Composite dietary medicinal and edible base solid beverage and application thereof

Abstract

The invention belongs to the technical field of functional food, and particularly relates to a composite dietary medicinal and edible solid beverage and application thereof.The composite dietary medicinal and edible solid beverage is prepared from 13-32 parts of winter bamboo shoot extract powder, 18-42 parts of seedless pitaya powder, 18-32 parts of banana powder, 8-17 parts of papaya powder, 2.5-9 parts of astragalus membranaceus powder, 0.5-4 parts of ginseng powder and 0.4-3 parts of dendrobium nobile powder. The compound solid beverage disclosed by the invention is prepared from the winter bamboo shoot extract powder, the seedless pitaya powder, the banana powder, the papaya powder, the astragalus membranaceus powder, the ginseng powder, the dendrobium nobile stem powder, the hawthorn powder, the mulberry powder and the sea-buckthorn powder, so that the pH value of a microbial fermentation solution in the intestinal tract of a human body can be reduced, lactic acid producing bacteria including Weissella are increased, and the content of lactic acid is increased; the abundance of Lactobacillus mucilaginosus, Pediococcus and Lactococcus lactis is improved, so that the intestinal health is maintained.

Description

Technical Field

[0001] The invention relates to the technical field of functional foods, in particular to a composite dietary medicine and food homologous solid beverage and application thereof. Background Art

[0002] With the refinement of modern dietary structure and the accelerated pace of life, intestinal health problems are becoming more common. Statistics from the World Health Organization show that about 70% of the world's population has intestinal flora imbalance, which is closely related to obesity, inflammatory bowel disease, metabolic syndrome and other diseases. Lactic acid-producing bacteria are the core beneficial flora of the intestine, and the abundance of related bacterial genera directly affects the intestinal barrier function and metabolic homeostasis.

[0003] Currently, consumers are in urgent need of intestinal health products that are both functional and palatable. Market research shows that 83% of people with intestinal sub-health prefer solid beverages that are mainly natural ingredients and do not require complicated brewing. Traditional solid beverages focus more on vitamin or dietary fiber supplementation, and lack relevant functional and palatable products that directly enhance the beneficial bacteria in the intestines, such as lactic acid-producing bacteria. The application of medicinal and edible matrix in solid beverages can not only improve the palatability of the product, but also have nutritional and medicinal functions. Its dietary fiber and active ingredients can regulate the intestinal flora in both directions.

[0004] Therefore, a new type of solid beverage with composite dietary medicinal and edible homologous base is proposed, which has practical application significance and commercial value. Summary of the invention

[0005] The object of the present invention is to provide a composite dietary medicine and food homologous solid beverage and its application to solve the problems raised in the above background technology.

[0006] To achieve the above object, the present invention provides the following technical scheme: a composite dietary medicine and food homologous solid beverage, wherein the raw material components of the composite dietary medicine and food homologous solid beverage specifically include: 13-32 parts of winter bamboo shoot extract powder, 18-42 parts of seedless pitaya powder, 18-32 parts of banana powder, 8-17 parts of papaya powder, 2.5-9 parts of astragalus powder, 0.5-4 parts of ginseng powder, 0.4-3 parts of dendrobium powder, 0.2-1.5 parts of hawthorn powder, 0.1-0.7 parts of mulberry powder, and 0.1-0.7 parts of sea buckthorn powder;

[0007] The specific preparation method of the composite dietary medicine and food homologous solid beverage is as follows:

[0008] Step 1: Take winter bamboo shoot extract powder, seedless pitaya powder, banana powder, papaya powder, astragalus powder, ginseng powder, dendrobium powder, hawthorn powder, mulberry powder and sea buckthorn powder according to mass proportions, and sterilize the selected powders;

[0009] Step 2: After sterilization, pour the selected powder into the mixer, control the speed to 800-1200 rpm, continue mixing for 3-4 minutes, after mixing completely, pass through a 100-mesh sieve, and take out part of the mixture for sensory inspection. If unevenness is found, continue mixing for 3-5 minutes until it is completely uniform;

[0010] Step 3: Check the color and particle size of the powder for uniformity and agglomeration. Use the Karl Fischer method to determine the moisture content in the powder to ensure that it is less than 5%. Detect microorganisms in the solid powder mixture.

