Orthopedic material 3D printing equipment based on stem cells

Abstract

The invention relates to orthopedic material 3D printing equipment based on stem cells, and belongs to the field of 3D printing, the orthopedic material 3D printing equipment comprises bases, supporting plates are installed on the bases, Y-axis sliding seats are installed on the supporting plates, fixing frames are fixedly connected between every two adjacent bases, Z-axis sliding seats are installed on the fixing frames, X-axis sliding seats are installed on the Z-axis sliding seats, and X-axis sliding seats are installed on the X-axis sliding seats. A nozzle is fixedly arranged on the X-axis sliding seat, a feeding port is formed above the nozzle, a first connecting plate is installed on the Y-axis sliding seat, a hot bed is arranged on the first connecting plate, a pressing rod is arranged on the base, a fixing block is welded to the pressing rod, a pressing block is welded to the fixing block, and a clamping groove is formed in the upper portion of the pressing block. And a connecting plate is fixedly arranged on the rear side of the X-axis sliding seat. The problems that a hot bed of an existing 3D printer is generally of a fixed plate face structure, supported or printed materials cannot be rapidly disassembled through a multi-section adjustable hot bed, and a material disc cannot be kept to follow a nozzle all the time are solved.

Description

Technical Field

[0001] The present invention relates to a 3D printing device for orthopedic materials based on stem cells, belonging to the field of 3D printing. Background Art

[0002] 3D printing is a manufacturing technology that fabricates three-dimensional objects by adding materials layer by layer. Different from traditional subtractive manufacturing methods such as cutting and milling, 3D printing is computer-controlled and, based on digital model files, stacks materials layer by layer to form the final object. The core advantage of 3D printing lies in its ability to create complex geometric shapes and it is widely used in multiple fields such as industry, medicine, architecture, aerospace, and education. 3D printing can reproduce complex bone structures and achieve precise repair of bone tissue, but there are still some defects in existing 3D printing devices.

[0003] The invention patent with the publication number CN105345001B discloses a 3D printer for orthopedic titanium alloy internal nail plates, which includes a print head. A fixed plate is provided at the bottom of a cross bar. A first motor and a second motor are provided on the fixed plate. The bottom of the fixed plate is hinged to the print head. The print head is provided with a first fixed shaft and a second fixed shaft. A first wire body is wound around the output shaft of the first motor, and a second wire body is wound around the output shaft of the second motor. The first motor and the second motor are both electrically connected to a PLC. A fan is provided inside the workbench. A fixing device is provided on each side of the fan. The fixing device includes a cylinder and a piston. One end of the cylinder is provided with an end cover, and the other end is provided with a bottom cover. The piston is connected to a fixing rod, and a first spring is provided between the bottom cover and the piston. The print head of this printer is convenient to adjust the angle, and the printed product can be quickly cooled and formed. However, the hot bed of existing 3D printers is usually of a fixed plate surface structure, which is not convenient for subsequent removal of supports with a relatively low height, and it is not possible to quickly remove the supports or the printed materials using a multi-section adjustable hot bed. Moreover, existing 3D printing devices cannot keep the material tray always following the nozzle and ensure that the change in the nozzle height does not affect the position of the material tray when in use.

[0004] Therefore, we make improvements on this and propose a 3D printing device for orthopedic materials based on stem cells. Summary of the Invention

[0005] (1) The technical problem to be solved by the present invention is that the hot bed of existing 3D printers is usually of a fixed plate surface structure, which is not convenient for subsequent removal of supports with a relatively low height, and it is not possible to quickly remove the supports or the printed materials using a multi-section adjustable hot bed. Moreover, existing 3D printing devices cannot keep the material tray always following the nozzle and ensure that the change in the nozzle height does not affect the position of the material tray when in use.

[0006] (2) Technical Solution To achieve the above-mentioned invention purpose, the present invention provides a 3D printing device for orthopedic materials based on stem cells, including a base, on which a support plate is installed, on which a Y-axis slide is installed, a fixing frame is fixedly connected between adjacent two bases, on which a Z-axis slide is installed, on which an X-axis slide is installed, a nozzle is fixedly arranged on the X-axis slide, a feeding port is arranged above the nozzle, a first connecting plate is installed on the Y-axis slide, a hot bed is arranged on the first connecting plate, a pressing rod is arranged on the base, a fixing block is welded on the pressing rod, a pressing block is welded on the fixing block, an adapter plate is fixedly arranged at the rear side of the X-axis slide, a side plate is fixedly connected to the adapter plate, an adapter block is fixedly arranged above the side plate, a second connecting plate is arranged above the adapter block, a buffer assembly is installed between the second connecting plate and the adapter block, a connecting disc and an adjusting assembly are respectively installed on both sides of the second connecting plate, a rotating assembly is arranged in the middle of the connecting disc, a bracket is installed on the rotating assembly, a material tray is rotatably connected to the bracket, and a docking assembly is arranged between the bracket and the material tray.

