Traditional Chinese medicine composition for treating chronic diarrhea and application thereof

Abstract

Aiming at etiology and pathogenesis of chronic diarrhea caused by deficiency-cold in spleen and stomach, the traditional Chinese medicine composition takes hairyvein agrimony, rhizoma acori graminei and rhizoma atractylodis as monarch drugs and takes dried ginger, fructus psoraleae, schisandra chinensis, myristica fragrans, cinnamon, agastache rugosus and Chinese yam as ministerial drugs; according to the traditional Chinese medicine composition, rhizoma corydalis, radix paeoniae alba, scorched hawthorn fruit, pericarpium granati, plantain herb, red halloysite, fructus chebulae and radix saposhnikoviae are taken as adjuvant drugs, liquorice is taken as a conductant drug, all the drugs are compatible, the purposes of invigorating spleen, replenishing qi, eliminating dampness, promoting diuresis, supporting healthy qi and smoothing middle-jiao qi movement can be achieved, the purpose of stopping diarrhea can be achieved, and the chronic diarrhea caused by deficiency-cold in the spleen and the stomach can be effectively treated.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating chronic diarrhea and its application. Background Art

[0002] Chronic diarrheal refers to a digestive system disease with the number of bowel movements ≥ 3 times / d, or the total fecal volume > 200 g / d, where the water content in the feces > 85%, and the course of the disease exceeds 4 weeks. Chronic diarrhea is a common clinical symptom, manifested as an increase in the number of stools, loose stools, and even mucus or purulent and bloody stools, lasting for more than two months. The characteristics of diarrhea caused by small intestine lesions are abdominal discomfort, mostly around the umbilicus, and aggravated after meals or before defecation, without tenesmus, a large amount of stools, light color, and the number of stools can be more or less; the characteristics of diarrhea caused by colon lesions are abdominal discomfort, located on both sides or lower abdomen of the abdomen, often relieved or reduced after defecation, frequent and urgent defecation, a small amount of feces, often containing blood and mucus; those caused by rectal lesions are often accompanied by tenesmus. Western medicine mostly adopts symptomatic supportive treatments such as antidiarrheal, electrolyte supplementation, and anti-infection, or improves diarrhea symptoms through treatment methods such as enhancing immunity and regulating intestinal flora, but lacks long-term effective treatment methods for controlling diarrhea. In traditional Chinese medicine, chronic diarrhea belongs to the category of "diarrhea". This disease was first recorded in "Huangdi Neijing" and has relevant descriptions such as "duck-like loose stools", "undigested diarrhea", "loose diarrhea", "profuse diarrhea", "pouring diarrhea", "loose stools", and "diarrhea with fluid pouring". The efficacy of traditional Chinese medicine treatment is relatively mild and the side effects are small. However, due to the very complex etiology of chronic diarrhea, traditional Chinese medicine is not targeted enough, often affecting the curative effect. Summary of the Invention

[0003] Therefore, based on the above background, the present invention provides a traditional Chinese medicine composition for treating chronic diarrhea, which treats chronic diarrhea of the spleen and stomach deficiency-cold syndrome type with remarkable curative effect.

[0004] The technical solution of the present invention is as follows:

[0005] A traditional Chinese medicine composition for treating chronic diarrhea, which is composed of the following raw materials by weight:

[0006] 8 - 20 parts of Agrimonia pilosa Ledeb., 5 - 25 parts of Acorus tatarinowii Schott, 5 - 20 parts of Atractylodes lancea (Thunb.) DC., 5 - 20 parts of Drynaria fortunei (Kunze) J. Sm., 2 - 10 parts of Psoralea corylifolia L., 2 - 10 parts of Schisandra chinensis (Turcz.) Baill., 5 - 20 parts of Myristica fragrans Houtt., 1 - 5 parts of Cinnamomum cassia Presl, 5 - 20 parts of Pogostemon cablin (Blanco) Benth., 2 - 10 parts of Dioscorea opposita Thunb., 5 - 20 parts of Corydalis yanhusuo W. T. Wang, 8 - 20 parts of Paeonia lactiflora Pall., 8 - 20 parts of Fructus Crataegi Pyrolae, 8 - 20 parts of Granatum pericarpium, 2 - 10 parts of Plantago asiatica L., 2 - 10 parts of Halloysitum rubrum, 2 - 10 parts of Terminalia chebula Retz., 2 - 10 parts of Saposhnikovia divaricata (Turcz.) Schischk., 2 - 10 parts of Radix Glycyrrhizae Preparata.

[0007] Preferably, it is composed of the following raw materials by weight:

[0008] 10 parts of Agrimonia pilosa Ledeb., 15 parts of Acorus tatarinowii Schott, 10 parts of Atractylodes lancea (Thunb.) DC., 10 parts of Dry Ginger, 5 parts of Psoralea corylifolia L., 5 parts of Schisandra chinensis (Turcz.) Baill., 10 parts of Myristica fragrans Houtt., 3 parts of Cinnamomum cassia Presl, 10 parts of Pogostemon cablin (Blanco) Benth., 5 parts of Dioscorea opposita Thunb., 10 parts of Corydalis yanhusuo W. T. Wang, 15 parts of Paeonia lactiflora Pall., 10 parts of Hawthorn Fruit (processed), 10 parts of Granatum Bark, 5 parts of Plantago asiatica L., 5 parts of Halloysitum Rubrum, 5 parts of Terminalia chebula Retz., 5 parts of Saposhnikovia divaricata (Turcz.) Schischk., 5 parts of Honey-Fried Licorice Root.

[0009] Preferably, it is composed of raw materials with the following weights:

[0010] 8 parts of Agrimonia pilosa Ledeb., 10 parts of Acorus tatarinowii Schott, 10 parts of Atractylodes lancea (Thunb.) DC., 5 parts of Dry Ginger, 5 parts of Psoralea corylifolia L., 5 parts of Schisandra chinensis (Turcz.) Baill., 5 parts of Myristica fragrans Houtt., 3 parts of Cinnamomum cassia Presl, 10 parts of Pogostemon cablin (Blanco) Benth., 5 parts of Dioscorea opposita Thunb., 5 parts of Corydalis yanhusuo W. T. Wang, 10 parts of Paeonia lactiflora Pall., 10 parts of Hawthorn Fruit (processed), 10 parts of Granatum Bark, 2 parts of Plantago asiatica L., 5 parts of Halloysitum Rubrum, 5 parts of Terminalia chebula Retz., 5 parts of Saposhnikovia divaricata (Turcz.) Schischk., 5 parts of Honey-Fried Licorice Root.

