Mouse tail injection vein imaging instrument

Abstract

The invention relates to the technical field of vein development, and discloses a mouse tail injection vein imaging instrument which comprises a supporting box, a base is fixedly installed at the bottom of the left side of the supporting box, a root clamping assembly and a containing assembly are arranged at the top of the supporting box, and a mouse tail supporting table is fixedly installed on the left side of the supporting box; the bottom of the mouse tail supporting table is slidably connected with a developing table, and a screen projection assembly is arranged on the developing table. By screwing the knob, the developing lamp moves from the root of the rat tail to the tail end of the rat tail, and the sliding column slides in the W-shaped groove, so that the rotating table is driven to swing back and forth relative to the fixed table, the rat tail is twisted back and forth, the developing lamp can irradiate the rat tail from multiple angles, and vein development on the rat tail is more accurate and reliable; vein images are collected through the lamp panel, signals are transmitted to the computer, vein image information is processed through the computer, three-dimensional images of the veins are displayed through the display screen, and an operator can conveniently observe the veins on the mouse tail.

Description

Technical Field

[0009] The invention relates to the technical field of vein development, in particular to a mouse tail injection vein imaging device. Background Art

[0010] Acquired immunodeficiency syndrome, also known as AIDS, is caused by infection with the human immunodeficiency virus (HIV). Since the discovery of AIDS, the relevant field has been striving to find a suitable animal model for the study of the pathogenesis, drug treatment and vaccine of AIDS. The establishment of an ideal AIDS animal model is of great significance to the basic research of AIDS.

[0011] Animal models such as mice are widely used in AIDS research. First, they are used to study the pathological mechanism of HIV. Animal models can be used to study the pathogenic mechanism of HIV, including the viral replication process, host immune response, and the interaction between virus and host cells, providing a theoretical basis for the development of new treatment methods.

[0012] The second is drug research and development, which is used to screen and evaluate the efficacy and safety of antiviral drugs, determine the optimal dosage and route of administration of drugs, and provide data support for clinical trials of drugs;

[0013] Third, in vaccine development, HIV-infected animal models can be used to evaluate the protective efficacy of candidate vaccines, determine the optimal dose and vaccination schedule of vaccines, and provide data support for vaccine clinical trials. In short, by injecting healthy human peripheral blood mononuclear cells (PBMC) into NOD / Prkdcscid / IL2rgnull (NPG) mice through the tail vein, a humanized mouse model is established to simulate the HIV infection process, evaluate the efficacy and safety of antiviral drugs, and understand the pathogenesis of the virus, thereby accelerating the development of new drugs and vaccines and providing new strategies and methods for the treatment of AIDS.

[0014] Secondly, the first task after the new drug is developed is to conduct animal experiments. For injectable drugs, they are given to mice through intravenous injection. Traditional injection of the small tail relies on blind injection by experimenters and injection based on experience, so the injection success rate is very low; the mouse tail injection vein imaging device on the market can solve some problems. Just put the mouse tail in the designed triangular tail groove, and place a yellow light source under the tail groove. The blood pressure in the vein has a certain pressure, and the red blood cells have a light absorption effect. When the yellow light is irradiated, the blood vessels will appear as a black strip. The experimenter can easily inject the liquid medicine into the blood vessels. The disadvantage is that the adjustment and fixation of the experimental subjects are not convenient, and the blood vessels cannot be imaged and enlarged, which may cause some troubles to researchers with poor eyesight. Summary of the invention

[0015] 1. Technical issues to be solved

[0016] In view of the shortcomings of the prior art, the present invention provides a mouse tail injection vein imaging device, which has the advantages of good mouse tail fixation effect and good vein development effect, and solves the problems of inconvenient mouse fixation, poor vein development effect, and inconvenience for intravenous injection.

[0017] (II) Technical solution

[0018] In order to achieve the above-mentioned purpose of good fixation effect on mouse tail and good vein development effect, the present invention provides the following technical solutions: a mouse tail injection vein imager, including a support box, a base is fixedly installed on the bottom left side of the support box, a root clamping assembly and a containing assembly are arranged on the top of the support box, a mouse tail support platform is fixedly installed on the left side of the support box, an end clamping assembly is arranged on the left end of the mouse tail support platform, a developing platform is slidably connected to the bottom of the mouse tail support platform, a projection assembly is arranged on the developing platform, and a lubrication assembly is arranged at the bottom of the developing platform.

[0019] Preferably, the root clamping assembly includes a motor fixedly mounted on the front side of the top of the support box, a drive shaft is fixedly mounted on the left output end of the motor, and a pressure rod is fixedly mounted on the left end of the drive shaft; two supports are fixedly mounted on the top of the support box, the drive shaft is rotatably connected to the two supports, a pad is fixedly mounted on the top of the left side of the support box, a V-shaped groove is opened in the middle of the pad, and the pressure rod cooperates with the pad to clamp the rat tail.

[0020] Preferably, the containing assembly includes a bracket, two plug plates are plugged into the bracket, a containing tube is fixedly installed between the two plug plates, ten through grooves are penetrated on the left half of the containing tube, a tail groove is penetrated on the plug plate located on the left side of the containing tube, a mouse groove is penetrated on the plug plate located on the right side of the containing tube, a linear groove is penetrated on the top of the containing tube, and the linear groove penetrates the plug plate on the right side; a conical cover is slidably connected inside the containing tube, a bolt is threadedly connected to the top of the conical cover, and the bolt is slidably connected to the linear groove.

