Diaphragm one-way valve type bacteria-proof filter for dropper and air permeability comparison test method

Abstract

The present invention discloses a diaphragm one-way valve type antibacterial filter for a dropper and its air permeability comparison test method, comprising: an antibacterial filter membrane, a T-shaped rubber ring injection-molded on the outer side of the antibacterial filter membrane, an air hole axially arranged in the T-shaped rubber ring and penetrating the T-shaped rubber ring, the antibacterial filter membrane is horizontally placed in the large diameter end of the T-shaped rubber ring and blocks the air hole, a mounting groove extending downwardly from the T-shaped rubber ring is provided, a one-way diaphragm is provided in the mounting groove, the one-way diaphragm comprises: an integrally formed positioning ring, an elastic sealing piece and an elastic connecting wire, the positioning ring is clamped in the mounting groove, the elastic sealing piece is zero-pressure-fitted on the bottom wall of the T-shaped rubber ring and blocks the air hole, and the elastic connecting wire is evenly distributed circumferentially between the positioning ring and the elastic sealing piece. The advantage of the present invention is that it can prevent the antibacterial filter membrane from contacting the liquid in the dropper bottle, so that the membrane pores in the antibacterial filter membrane will not be blocked, the hydrophobicity of the antibacterial filter membrane will not be destroyed, and the complete hydrophobicity and air permeability are maintained.

Description

Technical Field

[0001] The present invention relates to the field of medical packaging, in particular to a diaphragm one-way valve type bacteria-blocking filter for a dropper and an air permeability comparison test method. Background Art

[0002] In daily life, we need to use dropper bottles for precise drug delivery, and the most common one is the eye dropper bottle. The dropper bottles currently on the market have the problem that the liquid medicine is contaminated by the air and flows back into the bottle after the dropper is completed, and the liquid medicine remains on the dropper head. In response to these problems, an air-blocking sterile dropper bottle with the authorization number CN118415813B that can handle the residual liquid externally has appeared on the market. After the dropper is completed, under the action of negative pressure, the residual liquid medicine will be mixed with air and enter the isolation groove of the valve body. The residual liquid medicine and air will be separated after entering the isolation groove, and the residual liquid medicine will flow in the isolation groove, while the air will flow back into the bottle body through the sterilization filter element in the return air hole to make the bottle body expand and recover. In this way, the residual liquid medicine will not be blocked on the sterilization filter element and affect the reflux effect. However, during actual use, it was found that after the drug solution came into contact with the sterilizing filter membrane, the drug solution would remain on the sterilizing filter membrane. The drug solution remaining on the membrane pores would precipitate crystals and block the membrane pores, resulting in increased filtration resistance of the sterilizing filter membrane, affecting air reflux, and the bottle body could not be restored in time. Moreover, the biological components in the drug solution (such as hyaluronic acid) would form a hydrophilic contamination layer on the surface of the sterilizing filter membrane, covering the mesh gap structure of the original sterilizing filter membrane, thereby destroying the air passage efficiency of the sterilizing filter membrane. When dripping, the sterilizing filter membrane would not have good air permeability, and the bottle body could not be restored, resulting in functional failure when used again. Summary of the Invention

[0003] The present invention aims to provide a membrane one-way valve type bacteria-blocking filter for a dropper, which can prevent a liquid medicine from contacting a bacteria-blocking filter membrane and does not hinder air backflow, and a comparative test method for its air permeability.

[0004] To achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a diaphragm one-way valve type bacteria-blocking filter for a dropper, comprising: a hydrophobic bacteria-blocking filter membrane, a T-shaped rubber ring injection-molded and compounded on the outer side of the bacteria-blocking filter membrane, an air hole penetrating the T-shaped rubber ring axially arranged in the T-shaped rubber ring, the bacteria-blocking filter membrane is horizontally placed in the large-diameter end of the T-shaped rubber ring and blocks the air hole, a mounting groove is extended downwardly on the T-shaped rubber ring, a one-way diaphragm is arranged in the mounting groove, the one-way diaphragm comprises: an integrally formed positioning ring, an elastic sealing piece and an elastic connecting wire, the positioning ring is clamped in the mounting The groove provides rigid support for the one-way diaphragm, and the elastic sealing piece fits on the bottom wall of the T-shaped rubber ring with zero pressure and blocks the air hole, which is used to control the opening and closing of the air hole. The elastic sealing piece and the positioning ring are coaxially arranged, and the elastic connecting wire is evenly distributed between the positioning ring and the elastic sealing piece. When the air flow blows on the elastic sealing piece, the elastic connecting wire controls the directional opening of the elastic sealing piece through elastic deformation. When no air hole is blown on the elastic sealing piece, the elastic connecting wire controls the directional closing of the elastic sealing piece through elastic deformation, so that the elastic sealing piece and the T-shaped rubber ring fit together again.

[0005] Furthermore, the aforementioned dropper uses a diaphragm one-way valve type antibacterial filter, wherein the elastic connecting wire is arc-shaped, and the two ends of the elastic connecting wire are respectively arranged on the inner wall of the positioning ring and the outer wall of the elastic sealing piece, and the center of the elastic connecting wire is concentric with the center of the elastic sealing piece.