[0011] Step 4: Use food-grade aluminum foil bags or plastic bags, with 5-10 grams of solid beverage powder in each bag, ensuring that the packaging material has good sealing and moisture resistance to extend the shelf life of the product.

[0012] Preferably, the raw material ingredients of the composite dietary medicine and food solid beverage specifically include: 28-32 parts of winter bamboo shoot extract powder, 23-27 parts of seedless pitaya powder, 18-22 parts of banana powder, 8-12 parts of papaya powder, 7-9 parts of astragalus powder, 2-4 parts of ginseng powder, 1-3 parts of dendrobium powder, 0.5-1.5 parts of hawthorn, 0.3-0.6 parts of mulberry powder, and 0.3-0.6 parts of sea buckthorn powder.

[0013] Preferably, the raw material ingredients of the composite dietary medicine and food solid beverage specifically include: 19-21 parts of winter bamboo shoot extract powder, 34-36 parts of seedless pitaya powder, 24-26 parts of banana powder, 9-11 parts of papaya powder, 4-6 parts of astragalus powder, 1.5-2.5 parts of ginseng powder, 0.8-1.2 parts of dendrobium powder, 0.8-1.2 parts of hawthorn powder, 0.3-0.7 parts of mulberry powder, and 0.3-0.7 parts of sea buckthorn powder.

[0014] Preferably, the raw material ingredients of the composite dietary medicine and food solid beverage specifically include: 29-31 parts of winter bamboo shoot extract powder, 24-26 parts of seedless pitaya powder, 19-21 parts of banana powder, 14-16 parts of papaya powder, 4-6 parts of astragalus powder, 1.5-2.5 parts of ginseng powder, 0.8-1.2 parts of dendrobium powder, 0.8-1.2 parts of hawthorn powder, 0.4-0.6 parts of mulberry powder, and 0.4-0.6 parts of sea buckthorn powder.

[0015] Preferably, the raw material ingredients of the composite dietary medicine and food solid beverage specifically include: 23-27 parts of winter bamboo shoot extract powder, 23-27 parts of seedless pitaya powder, 18-22 parts of banana powder, 13-17 parts of papaya powder, 7-9 parts of astragalus powder, 2-4 parts of ginseng powder, 1-3 parts of dendrobium powder, 0.5-1.5 parts of hawthorn powder, 0.3-0.6 parts of mulberry powder, and 0.3-0.6 parts of sea buckthorn powder.

[0016] Preferably, the raw material ingredients of the composite dietary medicine and food solid beverage specifically include: 28-32 parts of winter bamboo shoot extract powder, 18-22 parts of seedless pitaya powder, 28-32 parts of banana powder, 8-12 parts of papaya powder, 4-6 parts of astragalus powder, 1-3 parts of ginseng powder, 0.5-1.5 parts of dendrobium powder, 0.5-1.5 parts of hawthorn powder, 0.3-0.7 parts of mulberry powder, and 0.3-0.7 parts of sea buckthorn powder.

[0017] Preferably, the raw material ingredients of the composite dietary medicine and food solid beverage specifically include: 13-17 parts of winter bamboo shoot extract powder, 38-42 parts of seedless pitaya powder, 28-32 parts of banana powder, 8-12 parts of papaya powder, 2.5-3.5 parts of astragalus powder, 0.5-1.5 parts of ginseng powder, 0.4-0.6 parts of dendrobium powder, 0.2-0.4 parts of hawthorn powder, 0.1-0.15 parts of mulberry powder, and 0.1-0.15 parts of sea buckthorn powder.

[0018] The invention discloses an application of a composite dietary solid beverage with a medicinal and edible homologous base, which helps to reduce the pH value of a microbial fermentation liquid of the human intestine and increase the abundance of various lactic acid-producing bacteria in the fermentation liquid.

[0019] Preferably, the lactic acid producing bacteria include Weissella, Lactobacillus mucinus, Pediococcus and Lactococcus lactis.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] In the present invention, winter bamboo shoot extract, pitaya and banana are rich in dietary fiber, which is beneficial to intestinal health; papaya is rich in digestive enzymes, which is helpful for digestion; astragalus, ginseng and dendrobium have immunoregulatory effects; hawthorn, sea buckthorn and mulberry are rich in antioxidants and can adjust the color and taste of the solid beverage.

