vitamin C, magnesium ascorbyl phosphate can regenerate glutathione (GSH) and enhance the activity of superoxide dismutase (SOD). The two together with the flavonoid components in the extract of Penthorum chinense Pursh form a three-level protection system of "free radical scavenging - enzyme activity enhancement - oxidative stress inhibition" (see the DPPH scavenging rate in Experiment 1 and the SOD activity data in Experiment 2).

[0054] Based on Experiment 2, two additional control groups were set up: Selenium-enriched yeast-deficient group: Remove "1-3 parts of selenium-enriched yeast" from the formula, and keep other ingredients and dosages unchanged; Magnesium ascorbyl phosphate-deficient group: Remove "2-5 parts of magnesium ascorbyl phosphate" from the formula, and keep other ingredients and dosages unchanged.

[0055] Results of the control experiment (see Figure 12 )

[0056] Demonstration of the necessity of ingredients: After the absence of selenium-enriched yeast or magnesium ascorbyl phosphate, the reduction rates of ALT / AST decreased by 10.7% - 12.1% respectively, which were significantly lower than those of the present invention group (p < 0.01), proving that the two are core synergistic components, and the lack of any one of them will destroy the synergistic promotion effect of antioxidant enzyme activity.

[0057] The changes in SOD activity and MDA level further indicated that the two form an inseparable liver protection system with the extract of Penthorum chinense Pursh by enhancing the body's antioxidant capacity and reducing lipid peroxidation products.

[0058] Experiment 3: Verification of improved bioavailability Objective: To verify the synergistic effect of nano-lecithin and black pepper extract on the absorption of flavonoid components.

[0059] 3.1 HPLC Detection Conditions Instrument: Agilent 1260 Infinity II; Chromatographic column: ZORBAX SB-C18 (4.6×250 mm, 5 μm); Mobile phase: Acetonitrile: 0.1% phosphoric acid water = 45:55 (v / v); Flow rate: 1.0 mL / min; Detection wavelength: 370 nm (quercetin); Column temperature: 30 °C; Injection volume: 20 μL.

[0060] 3.2 Subject Protocol Population: Healthy volunteers (n = 12, 6 males and 6 females), signed informed consent forms; Drug administration: Single oral administration of the traditional formula or the formula of the present invention containing 50 mg of quercetin; Blood sampling points: 0 h, 0.5 h, 1 h, 2 h, 4 h, 6 h, 8 h, 24 h; Blood sample treatment: Heparin anticoagulation, centrifugation (3000 rpm, 10 min) to obtain plasma, stored at -80 °C.

[0061] 3.3 Pharmacokinetic Analysis Standard curve: Quercetin concentration 0.1 - 100 ng / mL (R² = 0.9993); Extraction recovery rate: 85.2% - 92.7%; Data fitting: Non-compartmental model (WinNonlin 8.1).

[0062] 3.4 Experimental Results (see Figure 13 ) The bioavailability (AUC) of quercetin in the group of the present invention increased by 186%, and the peak time was shortened by 28%, proving the synergistic effect of nano-lecithin and black pepper extract on the absorption of flavonoid components.

[0063] Experiment 4: Human Diet Intervention Trial Subjects: 60 patients with alcoholic fatty liver, randomly divided into a control group (placebo) and an experimental group (formula of Example 1, 3 g / d), and the trial duration was 12 weeks.

[0064] Experimental Results (see Figure 14 ) Conclusion: The formula of the present invention achieves the synergistic effects of liver injury repair, fat metabolism regulation, and anti-fatigue.

[0065] Supplement to Experiment 4: Influence of the Whole Ingredient System on the Human Diet Intervention Effect Supplementary analysis: Influence of the absence of key ingredients on the fatigue index In the human feeding experiment, an additional "lack of Agaricus blazei Murill β-glucan + Cordyceps militaris adenosine extract group" (removing these two components while keeping other components unchanged) was set up. The results showed that: The improvement rate of the fatigue index in the experimental group (with all components) was 3.6%; The improvement rate of the fatigue index in the lack of Agaricus blazei Murill β-glucan + Cordyceps militaris adenosine group was only 2.2% (p<0.05), proving that these two components are indispensable for the "anti-fatigue" effect by regulating the adenosine metabolic pathway and enhancing mitochondrial function.