[0006] Furthermore, the aforementioned dropper uses a diaphragm one-way valve type antibacterial filter, wherein the antibacterial filter membrane is made of PTFE material, the filtration accuracy of the antibacterial filter membrane is 0.2μm, the one-way diaphragm is injection molded by TPE material, the diameter of the elastic sealing piece in the one-way diaphragm is 2~3mm, the upper and lower thicknesses of the elastic connecting wire and the left and right widths of the arc segment are the same, both of which are 0.18~0.22mm, the arc length of the elastic connecting wire is 1.2~1.25mm, and the central angle is 45°.

[0007] Furthermore, the aforementioned dropper uses a diaphragm one-way valve type antibacterial filter, wherein an annular groove is provided on the bottom wall of the T-shaped rubber ring, and a positioning convex ring is provided on the top wall of the elastic sealing piece. When the elastic sealing piece is attached to the T-shaped rubber ring at zero pressure, the positioning convex ring is inserted into the annular groove.

[0008] Furthermore, the aforementioned dropper uses a diaphragm one-way valve type antibacterial filter, wherein the bottom wall of the elastic sealing piece is a protruding arched pressure wall, the arched pressure wall is coaxial with the elastic sealing piece, the maximum diameter of the arched pressure wall is larger than the diameter of the pore, and a trumpet-shaped buffer groove is recessed at the center position of the top wall of the elastic sealing piece, and the maximum diameter of the trumpet-shaped buffer groove is smaller than the aperture of the pore.

[0009] Furthermore, in the aforementioned diaphragm one-way valve type bacteria-blocking filter for the dropper, a weight-reducing process groove is provided at the apex of the arched pressure-bearing wall.

[0010] Furthermore, the aforementioned dropper uses a diaphragm one-way valve type antibacterial filter, in which a shifting ring is protruding on the inner wall of the mounting groove. When the positioning ring is clamped in the mounting groove, the outer wall of the positioning ring rests on the inner wall of the mounting groove, the top wall of the positioning ring rests on the bottom wall of the T-shaped rubber ring, and the bottom wall of the positioning ring rests on the shifting ring.

[0011] The air permeability comparison test method described above uses a bacteria-blocking filter without a one-way diaphragm and the above-mentioned dropper-use diaphragm one-way valve-type bacteria-blocking filter, and the steps are as follows:

[0012] S1. Assemble the test device and connect the oil-water separator, pressure reducing valve, fine-tuning valve, gas flow sensor, intelligent digital pressure gauge and mounting head in sequence through the air pipe. The oil-water separator is connected to the compressed air source through the air pipe.

[0013] S2. Calibrate the test device. Connect the mounting head directly to the external environment. Then, turn on the compressed air source. The compressed air will remain dry after passing through the oil-water separator. The flow rate of the compressed air in the air pipe will be kept constant through the regulation of the pressure reducing valve and the fine-tuning valve. The gas flow sensor will show a constant airflow of 0 ml / min. The gas will be discharged directly from the mounting head into the air. The pressure value displayed on the intelligent digital pressure gauge is 0 kPa.

[0014] S3. Calibrate the bacteria-repelling filter. Maintaining the gas flow rate in S2, install multiple bacteria-repelling filters without one-way diaphragms on the mounting head in sequence. Observe and record the gas flow rate in the gas flow sensor and the pressure value in the intelligent digital pressure gauge. Then, select the bacteria-repelling filters with the same gas flow rate and pressure value.

[0015] S4. Classify the bacteria-repelling filters and prepare the injection solution. Divide the bacteria-repelling filters selected in S3 into five groups. The bacteria-repelling filters in the first group are not treated and are kept dry. The bacteria-repelling filters in the second group are in contact with the injection solution for 12 hours. The bacteria-repelling filters in the third group are in contact with the injection solution for 48 hours. The bacteria-repelling filters in the fourth group are in contact with the injection solution for 72 hours. The bacteria-repelling filters in the fifth group are provided with a one-way membrane and are then in contact with the injection solution for 72 hours. When the bacteria-repelling filters are in contact with the injection solution, their bottoms are immersed in the injection solution, and the injection solution does not overflow from the top of the T-shaped rubber ring onto the bacteria-repelling filter membrane.

[0016] S5. Start the test. Turn on the compressed air source in S1 and adjust the gas flow rate to the same gas flow rate Qml / min as in S2. At this time, the pressure value on the intelligent digital pressure gauge is 0kPa. Install the antibacterial filter in the first group on the mounting head, and obtain a gas flow rate of Q1ml / min and a pressure value of F1kPa. Install the antibacterial filter in the second group on the mounting head, and obtain a gas flow rate of Q2ml / min and a pressure value of F2kPa. Install the antibacterial filter in the third group on the mounting head, and obtain a gas flow rate of Q3ml / min and a pressure value of F3kPa. Install the antibacterial filter in the fourth group on the mounting head, and obtain a gas flow rate of Q4ml / min and a pressure value of F4kPa. Install the antibacterial filter in the fifth group on the mounting head, and obtain a gas flow rate of Q5ml / min and a pressure value of F5kPa.

