Peristaltic pump for herpes zoster virus liquid ultrafiltration and ultrafiltration process

Abstract

The invention discloses a peristaltic pump for herpes zoster virus liquid ultrafiltration and an ultrafiltration process, and relates to the technical field of biological pharmacy, the peristaltic pump comprises an energy-saving motor, a main wheel, a substitute wheel, a vertical seat and a pump pipe, an extension cylinder is fixedly arranged on the rear side face of the vertical seat, and the energy-saving motor is fixedly connected to the side face of the extension cylinder. A group of main wheels and a group of substitute wheels are arranged in the peristaltic pump shell, a switching assembly is arranged in the peristaltic pump shell, the peristaltic pump can creep when the main wheels are in a normal state, and when the main wheels of the peristaltic pump are damaged, a user can quickly move the main wheels away from the creep station through the switching assembly, so that the peristaltic pump is convenient to use. And then the secondary wheel is arranged at a peristaltic station, so that long-time shutdown waiting is avoided, the working continuity and the production efficiency of equipment are effectively improved, the peristaltic pump can be ensured to recover to work as soon as possible when a fault occurs, the dependence on high-skill workers is also reduced, and the maintenance work is simpler and more efficient.

Description

Technical Field

[0001] The invention relates to the technical field of biopharmaceuticals, and in particular to a peristaltic pump for ultrafiltration of herpes zoster virus liquid and an ultrafiltration process. Background Art

[0002] The ultrafiltration of herpes zoster virus fluid requires the use of a peristaltic pump, mainly because the ultrafiltration process requires filtering macromolecules in the virus fluid, such as proteins and virus particles, through a semi-permeable membrane to achieve separation and concentration. The peristaltic pump can provide stable pressure and flow during the ultrafiltration process to ensure that the liquid passes through the ultrafiltration membrane evenly, while effectively promoting the contact between the liquid and the membrane surface, improving the filtration efficiency, maintaining the operating pressure of the membrane, preventing the filtration speed from decreasing, and helping to remove pollutants on the membrane surface, ensuring the continuity and efficiency of the ultrafiltration process.

[0003] A traditional peristaltic pump generally only has one set of pressure wheels inside, and there are usually more than two pressure wheels in this set. When the pressure wheels in this set are damaged and need to be replaced, the peristaltic pump needs to be shut down. Workers first need to remove the old pressure wheels and then install the new pressure wheels into the peristaltic pump. This involves multiple steps and is time-consuming overall, which seriously affects the normal operation of the pump. The disassembly and assembly process requires a high level of professionalism from the workers. Improper operation may cause equipment damage or improper installation, increasing the difficulty and cost of maintenance. Summary of the invention

[0004] The purpose of the present invention is to solve the problem that in the prior art, only one group of pressure wheels is generally provided inside the peristaltic pump, and the group of pressure wheels usually has more than two. When the group of pressure wheels is damaged and needs to be replaced, the peristaltic pump needs to be shut down. The workers first need to remove the old pressure wheels and then install the new pressure wheels into the peristaltic pump. This involves multiple steps and is time-consuming as a whole, which seriously affects the normal operation of the pump. In addition, the disassembly and assembly process requires a high level of professionalism from the workers. Improper operation may cause damage to the equipment or improper installation, which increases the difficulty and cost of maintenance. A peristaltic pump and ultrafiltration process for ultrafiltration of herpes zoster virus liquid are proposed.

[0005] In order to achieve the above object, the present invention adopts the following technical solutions:

[0006] A peristaltic pump for ultrafiltration of herpes zoster virus liquid, comprising an energy-saving motor, a main wheel, a substitute wheel, a vertical seat, and a pump tube, wherein an extension tube is fixedly arranged on the rear side of the vertical seat, the energy-saving motor is fixedly connected to the side of the extension tube, and a limiting assembly capable of fixing and limiting the pump tube is arranged on the side opposite to the energy-saving motor of the vertical seat, the limiting assembly comprises a fixing ring, a left fixing ring, a right fixing ring, and a quick fixing assembly, and the quick fixing assembly realizes quick disassembly and assembly between the left fixing ring and the right fixing ring;

