Compound medicament for treating burns and scalds and preparation method thereof

Abstract

The invention relates to a compound medicament for treating burns and scalds and a preparation method thereof, and the compound medicament is prepared from borneol powder, catechu powder, indigo naturalis powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and an organic preservative according to a ratio of 2: 2: 2: 2: 1.5: 1: 50: 0.25. The borneol powder, the catechu powder, the indigo naturalis powder, the lithospermum powder, the calcium carbonate, the egg white protein powder, the refined rapeseed oil and the organic preservative are put into a sterile and anhydrous container to be mixed in proportion, the time is not limited, the mixture is fully and evenly stirred, and a mixture is obtained; and 2, filling the mixture into a glass bottle, carrying out vacuum sealing storage, taking out the mixture for use when the mixture needs to be used later, and directly smearing the mixture on an affected part, so that the healing effect on injuries of human skin, muscular tissues, meridians, bones and the like after burns and scalds can be remarkably improved.

Description

Technical Field

[0001] This application belongs to the technical field of treating burns and scalds, and in particular relates to a compound medicament for treating burns and scalds and a preparation method thereof. Background Art

[0002] Burns and scalds are injuries to the skin, muscles, tendons and bones caused by boiling water, hot oil, steam, fire, hot metal liquids or solids, electricity, chemical substances, radiation or firearms in wartime.

[0003] At present, most Western medicines and injections for treating burns and scalds use painkillers for pain relief and antibiotics to prevent infection. They have large side effects, strong drug resistance, unstable curative effects, difficult wound healing, and easy muscle loss and depression after healing; traditional Chinese medicine decoctions and injections have certain curative effects, but there are many toxic and side effects, long treatment cycles, slow muscle growth speed, common hyperplasia and melanin deposition at the affected area after healing. Moreover, common external medicated ointments for treating burns and scalds will cause slight secondary damage to fragile wounds when used, and when the pharmaceutical preparation is used externally, its adhesion on the surface of the lesion is not strong, which greatly reduces the drug efficacy. Summary of the Invention

[0004] The technical problem to be solved by the present invention is: to solve the deficiencies of large side effects and unstable curative effects of Western medicines and injections in the prior art, and the weak adhesion of traditional Chinese medicine decoctions and injections on the surface of the lesion when used externally, which greatly reduces the drug efficacy, so as to provide a compound medicament for treating burns and scalds and a preparation method thereof.

[0005] The technical solution adopted by the present invention to solve its technical problems is:

[0006] A compound medicament for treating burns and scalds, the components of the compound medicament are composed of the following raw materials:

[0007] Borneol powder of traditional Chinese medicine for clearing heat and relieving pain, preventing corrosion, promoting granulation and resuscitating the mind;

[0008] Catechu powder of traditional Chinese medicine for cooling blood and removing stasis, astringing bleeding, promoting granulation and anti-ulcer;

[0009] Indigo naturalis powder of traditional Chinese medicine for clearing heat and detoxifying, activating blood circulation and removing stasis, and removing macules;

[0010] Arnebia root powder of traditional Chinese medicine for cooling blood and activating blood circulation, and also for detoxifying and promoting eruption, and removing macules;

[0011] Calcium carbonate that can prevent edema, reduce inflammation, protect vascular endothelial cells and promote wound healing, and the molecular formula of calcium carbonate is CaCO 3 ;

[0012] Egg white protein powder that is beneficial to the healing of wounds and incisions and can maintain the normal functions and metabolism of cells. The egg white protein powder is food grade, or fresh egg white can be selected;

[0013] Antioxidant refined rapeseed oil;

[0014] Organic preservative, and the organic preservative is potassium sorbate;

[0015] Specifically, the ratio of borneol powder, catechu powder, indigo naturalis powder, lithospermum erythrorhizon powder, calcium carbonate, egg white protein powder / fresh egg white, refined rapeseed oil, and organic preservative is = 2:2:2:2:1.5:1:50:0.25.

[0016] The mesh number of borneol powder is 800 - 1000 mesh, and the catechu powder, indigo naturalis powder, lithospermum erythrorhizon powder, and egg white protein powder can also be 800 - 1000 mesh.