[0022] The composite solid beverage prepared by the invention adopts winter bamboo shoot extract powder, seedless pitaya powder, banana powder, papaya powder, astragalus powder, ginseng powder, dendrobium powder, hawthorn powder, mulberry powder and sea buckthorn powder, which can reduce the pH value of human intestinal microbial fermentation liquid, increase the abundance of lactic acid-producing bacteria including Weissella, Lactobacillus mucosa, Pediococcus and Lactococcus lactis, so as to maintain intestinal health. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is the difference diagram of Weissella abundance in fermentation broth;

[0024] Figure 2 This is a graph showing the difference in abundance of Lactobacillus mucilaginosus in the fermentation broth;

[0025] Figure 3 This is the difference diagram of Pediococcus abundance in fermentation broth;

[0026] Figure 4This is a graph showing the difference in abundance of Lactococcus lactis in the fermentation broth. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] In the description of the present invention, it is necessary to understand that the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0029] See also Figure 1-4 , the present invention provides a technical solution:

[0030] A composite dietary medicine and food solid beverage, wherein the raw materials of the composite dietary medicine and food solid beverage specifically include: 13-32 parts of winter bamboo shoot extract powder, 18-42 parts of seedless pitaya powder, 18-32 parts of banana powder, 8-17 parts of papaya powder, 2.5-9 parts of astragalus powder, 0.5-4 parts of ginseng powder, 0.4-3 parts of dendrobium powder, 0.2-1.5 parts of hawthorn powder, 0.1-0.7 parts of mulberry powder, and 0.1-0.7 parts of sea buckthorn powder;

[0031] The specific preparation method of the composite dietary medicine and food homologous solid beverage is as follows:

[0032] Step 1: Take winter bamboo shoot extract powder, seedless pitaya powder, banana powder, papaya powder, astragalus powder, ginseng powder, dendrobium powder, hawthorn powder, mulberry powder and sea buckthorn powder according to mass proportions, and sterilize the selected powders;

[0033] Step 2: After sterilization, pour the selected powder into the mixer, control the speed to 800-1200 rpm, continue mixing for 3-4 minutes, after mixing completely, pass through a 100-mesh sieve, and take out part of the mixture for sensory inspection. If unevenness is found, continue mixing for 3-5 minutes until it is completely uniform;

[0034] Step 3: Check the color and particle size of the powder for uniformity and agglomeration. Use the Karl Fischer method to determine the moisture content in the powder to ensure that it is less than 5%. Detect microorganisms in the solid powder mixture.

[0035] Step 4: Use food-grade aluminum foil bags or plastic bags, with 5-10 grams of solid beverage powder in each bag, ensuring that the packaging material has good sealing and moisture resistance to extend the shelf life of the product.

[0036] The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 28-32 parts of winter bamboo shoot extract powder, 23-27 parts of seedless pitaya powder, 18-22 parts of banana powder, 8-12 parts of papaya powder, 7-9 parts of astragalus powder, 2-4 parts of ginseng powder, 1-3 parts of dendrobium powder, 0.5-1.5 parts of hawthorn, 0.3-0.6 parts of mulberry powder and 0.3-0.6 parts of sea buckthorn powder.

[0037] The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 19-21 parts of winter bamboo shoot extract powder, 34-36 parts of seedless pitaya powder, 24-26 parts of banana powder, 9-11 parts of papaya powder, 4-6 parts of astragalus powder, 1.5-2.5 parts of ginseng powder, 0.8-1.2 parts of dendrobium powder, 0.8-1.2 parts of hawthorn powder, 0.3-0.7 parts of mulberry powder and 0.3-0.7 parts of sea buckthorn powder.

[0038] The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 29-31 parts of winter bamboo shoot extract powder, 24-26 parts of seedless pitaya powder, 19-21 parts of banana powder, 14-16 parts of papaya powder, 4-6 parts of astragalus powder, 1.5-2.5 parts of ginseng powder, 0.8-1.2 parts of dendrobium powder, 0.8-1.2 parts of hawthorn powder, 0.4-0.6 parts of mulberry powder and 0.4-0.6 parts of sea buckthorn powder.