[0017] S6. Comparison results: First, the first to fourth groups of bacteria-blocking filters were compared, and the following results were obtained: flow rate: Q1>Q2>Q3>Q4, pressure value: F1<F2<F3<F4, indicating that the longer the contact time between the bacteria-blocking filter membrane and the injection liquid, the greater the resistance of the bacteria-blocking filter membrane and the smaller the gas flow rate; then the fifth group of bacteria-blocking filters was compared with the first and fourth groups of bacteria-blocking filters, and the following results were obtained: flow rate: Q5=Q1>Q4, pressure value: F5>F1<F4, indicating that after setting the one-way diaphragm, the resistance will increase when the one-way diaphragm is opened, but the gas flow rate will not be reduced. This shows that when the bacteria-blocking filter equipped with a one-way diaphragm comes into contact with the injection liquid, the one-way diaphragm can effectively prevent the injection liquid from contacting the bacteria-blocking filter membrane, so that the bacteria-blocking filter membrane remains dry.

[0018] Further, the aforementioned air permeability comparison test method, wherein the mounting head includes: a rod body, a vent hole penetrating the rod body is provided in the rod body, a tracheal hole connected to the vent hole is provided at the upper end of the rod body, the trachea in the test device is inserted into the tracheal hole and sealed with the tracheal hole, the small diameter end of the T-shaped rubber ring in the antibacterial filter is sealed and clamped in the vent hole, and the lower end wall of the rod body is sealed and fitted on the upper top wall of the large diameter end of the T-shaped rubber ring; in S4, the antibacterial filter that needs to be in contact with the injection liquid is installed on the mounting head, and then comes into contact with the injection liquid.

[0019] Furthermore, in the aforementioned air permeability comparison test method, the injection solution in S4 is a 0.9% NaCl injection solution.

[0020] The advantages of the present invention are that the pores can be blocked by the one-way diaphragm, thereby protecting the antibacterial filter membrane located in the pores from contacting the liquid medicine in the dropper bottle. In this way, the membrane pores in the antibacterial filter membrane will not be blocked, and the hydrophobicity of the antibacterial filter membrane will not be destroyed, thereby maintaining complete hydrophobicity and air permeability; and there is zero pressure fit between the elastic sealing piece in the one-way diaphragm and the T-shaped rubber ring. The pressure generated when the gas refluxes can push open the elastic sealing piece in the one-way diaphragm, thereby refluxing into the bottle body, without affecting the gas reflux efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a structural schematic diagram of the diaphragm one-way valve type bacteria-blocking filter for the dropper of the present invention.

[0022] Figure 2 yes Figure 1 Schematic diagram of the cross-sectional structure when the elastic sealing piece in the one-way diaphragm is fitted with the T-shaped rubber ring.

[0023] Figure 3 yes Figure 1 Schematic diagram of the cross-sectional structure when the elastic sealing piece and T-shaped rubber ring in the one-way diaphragm are separated.

[0024] Figure 4 yes Figure 2 Schematic diagram of the three-dimensional structure of the one-way diaphragm.

[0025] Figure 5 yes Figure 2 Schematic diagram of the three-dimensional structure of the one-way diaphragm in the other direction.

[0026] Figure 6 It is a structural schematic diagram of the testing device used in the air permeability comparison test method described in the present invention.

[0027] Figure 7 yes Figure 6 Schematic diagram of the structure of the mounting head.

[0028] Figure 8 It is the static stress analysis diagram of the one-way diaphragm. DETAILED DESCRIPTION

[0029] The technical solution of the present invention will be further described below with reference to the accompanying drawings and preferred embodiments.

[0030] like Figures 1 to 5As shown, the diaphragm one-way valve type bacteria-blocking filter for a dropper of the present invention comprises: a hydrophobic bacteria-blocking filter membrane 1, the bacteria-blocking filter membrane 1 being made of PTFE material, the filtration accuracy of the bacteria-blocking filter membrane 1 being 0.2 μm, a T-shaped rubber ring 2 being injection-molded and compounded on the outer side of the bacteria-blocking filter membrane 1, an air hole 21 penetrating the T-shaped rubber ring 2 being axially arranged in the T-shaped rubber ring 2, the bacteria-blocking filter membrane 1 being horizontally placed in the large diameter end of the T-shaped rubber ring 2 and blocking the air hole 21, in this embodiment, six through holes 24 are evenly distributed circumferentially on the T-shaped rubber ring 2, and the bacteria-blocking filter membrane 1 is also horizontally placed in these six through holes 24, the molding method between the T-shaped rubber ring 2 and the bacteria-blocking filter membrane 1 can refer to the continuous molding production line and molding process of the sterilizing filter membrane assembly in the dropper with the authorization number: CN117140848B, these six through holes The hole 24 is only for auxiliary purposes. When the bacteria-blocking filter is installed in the dropper, the valve body in the dropper will block the six through holes 24 in the bacteria-blocking filter, leaving only the air hole 21 for reflux. Moreover, since the T-shaped rubber ring 2 is injection-molded on the bacteria-blocking filter membrane 1, during the injection molding process, the T-shaped rubber ring 2 will separate the bacteria-blocking filter membrane 1 in the air hole 21 from the bacteria-blocking filter membrane 1 in the through hole 24. In other words, the bacteria-blocking filter membrane 1 in the through hole 24 is not connected to the bacteria-blocking filter membrane 1 in the air hole 21. After the bacteria-blocking filter membrane 1 in the through hole 24 contacts the medicinal solution, the medicinal solution will not spread to the bacteria-blocking filter membrane 1 in the air hole 21. The connection structure between the bacteria-blocking filter and the valve body can refer to the authorization number: CN118415813B, a gas-blocking sterile dropping bottle with external treatment of residual liquid.