[0021] Preferably, the bracket includes a bracket body, two slots are provided on the top of the bracket body, the bracket body is hinged on the top of the support box, two support arms are hinged on the bottom of the bracket body, the right ends of the two support arms pass through a connecting shaft for rotation connection, two frame plates are fixedly installed on the top of the support box, the connecting shaft passes through and is slidably connected to the frame plate, a sliding plate is fixedly installed on the front end of the connecting shaft, the sliding plate is slidably connected to the driving shaft, a threaded hole is provided on the lower half of the sliding plate, and a rotating rod is rotatably connected between the two supports; a thread is provided on the right half of the rotating rod, and the sliding plate is threadedly connected to the rotating rod through the threaded hole, a gear 1 is fixedly installed on the circumferential surface of the right end of the driving shaft, and a gear 2 is fixedly installed on the right end of the rotating rod, and the gear 1 is meshed with the gear 2.

[0022] Preferably, the rat tail support platform includes a fixed platform and a rotating platform, the fixed platform is fixedly installed on the left side of the support box, a semicircular slide rail is fixedly installed on the left end of the fixed platform, a semicircular slide groove is opened at the right end of the rotating platform, the cross-section of the semicircular slide rail is "convex" shaped, and the rotating platform is slidably connected to the semicircular slide rail through the semicircular slide groove; a V-shaped groove 2 is opened on the top of the fixed platform, a V-shaped groove 3 is opened on the top of the rotating platform, and an arc-shaped flange 1 is fixedly installed on the circumferential surface of the left end of the rotating platform; an avoidance groove is opened through the bottom of the fixed platform, and the avoidance groove extends to the bottom wall of the V-shaped groove 2, and a light-transmitting plate is fixedly installed on the fixed platform at the connection point between the V-shaped groove 2 and the avoidance groove; a sliding column is fixedly installed at the center of the bottom of the rotating platform.

[0023] Preferably, the end clamping assembly includes an adjusting shaft, a convex strip one is fixedly installed on the circumferential surface of the right end of the adjusting shaft, a spiral groove is provided on the circumferential surface of the adjusting shaft, the spiral groove is located on the left side of the convex strip one, a sliding ring is sleeved on the right end of the adjusting shaft, an embedding groove is provided on the inner wall of the sliding ring, the sliding ring is slidably connected to the convex strip one through the embedding groove, and a clamping plate is fixedly installed on the outer wall of the sliding ring; a connecting cylinder is fixedly installed on the left end of the sliding ring, an internal threaded ring is rotatably connected to the left end of the connecting cylinder, the internal threaded ring is threadedly connected to the spiral groove, and a convex strip two is fixedly installed on the outer wall of the internal threaded ring; a mounting groove one is provided on the left end of the rotating table, a mounting groove two is provided on the right end surface of the rotating table located at the mounting groove one, a guide groove is provided on the inner wall of the left half of the rotating table located at the mounting groove two, and a connecting window is provided on the top of the rotating table, and the connecting window is connected with the right half of the mounting groove two; the clamping plate passes through the connecting window, the convex strip two is slidably connected in the guide groove, and the adjusting shaft is rotatably connected to the adjusting shaft and the mounting groove two.

[0024] Preferably, two guide rails are fixedly installed on the top of the base, and two sliding sleeves are fixedly installed on the bottom of the developing table, and the sliding sleeves are slidably connected to the guide rails. A semi-cylindrical groove is provided on the top of the developing table, and the arc-shaped flange one fits on the semi-cylindrical groove. A developing lamp is arranged at the center of the right end of the semi-cylindrical groove, and a W-shaped groove is provided on the developing table, and the W-shaped groove is wavy, and the sliding column is slidably connected in the W-shaped groove; a rack plate is fixedly installed on the front side of the developing table, and a vertical plate is fixedly installed on the top of the base, and a knob is rotatably connected to the vertical plate, and a gear three is fixedly installed on the rear end of the knob, and the gear three is meshed with the rack plate; an arc-shaped flange two is fixedly installed on the right end surface of the semi-cylindrical groove, and the arc-shaped flange two fits on the bottom of the fixed table.

[0025] Preferably, the projection assembly includes two columns fixedly mounted on the top of the right end of the developing table, light boards are fixedly mounted on the top of the two columns, a camera is arranged at the bottom of the light board, a display screen is hinged on the front side of the right end of the developing table, and the light board is connected to the display screen signal.

[0026] Preferably, the lubrication assembly comprises a lubricating oil tank fixedly mounted on the top of the base, a baffle is fixedly mounted at the center of the right inner wall of the lubricating oil tank, a piston plate is slidably connected in the lubricating oil tank, two sliding tubes are fixedly mounted on the right side of the piston plate, the sliding tubes penetrate and slide and are connected to the right end of the lubricating oil tank, the right ends of the two sliding tubes are connected to a fixed groove, the fixed groove is fixedly mounted on the bottom of the developing table, and a liquid guide hole is penetrated in an array at the left end of the sliding tube; the left end of the lubricating oil tank is connected to a hose, the other end of the hose is fixedly mounted on the left end of the developing table, an oil injection channel is opened inside the developing table, the left end of the oil injection channel is connected to the hose, the right end of the oil injection channel is located at the top of the right end of the developing table, an oil shield is fixedly mounted on the top of the right end of the developing table, and the oil shield blocks the upper side of the right end of the oil injection channel; a temporary storage groove is opened in the left half of the developing table, a reflux groove is opened at the top of the left end of the developing table, the reflux groove is connected to the temporary storage groove, a reflux channel is opened inside the developing table, one end of the reflux channel is connected to the temporary storage groove, and the other end is connected to the fixed groove.

