Holding device, arrangement comprising holding device, drug delivery device, and method

Abstract

A holding device (10) for holding an object (O) during assembly of a medical device, such as a drug delivery device (100) or an electronic module (EM), comprising a holding structure (HS) and an alignment structure (AS) wherein the holding structure (HS) comprises at least one opening (21-1 to 21-4; 22-1 to 22-4), where the alignment structure (AS) is configured to align an object (O) with respect to the holding structure (HS), where the object (O) comprises a first side (62) of the object (O) and a second side (66) opposite the first side (62), where the first side (62) has a first surface configuration different from a second surface configuration of the second side (66), where the at least one opening (21-1 to 21-4; 22-1 to 22-4) are arranged to apply a negative pressure to a first side (62) of the object (O), and wherein the holding device (10) is configured to hold the object (O) using the negative pressure only in a first orientation in which the first side (62) of the object (O) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), a second orientation in which the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4) in the form of a three-dimensional pattern.

Description

[0001] This disclosure relates to a holding device that can be used to hold an object during the assembly of a device. Pick-and-place techniques are widely used for assembling, for example, electronic devices. Typically, a suction head positioned at the center of an object (e.g., an IC (integrated circuit), discrete electronic component, etc.) is used. Surface mount devices (SMDs) and / or IC packages (e.g., having a lead frame) can be assembled onto a PCB (printed circuit board) or other circuit carrier by a pick-and-place machine. Soldering of the PCB can be the next step to produce a complete PCBA (printed circuit board assembly) or other assembly. However, although pick-and-place techniques have been used for a long time, pick-and-place techniques for special objects (e.g., for button cells (coin cells) and / or objects for which the orientation must be observed) may have limitations. In order to inspect or determine the orientation of these objects during automatic pick-and-place, expensive image processing may be required. SUMMARY OF THE INVENTION

[0002] An object of this disclosure may be to provide an improved holding device. Preferably, the holding device should be able to ensure the correct orientation of an object, for example, during manual or automatic assembly. In addition, a corresponding article and a corresponding method should be provided.

[0003] This object is achieved by a holding device according to claim 1. Further embodiments are given in the dependent claims.

[0004] According to an embodiment, a holding device for holding an object during the assembly of a device (e.g., a medical device) may include at least one, several, or all of the following:

[0005] - a holding structure, and

[0006] - an alignment structure.

[0007] According to an embodiment, the holding structure may include at least one opening. The opening may be configured to provide a gas negative pressure, for example, a suction gas flow that can come from the environment around the holding device and can be directed into the opening.

[0008] According to an embodiment, the alignment structure may be configured to align the object relative to the holding structure (e.g., laterally). This may allow the object to be positioned relative to the at least one opening, especially positioned to allow the object to be specifically held by the suction force applied via the at least one opening depending on the orientation of the object within the holding device.

[0009] According to an embodiment, an object may include a first side of the object and a second side opposite the first side. The first side may have a first surface configuration that is different from a second surface configuration of the second side. This may allow the object to be specifically held, for example, by using the same gas flow that interacts differently with the two sides. The object may be, for example, a battery, in particular a non-rechargeable battery or a rechargeable battery. Another example of an object having two different surface configurations on opposite sides is a transistor within a plastic housing, such as a TO-92 (transistor outline) package. The correct orientation of the device may be critical because otherwise damage to the object and / or other components, in particular electronic components, may occur.

[0010] According to an embodiment, the at least one opening may be arranged to apply a negative pressure to the first side of the object. Providing a negative pressure to the second side may be prevented or mitigated by the second surface configuration (e.g., by a "macroscopic" profile, such as a profile difference of at least 0.5 mm (millimeters) or at least 1 mm). Alternatively or additionally, there may be a difference in the "microscopic" profile of the surface, e.g., a profile difference of less than 0.5 mm (millimeters).

[0011] According to an embodiment, the holding device may be configured to hold the object using negative pressure only in a first orientation and not to hold the object in a second orientation, in the first orientation, the first side of the object faces and / or may abut against the at least one opening, and in the second orientation, the second side faces the at least one opening. Thus, specific holding is provided. Specific holding can be used to at least implicitly check the correct orientation, e.g., the object is held within the holding device in the correct orientation but not in the wrong orientation.

[0012] According to an embodiment, the at least one opening may be at least one slit, such as at least one curved slit (arc-shaped), at least one straight slit, or at least one hole, such as at least one round hole (circular), at least one oval hole, etc. Combinations of holes / slits with different shapes may also be used.

[0013] According to an embodiment, all the openings may have the same shape. Alternatively, different shapes or shapes with different extensions may be used, e.g., in order to provide a uniform suction force.

[0014] The at least one abutment area may provide an abutment area or an abutment surface for the object, for example, in an axial direction. The at least one opening may be arranged in the abutment area. Alternatively, compared to the position of the at least one abutment area, the at least one opening may be arranged at a separate position. The edge of the opening may be used as the abutment area, e.g., the entire edge or only a part of the edge.

[0015] According to an embodiment, the device can be a medical device, such as a drug delivery device, which includes electronic components or electronic modules for generating and / or storing data (e.g., digital data related to drug delivery). If a button cell is applied to the medical device, ensuring the correct orientation (e.g., polarity) of the connection to the electronic circuit can be important for the patient's life. The medical device can be a drug delivery device, such as an autoinjector, an electronic thermometer, a pacemaker, etc. However, the correct polarity can also be important in other devices (e.g., a smart key fob), especially for locking systems, remote control devices, etc.

[0016] According to an embodiment, negative pressure can be applied by a pneumatic system, such as a system including a control unit and / or a system that can be controlled by an operator. Thus, suction can be applied or stopped, for example, by using a foot switch or other suitable switch. However, it is also possible to automatically release an object from the holding device. Turning off the negative pressure can release the object from the holding device in a simple manner. However, additionally or alternatively, (a) other release methods can be used, such as removing the object from the holding device by using a tool.

[0017] The object can be manually inserted into the holding device. Inserting it in an incorrect orientation may, for example, prevent further conveyance of the object. However, automatic insertion is also possible.

[0018] One technical effect of the holding device can be its ability to selectively hold and / or selectively convey an object in the correct orientation against gravity. In an incorrect orientation, the holding force may not be strong enough, and the object may fall out of the holding device due to gravity. Thus, an object orientation selective holding device (ooshd) can be provided.

[0019] In the case of a circular first surface and a circular second surface, different surface configurations can be achieved due to different geometries (e.g., within the edge region) and / or different surface structures and / or different sizes and / or different diameters. This will be described in more detail below. The first surface of the object and the second surface of the object can face in opposite directions.