[0011] Preferably, it is composed of raw materials with the following weights:

[0012] 20 parts of Agrimonia pilosa Ledeb., 20 parts of Acorus tatarinowii Schott, 5 parts of Atractylodes lancea (Thunb.) DC., 15 parts of Dry Ginger, 5 parts of Psoralea corylifolia L., 5 parts of Schisandra chinensis (Turcz.) Baill., 15 parts of Myristica fragrans Houtt., 5 parts of Cinnamomum cassia Presl, 10 parts of Pogostemon cablin (Blanco) Benth., 10 parts of Dioscorea opposita Thunb., 10 parts of Corydalis yanhusuo W. T. Wang, 15 parts of Paeonia lactiflora Pall., 15 parts of Hawthorn Fruit (processed), 10 parts of Granatum Bark, 2 parts of Plantago asiatica L., 5 parts of Halloysitum Rubrum, 5 parts of Terminalia chebula Retz., 5 parts of Saposhnikovia divaricata (Turcz.) Schischk., 5 parts of Honey-Fried Licorice Root.

[0013] Based on the same inventive concept, the present invention applies the above-mentioned traditional Chinese medicine composition for treating chronic diarrhea to the preparation of drugs for chronic diarrhea.

[0014] Furthermore, the chronic diarrhea is chronic diarrhea of the spleen-stomach deficiency-cold syndrome type.

[0015] Furthermore, the dosage form of the drug is an oral dosage form.

[0016] Furthermore, the oral dosage form includes powder, granule, capsule, tablet, pill and solution.

[0017] Furthermore, the drug uses the extract or extract prepared from the above-mentioned traditional Chinese medicine composition for treating chronic diarrhea as the active ingredient.

[0018] The pharmacology of each raw material in the traditional Chinese medicine composition of the present invention is as follows:

[0019] Agrimonia pilosa Ledeb. is bitter in taste and neutral in nature, and belongs to the heart and liver meridians. It is astringent and convergent, neutral and not biased, and enters the lung, liver and spleen meridians. It not only arrests bleeding with astringency, supplements deficiency, but also detoxifies and stops dysentery, arrests malaria, and also kills insects, relieves cough and has anti-cancer effects. Its hemostatic power is strong and reliable, and it is suitable for all types of bleeding, whether cold, heat, deficiency or excess, and also treats chronic diarrhea and dysentery, malaria, sores, pudendal itching and leukorrhea, and exhaustion due to overwork. Arrest bleeding with astringency, arrest malaria, stop dysentery, detoxify, supplement deficiency.

[0020] Acorus calamus is pungent and bitter in taste, warm in nature, and enters the heart and stomach meridians. It can open the orifices and dissipate phlegm, wake up the mind and improve intelligence, and remove dampness and stimulate the appetite. It is pungent, dispersing, fragrant, bitter, dry, and warming, and enters the heart and stomach meridians. It is good at removing phlegm and dampness, opening the orifices and treating symptoms of phlegm and dampness blocking the heart orifices; it can also calm the mind and harmonize the stomach qi, and treat palpitations, insomnia, forgetfulness and trance caused by deficiency of heart qi, as well as dampness and turbidity blocking the middle and lockjaw dysentery.

[0021] Atractylodes lancea tastes pungent and bitter, and is warm in nature. It enters the spleen, stomach, and liver meridians. It dispels cold and strengthens the spleen, and dries dampness and promotes diuresis. It is bitter, dry, pungent, and dispersing, and aromatic and warming. It enters the spleen and stomach meridians, can dry dampness and strengthen the spleen, and is an essential medicine for treating dampness blocking the middle jiao syndrome, especially for those with cold and dampness blocking the spleen; it moves to the surface of the limbs, dispels cold and dampness, and eliminates numbness, and releases the exterior. It is commonly used to treat wind-cold-dampness arthralgia and superficial syndrome with dampness.

[0022] Dried ginger is pungent and hot in nature. It enters the spleen, stomach, kidney, heart, and lung meridians. It warms the middle and dispels cold, restores yang and dredges the meridians, and warms the lungs and dissolves fluid. It is pungent, hot, and dispersing. It enters the spleen and stomach meridians. It can dispel the cold evil of the spleen and stomach and help the yang of the spleen and stomach. It is an important medicine for warming the middle and dispelling cold. It is suitable for both real cold and false cold syndrome. It enters the heart meridian and can restore yang and dredge the meridians. It enters the lung meridian and can warm the lungs and dissolve fluid. It is often used to treat cough and asthma caused by cold fluid.

[0023] Psoralea corylifolia tastes pungent and bitter, is warm in nature, and enters the kidney and spleen meridians. It warms the kidney and strengthens yang, consolidates semen and reduces urine, promotes qi and relieves asthma, and warms the spleen and stops diarrhea. Psoralea corylifolia tastes bitter, pungent, warm, and dry, warms and nourishes, and is astringent, and enters the kidney and spleen meridians. It not only nourishes the kidney and strengthens yang, consolidates semen and reduces urine, promotes qi and relieves asthma, but also treats impotence due to kidney deficiency, spermatorrhea, and asthma due to kidney deficiency; it also warms the spleen and stops diarrhea, and is an essential medicine for diarrhea due to spleen and kidney yang deficiency.

[0024] Schisandra chinensis is sour and sweet, warm in nature, and enters the lung, heart, and kidney meridians. It has astringent and firming properties, replenishes qi and produces body fluid, and nourishes the kidney and calms the mind. It is sour, astringent, moist, warm and nourishing, and has both astringent and nourishing properties. It enters the lung, kidney, and heart meridians. It can astringe the lungs, relieve cough and asthma, nourish the kidneys, astringe the essence and stop diarrhea, produce body fluid, calm the mind and soothe the nerves, and consolidate the exterior, astringe and stop sweating. It has all five flavors, but only the sour one is better; although it is warm in nature, it is moist in nature; it has both astringent and nourishing properties, and it can save energy and provide support. It has a strong medicinal effect and is an important medicine for tonifying deficiency, strengthening, and astringing.

[0025] Nutmeg is pungent and warm in nature. It enters the spleen, stomach and large intestine meridians. It warms the middle and promotes qi circulation, astringes the intestines and stops diarrhea. It is warm and astringent, pungent and fragrant, and dispersing. It enters the spleen, stomach and large intestine meridians. It is good at warming the middle and astringing the intestines, and treats chronic diarrhea caused by yang deficiency; it can also warm the middle and promote qi circulation, and treat deficiency, cold, qi stagnation, and is a product that takes into account both the symptoms and the root cause.

