Face composition containing hydrolyzed opuntia ficus-indica flower extract

Hydrolyzed pear fruit cactus flower extract was prepared by biological enzyme-supercritical fluid extraction method, and combined with silver ion solution at a ratio of 1:10, solving the problem that traditional acne removal products are highly irritating and difficult to effectively target acne, achieving a more comprehensive targeting of the pathogenesis of acne and improving skin health effects.

CN120093652APending Publication Date: 2025-06-06OPAL COSMETICS HUIZHOU
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Patent Information

Application Number
CN202510322824.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-19
Publication Date
2025-06-06

AI Technical Summary

Technical Problem

Traditional acne removal products may have high irritation, which can easily cause adverse reactions such as skin allergies, redness and swelling, and it is difficult to effectively target the pathogenesis of acne.

Method used

Hydrolyzed pear fruit cactus flower extract was prepared by biological enzyme-supercritical fluid extraction method, and combined it with silver ion solution in a ratio of 1:10 to prepare facial composition.

Benefits of technology

By combining the moisturizing, anti-inflammatory, antioxidant effects of hydrolyzed pear fruit cactus flower extract with the antibacterial properties of silver ions, synergistically targeting the pathogenesis of acne more comprehensively, helping to repair damaged skin and improving skin health status in the long term.

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Abstract

The invention relates to the technical field of skin care products. Specifically disclosed is a facial composition containing a hydrolyzed opuntia ficus-indica flower extract. Comprising the following raw materials in percentage by weight: 0.05%-15% of a hydrolyzed opuntia ficus-indica flower extract, 0.1%-20.0% of a humectant, 0.5%-3.0% of grease, 0.8%-4% of an emulsifier, 0.1%-2% of a thickening agent, 0.1%-8% of a functional additive, 0.03%-1.5% of a preservative, 0.01%-1.5% of a pH regulator and the balance of pure water. The functional additive is ceramide NP and a silver ion solution. According to the composition, the adding amount of the silver ions is matched with that of the composition according to the ratio of 1: 10, stimulation of the silver ions is neutralized, stimulation of microorganisms and metabolites to skin tissue is reduced, accordingly, inflammatory response is relieved, repair of damaged skin is facilitated, and the health state of the skin is improved for a long time.
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Description

Technical Field

[0001] The invention belongs to the technical field of skin care products, and in particular relates to a facial composition containing a hydrolyzed opuntia cactus flower extract. Background Art

[0002] Fast-paced life, irregular work and rest schedules, environmental pollution and other factors have led to an increasing number of people with acne. Whether it is adolescents in puberty or adults facing work and life pressure, they are all prone to acne problems, which has led to an increasing market demand for acne-removing products. Consumers have higher and higher requirements for appearance, and their attention and importance to skin problems such as acne are constantly increasing. They are more willing to invest time and money to find effective acne-removing products and solutions.

[0003] Traditional acne-removing products may have the problem of being highly irritating and easily cause adverse reactions such as skin allergies, redness and swelling. Consumers are increasingly inclined to choose mild and natural acne-removing products to reduce irritation and burden on the skin. As a natural plant extract, hydrolyzed prickly pear cactus flower extract has relatively mild characteristics, which meets consumers' pursuit of natural ingredients. In recent years, plant extracts have been increasingly widely used in the field of skin care products and have been recognized and loved by consumers. Many consumers believe that plant extracts have better safety and effectiveness, and their improvement effect on the skin is more gentle and lasting. Hydrolyzed prickly pear cactus flower extract has gradually attracted attention in the acne-removing product market due to its unique efficacy.