[0020] The holding device can be configured to hold the object in the holding device when the first surface faces the holding structure and not hold the object in the holding device when the second surface faces the holding structure.

[0021] Image processing may no longer be necessary to detect the orientation of an object, or it can be additionally used, for example, as a double-check. Thus, the holding device provides a very simple and / or cost-effective solution for orienting an object. Errors by a human operator of an assembly device (e.g., inserting an object) can be prevented. However, using the proposed holding device can prevent errors that may also exist in automated production.

[0022] For example, the use of gas / air may be cost-effective compared to other complex mechanically-operated holding devices and / or compared to image processing, etc.

[0023] According to an embodiment, the alignment structure may include at least one alignment region arranged to laterally align an object. The at least one alignment region may be arranged adjacent to the at least one opening, preferably so as to hold the object at at least one edge region of the object and / or provide a high lateral alignment accuracy. "Adjacent" may mean within a range of 0.5% to 5% of the maximum lateral extension of the object. The at least one inlet opening may preferably be located near or close to the lateral alignment surface of the alignment structure. The distance between the lateral alignment surface and the opening (e.g., the edge of the opening) may be less than 2 mm (millimeters) or less than 1 mm, preferably greater than 0.5 mm (which is an example of the lower limit).

[0024] The boundary (perimeter) or edge region of an object may be particularly suitable for achieving a dedicated holding of an object having different edge regions on different sides (e.g., a button cell, a transistor in a plastic housing, etc.). Thus, the object can be held in the edge region in the correct orientation, but not held or only slightly held in the central region, for example because in the central region, there is no different surface configuration allowing the object to be selectively or dedicatedly held within the holding device.

[0025] According to an embodiment, the holding structure may include at least one abutment region configured to abut a second side of the object or alternatively to abut a first side and a second side of the object.

[0026] According to a first embodiment, the at least one opening may be arranged at a different position compared to the at least one abutment region. According to the first embodiment, the at least one opening may be covered only if the object is arranged in the holding device in a first orientation, while the at least one opening is not covered if the object is arranged in the holding device in a second configuration.

[0027] Alternatively or additionally, the at least one opening may be arranged in the at least one abutment region. According to a second embodiment, if the object is arranged in the holding device in a first orientation and if the object is arranged in the holding device in a second configuration, the at least one opening may be covered in both cases. In this case, for example, different surface roughnesses may be used to selectively hold the object only in the first orientation.

[0028] According to an embodiment, different surface configurations may be achieved due to at least one of the following features:

[0029] a) The maximum lateral extent or diameter of the most prominent first surface on the first side of the object is greater than the maximum lateral extent or diameter of the most prominent second surface on the second side of the object. Preferably, the first surface may have a larger surface area compared to the second surface.

[0030] b) The surface roughness of the first surface on the first side of the object is smaller than the surface roughness of the second surface on the second side of the object. Preferably, the first surface may have a smoother surface profile compared to the second surface.

[0031] c) A chamfered or rounded circumferential region on the first side of the object, where there is no such chamfered or rounded circumferential region on the second side of the object. The second side may have, for example, relatively sharp edges compared to the edges on the chamfered or rounded circumferential region. The chamfer may preferably extend along the entire circumference. The rounding may exist not only in the circumferential direction but also in a cross-section including the longitudinal axis of the object and preferably also including the radial axis. Thus, the rotation of the object is irrelevant, and rotational alignment may not be necessary. However, the chamfer may also extend only in at least one region of the circumference of the object and not in at least one other circumferential region of the object. Thus, for example, two chamfered or rounded circumferential regions may be present on the first side of the object, preferably at opposite lateral positions.

[0032] d) Other physical properties adapted to interact with a gas (e.g., air) flow through the at least one opening to achieve specific holding of the object depending on the orientation of the object relative to the holding device.

[0033] According to an embodiment, the holding device may include at least one (optionally selected) or all of the following features:

[0034] a) Wherein the abutment region is arranged to provide an abutment surface for the object in a first direction, preferably in the axial direction of the object. The alignment structure may include at least one lateral holding surface or surface portion configured to align the object in a second direction different from the first direction,

[0035] b) wherein the holding device includes a gas delivery structure. The gas delivery structure may include at least one channel or tube that is connected to or connectable to the at least one opening and is configured to be connected to a negative pressure supply source.

[0036] According to an embodiment, the holding device may include a housing or casing. The holding structure and / or the alignment structure may be provided on or within the housing. The housing may include at least a portion of the gas delivery structure. "Provided" may mean that the corresponding structure may be an integral part of the housing or may be arranged on the housing, for example as a separate part. The gas delivery structure is described below for other embodiments. The use of a housing may allow for a compact holding device to be achieved.

[0037] According to another embodiment, the housing may include at least one, several, or all of the following:

[0038] - a cylindrical outer housing surface. The axis of rotational symmetry of the cylindrical outer housing surface may define the longitudinal axis of the housing,

[0039] - a circular proximal surface, and

[0040] - an annular or substantially annular distal surface, for example not involving air flow (leakage) recesses as described herein.

[0041] The housing may include a cylindrical retention space that extends, for example, from the annular or substantially annular distal surface in the direction of the longitudinal axis of the housing until a circular abutment surface. The circular abutment surface may preferably be arranged coaxially with the longitudinal axis of the housing. The cylindrical retention space may be part of the alignment structure. The circular abutment surface may preferably include at least one opening of the pneumatic subsystem in the circumferential region. The circular abutment surface may be a planar surface.

[0042] According to another embodiment, the housing may preferably include at least one lateral main channel that extends radially and is connected to the at least one opening. The at least one main channel may be configured to be connected to a tube or hose, for example, by inserting at least one tube or hose into the open end of the at least one main channel.

[0043] The cylindrical outer housing surface may extend from the circular proximal surface to the annular distal surface.

[0044] Thus, the housing can be adapted to assemble an object (e.g., a substantially flat cylindrical object) into a medical injection device, in particular into a pen-type device or an auto-injector having the shape of a pen. Exemplarily, the cylindrical outer surface can allow the holding device to be easily aligned with the cylindrical housing of the drug delivery device or with the cylindrical housing of an electronic module configured to be mechanically connected to the drug delivery device, for example. The other technical effects described above can also apply to this housing.