[0066] Experiments 1-4 illustrate that Sample size and replication: In the animal experiment, n = 10 met the statistical power (Power>0.8), and in the cell experiment, n = 6 was replicated; Positive control selection: Commercially available liver-protecting tablets (silybin) were used as the gold standard control; Clinical relevance: The human trial dose was converted according to body weight (3-5 g per day for a 70-kg adult), which was within the safe range; Compliance of detection methods: The HPLC conditions referred to the method for determining the quercetin content in the Chinese Pharmacopoeia 2020 Edition.

[0067] Example 2: A solid beverage of Penthorum chinense Pursh consists of the following materials: 33 parts of Penthorum chinense Pursh extract; 16 parts of kudzu root powder; 11 parts of wolfberry polysaccharide concentrate; 12 parts of seabuckthorn fruit powder; 6 parts of tea polyphenol microcapsules; 6 parts of Agaricus blazei Murill β-glucan; 3 parts of Cordyceps militaris adenosine extract; 2 parts of mogroside; 4 parts of nanoscale lecithin; 2 parts of selenium-enriched yeast; 3 parts of magnesium ascorbyl phosphate; 2 parts of black pepper extract.

[0068] The difference between this Example 2 and Example 1 is that, referring to Figure 15 and Figure 16 , it is an optimized formula designed for people with mild liver injury or for daily health care needs. By adjusting the ratio of Penthorum chinense Pursh extract to excipients, the taste and economy are optimized while ensuring the liver-protecting effect.

[0069] In Experiment 3 of Example 1, a sub-item was added to supplement the bioavailability data (see Figure 15 ).

[0070] The bioavailability (AUC) of quercetin in Example 2 was increased by 159% compared with the traditional formula. Although it was slightly lower than that in Example 1, it was still significantly better than the traditional formula. The Tmax (peak time) and t1 / 2 (half-life) were close to those in Example 1, indicating that the ratio of the core delivery system (nanolecithin + black pepper extract) of 3 - 8 parts / 0.5 - 2 parts could achieve rapid absorption and sustained release.

[0071] Dose-dependent verification of liver protection effect Animal experiment data (see Figure 16 ) The decline rate of ALT / AST in Example 2 was slightly lower than that in Example 1, but it was still 1.86 times that of the control formula group. The low-dose formula was suitable for the prevention scenario. The SOD activity was increased by 74% compared with the control formula group, verifying that selenium-enriched yeast and magnesium ascorbyl phosphate could still effectively activate antioxidant enzymes at a medium ratio.

[0072] In Example 2, by reducing the proportion of Penthorum chinense Pursh extract and increasing the proportion of seabuckthorn fruit powder and wolfberry polysaccharide, the following technical advantages were achieved: Taste optimization: The acidic components of seabuckthorn fruit powder and mogroside synergistically regulated the sweetness and acidity, and the palatability was increased by 30% (verified by the sensory evaluation of 50 people). Intestinal barrier protection: Agaricus blazei Murill β-glucan and wolfberry polysaccharide formed a mucosal protector, which, combined with the liposomal delivery of nanolecithin, further improved the intestinal absorption efficiency of flavonoid components (2.1 times higher than that of single Penthorum chinense Pursh extract). Metabolic synergy: The ratio of Cordyceps militaris adenosine extract and black pepper extract was optimized to specifically regulate the activity of alcohol dehydrogenase (ADH) and accelerate the clearance of acetaldehyde, the metabolite of alcohol, which was suitable for the preventive liver protection of people with frequent social activities.

[0073] Example 3: Refer to Figures 1 - 7, A processing device for Patrinia scabra solid beverage, comprising: a processing barrel 100; a driving rod 400 coaxially penetrating through the top and bottom of the processing barrel 100, and the driving rod 400 is arranged to rotate within the processing barrel 100; a crushing structure 600 installed on the driving rod 400, the crushing structure 600 includes two moving knives 602 connected to the driving rod 400, and the two moving knives 602 generate radial shearing force as they rotate with the driving rod 400; an extrusion assembly including an extrusion plate 200 and a separation plate 300, the extrusion plate 200 and the separation plate 300 are arranged on the driving rod 400, the crushing structure 600 is arranged between the extrusion plate 200 and the separation plate 300, and the separation plate 300 is provided with separation holes, and the extrusion plate 200 and the separation plate 300 are arranged to be able to approach or move away from each other simultaneously, for extruding the Patrinia scabra material and separating the juice; a driving mechanism installed within the processing barrel 100, the driving mechanism is connected to the extrusion plate 200 and the separation plate 300, and is used to drive the extrusion plate 200 and the separation plate 300 to move.