[0007] Among them, the bases are symmetrically distributed on both sides of the support plate, and the pressing rod is slidably connected to the base.

[0008] Among them, the hot bed includes a fixing plate fixedly connected to the first connecting plate, a connecting shaft is rotatably installed on the fixing plate, a rotating plate is fixedly connected to the connecting shaft, an extension rod is fixedly arranged on the rotating plate, and a convex plate is fixedly arranged on the first connecting plate.

[0009] Among them, an inclined plane is arranged on one side of the extension rod close to the pressing block, the length of the extension rod is greater than the width of the first connecting plate, and the extension rods are equidistantly distributed on the rotating plate.

[0010] Among them, a fixing rod is fixedly connected to the pressing block, a pushing plate is fixedly arranged on the fixing rod, the rotating plate is adapted to rotate counterclockwise when the extension rod abuts against the pressing block, and the pressing rod, the fixing block, the pressing block, the fixing rod and the pushing plate are fixedly connected as an integral structure.

[0011] Among them, the adapter plate and the adapter block are not connected to each other, the adapter block is slidably connected to the fixing frame, a guide rod is slidably installed in the adapter block, and the guide rod is fixedly connected to the side plate.

[0012] Among them, the buffer assembly includes a slider slidably installed in the adapter block, the slider is fixedly connected to the second connecting plate, and both sides of the slider are respectively connected to the adapter block through a first spring and a second spring.

[0013] Among them, the adjusting component includes a sliding rod slidably mounted in the second connecting plate. The sliding rod is fixedly connected to the connecting disc. A stopper is fixedly arranged above the second connecting plate. A third connecting plate is fixedly arranged on the sliding rod. An electric push rod is installed between the third connecting plate and the second connecting plate.

[0014] Among them, the rotating component includes a turntable rotatably mounted in the middle of the connecting disc. The turntable is fixedly connected to the bracket. A first convex block is fixedly arranged on the turntable. A second convex block is fixedly arranged on the connecting disc. A tightening rope is fixedly connected between the first convex block and the second convex block.

[0015] Among them, the docking component includes a first groove opened in the bracket. A rubber damping block is fixedly arranged in the first groove. A rubber ring is fixedly connected to the bracket. A second groove for docking with the rubber damping block is opened on the material tray.

[0016] (III) Beneficial effects The beneficial effects of the 3D printing device for orthopedic materials based on stem cells provided by the present invention are as follows: 1. By providing the first connecting plate and the hot bed, the function of quickly removing the support is realized. By pushing the pressing block, the inclined surface of the pressing block abuts against the extension rod on the hot bed. The extension rods distributed alternately with the convex plates will be lifted as a whole, so that the extension rods on the hot bed are separated from the convex plates, and then the printing materials and the relatively low supports adhered to the extension plate and the convex plates can be quickly detached, enhancing the convenience of the device during use. The device uses a separable hot bed to solve the problem that the existing 3D printing devices cannot quickly remove the support or materials by using a multi-section adjustable hot bed.

[0017] 2. By providing the connecting plate, the side plate and the connecting block, the function of follow-up printing of the material tray is realized. As the X-axis slide moves on the Z-axis slide, the connecting plate will drive the side plate to move synchronously, and the connecting block will slide on the fixed frame, so as to drive the connecting disc and the material tray to move through the second connecting plate, so that the device will move left and right following the print head during printing. And because the side plate and the connecting block are slidably connected in the vertical direction, when the printing nozzle moves up and down, the material tray will remain stationary, ensuring that the feeding consumables can be stable during printing, enhancing the stability of the device during operation, and solving the problem that the existing 3D printing devices cannot keep the material tray always following the nozzle and ensuring that the change in the height of the nozzle does not affect the position of the material tray.

