Brain-like training memory gel and information storage and encryption application thereof

Abstract

The invention discloses brain-like training memory gel and information storage and encryption application thereof.The corresponding preparation method comprises the steps that S1, a temperature-sensitive monomer, a functional material and an initiator are prepared into an aqueous solution, the aqueous solution is placed in an ice-water bath environment for standing, a cross-linking agent is N, N '-methylene bisacrylamide, and the initiator is ammonium persulfate; and S2, adding a reducing agent N, N, N ', N'-tetramethylethylenediamine into the aqueous solution in the step S1. S3, stirring the solution obtained in S2, transferring the solution to a preset container, and performing standing reaction for preset time in a gas environment and a temperature environment with a preset oxygen content ratio to obtain memory gel; s4, performing heat transfer printing patterning on the brain-like training memory gel, and then cooling to enable the pattern to disappear; and short-time development of the heat transfer printing pattern is realized when heating is carried out again. According to the invention, multi-mode information coding, storage and encryption can be realized. The method can be widely applied to the field of functional polymer materials.

Description

Technical Field

[0001] The present invention relates to the field of functional polymer materials, and in particular to a brain-like trainable memory gel and information storage and encryption applications thereof. Background Art

[0002] Memories are generated by interconnected networks of neurons in the brain (also called memory engrams). Depending on the frequency and depth of personal experience, the brain can be trained to varying degrees, thereby possessing multimodal information management capabilities such as short-term memory, long-term memory, practice makes perfect, and forgetting. Under this mechanism, after receiving information, the brain will first process and filter a large amount of information to form short-term memory, while information that has been trained multiple times or has a profound impact on itself will be stored by the brain to form long-term memory, which can be easily accessed at any time. The clever coordination of different memory behaviors makes the brain's information input-storage-output processing efficiency far superior to existing computers. At a more microscopic level, the process involves the self-folding of proteins and the transmission of specific information with another protein. The difficulties and challenges faced in forming efficient online stimulation are unimaginable.

[0003] Similar to the process of information processing in the brain or computer, intelligent stimulus-responsive polymers can respond (signal output) when stimulated by the external environment (signal input). Due to their excellent flexibility and biocompatibility, they show great application prospects in the fields of brain-computer interface, biological detection, and drug sustained release. However, traditional stimulus-responsive materials are relatively single binary states, and the response behavior of the material will disappear with the removal of the stimulus, making it difficult to complete brain-like efficient information screening and storage. Although researchers can initially obtain some step-by-step enhanced or adaptive stimulus-responsive polymer materials through methods such as crystal phase adjustment and secondary polymerization, the development of specific stimulus-responsive materials is still in its early stages and often focuses on the study of its own mechanical properties, which is far from achieving the same information management capabilities and functions as the brain. Therefore, the development of new brain-like trainable memory polymer materials with multiple response modes is the key to achieving efficient brain-like information screening, storage and management, and is expected to have an important impact in the fields of information storage and encryption applications. Summary of the invention

[0004] In view of this, in order to solve the technical problems of the single response behavior of existing intelligent response materials and the low security of information storage and encryption, in the first aspect, the present invention proposes a method for preparing a brain-like trainable memory gel, the method comprising the following steps:

[0005] S1. Prepare an aqueous solution of a thermosensitive monomer, a functional material, an initiator, and a crosslinking agent, and place the solution in an ice water bath for standby use. The crosslinking agent is N,N'-methylenebisacrylamide, and the initiator is ammonium persulfate;

[0006] S2, adding a reducing agent N,N,N',N'-tetramethylethylenediamine to the aqueous solution of S1, wherein the oxidant in S1 and the reducing agent in S2 constitute a redox free radical initiation system;

[0007] S3. After stirring the solution obtained in S2 evenly again, quickly transfer it to a flat glass container, and let it stand in a gas environment with a certain oxygen content ratio and temperature environment for a preset reaction time to obtain a hydrogel sheet.

[0008] In some embodiments, step S1 may include:

[0009] The temperature-sensitive monomer may be isopropyl acrylamide (NIPAM), N,N-dimethylaminoethyl methacrylate (DMAEMA), vinyl caprolactam (VCL), 2-acrylamide-caprolactam (ACL), etc., or a mixture of multiple temperature-sensitive monomers or temperature-sensitive monomers and non-temperature-sensitive monomers. The mass fraction of the monomer and water is 3.0% to 70%, and the content of the crosslinking agent is 0 to 8% of the molar ratio of the mixed monomer.