[0045] According to an embodiment, the holding device can include a cylindrical retention space that can be adapted to retain an object and is defined by a retention structure and / or an alignment structure. The diameter of the cylindrical retention space can be slightly larger than the maximum diameter of the object, for example, up to one percent or up to two percent larger, but at least, for example, 0.5% of the object diameter (which is an example of a lower limit). The height of the cylindrical retention space can preferably be in the range from half of the maximum height of the object to the maximum height of the object. Thus, inserting the object into the holding device can be easy. In addition, the object can be released by switching the negative pressure and only using gravity. However, release can also be facilitated by providing positive pressure via the at least one opening and / or by using a separate tool. The cylindrical retention space can be most suitable for a cylindrical button battery because the cylindrical retention space can be complementary to the cylindrical outer shape of the object. By using the cylindrical retention space, easy alignment is possible, especially in all lateral directions. However, it is also feasible to use separate ribs at the boundary of the cylindrical retention space or to use ribs without using the cylindrical retention space at all, for example three ribs or more than three ribs.

[0046] According to an embodiment, at least one first opening of the at least one opening can be arranged at a first position. At least one second opening of the at least one opening can be arranged at a second position. The first position and the second position can be arranged on opposite lateral sides of the retention structure. The first position and the second position can correspond to opposite peripheral regions of a first side of the object.

[0047] Thus, the holding device can be configured such that depending on the first opening being blocked (e.g., closed or almost closed) by a first peripheral region of the first side and at least the second opening being blocked by a second peripheral region of the first side, dedicated retention of the object is achieved. The first peripheral region can not thereby block or close the second opening. The second peripheral region can not thereby block or close the first opening. The "peripheral region" can refer to the part that is the outermost part and is in the range of 60% to 100% or 75% to 100% of the radius of the first side of, for example, a button battery or other object and / or the receiving space for the button battery or another object within the holding device.

[0048] Preferably, the at least one first opening may be part of a first group of the at least one opening. The at least one second opening may be part of a second group of the at least one opening. This may enable an object to be simply held within the holding device on opposite lateral sides (e.g., a disc-shaped object) or ends (e.g., a rod-shaped object). If a group of openings is used, a larger holding area may be provided. This may result in a firmer hold and / or redundancy, e.g., if one of the openings or holes is blocked by dust or the like.

[0049] According to another embodiment, the holes may be arranged around the entire circumference of the retention space, e.g., to provide a greater holding force and / or a more uniform holding force.

[0050] According to an embodiment, the gas delivery structure of the holding device may include at least one of the following:

[0051] a) At least one main channel that may be connected to at least a portion of the at least one opening. The main channel may have a larger cross-sectional area compared to the cross-section of the secondary channels leading to the main channel, e.g., in a cross-section forming an angle in the range of 80 degrees to 100 degrees with the main flow direction. Thus, the main channel may collect the flows of several secondary channels.

[0052] b) A first main channel and a second main channel. The first main channel may be fluidly connected to at least a portion of the at least one opening of the first group, and the second main channel may be different from the first main channel and may be fluidly connected to the openings of the second group. Using two main channels may simplify the gas delivery structure, e.g., avoiding complex (multiple) internal channels. Alternatively, more than two main channels or more than three main channels may be used.

[0053] c) At least one gas flow (leakage) recess adjacent (e.g., close) to the at least one opening, e.g., a laterally (or radially) outwardly recessed recess and / or an axially recessed recess. The at least one gas flow (e.g., gas leakage) recess may be arranged such that when the first side of the object faces the at least one opening, the gas flow between the at least one gas flow recess and the at least one opening may be substantially restricted (blocked) by the object, thereby generating a relatively high suction force of the object to the holding device, and when the second side of the object faces the at least one abutment region and / or at least one opening, the above gas flow may be enabled (substantially unblocked), thereby generating a low suction force to hold the object. Thus, when the second side of the object faces the at least one opening, the object may form a wall, e.g., a wall portion, of the gas channel formed by the at least one gas flow recess and the at least one opening. By providing the at least one gas flow (leakage) recess, e.g., providing an air flow channel, and providing lateral alignment, at least two functions may be combined.

[0054] According to an embodiment, the at least one gas flow recess may be configured such that when the second side faces the at least one opening, at least two gas channels are formed between at least two of the at least one gas flow recess and the at least one opening. When the first side faces the at least one opening, the at least two gas channels between the at least one gas flow recess and the at least two openings may be blocked or at least substantially blocked by an object. Providing gas flow (leakage) recesses for several of these openings may simplify the holding device. However, a 1:1 arrangement of the gas flow recesses and the openings in the at least one opening may also be used.

[0055] According to another embodiment, the at least one gas flow (leakage) recess may be a cylindrical recess or a nearly cylindrical recess, for example open only on one lateral side of the cylinder, especially adjacent to the retention space. Cylindrical recesses can be easily produced using drilling tools. However, other shapes may also be used.

[0056] According to an embodiment, the holding device may include at least one main channel that may be fluidly connected to at least one of the openings and may redirect a gas flow from a first flow direction starting in a suction channel, for example at the at least one opening, to a second flow direction, where the angle between the first direction and the second direction may be in the range of 80 degrees to 100 degrees, preferably 90 degrees or about 90 degrees.

[0057] Preferably, the main channel may include at least one, several (any number) or all of the following:

[0058] a) An inlet portion that includes at least one inlet opening fluidly connected to the suction channel from the at least one opening.

[0059] b) A tube biasing structure or a hose biasing structure that is arranged downstream of the inlet portion of the main channel and is configured to define a bias between the sidewall of the main channel and a tube / hose fluidly connected to the main channel, preferably at the end of the tube / hose disposed within the main channel.

[0060] c) An outlet portion that includes at least one or only one outlet opening, preferably a cylindrical outlet portion or a nearly cylindrical outlet portion.

[0061] The inlet portion may have a cylindrical lower wall. The cylindrical wall (e.g., about half of a cylinder) may be laterally bounded on one side by a flat circular surface or a flat surface in a semi-circular shape. The inlet portion may be open on the side opposite the flat surface. The open side may lead to other parts of the gas delivery structure, such as a space configured to retain one end of a tube or hose.

[0062] Thus, the inlet opening in the cylindrical lower wall may have a lateral offset different from the flat surface due to the circular arrangement of at least one opening for holding an object and the use of a straight channel (e.g., a straight suction channel arranged parallel or substantially parallel to the flat surface) from these openings to the inlet portion.

