Independent column oven for liquid chromatography

By setting up partition frames and support blocks in the column temperature box of the liquid chromatography system, and using components such as guide plates and guide blocks to achieve rapid installation and sealing of the liquid chromatography column, the liquid leakage problem caused by loose installation of the liquid chromatography column is solved, and the stability and simplicity of operation are improved.

CN120121766AActive Publication Date: 2025-06-10GUANGDONG SHUNDE ZHONGKE YOULIAN MEDICAL LAB CO LTD

Patent Information

Application Number
CN202510538846.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-27
Publication Date
2025-06-10
Estimated Expiration
2045-04-27

AI Technical Summary

Technical Problem

During the installation of the liquid chromatography system, manual operation can easily lead to loosening of the liquid chromatography column, which in turn causes the pump body to be intimately connected to the column thermostat, resulting in liquid leakage and affecting the separation effect of the sample.

Method used

An independent column thermostat for liquid chromatography was designed. By setting up multiple partition frames and support blocks in the column thermostat, combined with components such as guide plates, guide blocks, fixing rods, installation boxes, etc., the rapid installation and sealing of the liquid chromatography column is achieved to ensure the close connection between the column thermostat and the pump body.

Benefits of technology

This design not only simplifies the installation process of the liquid chromatography column, reduces the complexity of manual operation, but also improves the sealing of the installation, avoids liquid leakage, and ensures the stability and reproducibility of sample separation.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The invention discloses an independent liquid chromatography column oven, and relates to the technical field of column ovens, the independent liquid chromatography column oven comprises a column oven body, the inner side of the column oven body is fixedly connected with a plurality of separation frames, the inner sides of the separation frames are fixedly connected with supporting blocks, the outer sides of the supporting blocks are provided with liquid chromatography columns, and the liquid chromatography columns are arranged on the outer sides of the liquid chromatography columns. Connectors are fixedly connected to the left end and the right end of the liquid chromatographic column, a mounting unit for mounting the liquid chromatographic column is arranged on the inner side of the separation frame, and a fixed cover and a pump body are fixedly connected to the left side of the column oven body. According to the column oven for the independent liquid chromatography, a plurality of separation frames are arranged, a plurality of chromatographic columns are contained, the same instrument and multi-item convenient switching detection are facilitated, and through a guide plate, a guide block, a fixing rod, an installation box, a rotating pipe, installation heads, a second gear piece, a toothed plate and an electric push rod, the installation heads on the left side and the right side are conveniently controlled to rotate and get close to each other; and the liquid chromatographic column is quickly connected with the pump body, so that the workload of workers is reduced, and the operation is simple.
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Description

Technical Field

[0001] The present invention relates to the technical field of column ovens, and particularly to a column oven for independent liquid chromatography. Background Art

[0002] A column oven is a key component in analytical instruments such as high-performance liquid chromatography (HPLC) and gas chromatography (GC), used to precisely control the temperature of the chromatographic column to ensure a stable and reproducible separation process.

[0003] After retrieval, a Chinese patent with the application number "CN202320409462.3" is a column oven for a liquid chromatograph. Experimental personnel install the analytical column to be used according to needs, connect it to the box body through the first pipe sleeve and the second pipe sleeve, and place the first pipe sleeve on the card member in sequence to achieve the preliminary fixation of the analytical column, and it is convenient for the later disassembly and installation of the analytical column.

[0004] When installing the liquid chromatography, it is necessary to connect the liquid chromatography column to the pump body. The pump is the "heart" of the liquid chromatography system, responsible for providing a stable mobile phase flow rate and pressure to push the sample through the chromatographic column for separation. The liquid chromatography column is connected to the pump body through the first sleeve and the second sleeve. When connecting, the staff needs to use a handle to rotate the connectors on both sides so that the connector is installed with the liquid chromatography column in a spiral manner. Manually rotating the connector easily makes the connection too loose, resulting in an insecure connection between the pump body and the liquid chromatography column, and liquid leakage, which is not conducive to the separation of the sample. Summary of the Invention

[0005] In view of the deficiencies of the prior art, the present invention provides a column oven for independent liquid chromatography, which solves the problem that the liquid chromatography column is easily installed loosely when installed manually.