[0004] Opuntia ficus-indica (L.) Mill. is a fleshy shrub or small tree of the genus Opuntia in the family Cactaceae. It is commonly known as "Xiantao" in western Sichuan. The plant is 1.5 to 5 meters tall. The branches and leaves are light green or gray-green, broadly oval, obovate oval to oblong, with a flat surface and many small nests. When it blooms, the flowers are bright orange-red. When the fruit is ripe, it is shaped like a pear, so it is called Opuntia ficus-indica. The flowering period is from May to June. Opuntia ficus-indica is native to Mexico and distributed in warm areas of the world. After being introduced to greenhouse cultivation, the thorns will degenerate into bristle-like or missing. Like plants of the same genus, Opuntia ficus-indica prefers strong light and is heat-resistant, drought-resistant and barren-resistant. Opuntia ficus-indica also has great medicinal value, edible value, economic value and ornamental value. According to the World Plant Medicine, the prickly pear cactus has a long history of being used as medicine and food in Mexico. The flowers, fruits and stems are usually used as medicine. The flowers have antibacterial, astringent, hemostatic and antidiarrheal effects, and can be used to treat gastrointestinal diseases. The fruits contain mucus, sugars, vitamin C and some fruit acids, and are mostly used to make jams and alcoholic beverages. The stems have antibacterial, anti-inflammatory and moisturizing effects. The plants can be used to raise cochineal insects to produce natural magenta pigments. They are tenacious and easy to manage, making them very suitable for landscape flower arrangements.

[0005] Opuntia cactus flower contains a variety of active ingredients:

[0006] 1. Polysaccharides. The polysaccharides in the hydrolyzed Opuntia cactus flower extract have multiple physiological activities. In terms of skin moisturizing, they can form a moisturizing film on the skin surface, bind water molecules through hydrogen bonds, prevent skin moisture loss, and maintain the skin's hydration. In addition, polysaccharides also have antioxidant capacity, which can remove free radicals in the skin, reduce the damage of free radicals to skin cells, and prevent the oxidative stress response caused by acne inflammation to a certain extent.

[0007] 2. Flavonoids: Flavonoids are one of the important components of the extract. They have significant antioxidant and anti-inflammatory properties. Antioxidant effects can inhibit lipid peroxidation and protect the integrity of skin cell membranes. In terms of anti-inflammatory effects, they can effectively inhibit the release of inflammatory factors and reduce inflammatory symptoms such as skin redness, swelling, and itching, which has potential value for relieving acne inflammation.

[0008] 3. Amino acids and minerals. The amino acids in the extract are components of the skin's natural moisturizing factor, which helps to enhance the skin's moisturizing ability and participate in the metabolism of skin cells. Minerals such as magnesium, calcium, and potassium play an important role in maintaining the normal physiological functions of skin cells, such as regulating the osmotic pressure inside and outside the cells, participating in the activation of enzymes, etc., providing protection for skin health.

[0009] Many different extraction methods have been studied, including single microwave extraction, solvent extraction, enzyme extraction, ultrasonic extraction, etc. It was found that each method has its own advantages and disadvantages, and the extraction process and efficiency are not ideal. Summary of the invention

[0010] The technical problem to be solved by the present invention is to provide a facial composition containing a hydrolyzed Opuntia pyri flower extract. The flower of Opuntia pyri is used as a raw material, and the hydrolyzed Opuntia pyri flower extract is prepared by a bioenzyme-supercritical fluid extraction method to ensure the activity of the effective ingredients and give full play to the maximum characteristics of the moisturizing, anti-inflammatory and antioxidant effects of the Opuntia pyri flower. Through long-term experiments, it is found that the best effect can be achieved by adding a silver ion solution and an extract in a ratio of 1:10. A single silver ion may cause irritation and toxicity to the skin in terms of dosage, but when combined with a mild plant extract, it not only neutralizes the stimulation of silver ions, but the anti-inflammatory and antioxidant effects of the extract can reduce inflammation and oxidative damage, and silver ions can directly inhibit the growth of Propionibacterium acnes. The synergistic effect of the two may more comprehensively target the pathogenesis of acne, help repair damaged skin, and improve the health of the skin in the long term.