[0063] Alternatively, the inlet portion may be a curved portion following the curvature of the arc arrangement of the at least one opening for holding an object. Similarly, there may be a cylindrical lower wall including multiple portions of a cylindrical surface. The cylindrical wall may be bounded by a curved circular or semi-circular surface. The same distance from the inlet opening to the curved surface may be used. Similar to that described above, the inlet portion may be open on the side opposite the curved surface. There may be a straight suction channel between the at least one corresponding opening and a corresponding inlet opening. The straight suction channel may be aligned along a curve (e.g., a circular arc curve) following the curve on which the at least one opening is arranged.

[0064] The tube biasing structure or hose biasing structure may provide a retaining function and / or a sealing function for a tube / pipe or a flexible hose. The use of a flexible hose may make the movement of the retaining device easier, e.g., by manual operation. The tube biasing structure or hose biasing structure may be arcuate, e.g., circular arc-shaped, or may have the shape of a semi-disk or any other suitable shape.

[0065] The biasing structure may preferably extend only around a part of the circumference of the circular side, e.g., in the range greater than one-quarter to less than three-quarters of the circumference. The other part(s) of the circumference may be used as an air channel that forms a connection between the channel(s) leading to the at least one opening and other parts of the gas delivery structure. Thus, the biasing structure may form a stop surface for the tube or hose arranged thereon.

[0066] However, alternatively, an external flange may be used to connect a tube / pipe / hose to the main channel by pulling or pushing the pipe or tube onto the flange. This may provide a better fit than an internal arrangement of the tube or pipe, e.g., less air leakage, etc.

[0067] The outlet portion of the main channel can be configured to form an inner surface that can interact with the outer surface of a tube / pipeline or hose to form an airtight connection without the need for further sealing devices or the use of further sealing devices such as gaskets, sealing rings, etc.

[0068] The main channel can be optimized in terms of fluid dynamics to generate a uniform flow profile at the opening within the retention space.

[0069] According to another embodiment, the retention device can be manufactured by 3D (three-dimensional) printing. Layer-by-layer techniques (additive manufacturing) can be used, for example, as opposed to molding techniques that use expensive molds and expensive injection molding machines. Thus, even if only a small number of retention devices are produced, such as fewer than 1000, but for example more than 10 or even more than 100, cost-effective production can be used. Filament printing or flatbed printing can be used. Optionally, a support material can be selectively used for the main material of the retention device, for example, a support material that is soluble in water or other chemical solutions. In addition, the CAD (computer-aided design) data of the 3D printed model can be protected.

[0070] Alternatively, injection molding can be used to produce the retention device based on plastic materials. However, metal can also be used as the material of the retention device, for example, using cutting production machines (subtractive manufacturing).

[0071] According to another aspect, a retention system can include:

[0072] - A retention device according to any one of the foregoing embodiments. The retention device can include at least one opening that is positioned in an area where the at least one opening is covered by an object when the object is in its correct orientation and is not covered or less covered by the object when the object is in its incorrect orientation.

[0073] - A negative pressure source, such as a pump, and

[0074] - A connection system that connects or is configured to connect the retention device and the negative pressure source. The above-described gas delivery structure can be part of the connection system. The connection system can be part of a pneumatic system. The pneumatic system can include, for example, a control unit and / or at least one valve. The control unit can control the negative pressure source and / or the valve to stop or interrupt the delivery of negative pressure, for example, in order to release an object from the retention device.

[0075] Therefore, the technical effects mentioned above for the retention device can also apply to the retention system.

[0076] According to one aspect, the above object is achieved by an arrangement. The arrangement can include:

[0077] - A holding device according to any of the above embodiments or a holding system according to the above embodiments, and

[0078] - An object, which is configured to be held in the holding system for placing the object into the device during the assembly of the device.

[0079] Therefore, the technical effects mentioned above for the holding device can also be applicable to this arrangement.

[0080] According to one aspect, a method of assembling a drug delivery device or an electronic module for a drug delivery device is provided. The method may include at least one, any plurality, or all of the following:

[0081] - Providing or using a holding device according to any of the above embodiments, or providing a holding system according to the above embodiments.

[0082] - Placing an object in the holding device. When the first side faces the at least one opening (e.g., correct orientation), the object can be held within the holding device. When the second side faces the at least one opening (e.g., incorrect orientation), the object or another object of the same type, especially having the same external shape, may fall out of the holding device. This can be considered an implicit check of whether the object is placed in the holding device in the correct or incorrect orientation.

[0083] - Using the holding device to place the object into an object receiving space, such as within the drug delivery device or within the electronic module, or onto the object receiving space. There may be relative movement between the holding device and the device or module to be assembled.

[0084] Therefore, it is ensured that the object is placed in the correct orientation during the assembly of the device or module. For example, where the (multiple) correct electrical contacts contact the positive and negative contacts of the circuit. It can be ensured that the circuit will operate correctly. Importantly, especially in the medical field, for example, the life of a patient can depend on the correct orientation and / or correct polarity of assembling an object (e.g., a button battery) into the device.

[0085] If the object is placed in the holding device in the incorrect orientation, the object will fall out of the holding device due to gravity and due to the low holding force. If an attempt is made to transport an object with an incorrect orientation to the desired position, this will be impossible.

[0086] The release of the object can be achieved by interrupting the negative pressure, for example, by turning off the pump or cutting off the air flow in a suitable manner (e.g., using a valve). The pump of the pneumatic subsystem can be turned off to release, for example, a battery (e.g., a button battery) from the holding device. Alternatively and / or additionally, a tool can be used to release, for example, a battery from the holding device, such as inserting the tool into the gas leakage recess mentioned above or pushing it through from above through a hole extending through the holding device into the retention space.

[0087] Therefore, the technical effects mentioned above for the holding device can also be applicable to this method, and vice versa.

[0088] According to one aspect, there is provided a drug delivery device, in particular a drug delivery device that can be manufactured or is manufacturable (producible) using the above method. The drug delivery device can be, for example, a pen-type device of an axially extending type. The drug delivery device can include at least one, any selected number of, or all of the following:

[0089] - Preferably a housing, such as a housing including a drive mechanism.

[0090] - A container receptacle, for example, provided on or within the housing. The container receptacle can be configured to receive a container containing a drug, see, for example, the drug list mentioned below. Preferably, the container containing the drug can also be included within the drug delivery device, for example, the container can be arranged in the container receptacle. The container can be a cartridge including a coupling structure that couples or can couple to a needle, such as a needle having two sharp ends.