[0010] The functional materials include polydopamine (PDA), fluorescent molecule 8-aniline-1-naphthalenesulfonic acid, photothermal material gold nanorods, etc. They can be selectively added or not added when preparing the memory gel.

[0011] In some embodiments, step S2 may include:

[0012] The content of the initiator is 0-8% of the molar content of the mixed monomers, and the molar ratio of the reducing agent to the oxidizing agent does not exceed 1.0.

[0013] The free radical initiation system in step S2 is not limited to the redox free radical initiation system, and the initiators involved include ammonium persulfate, potassium persulfate, azobisisobutyronitrile, benzoyl peroxide, hydrogen peroxide, etc.

[0014] In some embodiments, step S3 may include:

[0015] After the reducing agent is added, it is still necessary to stir again for 1 to 5 minutes before transferring it to the glass vessel. It is further preferred that the glass vessel is a conventional glass culture dish. Before preparing the gel sheet, the volume of the aqueous solution and the amount of monomers need to be calculated in advance to ensure that the sheet thickness meets the requirements.

[0016] The oxygen content range set in step S3 is 0% to 100%, and the temperature setting range is 0 to 25°C.

[0017] In a second aspect, the present invention further provides a brain-like trainable memory gel prepared by the above-mentioned preparation method.

[0018] In a third aspect, the present invention further proposes a method for information storage and encryption application, which is implemented based on the brain-like trainable memory gel as described above, and comprises the following steps:

[0019] The brain-like trainable memory gel is subjected to thermal transfer patterning, and then cooled to make the pattern disappear, and when heated again, the thermal transfer pattern is developed in a short time.

[0020] Among them, the thermal transfer method can be completed by infrared mask exposure writing, laser writing and thermal stamp transfer;

[0021] The cooling method can be carried out by natural cooling or active cooling;

[0022] The method of heating again is a hot water bath method.

[0023] In a fourth aspect, the present invention further proposes another method for information storage and encryption application, which is implemented based on the above-mentioned brain-like trainable memory gel and includes the following steps:

[0024] The memory gel containing the photothermal material can be patterned by laser printing using a laser reading and writing system, and can also be used to encode, store, encrypt and read data points.

[0025] The laser reading and writing system comprises a writing laser, a reading laser, a laser sensor, a three-axis platform, a motor control driver, a music synthesis module and a program control unit (VLSI).

[0026] The writing laser, reading laser and MTH hydrogel are fixed on a three-axis platform. The single-chip microcomputer sends a pulse width modulation (PWM) signal to the motor control driver to realize the movement of the three-axis platform. At the same time, the writing laser is also controlled by the single-chip microcomputer to meet the power and time requirements of laser writing. The information written into the gel is collected by the reading laser and encoded by an analog-to-digital converter (ADC). The encoded binary or multi-bit information is then transmitted back to (VLSI), which decrypts the data through a universal asynchronous receiver / transmitter (USART) and controls the music synthesis module to play the information in the data. The information encryption key is a program-controlled reading laser path, a program-controlled threshold definition function, or a combination of the two; the stored music information is only for illustration, and the protection object of the present invention is not limited to a specific encoding method.

[0027] The information written into the gel will be stored inside the gel for a long time. The gel volume can be thinned or reduced in proportion by dehydration. The quality of the dehydrated gel will decrease, and the hydrated gel can be restored to its original appearance. The information written into the gel will be stored inside the gel for a long time. After 370 days or even longer, the information decay rate of the sealed gel is less than 3%.

[0028] On the other hand, the present invention also provides a calibration method for a laser reading and writing system, wherein the writing laser and the reading laser are fixed on a laser engraving machine that can move synchronously, and a series of dots are punched on a flat substrate using the writing laser, and the Z value of each dot moves downward by x, and after the writing is completed, it returns to the starting point Z1, and the reading laser is used to start reading the above value, and when it is found that the nth laser writing point is the focus of the writing laser, the focal length Z2 of the reading laser is found at this point. Then the focal position of the writing laser when writing information in the memory gel can be determined by the focal length Zr+L of the reading laser. Here, L is a constant (Z1-Z2+xn).