[0011] The technical solution adopted by the present invention to solve the above problems is as follows:

[0012] A facial composition containing hydrolyzed opuntia cactus flower extract comprises the following components calculated by weight percentage:

[0013] 0.05% to 15% hydrolyzed prickly pear cactus flower extract; 0.1% to 20.0% moisturizer; 0.5% to 3.0% oil; 0.8% to 4% emulsifier; 0.1% to 2% thickener; 0.1% to 8% functional additive; 0.03% to 1.5% preservative; 0.01% to 1.5% pH adjuster, and the balance is pure water.

[0014] Further, the moisturizing agent includes at least one of natural moisturizing factor, glycerol, 1,3-butylene glycol, panthenol, betaine, and sodium hyaluronate. Further, the natural moisturizing factor includes at least one of sodium lactate, sodium DL-pyrrolidone carboxylate, and allantoin. The chemical name of glycerol is propylene glycol. The glycerol molecule contains three -OH groups that form hydrogen bonds with water molecules, absorbs moisture from the air or deep layers of the skin, plays a good role in hygroscopic moisturizing, and has a significant moisturizing effect on human skin and hair, and can increase the solubility of other components in cosmetics. Glycerol is widely used in various cosmetics to replenish moisture to the stratum corneum of the skin, enhance the skin's moisturizing ability, maintain the water-oil balance of the skin, facilitate acne recovery, regulate the physiological effects of the skin, maintain skin health, and improve the sense of use. Low concentrations of glycerol are gentle to the skin. Panthenol, also known as vitamin B5, helps to enhance the moisturizing effect and promote the functional repair of damaged skin barriers. Sodium lactate is the sodium salt of lactic acid, a natural moisturizing factor with unique pH adjustment and moisturizing functions, and a non-sticky feel. Sodium lactate can prevent the evaporation of skin moisture, keep the skin moisturized, and thus prevent the formation of wrinkles. Urea exists in the stratum corneum of the skin and is the main component of the skin's natural moisturizing factor NMF.

[0015] Preferably, the moisturizing agent is glycerin, 1,3-butylene glycol and sodium lactate of natural origin, which are used in a mass ratio of 3:1.5:0.5.

[0016] Furthermore, the oil includes at least one of dimethicone, dimethiconol, palmitoyl palmitate, camellia oleifera seed oil, cetyl ethylhexanoate, isooctyl palmitate, rose seed oil, avocado butter, and cocoa seed butter. Palmitoyl palmitate is rich in omega-9, carotenoids, natural tocopherol, squalene and other ingredients, has excellent antioxidant properties, reduces solar erythema, and helps repair the skin barrier.

[0017] Preferably, the oil is palmyra palm fruit oil or camellia sinensis seed oil.

[0018] Furthermore, the emulsifier includes at least one of glyceryl stearate, polysorbate-60, cetearyl alcohol, cetearyl glucoside, steareth-2, and steareth-21.

[0019] Preferably, the emulsifier is cetearyl alcohol and cetearyl glucoside. Cetearyl alcohol and cetearyl glucoside can emulsify, stabilize, thicken, moisturize, and are mild and low irritation.

[0020] Furthermore, the thickener includes at least one of carbomer polymer, hydroxyethyl cellulose, xanthan gum, ammonium acryloyldimethyltaurate / VP copolymer, hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer, polyacrylamide / C13-14 isoparaffin / lauryl polyoxyethylene ether, and sodium polyacrylate.

[0021] Preferably, the thickener is xanthan gum and ammonium acryloyldimethyltaurate / VP copolymer. The thickener can stabilize the system under high temperature and is not easy to turn yellow.

[0022] Furthermore, the efficacy additives include ceramide NP and silver ion solution. The silver ion solution refers to silver purified by electrolysis, reacted with nitric acid to generate silver nitrate, and the silver nitrate is then processed by molecular sieve technology to obtain silver nitrate.