[0074] By driving the two moving knives 602 to rotate at a high speed within the processing barrel 100 by the driving rod 400, the Patrinia scabra material between the extrusion plate 200 and the separation plate 300 can be crushed. A cover plate is provided on the extrusion plate 200, and by opening the cover plate, the Patrinia scabra material can be directly put into the crushing area. During the crushing process, the driving mechanism can be used to drive the extrusion plate 200 and the separation plate 300 to approach each other, applying pressure to the Patrinia scabra material, so that the juice in the Patrinia scabra is extruded and separated from the separation plate 300 to the bottom area of the processing barrel 100. Moreover, the driving rod 400 has a movable contact with the extrusion plate 200 and the separation plate 300. During the rotation of the driving rod 400, the movement of the extrusion plate 200 and the separation plate 300 will not be affected.

[0075] The driving rod 400 includes: a moving groove 401 opened on the surface of the driving rod 400; a slider 402 connected within the moving groove 401, and the slider 402 is connected to the moving knife 602; a cavity 404 opened on the driving rod 400, a collection port is opened on the inner wall of the cavity 404, and an opening is provided at the bottom of the cavity 404; a piston 405 installed within the cavity 404; a connecting rope 407, one end is installed on the slider 402, the other end penetrates through the moving groove 401 and extends into the cavity 404, and is connected to the piston 405; a first one-way valve 408 installed within the collection port, and the liquid outlet of the first one-way valve 408 faces the cavity 404; a second one-way valve 409 installed at the bottom opening of the cavity 404, and the liquid inlet of the second one-way valve 409 faces the cavity 404; an elastic member 406, one end is installed on the inner wall of the cavity 404, and the other end is installed on the piston 405.

[0076] The moving knife 602 is connected to the moving groove 401 on the surface of the driving rod 400 through the slider 402, so that the moving knife 602 can move along the axial direction of the driving rod 400 and can also rotate with the radial rotation of the driving rod 400. The moving directions of the two are perpendicular to each other. While the moving knife 602 can move on the driving rod 400, it does not affect the driving rod 400 to drive the moving knife 602 to rotate. The moving power of the moving knife 602 is pushed by the pressing plate 200 or the separating plate 300, that is, when the pressing plate 200 or the separating plate 300 moves on the driving rod 400, it can push the moving knife 602 to move, and the moving knife 602 drives the slider 402 to linearly slide in the moving groove 401. In addition, a gasket is provided between the moving knife 602 and the pressing plate 200 or the separating plate 300, and this gasket can improve the smoothness of the rotation of the moving knife 602 and avoid friction between the moving knife 602 and the pressing plate 200 or the separating plate 300 directly. By using the movement of the moving knife 602 and the slider 402, the slider 402 can pull the connecting rope 407 during the moving process, convert the movement of the slider 402 into the movement of the piston 405. The liquid outlet of the first one-way valve 408 faces the inner cavity 404 to ensure that the juice can only flow into the inner cavity 404 unidirectionally; the liquid inlet of the second one-way valve 409 faces the inner cavity 404 to ensure that the juice can be smoothly discharged from the inner cavity 404; the elastic member 406 is a spring or can also be an elastic block. The elastic member 406 provides elastic force for the reset of the piston 405. When the piston 405 moves away from the collection port, a negative pressure is formed in the inner cavity 404, and the juice generated during the pulverization process of the Senecio scandens Buch.-Ham. enters the inner cavity 404 through the collection port and the first one-way valve 408. After the separating plate 300 is reset, the elastic member 406 drives the piston 405 to reset. The piston 405 pulls the connecting rope 407 and pulls the slider 402 and the moving knife 602 through the connecting rope 407, so that the moving knife 602 is also reset. When the piston 405 moves towards the collection port, the juice is squeezed by the piston 405 and is discharged from the bottom opening of the inner cavity 404 through the second one-way valve 409, completing the juice separation.

[0077] The slider 402 includes: an inclined block 403, which is installed at the bottom of the slider 402, and the inclined block 403 is arranged in the moving groove 401.

[0078] The above-mentioned inclined block 403 is arranged on the slider 402. When the slider 402 moves in the moving groove 401, the inclined block 403 also moves in the moving groove 401 together with the slider 402. The inclined block 403 can use the inclined surface to extrude or push out the materials accumulated in the moving groove 401 to ensure the smooth movement of the slider 402.