[0027] (III) Beneficial effects

[0028] Compared with the prior art, the present invention provides a mouse tail injection vein imaging device having the following features:

[0029] Beneficial effects:

[0030] 1. The mouse tail injection vein imaging device drives the driving shaft to rotate through a motor, drives the pressure rod to deflect, so that the pressure rod and the pad are clamped at the root of the mouse tail to fix the root of the mouse tail; by screwing the adjustment shaft, the sliding ring is driven to rotate, and the clamping plate is deflected into the V-shaped groove three, and at the same time, the internal thread ring pulls the sliding ring to the left through the connecting tube, so that the clamping plate is deflected into the V-shaped groove three while moving to the left; the clamping plate is pressed tightly on the end of the mouse tail and pushed to the left to tighten the mouse tail; thereby achieving the purpose of fixing the two ends of the mouse tail, tightening the mouse tail, and facilitating the visualization of the mouse tail vein;

[0031] 2. In the mouse tail injection vein imaging device, during the rotation of the driving shaft, the gear 1 rotates with the driving shaft, and cooperates with the meshing action of the gear 1 and the gear 2 to drive the rotating rod to rotate; then, through the threaded connection between the sliding plate and the rotating rod, the sliding plate and the connecting shaft are driven to move leftward; thereby driving the right end of the support arm to move leftward, causing the bracket body to deflect relative to the support box, so that the bracket body is lower on the left and higher on the right, promoting the blood flow to the tail of the mouse; thereby achieving the purpose of further promoting the imaging effect of the mouse tail vein;

[0032] 3. The mouse tail injection vein imaging device drives gear 3 to rotate by turning the knob, thereby driving the rack plate and the developing table to move leftward along the guide rail, and the developing lamp moves in the avoidance groove, so that the developing lamp moves from the root of the mouse tail to the end of the mouse tail to develop the veins on the mouse tail; in the process of the developing table moving to the left, the sliding column slides in the W-shaped groove, thereby driving the rotating table to swing back and forth relative to the fixed table. Since the root and the end of the mouse tail are fixed, the mouse tail is twisted back and forth, so that the developing lamp can irradiate the mouse tail from multiple angles, making the vein development on the mouse tail more accurate and reliable;

[0033] 4. The mouse tail injection vein imager collects vein images through the light board and transmits the signal to the computer, which processes the vein image information and displays the three-dimensional image of the vein through the display screen. The image displayed on the display screen can be enlarged or reduced by touching the display screen, which is convenient for the operator to observe the veins on the mouse tail. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 This is a schematic diagram of the three-dimensional structure of a mouse tail injection vein imaging device proposed by the present invention;

[0035] Figure 2 This is a schematic diagram of the three-dimensional structure of a containing component and a root clamping component of a mouse tail injection vein imaging device proposed by the present invention;

[0036] Figure 3 It is a schematic diagram of a three-dimensional exploded structure of a containing component and a root clamping component of a mouse tail injection vein imaging device proposed by the present invention;

[0037] Figure 4 This is a schematic diagram of a three-dimensional exploded structure of a containing component of a mouse tail injection vein imaging device proposed by the present invention;

[0038] Figure 5 This is a schematic diagram of the three-dimensional structure of a mouse tail support platform of a mouse tail injection vein imaging device proposed by the present invention;

[0039] Figure 6 This is a schematic diagram of the upward-looking structure of a rotating platform of a mouse tail injection vein imaging device proposed by the present invention;

[0040] Figure 7 This is a schematic diagram of the three-dimensional structure of a rotating table and an end clamping assembly of a mouse tail injection vein imaging device proposed by the present invention;

[0041] Figure 8 This is a schematic diagram of the three-dimensional structure of the end clamping assembly of a mouse tail injection vein imaging device proposed by the present invention;

[0042] Fig. 9 This is a schematic diagram of the three-dimensional structure of a mouse tail support platform, a developing platform and a projection screen assembly of a mouse tail injection vein imaging device proposed by the present invention;

[0043] Fig.10 This is a schematic diagram of the three-dimensional structure of a mouse tail injection vein imaging device proposed by the present invention, in which the developing platform and the mouse tail supporting platform are separated;

[0044] Fig.11 This is a schematic diagram of the main cross-sectional structure of a developing table and a lubricating component of a mouse tail injection vein imaging device proposed by the present invention;

[0045] Fig.12 The present invention provides a schematic diagram of the three-dimensional cross-section structure of the lubricating oil tank of a mouse tail injection vein imaging device.

[0046] In the figure: 100, support box; 200, base; 300, root clamping assembly; 400, holding assembly; 500, rat tail support table; 600, end clamping assembly; 700, developing table; 800, projection assembly; 900, lubrication assembly;

[0047] 201, guide rail; 301, motor; 302, drive shaft; 303, pressure rod; 304, support; 305, pad; 306, V-shaped groove 1; 401, plug plate; 402, receiving tube; 403, through groove; 404, linear groove; 405, conical cover; 406, bolt; 407, bracket body; 408, slot; 409, support arm; 410, connecting shaft; 411, frame plate; 412, sliding plate; 413, threaded hole; 414, rotating rod; 415, gear 1; 416, gear 2;

[0048] 501, fixed platform; 502, rotating platform; 503, semicircular slide rail; 504, semicircular slide groove; 505, V-shaped groove 2; 506, V-shaped groove 3; 507, arc flange 1; 508, avoidance groove; 509, light-transmitting plate; 510, sliding column;

[0049] 601, adjusting shaft; 602, convex strip 1; 603, spiral groove; 604, sliding ring; 605, embedded groove; 606, clamping plate; 607, connecting tube; 608, internal thread ring; 609, convex strip 2; 610, mounting groove 1; 611, mounting groove 2; 612, guide groove; 613, connecting window;

