Electrode structure and electrode device

Abstract

The invention provides an electrode structure and an electrode device. The electrode structure comprises a sleeve, the sleeve comprises a first rigid section, a flexible transition section and a second rigid section which are sequentially connected in the axial direction, and the flexural modulus of the first rigid section and the flexural modulus of the second rigid section are larger than the flexural modulus of the flexible transition section; the at least one electrode contact is arranged on the outer peripheral wall and / or the inner peripheral wall of the far end of the first rigid section and is used for acquiring information of the target biological tissue and / or regulating and controlling the target biological tissue; the at least one first connecting contact is electrically connected with the electrode contact; the electrode connector is provided with a connecting channel connected with the second rigid section, a second connecting contact matched with the first connecting contact is arranged in the connecting channel, and the electrode contact is electrically connected with the electrode connector through the first connecting contact and the second connecting contact; the connecting channel, the first rigid section, the flexible transition section and the second rigid section form a continuous cavity penetrating through the electrode structure, an interventional instrument can penetrate through the continuous cavity, and the continuous cavity has a guiding and positioning function.

Description

Technical Field

[0001] The present application relates to the technical field of laser ablation, and in particular, to an electrode structure and an electrode device. Background Art

[0002] Laser ablation technology uses a laser to generate high-energy laser light, which is transmitted to the target biological tissue (lesion area) that needs to be ablated through an ablation optical fiber, and uses the thermal effect, photomechanical effect (shock wave) or photochemical effect of the laser to achieve lithotripsy, soft tissue cutting or protein thermal coagulation denaturation. Laser ablation technology is widely used because of its short ablation time and small wound.

[0003] In the related art, the electrode device delivers the interventional instrument used for ablation into the target biological tissue through a sheath. The rigidity of the sheath at each position remains unchanged, making it difficult to balance the overall flexibility and rigidity. In the related art, other electrode structures are also provided to deliver the interventional instrument into the target biological tissue in order to improve the functional richness of the electrode device, resulting in a complex structure of the electrode device and cumbersome operation. Summary of the invention

[0004] In view of the shortcomings of the existing methods, the present application proposes an electrode structure and an electrode device to solve the technical problems existing in the related technology such as unchanged casing rigidity, complex structure or cumbersome operation.

[0005] In a first aspect, an embodiment of the present application provides an electrode structure, including: The sleeve comprises a first rigid section, a flexible transition section and a second rigid section which are sequentially connected along the axial direction, wherein the flexural modulus of the first rigid section and the second rigid section is greater than the flexural modulus of the flexible transition section; At least one electrode contact, disposed on the outer peripheral wall and / or the inner peripheral wall at the distal end of the first rigid segment, for obtaining information of the target biological tissue and / or regulating the target biological tissue; at least one first connection contact, disposed on the peripheral wall of the proximal end of the second rigid segment and electrically connected to the electrode contact; The electrode connector has a connection channel connected to the second rigid section, at least one second connection contact matching the first connection contact is arranged in the connection channel, and the electrode contact is electrically connected to the electrode connector via the first connection contact and the second connection contact; The connecting channel, the first rigid section, the flexible transition section and the second rigid section form a continuous cavity that penetrates the electrode structure. The continuous cavity can be used for the insertion of interventional instruments and has a guiding and positioning function.

[0006] In some possible embodiments, at least one of the first rigid segment and the second rigid segment is a three-layer structure, including a first flexible layer, a hard layer, and a second flexible layer; The first flexible layer is used for contacting with the interventional instrument, and the second flexible layer is used for contacting with the biological tissue during the puncture process.

[0007] In some possible embodiments, the electrode connector is connected to the second rigid segment by a non-detachable connection or a detachable connection.

[0008] In some possible embodiments, the flexural modulus of the first rigid section is smaller than the flexural modulus of the second rigid section.

[0009] In some possible embodiments, the distal end of the first rigid segment is closed or at least partially open.

[0010] In some possible embodiments, the electrode structure further includes: At least one channel structure, which is open at both ends and hollow, and is disposed inside the casing; The inlet of the channel structure is located at the proximal opening of the second rigid segment, the outlet of the channel structure is arranged at at least one of the distal opening of the first rigid segment and the distal peripheral wall, and the outlet of the channel structure is staggered from the position of the electrode contact; The channel structure allows interventional instruments to pass through.

[0011] In some possible embodiments, the electrode contacts include at least two, which are spaced apart and arranged on the outer peripheral wall of the distal end of the first rigid segment; The outlet of the channel structure is arranged between adjacent electrode contacts of the distal peripheral wall of the first rigid section.

[0012] In some possible embodiments, the electrode structure further includes: The sealing component is flexible, and its outer peripheral wall is fixedly connected to the inner peripheral wall at the distal end of the channel structure. It is constructed to deform when an interventional instrument passes through to open the outlet of the channel structure and to seal the outlet of the channel structure without external force.

[0013] In some possible embodiments, the electrode structure further includes at least one of the following: A temperature measuring resistor is arranged on the outer peripheral wall at the far end of the first rigid section; A temperature measuring resistor is arranged on the closed outer end surface at the far end of the first rigid section; The temperature measuring optical fiber is embedded in the outer peripheral wall of the sleeve and extends along the axial direction of the sleeve. The monitoring end of the temperature measuring optical fiber is fixed to the far end of the first rigid section.

[0014] In some possible embodiments, the temperature measuring resistor is disposed on the outer peripheral wall of the distal end of the first rigid section and is located between adjacent electrode contacts.

[0015] In some possible embodiments, the monitoring end of the temperature measuring optical fiber is located between adjacent electrode contacts.

[0016] In a second aspect, an embodiment of the present application further provides an electrode device, comprising an interventional instrument and any electrode structure provided in the first aspect above; The interventional instrument is inserted into the continuous cavity of the electrode structure.

[0017] In some possible embodiments, the interventional device includes at least one of an ablation optical fiber, a temperature measurement optical fiber, an electrode structure, a navigation needle, and a core rod.

[0018] The beneficial technical effects brought about by the technical solution provided by the embodiment of the present application include: The sleeve of the electrode structure in the embodiment of the present application is hollow, and as the probe channel of the interventional instrument, it is a three-section sleeve structure, which includes a first rigid section at both ends, a second rigid section and a flexible transition section in the middle. The appropriate flexural modulus is set according to the position and function, so that the sleeve as a whole has appropriate flexibility and rigidity during the puncture process, thereby improving the puncture efficiency; the sleeve and the electrode connector are electrically connected through the connection contacts, and can be manufactured into a detachable mode to improve the flexibility of the structure. The continuous cavity for the interventional instrument to penetrate integrates the internal channel of the sleeve and the connection channel of the electrode connector, which can compact the structural layout and reduce redundant design. Moreover, the continuous cavity is used as the probe channel of the interventional instrument, and there is no need to repeatedly implant other electrode probes in the sleeve, which can reduce the complexity of operation and thus improve the ablation efficiency. In addition, the electrode structure and the interventional instrument of the present invention adopt a collaborative structural design, and the operation of the interventional instrument and the real-time monitoring are realized synchronously through the channel in the electrode structure, so as to realize the signal of the target area monitored by the electrode structure at any time during the operation of the interventional instrument, thereby improving the accuracy and safety of operation.