[0023] Furthermore, the preparation method of the hydrolyzed Opuntia cactus flower extract comprises the following steps:

[0024] A. Grinding: Wash and dry the flowers of Opuntia pyrifolia, and then ultrafine grind them to obtain Opuntia pyrifolia pollen;

[0025] B. Enzyme hydrolysis: according to the weight of the prickly pear cactus pollen, soak it by adding an extraction solvent, add the composite biological enzyme into it, stir it evenly, heat it to start enzymolysis, and obtain an enzymolysis solution;

[0026] C. Inactivation: After obtaining the enzymatic solution, rapidly raise the temperature to inactivate the composite biological enzyme;

[0027] D. Supercritical extraction: The cooled enzymatic hydrolyzate and the extraction solvent are subjected to a first supercritical extraction in an extraction tank of a supercritical fluid extractor to obtain a first extract and a residue; the first extract and the residue are subjected to a second supercritical extraction to obtain a second extract;

[0028] E. Drying: The first and second extracts are uniformly mixed, filtered to remove residue, concentrated and vacuum dried to obtain the hydrolyzed prickly pear cactus flower extract.

[0029] Furthermore, the mesh size of the Opuntia pomegranate pollen is 60 to 80 meshes.

[0030] Furthermore, the mass ratio of the Opuntia pomegranate pollen to the extraction solvent is 1:10.

[0031] Furthermore, the extraction solvent is at least one of water, methanol, ethanol, propylene glycol, and 1-3 butanediol.

[0032] Preferably, the extraction solvent is water and ethanol in a volume ratio of 7:3.

[0033] Furthermore, the pH value of the enzymatic hydrolysis is 4.0-6.0, the enzymatic hydrolysis temperature is 40-60° C., and the enzymatic hydrolysis time is 1-4 hours.

[0034] Furthermore, the inactivation includes rapidly heating the enzymatic hydrolysate to 100°C for rapid inactivation, and cooling the temperature to 30°C to 45°C after inactivation for 1 minute.

[0035] Furthermore, the composite biological enzyme is prepared by cellulase, amylase and pectinase in a mass ratio of 0.8-1:1-1.3:0.8-1, and is added in an amount of 0.5%-5% of the weight of the prickly pear cactus pollen after adding the extraction solvent.

[0036] Furthermore, in the supercritical fluid extraction method, the first extraction time is 25 to 45 minutes, the extraction pressure is 3 to 8 MPa; the second extraction time is 25 to 45 minutes, the extraction pressure is 3 to 8 MPa; and the extraction temperature is 40 to 60°C.

[0037] Furthermore, the fluid substance used in the supercritical fluid extraction is at least one of carbon dioxide, nitrous oxide, ethylene, chloroform, nitrogen and chlorine.

[0038] Preferably, the fluid substance used in the supercritical extraction is carbon dioxide.

[0039] The present invention has the following beneficial effects:

[0040] The present invention uses the flower of the prickly pear cactus as a raw material, and adopts a biological enzyme-supercritical fluid extraction method to prepare a hydrolyzed prickly pear cactus flower extract, thereby ensuring the activity of the effective ingredients and giving full play to the maximum characteristics of the hydrolyzed prickly pear cactus flower extract in terms of moisturizing, anti-inflammatory and antioxidant effects. The present invention has found through long-term experiments that the best effect can be achieved by combining the addition amount of the silver ion solution and the hydrolyzed prickly pear cactus flower extract in a ratio of 1:10. The anti-inflammatory and antioxidant properties of the hydrolyzed prickly pear cactus flower extract are combined with the antibacterial properties of the silver ions. The anti-inflammatory and antioxidant effects of the extract can reduce inflammation and oxidative damage, and the silver ions can directly inhibit the growth of Propionibacterium acnes. The synergistic effect of the two may more comprehensively target the pathogenesis of acne, help repair damaged skin, and improve the health of the skin in the long term. DETAILED DESCRIPTION

[0041] The present invention is described in detail below with reference to the examples, which are only preferred embodiments of the present invention and are not intended to limit the present invention. The methods involved in the present invention are commonly used methods in the art unless otherwise specified; the reagents involved can be obtained from common commercial channels unless otherwise specified.