[0039] The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 23-27 parts of winter bamboo shoot extract powder, 23-27 parts of seedless pitaya powder, 18-22 parts of banana powder, 13-17 parts of papaya powder, 7-9 parts of astragalus powder, 2-4 parts of ginseng powder, 1-3 parts of dendrobium powder, 0.5-1.5 parts of hawthorn powder, 0.3-0.6 parts of mulberry powder and 0.3-0.6 parts of sea buckthorn powder.

[0040] The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 28-32 parts of winter bamboo shoot extract powder, 18-22 parts of seedless pitaya powder, 28-32 parts of banana powder, 8-12 parts of papaya powder, 4-6 parts of astragalus powder, 1-3 parts of ginseng powder, 0.5-1.5 parts of dendrobium powder, 0.5-1.5 parts of hawthorn powder, 0.3-0.7 parts of mulberry powder and 0.3-0.7 parts of sea buckthorn powder.

[0041] The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 13-17 parts of winter bamboo shoot extract powder, 38-42 parts of seedless pitaya powder, 28-32 parts of banana powder, 8-12 parts of papaya powder, 2.5-3.5 parts of astragalus powder, 0.5-1.5 parts of ginseng powder, 0.4-0.6 parts of dendrobium powder, 0.2-0.4 parts of hawthorn powder, 0.1-0.15 parts of mulberry powder and 0.1-0.15 parts of sea buckthorn powder.

[0042] The invention discloses an application of a composite dietary solid beverage with a medicinal and edible homologous base, which helps to reduce the pH value of a microbial fermentation liquid of the human intestine and increase the abundance of various lactic acid-producing bacteria in the fermentation liquid.

[0043] The lactic acid producing bacterial genera referred to include Weissella, Lactobacillus mucinosus, Pediococcus and Lactococcus lactis.

[0044] Embodiment 1:

[0045] All raw materials were subjected to in vitro fermentation tests of human intestinal microorganisms:

[0046] Human intestinal microbial collection: Use anaerobic sampling tubes to collect 10g of fresh feces from three healthy adult volunteers (who have not taken antibiotics within 3 months and have no history of gastrointestinal diseases). Immediately take 1g of feces from each volunteer and mix them evenly. Dilute the mixed feces sample with 0.1% L-cysteine ​​PBS at a ratio of 1:10g / mL. Vortex mix and filter with 4 layers of sterile gauze or let stand for 5 minutes. Take the filtrate or supernatant to obtain the intestinal microbial culture. All operations need to be completed within 2 hours after the feces are taken out;

[0047] Fermentation: 1 mL of intestinal microbial culture fluid was mixed with 4 mL of intestinal microbial culture fluid, and 0.1 g of the sample powder to be tested and 100 ul of Oxyrase were added respectively. A negative control group and a prebiotic (oligofructose) positive control group were set up, with 3 replicates in each group. The pH value of each group was adjusted to be consistent. After oscillating and fermenting at 37°C in an anaerobic culture box for 24 hours, the pH value of the fermentation fluid was detected.

[0048] 0.1% L-cysteine ​​PBS: 0.1 g L-cysteine ​​hydrochloride, 0.8 g NaCl, 0.02 g KCl, 0.144 g Na 2 HPO 4 and 0.024 g KH 2 PO 4 Add to 100 mL of purified water.

[0049] Intestinal microbial culture medium: weigh 2.25g KCl, 2.25g NaCl, 0.35g MgSO 4 ·H 2 O, 0.75 g NaHCO3 , 0.4 g L-cysteine ​​HCl·H 2 O, 0.25 g KH 2 PO 4 , 0.25g K 2 HPO 4 , 0.2g bile salt, 0.04g CaCl 2 , 0.0025g FeSO 4 7H 2 O, 1 g arabinogalactan, 0.5 g xylan, 0.5 mL Tween 80 and 2 mL resazurin solution (0.025%, w / v), were prepared into 500 mL intestinal flora growth medium with distilled water and sterilized at 121° C. for 25 min.

[0050] The pH value of the raw materials after fermentation is shown in Table 1:

[0051] Different raw materials, like prebiotic oligofructose, can effectively reduce the pH value of intestinal microbial fermentation broth. The reduction in pH value reflects the increase in the content of short acids in the fermentation broth, and short acids can maintain intestinal health through various mechanisms. The selected raw materials have the potential to be developed into products that are beneficial to intestinal health.