[0019] Additional aspects and advantages of the present application will be partially given in the following description, which will become apparent from the following description, or will be understood through the practice of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The above and / or additional aspects and advantages of the present application will become apparent and easily understood from the following description of the embodiments in conjunction with the accompanying drawings, in which: Figure 1 A schematic diagram of an electrode structure provided in an embodiment of the present application; Figure 2 A schematic cross-sectional view of an electrode structure provided in an embodiment of the present application; Figure 3 for Figure 2 A local enlarged schematic diagram of the middle A; Figure 4 A schematic diagram of another electrode structure provided in an embodiment of the present application; Figure 5 A schematic diagram of another electrode structure provided in an embodiment of the present application; Figure 6 A schematic diagram of another electrode structure provided in an embodiment of the present application; Figure 7 A schematic diagram of the structure of an electrode device provided in an embodiment of the present application; Figure 8 A schematic diagram of the structure of another electrode device provided in an embodiment of the present application; Fig. 9 A schematic diagram of the structure of another electrode device provided in an embodiment of the present application; Fig.10 A schematic diagram of the structure of another electrode device provided in an embodiment of the present application; Fig.11 A schematic diagram of the structure of an electrode connector provided in an embodiment of the present application; Fig.12 for Fig.11 Schematic diagram of the structure of the middle electrode connector excluding the conductive ring and the insulating ring.

[0021] Reference numerals: 100- casing; 110- first flexible layer; 120- hard layer; 130- second flexible layer; 200-electrode contacts; 300- waterproof glue; 400-ablation optical fiber; 410-emission end; 500-flexible circuit board; 510-soldering point; 600-electrode connector; 700-channel structure; 800-blocking assembly; 131-channel; 132-fixed part; 1321-first groove; 133-movable part; 1331-second groove; 134-conductive ring; 135-insulating ring; 138-annular guide groove. DETAILED DESCRIPTION

[0022] The embodiments of the present application are described below in conjunction with the drawings in the present application. It should be understood that the implementation methods described below in conjunction with the drawings are exemplary descriptions for explaining the technical solutions of the embodiments of the present application and do not constitute a limitation on the technical solutions of the embodiments of the present application.

[0023] It will be understood by those skilled in the art that, unless specifically stated, the "said" and "the" used herein may also include plural forms. It should be further understood that the wording "including" used in the specification of the present application refers to the presence of the features, integers, steps, operations, elements and / or components, but does not exclude the implementation of other features, information, data, steps, operations, elements, components and / or combinations thereof supported by the present technical field. It should be understood that when we say that an element is "connected" or "coupled" to another element, the element may be directly connected or coupled to the other element, or it may refer to the connection relationship between the element and the other element through an intermediate element. In addition, the "connection" or "coupling" used herein may include wireless connection or wireless coupling. The term "and / or" used herein refers to at least one of the items defined by the term, for example, "A and / or B" may be implemented as "A", or as "B", or as "A and B".

[0024] In order to make the objectives, technical solutions and advantages of the present application clearer, the implementation methods of the present application will be further described in detail below with reference to the accompanying drawings.

[0025] The electrode structure and electrode device provided in this application are intended to solve the above technical problems in related technologies.

[0026] The following is a detailed description of the technical solution of the present application and how the technical solution of the present application solves the above technical problems with specific embodiments. It should be noted that the following implementations can refer to, draw on or combine with each other, and the same terms, similar features and similar implementation steps in different implementations will not be described repeatedly.

[0027] The present application embodiment provides an electrode structure, such as Figure 1-Figure 3 As shown, the electrode structure includes: a sleeve 100, at least one electrode contact 200, at least one first connection contact and an electrode connector.

[0028] The sleeve 100 comprises a first rigid section, a flexible transition section and a second rigid section which are sequentially connected along the axial direction. The flexural modulus of the first rigid section and the second rigid section is greater than the flexural modulus of the flexible transition section.

[0029] At least one electrode contact 200 is disposed on the outer peripheral wall and / or the inner peripheral wall at the distal end of the first rigid segment, and is used to obtain information of the target biological tissue and / or regulate the target biological tissue.

[0030] At least one first connection contact is disposed on the outer peripheral wall of the proximal end of the second rigid segment and is electrically connected to the electrode contact 200 .

[0031] The electrode connector 600 has a connection channel connected to the second rigid section. At least one second connection contact matching the first connection contact is arranged in the connection channel. The electrode contact 200 is electrically connected to the electrode connector 600 via the first connection contact and the second connection contact.

[0032] The connecting channel, the first rigid section, the flexible transition section and the second rigid section form a continuous cavity that penetrates the electrode structure. The continuous cavity can be used for the interventional instrument to penetrate and has a guiding and positioning function. In this embodiment, the sleeve 100 is hollow and serves as the insertion channel of the interventional instrument. It is a three-section sleeve structure, which includes a first rigid section at both ends, a second rigid section and a flexible transition section in the middle. The appropriate flexural modulus is set according to the position and function, so that the sleeve as a whole has appropriate flexibility and rigidity during the puncture process, thereby improving the puncture efficiency; the sleeve 100 is electrically connected to the electrode connector 600 through the connecting contact, and can be manufactured into a detachable mode to improve the flexibility of the structure. The continuous cavity for the interventional instrument to penetrate integrates the internal channel of the sleeve 100 and the connection channel of the electrode connector 600, which can be compactly arranged and reduce redundant design. Moreover, the continuous cavity, as the insertion channel of the interventional instrument, can enrich the function of the electrode device, and use the sleeve 100 and the interventional instrument to work together to bring a variety of possible solutions for the ablation of the target biological tissue. Furthermore, there is no need to repeatedly implant other electrode probes in the cannula 100 , which can reduce the complexity of the operation and further improve the ablation efficiency.

[0033] In this embodiment, the electrode structure has an electrode connector 600, which can monitor the EEG signal simultaneously or at any time when other interventional instruments are working or when the current work is completed.

[0034] In this embodiment, the main body of the electrode structure has varying hardness along the axial direction. The first rigid section has good hardness for penetrating tissues, and the flexible transition section is convenient for fixation on the skull. It can conform to the complex curved paths of biological cavities such as blood vessels and digestive tracts, reducing the risk of tissue damage. The second rigid section has hardness, which is convenient for connection with the electrode connector 600 to ensure the diameter of the continuous cavity, so as to facilitate the penetration of interventional instruments. The design of different hardness can significantly improve the operational flexibility of the electrode.