[0026] Cinnamon is pungent and sweet in taste, very hot in nature, and enters the kidney, spleen, heart, and liver meridians. It warms the middle and dispels cold, regulates qi and relieves pain. It is pungent, sweet and hot, warms and nourishes, and disperses, with thick qi and pure yang. It enters the kidney meridian, slowly replenishes kidney yang and replenishes fire to help yang or guides fire back to the origin. It enters the liver, heart, and meridians, relieves cold and chronic cold, dispels cold and relieves pain, warms and dredges the meridians, and activates blood circulation and dissipates blood stasis. It is good at replenishing yang and eliminating yin, slowly replenishing kidney yang and guiding fire back to the origin, and is an important medicine for replenishing fire and helping yang; it also enters the blood, is good at warming and unblocking the meridians, and improves microcirculation. It is suitable for people with cold blood.

[0027] Agastache rugosa has a pungent taste, warm nature, and acts on the spleen, stomach, and lung meridians. It resolves dampness to awaken the spleen, dispels foulness and harmonizes the middle, relieves summer heat, and induces sweating. Its fragrance can assist the clear qi in the middle jiao, overcome dampness and dispel foulness. It has a mild and fragrant warmth, and is good at regulating the damp turbidity and phlegm in the middle jiao. It is used for symptoms such as dampness obstructing the spleen and stomach, fullness and distension in the epigastrium and abdomen, the initial stage of damp-warm syndrome, vomiting, diarrhea, summer dampness, fever and aversion to cold, aversion to cold and fever, fullness and oppression in the chest and epigastrium, etc.

[0028] Chinese yam has a sweet taste, neutral nature, and acts on the spleen, lung, and kidney. It supplements qi and nourishes yin, tonifies the spleen, lungs, and kidneys. It is used to treat poor appetite due to spleen deficiency, loose stools, excessive leucorrhea, cough due to lung deficiency, spermatorrhea due to kidney deficiency, leucorrhea, frequent urination, and consumptive thirst with deficiency heat.

[0029] Corydalis yanhusuo has a pungent and bitter taste, warm nature, and acts on the liver and spleen meridians. It promotes blood circulation, activates qi, and relieves pain. Its pungency disperses, bitterness purges, and warmth dredges. It enters the heart, liver, and spleen meridians. It is strong in promoting blood circulation, activating qi, and relieving pain. It can be used for pain due to blood stasis and qi stagnation, especially those with cold syndrome.

[0030] White peony root has a bitter and sour taste, slightly cold nature, and acts on the liver and spleen meridians. It nourishes blood and regulates menstruation, astringes yin and stops sweating, soothes the liver and relieves pain, and suppresses liver yang. It is used for symptoms such as sallow complexion due to blood deficiency, irregular menstruation, metrorrhagia and metrostaxis, spontaneous sweating, night sweating, pain in the hypochondrium and epigastrium, acute pain in the limbs, hyperactivity of liver yang, headache and dizziness, etc.

[0031] Fried Hawthorn can strengthen the spleen and promote digestion, promote digestion and remove stagnation, activate qi and disperse stasis, etc.

[0032] Pomegranate peel has a sour and astringent taste, warm nature, and acts on the large intestine meridian. It arrests diarrhea and stops bleeding. It is used for chronic diarrhea, chronic dysentery, hematochezia, rectal prolapse, metrorrhagia and metrostaxis, leucorrhea, and abdominal pain due to intestinal parasites.

[0033] Plantain herb has a sweet taste, cold nature, and acts on the liver, kidney, lung, and small intestine meridians. It clears heat and promotes diuresis, cools the blood, and detoxifies. It is mainly used for heat accumulation in the bladder, dysuria, turbid leukorrhea and vaginal discharge, summer dampness diarrhea and dysentery, epistaxis, hematuria, redness of the eyes due to liver heat, sore throat, and carbuncles and sores.

[0034] Halloysite has a sweet, sour, and astringent taste, warm nature, and acts on the large intestine and stomach meridians. It has the effects of arresting diarrhea, stopping bleeding, and promoting granulation and healing sores. It is commonly used for chronic diarrhea and dysentery, bleeding in the stool, metrorrhagia and metrostaxis, and leucorrhea; externally for non-healing sores and ulcers, and eczema with purulent discharge.

[0035] Terminalia chebula has a bitter, sour, and astringent taste, neutral nature, and acts on the lung and large intestine meridians. It arrests diarrhea and relieves cough, astringes the lung and relieves sore throat. Its bitterness can purge and descend, and its sourness and astringency can astringe. The bitterness is more than the sourness. It enters the lung and large intestine meridians. It is good at arresting diarrhea and reducing qi to relieve distension. It is suitable for those with chronic diarrhea and dysentery with cold syndrome and abdominal distension.

[0036] Fang Fang has a pungent and sweet flavor, is slightly warm in nature, and enters the bladder, liver, and spleen meridians. It dispels wind and relieves exterior symptoms, overcomes dampness and relieves pain, and stops spasms. It is pungent, slightly warm and dispersing, and is sweet and mild without being harsh. The properties of raw and charred are different. Raw use is pungent, dispersing, sweet and mild, slightly warm and mild, enters the bladder and spleen meridians, dispels external wind, overcomes dampness and relieves pain; enters the liver meridian, dispels internal wind and stops spasms. It is a general medicine for treating wind, dispersing external wind and calming internal wind, and can treat wind-cold, wind-heat and exterior symptoms with dampness. It is most suitable for the three evils of wind, cold and dampness. It is astringent and ascending dispersing, enters the spleen and liver meridians and is good at stopping bleeding and diarrhea. It is suitable for treating metrorrhagia and diarrhea.

[0037] Roasted licorice root is sweet and mild in nature, and it enters the heart, lung, spleen, and stomach meridians. Sweet licorice root is nourishing and moistening, and it is cool in nature when raw, and warm in nature when roasted, and it mainly enters the spleen and lung meridians, and also enters the stomach and heart meridians. It can not only replenish qi and nourish the middle, but also relieve pain, moderate the properties of the medicine, and also eliminate phlegm, relieve cough, and detoxify. Honey roasted licorice root has strong effect of replenishing qi and relieving urgency.

