Lymphatic system inspection device

By designing a lymph system inspection device including a placement part, an illumination part and an imaging part, the problem of limited excitation light and fluorescence detection ranges when inspecting the lower body lymph system of the subject in the art is solved, and efficient and accurate lymph system inspection is achieved.

CN120129499APending Publication Date: 2025-06-10HAMAMATSU PHOTONICS KK
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Patent Information

Application Number
CN202380076509.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2022-11-04
Filing Date
2023-06-07
Publication Date
2025-06-10

AI Technical Summary

Technical Problem

When the existing lymphatic system examination device examines the lower body lymphatic system of the subject, the excitation light and fluorescence detection range is limited, making it difficult to conduct efficient examinations.

Method used

A lymphatic system inspection device is designed, including a main body part, a lighting part and an imaging part. The main body part has a mounting part and a support part, which is used for standing by the subject to be tested, and the support part supports the lighting and the imaging part. The illumination unit irradiates the lower body of the subject to be tested, and the imaging unit detects and records the fluorescent signal. The positioning part and the restricting part ensure that the lighting and imaging part are consistent with the lower body position of the subject to be measured, and reduce the influence of interfering light.

Benefits of technology

通过该装置,能够有效地进行被测者下半身淋巴系统的检查,获得清晰的荧光像,提高了检查的效率和准确性。

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Abstract

This lymphatic system inspection device is provided with: a main body part which has a placement part on which a subject having a fluorescent dye injected into the lymphatic system stands, and in which the lower body of the subject is positioned in an imaging region on the placement part; an illumination unit that irradiates excitation light to the lower body; and an imaging unit that detects fluorescence emitted from the lower body in response to the irradiation of the excitation light. A positioning part indicating the standing position of the subject is arranged on the carrying part.
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Description

Technical Field

[0001] The present disclosure relates to a lymphatic system inspection device. Background Art

[0002] The lymphatic system is a network that functions as a circulatory system of lymph fluid and is composed of lymph nodes, lymphatic vessels, etc. As a method for diagnosing diseases of the lymphatic system (such as lymphedema), there is known a method of irradiating an excitation light to a predetermined site of a subject into whom a fluorescent dye such as indocyanine green has been injected into the lymphatic system, detecting fluorescence emitted from the predetermined site according to the irradiation of the excitation light, and obtaining a fluorescence image of the predetermined site (for example, refer to Patent Document 1). Prior Art Documents Patent Documents

[0003] Patent Document 1: Japanese Patent Application Laid-Open No. 2019-118803 Summary of the Invention Problems to be Solved by the Invention

[0004] For the device used in the above-described inspection, there is a problem that the irradiation range of the excitation light and the detection range of the fluorescence are limited to a narrow range, and it is difficult to efficiently perform the inspection of the lymphatic system of the lower body of the subject.

[0005] An object of the present disclosure is to provide a lymphatic system inspection device suitable for inspecting the lymphatic system of the lower body of a subject. Technical Means for Solving the Problems

[0006] One aspect of the lymphatic system inspection device of the present disclosure is [1] "a lymphatic system inspection device comprising: a main body portion having a placement portion on which a subject into whom a fluorescent dye has been injected into the lymphatic system stands, and a imaging region in which the lower body of the subject is located on the placement portion; an illumination portion that irradiates the lower body with excitation light; and an imaging portion that detects fluorescence emitted from the lower body according to the irradiation of the excitation light, and a positioning portion indicating the standing position of the subject is provided on the placement portion".

[0007] In the lymphatic system inspection system described in the above [1], a positioning portion indicating the standing position of the subject is provided on the placement portion on which the subject stands. Thereby, the distance between the illumination portion and the lower body of the subject and the distance between the imaging portion and the lower body of the subject can be maintained constant, and the orientation of the subject's feet with respect to the illumination portion and the imaging portion can be made consistent with a predetermined orientation. Thus, according to the lymphatic system inspection device described in the above [1], a suitable fluorescence image of the lower body for inspecting the lymphatic system of the lower body of the subject can be obtained.