[0091] - An electronic module, which is preferably arranged within or on the housing. The electronic module can be configured to detect drug delivery, in particular the amount of the drug dose delivered or selected. The electronic module can be powered by a power source included within or formed by the object. Compared with the second surface of the object, the first surface of the object can be arranged more proximally. The first surface can be a flat surface that can have a first maximum lateral extension or diameter. The second surface can be a flat surface that can have a second maximum lateral extension or diameter. Preferably, the first maximum lateral extension or diameter can be greater than the second maximum lateral extension or diameter, preferably at least 1% or at least 2% greater than the second maximum lateral extension or diameter. Preferably, compared with the second surface, the first surface can have an opposite electrode polarity. The first maximum lateral extension or diameter can not be greater than 10% or 5% of the second maximum lateral extension or diameter.

[0092] Therefore, the technical effects mentioned above for the holding device can also be applicable to the drug delivery device assembled using the holding device.

[0093] The drug delivery device can be manufactured to enable the use of a standardized button cell. For example, the positive electrode can have a larger surface area compared to the surface of the negative electrode. A chamfer or rounding can be present on the side of the button cell where the negative electrode is arranged.

[0094] Distal can refer to the end of the drug delivery device that is closer to the patient during use of the drug delivery device, for example, the needle tip. Proximal can refer to the opposite side, for example, the distal end of the needle.

[0095] The drug delivery device can include at least one, any selected number, or all of the following:

[0096] - A plunger configured to interact with a stopper in a syringe barrel or another medicament container (e.g., a cartridge).

[0097] - A manually actuated drive sleeve that extends proximally, for example, during dose setting.

[0098] - A retention space for a container containing the drug.

[0099] - Optionally, the container itself,

[0100] - A dose setting mechanism, for example, including a digital sleeve.

[0101] - A cap, etc.

[0102] The drug can be a drug mentioned in the following drug list, for example, insulin.

[0103] The electronic module can be configured to detect drug delivery and / or detect or measure the amount of drug delivered and / or set. The electronic module can include a memory configured to store data regarding the drug, drug delivery time, and / or drug delivery amount. In addition, the electronic module can be configured to establish a data communication link to another device (e.g., a smart phone or a computer device). Thus, the electronic module can be configured to send data and / or receive data, such as digital data. In addition, the electronic module can include any of the parts mentioned below.

[0104] According to another aspect, there is provided an electronic module for a drug delivery device, in particular an electronic module manufactured using the holding device according to any one of the foregoing embodiments. The electronic module may be configured to be mechanically connected to a drug delivery device, in particular to the proximal end of a drug delivery device configured to deliver a drug. The electronic module may be configured to detect drug delivery, in particular the amount of the delivered or selected (set) drug dose. The electronic module may be powered by an object or by the object (e.g., by a button cell). The positive electrode of the object may be arranged more proximally compared to the negative electrode of the object (e.g., button cell). The meaning of "proximal" may be the same as that mentioned above and used for the electronic module coupled to the drug delivery device.

[0105] Furthermore, the electronic module may be configured to establish a data communication link to another device (e.g., a smart phone or a computer device). Bluetooth (SIG, Special Interest Group), Bluetooth Low Energy or other suitable data communication protocols, such as ZigBee (ZigBee Alliance), etc. may be used. The electronic module may include:

[0106] - a microprocessor or a microcontroller (including more peripheral circuits compared to a microprocessor that may be configured to execute operation codes stored in a memory). Alternatively, another control unit, such as a finite state machine (ASIC (application specific circuit), etc.) may be used.

[0107] - at least one motion detection sensor, such as rotation or translation.

[0108] - at least one switch for switching to a second operating mode out of two operating modes, e.g., switching to a high power mode that may consume more power compared to a low power mode. The low power mode may be selected, for example, by an additional switch or after a predetermined time without user action.

[0109] According to a first embodiment, the sensor may include, for example, at least one light tube or two light tubes, e.g., each light tube sending radiation to a rotating part, which, for example, has teeth and recesses between adjacent teeth, and each light tube receiving reflected light from the rotating part. This may be axial detection. This embodiment may allow the combination of the electronic module with a drug delivery device that may also be used without the electronic module. The angular offset may be less than 30 degrees, e.g., using two light tubes.

[0110] According to a second embodiment, the sensor may include, for example, at least one pair or at least two pairs of radiation sources and radiation detectors, such as LEDs (light emitting diodes) and photodiodes or phototransistors, which are arranged, for example, around the circumference of an encoder ring or other rotating part, for example, at an angle of about 135 degrees or other suitable value, for example, in the range of 10 degrees to 140 degrees. The sensor may be arranged on a flexible PCB, for example, so that the sensor can flex to its final sensing position and / or avoid a separate electrical connection between the sensor and the main control unit of the electronic module (e.g., a processor, etc.).

[0111] According to another aspect, a method of holding an object is provided, especially during the assembly of a drug delivery device or an electronic module for a drug delivery device, the method including at least one, any number, or all of the following:

[0112] - Laterally aligning the object. The object may include a first side of the object and a second side opposite the first side. The first side may have a different surface configuration compared to the second side.

[0113] - Applying a negative pressure to the aligned object through at least one opening, for example, to an object aligned by using, for example, an alignment structure.

[0114] - Achieving a specific holding of the object depending on the side of the object adjacent to the at least one opening and depending on the blocking of the at least one opening by the corresponding side of the object (e.g., blocking by an edge region of the object, preferably at the side opposite the first side of the object).

[0115] Thus, the technical effects mentioned above for the holding device can also apply to this method, and vice versa.

[0116] According to another embodiment, the method may include holding the object in its lateral region, but preferably not in the central region. Details have been mentioned above, see the description of the arrangement of the at least one opening. Holding the object laterally can provide a better possibility of specific holding depending on the orientation of the object, which is due to the different surface configurations on the two relevant sides of the object. The method may be combined with any of the above embodiments.

[0117] This application claims the priority of application EP 22315293.5 filed with the EPO in November 2022, the disclosure of which is hereby expressly incorporated by reference for all legal purposes.

[0118] In the following text, a set of aspects is disclosed. These aspects are numbered to facilitate reference to the features of one aspect in other aspects. These aspects form part of the disclosure of the present application and may be made in accordance with independent and / or dependent claims, regardless of what is currently claimed in the present application and also regardless of the reference numerals in parentheses.

[0119] 1. A holding device (10) for holding an object (O) during the assembly of a medical device, the holding device comprising:

[0120] a holding structure (HS), and

[0121] an alignment structure (AS),

[0122] wherein the holding structure (HS) comprises at least one opening (21-1 to 21-4; 22-1 to 22-4),

[0123] wherein the alignment structure (AS) is configured to align the object (O) relative to the holding structure (HS),

[0124] wherein the object (O) comprises a first side (62) of the object (O) and a second side (66) opposite the first side (62),

[0125] wherein the first side (62) has a first surface configuration different from a second surface configuration of the second side (66),

[0126] wherein the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged to apply a negative pressure to the first side of the object (O), and

[0127] wherein the holding device (10) is configured to hold the object (O) using the negative pressure only in a first orientation and not to hold the object in a second orientation, in the first orientation, the first side (62) of the object (O) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), and in the second orientation, the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4).