[0006] To achieve the above objectives, the present invention is realized through the following technical solutions:

[0007] A column oven for independent liquid chromatography includes a column oven body. A plurality of partition frames are fixedly connected to the inner side of the column oven body. A support block is fixedly connected to the inner side of the partition frame. A liquid chromatography column is arranged on the outer side of the support block. Connecting heads are fixedly connected to both the left and right ends of the liquid chromatography column. An installation unit for installing the liquid chromatography column is arranged on the inner side of the partition frame. A fixed cover and a pump body are fixedly connected to the left side of the column oven body. A controller is fixedly connected to the front side of the fixed cover. A box door is arranged on the front side of the column oven body. The installation unit includes a connection component and a sealing component.

[0008] Preferably, the connecting component includes a guide plate which is fixedly connected to the inner side of the partition frame and located on the left and right sides of the liquid chromatography column. Guide blocks are slidably connected to the outer sides of the guide plates on both sides. A fixing rod is fixedly connected to the upper side of the guide block, and an installation box is fixedly connected to the upper end of the fixing rod. A rotating pipe and a rotating shaft are rotatably connected to one side of the installation box close to the liquid chromatography column. An installation head is fixedly connected to the outer end of the rotating pipe, a toothed ring is fixedly connected to the outer side of the rotating pipe, and a first gear member meshing with the toothed ring is fixedly connected to the outer side of the rotating shaft. A first bevel gear is fixedly connected to the outer end of the rotating shaft. A front block is fixedly connected to the outer side of the installation box, a control rod is rotatably connected to the front side of the front block, a second bevel gear meshing with the first bevel gear is fixedly connected to the rear end of the control rod, a second gear member is fixedly connected to the front end of the control rod, installation blocks are fixedly connected to the left and right inner walls of the partition frame, and toothed plates meshing with the second gear member are fixedly connected to the outer sides of the installation blocks on both sides.

[0009] Preferably, rotating blocks one are fixedly connected to the outer sides of the guide blocks on both sides, inclined plates are rotatably connected to the outer sides of the rotating blocks one on both sides, rotating blocks two are rotatably connected to the outer sides of the inclined plates, a push plate is fixedly connected to the front side of the rotating block two, and an electric push rod is fixedly connected between the rear side of the push plate and the inner wall of the partition frame.

[0010] Preferably, internal threads are provided on the inner side of the connecting head, and external threads adapted to the internal threads are provided on the outer side of the installation head.

[0011] Preferably, a sealing cover is fixedly connected to the outer side of the installation head. The sealing component includes a sealing airbag which is fixedly connected to the inner side of the sealing cover. A plurality of connecting channels are provided on the inner side of the rotating pipe, branch pipes are fixedly connected between the connecting channels and the sealing airbag. A fixed cavity is fixedly connected to the inner side of the installation box, through holes are provided on the inner side of the fixed cavity and the inner wall of the installation box. An air box is fixedly connected to the inner side of the partition frame, a piston plate is provided on the inner side of the air box, a moving rod is fixedly connected to the outer side of the piston plate, the outer end of the moving rod passes through the right side of the air box and is fixedly connected to a connecting block, the connecting block is fixedly connected to the guide block, and a conveying pipe is fixedly connected between the air box and the fixed cavity. The piston plate and the moving rod are both slidably connected to the air box.

[0012] Preferably, a liquid inlet pipe is fixedly connected to the left side of the left installation box, connecting pipes are fixedly connected to the outer ends of the liquid inlet pipes, a fixed pipe is fixedly connected between the connecting pipe and the pump body. An outlet pipe is fixedly connected to the right side of the right installation box, a second solenoid valve is provided on the outer side of the outlet pipe, and a first solenoid valve is provided on the outer side of the liquid inlet pipe.