[0018] 3. Through the set buffer component, it is ensured that the tray has a certain buffering function during the process of following the nozzle, ensuring that when printing complex-shaped materials subsequently, the tray will not shake too much during following printing, enhancing the stability of the device during printing. An adjustment component and a rotation component are provided on the device. The tightening rope on the rotation component cooperates with the turntable to enable the angle of the tray to automatically reset after deviation. The adjustment component can adjust the initial position of the tray according to the number of rolls of consumables on the tray, thereby ensuring that the consumables always remain vertical during feeding.

[0019] 4. Through the set docking component, the tray can be quickly docked with the bracket. By squeezing the rubber damping block, the tray can be installed inside the bracket, and the rubber damping block is docked with the second groove, so that the tray can be stably docked with the bracket. The rubber ring makes there be a certain resistance when the tray rotates, thereby ensuring that the consumables are kept in a tightened state during the use of the device. Brief Description of the Drawings

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following-described drawings are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0021] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 It is Figure 1 an enlarged schematic diagram of the structure at A in Figure 3 It is Figure 1 an enlarged schematic diagram of the structure at B in Figure 4 It is a schematic diagram of the connection structure between the base and the support plate of the present invention; Figure 5 It is a schematic diagram of the connection structure between the connecting plate and the side plate of the present invention; Figure 6 It is Figure 5 an enlarged schematic diagram of the structure at C in Figure 7 It is a schematic diagram of the split structure between the connecting block and the second connecting plate of the present invention; Figure 8 It is Figure 7 an enlarged schematic diagram of the structure at D in Figure 9 It is a schematic diagram of the structure between the bracket and the tray of the present invention; Figure 10 It is Figure 9 an enlarged schematic diagram of the structure at E in Figure 11Schematic diagram of the connection structure between the bracket and the docking component of the present invention; Figure 12 Schematic diagram of the cross-sectional structure of the tray of the present invention; Figure 13 Schematic diagram of the connection structure between the first connecting plate and the hot bed of the present invention.

[0022] Reference numerals: 1, base; 2, support plate; 3, Y-axis slide; 4, fixing frame; 5, Z-axis slide; 6, X-axis slide; 7, nozzle; 8, first connecting plate; 9, hot bed; 901, fixing plate; 902, connecting shaft; 903, rotating plate; 904, extension rod; 905, inclined plane; 906, convex plate; 10, pressing rod; 11, fixing block; 12, pressing block; 13, fixing rod; 14, pushing plate; 15, connecting plate; 16, side plate; 17, connecting block; 18, buffer assembly; 1801, slider; 1802, first spring; 1803, second spring; 19, guiding rod; 20, second connecting plate; 21, connecting disc; 22, adjusting assembly; 2201, sliding rod; 2202, stopper; 2203, third connecting plate; 2204, electric push rod; 23, rotating assembly; 2301, turntable; 2302, first convex block; 2303, second convex block; 2304, elastic cord; 24, bracket; 25, tray; 26, feeding port; 27, docking component; 2701, first groove; 2702, rubber damping block; 2703, rubber ring; 2704, second groove; 28, magnetic plate. Detailed description of the invention

[0023] The following further describes in detail the specific implementation manners of the present invention in conjunction with the accompanying drawings of the specification and embodiments. The following embodiments are only used to illustrate the present invention, but cannot be used to limit the scope of the present invention.