[0128] 2. The holding device (10) according to aspect 1, wherein the alignment structure (AS) comprises at least one alignment region arranged to laterally align the object (O), and

[0129] wherein the at least one alignment region is arranged adjacent to the at least one opening (21-1 to 21-4; 22-1 to 22-4), preferably to hold the object (O) at at least one edge region of the object (O).

[0130] 3. The holding device (10) according to aspect 1 or 2, wherein the holding structure (HS) includes at least one abutment area (19) configured to abut against the second side of the object or alternatively against the first side (62) and the second side (66),

[0131] wherein the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged at a different position compared to the at least one abutment area (19), or wherein the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged in the at least one abutment area (19).

[0132] 4. The holding device (10) according to any of the preceding aspects, wherein the different surface configurations can be due to at least one of the following features:

[0133] a) The maximum lateral extension or diameter of the most prominent first surface (64) on the first side (62) is greater than the maximum lateral extension or diameter of the most prominent second surface (68) on the second side (66),

[0134] wherein preferably, the first surface (64) has a larger surface area compared to the second surface (68).

[0135] b) The surface roughness of the first surface (64) on the first side (62) is smaller compared to the surface roughness of the second surface (68) on the second side (66).

[0136] c) A chamfered or rounded circumferential area on the first side (62), wherein there is no such circumferential area on the second side (66).

[0137] d) Other physical properties adapted to interact with the gas flow through the at least one opening (21-1 to 21-4; 22-1 to 22-4) to achieve specific holding of the object depending on the orientation of the object (O) relative to the holding device (10).

[0138] 5. The holding device (10) according to any of the preceding aspects, including at least one of the following features:

[0139] a) wherein at least one abutment area (19) is arranged to provide an abutment surface for the object (O) in a first direction, preferably in the axial direction of the object (O), and

[0140] wherein the alignment structure (AS) includes at least one lateral holding surface (20) or surface portion configured to align the object (O) in a second direction different from the first direction.

[0141] b) wherein the holding device (10) includes a gas delivery structure (GTS),

[0142] wherein the gas delivery structure (GTS) includes at least one channel (23-1 to 23-4; 24-1 to 24-4; 25-1, 25-2) or tube (40-1, 40,2), the at least one channel or tube being connected to or connectable to the at least one opening (21-1 to 21-4; 22-1 to 22-4) and being configured to be connected to a negative pressure supply source.

[0143] 6. The holding device (10) according to any one of the foregoing aspects, including a housing (H),

[0144] wherein the holding structure (HS) and / or the alignment structure (AS) is provided on or within the housing (H), and

[0145] wherein the housing (H) includes at least a part of the gas delivery structure (GTS).

[0146] 7. The holding device (10) according to any one of the foregoing aspects, including a cylindrical retention space (18), the cylindrical retention space being adapted to retain the object (O) and being defined by the holding structure (HS) and / or the alignment structure (AS).

[0147] 8. The holding device (10) according to any one of the foregoing aspects, wherein at least one first opening (21-1 to 21-4) of the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged in a first position, and wherein at least one second opening (22-1 to 22-4) of the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged in a second position,

[0148] and wherein the first position and the second position are arranged on opposite lateral sides of the holding structure (HS),

[0149] wherein preferably, the at least one first opening (21-1 to 21-4) is part of a first group (G1) of the at least one opening (21-1 to 21-4; 22-1 to 22-4), and / or wherein the at least one second opening (22-1 to 22-4) is part of a second group (G2) of the at least one opening (21-1 to 21-4; 22-1 to 22-4).

[0150] 9. The holding device (10) according to any of the foregoing aspects, in particular according to aspect 5, wherein the gas transport structure (GTS) comprises at least one of the following:

[0151] a) at least one main channel (25-1, 25-2) that is connected to at least a part of the at least one opening (21-1 to 21-4; 22-1 to 22-4);

[0152] b) a first main channel (25-1) and a second main channel (25-2), the first main channel being fluidly connected to at least a part of the at least one opening (21-1 to 21-4) of the first group (G1), the second main channel being different from the first main channel (25-1) and being fluidly connected to at least a part of the at least one opening (22-1 to 22-4) of the second group (G2);

[0153] c) at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) adjacent to the at least one opening (21-1 to 21-4; 22-1 to 22-4), wherein the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) is arranged such that the gas flow between the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) and the at least one opening (21-1 to 21-4; 22-1 to 22-4) is substantially restricted by the object (O) when the first side of the object (O) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), and is enabled when the second side of the object (O) faces at least one of the at least one opening (21-1 to 21-4; 22-1 to 22-4) and the at least one holding area (19).

[0154] 10. The holding device (10) according to aspect 9, wherein the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) is configured such that when the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), at least two gas channels are formed between the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) and at least two of the at least one opening (21-1 to 21-4; 22-1 to 22-4), and

[0155] Wherein, when the first side (62) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), the at least two gas channels between the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) and the at least two openings (21-1 to 21-4; 22-1 to 22-4) are blocked or at least substantially blocked by the object (O).

[0156] 11. The holding device (10) according to any one of the foregoing aspects, comprising at least one main channel (25-1, 25-2) that is fluidly connected to at least one of the openings (21-1 to 21-4; 22-1 to 22-4) and redirects the gas flow from a first flow direction at the at least one opening (21-1 to 21-4; 22-1 to 22-4) to a second direction, wherein the angle between the first direction and the second direction is in the range of 80 degrees to 100 degrees, preferably 90 degrees or about 90 degrees,

[0157] and wherein preferably the main channel (25-1, 25-2) comprises at least one of the following:

[0158] a) an inlet portion that includes at least one inlet opening fluidly connected to a suction channel from the at least one opening (21-1 to 21-4; 22-1 to 22-4),

[0159] b) a tube or hose biasing structure (27) disposed downstream of the inlet portion of the main channel and configured to define a bias between the sidewall of the main channel and a tube fluidly connected to the main channel,

[0160] c) an outlet portion that includes an outlet opening, preferably a cylindrical outlet portion or a substantially cylindrical outlet portion.