[0007] An extension column is fixedly provided at the output end of the energy-saving motor, and a straight rod is fixedly provided at the end of the extension column. A horizontal cylinder is movably inserted into the straight rod along the horizontal direction, and a rectangular plate is fixedly provided on the outer wall of the horizontal cylinder. The rectangular plate is symmetrically provided with guide grooves along the vertical direction, and a guide column is movably inserted into the guide groove, and a first connecting column and a second connecting column are fixedly provided in sequence on the outer wall of the guide column along the horizontal direction, a main wheel is rotatably connected to the end of the first connecting column, and a substitute wheel is rotatably connected to the end of the second connecting column, and a switching component for switching the main wheel or the substitute wheel to the peristaltic position is provided on the side of the second connecting column, and the switching component includes a pushing cylinder, a driving rod, a limit component and an indication component, and the limit component is used to limit the main wheel or the substitute wheel to the peristaltic position, and the indication component indicates that the main wheel or the substitute wheel is in the peristaltic position.

[0008] Optionally, a left fixing ring is fixedly provided on the side of the vertical seat, and two fixing rings are fixedly provided on one side of the left fixing ring of the vertical seat in the vertical direction, a rectangular groove is provided in the middle position of the side of the left fixing ring, and a rectangular column is fixedly provided on the side of the right fixing ring, and the rectangular column is movably inserted into the rectangular groove, a left fixing groove is provided on the side of the left fixing ring, and a right fixing groove is provided on the side of the right fixing ring, and the quick fixing assembly includes a threaded column, a locking handle, and a quick fixing block.

[0009] Optionally, one end of the threaded column is fixedly connected to the side of the vertical seat, a quick-fix block is movably inserted into the outside of the threaded column, a locking handle is threaded into the end of the outer wall of the threaded column, and a limiting groove is provided on the side of the quick-fix block, and the total width of the limiting groove is greater than the total thickness of the vertical seat, the left fixing ring, and the right fixing ring.

[0010] Optionally, a pushing cylinder is threaded into the outer wall of the horizontal cylinder, an auxiliary nut is fixedly arranged at the end of the outer wall of the pushing cylinder, a receiving groove is opened on the outer wall of the pushing cylinder, a driven ring is rotatably connected inside the accommodating groove, a driving rod is symmetrically rotatably connected to the outer wall of the driven ring, and the remaining end of the driving rod is rotatably connected to the side of the second connecting column.

[0011] Optionally, the limiting assembly includes a limiting cylinder, a first limiting ring, a second limiting ring, and a limiting block. A triangular plate is fixedly provided at one end of the guide column, an extension rod is fixedly provided at the other end of the triangular plate, a limiting block is fixedly provided at the other end of the extension rod, and the limiting cylinder is concentrically fixedly provided on the side of the extension cylinder.

[0012] Optionally, the inner cavity of the limit cylinder is fixedly provided with a first limit ring and a second limit ring in sequence, the distance between the end of the limit cylinder and the first limit ring is equal to the distance between the first limit ring and the second limit ring, the limit block extends into the inner cavity of the limit cylinder, and the width of the limit block is equal to the distance between the first limit ring and the second limit ring.

[0013] Optionally, the indicating assembly includes a U-shaped rod, a positioning column, a first retaining ring, and a second retaining ring. A positioning column is fixedly provided at one end of the straight rod away from the energy-saving motor, and a U-shaped rod is fixedly provided at the end of the horizontal tube. The positioning column passes through the center position of the U-shaped rod, and the positioning column is fixedly provided with a first retaining ring and a second retaining ring on both sides of the U-shaped rod in sequence.

[0014] Optionally, a transparent cover is fixed to the outside of the right fixed ring by bolts, and a center hole is opened at the center position of the side surface of the transparent cover.

[0015] Optionally, rear support frames are symmetrically fixedly arranged on the rear side of the vertical seat, a support seat is fixedly arranged at the bottom between the two rear support frames, and the top of the support seat is fixedly arranged at the bottom of the energy-saving motor.

[0016] An ultrafiltration process for herpes zoster virus liquid comprises the following steps:

[0017] S1, feeding stage:

[0018] The herpes zoster virus liquid is stored in a dedicated sterile storage tank to ensure that the virus liquid is stored under constant low temperature conditions to maintain its activity. The virus liquid is quantitatively transported by the peristaltic pump to enter the ultrafiltration module in the prior art. The speed parameters of the peristaltic pump are set to control the feed flow rate so that the virus liquid enters the ultrafiltration system stably and evenly, thereby ensuring the continuity and stability of the filtration process and avoiding the influence of flow rate fluctuations on the filtration efficiency and the integrity of the virus particles.