[0035] Considering that the electrode diameter is relatively small, it is relatively difficult to grasp and insert the interventional instrument during surgery. In this embodiment, adding an electrode connector 600 can improve this problem.

[0036] It should be noted that, in the embodiment of the present application, the proximal end is the end close to the operator, and the distal end is the end away from the operator, that is, the end extending into the target biological tissue.

[0037] Optionally, the target biological tissue may include brain tissue that needs to be ablated by an ablation fiber in an interventional instrument or regulated by the electrode contact 200 .

[0038] Optionally, obtaining information of the target biological tissue includes: obtaining position information, image information, abnormal information, etc. of the target biological tissue, and feeding back to the control system so that the operator can know the position information, image information or abnormal information, etc. of the target biological tissue. For example, the electrode contact 200 can be used to detect brain waves, locate the position of the lesion, and then obtain the position information of the target biological tissue. For another example, abnormal brain signals can be monitored by obtaining abnormal information. Controlling the target biological tissue includes: stimulating the target biological tissue, thermally coagulating the target biological tissue, and other operations.

[0039] Specifically, electrical stimulation is the process of directly changing the membrane potential of neurons and inducing action potentials through the input of stimulation pulse signals, thereby exciting neurons. An external device such as an electrical stimulator or a deep brain stimulator (DBS) is usually used to generate and control the intensity, frequency, and duration of the stimulation pulse signal. During use, the electrode structure needs to be implanted into a specific neural structure or tissue, and then a stimulation pulse signal (e.g., current stimulation) is applied through an external device. The parameters of the stimulation pulse signal (such as current intensity, frequency, and duration) can be adjusted as needed. It is suitable for the treatment of a variety of neurological diseases, such as epilepsy, Parkinson's disease, dystonia, etc. In addition, electrical stimulation can also be used to promote nerve regeneration and repair damaged tissue.

[0040] Optionally, in the embodiment of the present application, the thermal coagulation / ablation operation may include at least one of the following methods: 1. Each electrode contact 200 releases current to act on the lesion area to achieve a thermal coagulation effect.

[0041] 2. Thermal coagulation of the target tissue in the lesion area is performed based on the laser emitted by the optical fiber catheter inserted in the sleeve 100. Generally speaking, thermal coagulation using an optical fiber catheter has a larger thermal coagulation range and is more efficient than thermal coagulation using the electrode contact 200.

[0042] Specifically, thermocoagulation uses the high-frequency oscillation energy generated by radio frequency current to generate heat through friction between the electrode structure and the ions in the tissue, so that the local temperature rises, and then the tissue coagulation and necrosis. It mainly uses external devices such as radio frequency instruments or high-frequency electric knives to generate radio frequency current (high-frequency current) and conduct the current to the target biological tissue through the electrode structure. Usually, the high-frequency current is conducted to the target tissue by piercing electrodes or needle electrodes through the skin. During the operation, the doctor will adjust the intensity and action time of the current according to the resistance and temperature feedback of the tissue. It is mainly used to treat painful diseases such as trigeminal neuralgia, sciatica, etc. In addition, thermocoagulation can also be used for hemostasis, tissue cutting and ablation in surgical operations. Optionally, the number of electrode contacts 200 can include multiple, such as 8, 10, 12, 14, 16 or 18.

[0043] Optionally, the electrode contact 200 may be annular or semi-annular, and circumferentially disposed outside the sleeve 100 .

[0044] In some possible embodiments, Figure 3 As shown, the flexible circuit board 500 is attached to the wall of the sleeve 100 , and the flexible circuit board 500 has a plurality of solder joints 510 , and a plurality of electrode contacts 200 are soldered to each solder joint 510 in a one-to-one correspondence.

[0045] Optionally, the thickness of the flexible circuit board 500 is between 0.05 mm and 1 mm (including 0.05 mm and 1 mm).

[0046] In some possible embodiments, Figure 3 As shown, the electrode structure further includes: waterproof glue 300. The waterproof glue 300 covers the exposed surface of the flexible circuit board 500, protects the flexible circuit board 500, and improves the circuit reliability of the electrode structure.

[0047] When the present application is in the first state, the interventional instrument penetrates into the axial passage from the opening communicating with the outside world. To this end, the present application also provides the following embodiments.

[0048] In some possible embodiments, the electrode connector 600 is connected to the second rigid section in a non-detachable manner.

[0049] In this embodiment, the electrode connector 600 is fixedly connected to the second rigid segment and cannot be disassembled. As an integrated structure, the stability of the continuous cavity can be improved. For example, at least part of the channel of the electrode connector is fixedly and inseparablely connected to the second rigid segment in the form of sleeve or docking to achieve electrical connection. Further, if it is sleeved, the electrical connection method between the second rigid segment and the electrode connector 600 can be that the proximal end of the second rigid segment is provided with a connection contact corresponding to the channel one by one; if it is docked, the proximal opening of the second rigid segment and the channel are fixedly connected in a relatively aligned manner or partially overlapped manner, and the guide wire in the second rigid segment is connected to the electric control unit of the electrode connector 600 to achieve electrical connection.

[0050] In some possible embodiments, the electrode connector 600 is detachably connected to the second rigid section.

[0051] In this embodiment, the electrode connector 600 is detachably connected to the second rigid segment. As a split structure, the electrode connector 600 of different specifications and the sleeve 100 of different specifications can be adjusted according to actual conditions, and the flexibility is strong. The electrode connector 600 and the sleeve 100 can be detachably connected: for example, at least part of the channel of the electrode connector 600 is electrically connected to the second rigid segment in the form of sleeve connection or docking; the detachable method can be that the proximal end of the second rigid segment is plugged into the channel, or the electrode connector 600 is connected to the second rigid segment in an open and closed form, or in other threaded forms.

[0052] In some possible embodiments, the flexural modulus of the first rigid section is smaller than the flexural modulus of the second rigid section.

[0053] In this embodiment, the flexural modulus of the first rigid segment is smaller than that of the second rigid segment, but larger than that of the transition segment. This enables the first rigid segment to have a certain rigidity to guide the target tissue when implanted as a head end, while also having a certain flexibility to reduce the mechanical stress during implantation into the target tissue, thereby reducing damage to the target tissue.

[0054] When the present application is in the second state, the opening is set inside the electrode connector and cannot be connected to the outside. In order to achieve the insertion of the interventional instrument, the present application also provides the following embodiments: 1. The electrode connector 600 and the second rigid segment are separable. Furthermore, the second rigid segment can be taken out of the electrode connector 600, and the interventional instrument is inserted from the proximal end of the second rigid segment. The separable manner is not limited to the opening and closing form, the plug-in form, the threaded form, etc.