[0008] One aspect of the lymphatic system inspection device of the present disclosure may also be "[2] the lymphatic system inspection device described in [1], wherein the positioning unit includes the foot shape when the subject faces the imaging unit side and the foot shape when the subject faces the opposite side of the imaging unit". According to the lymphatic system inspection device described in [2], in each of the states where the subject faces the imaging unit side and the state where the subject faces the opposite side of the imaging unit, the orientation of the subject's feet relative to the illumination unit and the imaging unit can be made consistent with a specified orientation.

[0009] One aspect of the lymphatic system inspection device of the present disclosure may also be "[3] the lymphatic system inspection device described in the above [1] or [2], wherein the main body portion further has: a support portion that supports the illumination unit and the imaging unit; and a wall portion that forms a frame that divides the imaging area and houses the illumination unit and the imaging unit, and an opening for disposing the subject is formed in the wall portion". According to the lymphatic system inspection device described in [3], the influence of interfering light can be suppressed and a fluorescence image of the lower body of the subject can be obtained.

[0010] One aspect of the lymphatic system inspection device of the present disclosure may also be "[4] the lymphatic system inspection device described in the above [3], further comprising: a cover that covers the opening in a state worn by the subject". According to the lymphatic system inspection device described in [4], the influence of interfering light can be more reliably suppressed and a fluorescence image of the lower body of the subject can be obtained.

[0011] One aspect of the lymphatic system inspection device of the present disclosure may also be "[5] the lymphatic system inspection device described in the above [3] or [4], wherein the wall portion includes a first wall portion mounted on the placement portion and a second wall portion mounted on the support portion, and the support portion and the second wall portion are detachable from the placement portion and the first wall portion". According to the lymphatic system inspection device described in [5], the portability of the lymphatic system inspection device can be improved.

[0012] One aspect of the lymphatic system inspection device of the present disclosure may also be "[6] the lymphatic system inspection device described in any one of the above [3] to [5], further comprising a camera that photographs the positioning unit". According to the lymphatic system inspection device described in [6], when it is difficult for the subject to directly visually observe the positioning unit, the subject can also visually observe the image obtained by the camera and make the standing position consistent with the positioning unit. Effects of the Invention

[0013] According to the present disclosure, a lymphatic system inspection device suitable for inspecting the lymphatic system of the lower body of a subject can be provided. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 is a perspective view of a lymphatic system inspection apparatus according to an embodiment. Figure 2 is Figure 1 a perspective view of the apparatus main body shown. Figure 3 is along Figure 2 a sectional view of the apparatus main body taken along line III-III shown. Figure 4 is along Figure 3 a sectional view of the apparatus main body taken along line IV-IV shown. Figure 5 is along Figure 3 a sectional view of the apparatus main body taken along line V-V shown. Figure 6 is Figure 2 a sectional view of the restricting portion shown. Figure 7 is a sectional view of the apparatus main body in which a second plate for brightness correction is disposed. Figure 8 is a view showing a visible light image of an object. Figure 9 is a view showing a display unit that displays a plurality of fluorescence images of an object Figure 8 shown. Figure 10 is a top view of the apparatus main body of a modified example. Detailed Description of the Invention

[0015] Hereinafter, embodiments of the present disclosure will be described in detail with reference to the accompanying drawings. In addition, the same or corresponding parts are denoted by the same reference numerals in each figure, and redundant description is omitted.

[0016] Figure 1 The lymphatic system inspection apparatus 1 shown is an apparatus for inspecting the lymphatic system of the lower body of a subject S for diagnosing diseases of the lymphatic system (for example, lymphedema). More specifically, the lymphatic system inspection apparatus 1 is an apparatus that irradiates the lower body of a subject S in which a fluorescent dye such as indocyanine green is injected into the lymphatic system with excitation light, detects the fluorescence emitted from the lower body according to the irradiation of the excitation light, and obtains a fluorescence image of the lower body. Hereinafter, the vertical direction will be referred to as the Z direction, the first horizontal direction will be referred to as the X direction, and the second horizontal direction perpendicular to the first horizontal direction will be referred to as the Y direction.