[0042] Specifically, preparing a hydrolyzed opuntia cactus flower extract comprises the following steps:

[0043] A. Wash and dry the flowers of Opuntia cactus, grind them into 60-80 mesh, and set aside;

[0044] B. feeding the prickly pear cactus pollen pretreated in step A into a reactor through a quantitative feeder, adding 10 times of solvent (30% ethanol, 70% pure water) according to the weight of the prickly pear cactus pollen for soaking, and adding 0.5% to 5% composite biological enzyme (cellulase, amylase, pectinase prepared in a mass ratio of 0.8 to 1: 1 to 1.3: 0.8 to 1) into the reactor, stirring evenly, heating to 40 to 60° C., maintaining enzymolysis for 1 to 4 hours, and obtaining an enzymolysis solution;

[0045] C. After the enzymatic hydrolysis in step B, the enzymatic hydrolyzate is rapidly heated to 100°C for rapid inactivation, and then cooled to 30°C to 45°C after 1 minute of inactivation;

[0046] D. The enzymatic hydrolyzate after cooling in step C is fed into the extraction tank from the feed port of the supercritical extractor, and the extraction solvent is heated and fed into the extraction tank from the slag discharge end of the supercritical extractor;

[0047] E. extracting the enzymatic hydrolyzate and the extraction solvent in an extraction tank of a supercritical fluid extractor under normal pressure for the first time, with an extraction time of 30 to 40 minutes and an extraction pressure of 3 to 8 MPa to obtain a first extract and a residue;

[0048] F. subjecting the residue from the first extraction to a second supercritical extraction, the extraction time is 30 to 40 minutes, the extraction pressure is 3 to 8 MPa, and a second extract is obtained; the first and second extracts from step E and step F are uniformly mixed, filtered to remove the residue, concentrated and vacuum dried to obtain a hydrolyzed prickly pear cactus flower extract.

[0049] According to the above-mentioned preparation method of hydrolyzed Opuntia cactus flower extract, Examples 1 to 8 and Comparative Examples 1 to 2 are designed to compare and illustrate the preferred extraction process conditions.

[0050] Table 1: Process conditions for preparation of hydrolyzed Opuntia cactus flower extract

[0051]

[0052] It can be seen from the results in Table 1 that if only enzymatic hydrolysis or supercritical extraction is used, high extraction efficiency cannot be obtained, but the combination of the two can significantly improve the efficiency. According to the analysis of Example 3 in Table 1, the optimal enzymatic hydrolysis temperature of the extraction method is 45°C, 2.5% of the composite biological enzyme is added, the pH value is adjusted to 5.3, the enzymatic hydrolysis time is 2h, the optimal extraction temperature is 40°C, and the extraction time is 40min. Under the optimal conditions, the extraction rate of the supercritical fluid extraction method and the enzymatic hydrolysis method is 25.6%. Compared with the single supercritical fluid extraction method (14.33%), it has increased by 11.27%; compared with the single enzymatic hydrolysis method (13.89%), it has increased by 11.71%.

[0053] The present invention adds the hydrolyzed prickly pear cactus flower extract obtained in Example 3 in Table 1 to the facial composition to obtain the facial composition configuration examples 1 to 4 and comparative examples 1 to 2 in Table 2 below. The configuration method is a conventional configuration and mixing technology, which will not be described in detail here. The specific formula is shown in Table 2 below:

[0054] Table 2: Facial composition configuration

[0055]

[0056]

[0057]

[0058] The efficacy of the above 6 facial compositions was evaluated by two methods: instrumental efficacy evaluation and human sensory evaluation. The test methods are as follows:

[0059] (I) Short-term test:

[0060] 60 volunteers aged 15 to 30 years with mild to moderate acne were selected and randomly divided into two groups, 30 in each group. The experimental group used a facial composition containing silver ion solution and hydrolyzed prickly pear cactus flower extract, and the control group used a facial composition without silver ion solution and hydrolyzed prickly pear cactus flower extract, which was applied to the acne area on the face after cleansing in the morning and evening every day for 2 weeks. The acne conditions of the volunteers were evaluated before the start of the experiment, in the first week, and in the second week, including the number of acne, degree of inflammation, and skin oil content.