[0055] 2. The electrode connector 600 and the second rigid segment may also be inseparable. For example, the electrode connector 600 is in an open-close form, and at least a portion of the lower half cross-section of the channel of the electrode connector 600 is fixedly connected to the proximal end of the second rigid segment. The proximal opening of the second rigid segment and the opening of the electrode connector 600 are at a certain distance from each other. If the interventional device has a certain flexibility, the interventional device can be inserted therethrough.

[0056] Optionally, in one embodiment of the present application, Fig.11 As shown, the electrode connector 600 includes a fixed portion 132 and a movable portion 133 .

[0057] The fixed portion 132 is rotatably connected to the movable portion 133 . The fixed portion 132 is provided with a first groove 1321 , and the movable portion 133 is correspondingly provided with a second groove 1331 . When the movable portion 133 rotates to an opening and closing angle of zero relative to the fixed portion 132 , the first groove 1321 and the second groove 1331 form a channel 131 .

[0058] A plurality of conductive rings 134 and a plurality of insulating rings 135 are disposed in the first slot 1321 . The plurality of conductive rings 134 and the plurality of insulating rings 135 are alternately arranged along the extension direction of the first slot 1321 . The conductive rings 134 and the insulating rings 135 each extend along the circumference of the first slot 1321 .

[0059] In the embodiment of the present application, the movable part 133 and the fixed part 132 of the electrode connector 600 can be connected together through a rotating shaft, and the opening and closing angle of the movable part 133 relative to the fixed part 132 includes: 0-90°. When the movable part 133 rotates to an opening and closing angle of zero relative to the fixed part 132, the movable part 133 and the fixed part 132 are in a closed state, and the first groove 1321 and the second groove 1331 form a channel 131, and the channel 131 is connected to the first support tube 11. At this time, the interventional instrument 2 can enter the first support tube 11 through the channel 131, so that the interventional instrument 2 such as the ablation optical fiber can be used in subsequent laser ablation surgery. When the rotation opening and closing angle of the movable part 133 relative to the fixed part 132 is greater than zero, the movable part 133 and the fixed part 132 are in an open state, and the first support tube 11 can be installed in the channel 131, or the first support tube 11 can be removed from the channel 131.

[0060] In the embodiment of the present application, a plurality of conductive rings 134 and a plurality of insulating rings 135 are provided in the second groove 1331; along the extension direction of the second groove 1331, the plurality of conductive rings 134 and the plurality of insulating rings 135 are alternately arranged; the conductive rings 134 and the insulating rings 135 each extend along the circumference of the second groove 1331. When the movable portion 133 rotates to an opening and closing angle of zero relative to the fixed portion 132, the first groove 1321 and the second groove 1331 form a channel 131, and the plurality of conductive rings 134 and the plurality of insulating rings 135 in the first groove 1321 correspond to the plurality of conductive rings 134 and the plurality of insulating rings 135 in the second groove 1331 one by one, so that the conductive rings 134 and the insulating rings 135 each extend along the circumference of the channel 131. The conductive ring 134 is made of metal or the like for conducting electricity; the insulating ring 135 is made of silicone or the like, and the insulating ring 135 is used for sealing and isolating adjacent conductive rings 134. The electric control unit in the electrode connector 600 is electrically connected to the multiple conductive rings 134 in the first slot 1321 and the multiple conductive rings 134 in the second slot 1331. It should be noted that in the present application, the conductive ring 134 and the insulating ring 135 can be arranged only in the first slot 1321, and the conductive ring 134 and the insulating ring 135 are not arranged in the second slot 1331.

[0061] Optionally, in one embodiment of the present application, Figure 11-12As shown, an annular guide groove 138 is provided in the first groove 1321 and the second groove 1331 , and a plurality of conductive rings 134 and a plurality of insulating rings 135 are slidably disposed in the annular guide groove 138 of the first groove 1321 and the second groove 1331 .

[0062] In the embodiments of the present application, Figure 11-12 As shown, a plurality of conductive rings 134 and insulating rings 135 can be slidably embedded in an annular guide groove 138 formed by a first groove 1321 and a second groove 1331, for example, by means of snap connection, interference fit, standing connection, etc., so that the electrode connector 600 has dynamic adaptability, and by adjusting the axial spacing between the conductive ring 134 and the insulating ring 135, the spacing specification of the proximal contact of the first support tube 11 can be matched, thereby achieving rapid adaptation with electrode modules with different contact specifications.

[0063] In some possible embodiments, Figure 1 As shown, the distal end of the first rigid section is closed.

[0064] In this embodiment, the distal end of the first rigid section is closed and can be directly used as a puncture end, thereby improving the convenience of puncture.

[0065] In some possible embodiments, at least a portion of the distal end of the first rigid segment is open.

[0066] In this embodiment, at least a portion of the distal end of the first rigid segment is open, so that when the distal end of the first rigid segment approaches the target biological tissue, the distal end of the interventional instrument extends beyond the distal end of the first rigid segment and continues to perform short-distance puncture to reach the target biological tissue with a more complex structure, thereby minimizing the damage of the cannula 100 to the target biological tissue.

[0067] like Figure 4 and Figure 8 As shown, the distal end of the first rigid section is an opening, which facilitates the interventional instrument (such as the ablation optical fiber 400 ) to pass through the distal end of the sheath 100 .

[0068] In some possible embodiments, Figure 5 As shown, the electrode structure further includes: at least one channel structure 700 .

[0069] The channel structure 700 is open at both ends and hollow, and is disposed inside the sleeve 100 .

[0070] The entrance of the channel structure 700 is located at the proximal opening of the second rigid segment, and the exit of the channel structure 700 is arranged at at least one of the distal opening of the second rigid segment and the distal peripheral wall. The exit of the channel structure 700 is staggered with the position of the electrode contact 200.

[0071] The channel structure 700 allows interventional instruments to pass through.

[0072] In this embodiment, a plurality of independent channel structures 700 are arranged inside the cannula 100, and each channel structure 700 can allow one or more interventional instruments to pass through, so that the distal end of the interventional instrument reaches the target biological tissue for corresponding ablation and other treatments. The channels of the multiple interventional instruments are independent of each other and do not interfere with each other, which can improve the reliability of the interventional instruments. On the other hand, the non-interference channel design enables each interventional instrument to accurately maintain its own functional parameters, and will not cause functional disorders due to abnormal fluctuations of adjacent interventional instruments, thereby providing double protection for the accuracy and safety of medical operations.

[0073] In some possible embodiments, Figure 1 As shown, the electrode contacts 200 include at least two electrode contacts 200 that are spaced apart and disposed on the outer peripheral wall of the distal end of the first rigid section.

[0074] The outlet of the channel structure 700 is disposed between adjacent electrode contacts 200 on the distal peripheral wall of the first rigid section.