[0017] As Figure 1As shown, the lymphatic system examination device 1 includes a device main body 10, a control unit 11, a display unit 12, and an input unit 13. The control unit 11 is composed of a processing unit and a storage unit. The processing unit of the control unit 11 is a computer device composed of a processor, a memory, a storage device, a communication device, etc., and processes various data by executing software (program). The storage unit of the control unit 11 is a hard disk or the like, and stores various data. The display unit 12 is a display or the like, and displays various data to the operator. The input unit 13 is a mouse, a keyboard, etc., and accepts the input of various data from the operator.

[0018] As Figure 2 , Figure 3 , Figure 4 and Figure 5 shown, the device main body 10 includes a main body portion 2. The main body portion 2 has a placement portion 21 and a support portion 22. In the main body portion 2, the placement portion 21 is the part where the subject S stands, and the support portion 22 is the part disposed on one side in the X direction with respect to the placement portion 21. The main body portion 2 places the lower body L of the subject S (that is, the part from the lower abdomen to the toes) in the imaging area R on the placement portion 21. A plurality of casters 23 are installed on the lower surfaces of each of the placement portion 21 and the support portion 22. Thus, the device main body 10 can move smoothly.

[0019] The main body portion 2 further has a frame 24 and a wall portion 25. The frame 24 is composed of a first frame 241 and a second frame 242. The first frame 241 is installed on the placement portion 21, and the second frame 242 is installed on the support portion 22. The wall portion 25 is composed of a first wall portion 251 and a second wall portion 252. The first wall portion 251 is installed on the placement portion 21 via the first frame 241, and the second wall portion 252 is installed on the support portion 22 via the second frame 242. The unit composed of the support portion 22, the second frame 242, and the second wall portion 252 can be detached from and attached to the unit composed of the placement portion 21, the first frame 241, and the first wall portion 251. As an example, the width of each unit in the X direction and the width of each unit in the Y direction are 70 cm or less. Thus, the portability of each unit can be improved.

[0020] The wall portion 25 forms a frame body 250 on the placement portion 21 and the support portion 22. The frame body 250 divides the imaging area R on the placement portion 21. In the frame body 250, an opening 25a is formed so as to face the placement portion 21 across the imaging area R. The waist portion of the subject S is located inside the opening 25a. That is, an opening 25a for disposing the subject S inside is formed in the wall portion 25. The inner surface of the frame body 250 is, for example, set to black. In addition, in the first wall portion 251, a door is formed by a wall portion 251a on the side opposite to the second wall portion 252. Thus, the subject S can move up and down with respect to the placement portion 21.

[0021] The main body 2 also has a restricting portion 26. The restricting portion 26 is arranged along the upper end portion Ra of the imaging area R. The restricting portion 26 restricts the subject S from moving to one side (the support portion 22 side) in the X direction. In the present embodiment, the restricting portion 26 extends in the Y direction along the upper end portion Ra of the imaging area R and is installed on the first frame 241 in a state of crossing the opening 25a. As Figure 6 shown, the restricting portion 26 is composed of a rod member 261 and a cushioning member 262. The rod member 261 is a core member installed on the first frame 241. The cushioning member 262 is an elastic member wound around the rod member 261.

[0022] As Figure 2 , Figure 3 , Figure 4 and Figure 5 shown, the apparatus main body 10 further includes an illumination unit 3, an imaging unit 4, and a distance sensor 5. The illumination unit 3, the imaging unit 4, and the distance sensor 5 are arranged on one side (the support portion 22 side) in the X direction with respect to the imaging area R. The housing 250 is on the support portion 22 and houses the illumination unit 3, the imaging unit 4, and the distance sensor 5.