[0013] Preferably, the outer ends of the liquid inlet pipe and the outlet pipe both pass through the outer side of the column temperature box body.

[0014] Beneficial effects:

[0015] The present invention provides an oven for an independent liquid chromatography. Compared with the prior art, it has the following

[0016] Beneficial effects:

[0017] (1) For the oven for the independent liquid chromatography, by providing a plurality of partition frames to accommodate multiple chromatographic columns, it is convenient for a single instrument to quickly switch and detect multiple items. And through the guide plate, guide block, fixed rod, installation box, rotating pipe, installation head, second gear member, toothed plate and electric push rod, it is convenient to control the rotation and mutual approach of the installation heads on both sides, so that the liquid chromatography column can be quickly connected to the pump body, reducing the workload of the staff and having simple operation.

[0018] (2) For the oven for the independent liquid chromatography, by providing a sealing cover, sealing airbag, air box, piston plate, moving rod, connecting block and delivery pipe, when installing the liquid chromatography column, it is convenient to make the sealing airbag expand, and cooperate with the sealing cover to increase the sealing performance of the installation of the liquid chromatography column and avoid liquid leakage. Description of the drawings

[0019] Figure 1 is the overall three-dimensional structure diagram of the present invention;

[0020] Figure 2 is the partial three-dimensional structure diagram of the present invention;

[0021] Figure 3 is the three-dimensional structure diagram of the partition frame in the present invention;

[0022] Figure 4 is the three-dimensional structure diagram of the installation unit in the present invention;

[0023] Figure 5 is the partial three-dimensional structure diagram of the installation unit in the present invention;

[0024] Figure 6 is Figure 5 the enlarged view at A in

[0025] Figure 7 is the partial sectional three-dimensional structure diagram of the installation unit in the present invention;

[0026] Figure 8 is the partial sectional three-dimensional structure diagram of the sealing component in the present invention;

[0027] Figure 9 is the three-dimensional structure diagram of the liquid chromatography column in the present invention.

[0028] In the figure: 1, column temperature box body; 2, partition frame; 3, box door; 4, support block; 5, liquid chromatography column; 6, installation unit; 7, fixing cover; 8, controller; 9, liquid inlet pipe; 10, solenoid valve I; 11, connecting pipe; 12, pump body; 13, fixing pipe; 14, liquid outlet pipe; 15, solenoid valve II; 16, connector; 17, internal thread; 61, connecting component; 62, sealing component;

[0029] 611, guide plate; 612, guide block; 613, rotating block I; 614, inclined plate; 615, rotating block II; 616, pushing plate; 617, electric push rod; 618, fixing rod; 619, installation box; 6110, toothed plate; 6111, installation block; 6112, rotating pipe; 6113, toothed ring; 6114, rotating shaft; 6115, gear part I; 6116, bevel gear I; 6117, bevel gear II; 6118, control rod; 6119, front block; 6120, gear part II; 6121, installation head; 6122, sealing cover;

[0030] 621, sealing airbag; 622, branch pipe; 623, connecting channel; 624, through hole; 625, fixing cavity; 626, air box; 627, piston plate; 628, moving rod; 629, connecting block; 6210, conveying pipe. Specific implementation manner