[0038] According to traditional Chinese medicine, chronic diarrhea of ​​spleen and stomach deficiency and cold syndrome is mainly caused by excessive cold food, which damages spleen yang. The spleen is healthy when it rises, and it likes dryness and hates dampness, warmth and coldness. Coldness is the main cause of contraction, which can easily lead to stagnation of qi and blood. The spleen and stomach cannot rise and fall properly, which leads to cold and dampness. Dampness is heavy and turbid, and belongs to yin. It is easy to trap spleen and earth. If it stays in the body for too long, it will further damage spleen yang and form the syndrome of spleen and stomach deficiency and coldness. Fire does not warm the earth, the spleen loses its healthy function, there is no fire in the stomach, food cannot be digested, and water and dampness stagnate. It can be seen that the abdomen is cold and painful, bloating, belching, vomiting clear water, loss of appetite, loose stools or indigestion, enlarged tongue, tooth marks on the sides of the tongue, and white and moist fur. Therefore, chronic diarrhea of ​​spleen and stomach deficiency and cold syndrome is located in the spleen, stomach and intestines. The basic pathogenesis is internal obstruction of dampness, abnormal function of spleen, stomach and intestines in transporting and secreting turbidity, and poor qi in the middle jiao. Dampness and spleen deficiency are the key to diarrhea. Therefore, the treatment of chronic diarrhea due to spleen and stomach deficiency and cold syndrome should be based on the principles of strengthening the spleen and replenishing Qi, drying dampness and relieving constipation, and supporting the positive Qi to achieve the purpose of stopping diarrhea.

[0039] Therefore, the present invention uses Agrimoniae, Acorus calamus and Atractylodes macrocephala as the main drugs, Agrimoniae is used to tonify deficiency and replenish qi, Acorus calamus can dispel phlegm and eliminate dampness, dry dampness and harmonize the stomach, and Atractylodes macrocephala can dispel cold and strengthen the spleen, dry dampness and promote diuresis, and the three are combined to achieve the effects of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis;

[0040] With dried ginger, psoralea corylifolia, schisandra chinensis, nutmeg, cinnamon bark, patchouli, and yam as assistant drugs, dried ginger and cinnamon bark can warm the middle and dispel cold, dispel cold air, and help the main drug to dispel dampness caused by cold, schisandra chinensis and psoralea corylifolia can consolidate kidney yang and help the main drug to strengthen the positive energy, yam can help the main drug to strengthen the spleen and stomach, and nutmeg can promote qi and remove stagnation. The assistant drugs can help the main drug to strengthen the spleen and stomach and promote the flow of qi in the middle jiao.

[0041] With Corydalis yanhusuo, white peony root, charred hawthorn, pomegranate peel, plantain, red ochre, terminalia chebula, and saposhnikovia as adjuvants, Corydalis yanhusuo and terminalia chebula are used to promote qi and relieve pain, charred hawthorn is used to invigorate the spleen and promote qi, pomegranate peel, red ochre, terminalia chebula are used to astringe the intestines and stop diarrhea, white peony root is used to promote blood circulation and remove blood stasis, and pomegranate peel and red ochre are used to astringe, so as to repair the intestinal mucosa and prevent bleeding, and plantain is used to promote diuresis and promote urination to solidify the stool;

[0042] Using licorice as the adjuvant drug to harmonize various drugs, and using dried ginger and cinnamon as the guiding drugs at the same time. Using dried ginger to guide cold out of the orifices, and using cinnamon to guide fire back to its origin.

[0043] The beneficial effects achieved by adopting the present invention are as follows:

[0044] The present invention rationally combines drugs according to the etiology and pathogenesis of chronic diarrhea of the syndrome type of deficiency-cold of the spleen and stomach. With the synergistic effect of various drugs, it can invigorate the spleen and replenish qi, dry dampness and promote diuresis, assist healthy qi and smooth the qi movement in the middle-jiao, so as to achieve the purpose of stopping diarrhea and effectively treat chronic diarrhea of the syndrome type of deficiency-cold of the spleen and stomach. Specific embodiments

[0045] In order to make the purpose, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with its embodiments; it should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0046] Embodiment 1: A traditional Chinese medicine composition for treating chronic diarrhea, characterized in that it is composed of the following raw materials by weight:

[0047] 10 parts of Agrimonia pilosa Ledeb., 15 parts of Acorus tatarinowii Schott, 10 parts of Atractylodes lancea (Thunb.) DC., 10 parts of dried ginger, 5 parts of Psoralea corylifolia L., 5 parts of Schisandra chinensis (Turcz.) Baill., 10 parts of Myristica fragrans Houtt., 3 parts of cinnamon, 10 parts of Pogostemon cablin (Blanco) Benth., 5 parts of Dioscorea opposita Thunb., 10 parts of Corydalis yanhusuo W. T. Wang, 15 parts of Paeonia lactiflora Pall., 10 parts of Hawthorn Fruit, 10 parts of Granatum pericarpium, 5 parts of Plantago asiatica L., 5 parts of Halloysitum rubrum, 5 parts of Terminalia chebula Retz., 5 parts of Saposhnikovia divaricata (Turcz.) Schischk., 5 parts of roasted licorice.

[0048] When specifically applied, the dosage of one dose of medicine in this embodiment is:

[0049] 10 g of Agrimonia pilosa Ledeb., 15 g of Acorus tatarinowii Schott, 10 g of Atractylodes lancea (Thunb.) DC., 10 g of dried ginger, 5 g of Psoralea corylifolia L., 5 g of Schisandra chinensis (Turcz.) Baill., 10 g of Myristica fragrans Houtt., 3 g of cinnamon, 10 g of Pogostemon cablin (Blanco) Benth., 5 g of Dioscorea opposita Thunb., 10 g of Corydalis yanhusuo W. T. Wang, 15 g of Paeonia lactiflora Pall., 10 g of Hawthorn Fruit, 10 g of Granatum pericarpium, 5 g of Plantago asiatica L., 5 g of Halloysitum rubrum, 5 g of Terminalia chebula Retz., 5 g of Saposhnikovia divaricata (Turcz.) Schischk., 5 g of roasted licorice.

[0050] Embodiment 2: A traditional Chinese medicine composition for treating chronic diarrhea, characterized in that it is composed of the following raw materials by weight:

[0051] 8 parts of Agrimonia pilosa Ledeb., 10 parts of Acorus tatarinowii Schott, 10 parts of Atractylodes lancea (Thunb.) DC., 5 parts of dried ginger, 5 parts of Psoralea corylifolia L., 5 parts of Schisandra chinensis (Turcz.) Baill., 5 parts of Myristica fragrans Houtt., 3 parts of cinnamon, 10 parts of Pogostemon cablin (Blanco) Benth., 5 parts of Dioscorea opposita Thunb., 5 parts of Corydalis yanhusuo W. T. Wang, 10 parts of Paeonia lactiflora Pall., 10 parts of Hawthorn Fruit, 10 parts of Granatum pericarpium, 2 parts of Plantago asiatica L., 5 parts of Halloysitum rubrum, 5 parts of Terminalia chebula Retz., 5 parts of Saposhnikovia divaricata (Turcz.) Schischk., 5 parts of roasted licorice.