[0052] Table 1 pH value of raw materials after in vitro fermentation

[0053]

[0054]

[0055] Embodiment 2:

[0056] According to the pH value results of raw material fermentation in Example 1, 6 different formulations were prepared with the raw materials involved and all formulations were subjected to in vitro fermentation tests of human intestinal microorganisms:

[0057] Recipe Preparation:

[0058] Weigh 28-32 g of winter bamboo shoot extract powder, 23-27 g of seedless pitaya powder, 18-22 g of banana powder, 8-12 g of papaya powder, 7-9 g of astragalus powder, 2-4 g of ginseng powder, 1-3 g of dendrobium powder, 0.5-1.5 g of hawthorn, 0.3-0.6 g of mulberry powder, and 0.3-0.6 g of sea buckthorn powder, and mix well to prepare formula 1.

[0059] Weigh 19-21 g of winter bamboo shoot extract powder, 34-36 g of seedless pitaya powder, 24-26 g of banana powder, 9-11 g of papaya powder, 4-6 g of astragalus powder, 1.5-2.5 g of ginseng powder, 0.8-1.2 g of dendrobium powder, 0.8-1.2 g of hawthorn, 0.3-0.7 g of mulberry powder, and 0.3-0.7 g of sea buckthorn powder, and mix thoroughly to prepare formula 2.

[0060] Weigh 29-31 g of winter bamboo shoot extract powder, 24-26 g of seedless pitaya powder, 19-21 g of banana powder, 14-16 g of papaya powder, 4-6 g of astragalus powder, 1.5-2.5 g of ginseng powder, 0.8-1.2 g of dendrobium powder, 0.8-1.2 g of hawthorn, 0.4-0.6 g of mulberry powder, and 0.4-0.6 g of sea buckthorn powder, and mix thoroughly to prepare formula 3.

[0061] Weigh 23-27 g of winter bamboo shoot extract powder, 23-27 g of seedless pitaya powder, 18-22 g of banana powder, 13-17 g of papaya powder, 7-9 g of astragalus powder, 2-4 g of ginseng powder, 1-3 g of dendrobium powder, 0.5-1.5 g of hawthorn, 0.3-0.6 g of mulberry powder, and 0.3-0.6 g of sea buckthorn powder, and mix well to prepare formula 4.

[0062] Weigh 28-32 g of winter bamboo shoot extract powder, 18-22 g of seedless pitaya powder, 28-32 g of banana powder, 8-12 g of papaya powder, 4-6 g of astragalus powder, 1-3 g of ginseng powder, 0.5-1.5 g of dendrobium powder, 0.5-1.5 g of hawthorn, 0.3-0.7 g of mulberry powder, and 0.3-0.7 g of sea buckthorn powder, and mix thoroughly to prepare formula 5.

[0063] Weigh 13-17 g of winter bamboo shoot extract powder, 38-42 g of seedless pitaya powder, 28-32 g of banana powder, 8-12 g of papaya powder, 2.5-3.5 g of astragalus powder, 0.5-1.5 g of ginseng powder, 0.4-0.6 g of dendrobium powder, 0.2-0.4 g of hawthorn, 0.1-0.15 g of mulberry powder, and 0.1-0.15 g of sea buckthorn powder, and mix thoroughly to prepare formula 6.

[0064] The reagents and steps of the formula fermentation test are the same as those in Example 1. The pH values ​​of each formula after fermentation are shown in Table 2: Compared with the negative control group, the composite solid beverages prepared by formulas 1-6 in Example 1 of the present invention, under the compounding of winter bamboo shoot extract powder, seedless pitaya powder, banana powder, papaya powder, astragalus powder, ginseng powder, dendrobium powder, hawthorn, mulberry powder and sea buckthorn powder, can effectively reduce the pH value of intestinal microbial fermentation liquid like prebiotic oligofructose. Among them, formula 1 has the largest reduction rate on pH value, followed by formula 3 and formula 2. pH value affects the ecological structure of intestinal microorganisms, and a lower pH value helps to increase the abundance of beneficial bacteria.

[0065] Table 2 pH values ​​after in vitro fermentation of different formulations

[0066]

[0067] Embodiment three:

[0068] The six fermentation broths in Example 2 were used for intestinal microbial sequencing:

[0069] DNA extraction: After the genomic DNA is extracted, the purity is detected by 1% agarose gel electrophoresis.