[0029] Based on the above scheme, the present invention provides a brain-like trainable memory gel and its information storage and encryption application, and its beneficial effects specifically include:

[0030] 1) The thermosensitive memory trainable hydrogel prepared by the present invention has a simple synthesis method and has multiple modes such as short-term memory, long-term memory, proficiency improvement and forgetting, enriching the intrinsic properties of stimulus-responsive materials.

[0031] 2) Functional materials of different properties can be added to the thermosensitive memory trainable hydrogel prepared by the present invention to enable physical quantities such as light, heat, electricity, and force to be converted and managed into signals according to the memory mode of the memory gel.

[0032] 3) The temperature-sensitive memory trainable hydrogel prepared by the present invention can be patterned in a variety of ways, and the patterned information can be developed and self-erased in a short time, that is, the short-term memory information storage security is higher.

[0033] 4) The laser reading and writing system developed by the present invention based on the temperature-sensitive memory trainable hydrogel realizes laser printing and reading, and data storage, encoding, encryption and reading can be realized by using the difference in transmittance and reflectivity of the phase change region. The reading path and the reading parameter threshold judgment logic can be used as keys respectively, which significantly enhances the security and wide applicability of encrypted information.

[0034] 5) The thermosensitive memory trainable hydrogel prepared by the present invention can absorb / dehydrate water on demand. This property can be used to achieve higher resolution pattern printing and regulate its own weight change, thereby reducing transportation costs.

[0035] 6) The temperature-sensitive memory trainable hydrogel prepared by the present invention has extremely strong stability and extremely low signal attenuation rate for information storage. Using it as a medium for information storage and transmission can reduce the cost required for information storage. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 A schematic diagram of the process of information storage and encryption application of the brain-like trainable memory gel of the present invention;

[0037] Figure 2 A diagram showing the mechanism of forming long-term memory and internal changes of the brain-like memory trainable gel through multiple thermal learning training in the present invention;

[0038] Figure 3 It is a thermal analysis diagram of the improvement of memory proficiency after preview of the brain-like memory trainable gel in the present invention and the two learning processes;

[0039] Figure 4 This is a diagram showing the training of the functionalized brain-like memory trainable gel to physical information such as light, heat, electricity, and force in the present invention;

[0040] Figure 5 A diagram showing the short-term patterned information development and self-erasing process of the brain-like memory trainable gel in the present invention and Example 1;

[0041] Figure 6 This is a diagram of the long-term information storage and encryption process of the brain-like memory trainable gel in the present invention and Example 2;

[0042] Figure 7 The present invention is an example of brain-like memory trainable gel storage music and a schematic diagram of multi-bit information storage and encryption in the present invention and Example 3;

[0043] Figure 8 The present invention is a phase change point image of the brain-like memory trainable gel printed under different laser printing parameters in the present invention and Example 3;

[0044] Fig. 9 This is a graph of volume change and storage information attenuation of the brain-like memory trainable gel in the present invention and Example 4. DETAILED DESCRIPTION

[0045] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0046] It should be noted that, for the convenience of description, only the parts related to the invention are shown in the drawings. In the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other.

[0047] It should be understood that the "system", "device", "unit" and / or "module" used in this application is a method for distinguishing different components, elements, parts, portions or assemblies at different levels. However, if other words can achieve the same purpose, the word can be replaced by other expressions.

[0048] As shown in this application and claims, unless the context clearly indicates an exception, the words "a", "an", "a kind" and / or "the" do not refer to the singular, but also include the plural. Generally speaking, the terms "include" and "comprise" only indicate the inclusion of clearly identified steps and elements, and these steps and elements do not constitute an exclusive list. The method or device may also include other steps or elements. The elements defined by the sentence "includes a..." do not exclude the existence of other identical elements in the process, method, commodity or device that includes the elements.

[0049] In the description of the embodiments of the present application, "plurality" means two or more than two. The following terms "first" and "second" are used for descriptive purposes only and are not to be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0050] In addition, flow charts are used in the present application to illustrate the operations performed by the system according to the embodiments of the present application. It should be understood that the preceding or following operations are not necessarily performed accurately in order. On the contrary, the various steps may be processed in reverse order or simultaneously. At the same time, other operations may also be added to these processes, or a certain step or several steps of operations may be removed from these processes.