[0031] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0032] Embodiment 1

[0033] Please refer to Figure 1 - Figure 6 、 Figure 9, the present invention provides a technical solution: an independent column oven for liquid chromatography, which includes a column oven body 1. A plurality of partition frames 2 are fixedly connected to the inner side of the column oven body 1. A support block 4 is fixedly connected to the inner side of the partition frame 2. A liquid chromatography column 5 is arranged on the outer side of the support block 4. Connection heads 16 are fixedly connected to both the left and right ends of the liquid chromatography column 5. An installation unit 6 for installing the liquid chromatography column 5 is arranged on the inner side of the partition frame 2. A fixed cover 7 and a pump body 12 are fixedly connected to the left side of the column oven body 1. A controller 8 is fixedly connected to the front side of the fixed cover 7. A door 3 is arranged on the front side of the column oven body 1. The installation unit 6 includes a connection component 61 and a sealing component 62. An inlet pipe 9 is fixedly connected to the left side of the left installation box 619. Connection pipes 11 are fixedly connected to the outer ends of a plurality of inlet pipes 9. A fixed pipe 13 is fixedly connected between the connection pipe 11 and the pump body 12. An outlet pipe 14 is fixedly connected to the right side of the right installation box 619. A solenoid valve II 15 is arranged on the outer side of the outlet pipe 14. A solenoid valve I 10 is arranged on the outer side of the inlet pipe 9. The outer ends of the inlet pipe 9 and the outlet pipe 14 both pass through the outer side of the column oven body 1. When in use, through the plurality of partition frames 2, it is convenient to accommodate a plurality of liquid chromatography columns 5. Each liquid chromatography column 5 has an independent space, which is convenient for multi-project convenient switching detection on the same instrument, improves the utilization rate of the instrument machine time, and through the installation unit 6, it is convenient to quickly connect the liquid chromatography column 5 with the pump body 12 together. By setting the solenoid valve I 10 and the solenoid valve II 15, it is convenient to control the cooperation between the liquid chromatography column 5 and the pump body 12.

[0034] The connecting component 61 includes a guide plate 611. The guide plate 611 is fixedly connected to the inner side of the partition frame 2 and is located on the left and right sides of the liquid chromatography column 5. Guide blocks 612 are slidably connected to the outer sides of the guide plates 611 on the left and right sides. A fixed rod 618 is fixedly connected to the upper side of the guide block 612. The upper end of the fixed rod 618 is fixedly connected to an installation box 619. A rotating pipe 6112 and a rotating shaft 6114 are rotatably connected to one side of the installation box 619 close to the liquid chromatography column 5. An installation head 6121 is fixedly connected to the outer end of the rotating pipe 6112. A toothed ring 6113 is fixedly connected to the outer side of the rotating pipe 6112. A first gear member 6115 engaged with the toothed ring 6113 is fixedly connected to the outer side of the rotating shaft 6114. A first bevel gear 6116 is fixedly connected to the outer end of the rotating shaft 6114. A front block 6119 is fixedly connected to the outer side of the installation box 619. A control rod 6118 is rotatably connected to the front side of the front block 6119. A second bevel gear 6117 engaged with the first bevel gear 6116 is fixedly connected to the rear end of the control rod 6118. A second gear member 6120 is fixedly connected to the front end of the control rod 6118. Installation blocks 6111 are fixedly connected to the left and right inner walls of the partition frame 2. Rack plates 6110 engaged with the second gear member 6120 are fixedly connected to the outer sides of the installation blocks 6111 on the left and right sides. First rotating blocks 613 are fixedly connected to the outer sides of the guide blocks 612 on the left and right sides. Inclined plates 614 are rotatably connected to the outer sides of the first rotating blocks 613 on the left and right sides. Second rotating blocks 615 are rotatably connected to the outer sides of the inclined plates 614. A push plate 616 is fixedly connected to the front side of the second rotating block 615. An electric push rod 617 is fixedly connected between the rear side of the push plate 616 and the inner wall of the partition frame 2. An internal thread 17 is provided on the inner side of the connecting head 16. An external thread adapted to the internal thread 17 is provided on the outer side of the installation head 6121.