[0031] A mounting groove 22 is provided on the T-shaped rubber ring 2, and a shift ring 221 is provided on the inner side wall of the mounting groove 22. A one-way diaphragm 3 is provided in the mounting groove 22. The one-way diaphragm 3 is made of TPE material by injection molding. The one-way diaphragm 3 includes: an integrally formed positioning ring 31, an elastic blocking piece 32 and an elastic connecting wire 33. The positioning ring 31 is provided in the mounting groove 22 to provide rigid support for the one-way diaphragm 3. The outer side wall of the positioning ring 31 is against the inner side wall of the mounting groove 22, and the top wall of the positioning ring 31 is provided. The bottom wall of the T-shaped rubber ring 2 is against the bottom wall of the positioning ring 31, and the bottom wall of the positioning ring 31 is against the gear ring 221, which limits the positioning ring 31. The elastic sealing piece 32 is coaxially arranged with the positioning ring 31. The elastic sealing piece 32 is zero-pressure fitted on the bottom wall of the T-shaped rubber ring 2 and blocks the air hole 21, which is used to control the switch of the air hole 21. The elastic sealing piece 32 and the T-shaped rubber ring 2 can be close to each other under the elastic support of the elastic connecting wire 33 to achieve zero-pressure fitting. An annular groove is provided on the bottom wall of the T-shaped rubber ring 2 23, a positioning convex ring 321 is provided on the top wall of the elastic sealing piece 32. When the elastic sealing piece 32 is fitted on the T-shaped rubber ring 2 at zero pressure, the positioning convex ring 321 is snapped into the annular groove 23, thereby improving the fitting stability and sealing performance between the elastic sealing piece 32 and the T-shaped rubber ring 2. The bottom wall of the elastic sealing piece 32 is a protruding arched pressure wall 322. The arched pressure wall 322 is coaxial with the elastic sealing piece 32. The maximum diameter of the arched pressure wall 322 is larger than the aperture of the pore 21. A weight-reducing process groove 323 is provided at the top point of 22 to prevent the one-way diaphragm 3 from excessively extending and unsightly after being installed in the mounting groove 22 of the T-shaped rubber ring 2. A trumpet-shaped buffer groove 324 is recessed at the center position of the top wall of the elastic sealing piece 32. The maximum diameter of the trumpet-shaped buffer groove 324 is smaller than the aperture of the pore 21. When the elastic sealing piece 32 is pushed open and deformed by the airflow, the trumpet-shaped buffer groove 324 provides deformation space for the elastic sealing piece 32 by being recessed or expanded, thereby reducing the deformation fatigue of the elastic sealing piece 32. The elastic connecting wire 33 is evenly distributed around the circumference between the positioning ring 31 and the elastic sealing piece 32. When the airflow passes through the air hole 21 and blows on the elastic sealing piece 32, the elastic connecting wire 33 controls the elastic sealing piece 32 to open in a directional manner through elastic deformation. When no airflow passes through the air hole 21 and blows on the elastic sealing piece 32, the elastic connecting wire 33 controls the elastic sealing piece 32 to close in a directional manner through elastic deformation, so that the elastic sealing piece 32 and the T-shaped rubber ring 2 are re-fitted.

[0032] The elastic connecting wire 33 is arc-shaped, and the two ends of the elastic connecting wire 33 are respectively arranged on the inner wall of the positioning ring 31 and the outer wall of the elastic sealing piece 32. The center of the elastic connecting wire 33 is concentric with the center of the elastic sealing piece 32. The elastic connecting wire 33 is arranged concentric with the elastic sealing piece 32 so that each bending arc of the elastic connecting wire 33 is the same, and the elastic restoring force is evenly distributed, so that the valve opening pressure of the elastic sealing piece 32 is more stable and there will be no jamming. Moreover, when closing the valve, the concentrically arranged arc-shaped elastic connecting wire 33 can evenly pull the elastic sealing piece 32, so that the elastic sealing piece 32 is automatically centered, avoiding reset offset and poor sealing. Since the elastic connecting wires 33 evenly distributed around the circumference are all arc-shaped, there are arc-shaped gaps evenly distributed around the circumference between the elastic sealing piece 32 and the positioning ring 31. When the airflow in the air hole 21 pushes open the elastic sealing piece 32 and flows outward, the airflow will flow along the circumference under the guidance of the arc-shaped gaps, reducing gas turbulence and pressure loss and increasing the airflow velocity.