[0079] The driving mechanism includes: a first power source 101, which is installed on the top wall of the processing barrel 100, and the power shaft of the first power source 101 is connected to the pressing plate 200; a second power source 102, which is installed at the bottom of the processing barrel 100, and the power shaft of the second power source 102 is connected to the separating plate 300.

[0080] The driving mechanism includes various implementation methods. In the third embodiment, the extrusion plate 200 is driven by the first power source 101 and moves axially within the processing barrel 100. The separation plate 300 is driven by the second power source 102 and moves axially within the processing barrel 100. Both the first power source 101 and the second power source 102 use hydraulic cylinders, or pneumatic cylinders can also be used. The extrusion plate 200 and the separation plate 300 can move towards the middle simultaneously, or the movement of the extrusion plate 200 can be controlled independently, or the separation plate 300 can be controlled to move towards the extrusion plate 200 independently.

[0081] It further includes: a fourth power source 500, installed within the processing barrel 100; a first transmission wheel 501, installed on the power shaft of the fourth power source 500; a second transmission wheel 502, installed on the driving rod 400, and the second transmission wheel 502 is connected to the first transmission wheel 501 through a belt.

[0082] The above-mentioned fourth power source 500 serves as the driving source of the driving rod 400. It can drive the belt to move through the first transmission wheel 501, and then the belt drives the second transmission wheel 502 and the driving rod 400 to rotate. The driving rod 400 can drive the moving knife 602 and the fixed knife 601 to rotate.

[0083] The crushing structure 600 further includes: a fixed knife 601, installed on the driving rod 400, and the fixed knife 601 is located between the two moving knives 602.

[0084] The two moving knives 602 are connected to the driving rod 400 and generate a radial shearing force during rotation, which is used to crush the swertia mileensis materials. The fixed knife 601 is located between the two moving knives 602, and the moving knife 602 cooperates with the fixed knife 601 to form a more efficient crushing effect and improve the crushing degree of the materials.

[0085] Embodiment 4: The difference between this embodiment 4 and embodiment 3 is that, referring to Figure 8 and Figure 9 , the driving mechanism includes: a third power source 103, installed on the processing barrel 100; a first connecting rod 105, with one end installed on the extrusion plate 200 and the other end provided with a telescopic groove; a second connecting rod 106, with one end installed on the separation plate 300 and the other end connected in the telescopic groove; a lead screw 104, with one end connected to the power shaft of the third power source 103 and the other end passing through the extrusion plate 200 and threadedly connected to the second connecting rod 106.

[0086] The driving mechanism is another implementation method. By driving the lead screw 104 to rotate through the third power source 103, the extrusion plate 200 and the separation plate 300 move relatively to achieve the extrusion function. The third power source 103 uses a servo motor, or a stepper motor can also be used.

[0087] During use, open the cover plate on the extrusion plate 200, evenly put an appropriate amount of Herba Patriniae materials into the crushing area between the extrusion plate 200 and the separation plate 300, and close the cover plate after putting to prevent the materials from splashing during processing. Start the fourth power source 500. The power shaft of the fourth power source 500 drives the first transmission wheel 501 to rotate. Through belt transmission, the second transmission wheel 502 installed on the driving rod 400 rotates, and then drives the driving rod 400 to rotate at a high speed in the processing barrel 100. The driving rod 400 drives the two moving knives 602 and the fixed knife 601 to rotate together. The two moving knives 602 generate radial shear force with the radial rotation of the driving rod 400 and cooperate with the fixed knife 601 located between the two moving knives 602 to efficiently crush the Herba Patriniae materials in the crushing area. During the crushing process, since the moving knife 602 is connected to the moving groove 401 on the surface of the driving rod 400 through the slider 402, while the moving knife 602 rotates with the driving rod 400, if it is pushed by the extrusion plate 200 or the separation plate 300, it can also move axially along the driving rod 400.

[0088] If it is necessary to extrude the materials at the same time, start the first power source 101 and the second power source 102. The power shaft of the first power source 101 pushes the extrusion plate 200 to move axially downward in the processing barrel 100, and the power shaft of the second power source 102 pushes the separation plate 300 to move axially upward in the processing barrel 100. The extrusion plate 200 and the separation plate 300 move towards the middle at the same time to apply pressure to the crushed Herba Patriniae materials. If only the movement of the extrusion plate 200 or the separation plate 300 needs to be controlled separately, start the corresponding power source separately. Start the first power source 101 alone to make the extrusion plate 200 move downward to extrude the materials; or start the second power source 102 alone to make the separation plate 300 move upward to extrude the materials.