[0023] The illumination unit 3 irradiates the lower body L with excitation light. The illumination unit 3 has a first light emitting area 31 and a second light emitting area 32 arranged in a state of being separated from each other in the Y direction. Each of the first light emitting area 31 and the second light emitting area 32 extends in the Z direction in a state of facing the imaging area R. The first light emitting area 31 and the second light emitting area 32 are arranged such that the closer they are to the imaging area R in the X direction, the farther apart they are from each other in the Y direction. The first light emitting area 31 includes a plurality of first light emitting portions 31a, and the second light emitting area 32 includes a plurality of second light emitting portions 32a. The illumination unit 3 has a function of adjusting the light emitting intensity of each first light emitting portion 31a and the light emitting intensity of each second light emitting portion 32a. Each of the first light emitting portions 31a and the second light emitting portions 32a is composed of, for example, a plurality of LEDs (Light Emitting Diodes) that emit light having a central wavelength of 735 nm. The illumination unit 3 is installed on the second frame 242. That is, the illumination unit 3 is supported by the support portion 22 via the second frame 242.

[0024] The imaging unit 4 detects fluorescence emitted from the lower body L according to the irradiation of the excitation light. The imaging unit 4 faces the imaging area R across the area between the first light emitting area 31 and the second light emitting area 32. The imaging unit 4 is arranged on one side (the side opposite to the imaging area R) in the X direction with respect to the illumination unit 3. That is, the illumination unit 3 is located between the imaging area R and the imaging unit 4 in the X direction. The imaging unit 4 is located at the center of the imaging area R when viewed from the X direction. In the present embodiment, the imaging unit 4 is installed on a rod member 242a that extends upward from the support portion 22 side in the second frame 242. That is, the imaging unit 4 is supported by the support portion 22 via the second frame 242.

[0025] As an example, the imaging unit 4 includes a light detector, a filter disposed in front of the light detector, a lens disposed in front of the filter, and the like. As the light detector, an area sensor (e.g., CCD (Charge Coupled Device), CMOS (Complementary Metal Oxide Semiconductor), etc.) having sensitivity to fluorescence (e.g., light in the near-infrared region) is used. As the filter, an evaporation filter that selectively transmits fluorescence is used. In order to remove the influence of oblique light, the filter may also include an absorption filter. As the lens, a wide-angle lens is used so as to be able to photograph the entire lower body L.

[0026] The distance sensor 5 measures the distance to the lower body L located in the imaging area R. The distance sensor 5 may be, for example, an ultrasonic distance sensor, or an optical distance sensor such as a triangulation method or a ToF (Time of Flight) method. The distance sensor 5 faces the imaging area R across the area between the first light-emitting area 31 and the second light-emitting area 32. The distance sensor 5 is disposed on one side in the X direction (the side opposite to the imaging area R) with respect to the illumination unit 3. When viewed from the X direction, the distance sensor 5 is located at the center of the imaging area R in the Y direction. In the present embodiment, the distance sensor 5 is mounted on a bar 242b, which is a member extending downward from the opposite side of the support portion 22 in the second frame 242. That is, the distance sensor 5 is supported by the support portion 22 via the second frame 242. In addition, based on the distance measured by the distance sensor 5, the light-emitting intensity of the illumination unit 3 may be adjusted so that the intensity of the excitation light irradiated to the lower body L is uniform. The adjustment of the light-emitting intensity of the illumination unit 3 may also be performed based on the intensity of the excitation light detected by another provided light detector.