[0033] After the membrane one-way valve type antibacterial filter described in the present application is installed in the dropper, the one-way diaphragm 3 blocks the air hole 21, and the liquid medicine in the bottle cannot contact the antibacterial filter membrane 1 in the air hole 21, and the antibacterial filter membrane 1 in the air hole 21 can be kept dry. When dripping, the pressure of the liquid medicine will be applied to the elastic blocking piece 32. If there is no arched pressure wall 322, the force exerted on the elastic blocking piece 32 is uneven, and it is easy to have a situation where the pressure on one side is large and the pressure on the other side is small. The elastic blocking piece 32 is prone to warping, resulting in the liquid medicine It contacts the antibacterial filter membrane 1 in the pore 21. When an arched pressure-bearing wall 322 is set on the elastic sealing piece 32, the arched pressure-bearing wall 322 will evenly distribute the pressure to the entire elastic sealing piece 32, so that the elastic sealing piece 32 is evenly compressed. Since the maximum diameter of the arched pressure-bearing wall 322 is larger than the aperture of the pore 21, the force of the arched pressure-bearing wall 322 in evenly dispersing the pressure can act on the elastic sealing piece 32 on the outside of the pore 21 that is in contact with the T-shaped rubber ring 2, ensuring the sealing performance of the elastic sealing piece 32 on the pore 21. When the dripping is completed, the backflowing air is separated from the residual liquid and then sprayed onto the elastic sealing piece 32 through the pore 21. Since there is zero pressure between the elastic sealing piece 32 and the T-shaped rubber ring 2, the elastic sealing piece 32 will open after being sprayed by the backflowing air, thereby entering the bottle body. Since the elastic sealing piece 32 in the one-way diaphragm 3 blocks the pore 21, the antibacterial filter 1 in the pore 21 will not come into contact with the liquid medicine and be blocked, which will not affect the gas reflux efficiency. When the dropper bottle is inverted to return air, the reflux gas is evenly discharged from all sides of the elastic sealing piece 32, not only pushing away the liquid medicine around the elastic sealing piece 32, but also forming annular bubbles around the elastic sealing piece 32. When there is no airflow in the pore 21 to push the elastic sealing piece 32, the elastic sealing piece 32 will reattach to the T-shaped rubber ring 2 to seal the pore 21. The annular bubbles will not rupture until the elastic sealing piece 32 is attached to the T-shaped rubber ring 2, thus preventing the liquid medicine from entering the pore 21 through the opened elastic sealing piece 32 and contacting the antibacterial filter 1 in the pore 21.

[0034] In this embodiment, the antibacterial filter membrane 1 is a PTFE filter membrane (TE type) produced by Sterling, an independent operating company under the Danaher Group. The filtration accuracy of the antibacterial filter membrane 1 in this embodiment is 0.2μm, and the bubble point of this type of antibacterial filter membrane 1 is 1.29psi, which means that the air flow pressure needs to be greater than 1.29psi to pass through the antibacterial filter membrane 1 and flow back into the bottle body. For the characteristics of the antibacterial filter membrane 1, please refer to the "Whatman" provided by Sterling. TM Laboratory Filtration and Separation Product Guide.

[0035] In this embodiment, the one-way diaphragm 3 is injection molded from TPE material. The diameter of the elastic sealing piece 32 in the one-way diaphragm 3 is 2 to 3 mm, preferably 2.5 mm. The upper and lower thicknesses of the elastic connecting wire 33 and the left and right widths of the arc segment are the same, both of which are 0.18 to 0.22 mm, preferably 0.2 mm. The arc length of the elastic connecting wire 33 is 1.2 to 1.25 mm, preferably 1.24 mm, and the central angle is 45°.

[0036] Such as Figure 8 As shown, after performing static stress analysis on the one-way diaphragm 3 using finite element analysis software, it can be seen that under a pressure of 1 psi, the displacement gap generated by the elastic sealing piece 32 in the one-way diaphragm 3 is 0.003566 mm, that is, 3.566 μm. In other words, under a pressure of 1 psi, the elastic connecting wire 33 in the one-way diaphragm 3 can undergo elastic deformation, and the return air in the pore 21 can pass through the antibacterial filter membrane 1 with a filtration accuracy of 0.2 μm. Therefore, the air returning from the pore 21 can push open the elastic sealing piece 32 and pass through the gap between the opened elastic sealing piece 32 and the T-shaped rubber ring 2. In the reflux bottle, this is because the bubbling point of the antibacterial filter membrane 1 is 1.29 psi, and the pressure of the reflux air in the pore 21 when passing through the antibacterial filter membrane 1 is greater than 1.29 psi. Therefore, after passing through the antibacterial filter membrane 1, the reflux air can push the elastic sealing piece 32 to elastically deform the elastic connecting wire 33, thereby opening the elastic sealing piece 32. The membrane pore diameter of the antibacterial filter membrane 1 is 0.2 μm, which is much smaller than the displacement gap of the elastic sealing piece 32 of 3.566 μm. Therefore, the air can pass through the antibacterial filter membrane 1 and reflux into the bottle through the gap between the elastic sealing piece 32 and the T-shaped rubber ring 2. When selecting a bacteria-blocking filter membrane 1 with other filtration accuracies, a static stress analysis of the one-way diaphragm 3 is performed based on the bubbling point of the bacteria-blocking filter membrane 1 using finite element analysis software to obtain the pressure required for the elastic blocking piece 32 and the elastic connecting wire 33 in the one-way diaphragm 3 to elastically deform at the corresponding bubble point of the bacteria-blocking filter membrane 1. Then, the parameters of the elastic blocking piece 32 and the elastic connecting wire 33 in the one-way diaphragm 3 are corrected based on the pressure. After the correction is completed, a one-way diaphragm 3 that is compatible with the bacteria-blocking filter membrane 1 with the filtration accuracies can be produced.