[0051] Reference Figure 1 , the MCU sends a pulse width modulation (PWM) signal to the motor control driver to achieve the movement of the three-axis platform. At the same time, the writing laser is also controlled by the MCU to meet the power and time requirements of laser writing. The information written to the gel is collected by the reading laser and encoded by the analog-to-digital converter (ADC). The encoded binary or multi-bit information is then transmitted back to the VLSI, which decrypts the data through the universal asynchronous receiver / transmitter (USART) and controls the music synthesis module to play the information in the data.

[0052] Reference Figure 2 , is a diagram showing the mechanism of forming long-term memory and internal changes of the brain-like memory trainable gel in the present invention after multiple thermal learning trainings, Figure 2 In a, time is the horizontal axis, and the memory retention rate (M% in the calculation formula in Example 4) is the vertical axis, which expresses the change curve of the memory retention rate of the memory gel over time at different thermal learning temperatures. The sudden increase in the memory retention rate during the gradual decrease is caused by thermal learning again. A total of 5 thermal learnings were carried out in the figure, indicating that the memory gel exhibits an Ebbinghaus memory forgetting curve similar to the brain after multiple thermal learnings, and the higher the learning temperature, the higher the memory efficiency. Figure 2 b is the electron paramagnetic resonance spectrum of the gel during the preparation of the memory gel. The formation mechanism of the memory gel was verified by comparing the contents of various free radicals. Figure 3 This is a thermal analysis diagram of the improvement of memory proficiency after pre-study and the two learning processes of the brain-like memory trainable gel in the present invention. Figure 3 a Time is the horizontal axis and memory retention rate is the vertical axis. The figure records the kinetic curve of the memory retention rate of the memory gel during the thermal learning process with or without prior thermal learning. The data show that the memory learning speed of the gel that has been thermally learned in advance is improved when it is thermally learned again. Figure 3 b is Figure 3 a Thermal analysis curves of the two thermal learning processes, with the horizontal axis representing temperature and the vertical axis representing normalized heat flow. By comparing the two thermal analysis curves, it can be observed that the memory gel after thermal learning has an obvious thermal absorption platform before 34°C. Based on this feature, the changes in the internal structure of the gel during thermal learning can be analyzed; Figure 4 This is a diagram showing the training of the functionalized brain-like memory trainable gel to physical information such as light, heat, electricity, and force in the present invention. Figure 4 a, 4b, and 4c respectively show that the mechanical properties, conductivity, and fluorescence intensity change rate of the pre-heat-learned memory gel will be improved under thermal stimulation. Figure 4 d, 4e, and 4f respectively show that the mechanical properties, electrical conductivity, and fluorescence intensity of the memory gel will gradually increase after multiple thermal learning training; Figure 7 This is an example of brain-like memory trainable gel storage music and a schematic diagram of multi-bit information storage and encryption in the present invention and Example 3. Figure 7 a and b are the music spectra stored in the gel. Figure 7 c takes time as the horizontal axis and the laser reading value as the vertical axis. The microcontroller can divide the threshold according to the laser reading value and output a computer language similar to multi-bit 0, 1, 2, 3, etc. Figure 7 d. On this basis, the threshold judgment function can also be edited to edit a richer and more varied output signal to ultimately form an encryption effect.

[0053] Example 1

[0054] Accurately weigh NIPAAm and BIS in a glass bottle containing 3.0 mL of distilled water, add TEMED, place it in an ice water bath and stir it magnetically until it is completely dissolved and the temperature is constant, add APS and stir evenly, transfer the above solution to a culture dish, and place it in a low temperature environment to react.

[0055] The prepared memory gel was first thermally transferred on its surface with a hot copper stamp. The thermal transfer time of "M" was longer than that of "E". After the stamp was transferred, the pattern on the gel surface disappeared and the gel became transparent ( Figure 5 Left 1); then hot water was added to the gel culture dish, and the short-term storage pattern reappeared, with "M" appearing first and "E" appearing later ( Figure 5 2 from left); then the entire gel phase change pattern disappears again ( Figure 5Left 3); as time goes by and the temperature drops, the phase change gradually disappears; then the gel returns to its initial transparent state ( Figure 5 Right (2), after the gel was left to stand at 25°C for a period of time, hot water was injected into the culture dish again. At this time, neither M nor E appeared, but the entire gel phase changed. This figure shows the dynamic short-term memory presentation process of the gel during the three thermal learning processes. After the above gel proficiency improvement and forgetting process were repeated 5 times, the gel working memory ability did not decay.