[0035] When installing the liquid chromatography column 5, place the liquid chromatography column 5 on the support block 4, then manually press and limit the liquid chromatography column 5, and then control the electric push rod 617 to drive the push plate 616 to move forward. The push plate 616 drives the inclined plate 614 to rotate. Since the two inclined plates 614 are symmetrically distributed, the inclined plate 614 drives the guide block 612 to move. The guide blocks 612 on both sides approach each other. The guide block 612 drives the fixed rod 618 to move, the fixed rod 618 drives the installation box 619 to move, the installation box 619 drives the rotating pipe 6112 to move, and the rotating pipe 6112 drives the installation head 6121 to move, so that the installation head 6121 approaches the connector 16 on the liquid chromatography column 5. At the same time, the installation box 619 drives the control rod 6118 on the front block 6119 to move, and the control rod 6118 drives the second gear part 6120 to move. Since the second gear part 6120 is meshed with the toothed plate 6110, the second gear part 6120 drives the control rod 6118 to rotate. The control rod 6118 drives the second bevel gear 6117 to rotate, the second bevel gear 6117 drives the first bevel gear 6116 to rotate, the first bevel gear 6116 drives the rotating shaft 6114 to rotate, the rotating shaft 6114 drives the first gear part 6115 to rotate, the first gear part 6115 drives the toothed ring 6113 to rotate, and the toothed ring 6113 drives the rotating pipe 6112 to rotate. The rotating pipe 6112 drives the installation head 6121 to rotate, so that the installation head 6121 rotates while approaching the liquid chromatography column 5, and the installation head 6121 is screwed together with the connector 16 on the liquid chromatography column 5, which is convenient to quickly connect the liquid chromatography column 5 with the pump body 12.

[0036] Embodiment 2

[0037] On the basis of Embodiment 1, as Figure 7 , Figure 8 shown, an independent column oven for liquid chromatography includes a column oven body 1. A plurality of partition frames 2 are fixedly connected to the inner side of the column oven body 1. A support block 4 is fixedly connected to the inner side of the partition frame 2. A liquid chromatography column 5 is arranged on the outer side of the support block 4. Connectors 16 are fixedly connected to both the left and right ends of the liquid chromatography column 5. An installation unit 6 for installing the liquid chromatography column 5 is arranged on the inner side of the partition frame 2. A fixed cover 7 and a pump body 12 are fixedly connected to the left side of the column oven body 1. A controller 8 is fixedly connected to the front side of the fixed cover 7. A door 3 is arranged on the front side of the column oven body 1. The installation unit 6 includes a connection assembly 61 and a sealing assembly 62. A liquid inlet pipe 9 is fixedly connected to the left side of the left installation box 619. Connection pipes 11 are fixedly connected to the outer ends of the plurality of liquid inlet pipes 9. A fixed pipe 13 is fixedly connected between the connection pipe 11 and the pump body 12. A liquid outlet pipe 14 is fixedly connected to the right side of the right installation box 619. A solenoid valve II 15 is arranged on the outer side of the liquid outlet pipe 14. A solenoid valve I 10 is arranged on the outer side of the liquid inlet pipe 9. The outer ends of the liquid inlet pipe 9 and the liquid outlet pipe 14 pass through the outer side of the column oven body 1.