[0037] During the production process, in order to test the effect of the antibacterial filter with the one-way membrane 3, an air permeability comparison test is required. The steps are as follows:

[0038] S1. Assemble the test device and connect the oil-water separator 4, pressure reducing valve 5, fine-tuning valve 6, gas flow sensor 7, intelligent digital pressure gauge 8 and mounting head 9 in sequence through the air pipe. The oil-water separator 4 is connected to the compressed air source 10 through the air pipe. Figure 6 、 Figure 7 As shown;

[0039] S2. Calibrate the test device. Connect the mounting head 9 directly to the external environment. Then, open the compressed air source 10. The compressed air is kept dry after passing through the oil-water separator 4. The flow rate of the compressed air in the trachea is maintained constant by regulating the pressure reducing valve 5 and the fine-tuning valve 6. The gas flow sensor 7 shows a constant airflow of 0 ml / min. In this embodiment, the gas flow rate displayed by the gas flow sensor 7 is 70 ml / min. The gas is directly discharged from the mounting head 9 into the air. The pressure value displayed on the intelligent digital pressure gauge 8 is 0 kPa, indicating that the trachea is unobstructed and there are no obstacles hindering the gas flow.

[0040] S3. Calibrate the bacteria-repelling filter. Maintaining the gas flow rate in S2, install multiple bacteria-repelling filters without one-way diaphragms 3 on the mounting head 9 in sequence. Observe and record the gas flow rate from the gas flow sensor 7 and the pressure value from the intelligent digital pressure gauge 8. Then, select the bacteria-repelling filters with the same gas flow rate and pressure value. In this step, the gas flow rate when passing through the bacteria-repelling filter without one-way diaphragms 3 is 48 ml / min and the pressure value is 11.8 kPa.

[0041] S4. Classify the bacteria-repelling filters and prepare 0.9% NaCl injection solution. Divide the bacteria-repelling filters selected in S3 into five groups. The bacteria-repelling filters in the first group are not treated and are kept dry. The bacteria-repelling filters in the second group are in contact with the injection solution for 12 hours. The bacteria-repelling filters in the third group are in contact with the injection solution for 48 hours. The bacteria-repelling filters in the fourth group are in contact with the injection solution for 72 hours. The bacteria-repelling filters in the fifth group are provided with a one-way membrane 3 and are then in contact with the injection solution for 72 hours. When the bacteria-repelling filters are in contact with the injection solution, their bottoms are immersed in the injection solution, and the injection solution does not overflow from the top of the T-shaped rubber ring 2 onto the bacteria-repelling filter membrane 1.

[0042] S5. Start the test. Turn on the compressed air source 10 in S1 and adjust the gas flow rate to 70 ml / min. At this time, the pressure value on the intelligent digital pressure gauge 8 is 0 kPa. Take one antibacterial filter from each group for testing. Install the antibacterial filter in the first group on the mounting head 9 to obtain a gas flow rate of Q1 ml / min and a pressure value of F1 kPa. Install the antibacterial filter in the second group on the mounting head 9 to obtain a gas flow rate of Q2 ml / min and a pressure value of F2 kPa. Install the antibacterial filter in the third group on the mounting head 9 to obtain a gas flow rate of Q3 ml / min and a pressure value of F3 kPa. Install the antibacterial filter in the fourth group on the mounting head 9 to obtain a gas flow rate of Q4 ml / min and a pressure value of F4 kPa. Install the antibacterial filter in the fifth group on the mounting head to obtain a gas flow rate of Q5 ml / min and a pressure value of F5 kPa. The specific data are shown in the following table:

[0043]

[0044] S6. Comparison results. First, the first to fourth groups of bacteria-blocking filters are compared, and the following results are obtained: flow rate: Q1>Q2>Q3>Q4, pressure value: F1<F2<F3<F4, which shows that the longer the contact time between the bacteria-blocking filter membrane 1 in the bacteria-blocking filter and the injection liquid, the greater the resistance of the bacteria-blocking filter membrane 1 and the smaller the gas flow rate; then the fifth group of bacteria-blocking filters is compared with the first and fourth groups of bacteria-blocking filters, and the following results are obtained: flow rate: Q5=Q1>Q4, pressure value: F5>F1<F4, which shows that after the one-way diaphragm 3 is set, the resistance will increase when the one-way diaphragm 3 is opened, but the gas flow rate will not be reduced. This shows that when the bacteria-blocking filter equipped with the one-way diaphragm 3 comes into contact with the injection liquid, the one-way diaphragm 3 can effectively prevent the injection liquid from contacting the bacteria-blocking filter membrane 1, so that the bacteria-blocking filter membrane 1 remains dry, and the bacteria-blocking filter membrane 1 can be prevented from being blocked.