[0075] In this embodiment, a plurality of electrode contacts 200 are arranged at circumferential intervals on the outer peripheral wall of the distal end of the first rigid section, and acquire information from each other for analysis and processing to obtain information at the target biological tissue. The outlet of the channel structure 700 is arranged between adjacent electrode contacts 200, and is staggered with the electrode contacts 200 so as not to affect each other.

[0076] Optionally, the interventional device includes an ablation optical fiber 400, and the types of ablation optical fibers 400 passing through at least two channel structures 700 are different. For example, one ablation optical fiber 400 uses a 980-nanometer semiconductor laser, which can generate high-power lasers. The laser unit itself has heat dissipation, which can ensure long-term stable output. Another ablation optical fiber 400 uses a 1064-nanometer Nd:YAG (the laser crystal material is yttrium doped aluminum oxide) laser, which can generate high-power lasers. Other lasers can also generate other forms of lasers, which are not limited here.

[0077] In some possible embodiments, Figure 5 As shown, the electrode structure also includes: a sealing component 800.

[0078] The blocking component 800 is flexible, and its outer peripheral wall is fixedly connected to the inner peripheral wall at the distal end of the channel structure 700. It is constructed to deform when an interventional instrument passes through to open the outlet of the channel structure 700 and block the outlet of the channel structure 700 without external force.

[0079] In this embodiment, the blocking component 800 can block the distal opening of the channel structure 700 without external force, so as to prevent foreign matter from entering the channel structure 700 when the channel structure 700 is not in use, thereby blocking the channel structure 700 and preventing the channel structure 700 from affecting the normal puncture operation. When the interventional instrument passes through, the blocking component 800 can be deformed under the action of the distal end of the interventional instrument and open the outlet of the channel structure 700, so that the distal end of the interventional instrument passes through to perform corresponding ablation and other operations.

[0080] In some possible embodiments, the electrode structure further includes a temperature measuring resistor (not shown in the figure) disposed on the outer peripheral wall of the distal end of the first rigid section.

[0081] In this embodiment, the distal end of the sleeve 100 is open, and the temperature measuring resistor can be arranged on the outer peripheral wall of the distal end of the first rigid section to perform temperature measurement on the target biological tissue contacted by the outer peripheral wall of the first rigid section.

[0082] In some possible embodiments, the electrode structure further includes a temperature measuring resistor disposed on a closed outer end surface at the distal end of the first rigid section.

[0083] In this embodiment, the distal end of the first rigid section is closed, and a temperature measuring resistor can be disposed on the closed outer end surface of the distal end of the first rigid section to perform a temperature measurement operation on the target biological tissue contacted by the distal end of the first rigid section during puncture.

[0084] Optionally, the temperature measuring resistor can share a circuit with the electrode contact 200 and be controlled separately, which can simplify the circuit structure.

[0085] In some possible embodiments, the electrode structure further includes a temperature measuring optical fiber (not shown in the figure), which is embedded in the outer peripheral wall of the sleeve 100 and extends axially along the sleeve 100. The monitoring end 410 of the temperature measuring optical fiber is fixed to the distal end of the first rigid section.

[0086] In this embodiment, the temperature measuring optical fiber is embedded and fixed to the outer peripheral wall of the cannula 100 along the axial direction, and can be synchronously punctured into the body with the cannula 100, and the distal end reaches the target biological tissue to perform the temperature measurement operation. In addition, the temperature measuring optical fiber does not occupy the radial space of the cannula 100, ensuring the normal puncture operation of the cannula 100.

[0087] In some possible embodiments, the temperature measuring resistor is disposed on the outer peripheral wall of the distal end of the first rigid segment and is located between adjacent electrode contacts 200 .

[0088] In this embodiment, the adjacent electrode contacts 200 can perform a thermosetting operation, and the temperature measuring resistor can obtain the temperature information between the two thermosetting locations and perform information processing to make the measured temperature closer to the temperature of the thermosetting center, thereby making the temperature measurement more accurate.

[0089] In some possible embodiments, the monitoring end 410 of the temperature measuring optical fiber is located between adjacent electrode contacts 200 .

[0090] In this embodiment, the adjacent electrode contacts 200 can perform a thermosetting operation, and the temperature measuring resistor can obtain the temperature information between the two thermosetting locations and perform information processing to make the measured temperature closer to the temperature of the thermosetting center, thereby making the temperature measurement more accurate.

[0091] In some possible embodiments, the electrode contacts 200 are annular and are arranged at intervals in sequence along the axial direction of the sleeve 100. Between adjacent electrode contacts 200, along the circumference of the sleeve 100, the outlet positions of the temperature measuring resistor and the channel structure are arranged at intervals without affecting each other. Moreover, there is a certain length space between adjacent electrode contacts 200, and the output end 410 of the ablation optical fiber 400 also has a certain length, which can correspond to the length space between multiple adjacent electrode contacts 200. By adjusting the insertion position of the ablation optical fiber 400, the ablation position of the ablation optical fiber 400 can be adjusted.

[0092] In some embodiments, Figure 6 As shown, at least one of the first rigid segment and the second rigid segment is a three-layer structure, including a first flexible layer 110, a hard layer 120, and a second flexible layer 130. The first flexible layer 110 is used to contact the interventional instrument, and the second flexible layer 130 is used to contact the biological tissue during the puncture process.

[0093] In this embodiment, at least part of the tube wall of the cannula 100 is composed of a three-layer structure, namely, a soft first flexible layer 110 and a second flexible layer 130 and a hard layer 120 sandwiched therein. The first flexible layer 110 is an inner layer. When the interventional device enters the cannula 100, the first flexible layer 110 can play a buffering role to prevent the interventional device from being damaged by friction or collision with the tube wall of the cannula 100 during the insertion of the cannula 100. The hard layer 120 is an intermediate layer to ensure that the cannula 100 has the rigidity to be implanted in the target biological tissue, so that the puncture process proceeds smoothly. The second flexible layer 130 is an outer layer. During the puncture process, the second flexible layer 130 can reduce the friction between the cannula 100 and the biological tissue and reduce the damage to the biological tissue on the puncture path. Moreover, the second flexible layer 130 has better biocompatibility and can be implanted in the target tissue for a long time. Therefore, the cannula 100 provided in the embodiment of the present application can improve the reliability of the electrode structure, improve the puncture efficiency, and reduce the puncture damage.

[0094] However, the flexible transition section mainly plays a transition role, with a guiding role as a secondary role, and its specific structure may be different from the first rigid section and the second rigid section.

[0095] Optionally, the materials of the electrode structures are all magnetically compatible materials, which facilitates magnetic resonance imaging examinations.

[0096] In some possible embodiments, at least one electrode contact 200 is disposed on the inner peripheral wall of the distal end of the first flexible layer 110 .