[0061] (1) Acne quantity assessment method:

[0062] Clinical direct counting method: Under natural light or specific light source, directly observe the acne-prone areas on the face and count different types of acne lesions such as comedones, papules, pustules, nodules, cysts, etc.

[0063] Mild acne usually has less than 30 spots; moderate acne has 31 to 50 spots; and severe acne has more than 50 spots.

[0064] (2) Methods for assessing the degree of inflammation:

[0065] Comprehensive judgment based on observation of skin color and subjective feelings: The data on the degree of inflammation is accurate to one decimal place. The data is obtained by observing the external manifestations such as the degree of redness and swelling of the skin, and combining the patient's description of subjective feelings such as pain, and then comprehensively evaluating and scoring.

[0066] The inflammation scoring standard was 0 to 3 points, with 0 for no inflammation and 3 for severe inflammation.

[0067] (3) Skin oil content:

[0068] The skin oil meter measures the oil content on the skin surface by contacting the sensor with the skin surface, and can obtain specific oil value.

[0069] Table 3: Comparison of short-term test results

[0070]

[0071]

[0072] (II) Long-term testing:

[0073] Ten volunteers aged 18 to 30 years with mild to moderate acne were selected and randomly divided into two groups, 5 in each group. The experimental group used a facial composition containing a silver ion solution and hydrolyzed prickly pear cactus flower extract in a ratio of 0.5:15, and the control group used a facial composition containing a silver ion solution and hydrolyzed prickly pear cactus flower extract in a ratio of 1:10, and applied it to the acne area on the face after cleansing the face in the morning and evening every day. Volunteers were selected from the short-term test and the test lasted for 3 months and 6 months.

[0074] Table 4: Comparison of long-term test results

[0075]

[0076] The inflammation scoring standard (0-3 points, 0 points for no inflammation, 3 points for severe inflammation) was used.

[0077] By comparing and analyzing the experimental data of the number of acne, the degree of inflammation and the skin oil content in the short-term test in Table 3 and the long-term test in Table 4, the facial composition of the hydrolyzed pear cactus flower extract compounded with silver ion solution and the optimal ratio of 1:10 showed significant effect in removing acne. In terms of reducing the number of acne, the gap with the control group and the short-term experimental test increased over time, proving that it has an inhibitory effect on the growth of acne. In terms of improving the degree of inflammation, it can effectively reduce the inflammation score and reduce the inflammatory reactions such as redness and swelling caused by acne. For the skin oil content, the facial composition can regulate oil secretion and create a skin environment that is not conducive to the growth of acne. The comparison of experimental data fully shows that the facial composition of the hydrolyzed pear cactus flower extract compounded with silver ions at a ratio of 1:10 has obvious advantages in the acne removal effect compared with the facial composition without silver ion solution and the facial composition at a ratio of 0.5:15. Long-term experiments can effectively reduce the number of acne, reduce the degree of inflammation and regulate the skin oil content.

[0078] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.

[0079] In addition, various embodiments of the present invention may be arbitrarily combined, and as long as they do not violate the concept of the present invention, they should also be regarded as the contents disclosed by the present invention.

Claims

1. A facial composition containing hydrolyzed Opuntia pyrifolia flower extract, characterized in that: Contains the following components calculated by weight percentage: The composition comprises 0.05% to 15% hydrolyzed prickly pear cactus flower extract, 0.1% to 20.0% moisturizing agent, 0.5% to 3.0% oil, 0.8% to 4% emulsifier, 0.1% to 2% thickener, 0.1% to 8% functional additive, 0.01% to 1.5% pH regulator and the balance of pure water.