[0027] As Figure 3 As shown, the apparatus main body 10 includes a camera 6. The camera 6 is mounted on the first frame 241 so as to face the placement portion 21 and not enter the field of view of the imaging unit 4. The camera 6 is accommodated in the placement portion 21 by a housing 250. The space inside the housing 250 becomes a darkroom by a cover 7 that covers the opening 25a in a state where the subject S wears it. Since the camera 6 photographs the feet of the subject S in the space inside the housing 250 that becomes a darkroom, it may be composed of an illumination device and an imaging device, or may be composed of only an imaging device such as an infrared camera. The image obtained by the camera 6 is displayed to the subject S by being displayed on the display unit 12. In addition, the camera 6 may be mounted on the restricting portion 26 or may be mounted on the second frame 242. When the camera 6 is composed of an illumination device and an imaging device, the illumination device may be separated from the imaging device.

[0028] As Figure 5As shown, a positioning portion 8 indicating the standing position of the subject S is provided on the placement portion 21. In the present embodiment, the positioning portion 8 includes a foot shape 81 in a state where the subject S faces the imaging portion 4 side, and a foot shape 82 in a state where the subject S faces the side opposite to the imaging portion 4. Each of the foot shapes 81 and 82 is a mark formed on the placement surface 21a of the placement portion 21. The positioning portion 8 is photographed by the camera 6.

[0029] As Figure 6 shown, a first plate 14 and a scale 15 are mounted on the surface 26a on the imaging portion 4 side of the restricting portion 26. The first plate 14 is a plate for brightness correction. As an example, the first plate 14 is composed of a plurality of members (for example, cloth and acrylic plate) having different intensities of fluorescence emitted according to the irradiation of excitation light. The scale 15 is a member having a scale indicating length. As Figure 7 shown, the second plate 16 is attachable and detachable with respect to the main body portion 2. The second plate 16 is arranged in the main body portion 2 in a state of being in contact with the restricting portion 26 from the side opposite to the imaging portion 4 and being located in the imaging region R. The second plate 16 is a plate for brightness correction, and is, for example, an acrylic plate.

[0030] In the lymphatic system inspection apparatus 1 configured as described above, the control portion 11 is electrically connected to each of the illumination portion 3, the imaging portion 4, the distance sensor 5, the camera 6, the display portion 12, and the input portion 13. The control portion 11 controls the illumination portion 3 so as to emit the excitation light as a flash in accordance with the imaging timing of the imaging portion 4. Thereby, the change in the amount of excitation light irradiated to the lower body L when photographing the lower body L can be suppressed. The control portion 11 generates a fluorescence image of the lower body L based on the fluorescence detected by the imaging portion 4, and controls the display portion 12 so as to display the fluorescence image of the lower body L. The control portion 11 stores the fluorescence image of the lower body L generated by the subject S in the past, and controls the display portion 12 so as to display the fluorescence image of the lower body L generated in the past and the newly generated fluorescence image of the lower body L side by side. In addition, the control portion 11 controls the display portion 12 so as to display the visible light image of the lower body L and the fluorescence image of the lower body L side by side. Furthermore, the control portion 11 can control the display portion 12 so as to magnify a part of at least one image (visible light image, fluorescence image) of the lower body L based on an instruction input to the control portion 11 via the input portion 13.

[0031] In the present embodiment, the control unit 11 controls at least one of the illumination unit 3 and the imaging unit 4 by changing at least one of the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4, thereby generating a plurality of fluorescence images as fluorescence images of the lower body L, and controls the display unit 12 to display the plurality of fluorescence images side by side. That is, in the lymphatic system inspection apparatus 1, a lymphatic system inspection method is implemented, which includes the following steps: controlling at least one of the illumination unit 3 and the imaging unit 4 by changing at least one of the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4 (that is, by changing the exposure amount of the imaging unit 4), thereby generating a plurality of fluorescence images as fluorescence images of the lower body L; and controlling the display unit 12 to display the plurality of fluorescence images side by side.