[0017] The catechu powder, indigo naturalis powder, and lithospermum erythrorhizon powder are all top-grade medicinal materials. Top-grade Chinese medicinal materials are the highest grade of Chinese medicinal materials, with excellent quality and remarkable medicinal effects. The raw materials of these Chinese medicinal materials are sourced from the purest and highest-quality origins in the world, and through strict screening and processing techniques, their purity and integrity of active ingredients are ensured. Top-grade Chinese medicinal materials are commonly used in important traditional Chinese medicine formulas and have extensive applications in the pharmaceutical field.

[0018] A preparation method of a compound medicament for treating burns and scalds, comprising the following steps:

[0019] Step 1: In a sterile environment, put borneol powder, catechu powder, indigo naturalis powder, lithospermum erythrorhizon powder, calcium carbonate, egg white protein powder / fresh egg white, refined rapeseed oil, and organic preservative in a sterile and water-free container and mix them in proportion for an unlimited time, and just stir well to obtain a mixture;

[0020] Step 2: Pack the mixture into a glass bottle and store it under vacuum seal. When it needs to be used later, take it out for use.

[0021] Among them, the dried root of lithospermum erythrorhizon in Step 1 needs to be soaked in refined rapeseed oil for more than 48 hours first, then take out the lithospermum erythrorhizon root to obtain lithospermum erythrorhizon oil; then weigh borneol powder, catechu powder, indigo naturalis powder, calcium carbonate, egg white protein powder or fresh egg white, and potassium sorbate in proportion and put them into the prepared lithospermum erythrorhizon oil, and stir well to obtain a mixture.

[0022] For the treatment of burns and scalds, it is advisable to clear heat and detoxify, activate blood circulation to reduce swelling, and promote granulation and relieve pain. The product of the present invention is composed of a large number of drugs such as clearing heat and detoxifying, clearing heat and cooling blood, clearing heat and drying dampness, activating blood circulation and dredging collaterals, dissipating stasis and reducing swelling, removing necrotic tissues and promoting granulation, and astringing pain, so it has good curative effects. And it has obvious inhibitory effects on Staphylococcus aureus, Streptococcus hemolyticus, Pseudomonas aeruginosa, Staphylococcus albus, etc., so it is effective for various surgical infectious diseases.

[0023] The beneficial effects of the present invention are:

[0024] The proportion of the product of the present invention enables various medicinal materials in the medicament to exert the best medicinal effects. Moreover, traditional Chinese medicine and Western medicine interact synergistically, treating both the symptoms and the root causes, restricting each other, reducing toxicity, and being simple and convenient to administer. It can be directly applied to the affected area, significantly improving the healing effect of injuries to human skin, muscle tissue, meridians, bones, etc. after burns and scalds. At the same time, the preparation method of the present invention is simple and easy to operate, suitable for large-scale production, and has wide application value and economic benefits. Brief Description of the Drawings

[0025] The technical solutions of the present application will be further described below with reference to the drawings and embodiments.

[0026] Figure 1 It is the treatment effect diagram of the product of the present invention. Detailed Description of the Embodiments

[0027] It should be noted that, without conflict, the embodiments in the present application and the features in the embodiments can be combined with each other.

[0028] In the description of the present application, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus cannot be understood as a limitation on the protection scope of the present application. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first", "second", etc. may explicitly or implicitly include one or more of such features. In the description of the present invention, unless otherwise stated, the meaning of "a plurality" is two or more.

[0029] In the description of the present application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, and can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood through specific situations.

[0030] The technical solutions of the present application will be described in detail below with reference to the drawings and embodiments.

[0031] Embodiment

[0032] Embodiment 1

[0033] This embodiment provides a compound medicament for treating burns and scalds. The components of the compound medicament are composed of the following raw materials:

[0034] Borneol powder of medicinal materials for clearing heat and relieving pain, antiseptic, promoting granulation and inducing resuscitation;

[0035] Catechu powder of medicinal materials for cooling blood and removing stasis, astringing bleeding, promoting granulation and anti-ulcer;

[0036] Indigo naturalis powder of medicinal materials for clearing heat and detoxifying, activating blood circulation and removing stasis, and removing macules;

[0037] Arnebia euchroma powder of medicinal materials for cooling blood and promoting blood circulation, and also for detoxifying and promoting eruption, and removing macules;

[0038] Calcium carbonate that can prevent edema, reduce inflammation, protect vascular endothelial cells, and promote wound healing. The molecular formula of calcium carbonate is CaCO 3 ;

[0039] Egg white protein powder that is beneficial to the healing of wounds and incisions, and can maintain the normal functions and metabolism of cells. The egg white protein powder is food-grade;

[0040] Refined rapeseed oil with antioxidant properties;

[0041] Organic preservative;

[0042] Specifically, the ratio of borneol powder, catechu powder, indigo naturalis powder, arnebia euchroma powder, calcium carbonate, egg white protein powder, refined rapeseed oil, and organic preservative is = 2:2:2:2:1.5:1:50:0.25.