[0052] When specifically applied, the dosage of one dose of medicine in this embodiment is:

[0053] 8g of Agrimonia pilosa Ledeb., 10g of Acorus tatarinowii Schott, 10g of Atractylodes lancea (Thunb.) DC., 5g of Dry Ginger, 5g of Psoralea corylifolia L., 5g of Schisandra chinensis (Turcz.) Baill., 5g of Myristica fragrans Houtt., 3g of Cinnamomum cassia Presl, 10g of Pogostemon cablin (Blanco) Benth., 5g of Dioscorea opposita Thunb., 5g of Corydalis yanhusuo W. T. Wang, 10g of Paeonia lactiflora Pall., 10g of Hawthorn Fruit (processed), 10g of Granatum Bark, 2g of Plantago asiatica L., 5g of Halloysitum Rubrum, 5g of Terminalia chebula Retz., 5g of Saposhnikovia divaricata (Turcz.) Schischk., 5g of Honey-fried Licorice Root.

[0054] Example 3: A traditional Chinese medicine composition for treating chronic diarrhea, characterized in that it is composed of the following raw materials by weight:

[0055] 20 parts of Agrimonia pilosa Ledeb., 20 parts of Acorus tatarinowii Schott, 5 parts of Atractylodes lancea (Thunb.) DC., 15 parts of Dry Ginger, 5 parts of Psoralea corylifolia L., 5 parts of Schisandra chinensis (Turcz.) Baill., 15 parts of Myristica fragrans Houtt., 5 parts of Cinnamomum cassia Presl, 10 parts of Pogostemon cablin (Blanco) Benth., 10 parts of Dioscorea opposita Thunb., 10 parts of Corydalis yanhusuo W. T. Wang, 15 parts of Paeonia lactiflora Pall., 15 parts of Hawthorn Fruit (processed), 10 parts of Granatum Bark, 2 parts of Plantago asiatica L., 5 parts of Halloysitum Rubrum, 5 parts of Terminalia chebula Retz., 5 parts of Saposhnikovia divaricata (Turcz.) Schischk., 5 parts of Honey-fried Licorice Root.

[0056] For specific practical application, the dosage of one dose of medicine in this example is:

[0057] 8g of Agrimonia pilosa Ledeb., 10g of Acorus tatarinowii Schott, 10g of Atractylodes lancea (Thunb.) DC., 5g of Dry Ginger, 5g of Psoralea corylifolia L., 5g of Schisandra chinensis (Turcz.) Baill., 5g of Myristica fragrans Houtt., 3g of Cinnamomum cassia Presl, 10g of Pogostemon cablin (Blanco) Benth., 5g of Dioscorea opposita Thunb., 5g of Corydalis yanhusuo W. T. Wang, 10g of Paeonia lactiflora Pall., 10g of Hawthorn Fruit (processed), 10g of Granatum Bark, 2g of Plantago asiatica L., 5g of Halloysitum Rubrum, 5g of Terminalia chebula Retz., 5g of Saposhnikovia divaricata (Turcz.) Schischk., 5g of Honey-fried Licorice Root.

[0058] The traditional Chinese medicine compositions of Examples 1 to 3 can be made into a decoction for taking.

[0059] Specifically, the preparation steps of the decoction are as follows

[0060] 1) After taking the raw materials according to the amount, they are respectively pulverized and then mixed;

[0061] 2) 1000 of water is added to the mixture in step 1). After boiling over high heat, under the condition of reflux, it is decocted over low heat for 40 - 60 minutes, then filtered, and the filtrate is taken;

[0062] 3) 1000 ml of water is added to the medicinal residues after filtration in step 2). After boiling over high heat, under the condition of reflux, it is decocted over low heat for 40 - 60 minutes, then filtered;

[0063] 4) The filtrates of the two times are combined and heated until the liquid reaches 300 - 500 ml.

[0064] Clinical application:

[0065] A total of 54 patients with chronic diarrhea diagnosed with the syndrome of deficiency-cold of the spleen and stomach who visited our hospital from 2020 to 2022 were reviewed. Among them, 34 were male and 20 were female, aged between 27 and 76 years. Among them, 23 patients were treated with Koufuguchangzhixie Pills, as the control group, 1 bag each time (produced by Shaanxi University of Chinese Medicine Pharmaceutical Factory, national drug approval number: Z61020796, 5g / bag), 3 times a day. 31 patients were treated with the decoction of Example 1, as the experimental group, one dose per day.

[0066] Observation items: Mainly observe the integral changes of traditional Chinese medicine symptoms and signs (including abdominal distension and pain, loss of appetite, fear of cold and cold limbs, fatigue and weakness, tastelessness in the mouth and no thirst, soreness of the waist and knees, listlessness and reluctance to talk, etc.) before and after treatment. Score according to mild, moderate and severe degrees, 0 points for no symptoms, 1 point for mild, 2 points for moderate, and 3 points for severe.

[0067] Statistics were made on the curative effects of the above patients after one course of treatment (two weeks) and two courses of treatment respectively.

[0068] Curative effect criteria:

[0069] Observation items:

[0070] Mainly observe the integral changes of traditional Chinese medicine symptoms and signs (including abdominal distension and pain, loss of appetite, fear of cold and cold limbs, fatigue and weakness, tastelessness in the mouth and no thirst, soreness of the waist and knees, listlessness and reluctance to talk, etc.) before and after treatment. Score according to mild, moderate and severe degrees, 0 points for no symptoms, 1 point for mild, 2 points for moderate, and 3 points for severe.

[0071] Curative effect criteria:

[0072] It was formulated with reference to the curative effect criteria of diarrhea in "Guiding Principles for Clinical Research of New Chinese Medicines" (trial).

[0073] Clinical cure: The frequency, volume and character of stools return to normal, accompanying symptoms disappear, and physical and chemical tests related to diarrhea are normal. Marked effect: The stools are 2 - 3 times a day, the stools are approximately formed, or loose stools once a day, and the total integral of traditional Chinese medicine symptoms and signs is reduced by more than 70% compared with that before treatment, and the physical and chemical examinations related to diarrhea are improved.

[0074] Effective: The frequency and quality of stools are improved, the total integral of traditional Chinese medicine symptoms and signs is reduced by 35% - 69% compared with that before treatment, and the physical and chemical examinations related to diarrhea are improved.

[0075] Ineffective: The effective standard is not reached.

[0076] Effective rate = (clinical cure + effective) * 100% / total number of people

[0077] The curative effect results are shown in Table 1 below:

[0078]

[0079] For the patients in the upper control group, those with ineffective treatment after two courses of treatment stopped taking Guchang Zhixie Pills and switched to taking the medicine in Example 1 for continuous treatment. For those in the control group who showed ineffective treatment after two courses, other methods were used for continuous treatment.