[0038] A sealing cover 6122 is fixedly connected to the outer side of the mounting head 6121. The sealing assembly 62 includes a sealing airbag 621, and the sealing airbag 621 is fixedly connected to the inner side of the sealing cover 6122. A plurality of connecting channels 623 are arranged inside the rotating pipe 6112. A branch pipe 622 is fixedly connected between the connecting channel 623 and the sealing airbag 621. A fixed cavity 625 is fixedly connected to the inner side of the mounting box 619. Through holes 624 are formed in the inner side of the fixed cavity 625 and the inner wall of the mounting box 619. An air box 626 is fixedly connected to the inner side of the partition frame 2. A piston plate 627 is arranged inside the air box 626. A moving rod 628 is fixedly connected to the outer side of the piston plate 627. The outer end of the moving rod 628 passes through the right side of the air box 626 and is fixedly connected to a connecting block 629. The connecting block 629 is fixedly connected to the guide block 612. A delivery pipe 6210 is fixedly connected between the air box 626 and the fixed cavity 625. The piston plate 627 and the moving rod 628 are both slidably connected to the air box 626. When installing the liquid chromatography column 5, the guide block 612 drives the connecting block 629 to move, the connecting block 629 drives the moving rod 628 to move, the moving rod 628 drives the piston plate 627 to move, the piston plate 627 pushes the gas in the air box 626 out, and through the delivery pipe 6210, the gas in the air box 626 is delivered into the fixed cavity 625, and through the through holes 624, the connecting channels 623 and the branch pipe 622, the gas is delivered into the sealing airbag 621. The sealing airbag 621 expands, which facilitates the sealing airbag 621 to seal the connecting head 16, makes the connection of the liquid chromatography column 5 more tight, avoids liquid leakage, and through the sealing cover 6122, the sealing cover 6122 catches the connecting head 16, increasing the connection stability.

[0039] Working principle: When in use, the staff first places the liquid chromatography column 5 on the support block 4 and uses their hand to limit the liquid chromatography column 5. Then, the electric push rod 617 is controlled to push the push plate 616 to move. Under the action of the inclined plate 614, the guide block 612, the fixed rod 618, the mounting box 619, and the rotating pipe 6112, the mounting heads 6121 on the left and right sides are controlled to approach each other. At the same time, the mounting box 619 drives the second gear member 6120 to move. Under the action of the toothed plate 6110, the control rod 6118, the second bevel gear 6117, the first bevel gear 6116, the rotating shaft 6114, the first gear member 6115, and the toothed ring 6113, the mounting head 6121 is controlled to rotate, so that the mounting head 6121 is threadedly connected to the connecting head 16, which facilitates the rapid installation of the liquid chromatography column 5. At the same time, the guide block 612 drives the connecting block 629 to move. Under the action of the moving rod 628, the piston plate 627, the air box 626, the delivery pipe 6210, the fixed cavity 625, the connecting channels 623, and the branch pipe 622, the sealing airbag 621 expands, which facilitates the sealing operation of the sealing airbag 621 on the connecting head 16, increases the sealing performance of the connection of the liquid chromatography column 5, and avoids liquid leakage.

[0040] It should be noted that in this text, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or further includes elements inherent to such process, method, article or device.

[0041] Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A stand-alone column oven for liquid chromatography, comprising a column oven body (1), characterized in that: A plurality of partition frames (2) are fixedly connected to the inner side of the column temperature box (1), a support block (4) is fixedly connected to the inner side of the partition frame (2), a liquid chromatography column (5) is arranged on the outer side of the support block (4), both left and right ends of the liquid chromatography column (5) are fixedly connected to connectors (16), an installation unit (6) for installing the liquid chromatography column (5) is arranged on the inner side of the partition frame (2), a fixed cover (7) and a pump body (12) are fixedly connected to the left side of the column temperature box (1), a controller (8) is fixedly connected to the front side of the fixed cover (7), a box door (3) is arranged on the front side of the column temperature box (1), and the installation unit (6) comprises a connection component (61) and a sealing component (62).