[0056] Example 2

[0057] Accurately weigh NIPAAm and BIS into a glass bottle containing gold nanorod dispersion, add TEMED, place it in an ice water bath and magnetically stir until it is completely dissolved and kept at a constant temperature, add APS and stir evenly, transfer the above solution to a culture dish, and place it in a low temperature environment for reaction.

[0058] By building a laser writing and reading system, the gel can realize the encoding, storage and encryption of information. When the writing laser writes information on the gel surface, parameters such as laser power, focal length, and writing time have a significant impact on the quality of information writing. Figure 6 As shown in a and b, the degree of gel phase change at the laser focus is proportional to the laser power and writing time, and the value read by the laser reading shows a corresponding regular change. By statistically reading the parameter changes collected by the laser reading and the corresponding laser energy density, it is found that the gel absorbs laser light per unit area and converts it into heat, causing local phase change, and the resulting change in transmittance has an optimal extreme value ( Figure 6 c). By adjusting the writing speed and power, we obtained a series of patterns with a certain three-dimensional effect ( Figure 6 d) The minimum line pitch of the laser writing system used is 100μm.

[0059] By utilizing the properties of gel photothermal conversion to phase change, the laser can be written into the phase change point for encoding, and the laser reading can read the reflected laser value of the phase change point to give the data of the phase change point. The judgment threshold is given in advance, and the phase change area is "1" and the non-phase change area is "0" to achieve data storage. On this basis, the reading path positioning points are written around the phase change point matrix, and correspond one-to-one with the reading laser reading path, so that different encrypted information can be stored in the same data encoding diagram at the same time ( Figure 6 e). We store two different music clips in the same phase change data matrix ( Figure 8a, b), when reading laser reading data, first identify the positioning points around the data matrix, then determine the specific reading path to read the data information, and the read information will eventually play the music clip through the speaker. In this process, the path positioning point is used as a key. If the data needs to be encrypted, the encryptor will edit and write the encrypted information according to the key method. After the target reader obtains the information, he only needs to match it with the laser reading path pre-set by the encryptor (similar to a code book or Enigma machine) to strive to read the laser. The position and number of the reading path positioning points can be edited at will. The huge combination database provides security for writing encrypted information.

[0060] Example 3

[0061] Control the laser writing power and writing time to adjust the size and reflectivity of the phase change point. Divide the data points according to certain thresholds according to the different values ​​read by the laser to achieve binary and multi-base data storage ( Fig. 9 The threshold division can be a fixed value or a dynamic threshold that conforms to a certain mathematical function ( Figure 8 c, d). When writing and reading data, you only need to introduce the encryption function into the threshold judgment program. The laser will adjust the writing laser power, time and other parameters according to the threshold function to print out phase change data dot arrays with different reflectivity. When reading data, the reading laser needs to first perform path positioning point determination, and then perform threshold function determination to finally read the encrypted data. The data storage, encryption and reading system ultimately uses the reading path and threshold function as keys to achieve strong information storage security.

[0062] Example 4

[0063] Since the water content of hydrogel is about 90%, high or low temperature environment often causes volatilization and freezing of gel water, especially high swelling causing problems such as distortion of stored images. The gel was prepared into thin slices and the area changes of swelling and shrinkage were measured. It was found that the area of ​​the gel was proportionally reduced by 76.4% after blast drying at 50°C, and when the gel was equilibrated in a 25°C room temperature water environment, it would return to its initial size. The swelling-shrinkage characteristics of the gel can be used to write information or patterns at higher water contents, and the resolution can be adjusted according to the ambient temperature after volume shrinkage. Taking the 25°C gel as an example, the resolution can be increased to 4.2 times the initial resolution after volume shrinkage ( Fig. 9 a, b, c). Another characteristic brought about by the swelling-contraction behavior of the gel is the change in its own mass. The mass of the dry gel after dehydration is reduced by about 90%. The significant change in volume and mass is more conducive to high-density information storage and preservation. The volume shrinkage of the gel after dehydration is not always proportional. The shrinkage mode of the gel is significantly affected by the drying method, such as Fig. 9As shown in Figure d, the gel evaporates slowly at room temperature in the in-situ synthesis glassware. The circular surface area of ​​the obtained dry gel is exactly the same as that of the glassware. The thickness of the gel sheet is only reduced. The in-situ evaporation drying method ensures a 90% reduction in quality while maintaining the stability of the resolution of the stored information.