[0097] In this embodiment, the electrode contact 200 is integrated into the inner peripheral wall of the distal end of the first flexible layer 110, and arrives at the target biological tissue synchronously with the first flexible layer 110 during the process of the sleeve 100 probing into the target biological tissue, thereby performing operations such as obtaining information of the target biological tissue and performing heat treatment on the target biological tissue.

[0098] Specifically, during the puncture process, part of the biological tissue may enter the distal opening of the cannula 100, and relevant operations are performed on the target biological tissue that may enter the opening of the cannula 100 during the puncture process, namely, obtaining information of the target biological tissue, performing heat treatment on the target biological tissue, and other operations.

[0099] Optionally, the target biological tissue is subjected to heat treatment, including: stimulating the target biological tissue, thermally coagulating the target biological tissue, and the like.

[0100] In some possible embodiments, Figure 6 As shown, at least one electrode contact 200 is disposed on the distal peripheral wall of the second flexible layer 130 .

[0101] In this embodiment, the electrode contact 200 is disposed on the distal peripheral wall of the second flexible layer 130 and contacts the target biological tissue, thereby obtaining information of the target biological tissue and performing heat treatment on the target biological tissue.

[0102] In some possible embodiments, Figure 6 As shown, there are at least two electrode contacts 200, which are arranged on the first flexible layer 110 or the second flexible layer 130 at an axial spacing along the sleeve 100. The information obtained by the multiple electrode contacts 200 can be analyzed and processed to obtain specific position information or other information of the target biological tissue.

[0103] In some possible embodiments, the temperature measuring resistor is disposed on the inner peripheral wall of the distal end of the first flexible layer 110 .

[0104] In this embodiment, the temperature measuring resistor is disposed on the inner peripheral wall of the distal end of the first flexible layer 110 to perform a temperature measurement operation on the target biological tissue that may enter the opening of the sleeve 100 during the puncture process.

[0105] In some possible embodiments, the temperature measuring resistor is disposed on the distal outer peripheral wall of the second flexible layer 130 .

[0106] In this embodiment, the temperature measuring resistor is disposed on the outer peripheral wall of the distal end of the second flexible layer 130 and is in contact with the target biological tissue, thereby performing a temperature measurement operation on the target biological tissue.

[0107] In some possible embodiments, the temperature measuring optical fiber is embedded in the outer peripheral wall of the second flexible layer 130 and extends along the axial direction of the sleeve 100 . The monitoring end 410 of the temperature measuring optical fiber is fixed to the distal end of the second flexible layer 130 .

[0108] In this embodiment, the temperature measuring optical fiber is embedded in the axial direction and fixed to the outer peripheral wall of the second flexible layer 130, and can be synchronously punctured into the body with the cannula 100, and the distal end reaches the target biological tissue to perform a temperature measurement operation. In addition, the temperature measuring optical fiber does not occupy the radial space of the cannula 100, ensuring the normal puncture operation of the cannula 100.

[0109] Moreover, the use of optical fiber for temperature measurement can better match the space inside the sleeve 100, and is also easy to install and probe into the target biological tissue. In addition, the temperature measurement optical fiber and the ablation optical fiber 400 have similar communication principles, and are also convenient for information exchange with the control host.

[0110] In some possible embodiments, the interventional instrument includes an image acquisition component, and an image acquisition end of the image acquisition component faces the lesion area.

[0111] In this embodiment, the acquisition end of the image acquisition component has a device for acquiring images of the target tissue, such as a micro-camera. The acquisition end is directed toward the lesion area, and the acquired image information is transmitted to the human-computer interaction interface and displayed to the operator, so that the operator or the computer program can monitor the image of the target tissue in real time and determine whether the ablation is in place, which is conducive to improving the efficiency and accuracy of ablation.

[0112] Based on the same inventive concept, an embodiment of the present application further provides an electrode device, including an interventional instrument and an electrode structure as provided in any of the above embodiments.

[0113] like Figure 7 or Figure 8 As shown, the interventional instrument is inserted into the continuous cavity of the electrode structure.

[0114] In this embodiment, the electrode structure used is similar to that of the above-mentioned embodiment, and will not be described here. The sleeve 100 in this embodiment is hollow and serves as the probe channel of the interventional instrument. It is a three-section sleeve structure, which includes a first rigid section at both ends, a second rigid section, and a flexible transition section in the middle. The appropriate flexural modulus is set according to the position and function, so that the sleeve as a whole has appropriate flexibility and rigidity during the puncture process, thereby improving the puncture efficiency; the sleeve 100 is electrically connected to the electrode connector 600 through the connection contact, and can be manufactured into a detachable mode to improve the flexibility of the structure. The continuous cavity for the interventional instrument to penetrate integrates the internal channel of the sleeve 100 and the connection channel of the electrode connector 600, which can be compactly arranged and reduce redundant design. Moreover, the continuous cavity, as the probe channel of the interventional instrument, can enrich the function of the electrode device, and use the sleeve 100 and the interventional instrument to work together to bring multiple possible solutions for the ablation of the target biological tissue. Moreover, there is no need to repeatedly implant other electrode probes in the sleeve 100, which can reduce the complexity of the operation and thus improve the ablation efficiency.

[0115] The working principle of the embodiment of the present application includes: there are multiple suspicious areas in the biological tissue, and electrode structures can be implanted in the suspicious areas to collect information, such as collecting and detecting brain waves, and then the specific location of the lesion area is obtained through comprehensive analysis of the information fed back by the multiple electrode structures. If a clear lesion target is known, a suitable treatment plan can be selected according to the properties (shape, size, etc.) of the lesion area. For example, if the lesion area is small, the electrode contact 200 can be used for thermal coagulation loss.

[0116] If the lesion area is large, considering that the scope of damage caused by electrode thermal coagulation is small, it is difficult to completely cover the lesion area. In the related technology, a secondary operation is required, that is, other operations are used to treat the lesion area. It may be necessary to perform minimally invasive surgery again, which is complicated and inefficient, and also increases the risk of infection. However, in the embodiment of the present application, the ablation optical fiber 400 can pass through the cannula 100 to reach the lesion area, and laser ablation is performed, eliminating the need for a secondary operation, which is simple and efficient to operate, does not require a new wound, and can reduce the risk of infection.

[0117] Furthermore, in the process of laser ablation treatment in combination with the ablation optical fiber 400, the laser ablation optical fiber 400 of suitable specifications can be selected according to the characteristics of the target biological tissue. The ablation optical fiber 400 can be divided into different specifications according to the regional length of the optical fiber output end 410 (or the diffusion end), such as 4 mm, 10 mm or 15 mm. During laser ablation, light is emitted from the gap between each electrode contact 200 and absorbed by the target biological tissue to achieve ablation.