[0045] The mounting head 9 involved in this embodiment is as follows Figure 7 As shown, it includes: a rod body 91, a vent hole 92 passing through the rod body 91 is provided in the rod body 91, and a tracheal hole 93 connected to the vent hole 92 is provided at the upper end of the rod body 91. The trachea in the test device is inserted into the tracheal hole 93 and sealed with the tracheal hole 93. The small diameter end of the T-shaped rubber ring 2 in the antibacterial filter is sealed and clamped in the vent hole 92. The lower end wall of the rod body 91 is sealed and fitted on the upper top wall of the large diameter end of the T-shaped rubber ring 2 to block the six through holes 24 on the T-shaped rubber ring 2. In step S4, the antibacterial filter that needs to be in contact with the injection liquid is installed on the mounting head 9, and then comes into contact with the injection liquid. The injection liquid can only come into contact with the antibacterial filter membrane 1 through the bottom of the antibacterial filter, and the injection liquid will not overflow from the top of the T-shaped rubber ring 2 to the antibacterial filter membrane 1. In steps S3 and S5, the antibacterial filter needs to be attached to the mounting head 9 and the six through holes 24 need to be sealed before accurate test data can be obtained.

[0046] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit it. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in the field should understand that the specific implementation methods of the present invention can still be modified or replaced by equivalents. Any modification or equivalent replacement that does not depart from the spirit and scope of the present invention should be covered by the scope of protection of the claims of the present invention.

Claims

1. Diaphragm one-way valve type antibacterial filter for dropper, including: The invention has a hydrophobic bacteria-blocking filter membrane, and a T-shaped rubber ring is injection-molded and compounded on the outer side of the bacteria-blocking filter membrane. An air hole penetrating the T-shaped rubber ring is axially arranged in the T-shaped rubber ring. The bacteria-blocking filter membrane is horizontally placed in the large-diameter end of the T-shaped rubber ring and blocks the air hole. The invention is characterized in that: a mounting groove is extended downward on the T-shaped rubber ring, and a one-way diaphragm is arranged in the mounting groove. The one-way diaphragm includes: an integrally formed positioning ring, an elastic sealing piece and an elastic connecting wire. The positioning ring is clamped in the mounting groove to provide rigid support for the one-way diaphragm. The elastic sealing piece is provided in the mounting groove. The sealing piece is fitted on the bottom wall of the T-shaped rubber ring with zero pressure and seals the air hole, and is used to control the opening and closing of the air hole. The elastic sealing piece and the positioning ring are coaxially arranged, and the elastic connecting wire is evenly distributed between the positioning ring and the elastic sealing piece. When the air flow is sprayed on the elastic sealing piece, the elastic connecting wire controls the elastic sealing piece to open in a directional manner through elastic deformation. When no air hole is sprayed on the elastic sealing piece, the elastic connecting wire controls the elastic sealing piece to close in a directional manner through elastic deformation, so that the elastic sealing piece and the T-shaped rubber ring are re-fitted.

2. The diaphragm one-way valve type bacteria-blocking filter for a dropper according to claim 1, characterized in that: The elastic connecting wire is arc-shaped, and its two ends are respectively arranged on the inner wall of the positioning ring and the outer wall of the elastic blocking piece. The center of the elastic connecting wire is concentric with the center of the elastic blocking piece.

3. The diaphragm one-way valve type bacteria-blocking filter for a dropper according to claim 2, characterized in that: The antibacterial filter membrane is made of PTFE material with a filtration accuracy of 0.2μm. The one-way diaphragm is injection-molded from TPE material. The diameter of the elastic sealing piece in the one-way diaphragm is 2 to 3mm. The upper and lower thicknesses of the elastic connecting wire and the left and right widths of the arc segment are the same, both 0.18 to 0.22mm. The arc length of the elastic connecting wire is 1.2 to 1.25mm, and the central angle is 45°.

4. The diaphragm one-way valve type bacteria-blocking filter for a dropper according to claim 3, characterized in that: An annular groove is provided on the bottom wall of the T-shaped rubber ring, and a positioning convex ring is provided on the top wall of the elastic sealing piece. When the elastic sealing piece is pressed against the T-shaped rubber ring with zero pressure, the positioning convex ring is clamped into the annular groove.

5. The diaphragm one-way valve type bacteria-blocking filter for a dropper according to claim 4, characterized in that: The bottom wall of the elastic sealing piece is a protruding arched pressure wall, which is coaxial with the elastic sealing piece. The maximum diameter of the arched pressure wall is larger than the diameter of the pore. A trumpet-shaped buffer groove is recessed at the center of the top wall of the elastic sealing piece, and the maximum diameter of the trumpet-shaped buffer groove is smaller than the aperture of the pore.

6. The diaphragm one-way valve type bacteria-blocking filter for a dropper according to claim 5, characterized in that: A weight-reducing process groove is provided at the apex of the arched pressure wall.