[0019] S2, ultrafiltration stage:

[0020] The ultrafiltration module uses hollow fiber ultrafiltration membrane as the core filtration medium. By adjusting the ultrafiltration pressure and transmembrane flow rate, the virus liquid forms a tangential flow on the membrane surface. During this process, the flow, pressure and temperature of the filtrate are monitored in real time to ensure the stability of the ultrafiltration process, and the operating parameters are adjusted in time according to actual conditions to ensure that high-purity and high-concentration virus liquid is obtained.

[0021] Compared with the prior art, the present invention has the following advantages:

[0022] 1. The present invention is provided with a group of main wheels and a group of substitute wheels inside the peristaltic pump housing, and a switching component is provided inside the peristaltic pump housing. When the main wheels are in a normal state, the peristaltic pump performs peristaltic work. When the main wheels of the peristaltic pump are damaged, the user can quickly remove the main wheels from the peristaltic working position through the switching component, and then place the secondary wheels in the peristaltic working position, thereby avoiding long-term downtime waiting, effectively improving the working continuity and production efficiency of the equipment, and ensuring that the peristaltic pump resumes work as soon as possible when a failure occurs, thereby reducing the production interruption time caused by equipment failure, ensuring the efficient operation of the production line, reducing the time of manual disassembly and installation, saving maintenance costs and labor costs, and reducing the dependence on highly skilled workers, making maintenance work simpler and more efficient.

[0023] 2. One of the core components of the switching assembly of the present invention is the limit assembly. First, the limit assembly ensures the correct position of the main wheel, so that the substitute wheel can be accurately moved to the pump pipe waiting position. Such a design ensures the consistency and accuracy of each switching operation, which helps to improve the working efficiency and performance of the equipment. In addition, when the user manipulates the switching assembly, the switching assembly forces the main wheel to move away from the pump pipe first before the main wheel can be moved away, and the substitute wheel then moves to the pump pipe waiting position, which constrains the operation sequence during the switching process, avoids conflict or damage between the main wheel and the pump pipe, ensures that each operation is performed at the predetermined position, and reduces the risk of equipment failure.

[0024] 3. One of the core components of the switching assembly of the present invention is the indicating assembly. The indicating assembly is composed of a purely mechanical structure. The indicating assembly extends from the side of the peristaltic pump housing. When the worker uses the switching assembly to operate the main wheel and the substitute wheel, the main wheel is moved away by the limiting assembly. When the substitute wheel moves to the pump tube position, the worker can use the indicating assembly to quickly determine whether the main wheel or the substitute wheel is in the peristaltic position. The worker can directly understand whether the main wheel or the substitute wheel is in the correct peristaltic position through the indicating assembly. This intuitive indicating method greatly simplifies the operation process, improves the convenience of workers' operation, reduces the difficulty of operation, and reduces the dependence on highly skilled workers, making maintenance work simpler and more efficient. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0026] Figure 2 for Figure 1 Schematic diagram of the semi-exploded structure.

[0027] Figure 3 for Figure 2 Another perspective structural diagram of .

[0028] Figure 4 for Figure 2 Schematic diagram of the top view structure.

[0029] Figure 5 for Figure 1 Another perspective structural diagram of .

[0030] Figure 6 It is a structural schematic diagram of the fast-setting component.

[0031] Figure 7 It is a schematic diagram of the structure of the extension tube and its connecting parts.

[0032] Figure 8 It is a schematic diagram of the structure of the switching component and its connecting parts.

[0033] Fig. 9 It is a schematic diagram of the half-section structure of the limiting cylinder.

[0034] Fig.10 A schematic diagram of the structure of the switching component.

[0035] Fig.11 for Fig.10 Another perspective structural diagram of .

[0036] Fig.12 It is a schematic diagram of the structure of the horizontal cylinder and its connecting parts.