[0043] The mesh number of borneol powder is 800 mesh, and the catechu powder, indigo naturalis powder, arnebia euchroma powder, and egg white protein powder can also be 800 mesh.

[0044] The catechu powder, indigo naturalis powder, and arnebia euchroma powder are all top-grade medicinal materials. Top-grade Chinese medicinal materials are the highest-grade Chinese medicinal materials with excellent quality and remarkable medicinal effects.

[0045] A preparation method of a compound medicament for treating burns and scalds includes the following steps:

[0046] Step 1: In a sterile environment, put borneol powder, catechu powder, indigo naturalis powder, arnebia euchroma powder, calcium carbonate, egg white protein powder, refined rapeseed oil, and organic preservative in a sterile and water-free container and mix them in proportion for an unlimited time, and just stir well to obtain a mixture;

[0047] Step 2: Pack the mixture into a glass bottle and store it under vacuum seal. When it needs to be used later, take it out and use it.

[0048] Among them, the extraction of calcium carbonate is as follows: First, put quicklime in hot water (tap water, drinking level), place the container in the natural environment (stir the lime water time by time), scoop out the white foam floating on the water surface, and dry it to obtain pure calcium carbonate. The chemical formula of calcium carbonate is CaCO 3 .

[0049] Clinical Example 1:

[0050] Patient Wang, female, 2 years old, was burned when her right palm was placed in the red fire of a coal stove in spring. The junction of the right palm and the right wrist was dry, and the skin discoloration area was about 1.5 square centimeters. There were multiple blisters on the upper part of the palm and the abdominal parts of the five fingers, the epidermal defect, the sweat glands were damaged, and many inflammatory cells infiltrated. The whole hand was swollen and red, and the pain was so severe that she couldn't sleep, and her body had a fever; later, the product of the present invention was used. First, clean the wound surface with iodine tincture and hydrogen peroxide, apply the medicament five times a day. After 5 days, the swelling subsided, the blisters dried and scabbed, the subcutaneous tissue in the discolored part fell off, and the lesion was sunken; continue to clean the wound with iodine tincture and hydrogen peroxide, and continue to give the medicament. After 7 days, the granulation tissue formation in the wound surface was enhanced, granular granulation grew out, the infiltration of inflammatory cells decreased, the epithelialization of the wound defect area was completed, and there were more newly formed blood vessels. The scab on the blister part fell off, and the new skin was slightly red and delicate. Continue to use this medicament. During this period, the patient was pushed and fell to the ground, and the affected area was injured for the second time, showing rupture and bleeding. Disinfect with iodine tincture and continue to use the medicine. After 15 days, the scab fell off, the new skin was pink and delicate. After another 7 days, she recovered completely, the skin was smooth and the color was normal; the interval time and frequency of the above medicine application were determined according to the amount of exudate from the wound surface, and absolute aseptic isolation was not required.

[0051] Example 2

[0052] A compound medicament for treating burns and scalds, and the components of the compound medicament are composed of the following raw materials:

[0053] Borneol powder of Chinese medicinal materials for clearing heat and relieving pain, antiseptic, promoting granulation and inducing resuscitation;

[0054] Catechu powder of Chinese medicinal materials for cooling blood to disperse stasis, astringing to stop bleeding, promoting granulation and anti-ulcer;

[0055] Indigo naturalis powder of Chinese medicinal materials for clearing heat and detoxifying, activating blood circulation to disperse stasis and removing spots;

[0056] Radix arnebiae (L.) DC. powder of Chinese medicinal materials for cooling blood and activating blood circulation, and also for detoxifying and promoting eruption and removing spots;

[0057] Calcium carbonate that can prevent edema, reduce inflammation, protect vascular endothelial cells and promote wound healing. Therefore, calcium carbonate has a regulatory effect on nerve conduction and muscle contraction, maintains the normal excitability of nerves and muscles; reduces vascular permeability and regulates blood coagulation function; can prevent edema, reduce inflammation, protect vascular endothelial cells and promote wound healing;

[0058] Fresh egg white that is beneficial to the healing of wounds and incisions and can maintain the normal functions and metabolism of cells;

[0059] Refined rapeseed oil with antioxidant properties;

[0060] Potassium sorbate;

[0061] Specifically, the ratio of borneol powder, catechu powder, indigo naturalis powder, lithospermum erythrorhizon powder, calcium carbonate, fresh egg white, refined rapeseed oil, and potassium sorbate is 2:2:2:2:1.5:1:50:0.25.