[0064] In this example, the gel was first heated at 50°C for 20 minutes, and the change curve of the gel memory retention rate at room temperature with time was recorded. The test wavelength was fixed at 500nm, and the gel memory retention rate changed slightly with the change of ambient temperature ( Fig. 9 e) As the temperature increases, the transmittance decreases and the memory retention rate increases slightly. When the monitoring is continued for 370 days, the memory retention rate remains above 97%. If the water content of the gel is maintained, the stored information may be stably preserved before the polymer decomposes.

[0065] The brain-like trainable memory gel and its information storage and encryption application test method of the present application are as follows:

[0066] (1) Test method for light transmittance of brain-like trainable memory gel:

[0067] The transmittance information of the gel was collected using a UV-visible near-infrared spectrophotometer equipped with a temperature control device. The hydrogel was synthesized in situ in a quartz cuvette. When testing the transmittance change of the gel at different temperatures, the incident light wavelength was fixed at 500nm and the heating and cooling rate was 1℃·min -1 , the temperature control error is ±0.02℃, the cloud point temperature (T cp ) is the temperature at which the gel transmittance is 50%.

[0068] (2) Calculation method of memory retention rate of brain-like trainable memory gel:

[0069] The formula for converting gel transmittance to memory retention is as follows:

[0070]

[0071] Where M is the memory retention rate of the gel, T t is the transmittance of the gel changing with time t, T 0 is the initial transmittance of the gel before learning.

[0072] (3) Test method for memory retention rate of brain-like memory trainable gel:

[0073] The memory retention test of the gel over time was completed using a UV-visible spectrophotometer (Shimadzu, UV-2600). The hydrogel was synthesized in situ in a cuvette, left to stand for 24 hours at 4°C, then studied in a 50°C water bath for 20 minutes and then left to stand at room temperature. The changes in the transmittance of the gel at different wavelengths over time were recorded, with a scanning wavelength of 300 to 900 nm and a scanning temperature of room temperature.

[0074] (4) Calculation method of laser energy used in laser writing:

[0075] The hydrogel was prepared into a circular sheet with a diameter of 10 cm, and information was written into it using a 450nm wavelength laser. At the same time, different patterns were input into it, and the brightness, grayscale and resolution of the pattern could be adjusted by controlling different powers and printing times. The laser writing energy density was calculated as follows:

[0076]

[0077] Among them, E ρ (J) is the laser energy used in the experiment, P t (W) is the full load power of the laser, x% is the actual power percentage used during laser writing, S(um 2 ) is the laser writing focal area, and T is the laser writing time. A laser reading device is used to read the transmittance of the memory point. According to the number of transmittance thresholds set, the information can be edited into different digits to realize information writing and reading of computer languages ​​with different bases.

[0078] In the application, the application process of brain-like trainable memory gel with short-term patterning and self-erasure after development and long-term information storage is as follows:

[0079] (1) Brain-like memory trainable gel short-term pattern information display and self-erasing

[0080] The prepared memory gel was first thermally transferred on its surface with a hot copper stamp. The thermal transfer time of "M" was longer than that of "E". After the stamp was transferred, the pattern on the gel surface disappeared and the gel became transparent ( Figure 5 Left 1); then hot water was added to the gel culture dish, and the short-term storage pattern reappeared, with "M" appearing first and "E" appearing later ( Figure 5 2 from left); then the entire gel phase change pattern disappears again ( Figure 5 Left 3); as time goes by and the temperature drops, the phase change gradually disappears; then the gel returns to its initial transparent state ( Figure 5Right 2), after letting the gel stand in a 25℃ environment for a period of time, hot water was injected into the culture dish again. At this time, neither M nor E appeared, but the entire gel phase changed. This figure shows the dynamic short-term memory presentation process of the gel during the three thermal learning processes. After the above gel proficiency improvement and forgetting process were repeated 5 times, the gel working memory ability did not decay.