2. The independent column oven for liquid chromatography according to claim 1, characterized in that: The connecting assembly (61) comprises a guide plate (611), wherein the guide plate (611) is fixedly connected to the inner side of the partition frame (2) and is located on the left and right sides of the liquid chromatography column (5); guide blocks (612) are slidably connected to the outer sides of the guide plates (611) on the left and right sides; a fixing rod (618) is fixedly connected to the upper side of the guide block (612); an installation box (619) is fixedly connected to the upper end of the fixing rod (618); a rotating tube (6112) and a rotating shaft (6114) are rotatably connected to the side of the installation box (619) close to the liquid chromatography column (5); a mounting head (6121) is fixedly connected to the outer end of the rotating tube (6112); a gear ring (6113) is fixedly connected to the outer side of the rotating tube (6112); and a gear ring (6114) is fixedly connected to the outer side of the rotating shaft (6114). A gear member 1 (6115) meshingly connected to the gear ring (6113); the outer end of the rotating shaft (6114) is fixedly connected to a bevel gear 1 (6116); the outer side of the mounting box (619) is fixedly connected to a front block (6119); the front side of the front block (6119) is rotatably connected to a control rod (6118); the rear end of the control rod (6118) is fixedly connected to a bevel gear 2 (6117) meshingly connected to the bevel gear 1 (6116); the front end of the control rod (6118) is fixedly connected to a gear member 2 (6120); the left and right inner walls of the partition frame (2) are fixedly connected to mounting blocks (6111); the outer sides of the mounting blocks (6111) on the left and right sides are fixedly connected to toothed plates (6110) meshingly connected to the gear member 2 (6120).

3. The independent column oven for liquid chromatography according to claim 2, characterized in that: The outer sides of the guide blocks (612) on the left and right sides are fixedly connected with rotating blocks 1 (613), the outer sides of the rotating blocks 1 (613) on the left and right sides are rotatably connected with inclined plates (614), the outer sides of the inclined plates (614) are rotatably connected with rotating blocks 2 (615), the front side of the rotating blocks 2 (615) is fixedly connected with a push plate (616), and the rear side of the push plate (616) and the inner wall of the partition frame (2) are fixedly connected with an electric push rod (617).

4. The independent column oven for liquid chromatography according to claim 2, characterized in that: The inner side of the connecting head (16) is provided with an internal thread (17), and the outer side of the mounting head (6121) is provided with an external thread matching the internal thread (17).

5. The independent column oven for liquid chromatography according to claim 2, characterized in that: The outer side of the installation head (6121) is fixedly connected to a sealing cover (6122); the sealing assembly (62) includes a sealing airbag (621); the sealing airbag (621) is fixedly connected to the inner side of the sealing cover (6122); a plurality of connecting channels (623) are provided on the inner side of the rotating tube (6112); a branch pipe (622) is fixedly connected between the connecting channel (623) and the sealing airbag (621); the inner side of the installation box (619) is fixedly connected to a fixed cavity (625); the inner side of the fixed cavity (625) and the inner wall of the installation box (619) are both provided with through holes (624) ), the inner side of the partition frame (2) is fixedly connected to an air box (626), the inner side of the air box (626) is provided with a piston plate (627), the outer side of the piston plate (627) is fixedly connected to a moving rod (628), the outer end of the moving rod (628) passes through the right side of the air box (626) and is fixedly connected to a connecting block (629), the connecting block (629) is fixedly connected to the guide block (612), a delivery pipe (6210) is fixedly connected between the air box (626) and the fixed cavity (625), and the piston plate (627) and the moving rod (628) are both slidably connected to the air box (626).

6. The independent column oven for liquid chromatography according to claim 2, characterized in that: The left side of the installation box (619) on the left side is fixedly connected to a liquid inlet pipe (9), the outer ends of the plurality of liquid inlet pipes (9) are fixedly connected to connecting pipes (11), a fixing pipe (13) is fixedly connected between the connecting pipe (11) and the pump body (12), the right side of the installation box (619) on the right side is fixedly connected to a liquid outlet pipe (14), the outer side of the liquid outlet pipe (14) is provided with a second solenoid valve (15), and the outer side of the liquid inlet pipe (9) is provided with a first solenoid valve (10).

7. The independent column oven for liquid chromatography according to claim 6, characterized in that: The outer ends of the liquid inlet pipe (9) and the liquid outlet pipe (14) both pass through the outside of the column temperature box (1).

Citation Information

Patent Citations

  • Column oven for liquid chromatograph

    CN219417358U

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    CN116026973A

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    CN117871758A

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