[0080] Typical Cases

[0081] Case 1: Li XX, male, 75 years old, was admitted to the hospital due to chest distress, shortness of breath, cough, and expectoration.

[0082] After admission, the patient was diagnosed with acute exacerbation of chronic bronchitis, pulmonary emphysema, and cor pulmonale. Oxygen inhalation, anti-infection, antispasmodic and antiasthmatic, cardiotonic and diuretic, and electrolyte supplementation treatments were given, and the patient's symptoms were relieved. On the 15th day of hospitalization, the patient suddenly developed diarrhea. At first, the stools were loose, 3 - 4 times a day, and then gradually increased to more than ten times a day, mainly watery stools, without abdominal pain, accompanied by abdominal distension, loss of appetite, nausea, retching, and belching after eating. The routine stool examination was normal, and no bacteria grew in the stool culture. While receiving antibiotic treatment, the patient took compound diphenoxylate tablets, smecta, and multi-enzyme tablets orally, but the symptoms were not significantly relieved, and the chest distress and shortness of breath worsened, and the patient was listless. Therefore, a traditional Chinese medicine consultation was requested. It was found that the patient had a pale tongue with white and greasy coating, and a slow and weak pulse.

[0083] Considering that the patient's condition was caused by weakness of the spleen and stomach, deficiency of middle yang, and internal obstruction of damp pathogens, the water decoction in Example 1 was used for treatment, one dose per day. After taking the medicine for three days, the patient's diarrhea frequency decreased to 6 - 7 times a day, and the treatment was effective. The patient continued to take the medicine for another 3 doses.

[0084] At the third consultation, the patient had 3 - 4 bowel movements a day, with loose stools. The diet increased, but there was still abdominal distension after eating, no nausea or belching, and dry mouth. The patient took another 4 doses of medicine for consolidation. The patient's stools were basically formed, 1 - 2 times a day, and there was no recurrence of diarrhea until discharge.

[0085] Case 2: Zhang XX, female, 40 years old.

[0086] First diagnosis: April 7, 2020.

[0087] Chief complaint and medical history: Diarrhea for more than a month, 4 - 5 times a day, lack of appetite when hungry, lack of thirst when thirsty, fatigue, and no feeling of abdominal distension or distress.

[0088] Examination: Sallow complexion, lack of energy, pale red tongue with thin and rough coating, and stringy and thready pulse. The abdomen was flat and soft, the liver and spleen were not enlarged, and there was no tenderness or rebound tenderness. Syndrome differentiation: Deficiency of kidney yang and deficiency-cold of spleen and stomach.

[0089] After the first diagnosis, the doctor's advice was to use the traditional Chinese medicine composition in Example 1 for water decoction treatment, one dose per day.

[0090] Second diagnosis: April 10.

[0091] Feedback: Diarrhea stopped after taking 1 dose of the water decoction, the stools were soft, and there was 1 bowel movement a day. After taking 3 doses of the medicine, the stools returned to normal.

[0092] Case 3: Wang Mou, male, 49 years old.

[0093] First diagnosis: October 18, 2023

[0094] Chief complaint: Vomiting and diarrhea, occurring once at 12 o'clock at night every week. It is unbearable when having the urge to defecate.

[0095] Diagnosis: Usually having loose stools, it is unbearable when having the urge to defecate, twice a day. He has been treated by traditional Chinese medicine in many places without effect; on percussion, there is tympany in the right abdomen, the abdomen is soft, there is abdominal pain before diarrhea, and the pain is relieved after diarrhea; not afraid of cold, sweating significantly; bronchiectasis was caused by a cold, and there was hematemesis during the onset; on inspection, the face is pale, the spirit is listless, the lower eyelids are swollen, the facial red spots are obvious, the calves are pale, and the hair is all white; nocturia is normal, smoking addiction; 86 kg, 177 cm; the tongue is red, the tongue coating is slippery, less meridian, obviously cyanotic, with slightly transverse cracks, the tongue body is enlarged, the left pulse is thready, rapid and weak, and the left chi pulse is deep.

[0096] Syndrome differentiation: Deficiency-cold of the spleen and stomach.

[0097] After the first diagnosis, the doctor's advice was to decoct and take the traditional Chinese medicine composition of Example 1, one dose per day.

[0098] Second diagnosis on October 23. After taking the medicine for five days, the vomiting and diarrhea were significantly reduced. In recent days, there was no unbearable feeling before defecation and no abdominal pain. The tongue was red, the tongue coating was white, less meridian, obviously cyanotic, with slightly transverse cracks seen superficially, the left pulse was thready, and the left chi pulse was deep. Continue to take the medicine to consolidate the curative effect.

[0099] Third diagnosis on October 30. All symptoms had no obvious symptoms, no urge to defecate at night, no vomiting and diarrhea, no abdominal pain before defecation, having a bowel movement once a day, the stool was slightly formed. The patient was very happy and continued to take the medicine for one week to consolidate the curative effect.

[0100] Case 4: Li Mou, male, 27 years old, came for diagnosis on October 10, 2021 due to "diarrhea for 3 months". There was no special past medical history, and he had been staying up late due to work for a long time.

[0101] The patient reported that 3 months ago, without obvious inducement, he had loose stools, abdominal distension and discomfort, no obvious abdominal pain, normal appetite, dry mouth and bitter taste in the morning, no thirst, and frequent neck pain. He went to the hospital for treatment, and was prescribed Jianpi Keli, Zhengchangsheng, and Bifidobacterium bifidum enteric-coated capsules, but there was no effect. He came for diagnosis and requested traditional Chinese medicine treatment. Current symptoms: loose stools, dry mouth and bitter taste in the morning, abdominal distension and discomfort, no thirst, normal appetite, afraid of cold, shoulder and back pain, normal urination, pale and tender tongue, white and greasy tongue coating in the middle of the tongue, and deep and weak pulse. The traditional Chinese medicine composition of Example 1 was used for treatment, one dose per day. All symptoms improved after one week, and another seven doses were given for rehabilitation.

[0102] Case 5: Hai Mou, male, 32 years old, visited on November 14, 2020. Chief complaint: Repeated diarrhea for 15 years, 3 - 5 times a day. Recently, due to eating unclean food, he had diarrhea for 2 days, 7 times a day, with mucus and abdominal pain. The tongue was slightly red, the tongue coating was white, the pulse was tense, rapid and empty on heavy pressing.

[0103] Traditional Chinese medicine diagnosed dysentery.

[0104] Syndrome type: deficiency-cold of the spleen and stomach.

[0105] For the first diagnosis, six doses of the composition in Example 1 were administered, one dose per day, decocted in water for oral administration, and taken separately in the morning and evening.