[0161] 12. A holding system, comprising:

[0162] the holding device (10) according to any one of the foregoing aspects,

[0163] a negative pressure source, and

[0164] a connection system that connects or is configured to connect the holding device (10) and the negative pressure source.

[0165] 13. An arrangement (1), comprising the holding device (10) according to any one of aspects 1 to 11 or the holding system according to aspect 12, and an object (O), the object being configured to be held in the holding system to place the object (O) into the device during assembly of the device.

[0166] 14. A method of assembling a drug delivery device (100) or an electronic module (EM) for a drug delivery device (100), the method comprising:

[0167] Providing a holding device (100) according to any one of aspects 1 to 12 or an arrangement (1) according to aspect 13,

[0168] Placing the object (O) in the holding device (10) (240),

[0169] wherein the object (O) is held within the holding device (10) when the first side (62) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), and

[0170] wherein the object (O) or another object (O) falls out of the holding device (10) when the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4),

[0171] Using the holding device (10) to place the object (O) into an object receiving space within the drug delivery device (100) or the electronic module (EM) or onto the object receiving space.

[0172] 15. A drug delivery device (100) manufactured or manufacturable by using the method according to aspect 14,

[0173] Comprising:

[0174] A container receiving portion, wherein the container receiving portion is configured to receive a container (106) containing a drug (Dr, M),

[0175] The container containing the drug (Dr, M), wherein the container (106) is arranged in the container receiving portion, and

[0176] An electronic module (EM),

[0177] wherein the electronic module (EM) is powered by a power source included within or formed by the object (O), and

[0178] wherein the first surface (64) of the object (O) is arranged to be more proximal compared to the second surface (68) of the object (O),

[0179] wherein the first surface (64) is a flat surface having a first maximum lateral extent or diameter,

[0180] wherein the second surface (68) is a flat surface having a second maximum lateral extent or diameter,

[0181] Wherein, the first maximum lateral extent or diameter is greater than the second maximum lateral extent or diameter, and

[0182] Wherein, the first surface (64) has an opposite electrode polarity compared to the second surface (68).

[0183] The fabrication and use of presently preferred embodiments are discussed in detail below. However, it should be understood that the present disclosure provides many applicable concepts that can be implemented in a variety of specific environments. The specific embodiments discussed merely illustrate specific ways of fabricating and using the disclosed concepts and do not limit the scope of the claims.

[0184] Furthermore, unless otherwise specified, the same reference numerals refer to the same technical features. As used in this application, "can" and "may" indicate the possibility of doing so as well as the actual technical implementation. The present concepts of the present disclosure will be described below in a more specific context, namely a drug delivery device, particularly a drug delivery device for humans or animals. However, the disclosed concepts can also be applied to other situations and / or arrangements, such as other syringes, spray devices, or inhalation devices. Alternatively, the proposed holding device and (a) method(s) (e.g., remote control, etc.) can be used to assemble devices in other technical fields.

[0185] The features and technical advantages of the embodiments of the present disclosure have been outlined rather extensively above. Additional features and advantages of the embodiments of the present disclosure will be described below (e.g., the subject matter of the dependent claims). Those skilled in the art should understand that the disclosed concepts and specific embodiments can be readily used as a basis for modifying or designing other structures or processes for achieving the same or similar purposes as the concepts specifically discussed herein. Those skilled in the art should also recognize that equivalent structures do not depart from the spirit and scope of the present disclosure as defined, for example, in the appended claims. BRIEF DESCRIPTION OF THE DRAWINGS

[0186] To more fully understand the presently disclosed concepts and their advantages, reference is now made to the following description in conjunction with the accompanying drawings. The drawings are not drawn to scale. In the drawings, the following are shown:

[0187] Figure 1 is a plan view of a drug delivery device including a dose knob, the dose knob being an example of an application device for an object whose orientation will be correctly defined,

[0188] Figure 2 is a cross-sectional view of an embodiment of an electronic module / dose knob, the electronic module / dose knob being an example of an application device for a button cell, the button cell being an example of an object whose orientation will be correctly defined, wherein the button cell is included in the correct orientation,

[0189] Figure 3 Is Figure 2 A cross-sectional view of an electronic module / dosage knob, in which a button cell is included in an incorrect orientation,

[0190] Figure 4 Is a perspective view of an exemplary embodiment of a component that includes an embodiment of an object orientation-sensitive holding device and a button cell as an exemplary embodiment of an object whose orientation is to be correctly defined, wherein the button cell is held in the receiving area of the device in the correct orientation,

[0191] Figure 5 Is a perspective view of an exemplary embodiment of an object orientation-sensitive holding device,

[0192] Figure 6 Is a cross-sectional view of an exemplary embodiment of a component that includes an object orientation-sensitive holding device and a button cell as an exemplary embodiment of an object, wherein the button cell is held and received in the receiving area of the device in the correct orientation,

[0193] Figure 7 Is Figure 6 A cross-sectional view of a component including an object orientation-sensitive holding device and a button cell, in which the button cell is received in the receiving area of the device in an incorrect orientation, and

[0194] Figure 8 Is a flowchart of a method for providing an object in a correct orientation for use in an application device of the object. Detailed Description

[0195] In the drawings, the same elements, the same kind of elements, and elements that act in the same or similar way may carry the same reference numerals.

[0196] Reference may be made to a cylindrical coordinate system, i.e., each position may be defined by three coordinates: an axial value (height, distance to a zero plane), a radial distance to an axis, and an angle between the current radial position and a plane defined as having a zero angle. In this document, the term "in an axial position" may refer to having an axial coordinate.

[0197] The distal end D may be the end of the needle that is closer to the needle compared to the proximal end P.

[0198] Figure 1 Shows a plan view of a drug delivery device 100 that includes a dosage knob 116 as an example of an application device 90 of an object O whose orientation is to be correctly defined.

[0199] The drug delivery device 100 may be manufactured or may be manufacturable using the methods mentioned below, seeFigure 8 Descriptions and corresponding descriptions. The drug delivery device 100 may include:

[0200] - A housing 102,

[0201] - A container receiving portion, wherein the container receiving portion may be configured to receive a container 106 containing drugs Dr, M, see, for example, the drug list mentioned below.

[0202] - Preferably, the container 106 contains drugs Dr, M, wherein the container 106 may be arranged in the container receiving portion, and

[0203] - An electronic module EM, preferably arranged within or on the housing 102, wherein the electronic module EM may be powered by a power source included within or formed by an object O (see Figures 2 to 7 ).