7. The diaphragm one-way valve type bacteria-blocking filter for a dropper according to claim 1, characterized in that: A shift ring is protruding from the inner wall of the mounting groove. When the positioning ring is clamped in the mounting groove, the outer wall of the positioning ring abuts against the inner wall of the mounting groove, the top wall of the positioning ring abuts against the bottom wall of the T-shaped rubber ring, and the bottom wall of the positioning ring abuts against the shift ring.

8. Air permeability comparison test method, characterized by: Using a bacteria-blocking filter without a one-way diaphragm and the diaphragm one-way valve bacteria-blocking filter for a dropper according to any one of claims 1 to 7, the steps are as follows: S1. Assemble the test device and connect the oil-water separator, pressure reducing valve, fine-tuning valve, gas flow sensor, intelligent digital pressure gauge and mounting head in sequence through the air pipe. The oil-water separator is connected to the compressed air source through the air pipe. S2. Calibrate the test device. Connect the mounting head directly to the external environment. Then, turn on the compressed air source. The compressed air will remain dry after passing through the oil-water separator. The flow rate of the compressed air in the air pipe will be kept constant through the regulation of the pressure reducing valve and the fine-tuning valve. The gas flow sensor will show a constant airflow of 0 ml / min. The gas will be discharged directly from the mounting head into the air. The pressure value displayed on the intelligent digital pressure gauge is 0 kPa. S3. Calibrate the bacteria-repelling filter. Maintaining the gas flow rate in S2, install multiple bacteria-repelling filters without one-way diaphragms on the mounting head in sequence. Observe and record the gas flow rate in the gas flow sensor and the pressure value in the intelligent digital pressure gauge. Then, select the bacteria-repelling filters with the same gas flow rate and pressure value. S4. Classify the bacteria-repelling filters, prepare the injection solution, and divide the bacteria-repelling filters selected in S3 into five groups. The bacteria-repelling filters in the first group are not treated and are kept dry. The bacteria-repelling filters in the second group are in contact with the injection solution for 12 hours. The bacteria-repelling filters in the third group are in contact with the injection solution for 48 hours. The bacteria-repelling filters in the fourth group are in contact with the injection solution for 72 hours. A one-way membrane is provided in the bacteria-repelling filters in the fifth group to form a membrane one-way valve bacteria-repelling filter for a dropper as described in any one of claims 1 to 7. The bacteria-repelling filters are then in contact with the injection solution for 72 hours. When the bacteria-repelling filters are in contact with the injection solution, their bottoms are immersed in the injection solution, and the injection solution does not overflow from the top of the T-shaped rubber ring onto the bacteria-repelling filter membrane. S5. Start the test. Turn on the compressed air source in S1 and adjust the gas flow rate to the same gas flow rate Qml / min as in S2. At this time, the pressure value on the intelligent digital pressure gauge is 0kPa. Install the antibacterial filter in the first group on the mounting head, and obtain a gas flow rate of Q1ml / min and a pressure value of F1kPa. Install the antibacterial filter in the second group on the mounting head, and obtain a gas flow rate of Q2ml / min and a pressure value of F2kPa. Install the antibacterial filter in the third group on the mounting head, and obtain a gas flow rate of Q3ml / min and a pressure value of F3kPa. Install the antibacterial filter in the fourth group on the mounting head, and obtain a gas flow rate of Q4ml / min and a pressure value of F4kPa. Install the antibacterial filter in the fifth group on the mounting head, and obtain a gas flow rate of Q5ml / min and a pressure value of F5kPa. S6. Comparison results: First, the first to fourth groups of bacteria-blocking filters were compared, and the following results were obtained: flow rate: Q1>Q2>Q3>Q4, pressure value: F1<F2<F3<F4, indicating that the longer the contact time between the bacteria-blocking filter membrane and the injection liquid, the greater the resistance of the bacteria-blocking filter membrane and the smaller the gas flow rate; then the fifth group of bacteria-blocking filters was compared with the first and fourth groups of bacteria-blocking filters, and the following results were obtained: flow rate: Q5=Q1>Q4, pressure value: F5>F1<F4, indicating that after setting the one-way diaphragm, the resistance will increase when the one-way diaphragm is opened, but the gas flow rate will not be reduced. This shows that when the bacteria-blocking filter equipped with a one-way diaphragm comes into contact with the injection liquid, the one-way diaphragm can effectively prevent the injection liquid from contacting the bacteria-blocking filter membrane, so that the bacteria-blocking filter membrane remains dry.

9. The air permeability comparison test method according to claim 8, characterized in that: The mounting head includes: a rod body, a vent hole penetrating the rod body is provided in the rod body, a tracheal hole connected to the vent hole is provided at the upper end of the rod body, the trachea in the test device is inserted into the tracheal hole and sealed in place with the tracheal hole, the small-diameter end of the T-shaped rubber ring in the antibacterial filter is sealed and clamped in the vent hole, and the lower end wall of the rod body is sealed and fitted on the upper top wall of the large-diameter end of the T-shaped rubber ring; in S4, the antibacterial filter that needs to be in contact with the injection liquid is installed on the mounting head, and then comes into contact with the injection liquid.

10. The air permeability comparison test method according to claim 8, characterized in that: The injection in S4 is 0.9% NaCl injection.

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