[0050] 701, sleeve; 702, semi-cylindrical groove; 703, developing lamp; 704, W-shaped groove; 705, rack plate; 706, vertical plate; 707, knob; 708, gear three; 709, arc flange two; 801, column; 802, lamp board; 803, display screen; 901, lubricating oil tank; 902, baffle; 903, piston plate; 904, sliding tube; 905, fixing groove; 906, liquid guide hole; 907, hose; 908, oil filling channel; 909, oil shield; 910, temporary storage tank; 911, reflux tank; 912, reflux channel. DETAILED DESCRIPTION

[0051] In the description of the present application, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0052] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0053] See also Figure 1A mouse tail injection vein imaging device includes a support box 100, a base 200 is fixedly installed on the bottom left side of the support box 100, a root clamping component 300 and a containing component 400 are arranged on the top of the support box 100, a mouse tail support platform 500 is fixedly installed on the left side of the support box 100, an end clamping component 600 is arranged at the left end of the mouse tail support platform 500, a developing platform 700 is slidably connected to the bottom of the mouse tail support platform 500, a projection component 800 is arranged on the developing platform 700, and a lubrication component 900 is arranged at the bottom of the developing platform 700.

[0054] See also Figure 2 , the root clamping assembly 300 includes a motor 301 fixedly mounted on the front side of the top of the support box 100, a driving shaft 302 is fixedly mounted on the left output end of the motor 301, and a pressure rod 303 is fixedly mounted on the left end of the driving shaft 302; two supports 304 are fixedly mounted on the top of the support box 100, and the driving shaft 302 is connected to the two supports 304 through rotation, and the driving shaft 302 is supported by the supports 304. A pad 305 is fixedly mounted on the top of the left side of the support box 100, and a V-shaped groove 306 is opened in the middle of the pad 305, and the pressure rod 303 cooperates with the pad 305 to clamp the mouse tail. After the mouse is stored by the holding assembly 400, the mouse tail is placed in the V-shaped groove 306, and then the driving shaft 302 is driven to rotate by the motor 301, which drives the pressure rod 303 to deflect, so that the pressure rod 303 and the pad 305 are clamped at the root of the mouse tail to fix the mouse tail.

[0055] See also Figure 2-Figure 4 The containing assembly 400 includes a bracket, on which two plug-in plates 401 are plugged, a receiving tube 402 is fixedly installed between the two plug-in plates 401, ten through grooves 403 are penetrated on the left half of the receiving tube 402, a through groove is penetrated on the plug-in plate 401 located on the left side of the receiving tube 402, a mouse groove is penetrated on the plug-in plate 401 located on the right side of the receiving tube 402, a linear groove 404 is penetrated on the top of the receiving tube 402, and the linear groove 404 penetrates the plug-in plate 401 on the right side; a conical cover 405 is slidably connected inside the receiving tube 402, a bolt 406 is threadedly connected to the top of the conical cover 405, and the bolt 406 is slidably connected to the linear groove 404. Place the mouse into the accommodating tube 402 from the mouse placing slot, with the mouse's head facing the right and the mouse's tail passing through the tail slot; then insert the conical cover 405 from the mouse placing slot into the accommodating tube 402, and put the conical cover 405 on the mouse's head. Finally, tighten the bolt 406 so that the bolt 406 fits on the top of the accommodating tube 402, and position the conical cover 405, thereby completing the storage of the mouse.

[0056] See also Figure 2-Figure 4The bracket includes a bracket body 407, and two slots 408 are provided on the top of the bracket body 407 for plugging two plug boards 401. The bracket body 407 is hinged on the top of the support box 100, and two support arms 409 are hinged on the bottom of the bracket body 407. The right ends of the two support arms 409 are connected with a connecting shaft 410 through rotation. Two frame-shaped plates 411 are fixedly installed on the top of the support box 100, and the connecting shaft 410 is connected with the frame-shaped plate 411 through sliding. The connecting shaft 410 slides in the frame-shaped plate 411, thereby driving the rear end of the support arm 409 to move along the left and right directions, driving the bracket body 407 to deflect relative to the support box 100. When the bracket body 407 is deflected to a state of left low and right high, when the accommodating tube 402 and the plug board 401 are placed on the top of the bracket body 407, the head of the mouse is high and the tail is low, which promotes the blood flow of the mouse to the tail and enhances the development effect of the mouse tail.

[0057] A sliding plate 412 is fixedly installed at the front end of the connecting shaft 410, and the sliding plate 412 is slidably connected to the driving shaft 302. A threaded hole 413 is provided at the lower half of the sliding plate 412, and a rotating rod 414 is rotatably connected between the two supports 304; a thread is provided on the right half of the rotating rod 414, and the sliding plate 412 is threadedly connected to the rotating rod 414 through the threaded hole 413. A gear 1 415 is fixedly installed on the circumferential surface of the right end of the driving shaft 302, and a gear 2 416 is fixedly installed at the right end of the rotating rod 414, and gear 1 415 is meshed with gear 2 416. When the motor 301 drives the driving shaft 302 to rotate and causes the pressure rod 303 to deflect and clamp the mouse tail, the gear 1 415 rotates together with the driving shaft 302, and the meshing action of the gear 1 415 and the gear 2 416 drives the rotating rod 414 to rotate; and then the sliding plate 412 and the connecting shaft 410 are driven to move to the left through the threaded connection between the sliding plate 412 and the rotating rod 414.