[0024] Embodiment 1: As Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Figure 9 , Figure 10 , Figure 11 , Figure 12 and Figure 13As shown in the figure, this embodiment proposes a 3D printing device for orthopedic materials based on stem cells, including a base 1. A support plate 2 is installed on the base 1, and a Y-axis slide 3 is installed on the support plate 2. A fixing frame 4 is fixedly connected between two adjacent bases 1. A Z-axis slide 5 is installed on the fixing frame 4, and an X-axis slide 6 is installed on the Z-axis slide 5. A nozzle 7 is fixedly arranged on the X-axis slide 6. The X-axis slide 6 is used to adjust the left and right positions of the nozzle 7. Above the nozzle 7 is a feeding port 26. The Z-axis slide 5 is used to adjust the up and down positions of the nozzle 7. A first connecting plate 8 is installed on the Y-axis slide 3, and a hot bed 9 is arranged on the first connecting plate 8. The Y-axis slide 3 is used to adjust the front and back positions of the first connecting plate 8 and the hot bed 9. The hot bed 9 can be unfolded in sections to facilitate the subsequent rapid removal of the bonded materials or supports. A pressure rod 10 is arranged on the base 1. A fixing block 11 is welded on the pressure rod 10, and a pressing block 12 is welded on the fixing block 11. The pressing block 12 can abut against the hot bed 9 to enable the hot bed 9 to be conveniently unfolded. A connecting plate 15 is fixedly arranged at the rear side of the X-axis slide 6. A side plate 16 is fixedly connected to the connecting plate 15. An abutting block 17 is fixedly arranged above the side plate 16. Above the abutting block 17 is a second connecting plate 20. A buffer assembly 18 is installed between the second connecting plate 20 and the abutting block 17. Connecting discs 21 and adjusting assemblies 22 are respectively installed on both sides of the second connecting plate 20. A rotating assembly 23 is arranged in the middle of the connecting disc 21. A bracket 24 is installed on the rotating assembly 23. A material tray 25 is rotatably connected to the bracket 24. The adjusting assembly 22 is used to adjust the front and back positions of the material tray 25 to ensure that the consumables on the subsequent material tray 25 are perpendicular during feeding. A docking assembly 27 is arranged between the bracket 24 and the material tray 25, enabling the material tray 25 to be quickly docked or disassembled with the bracket 24. When the X-axis slide 6 slides left and right, the side plate 16 on the connecting plate 15 can abut against the abutting block 17, enabling the second connecting plate 20 to slide left and right following the nozzle 7 through the buffer assembly 18 on the abutting block 17. And when the nozzle 7 moves up and down, the side plate 16 can slide on the abutting block 17 and keep the height of the abutting block 17 unchanged, enabling the material tray 25 on the device to move left and right following the nozzle 7 for printing, and the buffer assembly 18 can play a buffering function during following, ensuring the overall stability of the device.

[0025] Example 2: The solution in Example 1 will be further introduced below in combination with the specific working mode. See the following description for details: As Figure 1 , as a preferred embodiment, on the basis of the above method, further, the bases 1 are symmetrically distributed on both sides of the support plate 2. The pressure rod 10 is slidably connected to the base 1. The pressure rods 10 slidably connected to the two bases 1 facilitate the subsequent rapid removal of the supports with a lower height, enhancing the convenience during the use of the device.

[0026] As Figure 1 andFigure 13 As shown, as a preferred embodiment, on the basis of the above method, further, the hot bed 9 includes a fixing plate 901 fixedly connected to the first connecting plate 8. A connecting shaft 902 is rotatably installed on the fixing plate 901. A rotating plate 903 is fixedly connected to the connecting shaft 902. An extension rod 904 is fixedly arranged on the rotating plate 903. A convex plate 906 is fixedly arranged on the first connecting plate 8. Figure 13 It can be seen from [Figure number not provided] that when the extension rod 904 is pushed upward, the extension rod 904 will rotate on the fixing plate 901 through the rotating plate 903, so as to remove the bonded material or support from the convex plate 906, facilitating the subsequent convenient removal of the support or the printed orthopedic material.

[0027] Such as Figure 1 and Figure 13 As shown, as a preferred embodiment, on the basis of the above method, further, an inclined plane 905 is provided on one side of the extension rod 904 close to the pressing block 12. The length of the extension rod 904 is greater than the width of the first connecting plate 8. The extension rods 904 are evenly distributed on the rotating plate 903. The evenly distributed extension rods 904 ensure the support effect of the device on the orthopedic material. After the inclined plane 905 of the extension rod 904 abuts against the pressing block 12, the extension rod 904 will be lifted. When removing the support or the orthopedic material, the function of rapid removal can be realized without using tools such as a spatula, enhancing the convenience of the device during use.

[0028] Such as Figure 1 and Figure 13 As shown, as a preferred embodiment, on the basis of the above method, further, a fixing rod 13 is fixedly connected to the pressing block 12. A pushing plate 14 is fixedly arranged on the fixing rod 13. The rotating plate 903 is adapted to rotate counterclockwise when the extension rod 904 abuts against the pressing block 12. The pressing rod 10, the fixing block 11, the pressing block 12, the fixing rod 13 and the pushing plate 14 are fixedly connected as an integral structure. When the extension rod 904 is pushed by the pressing block 12, the extension rod 904 will be pushed upward, so that the rotating plate 903 rotates counterclockwise to quickly remove the printed material.