[0037] In the figure: 1, fixing ring; 2, vertical seat; 3, left fixing ring; 4, rectangular groove; 5, right fixing ring; 51, rectangular column; 52, right fixing groove; 53, pump pipe; 6, transparent cover; 61, center hole; 7, rear support frame; 8, energy-saving motor; 81, extension column; 810, straight rod; 9, extension cylinder; 10, support seat; 11, left fixing groove; 12, threaded column; 13, locking grip; 14, fast fixing block; 141, limit groove; 15, limit cylinder; 151, second limit ring; 152 , the first limiting ring; 16, the limiting block; 17, the extension rod; 18, the triangular plate; 19, the guide column; 20, the first connecting column; 21, the second connecting column; 22, the main wheel; 220, the substitute wheel; 23, the driving rod; 24, the pushing cylinder; 241, the receiving groove; 25, the driven ring; 26, the auxiliary nut; 27, the rectangular plate; 271, the guide groove; 28, the horizontal cylinder; 281, the straight groove; 29, the U-shaped rod; 30, the positioning column; 301, the first supporting ring; 302, the second supporting ring. DETAILED DESCRIPTION

[0038] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0039] In the description of the present invention, it is necessary to understand that the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0040] Reference Figure 1-12 A peristaltic pump for ultrafiltration of herpes zoster virus liquid comprises an energy-saving motor 8, a main wheel 22, a substitute wheel 220, a vertical seat 2, and a pump tube 53. An extension tube 9 is fixedly arranged on the rear side of the vertical seat 2, and the energy-saving motor 8 is fixedly connected to the side of the extension tube 9. Selecting the energy-saving motor 8 as the power source of the peristaltic pump can significantly reduce energy consumption, improve operating efficiency, reduce equipment heat generation, and extend service life. The model of the energy-saving motor 8 is a series servo motor such as MSMD012G1U, which has high efficiency and energy-saving characteristics, smooth startup, and high control accuracy. It is suitable for high-requirement scenarios such as ultrafiltration of virus liquid. Compared with traditional motors, the energy-saving motor 8 can reduce energy consumption, reduce operating costs, and has better overload capacity, and is suitable for long-term stable operation. Its low noise and low vibration characteristics help maintain the stability of the laboratory or biopharmaceutical environment.

[0041] A rear support frame 7 is symmetrically fixed on the rear side of the vertical seat 2, a support seat 10 is fixed at the bottom between the two rear support frames 7, and the top of the support seat 10 is fixed at the bottom of the energy-saving motor 8. The rear support frame 7 is used to stably support the vertical seat 2. The vertical seat 2 is provided with a limiting assembly on the opposite side of the energy-saving motor 8 for fixing the pump pipe 53. The limiting assembly includes a fixing ring 1, a left fixing ring 3, a right fixing ring 5 and a quick fixing assembly. The quick fixing assembly realizes quick disassembly and assembly between the left fixing ring 3 and the right fixing ring 5.

[0042] An extension column 81 is fixedly provided at the output end of the energy-saving motor 8, and a straight rod 810 is fixedly provided at the end of the extension column 81. The straight rod 810 is movably inserted into the horizontal cylinder 28 in the horizontal direction. A rectangular plate 27 is fixedly provided on the outer wall of the horizontal cylinder 28. The rectangular plate 27 is symmetrically provided with guide grooves 271 in the vertical direction. A guide column 19 is movably inserted into the guide groove 271. The outer wall of the guide column 19 is fixedly provided with a first connecting column 20 and a second connecting column 21 in sequence in the horizontal direction. The guide column 19 is a rectangular parallelepiped, and the guide column 19 is of the same width as the guide groove 271. A straight groove 281 is provided on the side of the horizontal cylinder 28. The cross-sectional size of the straight groove 281 is the same as that of the straight rod 810. The cooperation between the straight rod 810 and the straight groove 281 can enable the energy-saving motor 8 to drive the structure above the horizontal cylinder 28 to rotate while the horizontal cylinder 28 can move along the axial direction of the straight rod 810.

[0043] The end of the first connecting column 20 is rotatably connected to the main wheel 22, and the end of the second connecting column 21 is rotatably connected to the substitute wheel 220. A switching component for switching the main wheel 22 or the substitute wheel 220 to the peristaltic position is arranged on the side of the second connecting column 21. The switching component includes a pushing cylinder 24, a driving rod 23, a limiting component and an indicating component. The limiting component is used to limit the main wheel 22 or the substitute wheel 220 to the peristaltic position, and the indicating component indicates that the main wheel 22 or the substitute wheel 220 is in the peristaltic position. Since the peristaltic pump for ultrafiltration of viral liquid needs to meet the requirements of corrosion resistance, wear resistance and chemical compatibility, the material of the main wheel 22 and the substitute wheel 220 can be selected as stainless steel, rubber-coated stainless steel, etc.