[0032] In this lymphatic system inspection method, the control unit 11 generates each of the plurality of fluorescence images in a time of 1 second or less (that is, in a time of 1 second or less after an imaging instruction is input to the control unit 11 via the input unit 13). In addition, the change in the exposure amount of the imaging unit 4 can also be implemented by changing at least one of the light emission time of the illumination unit 3, the light emission intensity of the illumination unit 3, the exposure time of the imaging unit 4, the sensor gain of the imaging unit 4, and the lens aperture of the imaging unit 4.

[0033] Figure 8 is a diagram showing a visible light image of an object, Figure 9 is a diagram showing the display unit 12 Figure 8 on which a plurality of fluorescence images I of the object shown are displayed. Figure 8 The object shown is an object in which white paper is wound around an arm model with a phosphor extending in the vertical direction. The white paper covers the phosphor in a state of one layer, two layers, and three layers from top to bottom in sequence. Figure 9 The plurality of fluorescence images I shown are images generated when the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4 are set to 1000 ms, 500 ms, 250 ms, 125 ms, and 62.5 ms. In the one-layer part of the white paper, when the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4 are 500 ms or more, a phosphor much coarser than the actual one is observed due to fluorescence scattering. In the two-layer part of the white paper, when the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4 are 125 ms or more, the phosphor can be visually observed. In the three-layer part of the white paper, when the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4 are 500 ms or more, the phosphor can be visually observed. As can be seen from the above, by adjusting at least one of the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4, the state of the lymphatic system of the lower body L can be appropriately grasped.

[0034] As described above, in the lymphatic system inspection device 1, each of the first light-emitting region 31 and the second light-emitting region 32 of the illumination unit 3 extends in the Z direction in a state facing the imaging region R, and the imaging unit 4 faces the imaging region R across the region between the first light-emitting region 31 and the second light-emitting region 32. Thereby, the lower body L of the subject S located in the imaging region R can be uniformly irradiated with excitation light, and fluorescence emitted from the lower body L according to the irradiation of the uniform excitation light can be detected. Thereby, according to the lymphatic system inspection device 1, a fluorescence image of the lower body L suitable for inspecting the lymphatic system of the lower body L of the subject S can be obtained.

[0035] In the lymphatic system inspection device 1, when viewed from the X direction, the imaging unit 4 is located at the center of the imaging region R. Thereby, deformation in the obtained fluorescence image can be suppressed.

[0036] In the lymphatic system inspection device 1, in the X direction, the illumination unit 3 is located between the imaging region R and the imaging unit 4. Thereby, the lower body L of the subject S located in the imaging region R can be irradiated with excitation light more uniformly.

[0037] In the lymphatic system inspection device 1, the illumination unit 3 has a function of adjusting the light emission intensity of each of the first light-emitting portions 31a and the light emission intensity of each of the second light-emitting portions 32a. Thereby, according to the shape of the lower body L of the subject S located in the imaging region R, etc., the lower body L can be uniformly irradiated with excitation light.

[0038] In the lymphatic system inspection device 1, the first light-emitting region 31 and the second light-emitting region 32 are arranged such that they are farther apart from each other in the Y direction as they are closer to the imaging region R in the X direction. Thereby, the lower body L of the subject S located in the imaging region R can be irradiated with excitation light more uniformly.

[0039] In addition, in the lymphatic system inspection device 1, for the imaging region R where the lower body L of the subject S is located, the illumination unit 3 and the imaging unit 4 are arranged on one side in the X direction, and the movement of the subject S in the X direction is restricted by a restricting unit 26 arranged along the upper end portion Ra of the imaging region R. Thereby, the distance between the illumination unit 3 and the lower body L of the subject S and the distance between the imaging unit 4 and the lower body L of the subject S can be maintained constant, and shaking of the lower body L of the subject S can be suppressed. Thereby, according to the lymphatic system inspection device 1, a fluorescence image of the lower body L suitable for inspecting the lymphatic system of the lower body L of the subject S can be obtained.