[0029] Such as Figure 13 As shown, as a preferred embodiment, on the basis of the above method, further, a magnetic plate 28 is fixedly connected to the bottom of the extension rod 904. The first connecting plate 8 is made of magnetic metal material. The magnetic plate 28 can stably adsorb the first connecting plate 8, so that the extension rod 904 remains in a stable state during the printing process of the device, ensuring the printing quality of the device and not affecting the subsequent unfolding of the extension rod 904 from the first connecting plate 8.

[0030] Such as Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、Figure 5 , Figure 6 and Figure 7 As shown in Figure 5 , Figure 6 and Figure 7 , as a preferred embodiment, on the basis of the above method, further, the connecting plate 15 and the connecting block 17 are not connected to each other. The connecting block 17 and the fixing frame 4 are slidably connected. A guide rod 19 is slidably installed in the connecting block 17. The guide rod 19 and the side plate 16 are fixedly connected. Figure 7 It can be seen from Figure 7 that when the connecting plate 15 moves downward, the side plate 16 will slide on the connecting block 17, and the guide rod 19 ensures that the side plate 16 can move stably on the connecting block 17 without detachment.

[0031] As Figure 8 shown, as a preferred embodiment, on the basis of the above method, further, the buffer assembly 18 includes a slider 1801 slidably installed in the connecting block 17. The slider 1801 and the second connecting plate 20 are fixedly connected. The two sides of the slider 1801 are respectively connected to the connecting block 17 through a first spring 1802 and a second spring 1803. The first spring 1802 and the second spring 1803 enable the slider 1801 to have a buffering effect while following the movement when the connecting block 17 moves left and right.

[0032] As Figure 1 , Figure 3 , Figure 5 , Figure 6 and Figure 7 shown, as a preferred embodiment, on the basis of the above method, further, the adjusting assembly 22 includes a slide rod 2201 slidably installed in the second connecting plate 20. The slide rod 2201 and the connecting disk 21 are fixedly connected. A stop block 2202 is fixedly arranged above the second connecting plate 20. A third connecting plate 2203 is fixedly arranged on the slide rod 2201. An electric push rod 2204 is installed between the third connecting plate 2203 and the second connecting plate 20. The slide rod 2201 can drive the connecting disk 21 to slide on the second connecting plate 20 when the electric push rod 2204 on the third connecting plate 2203 shortens, so that the device can change the initial position of the consumable according to the number of used rolls of the consumable, ensuring that the consumable always feeds vertically.

[0033] As Figure 6As shown, as a preferred embodiment, on the basis of the above method, further, the rotating assembly 23 includes a turntable 2301 rotatably mounted in the middle of the connecting plate 21. The turntable 2301 and the bracket 24 are fixedly connected. A first convex block 2302 is fixedly arranged on the turntable 2301, and a second convex block 2303 is fixedly arranged on the connecting plate 21. An elastic cord 2304 is fixedly connected between the first convex block 2302 and the second convex block 2303. When the turntable 2301 on the device moves along with the printing position, as the number of usage cycles of the consumable and the position of the consumable change, the turntable 2301 can rotate on the connecting plate 21. The elastic cord 2304 pulls the first convex block 2302 and the second convex block 2303 to reset the turntable 2301.

[0034] As Figure 9 , Figure 10 , Figure 11 and Figure 12 As shown, as a preferred embodiment, on the basis of the above method, further, the docking assembly 27 includes a first groove 2701 opened in the bracket 24. A rubber damping block 2702 is fixedly arranged in the first groove 2701. A rubber ring 2703 is fixedly connected to the bracket 24. A second groove 2704 for docking with the rubber damping block 2702 is opened on the material tray 25. The material tray 25 can squeeze the rubber damping block 2702 to install the material tray 25 onto the bracket 24, so that the rubber damping block 2702 in the first groove 2701 is docked with the second groove 2704 on the material tray 25, thereby quickly disassembling and assembling the material tray 25. The rubber ring 2703 provides a certain resistance when the material tray 25 rotates, so as to ensure that the consumable can be kept straight when feeding, which can not only ensure the printing accuracy but also reduce the probability of blockage.