[0044] A left fixing ring 3 is fixedly provided on the side of the vertical seat 2, a rectangular groove 4 is provided in the middle position of the side of the left fixing ring 3, a rectangular column 51 is fixedly provided on the side of the right fixing ring 5, the rectangular column 51 is movably inserted into the rectangular groove 4, a left fixing groove 11 is provided on the side of the left fixing ring 3, a right fixing groove 52 is provided on the side of the right fixing ring 5, the quick fixing assembly includes a threaded column 12, a locking handle 13, a quick fixing block 14, one end of the threaded column 12 is fixedly connected to the side of the vertical seat 2, a quick fixing block 14 is movably inserted into the outside of the threaded column 12, and the contact part between the threaded column 12 and the quick fixing block 14 is the bare rod part.

[0045] The end of the outer wall of the threaded column 12 is threaded with a locking handle 13, and a limiting groove 141 is provided on the side of the quick-fix block 14. The total width of the limiting groove 141 is greater than the total thickness of the vertical seat 2, the left fixing ring 3, and the right fixing ring 5. The depth and shape of the left fixing groove 11 and the right fixing groove 52 are appropriately set. When the limiting groove 141 of the quick-fix block 14 is inserted into the top of the vertical seat 2, the left fixing ring 3, and the right fixing ring 5, the left fixing ring 3 and the right fixing ring 5 can wrap the outer wall of the pump tube 53, and the inner wall of the pump tube 53 will be exposed, which is convenient for the main The main wheel 22 and the backup wheel 220 are pressed into the inside of the pump tube 53, and the vertical seat 2 is fixedly provided with two fixing rings 1 on one side of the left fixing ring 3 in the vertical direction. The two fixing rings 1 can be used to assist in fixing the two ends of the pump tube 53. When the pump tube 53 needs to be replaced, the locking handle 13 is loosened manually, and the quick-fixing block 14 can rotate around the threaded column 12. The limiting groove 141 of the quick-fixing block 14 is no longer stuck to the top of the vertical seat 2, the left fixing ring 3, and the right fixing ring 5. At this time, the right fixing ring 5 can be separated from the left fixing ring 3.

[0046] A pushing cylinder 24 is threaded into the outer wall of the horizontal cylinder 28, an auxiliary nut 26 is fixedly provided at the end of the outer wall of the pushing cylinder 24, a receiving groove 241 is opened on the outer wall of the pushing cylinder 24, a driven ring 25 is rotatably connected inside the accommodating groove 241, and a driving rod 23 is symmetrically rotatably connected to the outer wall of the driven ring 25, and the remaining end of the driving rod 23 is rotatably connected to the side of the second connecting column 21, and the driving rod 23 is in an inclined state.

[0047] The limiting assembly includes a limiting cylinder 15, a second limiting ring 152, a first limiting ring 151, and a limiting block 16. A triangular plate 18 is fixedly provided at one end of the guide column 19, an extension rod 17 is fixedly provided at the other end of the triangular plate 18, and a limiting block 16 is fixedly provided at the other end of the extension rod 17. The limiting cylinder 15 is concentrically fixedly provided on the side of the extension cylinder 9.

[0048] The inner cavity of the limiting cylinder 15 is fixedly provided with a first limiting ring 152 and a second limiting ring 151 in sequence, the distance between the end of the limiting cylinder 15 and the first limiting ring 152 is equal to the distance between the first limiting ring 152 and the second limiting ring 151, the limiting block 16 extends into the inner cavity of the limiting cylinder 15, the width of the limiting block 16 is equal to the distance between the first limiting ring 152 and the second limiting ring 151, the indicating assembly includes a U-shaped rod 29, a positioning column 30, a first retaining ring 301, and a second retaining ring 302, and a one-shaped rod 810 is fixedly provided with a positioning rod at one end away from the energy-saving motor 8 Column 30, a U-shaped rod 29 is fixedly provided at the end of the horizontal cylinder 28, the positioning column 30 passes through the center of the U-shaped rod 29, and the positioning column 30 is fixedly provided with a first retaining ring 301 and a second retaining ring 302 on both sides of the U-shaped rod 29 in sequence. A transparent cover 6 is fixedly provided on the outside of the right fixed ring 5 with bolts, and a center hole 61 is opened at the center position of the side of the transparent cover 6. The diameter of the center hole 61 needs to be set larger to avoid affecting the rotation of the driving rod 23. The setting of the transparent cover 6 is convenient for users to observe the operating status inside the peristaltic pump housing.