[0118] In addition, when the target biological tissue is in the shape of a long strip, ablation can be performed by withdrawing the needle. Specifically, if a closed cannula 100 is used, after ablation of a portion of the target biological tissue, the cannula 100 and the ablation optical fiber 400 are synchronously withdrawn for a distance, and ablation is continued, thereby completely ablating the long strip of target biological tissue. If an unclosed cannula 100 is used, the cannula 100 can be withdrawn, and the ablation optical fiber 400 can be kept stationary, so that the target biological tissue can be completely exposed to the output end 410 of the ablation optical fiber 400, making the ablation more thorough and reducing the ablation time. Alternatively, the cannula 100 can be fixed and the ablation optical fiber 400 can be withdrawn alone, depending on the actual situation.

[0119] In some possible embodiments, the interventional device includes: at least one of an ablation optical fiber 400, a temperature measurement optical fiber, an electrode structure, a navigation needle, and a core rod.

[0120] In this embodiment, the ablation optical fiber 400 can perform an ablation operation on the target biological tissue, and the temperature measuring optical fiber can perform a temperature measuring operation on the target biological tissue. Among the electrode structures of different sizes, one electrode structure can be sleeved in the sleeve 100 of another electrode structure to perform a segmented puncture operation, which can reduce the difficulty of puncture and improve the adaptability of complex puncture paths. For example, a smaller diameter electrode structure can be used to puncture deep into the brain to reduce damage and achieve a deeper puncture depth. For another example, a navigation needle can be used to guide the electrode structure into the target biological tissue.

[0121] Alternatively, if Fig. 9 and Fig.10 As shown, the electrode device also includes: an electrode connector 600, which is used to connect to other devices to transmit the EEG signal to the EEG machine for corresponding information processing.

[0122] Optionally, the ablation optical fiber 400 may be overheated during the process of transmitting laser light, and it is necessary to cool the ablation optical fiber 400. A tubular structure may be arranged outside the sleeve 100, and a cooling circuit may be formed between the sleeve 100 and the tubular structure, which is connected to a cooler for circulating a cooling medium, thereby achieving the effect of cooling the ablation optical fiber 400.

[0123] Optionally, two channel structures 700 may be connected to form a cooling circuit for circulating a cooling medium, thereby cooling the ablation optical fiber 400. This embodiment only requires one sleeve 100, which can improve the space utilization inside the sleeve 100, reduce the radial size of the sleeve 100 to a certain extent, and thus reduce the wound area, bleeding volume or infection risk during the ablation process.

[0124] Optionally, the electrode device is also connected to an external device and a control host, and the external device can receive the digital image information of the user. The control host can complete the patient file creation and three-dimensional modeling based on the digital image information provided by the magnetic resonance imaging device, and perform multi-modal three-dimensional modeling based on the digital image information to obtain a three-dimensional model of the user.

[0125] Optionally, the digital image information may be manually input, or acquired by a camera device and transmitted to the control host.

[0126] Alternatively, the three-dimensional model may be obtained based on images measured by computer tomography or magnetic resonance imaging.

[0127] Optionally, the interventional device provided in the embodiment of the present application can obtain real-time temperature information in real time, and obtain a three-dimensional temperature cloud map of the real-time temperature information based on the three-dimensional model. Moreover, the real-time temperature information can be output to an external device, and the three-dimensional temperature cloud map can be displayed in real time using a human-computer interaction interface to help technicians who perform ablation obtain temperature information of the lesion area in real time and reduce the risk of ablation. Moreover, when technicians judge the ablation results through the temperature display, the three-dimensional stereoscopic display helps technicians view the results of ablation in all directions, rather than just looking at the results in the scanning direction, making the judgment of the ablation results more accurate.

[0128] Optionally, the real-time acquisition of the real-time temperature information may be achieved by using the following technologies: for example, using parallel scanning technology to acquire the real-time temperature information, using stereo scanning technology to acquire the real-time temperature information, or using thin-layer scanning technology to acquire the real-time temperature information.

[0129] Optionally, the external device includes a magnetic resonance imaging device, a human-computer interaction interface, a power module and other peripheral interfaces.

[0130] Optionally, the control host can control the laser, cooler and electrode device according to the information fed back by the human-machine interaction interface, control the generation of various lasers, power regulation, and drive and control the cooler to control the temperature of the ablation optical fiber 130.

[0131] Optionally, the human-machine interface is used in conjunction with the control host, using a combination of 2 24-inch touch screens + 1 10-inch touch screen + physical buttons + working indicator lights. It also provides input methods such as touch screen, mouse, keyboard, and physical knob. The emergency stop control switch can shut down each functional component, but it will not shut down the human-machine interface.

[0132] Optionally, in order to improve the stability and safety of the system, the control interface of the laser and the cooler is provided with two sets of foot switches to control the emission of the laser. When one set fails, the other set can be used for control.

[0133] Optionally, water cooling can be used in the embodiments of the present application. The cold source is stable, the effect is good, and the preparation cost is low. The structure includes a peristaltic pump, a coolant tank, a waste liquid tank, a cooling pipe, and a coolant. A single-channel system can be used to prevent the occurrence of circulating reflux pollution. The coolant tank is equipped with a heater, a temperature sensor, and a solution sensor. When the cooling component is working, the heating module will heat the coolant in the coolant tank to a suitable temperature. Detected by the temperature sensor. After that, the peristaltic pump starts working and transports the coolant to the laser ablation device to form a cooling circuit. Then it enters the waste liquid bottle through the return pipe, and there will be a flow sensor in front of the waste liquid bottle to confirm whether the coolant is refluxed normally. The solution sensor on the coolant tank can detect the solution condition in the coolant tank. When the solution is insufficient, an alarm signal will be issued to require the coolant to be replaced.

[0134] Optionally, other peripheral interfaces include but are not limited to a USB (Universal Serial Bus) interface, a security switch interface, a network cable, an optical drive, and the like.

[0135] Optionally, the electrode device can be fixed to the patient's skull via a fixing assembly, which is used to fix and guide the sleeve 100 of the electrode device so that the sleeve 100 can accurately reach the lesion location.

[0136] Regarding the fixing assembly, there is at least one structure fixed to the skull, preferably a hollow skull pin, which has a fixing and guiding function. The skull pin has a self-tapping thread that can be fastened to the skull. Then, the entire sleeve 100 fixing assembly is attached to the skull pin to maintain a fixed position relative to the patient's skull. The hollow inner hole on the skull pin and the position adjustment structure form a guiding passage for the sleeve 100 to enter and orient.

[0137] Optionally, the external device may include an electroencephalograph, which is used to receive and display biological information of the target biological tissue acquired by the electrode contact 200 .