[0058] See also Figure 5-Figure 6 The rat tail support platform 500 includes a fixed platform 501 and a rotating platform 502. The fixed platform 501 is fixedly installed on the left side of the support box 100. A semicircular slide rail 503 is fixedly installed on the left end of the fixed platform 501. A semicircular slide groove 504 is opened on the right end of the rotating platform 502. The cross section of the semicircular slide rail 503 is in a "convex" shape. The rotating platform 502 is slidably connected to the semicircular slide rail 503 through the semicircular slide groove 504 to prevent the rotating platform 502 from detaching from the fixed platform 501.

[0059] A V-shaped groove 2 505 is provided on the top of the fixed platform 501, and a V-shaped groove 3 506 is provided on the top of the rotating platform 502. The rat tail is placed inside the V-shaped groove 2 505 and the V-shaped groove 3 506. An arc-shaped flange 1 507 is fixedly installed on the circumferential surface of the left end of the rotating platform 502. An avoidance groove 508 is provided through the bottom of the fixed platform 501, and the avoidance groove 508 penetrates the bottom wall of the V-shaped groove 2 505. A light-transmitting plate 509 is fixedly installed on the fixed platform 501 at the connection between the V-shaped groove 2 505 and the avoidance groove 508. The light-transmitting plate 509 can be made of glass, transparent acrylic or other materials, and is used to transmit light. A sliding column 510 is fixedly installed at the center of the bottom of the rotating platform 502.

[0060] See also Figure 7-Figure 8 The end clamping assembly 600 includes an adjusting shaft 601, a mounting groove 1 610 is opened at the left end of the rotating table 502, a mounting groove 2 611 is opened on the right end surface of the rotating table 502 located at the mounting groove 1 610, the adjusting shaft 601 is arranged along the axis of the mounting groove 1 610 and the mounting groove 2 611, and the adjusting shaft 601 is rotatably connected in the mounting groove 1 610.

[0061] A convex strip 1 602 is fixedly mounted on the circumferential surface of the right end of the adjusting shaft 601, and a spiral groove 603 is provided on the circumferential surface of the adjusting shaft 601, and the number of turns of the spiral groove 603 is half a turn. The spiral groove 603 is located on the left side of the convex strip 1 602. A sliding ring 604 is sleeved on the right end of the adjusting shaft 601, and the outer diameter of the sliding ring 604 is equal to the inner diameter of the mounting groove 2 611. An embedded groove 605 is provided on the inner wall of the sliding ring 604, and the sliding ring 604 is slidably connected to the convex strip 1 602 through the embedded groove 605, so that when the adjusting shaft 601 and the convex strip 1 602 rotate, the sliding ring 604 is driven to rotate synchronously, and in this process, the sliding ring 604 can slide relative to the convex strip 1 602.

[0062] A clamping plate 606 is fixedly installed on the outer wall of the sliding ring 604, and a connecting window 613 is opened on the top of the rotating platform 502, and the connecting window 613 is connected to the right half of the second installation groove 611; the clamping plate 606 passes through the connecting window 613. Therefore, when the sliding ring 604 rotates, the clamping plate 606 is driven to deflect and squeeze and fix the end of the rat tail. A connecting tube 607 is fixedly installed on the left end of the sliding ring 604, and an internal thread ring 608 is rotatably connected to the left end of the connecting tube 607. The internal thread ring 608 is threadedly connected to the spiral groove 603, and a convex strip 609 is fixedly installed on the outer wall of the internal thread ring 608; a guide groove 612 is opened on the inner wall of the left half of the second installation groove 611 of the rotating platform 502, and the convex strip 609 is slidably connected in the guide groove 612. Therefore, when the adjusting shaft 601 rotates, the internal thread ring 608 and the second protruding strip 609 slide along the guide groove 612 , and through the connecting action of the connecting tube 607 , the sliding ring 604 is driven to move along the guide groove 612 .

[0063] Therefore, when the end of the rat tail is fixed, the adjusting shaft 601 is screwed to drive the sliding ring 604 to rotate, and the clamping plate 606 deflects into the V-shaped groove 3506. At the same time, the internal thread ring 608 pulls the sliding ring 604 to the left through the connecting tube 607, so that the clamping plate 606 deflects into the V-shaped groove 3506 and moves to the left. The clamping plate 606 is pressed against the end of the rat tail and pushed to the left, so that the rat tail is tightened.

[0064] See also Figure 9-10 Two guide rails 201 are fixedly installed on the top of the base 200, and two sliding sleeves 701 are fixedly installed on the bottom of the developing table 700. The sliding sleeves 701 are slidably connected to the guide rails 201.

[0065] A semi-cylindrical groove 702 is provided on the top of the developing table 700, and the arc-shaped flange 1 507 is attached to the semi-cylindrical groove 702. An arc-shaped flange 2 709 is fixedly installed on the right end surface of the semi-cylindrical groove 702, and the arc-shaped flange 2 709 is attached to the bottom of the fixed table 501. A gap is reserved between the fixed table 501 and the rotating table 502 and the semi-cylindrical groove 702, and the two ends of the gap are sealed by the arc-shaped flange 1 507 and the arc-shaped flange 2 709.

[0066] A developing lamp 703 is disposed at the center of the right end of the semi-cylindrical groove 702, and the developing lamp 703 moves inside the avoidance groove 508. A W-shaped groove 704 is provided on the developing table 700 located on the semi-cylindrical groove 702, and the W-shaped groove 704 is wavy, and the slide post 510 is slidably connected in the W-shaped groove 704. Therefore, when the developing table 700 moves along the guide rail 201, the slide post 510 slides in the W-shaped groove 704, so that the rotating table 502 deflects relative to the fixed table 501.