[0070] PCR amplification: synthesize primers with barcodes, low cycle amplification (consistent number of cycles for each sample), optimize conditions in pre-experiment. Use TransStart Fastpfu enzyme and ABI 9700 instrument, repeat each sample 3 times, mix the products and detect them by 2% agarose gel electrophoresis, cut the gel for recovery and elute.

[0071] Fluorescence quantification: QuantiFluor TM The system detects quantitative PCR products and mixes samples according to the ratio required for sequencing.

[0072] Library construction: PCR was used to add adapter sequences, followed by gel excision, elution and detection, and sodium hydroxide denaturation to produce single-stranded DNA.

[0073] On-chip sequencing: fix DNA fragments to the chip, amplify into clusters by bridge PCR, linearize single strands; synthesize fluorescently labeled dNTPs base by base, scan signals with laser, and count sequences.

[0074] Bioinformatics analysis: After the PEreads obtained by sequencing are split into samples, the paired-end reads are first quality controlled and filtered according to the sequencing quality, and then spliced ​​according to the overlap relationship between the paired-end reads to obtain the optimized data after quality control splicing. Then, the sequence noise reduction method (DADA2 / Deblur, etc.) is used to process the optimized data to obtain the ASV (Amplicon Sequence Variant) representative sequence and abundance information. Based on the ASV representative sequence and abundance information, species difference analysis is performed.

[0075] Sequencing results showed that all six formulas increased the abundance of lactic acid-producing bacteria including Weissella, Lactobacillus mucosa, Pediococcus and Lactococcus lactis ( Figure 1-4 ). Lactic acid-producing bacteria play a key role in maintaining intestinal homeostasis and preventing diseases through acidification of the intestinal environment, metabolic regulation, and immune activation.

[0076] The effect of increasing the abundance of Weissella genus ( Figure 1 ), formula 5>formula 4>formula 2>formula 3>formula 1>formula 6;

[0077] For Lactobacillus mucilaginosus ( Figure 2 ), formula 2>formula 3>formula 1>formula 6>formula 4>formula 5;

[0078] The effect of increasing the abundance of Pediococcus ( Figure 3 ), formula 2>formula 1>formula 3>formula 6>formula 4>formula 5;

[0079] Effect of increasing abundance of Lactococcus lactis ( Figure 4 ), Recipe 3> Recipe 5> Recipe 4> Recipe 1> Recipe 6> Recipe 2.

[0080] In summary of the above embodiments, the present invention uses six formulas of composite solid beverages prepared from winter bamboo shoot extract powder, seedless pitaya powder, banana powder, papaya powder, astragalus powder, ginseng powder, dendrobium powder, hawthorn, mulberry powder and seabuckthorn powder, which can reduce the pH value of human intestinal microbial fermentation liquid, increase the abundance of lactic acid-producing bacteria including Weissella, Lactobacillus mucosa, Pediococcus and Lactococcus lactis, and thus have a positive effect on maintaining intestinal health. Among them, the comprehensive effects of formula 3 and formula 2 are the most preferred.

[0081] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention; therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is limited by the attached claims rather than the above description. Therefore, it is intended to include all changes within the meaning and scope of the equivalent elements of the claims in the present invention, and any figure marks in the claims should not be regarded as limiting the claims involved.

[0082] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A composite dietary medicine and food solid beverage, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 13-32 parts of winter bamboo shoot extract powder, 18-42 parts of seedless pitaya powder, 18-32 parts of banana powder, 8-17 parts of papaya powder, 2.5-9 parts of astragalus powder, 0.5-4 parts of ginseng powder, 0.4-3 parts of dendrobium powder, 0.2-1.5 parts of hawthorn powder, 0.1-0.7 parts of mulberry powder, and 0.1-0.7 parts of sea buckthorn powder; The specific preparation method of the composite dietary medicine and food homologous solid beverage is as follows: Step 1: Take winter bamboo shoot extract powder, seedless pitaya powder, banana powder, papaya powder, astragalus powder, ginseng powder, dendrobium powder, hawthorn powder, mulberry powder and sea buckthorn powder according to mass proportions, and sterilize the selected powders; Step 2: After sterilization, pour the selected powder into the mixer, control the speed to 800-1200 rpm, continue mixing for 3-4 minutes, after mixing completely, pass through a 100-mesh sieve, and take out part of the mixture for sensory inspection. If unevenness is found, continue mixing for 3-5 minutes until it is completely uniform; Step 3: Check the color and particle size of the powder for uniformity and agglomeration. Use the Karl Fischer method to determine the moisture content in the powder to ensure that it is less than 5%. Detect microorganisms in the solid powder mixture. Step 4: Use food-grade aluminum foil bags or plastic bags, with 5-10 grams of solid beverage powder in each bag, ensuring that the packaging material has good sealing and moisture resistance to extend the shelf life of the product.