[0138] The external device may also include a signal generator, which is used to receive the first control signal of the controller, generate an electrical signal according to the first control signal, and transmit the electrical signal to the electrode contact 200; or, it is used to receive biological information of the target biological tissue acquired by the electrode contact 200, and generate an electrical signal according to the biological information of the target biological tissue and transmit it to the electrode contact 200. The electrode contact 200 applies the electrical signal to the target biological tissue to regulate the target biological tissue. The electrical signal may be a stimulation pulse signal or a radio frequency current.

[0139] By applying the embodiments of the present application, at least the following beneficial effects can be achieved: 1. In this embodiment, the cannula 100 is hollow and serves as the probe channel of the interventional instrument. It is a three-section cannula structure, which includes a first rigid section at both ends, a second rigid section and a flexible transition section in the middle. The appropriate flexural modulus is set according to the position and function, so that the cannula as a whole has appropriate flexibility and rigidity during the puncture process, thereby improving the puncture efficiency; the cannula 100 is electrically connected to the electrode connector 600 through the connection contact, and can be manufactured in a detachable mode to improve the flexibility of the structure. The continuous cavity for the interventional instrument to penetrate integrates the internal channel of the cannula 100 and the connection channel of the electrode connector 600, which can compact the structural layout and reduce redundant design. Moreover, the continuous cavity, as the probe channel of the interventional instrument, can enrich the function of the electrode device, and use the cannula 100 and the interventional instrument to work together to bring multiple possible solutions for the ablation of the target biological tissue. Moreover, there is no need to repeatedly implant other electrode probes in the cannula 100, which can reduce the complexity of the operation and thus improve the ablation efficiency.

[0140] 2. At least part of the distal end of the first rigid segment is open, so that when the distal end of the first rigid segment is close to the target biological tissue, the distal end of the interventional instrument can extend beyond the distal end of the first rigid segment and continue to perform short-distance puncture to reach the target biological tissue with a more complex structure, thereby minimizing the damage of the first rigid segment to the target biological tissue.

[0141] 3. Multiple independent channel structures are arranged inside the cannula 100, each of which can allow one or more interventional instruments to pass through, so that the distal end of the interventional instrument reaches the target biological tissue for corresponding ablation and other treatments. The channels of multiple interventional instruments are independent of each other and do not interfere with each other, which can improve the reliability of the interventional instruments.

[0142] 4. Multiple electrode contacts 200 are arranged at circumferential intervals on the outer peripheral wall of the distal end of the first rigid section, and acquire information from each other for analysis and processing to obtain information at the target biological tissue. The outlet of the channel structure is arranged between adjacent electrode contacts 200, staggered with the electrode contacts 200, and does not affect each other.

[0143] The terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, unless otherwise specified, "plurality" means two or more.

[0144] The above is only a partial implementation method of the present application. It should be pointed out that for ordinary technicians in this technical field, without departing from the technical concept of the scheme of the present application, other similar implementation methods based on the technical ideas of the present application are also within the protection scope of the embodiments of the present application.

Claims

1. An electrode structure, characterized in that: include: A sleeve, comprising a first rigid section, a flexible transition section and a second rigid section connected in sequence along an axial direction, wherein the flexural modulus of the first rigid section and the second rigid section is greater than the flexural modulus of the flexible transition section; At least one electrode contact, disposed on the outer peripheral wall and / or the inner peripheral wall at the distal end of the first rigid segment, for obtaining information of the target biological tissue and / or regulating the target biological tissue; at least one first connection contact, disposed on the peripheral wall of the proximal end of the second rigid segment and electrically connected to the electrode contact; an electrode connector, having a connection channel connected to the second rigid section, wherein at least one second connection contact matching the first connection contact is arranged in the connection channel, and the electrode contact is electrically connected to the electrode connector via the first connection contact and the second connection contact; The connecting channel, the first rigid section, the flexible transition section and the second rigid section form a continuous cavity that penetrates the electrode structure. The continuous cavity can be penetrated by interventional instruments and has a guiding and positioning function.

2. The electrode structure according to claim 1, characterized in that: At least one of the first rigid section and the second rigid section is a three-layer structure, comprising a first flexible layer, a hard layer, and a second flexible layer; The first flexible layer is used to contact the interventional instrument, and the second flexible layer is used to contact biological tissue during the puncture process.

3. The electrode structure according to claim 1, characterized in that: The electrode connector is connected to the second rigid section in a non-detachable connection manner or a detachable connection manner.

4. The electrode structure according to claim 1, characterized in that: The first rigid segment has a flexural modulus that is less than the flexural modulus of the second rigid segment.

5. The electrode structure according to claim 1, characterized in that: The distal end of the first rigid section is closed or at least partially open.

6. The electrode structure according to claim 1, characterized in that: The electrode structure further comprises: At least one channel structure, which is open at both ends and hollow, and is disposed inside the sleeve; The inlet of the channel structure is located at the proximal opening of the second rigid segment, the outlet of the channel structure is arranged at at least one of the distal opening and the distal peripheral wall of the first rigid segment, and the outlet of the channel structure is staggered from the position of the electrode contact; The channel structure is capable of allowing interventional instruments to pass through.

7. The electrode structure according to claim 6, characterized in that: The electrode contacts include at least two, which are spaced apart and arranged on the outer peripheral wall of the distal end of the first rigid section; The outlet of the channel structure is arranged between adjacent electrode contacts on the distal peripheral wall of the first rigid section.

8. The electrode structure according to claim 6, characterized in that: The electrode structure further comprises: The sealing component is flexible, and its outer peripheral wall is fixedly connected to the inner peripheral wall at the distal end of the channel structure. It is constructed to deform when the interventional instrument passes through to open the outlet of the channel structure and to seal the outlet of the channel structure without external force.

9. The electrode structure according to claim 1, characterized in that: The electrode structure further comprises at least one of the following: A temperature measuring resistor is arranged on the outer peripheral wall at the far end of the first rigid section; A temperature measuring resistor is arranged on the closed outer end surface of the distal end of the first rigid section; The temperature measuring optical fiber is embedded in the outer peripheral wall of the sleeve and extends along the axial direction of the sleeve. The monitoring end of the temperature measuring optical fiber is fixed to the distal end of the first rigid section.

10. The electrode structure according to claim 9, characterized in that: The temperature measuring resistor is arranged on the outer peripheral wall of the distal end of the first rigid section and is located between adjacent electrode contacts.

11. The electrode structure according to claim 9, characterized in that: The monitoring end of the temperature measuring optical fiber is located between adjacent electrode contacts.

12. An electrode device, characterized in that: Comprising an interventional instrument and an electrode structure as described in any one of claims 1 to 11; The interventional instrument is inserted into the continuous cavity of the electrode structure.

13. The electrode device according to claim 12, characterized in that The interventional instrument comprises at least one of an ablation optical fiber, a temperature measurement optical fiber, an electrode structure, a navigation needle and a core rod.

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