[0062] The mesh number of borneol powder is 1000 mesh, and the catechu powder, indigo naturalis powder, and lithospermum erythrorhizon powder are preferably 1000 mesh.

[0063] Catechu powder, indigo naturalis powder, and lithospermum erythrorhizon powder are all top-grade medicinal materials. Top-grade traditional Chinese medicinal materials are the highest-grade traditional Chinese medicinal materials, with excellent quality and remarkable medicinal effects.

[0064] A preparation method of a compound medicament for treating burns and scalds, comprising the following steps:

[0065] Step 1: In a sterile environment, the dried root of lithospermum erythrorhizon needs to be first soaked in refined rapeseed oil for more than 48 hours, then the lithospermum erythrorhizon root is fished out to obtain lithospermum oil; then borneol powder, catechu powder, indigo naturalis powder, calcium carbonate, fresh egg white, and potassium sorbate are weighed according to the ratio and put into the prepared lithospermum oil, and stirred evenly to obtain a mixture;

[0066] Step 2: The mixture is filled into a glass bottle and stored under vacuum sealing. When it needs to be used later, take it out for use.

[0067] Among them, the extraction of calcium carbonate is as follows: First, put quicklime in hot water (tap water, drinking level), let the container be placed in a natural environment (stir the lime water once and once), fish out the white foam floating on the water surface, and dry it to obtain pure calcium carbonate. The chemical formula of calcium carbonate is CaCO 3 .

[0068] Clinical case two

[0069] Liu XX, male, 4.5 years old. In winter, he was severely scalded on the chest, abdomen and perineum by high-temperature oil, with the injured area reaching over 14%. After 12 months of treatment with western medicine, the wound did not heal, the affected area was still red and swollen, and the subcutaneous muscle tissue was damaged in many places. Pus oozed from the lesion repeatedly, accompanied by high fever from time to time. For a long time, the patient was emaciated, listless and anorexic. Later, this medicament was used. First, the wound surface was cleaned with iodine tincture and hydrogen peroxide. 500 grams of this medicament product was left. A feather or other soft applicator was used to dip the medicine and apply it to the entire burn and scald surface. The medicine was applied at any time every day. After 10 days of use, all the wounds scabbed. After alcohol disinfection, the medicine was continued to be used. After 5 days, the scabs gradually fell off. 300 grams of the medicament was added, and the medicine was reduced to three times a day. After about 15 days, the patient recovered completely. The skin of the original affected area was smooth and flat, with normal color, and the patient regained his spirit.

[0070] Clinical Case 3

[0071] Jiang XX, female, 42 years old. In summer, both feet were scalded by high-temperature hot oil below 5 cm above the ankles, with deep second-degree burns. The skin was red and swollen, with blisters. Accompanied by multiple blisters bursting, the burst areas were white and she couldn't walk. Amoxicillin was taken orally and Zicao oil was used externally, but the symptoms did not relieve. This medicament of the present invention was used three days later. When using, first clean the wound surface with iodine tincture and hydrogen peroxide. A feather or other soft applicator was used to dip the medicine and apply it to the entire burn and scald surface. Since the temperature was high in summer, the medicine was applied more than ten times a day. After 7 days of use, the redness and swelling subsided, most of the blisters healed, and the damaged muscle tissue under the subcutaneous of the dorsal metatarsal part of the foot fell off, and the bone was faintly visible. White granulation tissue could be seen at the edge of the concave part of the lesion. The wound was continuously cleaned with iodine tincture and hydrogen peroxide and the medicine was administered. After another 7 days, the concave part of the lesion began to scab. After alcohol disinfection, this invention was used for another 5 days, and the scabs gradually fell off. The medicine was continued to be used, and alcohol disinfection was occasionally used to relieve itching during this period. After 20 days, the patient recovered completely. The skin of the original affected area was smooth, with normal color. The interval time and frequency of the above medicine application were determined according to the amount of exudate from the wound surface, and absolute aseptic isolation was not required.