2. The composite dietary medicine and food homologous solid beverage and its application according to claim 1, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 28-32 parts of winter bamboo shoot extract powder, 23-27 parts of seedless pitaya powder, 18-22 parts of banana powder, 8-12 parts of papaya powder, 7-9 parts of astragalus powder, 2-4 parts of ginseng powder, 1-3 parts of dendrobium powder, 0.5-1.5 parts of hawthorn, 0.3-0.6 parts of mulberry powder and 0.3-0.6 parts of sea buckthorn powder.

3. The composite dietary medicine and food homologous solid beverage and its application according to claim 1, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 19-21 parts of winter bamboo shoot extract powder, 34-36 parts of seedless pitaya powder, 24-26 parts of banana powder, 9-11 parts of papaya powder, 4-6 parts of astragalus powder, 1.5-2.5 parts of ginseng powder, 0.8-1.2 parts of dendrobium powder, 0.8-1.2 parts of hawthorn powder, 0.3-0.7 parts of mulberry powder and 0.3-0.7 parts of sea buckthorn powder.

4. The composite dietary medicine and food homologous solid beverage and its application according to claim 1, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 29-31 parts of winter bamboo shoot extract powder, 24-26 parts of seedless pitaya powder, 19-21 parts of banana powder, 14-16 parts of papaya powder, 4-6 parts of astragalus powder, 1.5-2.5 parts of ginseng powder, 0.8-1.2 parts of dendrobium powder, 0.8-1.2 parts of hawthorn powder, 0.4-0.6 parts of mulberry powder and 0.4-0.6 parts of sea buckthorn powder.

5. The composite dietary medicine and food homologous solid beverage and its application according to claim 1, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 23-27 parts of winter bamboo shoot extract powder, 23-27 parts of seedless pitaya powder, 18-22 parts of banana powder, 13-17 parts of papaya powder, 7-9 parts of astragalus powder, 2-4 parts of ginseng powder, 1-3 parts of dendrobium powder, 0.5-1.5 parts of hawthorn powder, 0.3-0.6 parts of mulberry powder and 0.3-0.6 parts of sea buckthorn powder.

6. The composite dietary medicine and food homologous solid beverage and its application according to claim 1, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 28-32 parts of winter bamboo shoot extract powder, 18-22 parts of seedless pitaya powder, 28-32 parts of banana powder, 8-12 parts of papaya powder, 4-6 parts of astragalus powder, 1-3 parts of ginseng powder, 0.5-1.5 parts of dendrobium powder, 0.5-1.5 parts of hawthorn powder, 0.3-0.7 parts of mulberry powder and 0.3-0.7 parts of sea buckthorn powder.

7. The composite dietary medicine and food homologous solid beverage and its application according to claim 1, characterized in that: The raw materials of the composite dietary medicine and food homologous solid beverage specifically include: 13-17 parts of winter bamboo shoot extract powder, 38-42 parts of seedless pitaya powder, 28-32 parts of banana powder, 8-12 parts of papaya powder, 2.5-3.5 parts of astragalus powder, 0.5-1.5 parts of ginseng powder, 0.4-0.6 parts of dendrobium powder, 0.2-0.4 parts of hawthorn powder, 0.1-0.15 parts of mulberry powder and 0.1-0.15 parts of sea buckthorn powder.

8. An application of the composite dietary medicine and food homologous solid beverage according to any one of claims 1 to 7, characterized in that: The composite dietary medicine and food homologous solid beverage helps to reduce the pH value of the human intestinal microbial fermentation liquid and increase the abundance of various lactic acid-producing bacteria in the fermentation liquid.

9. The use of a composite dietary medicine and food homologous solid beverage according to claim 8, characterized in that: The lactic acid producing bacterial genera referred to include Weissella, Lactobacillus mucinosus, Pediococcus and Lactococcus lactis.

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