[0089] As the extrusion plate 200 and the separation plate 300 get closer and closer, the extrusion force on the Herba Patriniae materials gradually increases, and the juice in the Herba Patriniae is fully extruded. The extruded juice passes through the separation holes opened on the separation plate 300 and is separated from the separation plate 300 to the bottom area of the processing barrel 100 to complete the separation of the juice and the solid residue. When the extrusion and juice separation processes are over, control the driving mechanism to reset the extrusion plate 200 and the separation plate 300.

[0090] During the movement of the extrusion plate 200 and the separation plate 300, the extrusion plate 200 or the separation plate 300 pushes the moving knife 602 to move. The moving knife 602 drives the slider 402 to linearly slide in the moving groove 401 on the surface of the driving rod 400. When the inclined block 403 at the bottom of the slider 402 moves in the moving groove 401, the material accumulated in the moving groove 401 is extruded or pushed out by using the inclined plane to ensure the smooth movement of the slider 402. At the same time, the slider 402 pulls the connecting rope 407 during the movement, and the connecting rope 407 drives the piston 405 to move in the inner cavity 404 of the driving rod 400. When the piston 405 moves away from the collection port, a negative pressure is formed in the inner cavity 404, and the juice generated during the pulverization process of the herba hyperici attenuati passes through the collection port and enters the inner cavity 404 through the first one-way valve 408; when the piston 405 moves towards the collection port, the juice is extruded by the piston 405 and discharged from the bottom opening of the inner cavity 404 through the second one-way valve 409, realizing the collection of the juice.

[0091] In summary, compared with the prior art, the following beneficial effects are achieved: In this solution, the extrusion plate 200 and the separation plate 300 approach and extrude synchronously, and cooperate with the dynamic crushing of the moving knife 602, so that under the dual actions of continuous shearing and extrusion, the juice is quickly separated out and discharged through the separation holes, reducing the adhesion of the material to the inner wall of the equipment. The real-time juice separation reduces the viscosity of the material and reduces the load on the moving knife 602.

[0092] When the two moving knives 602 rotate at high speed, they are driven by the extrusion plate 200 to move closer to the middle, forming a combined force of rotational shearing and axial compression. When the distance between the moving knives 602 is large, the large pieces of stems and leaves can be cut off by high-speed rotation. When the extrusion plate 200 pushes the distance between the moving knives 602 to shrink, the material is further sheared to completely destroy the cell wall.

[0093] Through the piston 405 and one-way valve built in the driving rod 400, the movement of the moving knife 602 is converted into the power for juice collection. When the slider 402 moves, it pulls the piston 405 to form a negative pressure, and the juice is sucked in through the first one-way valve 408; when reset, the piston 405 extrudes the juice and discharges it through the second one-way valve 409, realizing closed automatic collection and avoiding the residue of juice to breed bacteria or block the equipment.

[0094] By integrating the functions of pulverization, extrusion, and juice separation in the processing barrel 100, the material transfer equipment and manual operations are reduced, and the production capacity is improved.

[0095] Accordingly, while the present invention has been described herein with reference to its specific embodiments, modifications, various changes and substitutions are also within the above disclosure, and it should be understood that in some cases, some features of the present invention will be employed without corresponding use of other features, without departing from the scope and spirit of the claimed invention. Therefore, many modifications may be made to adapt a particular environment or material to the essential scope and spirit of the present invention. The present invention is not intended to be limited to the specific terms used in the following claims and / or the specific embodiments disclosed as the best mode contemplated for carrying out the present invention, but the present invention will include any and all embodiments and equivalents falling within the scope of the appended claims. Accordingly, the scope of the present invention will be determined solely by the appended claims.

Claims

1. A solid beverage of Herba Chrysanthemi Indici, characterized in that: It is composed of the following materials: 30-60 parts of Herba Lycopodiellae extract; 15-25 parts of kudzu root powder; 10-15 parts of wolfberry polysaccharide concentrate; 10-15 parts of sea buckthorn fruit powder; 5-8 portions of tea polyphenol microcapsules; 5-10 parts of Agaricus blazei beta-glucan; 2-6 parts of Cordyceps militaris adenosine extract; 1-5 parts of mogroside; 3-8 parts of nano-lecithin; 1-3 parts of selenium-enriched yeast; 2-5 parts of magnesium ascorbyl phosphate; Black pepper extract 0.5-2 parts.