2. The facial composition containing hydrolyzed Opuntia pyrifolia flower extract according to claim 1, characterized in that: The moisturizing agent includes at least one of natural moisturizing factor, glycerin, 1,3-butylene glycol, panthenol, betaine, and sodium hyaluronate. Furthermore, the natural moisturizing factor includes at least one of sodium lactate, sodium DL-pyrrolidonecarboxylate, and allantoin.

3. The facial composition containing hydrolyzed Opuntia pyrifolia flower extract according to claim 1, characterized in that: The oil comprises at least one of polydimethylsiloxane, polydimethylsiloxane alcohol, palmitoyl palmitate, isopropyl palmitate, camellia sinensis seed oil, cetyl ethylhexanoate, isooctyl palmitate, rose seed oil, avocado butter and cocoa seed butter.

4. The facial composition containing hydrolyzed Opuntia pyrifolia flower extract according to claim 1, characterized in that: The emulsifier includes at least one of glyceryl stearate, polysorbate-60, cetearyl alcohol, cetearyl glucoside, steareth-2, and steareth-21.

5. The facial composition containing hydrolyzed Opuntia pyrifolia flower extract according to claim 1, characterized in that: The thickener comprises at least one of carbomer polymer, hydroxyethyl cellulose, xanthan gum, ammonium acryloyldimethyltaurate / VP copolymer, hydroxyethyl acrylate / sodium acryloyldimethyltaurate copolymer, polyacrylamide / C13-14 isoparaffin / lauryl polyoxyethylene ether, and sodium polyacrylate.

6. The facial composition containing hydrolyzed Opuntia pyrifolia flower extract according to claim 1, characterized in that: The efficacy additives include silver ion solution and ceramide NP.

7. The facial composition containing hydrolyzed Opuntia pyrifolia flower extract according to claim 1, characterized in that: The preparation method of the hydrolyzed Opuntia cactus flower extract comprises the following steps: A. Grinding: Wash and dry the flowers of Opuntia pyrifolia, and then ultrafine grind them to obtain Opuntia pyrifolia pollen; B. Enzyme hydrolysis: according to the weight of the prickly pear cactus pollen, soak it by adding an extraction solvent, add the composite biological enzyme into it, stir it evenly, heat it to start enzymolysis, and obtain an enzymolysis solution; C. Inactivation: After obtaining the enzymatic solution, rapidly raise the temperature to inactivate the biological enzyme; D. Supercritical extraction: The cooled enzymatic hydrolyzate and the extraction solvent are subjected to a first supercritical extraction in an extraction tank of a supercritical fluid extractor to obtain a first extract and a residue; the first extract and the residue are subjected to a second supercritical extraction to obtain a second extract; E. Drying: The first and second extracts are uniformly mixed, filtered to remove residue, concentrated and vacuum dried to obtain the hydrolyzed prickly pear cactus flower extract.

8. The method for preparing the hydrolyzed Opuntia cactus flower extract according to claim 7, characterized in that: The composite biological enzyme is prepared from cellulase, amylase and pectinase in a mass ratio of 0.8-1:1-1.3:0.8-1, and is added in an amount of 0.5%-5% of the weight of the prickly pear cactus pollen after adding the extraction solvent.

9. The method for preparing the hydrolyzed Opuntia cactus flower extract according to claim 7, characterized in that: The pH of the enzymatic hydrolysis is 4.0 to 6.0, the enzymatic hydrolysis temperature is 40 to 60° C., and the enzymatic hydrolysis time is 1 to 4 hours.

10. The method for preparing the hydrolyzed Opuntia cactus flower extract according to claim 7, characterized in that: The first extraction time of supercritical extraction is 25 to 45 minutes, and the extraction pressure is 3 to 8 MPa; the second extraction time is 25 to 45 minutes, and the extraction pressure is 3 to 8 MPa; the extraction temperature is 40 to 60°C.

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