[0106] Follow-up visit: On November 20, 2020, the bowel movement was twice a day, with occasional purulent strips and blood streaks, and slightly tenesmus. The tongue was pale red with a thick coating, the body was plump and large, and the pulse was deep and tight.

[0107] For the follow-up visit, seven doses of the composition in Example 1 were continuously administered, one dose per day, decocted in water for oral administration, and taken separately in the morning and evening.

[0108] Third diagnosis: On January 2, 2021, the weight increased by 8 catties. Recently, after eating seafood, the bowel movement was three times a day and formed. The tongue was pale red with a white coating, the body was plump and large, and the pulse was slightly rapid and soft.

[0109] After the third diagnosis, six doses of the composition in Example 1 were continuously administered, one dose per day, decocted in water for oral administration, and taken separately in the morning and evening.

[0110] Fourth diagnosis: On January 9, 2020, the bowel movement was formed, 1-2 times a day. The tongue was slightly red with a white coating, the body was plump and large, and the pulse was slightly rapid. Six doses of the composition in Example 1 were continuously administered, one dose per day, decocted in water for oral administration, and taken separately in the morning and evening. Follow-up visit showed complete recovery.

[0111] Case 6: Gao, female, 68 years old.

[0112] She reported having had diarrhea for more than two years. Every morning, there was borborygmus first and then diarrhea, and she felt slightly relieved after diarrhea. The stools were loose, accompanied by dull pain in the abdomen, aversion to cold and cold limbs, soreness and weakness in the waist and legs. All symptoms were sometimes mild and sometimes severe, lingering and difficult to heal. The tongue was pale with a white coating, and the pulse was deep and thready. Inquiring about her medical history, she had suffered from chronic bronchitis and chronic gastritis for many years and had taken medicine intermittently; one month ago, she had an operation for "acute appendicitis" at the local people's hospital. During the hospitalization, liver and kidney function, blood sugar and lipid tests, and X-ray barium meal fluoroscopy of the whole digestive tract were all normal. She had taken traditional Chinese and Western medicines such as "Smecta", "Imodium" and "Bupi Yichang Pills" but had not seen obvious curative effects.

[0113] Western medicine diagnosis: chronic diarrhea.

[0114] Traditional Chinese medicine diagnosis: diarrhea, deficiency-cold of the spleen and stomach.

[0115] It was treated by decocting and taking the traditional Chinese medicine composition in Example 1, one dose per day, for 2 weeks, and the patient recovered completely.

[0116] Case 7: Yuan, female, 70 years old.

[0117] Chief complaint: repeated diarrhea for more than 1 year.

[0118] Present illness history: The patient reported having diarrhea for nearly 1 year, 3 - 5 times a day. Sometimes, the diarrhea was like thin water, which was obvious after getting cold or eating cold food. There was sometimes dull pain in the abdomen, and often dizziness and fatigue. The tongue was dull and dark, the tongue coating was white, and the pulse was thready and weak.

[0119] Past history: Once diagnosed with: Chronic enteritis.

[0120] Auxiliary examination: None.

[0121] Traditional Chinese medicine diagnosis: Diarrhea, deficiency - cold of the spleen and stomach

[0122] Treated with the traditional Chinese medicine composition in Example 1 by decocting and taking orally, one dose per day. The symptoms disappeared after 3 weeks of medication.

[0123] Case 8: Wang Mou, female, 36 years old.

[0124] First visit on May 13, 2020

[0125] Diarrhea occurred intermittently for more than one month and worsened for one week.

[0126] Previously, gastroscopy and colonoscopy in another hospital showed: Superficial gastritis, gastric polyps.

[0127] Diarrhea in the past two days, accompanied by fever in the palms and soles of the feet, came for treatment

[0128] Chief complaint: Diarrhea, the stool is three to four times a day, unformed, with a sour smell, fatigue, fever in the palms and soles of the feet, phlegm in the throat, shortness of breath.

[0129] The tongue is pale, and the tongue coating is white and slightly greasy

[0130] Syndrome differentiation: Deficiency - cold of the spleen and stomach, endogenous phlegm - turbidity.

[0131] Treatment principle: Tonify qi, strengthen the spleen, resolve dampness and expel turbidity.

[0132] Treated with the traditional Chinese medicine composition in Example 1 by decocting and taking orally, 7 doses, decocted and taken orally, 1 dose per day, taken separately in the morning and evening.

[0133] Follow - up visit on May 20, 2020

[0134] Chief complaint: Diarrhea improved, twice a day, unformed, sour smell reduced, cold feet and sweating.

[0135] Body temperature is normal

[0136] Continue to take 6 doses, decocted and taken orally, 1 dose per day, taken separately in the morning and evening.

[0137] Third visit on May 26, 2020

[0138] Chief complaint: Diarrhea continued to improve, occasionally formed stools, smell reduced, and other symptoms all improved.

[0139] Continue to take 7 doses, decocted and taken orally, 1 dose per day, taken separately in the morning and evening.

[0140] Four diagnostic methods on June 4, 2020

[0141] Chief complaint: Diarrhea and abdominal pain have stopped, and the stools are occasionally unformed. Other symptoms have alleviated, but the sleep is not good.

[0142] Case 9: Zhao, female, 23 years old.

[0143] Chief complaint and medical history: Since 2019, the stools have been loose and intermittent. Various traditional Chinese and Western medicines have been taken but not cured. Since the winter of 2020, the frequency of diarrhea has increased, especially at night, so she came for diagnosis and treatment.

[0144] Examination: During the diagnosis, the patient has bowel movements two or three times during the day and one or two times at night. There is borborygmus, abdominal distension and pain before defecation, frequent flatulence, and great distress. The abdomen feels comfortable after defecation. Associated symptoms include excessive sweating, hot palms, thirst, poor appetite, soreness in the waist, heaviness and discomfort in the lower limbs, preference for warmth in the waist, and amenorrhea. The pulse is deep and thready, the tongue is pale, and the tongue coating is white, slippery and greasy.

[0145] Syndrome differentiation: The syndrome is due to deficiency-cold of the spleen and stomach, and the binding and obstruction of cold-dampness and stagnant heat.

[0146] After the first diagnosis, the patient was given the traditional Chinese medicine composition in Example 1 for decoction and oral administration, one dose per day.

[0147] Second diagnosis: After taking 4 doses of medicine, the abdominal pain is slightly relieved, and there is no other improvement.

[0148] Medical advice for the second diagnosis: Continue to take the medicine.

[0149] Third diagnosis: After taking another 4 doses of medicine, the abdominal pain is greatly reduced, flatulence is less, and there is no diarrhea at night. The tongue coating becomes thinner. Menstruation comes, with a small amount and purple color. After taking 7 more doses of medicine, all symptoms improve. After following up for half a year, there is no recurrence of diarrhea.