[0067] A rack plate 705 is fixedly installed on the front side of the developing table 700, and a vertical plate 706 is fixedly installed on the top of the base 200. A knob 707 is rotatably connected to the vertical plate 706, and a gear 3 708 is fixedly installed on the rear end of the knob 707. The gear 3 708 is meshed with the rack plate 705. By turning the knob 707, the gear 3 708 is driven to rotate, thereby driving the rack plate 705 and the developing table 700 to move along the guide rail 201.

[0068] See also Fig. 9The projection assembly 800 includes two columns 801 fixedly mounted on the top of the right end of the developing table 700, a light board 802 is fixedly mounted on the top of the two columns 801, a camera is arranged at the bottom of the light board 802, a display screen 803 is hingedly connected to the front side of the right end of the developing table 700, and the light board 802 is connected to the display screen 803 by signal. The light board 802 and the display screen 803 are both connected to the computer by signal. The developing lamp 703 is used to illuminate the mouse tail so that the veins on the mouse tail appear. The vein image is then collected by the light board 802, and the signal is transmitted to the computer. The vein image information is processed by the computer, and the three-dimensional image of the vein is displayed on the display screen 803. The image displayed on the display screen 803 can be enlarged or reduced by touching the display screen 803.

[0069] See also Figure 11-Figure 12 The lubrication assembly 900 includes a lubricating oil tank 901 fixedly mounted on the top of the base 200, a piston plate 903 is slidably connected in the lubricating oil tank 901, two sliding tubes 904 are fixedly mounted on the right side of the piston plate 903, the sliding tubes 904 penetrate and slide and connect to the right end of the lubricating oil tank 901, the right ends of the two sliding tubes 904 are connected with a fixed groove 905, and the fixed groove 905 is fixedly mounted on the bottom of the developing table 700, so that when the developing table 700 moves along the guide rail 201, the fixed groove 905, the sliding tube 904 and the piston plate 903 are driven to move synchronously. A liquid guide hole 906 is opened through the array at the left end of the sliding tube 904; a baffle 902 is fixedly mounted at the center of the inner wall on the right side of the lubricating oil tank 901, and the piston plate 903 is blocked by the baffle 902. When the piston plate 903 is attached to the surface of the baffle 902, the liquid guide hole 906 is inside the lubricating oil tank 901.

[0070] The left end of the lubricating oil tank 901 is connected to a hose 907, and the other end of the hose 907 is fixedly installed on the left end of the developing table 700. An oil injection channel 908 is provided inside the developing table 700, and the left end of the oil injection channel 908 is connected to the hose 907. The right end of the oil injection channel 908 is located at the top of the right end of the developing table 700. An oil shield 909 is fixedly installed on the top of the right end of the developing table 700, and the oil shield 909 blocks the upper side of the right end of the oil injection channel 908. When the piston plate 903 slides to the left inside the lubricating oil tank 901, the piston plate 903 squeezes the lubricating oil in the left half of the lubricating oil tank 901, so that the lubricating oil passes through the hose 907 and the oil injection channel 908, and is injected into the gap between the fixed table 501 and the rotating table 502 and the semi-cylindrical groove 702, and the lubricating oil enters the inside of the W-shaped groove 704, reducing the friction between the sliding column 510 and the W-shaped groove 704.

[0071] A temporary storage groove 910 is provided in the left half of the developing table 700, a reflux groove 911 is provided at the top of the left end of the developing table 700, and the reflux groove 911 is connected to the temporary storage groove 910. A reflux channel 912 is provided inside the developing table 700, and one end of the reflux channel 912 is connected to the temporary storage groove 910, and the other end is connected to the fixed groove 905. When the piston plate 903 slides to the left inside the lubricating oil tank 901, the right half of the lubricating oil tank 901 is in a negative pressure state, so that the lubricating oil in the gap between the fixed table 501 and the rotating table 502 and the semi-cylindrical groove 702 is sucked into the right half of the lubricating oil tank 901 through the reflux groove 911, the temporary storage groove 910, the reflux channel 912, the fixed groove 905, the sliding pipe 904 and the liquid guide hole 906. When the developing table 700 slides to the left to expose the reflux groove 911 , the lubricating oil can be added to the temporary storage groove 910 through the reflux groove 911 .

[0072] When in use, a mouse is placed into the accommodation tube 402 from the mouse placement slot, with the mouse head facing the right, and the mouse tail passing through the tail insertion slot; the conical cover 405 is then inserted from the mouse placement slot into the accommodation tube 402, and the conical cover 405 is sleeved on the mouse head; finally, the bolt 406 is screwed, so that the bolt 406 fits on the top of the accommodation tube 402, and the conical cover 405 is positioned, so that the mouse is stably stored in the accommodation tube 402;

[0073] Then, the two insert plates 401 are correspondingly inserted into the slots 408, and the rat tail is placed at the V-shaped groove 306. After that, the motor 301 drives the drive shaft 302 to rotate, driving the pressure rod 303 to deflect, so that the pressure rod 303 and the pad 305 are clamped at the root of the rat tail to fix the root of the rat tail;

[0074] During the rotation of the driving shaft 302, the gear 1 415 rotates together with the driving shaft 302, and the meshing action of the gear 1 415 and the gear 2 416 drives the rotating rod 414 to rotate; then, through the threaded connection between the sliding plate 412 and the rotating rod 414, the sliding plate 412 and the connecting shaft 410 are driven to move to the left; thereby driving the right end of the support arm 409 to move to the left, causing the bracket body 407 to deflect relative to the support box 100, so that the bracket body 407 is lower on the left and higher on the right, thereby promoting the blood flow to the tail of the mouse;

[0075] By screwing the adjusting shaft 601, the sliding ring 604 is driven to rotate, and the clamping plate 606 is deflected into the V-shaped groove 3 506. At the same time, the internal thread ring 608 pulls the sliding ring 604 to the left through the connecting tube 607, so that the clamping plate 606 is deflected into the V-shaped groove 3 506 and moves to the left; the clamping plate 606 is pressed against the end of the rat tail and pushed to the left to tighten the rat tail;