[0072] The product of the present invention adopts a combination of traditional Chinese and western medicine. The sticky colloid and extremely astringent components in traditional Chinese medicine can be mixed with the exudate on the wound surface to form a colloid layer. The exudation on the wound surface stops within 24 hours, and the wound surface can heal, dry and scab within 72 hours, forming a scab film covering the wound surface. This not only blocks the recontamination and damage of bacteria in the external air to the wound surface, but also enables the wound surface to breathe through the cracks in the medicine scab; Calcium carbonate in western medicine has a regulatory effect on nerve conduction and muscle contraction, maintaining the normal excitability of nerve and muscle; It reduces the permeability of blood vessels, regulates blood coagulation function; It can prevent edema, reduce inflammation, protect vascular endothelial cells and promote wound healing;

[0073] The combination of traditional Chinese and Western medicine stimulates and cooperates with each other, quickly and significantly inhibiting the exudation of wound body fluid, significantly reducing the loss of water, electrolytes, heat energy and protein, correspondingly reducing the body's overall consumption, and effectively preventing the occurrence of water and electrolyte disorders, hypovolemic shock and hypoproteinemia. After the wound exudation stops, the astringent and bactericidal effects of the medicinal powder can quickly dry and scab the wound, thus preventing the occurrence of wound suppurative infection and systemic infection, protecting the wound early and accelerating the wound healing.

[0074] The active ingredients in the products of the present invention have an enhancing and regulating effect on cellular immunity and humoral immunity, can improve the microcirculation vascular tension and reduce the vascular permeability, continuously generate capillary endothelial cells and fibroblasts, and regenerate and repair new skin on the wound surface in a short period. The treated cases of the products of the present invention include: moderate and severe burns, moderate and severe scalds, moderate steam scalds, moderate metal scalds, severe high-temperature oil scalds. There are many typical burn and scald patients such as those who still do not converge after 12 months of Western medicine treatment, repeatedly discharge purulent fluid, mild electric welding radiation injuries, and moderate scalds in slag cooling ponds, all of whom have been cured. After healing, the skin at the affected area is smooth, without depression, proliferation or melanin deposition.

[0075] Enlightened by the ideal embodiments based on this application above, through the above description, relevant staff can completely make various changes and modifications without departing from the technical idea of this application. The technical scope of this application is not limited to the content in the specification, and its technical scope must be determined according to the scope of the claims.

Claims

1. A compound medicine for treating burns and scalds, characterized in that: The compound medicine composition is composed of the following raw materials: Borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and organic preservatives, wherein the ratio of the borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil and organic preservatives is 2:2:2:2:1.5:1:50:0.25, and the molecular formula of the calcium carbonate is CaCO3.

2. A compound medicine for treating burns and scalds according to claim 1, characterized in that: The mesh size of the borneol powder is 800-1000 meshes.

3. A compound medicine for treating burns and scalds according to claim 2, characterized in that: The catechu powder, indigo powder and lithospermum officinale powder are all special-grade medicinal materials.

4. A compound medicine for treating burns and scalds according to claim 3, characterized in that: The egg white protein powder is food grade.

5. A compound medicine for treating burns and scalds according to any one of claim 4, characterized in that: The organic preservative is potassium sorbate.

6. The method for preparing a compound medicine for treating burns and scalds according to claim 5, characterized in that: The following steps are involved: Step 1, in a sterile environment, borneol powder, catechu powder, indigo powder, lithospermum powder, calcium carbonate, egg white protein powder, refined rapeseed oil, and an organic preservative are mixed according to proportions, and stirred evenly to obtain a mixture; Step 2: Place the mixture into a glass bottle and vacuum seal it for storage.

7. The method for preparing a compound medicine for treating burns and scalds according to claim 6, characterized in that: in, The dried lithospermum root in step 1 is first soaked in refined rapeseed oil for at least 48 hours, and the lithospermum root is removed to obtain lithospermum oil; then borneol powder, catechu powder, indigo powder, calcium carbonate, egg white protein powder, and potassium sorbate are weighed in proportion and put into the lithospermum oil, and stirred thoroughly to obtain a mixture.

8. A compound medicine for treating burns and scalds according to any one of claims 1 to 5, characterized in that: The egg white protein powder is replaced with fresh egg white.

9. A method for preparing a compound medicine for treating burns and scalds according to any one of claims 6-7, characterized in that: The egg white protein powder is replaced with fresh egg white.

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