[0150] Case 10: Wang, female, 60 years old.

[0151] She reported having repeated mucoid stools for 2 years. During the course of the disease, a large amount of traditional Chinese and Western medicines have been taken, but the effect is not obvious. Symptoms include borborygmus and abdominal pain, diarrhea when the pain occurs, pain relief after defecation, stools white like fish brain, especially severe when sitting upright, standing, or walking, having bowel movements 7 - 10 times a day, accompanied by fullness and discomfort in the epigastric and abdominal regions, fatigue, pale complexion, poor appetite, clear and long urine, aversion to cold and cold limbs, soreness and weakness in the waist and knees, pale and plump tongue with tooth marks on the edges, white and greasy tongue coating, and deep and slow pulse.

[0152] After the initial diagnosis, the patient was instructed to take the traditional Chinese medicine composition of Example 1 by decocting in water, one dose per day. After taking the medicine for one week, the patient came for a follow-up visit. The patient reported that various symptoms had been relieved to some extent after taking the medicine. The patient had bowel movements 3 to 4 times a day, and the mucus in the stools had significantly decreased. However, the tongue was still pale and plump, with tooth marks on the sides, the tongue coating was white and greasy, and the pulse was deep and slow. The patient was instructed to continue taking the traditional Chinese medicine composition of Example 1 for another ten doses. Twenty days later, the patient came for the third visit. The patient reported that various symptoms had been significantly relieved after taking the medicine. The patient had bowel movements 1 to 2 times a day, and the mucus in the stools had basically disappeared. The tongue was light red, the tongue body was plump with tooth marks on the sides, the tongue coating was thin and white and greasy, and the pulse was soggy and slow. The patient continued to take ten doses, one dose per day, by decocting in water. One month later, the patient came for the fourth visit. The patient had a bowel movement once a day, and the mucus in the stools had disappeared. The tongue was light red, the tongue coating was thin and white and greasy, and the pulse was soggy and slow. The patient continued the treatment to consolidate the effect. Three months later, a follow-up visit was made, and the diarrhea did not occur again.

[0153] The above are only the preferred embodiments of the present invention. It should be pointed out that for those of ordinary skill in the art of this technology, without departing from the principle of the present invention, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. A Chinese medicine composition for treating chronic diarrhea, characterized in that: It is composed of the following raw materials by weight: 8-20 parts of Agrimoniae, 5-25 parts of Acorus calamus, 5-20 parts of Atractylodes, 5-20 parts of dried ginger, 2-10 parts of Psoralea corylifolia, 2-10 parts of Schisandra chinensis, 5-20 parts of Nutmeg, 1-5 parts of Cinnamon bark, 5-20 parts of Patchouli, 2-10 parts of Dioscorea opposita, 5-20 parts of Corydalis yanhusuo, 8-20 parts of White Peony Root, 8-20 parts of Charred Crataegus pinnatifida, 8-20 parts of Pomegranate peel, 2-10 parts of Plantain, 2-10 parts of Red Ochre, 2-10 parts of Terminalia chebula, 2-10 parts of Saposhnikovia divaricata, and 2-10 parts of Radix Glycyrrhizae Preparata.

2. A Chinese medicine composition for treating chronic diarrhea according to claim 1, characterized in that: It is composed of the following raw materials by weight: 10 parts of Herba Agrimoniae, 15 parts of Rhizoma Acoruscae, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Dried Ginger, 5 parts of Psoralea Corylifoliae, 5 parts of Fructus Schisandrae Chinensis, 10 parts of Myristica Fragrance, 3 parts of Cinnamon Bark, 10 parts of Patchouli, 5 parts of Dioscorea Oppositae, 10 parts of Corydalis Scutellariae, 15 parts of White Peony Root, 10 parts of Charred Crataegus Pinelliae, 10 parts of Pomegranate Peel, 5 parts of Herba Plantaine, 5 parts of Red Ochre, 5 parts of Terminalia Chebula, 5 parts of Saposhnikovia Divaricata, and 5 parts of Radix Glycyrrhizae Preparata.

3. A Chinese medicine composition for treating chronic diarrhea according to claim 1, characterized in that: It is composed of the following raw materials by weight: 8 parts of Herba Agrimoniae, 10 parts of Rhizoma Acoruscae, 10 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of Dried Ginger, 5 parts of Psoralea Corylifolia, 5 parts of Fructus Schisandrae Chinensis, 5 parts of Myristica Fragrance, 3 parts of Cinnamon Bark, 10 parts of Patchouli, 5 parts of Dioscorea Oppositae, 5 parts of Corydalis Sinensis, 10 parts of White Peony Root, 10 parts of Charred Crataegus, 10 parts of Pomegranate Peel, 2 parts of Herba Plantaine, 5 parts of Red Ochre, 5 parts of Terminalia Terminaliae, 5 parts of Saposhnikovia Divaricata, and 5 parts of Radix Glycyrrhizae Preparata.

4. A Chinese medicine composition for treating chronic diarrhea according to claim 1, characterized in that: It is composed of the following raw materials by weight: 20 parts of Herba Agrimoniae, 20 parts of Rhizoma Acoruscae, 5 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of Dried Ginger, 5 parts of Psoralea Corylifoliae, 5 parts of Fructus Schisandrae Chinensis, 15 parts of Myristica Fragrance, 5 parts of Cinnamon Bark, 10 parts of Patchouli, 10 parts of Dioscorea Oppositae, 10 parts of Corydalis Scutellariae, 15 parts of White Peony Roots, 15 parts of Charred Crataegus, 10 parts of Pomegranate Peel, 2 parts of Herba Plantaine, 5 parts of Red Ochre, 5 parts of Terminalia Terminaliae, 5 parts of Saposhnikovia Divaricatae, and 5 parts of Radix Glycyrrhizae Preparata.

5. Use of a traditional Chinese medicine composition for treating chronic diarrhea according to any one of claims 1 to 4 in the preparation of a medicament for treating chronic diarrhea.

6. The use according to claim 5, characterized in that: The chronic diarrhea is chronic diarrhea of ​​spleen and stomach deficiency and cold syndrome.

7. The use according to claim 5, characterized in that: The dosage form of the medicine is an oral dosage form.

8. The use according to claim 7, characterized in that: The oral dosage forms include powders, granules, capsules, tablets, pills and solutions.

9. The use according to any one of claims 5 to 8, characterized in that The medicine uses as an effective ingredient an extract or an extract prepared from a Chinese medicine composition for treating chronic diarrhea as claimed in any one of claims 1 to 4 as a raw material.

Images