[0040] In the lymphatic system inspection device 1, the restricting unit 26 extends in the Y direction, and the first plate 14 for brightness correction is arranged on the surface 26a on the imaging unit 4 side of the restricting unit 26. Thereby, the brightness of the fluorescence image can be adjusted for each obtained fluorescence image.

[0041] In the lymphatic system inspection device 1, the restricting portion 26 extends in the Y direction, and the scale 15 is disposed on the surface 26a on the side of the imaging unit 4 of the restricting portion 26. Thus, the dimensions of each part of the lower body L can be grasped from the acquired fluorescence image.

[0042] In the lymphatic system inspection device 1, the second plate 16 for brightness correction is disposed in the main body portion 2 in such a manner that it is in contact with the restricting portion 26 from the side opposite to the imaging unit 4 and is located in the imaging region R. Thus, the brightness of the fluorescence image can be adjusted for each lymphatic system inspection device 1.

[0043] In the lymphatic system inspection device 1, a distance sensor 5 is disposed on one side in the X direction with respect to the imaging region R. Thus, the position of the lower body L of the subject S in the X direction can be accurately grasped.

[0044] In addition, in the lymphatic system inspection device 1 (and the above-described lymphatic system inspection method), by changing at least one of the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4, a plurality of fluorescence images are generated as the fluorescence images of the lower body L of the subject S, and the plurality of fluorescence images are displayed side by side. Although the intensity of the fluorescence changes according to the state of the lymphatic system of the lower body L, the state of the lymphatic system of the lower body L can be appropriately grasped by the plurality of fluorescence images that can be generated and displayed as described above. Thus, according to the lymphatic system inspection device 1 (and the above-described lymphatic system inspection method), the inspection of the lymphatic system of the lower body L of the subject S can be appropriately performed.

[0045] In the lymphatic system inspection device 1, the control unit 11 generates each of the plurality of fluorescence images in a time of 1 second or less. Thus, a plurality of fluorescence images can be acquired while suppressing the shaking of the lower body L of the subject S.

[0046] In the lymphatic system inspection device 1, the control unit 11 controls the illumination unit 3 in such a manner that the excitation light is emitted as a flash. Thus, the change in the amount of excitation light irradiated to the lower body L of the subject S can be suppressed, and a plurality of fluorescence images can be acquired.

[0047] In the lymphatic system inspection device 1, the control unit 11 stores the fluorescence images of the lower body L generated by the subject S in the past, and controls the display unit 12 in such a manner that the fluorescence images of the lower body L generated in the past and the newly generated fluorescence images of the lower body L are displayed side by side. Thus, the temporal change in the state of the lymphatic system of the lower body L of the subject S can be appropriately grasped.

[0048] In addition, in the lymphatic system inspection device 1, a positioning portion 8 indicating the standing position of the subject S is provided on the placement portion 21 where the subject S stands. Thereby, the distances between the illumination unit 3 and the lower body L of the subject S and between the imaging unit 4 and the lower body L of the subject S can be maintained constant, and the orientations of the feet of the subject S with respect to the illumination unit 3 and the imaging unit 4 can be made to coincide with a specified orientation. Accordingly, with the lymphatic system inspection device 1, an appropriate fluorescence image of the lower body L for inspecting the lymphatic system of the lower body L of the subject S can be obtained.

[0049] In the lymphatic system inspection device 1, the positioning portion 8 includes a foot shape 81 when the subject S faces the imaging unit 4 side and a foot shape 82 when the subject S faces the side opposite to the imaging unit 4. Thereby, in each of the states where the subject S faces the imaging unit 4 side and where the subject S faces the side opposite to the imaging unit 4, the orientations of the feet of the subject S with respect to the illumination unit 3 and the imaging unit 4 can be made to coincide with a specified orientation.

[0050] In the lymphatic system inspection device 1, a wall portion 25 forms a frame body 250 that divides the imaging region R and houses the illumination unit 3 and the imaging unit 4, and an opening 25a for disposing the subject S inside is formed in the wall portion 25. Thereby, the influence of interfering light can be suppressed and a fluorescence image of the lower body L of the subject S can be obtained.