[0081] (2) Brain-like memory trainable gel long-term information storage and laser reading, writing and encryption

[0082] During the preparation of MTH hydrogel, a colloidal solution of gold nanorods with photothermal properties is added to give it photothermal properties. Laser irradiation can induce phase change, which is beneficial to the writing and encoding of gel information. We have established a laser writing and reading system, as shown in the figure abstract, which includes a writing laser, a reading laser, a laser sensor, a three-axis platform, a motor control driver, a music synthesis module and a microprogram control unit (VLSI). The writing laser, the reading laser and the MTH hydrogel are fixed on the three-axis platform. The microcontroller sends a pulse width modulation (PWM) signal to the motor control driver to achieve the movement of the three-axis platform. At the same time, the writing laser is also controlled by the microcontroller to meet the power and time requirements of laser writing. The information written into the gel is collected by the reading laser and encoded by an analog-to-digital converter (ADC). The encoded binary information is then transmitted back to the VLSI, which decrypts the data through a universal asynchronous receiver / transmitter (USART) and controls the music synthesis module to play the information in the data.

[0083] The above is a specific description of the preferred implementation of the present invention, but the invention is not limited to the embodiments. Those skilled in the art may make various equivalent modifications or substitutions without violating the spirit of the present invention. These equivalent modifications or substitutions are all included in the scope defined by the claims of this application.

Claims

1. A method for preparing a brain-like trainable memory gel, characterized in that: The following steps are involved: S1. A temperature-sensitive monomer, a functional material, an initiator, and a cross-linking agent are prepared into an aqueous solution, and the aqueous solution is placed in an ice water bath and allowed to stand, wherein the cross-linking agent is N,N'-methylenebisacrylamide, and the initiator is ammonium persulfate; S2. Add a reducing agent, N,N,N',N'-tetramethylethylenediamine, to the aqueous solution described in S1. S3, stirring the solution obtained in S2, transferring the solution to a preset container, and allowing the solution to react for a preset time in a gas environment with a preset oxygen content ratio and temperature environment to obtain a memory gel.

2. The method for preparing a brain-like trainable memory gel according to claim 1, characterized in that: The temperature-sensitive monomer includes, but is not limited to, isopropyl acrylamide, N,N-dimethylaminoethyl methacrylate, vinyl caprolactam, and 2-acrylamide-caprolactam.

3. The method for preparing a brain-like trainable memory gel according to claim 1, characterized in that: The mass fraction of the monomer and water is 3.0% to 70%, and the content of the crosslinking agent is 0 to 8% of the molar ratio of the mixed monomer.

4. The method for preparing a brain-like trainable memory gel according to claim 2, characterized in that: In step S2, when the reagent is added, the aqueous solution is in a stirring state and the temperature is lower than 10° C., and the molar ratio of the reducing agent to the oxidizing agent in the redox free radical initiation system does not exceed 1.

0.

5. The method for preparing a brain-like trainable memory gel according to claim 4, characterized in that: The preset container is a glass container, and the temperature environment in step S3 is 0-25°C.

6. A brain-like trainable memory gel, characterized in that: The brain-like trainable memory gel is prepared by the preparation method of any one of claims 1 to 5.

7. A method for information storage and encryption application, characterized in that: Based on the brain-like trainable memory gel as claimed in claim 6, the method comprises the following steps: Thermally transferring the brain-like trainable memory gel into patterns, and then cooling it down to make the patterns disappear; When heated again, the thermal transfer pattern is developed in a short time.

8. The method for information storage and encryption application according to claim 7, characterized in that: Thermal transfer methods include, but are not limited to, infrared mask exposure writing, laser writing, and thermal stamp transfer.

9. A method for information storage and encryption application, characterized in that: Based on the brain-like trainable memory gel as claimed in claim 6, the method comprises the following steps: Performing patterned laser printing on the brain-like trainable memory gel by using a laser reading and writing system to write information; The laser reading and writing system comprises a writing laser, a reading laser, a laser sensor, a three-axis platform, a motor control driver, a music synthesis module and a microprogram control unit.

10. The method for information storage and encryption application according to claim 9, characterized in that: The information written into the brain-like trainable memory gel is collected by a reading laser and encoded by an analog-to-digital converter; The encoded information is then transmitted back to the microprogrammed control unit; The microprogram control unit decrypts the data and controls the music synthesis module to play the information in the data.

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