[0076] By turning the knob 707, the gear 3 708 is driven to rotate, thereby driving the rack plate 705 and the developing table 700 to move leftward along the guide rail 201, and the developing lamp 703 moves in the avoidance groove 508, so that the developing lamp 703 moves from the root of the rat tail to the end of the rat tail to develop the vein on the rat tail;

[0077] When the developing table 700 moves to the left, the slide column 510 slides in the W-shaped groove 704, thereby driving the rotating table 502 to swing back and forth relative to the fixed table 501. Since the root and the end of the rat tail are fixed, the rat tail is twisted back and forth, so that the developing lamp 703 can illuminate the rat tail from multiple angles, making the vein development on the rat tail more accurate and reliable.

[0078] Then, the light board 802 collects the vein image and transmits the signal to the computer, which processes the vein image information and displays the three-dimensional image of the vein on the display screen 803. The image displayed on the display screen 803 can be enlarged or reduced by touching the display screen 803, so that the operator can observe the veins on the mouse tail;

[0079] When the developing table 700 moves to the left, the piston plate 903 squeezes the lubricating oil in the left half of the lubricating oil tank 901, so that the lubricating oil passes through the hose 907 and the oil filling channel 908 and is injected into the gap between the fixed table 501 and the rotating table 502 and the semi-cylindrical groove 702, and the lubricating oil enters the W-shaped groove 704 to reduce the friction between the sliding column 510 and the W-shaped groove 704; the right half of the lubricating oil tank 901 is in a negative pressure state, so that the lubricating oil in the gap between the fixed table 501 and the rotating table 502 and the semi-cylindrical groove 702 is sucked into the right half of the lubricating oil tank 901 through the reflux groove 911, the temporary storage groove 910, the reflux channel 912, the fixed groove 905, the sliding tube 904 and the liquid guide hole 906.

[0080] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A mouse tail injection vein imaging device, comprising a support box (100), characterized in that: A base (200) is fixedly installed at the bottom of the left side of the support box (100), a root clamping assembly (300) and a containing assembly (400) are arranged on the top of the support box (100), a rat tail support platform (500) is fixedly installed on the left side of the support box (100), an end clamping assembly (600) is arranged at the left end of the rat tail support platform (500), a developing platform (700) is slidably connected to the bottom of the rat tail support platform (500), a projection assembly (800) is arranged on the developing platform (700), and a lubrication assembly (900) is arranged at the bottom of the developing platform (700).

2. The mouse tail injection vein imaging device according to claim 1, characterized in that: The root clamping assembly (300) comprises a motor (301) fixedly mounted on the front side of the top of the support box (100), a drive shaft (302) fixedly mounted on the left output end of the motor (301), and a pressure rod (303) fixedly mounted on the left end of the drive shaft (302); Two supports (304) are fixedly installed on the top of the support box (100), and the driving shaft (302) is rotatably connected to the two supports (304). A pad (305) is fixedly installed on the top of the left side of the support box (100), and a V-shaped groove (306) is opened in the middle of the pad (305). The pressure rod (303) cooperates with the pad (305) to clamp the rat tail.

3. The mouse tail injection vein imaging device according to claim 2, characterized in that: The containing assembly (400) comprises a bracket, two plugging plates (401) are plugged into the bracket, a receiving tube (402) is fixedly installed between the two plugging plates (401), ten through grooves (403) are penetrated on the left half of the receiving tube (402), a through groove is penetrated on the plugging plate (401) located on the left side of the receiving tube (402), a mouse groove is penetrated on the plugging plate (401) located on the right side of the receiving tube (402), a straight groove (404) is penetrated on the top of the receiving tube (402), and the straight groove (404) penetrates the plugging plate (401) on the right side; A conical cover (405) is slidably connected inside the containing tube (402), a bolt (406) is threadedly connected to the top of the conical cover (405), and the bolt (406) is slidably connected to the linear groove (404).

4. The mouse tail injection vein imaging device according to claim 3, characterized in that: The bracket comprises a bracket body (407), the top of the bracket body (407) is provided with two slots (408), the bracket body (407) is hinged to the top of the support box (100), the bottom of the bracket body (407) is hinged with two support arms (409), the right ends of the two support arms (409) are penetrated with a connecting shaft (410) for rotational connection, two frame plates (411) are fixedly installed on the top of the support box (100), the connecting shaft (410) is penetrated and slidably connected to the frame plate (411), a sliding plate (412) is fixedly installed at the front end of the connecting shaft (410), the sliding plate (412) is slidably connected to the driving shaft (302), a threaded hole (413) is provided on the lower half of the sliding plate (412), and a rotating rod (414) is rotatably connected between the two supports (304); The right half of the rotating rod (414) is provided with a thread, the sliding plate (412) is threadedly connected to the rotating rod (414) through a threaded hole (413), a gear 1 (415) is fixedly installed on the circumferential surface of the right end of the driving shaft (302), and a gear 2 (416) is fixedly installed on the right end of the rotating rod (414), and the gear 1 (415) is meshed with the gear 2 (416).