[0035] Embodiment 3: The solutions in Embodiment 1 and Embodiment 2 are further introduced below in combination with specific working methods. See the following description for details: Specifically, when the 3D printing device for orthopedic materials based on stem cells is in use: As Figure 1 , Figure 2 , Figure 3 and Figure 4 shown, the base 1 and the support plate 2 are used to support the whole device. The X-axis slide 6 is used to adjust the left and right positions of the nozzle 7. The Z-axis slide 5 is used to adjust the up and down positions of the nozzle 7. The Y-axis slide 3 is used to adjust the front and back positions of the first connecting plate 8 and the hot bed 9. The extension rod 904 and the convex plate 906 on the hot bed 9 can be unfolded in sections to quickly remove the bonded material or support. As Figure 9 , Figure 10 , Figure 11 and Figure 12As shown, when the device is in use, the material tray 25 is installed on the bracket 24. When the material tray 25 is installed, it can squeeze the rubber damping block 2702. The rubber damping block 2702 in the first groove 2701 is docked with the second groove 2704 on the material tray 25. The rubber ring 2703 makes the material tray 25 have a certain resistance when rotating, so as to ensure that the consumables can be kept straight when feeding. Vertical feeding can ensure the printing accuracy while reducing the blockage probability of the nozzle 7. The first spring 1802 and the second spring 1803 make the connecting block 17 have a buffering effect while the slider 1801 and the second connecting plate 20 move along with it when the connecting block 17 moves left and right. When the X-axis slide 6 slides left and right on the Z-axis slide 5, the side plate 16 on the connecting plate 15 can abut against the connecting block 17, and the second connecting plate 20 can move left and right along with the nozzle 7 through the buffering component 18 on the connecting block 17. When the nozzle 7 moves vertically on the fixed frame 4 through the Z-axis slide 5, the side plate 16 can slide on the connecting block 17 and keep the height of the connecting block 17 unchanged, so that the material tray 25 on the device can move left and right along with the nozzle 7 for printing, and when the nozzle 7 moves up and down, the material tray 25 is not affected.

[0036] Figure 13 As can be seen, since the pressure bar 10, the fixed block 11, the pressure block 12, the fixed rod 13 and the push plate 14 are an integral body, when the push plate 14 is pushed, the inclined surface of the pressure block 12 can abut against the inclined surface 905 on the extension rod 904, so that the extension rod 904 is lifted, and the rotating plate 903 rotates counterclockwise on the fixed plate 901 through the connecting shaft 902, so that the material or support adhered to the convex plate 906 is removed. When the device removes the support or orthopedic material, tools such as a spatula do not need to be used. When the device uses the printing function, the consumables can be fed vertically, such as Figure 5 、 Figure 6 and Figure 7 As shown, the electric push rod 2204 between the third connecting plate 2203 and the second connecting plate 20 can change the initial position of the material tray 25. The sliding rod 2201 can drive the connecting disk 21 to slide on the second connecting plate 20 when the electric push rod 2204 on the third connecting plate 2203 shortens, so that the device can change the initial position of the consumables according to the number of used rolls of the consumables, ensuring that the consumables are always fed vertically. When the turntable 2301 on the device moves along with the printing position, along with the change of the number of used circles of the consumables and the position of the consumables, the turntable 2301 can rotate on the connecting disk 21 to ensure stable feeding. The tensioning rope 2304 pulls the first convex block 2302 and the second convex block 2303 to reset the turntable 2301 later.

[0037] It should be noted that by extracting stem cells from the patient's own body or a healthy donor, culturing and expanding them in vitro, mixing the cultured stem cells with a biocompatible hydrogel material, 3D printing an orthopedic implant, printing an implant that matches the shape of the defect site according to the three-dimensional data of the patient's bone defect, culturing the printed implant in vitro under specific culture conditions to promote the differentiation of stem cells into osteoblasts, and implanting the mature bone tissue implant into the patient's body to achieve the repair and regeneration of bone tissue. This device uses the patient's own stem cells to reduce immune rejection reactions. The mechanical properties of the implant can be optimized by adjusting the material and structure. Customizing the implant according to the actual situation of the patient can improve the treatment effect. The application of stem cells helps to accelerate the repair and regeneration of bone tissue.

[0038] The above embodiments are only used to illustrate the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the embodiments, those of ordinary skill in the art should understand that various combinations, modifications, or equivalent replacements of the technical solutions of the present invention do not depart from the spirit and scope of the technical solutions of the present invention and should all be covered within the scope of the claims of the present invention.