[0049] It should be added that in order to facilitate the rapid disassembly and assembly of the horizontal cylinder 28 and all the structures installed on the horizontal cylinder 28, the second retaining ring 302 can be fixedly connected to the outer wall of the positioning column 30 by bolts. When the horizontal cylinder 28 and all the structures installed on the horizontal cylinder 28 need to be separated from the straight rod 810, the second retaining ring 302 can be removed from the outer wall of the positioning column 30. At this time, the horizontal cylinder 28 and all the structures installed on the horizontal cylinder 28 can be pulled away from the outer wall of the straight rod 810.

[0050] The specific implementation steps and principles of the present invention are as follows:

[0051] When the entire peristaltic pump is in normal operation, the limit block 16 is in the gap between the end of the limit cylinder 15 and the first limit ring 152, and the side of the U-shaped rod 29 is attached to the side of the first retaining ring 301. At this time, the horizontal cylinder 28 cannot move along the axis direction of the straight rod 810, and the main wheel 22 is attached to the inner wall of the pump tube 53. The energy-saving motor 8 drives the main wheels 22 at both ends of the first connecting column 20 to fit to the inner wall of the pump tube 53 through the extension column 81, the straight rod 810, and the horizontal cylinder 28.

[0052] When the user observes that the peristaltic flow of the pump tube 53 is significantly reduced, the energy-saving motor 8 is stopped, the U-shaped rod 29 is held manually, so that the rectangular plate 27 cannot rotate, and the auxiliary nut 26 is rotated counterclockwise by human power. The auxiliary nut 26 drives the first connecting column 20 and the second connecting column 21 to move closer together by driving the push cylinder 24 and the drive rod 23. At this time, the main wheels 22 at both ends of the first connecting column 20 leave the inner wall of the pump tube 53 until the guide column 19 moves to the extreme position of the guide groove 271. The auxiliary nut 26 is difficult to rotate, and the limit block 16 is between the end of the limit cylinder 15 and the first limit ring 152. The horizontal cylinder 28 can be disengaged from the gap between the first and second limit rings 152 and 151, and the horizontal cylinder 28 can be moved along the axial direction of the straight rod 810. The U-shaped rod 29 is pulled by manpower until the U-shaped rod 29 fits against the side of the second abutment ring 302. At this time, the limit block 16 moves to the gap position between the first limit ring 152 and the second limit ring 151, and the substitute wheel 220 moves to the inner ring of the pump tube 53. Finally, the auxiliary nut 26 is rotated in the opposite direction to drive the push cylinder 24 and the drive rod 23 to drive the first connecting column 20 and the second connecting column 21, the two integrated structures, to move away from each other. At this time, the substitute wheels 220 at both ends of the second connecting column 21 fit against and resist the inner wall of the pump tube 53.

[0053] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A peristaltic pump for ultrafiltration of herpes zoster virus liquid, comprising an energy-saving motor, a main wheel, a substitute wheel, a vertical seat, and a pump tube, characterized in that: An extension tube is fixedly arranged on the rear side of the vertical seat, and the energy-saving motor is fixedly connected to the side of the extension tube. A limiting assembly for fixing and limiting the pump pipe is arranged on the side opposite to the energy-saving motor of the vertical seat, and the limiting assembly includes a fixing ring, a left fixing ring, a right fixing ring and a quick fixing assembly, and the quick fixing assembly realizes quick disassembly and assembly between the left fixing ring and the right fixing ring; An extension column is fixedly provided at the output end of the energy-saving motor, and a straight rod is fixedly provided at the end of the extension column. A horizontal cylinder is movably inserted into the straight rod along the horizontal direction, and a rectangular plate is fixedly provided on the outer wall of the horizontal cylinder. The rectangular plate is symmetrically provided with guide grooves along the vertical direction, and a guide column is movably inserted into the guide groove, and a first connecting column and a second connecting column are fixedly provided in sequence on the outer wall of the guide column along the horizontal direction, a main wheel is rotatably connected to the end of the first connecting column, and a substitute wheel is rotatably connected to the end of the second connecting column, and a switching component for switching the main wheel or the substitute wheel to the peristaltic position is provided on the side of the second connecting column, and the switching component includes a pushing cylinder, a driving rod, a limit component and an indication component, and the limit component is used to limit the main wheel or the substitute wheel to the peristaltic position, and the indication component indicates that the main wheel or the substitute wheel is in the peristaltic position.

2. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 1, characterized in that: A left fixing ring is fixedly provided on the side of the vertical seat, and two fixing rings are fixedly provided on one side of the left fixing ring of the vertical seat in the vertical direction. A rectangular groove is provided in the middle position of the side of the left fixing ring, and a rectangular column is fixedly provided on the side of the right fixing ring. The rectangular column is movably inserted into the rectangular groove, a left fixing groove is provided on the side of the left fixing ring, and a right fixing groove is provided on the side of the right fixing ring. The quick fixing assembly includes a threaded column, a locking handle, and a quick fixing block.

3. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 2, characterized in that: One end of the threaded column is fixedly connected to the side of the vertical seat, a quick-fix block is movably inserted into the outside of the threaded column, a locking handle is threaded into the end of the outer wall of the threaded column, and a limiting groove is provided on the side of the quick-fix block, and the total width of the limiting groove is greater than the total thickness of the vertical seat, the left fixing ring, and the right fixing ring.

4. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 1, characterized in that: A pushing cylinder is threaded into the outer wall of the horizontal cylinder, an auxiliary nut is fixedly arranged at the end of the outer wall of the pushing cylinder, a receiving groove is opened on the outer wall of the pushing cylinder, a driven ring is rotatably connected inside the accommodating groove, a driving rod is symmetrically rotatably connected to the outer wall of the driven ring, and the remaining end of the driving rod is rotatably connected to the side of the second connecting column.

5. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 1, characterized in that: The limiting assembly includes a limiting cylinder, a first limiting ring, a second limiting ring, and a limiting block. A triangular plate is fixedly provided at one end of the guide column, an extension rod is fixedly provided at the other end of the triangular plate, a limiting block is fixedly provided at the other end of the extension rod, and the limiting cylinder is concentrically fixedly provided on the side of the extension cylinder.

6. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 5, characterized in that: The inner cavity of the limiting cylinder is fixedly provided with a first limiting ring and a second limiting ring in sequence, the distance between the end of the limiting cylinder and the first limiting ring is equal to the distance between the first limiting ring and the second limiting ring, the limiting block extends into the inner cavity of the limiting cylinder, and the width of the limiting block is equal to the distance between the first limiting ring and the second limiting ring.

7. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 1, characterized in that: The indicating assembly includes a U-shaped rod, a positioning column, a first butt ring, and a second butt ring. The positioning column is fixedly provided at one end of the straight rod away from the energy-saving motor, and the U-shaped rod is fixedly provided at the end of the horizontal tube. The positioning column passes through the center position of the U-shaped rod, and the positioning column is fixedly provided with a first butt ring and a second butt ring on both sides of the U-shaped rod in sequence.

8. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 1, characterized in that: A transparent cover is fixedly arranged on the outside of the right fixed ring by bolts, and a center hole is opened at the center position of the side surface of the transparent cover.

9. A peristaltic pump for ultrafiltration of herpes zoster virus fluid according to claim 1, characterized in that: A rear support frame is symmetrically fixedly arranged on the rear side surface of the vertical seat, a support seat is fixedly arranged at the bottom between the two rear support frames, and the top of the support seat is fixedly arranged at the bottom of the energy-saving motor.

10. An ultrafiltration process for herpes zoster virus liquid, used for a peristaltic pump for ultrafiltration of herpes zoster virus liquid according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1, feeding stage: The herpes zoster virus liquid is stored in a dedicated sterile storage tank, ensuring that the virus liquid is stored under constant low temperature conditions to maintain its activity, and the virus liquid is quantitatively transported by the peristaltic pump to enter the ultrafiltration module in the prior art, and the speed parameter of the peristaltic pump is set to control the feed flow rate so that the virus liquid stably and evenly enters the ultrafiltration system, thereby ensuring the continuity and stability of the filtration process and avoiding the influence of flow rate fluctuations on the filtration efficiency and the integrity of the virus particles; S2, ultrafiltration stage: The ultrafiltration module uses hollow fiber ultrafiltration membrane as the core filtration medium. By adjusting the ultrafiltration pressure and transmembrane flow rate, the virus liquid forms a tangential flow on the membrane surface. During this process, the flow, pressure and temperature of the filtrate are monitored in real time to ensure the stability of the ultrafiltration process, and the operating parameters are adjusted in time according to actual conditions to ensure that high-purity and high-concentration virus liquid is obtained.

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