5. The mouse tail injection vein imaging device according to claim 1, characterized in that: The rat-tail support platform (500) comprises a fixed platform (501) and a rotating platform (502); the fixed platform (501) is fixedly mounted on the left side of the support box (100); a semicircular slide rail (503) is fixedly mounted on the left end of the fixed platform (501); a semicircular slide groove (504) is provided on the right end of the rotating platform (502); the cross section of the semicircular slide rail (503) is in a "convex" shape; the rotating platform (502) is slidably connected to the semicircular slide rail (503) via the semicircular slide groove (504); The top of the fixed platform (501) is provided with a second V-shaped groove (505), the top of the rotating platform (502) is provided with a third V-shaped groove (506), and an arc-shaped flange (507) is fixedly installed on the circumferential surface of the left end of the rotating platform (502); The bottom of the fixed platform (501) is provided with an avoidance groove (508), the avoidance groove (508) extends to the bottom wall of the second V-shaped groove (505), and a light-transmitting plate (509) is fixedly installed on the fixed platform (501) at the connection point between the second V-shaped groove (505) and the avoidance groove (508); A sliding column (510) is fixedly installed at the center of the bottom of the rotating platform (502).

6. The mouse tail injection vein imaging device according to claim 5, characterized in that: The end clamping assembly (600) comprises an adjusting shaft (601), a convex strip (602) is fixedly mounted on the circumferential surface of the right end of the adjusting shaft (601), a spiral groove (603) is provided on the circumferential surface of the adjusting shaft (601), and the spiral groove (603) is located on the left side of the convex strip (602), a sliding ring (604) is sleeved on the right end of the adjusting shaft (601), an embedding groove (605) is provided on the inner wall of the sliding ring (604), the sliding ring (604) is slidably connected to the convex strip (602) through the embedding groove (605), and a clamping plate (606) is fixedly mounted on the outer wall of the sliding ring (604); A connecting tube (607) is fixedly mounted on the left end of the sliding ring (604), and an internal thread ring (608) is rotatably connected to the left end of the connecting tube (607). The internal thread ring (608) is threadedly connected to the spiral groove (603), and a second convex strip (609) is fixedly mounted on the outer wall of the internal thread ring (608); The left end of the rotating platform (502) is provided with a first mounting groove (610), the right end surface of the rotating platform (502) located at the first mounting groove (610) is provided with a second mounting groove (611), the inner wall of the left half of the rotating platform (502) located at the second mounting groove (611) is provided with a guide groove (612), and the top of the rotating platform (502) is provided with a connecting window (613), and the connecting window (613) is connected with the right half of the second mounting groove (611); The clamping plate (606) passes through the connecting window (613), the second protruding strip (609) is slidably connected in the guide groove (612), and the adjusting shaft (601) is rotatably connected in the adjusting shaft (601) and the second mounting groove (611).

7. The mouse tail injection vein imaging device according to claim 5, characterized in that: Two guide rails (201) are fixedly installed on the top of the base (200), and two sliding sleeves (701) are fixedly installed on the bottom of the developing table (700), and the sliding sleeves (701) are slidably connected to the guide rails (201). A semi-cylindrical groove (702) is opened on the top of the developing table (700), and the arc-shaped flange (507) is attached to the semi-cylindrical groove (702). A developing lamp (703) is arranged at the center of the right end of the semi-cylindrical groove (702). The developing table (700) is located on the semi-cylindrical groove (702) and is opened with a W-shaped groove (704), and the W-shaped groove (704) is wavy, and the sliding column (510) is slidably connected in the W-shaped groove (704); A rack plate (705) is fixedly mounted on the front side of the developing table (700), a vertical plate (706) is fixedly mounted on the top of the base (200), a knob (707) is rotatably connected to the vertical plate (706), a gear three (708) is fixedly mounted on the rear end of the knob (707), and the gear three (708) is meshed with the rack plate (705); A second arc-shaped flange (709) is fixedly mounted on the right end surface of the semi-cylindrical groove (702), and the second arc-shaped flange (709) is fitted on the bottom of the fixing platform (501).

8. The mouse tail injection vein imaging device according to claim 1, characterized in that: The projection assembly (800) comprises two columns (801) fixedly mounted on the top of the right end of the developing table (700), a light board (802) fixedly mounted on the top of the two columns (801), a camera being arranged at the bottom of the light board (802), a display screen (803) being hingedly connected to the front side of the right end of the developing table (700), and the light board (802) being signal-connected to the display screen (803).

9. The mouse tail injection vein imaging device according to claim 1, characterized in that: The lubrication assembly (900) comprises a lubrication oil tank (901) fixedly mounted on the top of the base (200), a baffle (902) fixedly mounted at the center of the right inner wall of the lubrication oil tank (901), a piston plate (903) slidably connected inside the lubrication oil tank (901), two sliding tubes (904) fixedly mounted on the right side of the piston plate (903), the sliding tubes (904) penetrate and slide connected to the right end of the lubrication oil tank (901), the right ends of the two sliding tubes (904) are connected with fixed grooves (905), the fixed grooves (905) are fixedly mounted on the bottom of the developing table (700), and the left end of the sliding tube (904) is penetrated by an array of liquid guide holes (906); The left end of the lubricating oil tank (901) is connected to a hose (907), the other end of the hose (907) is fixedly mounted on the left end of the developing table (700), an oil injection channel (908) is provided inside the developing table (700), the left end of the oil injection channel (908) is connected to the hose (907), the right end of the oil injection channel (908) is located at the top of the right end of the developing table (700), an oil shield (909) is fixedly mounted on the top of the right end of the developing table (700), and the oil shield (909) blocks the upper side of the right end of the oil injection channel (908); A temporary storage groove (910) is provided in the left half of the developing table (700), a reflux groove (911) is provided at the top of the left end of the developing table (700), the reflux groove (911) is connected with the temporary storage groove (910), a reflux channel (912) is provided inside the developing table (700), one end of the reflux channel (912) is connected with the temporary storage groove (910), and the other end is connected with the fixed groove (905).

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