Claims

1. A 3D printing device for orthopedic materials based on stem cells, comprising a base (1), characterized in that: A support plate (2) is mounted on the base (1), a Y-axis slide (3) is mounted on the support plate (2), a fixing frame (4) is fixedly connected between two adjacent bases (1), a Z-axis slide (5) is mounted on the fixing frame (4), an X-axis slide (6) is mounted on the Z-axis slide (5), a nozzle (7) is fixedly arranged on the X-axis slide (6), a feed port (26) is arranged above the nozzle (7), a first connecting plate (8) is mounted on the Y-axis slide (3), a hot bed (9) is arranged on the first connecting plate (8), a pressure rod (10) is arranged on the base (1), a fixing block (11) is welded on the pressure rod (10), a pressure block (12) is welded on the fixing block (11), the X-axis slide ( A connecting plate (15) is fixedly provided on the rear side of the connecting plate (15), a side plate (16) is fixedly connected to the connecting plate (15), a connecting block (17) is fixedly provided above the side plate (16), a second connecting plate (20) is provided above the connecting block (17), a buffer component (18) is installed between the second connecting plate (20) and the connecting block (17), a connecting disk (21) and an adjusting component (22) are respectively installed on both sides of the second connecting plate (20), a rotating component (23) is provided in the middle of the connecting disk (21), a bracket (24) is installed on the rotating component (23), a material tray (25) is rotatably connected to the bracket (24), and a docking component (27) is provided between the bracket (24) and the material tray (25).

2. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The base (1) is symmetrically distributed on both sides of the support plate (2), and the pressure rod (10) is slidably connected to the base (1).

3. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The hot bed (9) comprises a fixed plate (901) fixedly connected to the first connecting plate (8), a connecting shaft (902) being rotatably mounted on the fixed plate (901), a rotating plate (903) being fixedly connected to the connecting shaft (902), an extension rod (904) being fixedly arranged on the rotating plate (903), and a convex plate (906) being fixedly arranged on the first connecting plate (8).

4. The stem cell-based orthopedic material 3D printing device according to claim 3, characterized in that: A chamfered surface (905) is provided on one side of the extension rod (904) close to the pressing block (12); the length of the extension rod (904) is greater than the width of the first connecting plate (8); and the extension rods (904) are distributed at equal intervals on the rotating plate (903).

5. The stem cell-based orthopedic material 3D printing device according to claim 4, characterized in that: A fixing rod (13) is fixedly connected to the pressing block (12), a push plate (14) is fixedly provided on the fixing rod (13), the rotating plate (903) is adapted to rotate counterclockwise when the extension rod (904) abuts against the pressing block (12), and the pressing rod (10), the fixing block (11), the pressing block (12), the fixing rod (13) and the push plate (14) are fixedly connected to form an integral structure.

6. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The connecting plate (15) and the connecting block (17) are not connected to each other, the connecting block (17) and the fixed frame (4) are slidably connected, a guide rod (19) is slidably mounted in the connecting block (17), and the guide rod (19) and the side plate (16) are fixedly connected.

7. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The buffer assembly (18) comprises a slider (1801) slidably mounted in the connection block (17); the slider (1801) and the second connection plate (20) are fixedly connected; two sides of the slider (1801) are connected to the connection block (17) via a first spring (1802) and a second spring (1803), respectively.

8. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The adjustment assembly (22) comprises a slide bar (2201) slidably mounted in the second connecting plate (20); the slide bar (2201) and the connecting plate (21) are fixedly connected; a stopper (2202) is fixedly arranged above the second connecting plate (20); a third connecting plate (2203) is fixedly arranged on the slide bar (2201); and an electric push rod (2204) is installed between the third connecting plate (2203) and the second connecting plate (20).

9. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The rotating assembly (23) comprises a rotating disk (2301) rotatably mounted in the middle of the connecting disk (21); the rotating disk (2301) and the bracket (24) are fixedly connected; a first protrusion (2302) is fixedly arranged on the rotating disk (2301); a second protrusion (2303) is fixedly arranged on the connecting disk (21); and an elastic rope (2304) is fixedly connected between the first protrusion (2302) and the second protrusion (2303).

10. The stem cell-based orthopedic material 3D printing device according to claim 1, characterized in that: The docking assembly (27) comprises a first groove (2701) formed in the bracket (24), a rubber damping block (2702) being fixedly arranged in the first groove (2701), a rubber ring (2703) being fixedly connected to the bracket (24), and a second groove (2704) for docking with the rubber damping block (2702) being formed on the material tray (25).

Images