2. A solid beverage processing equipment for the herb of Ganhuangcao as claimed in claim 1, characterized in that: include: Processing barrel (100); A driving rod (400) coaxially passes through the top and bottom of the processing barrel (100), and the driving rod (400) is configured to rotate within the processing barrel (100); The crushing structure (600) is mounted on the driving rod (400). The crushing structure (600) includes two moving knives (602) connected to the driving rod (400). The two moving knives (602) rotate with the driving rod (400) to shear and crush the material. The extrusion assembly comprises an extrusion plate (200) and a separation plate (300), wherein the extrusion plate (200) and the separation plate (300) are sleeved on a driving rod (400), a crushing structure (600) is arranged between the extrusion plate (200) and the separation plate (300), a separation hole is provided on the separation plate (300), and the extrusion plate (200) and the separation plate (300) are arranged to be able to approach or move away from each other at the same time, so as to extrude the yellow grass material and separate the juice; The driving mechanism is installed in the processing barrel (100), and the driving mechanism is connected to the extrusion plate (200) and the separation plate (300), and is used to drive the extrusion plate (200) and the separation plate (300) to move.

3. The solid beverage processing equipment of the Herba Chrysanthemi Indici according to claim 2 is characterized in that: The driving rod (400) comprises: A movable groove (401) is formed on the surface of the driving rod (400); The slider (402) is connected in the movable groove (401), and the slider (402) is connected to the movable knife (602).

4. The solid beverage processing equipment of the Herba Chrysanthemi Indici according to claim 3 is characterized in that: The driving rod (400) further comprises: An inner cavity (404) is provided on the driving rod (400), a collecting port is provided on the inner wall of the inner cavity (404), and an opening is provided at the bottom of the inner cavity (404); A piston (405) is installed in the inner cavity (404); A connecting rope (407) has one end mounted on the slider (402) and the other end passing through the movable groove (401) and extending into the inner cavity (404) and connected to the piston (405).

5. The solid beverage processing equipment of Ganhuangcao according to claim 4 is characterized in that: The driving rod (400) further comprises: A first one-way valve (408) is installed in the collecting port, and a liquid outlet of the first one-way valve (408) faces the inner cavity (404); A second one-way valve (409) is installed at the bottom opening of the inner cavity (404), and the liquid inlet of the second one-way valve (409) faces the inner cavity (404); The elastic member (406) has one end mounted on the inner wall of the inner cavity (404) and the other end mounted on the piston (405).

6. The solid beverage processing equipment of Ganhuangcao according to claim 3 is characterized in that: The slider (402) comprises: The inclined block (403) is installed at the bottom of the sliding block (402), and the inclined block (403) is arranged in the moving groove (401).

7. The solid beverage processing equipment of the Herba Chrysanthemi Indici according to claim 2, characterized in that: The driving mechanism comprises: A first power source (101) is mounted on the top wall of the processing barrel (100), and a power shaft of the first power source (101) is connected to the extrusion plate (200); The second power source (102) is installed at the bottom of the processing barrel (100), and the power shaft of the second power source (102) is connected to the separation plate (300).

8. The solid beverage processing equipment of Ganhuangcao according to claim 2 is characterized in that: Also includes: A fourth power source (500) is installed in the processing barrel (100); A first transmission wheel (501) is mounted on a power shaft of a fourth power source (500); The second transmission wheel (502) is mounted on the driving rod (400), and the second transmission wheel (502) is connected to the first transmission wheel (501) via a belt.

9. The solid beverage processing equipment of Ganhuangcao according to claim 2, characterized in that: The pulverizing structure (600) further includes: The fixed knife (601) is mounted on the driving rod (400), and the fixed knife (601) is located between the two movable knives (602).

10. The solid beverage processing equipment of Ganhuangcao according to claim 2, characterized in that: The driving mechanism comprises: A third power source (103) is installed on the processing barrel (100); A first connecting rod (105), one end of which is mounted on the extrusion plate (200) and the other end of which is provided with a telescopic slot; A second connecting rod (106), one end of which is mounted on the separation plate (300) and the other end of which is connected to the telescopic groove; A screw rod (104) has one end connected to the power shaft of the third power source (103), and the other end passes through the extrusion plate (200) and is threadedly connected to the second connecting rod (106).

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