[0051] In the lymphatic system inspection device 1, a cover 7 worn by the subject S covers the opening 25a. Thereby, the influence of interfering light can be more reliably suppressed and a fluorescence image of the lower body L of the subject S can be obtained.

[0052] In the lymphatic system inspection device 1, the support portion 22 and the second wall portion 252 can be attached to and detached from the placement portion 21 and the first wall portion 251. Thereby, the portability of the lymphatic system inspection device 1 can be improved.

[0053] In the lymphatic system inspection device 1, the positioning portion 8 is photographed by the camera 6. Thereby, even when the subject S cannot directly visually observe the positioning portion 8, the subject S can visually observe the image obtained by the camera 6 and make the standing position coincide with the positioning portion 8.

[0054] The present disclosure is not limited to the above-described embodiments. For example, as Figure 10 shown, the restricting portion 26 and the imaging unit 4 (refer to Figure 3)The surface 26b on the opposite side may also be a curved surface that bends in a manner along the lower abdomen of the subject S (i.e., in a manner that is recessed toward the imaging unit 4 side). In addition, the positioning unit 8 may be provided in the concave or convex portion of the placement surface 21a in place of the foot shapes 81, 82, or together with the foot shapes 81, 82 in a manner that matches the foot shape of the subject S. In addition, at least one of the illumination unit 3, the imaging unit 4, the distance sensor 5, the camera 6, and the restricting unit 26 may be mounted on the frame 24 in a manner that allows at least one of position adjustment and angle adjustment. Symbol Explanation

[0055] 1…Lymphatic system examination device, 2…Main body, 3…Illumination unit, 4…Imaging unit, 5…Distance sensor, 6…Camera, 7…Cover, 8…Positioning unit, 11…Control unit, 12…Display unit, 14…First plate, 15…Measuring scale, 16…Second plate, 21…Placement unit, 22…Support unit, 25…Wall portion, 25a…Opening, 26…Restricting unit, 26a…Surface, 31…First light emitting area, 31a…First light emitting part, 32…Second light emitting area, 32a…Second light emitting part, 81, 82…Foot shapes, 250…Frame body, 251…First wall portion, 252…Second wall portion, L…Lower body, R…Imaging area, Ra…Upper end portion, S…Subject.

Claims

1. A lymphatic system examination device, wherein, it includes: a main body portion having a placement portion on which a subject injected with a fluorescent dye in the lymphatic system stands, and a imaging area on the placement portion where the lower body of the subject is located; an illumination portion that irradiates excitation light onto the lower body; and an imaging portion that detects fluorescence emitted from the lower body according to the irradiation of the excitation light, and a positioning portion indicating the standing position of the subject is provided on the placement portion.

2. The lymphatic system examination device according to claim 1, wherein, the positioning portion includes: the foot shape when the subject faces the imaging portion side; and the foot shape when the subject faces the side opposite to the imaging portion.

3. The lymphatic system examination device according to claim 1 or 2, wherein, the main body portion further has: a support portion that supports the illumination portion and the imaging portion; and a wall portion that forms a frame dividing the imaging area and accommodating the illumination portion and the imaging portion, and an opening for arranging the subject inside is formed in the wall portion.

4. The lymphatic system examination device according to claim 3, wherein, it further includes: a cover that covers the opening in a state of being worn by the subject.

5. The lymphatic system examination device according to claim 3 or 4, wherein, the wall portion includes: a first wall portion installed on the placement portion; and a second wall portion installed on the support portion, and the support portion and the second wall portion can be detached and attached relative to the placement portion and the first wall portion.

6. The lymphatic system examination device according to any one of claims 3 to 5, wherein, it further includes: a camera that photographs the positioning portion.

Citation Information

Patent Citations

  • Method for evaluating function of lymphatic system

    JP2019118803A