[0204] A first surface 64 of the object O (see, for example, Figure 2 ) may be arranged to be more proximal P compared to a second surface 68 of the object O (see, for example, Figure 2 ). The first surface 64 may be a flat surface having a first maximum lateral extent or diameter. The second surface 68 may be a flat surface having a second maximum lateral extent or diameter. The first maximum lateral extent or diameter may be greater than the second maximum lateral extent or diameter, preferably at least 1% or at least 2% greater than the second maximum lateral extent or diameter. The first surface 64 may have an opposite electrode polarity, such as a positive electric potential, compared to the second surface 68 which may have, for example, a negative electric potential.

[0205] The window 104 may be used to display the amount of drugs Dr, M selected by a user or patient using the drug delivery device 100. The drug delivery device 100 may be a pen-type device of an axially extending type. The drive sleeve may extend proximally out of the housing 102 during dose selection or dose setting and may be pushed into the housing 102 during drug delivery manually performed by the user. However, the drug delivery device 100 may also be another type of drug delivery device, such as an autoinjector, or a device including a torsion spring to provide a force to support drug delivery or provide all the forces for drug delivery.

[0206] The needle 108 may be attached to the container 106 or the receiving portion of the container 106. The container 106 may be a cartridge and the receiving portion may be a cartridge holder. The needle 108 may have two sharp ends. One end of the needle 108 may be configured to pierce the sealing member of the cartridge. The other end of the needle 108 may be configured to pierce the skin of the patient.

[0207] The needle 108 may be protected by an inner needle cap 110 and an outer needle cap 112 or a cap 114 of the drug delivery device 100.

[0208] The dose of drug Dr or medicament M (e.g., insulin) to be expelled from the drug delivery device 100 can be set by turning the dose knob 116, and then the currently programmed or set dose can be displayed, for example, in multiple units via the dose window 104. This can be achieved by a suitable internal dose setting mechanism of the drug delivery device 100. The markings shown in the dose window 104 can be provided on a dial or a digital sleeve 120.

[0209] The dose knob 116 can also have, for example, an injection button 118 at its proximal end. Alternatively, the dose knob 116 can be configured to act as the injection button 118. When the needle 108 is inserted into a skin portion of the patient and then the dose knob 116 or the injection button 118 is pushed in the axial direction (e.g., distally), the dose of drug (e.g., insulin) contained in the container 106 (the amount of which can be displayed in the dose window 104) will be expelled from the drug delivery device 100.

[0210] The electronic module EM can be arranged within the drug delivery device 100, for example, as an integral part, such as within the dose knob 116. Alternatively, the electronic module EM can be an additional part that can be coupled to the proximal end of the drug delivery device 100, such as clamped, screwed, etc., onto the dose knob 116. The second alternative can allow the electronic module EM to be used on several drug delivery devices 100 of the same type, thus providing multiple uses of the rather expensive electronic module EM. In addition, the user or patient can use only one power source (battery) or a set of power sources for a long time, thus reducing the environmental impact of the production and / or waste disposal of the electronic module EM.

[0211] An electrical energy source can be provided to power the electrical module EM, such as a battery. The battery can be rechargeable or non - rechargeable. An example of a non - rechargeable battery is a battery in the form of a button cell 98, see for example Figure 2 and Figure 3 . An example of a button cell is a CR 1225 type button cell. However, other types of button cells can also be used. According to the international standard IEC (International Electrotechnical Commission) 60086 - 3, "C" represents lithium and "R" represents round.

[0212] Figure 2 A cross - sectional view of an embodiment of the electronic module EM or the dose knob 116 is shown, which is an example of an application device 90 for a button cell 98 (as an example of an object O whose orientation will be correctly defined), where the button cell 98 is included in the correct orientation.

[0213] The object O is, for example, a button cell 98. The button cell 98 may include a first side 62 and a second side 66. The first side 62 may include a first surface 64, for example, a substantially flat surface. The second side 66 may include a second surface 68, for example, a substantially flat surface. The first surface 64 may have a larger diameter and / or a larger surface area compared to the diameter and / or the surface area of the second surface 68.

[0214] The first surface 64 may be part of the positive electrode PE of the button cell 98. The positive electrode PE may also extend circumferentially around the button cell and may extend at the boundary of the second side 66. The second surface 68 may be part of the negative electrode ME of the button cell 98.

[0215] At the second side 66 between the positive electrode PE and the negative electrode ME, an isolation region, such as a sealing ring, may be arranged, which may also perform a sealing function to seal the internal components (e.g., electrochemical components) of the button cell 98 from the outside of the button cell 98, for example, from the ambient gas 30, moisture, dust, etc.

[0216] The external or internal electronic module EM may include a base 91 (e.g., a base). The base 91 may be substantially cylindrical and may be configured to hold the main components of the electronic module EM, such as:

[0217] - a circuit board 92,

[0218] - a button cell 98,

[0219] - electromechanical contact elements that electrically connect the button cell 98 and the circuit board 92,

[0220] - sensor elements (not shown), and / or

[0221] - switching elements (not shown), etc.

[0222] The circuit board 92 may be, for example, a "printed" circuit board (PCB) that carries at least one layer of conductors that look like they are printed on the circuit board, but generally, lithography techniques may be used to manufacture the circuit board 92.

[0223] The circuit board 92 may carry and connect several electronic and / or electromechanical components to form a printed circuit board assembly (PCBA). Examples of components are, for example, processors, conductors, resistors, and / or (multiple) capacitors, etc. Examples of sensor elements are radiation sensors, for example, sensors for electromagnetic radiation, preferably within the visible spectrum or in the UV (ultraviolet) or IR (infrared) regions of the spectrum.

[0224] The contact part (element) that contacts the button cell 98 or other components may include at least one elastic sheet metal element, for example, see the positive electrical contact clip 94. The negative contact element may also include an elastic sheet metal element or another suitable conductive surface. The negative contact element is not shown in Figure 2 and Figure 3 the figures.

[0225] An exemplary positive electrical contact clip 94 may include:

[0226] - a positive electrical contact bridge 95, and

[0227] - at least two positive electrical contact terminals 96 that are connected to the bridge 95, for example, connected to opposite sides of the bridge 95, and are conductively connected to the circuit board 92.

[0228] Other shapes of the positive contact clip 94 are also possible.

[0229] The cover 97 may form the housing of the electronic module EM and may also be arranged on the base 91 (e.g., the base). The dose dial interface may be arranged on the circumference of the electronic module. The injection button interface may be formed on the proximal face of the electronic module EM.

[0230] The rotation axis 99 may be the axis around which the electronic module EM rotates during dose selection (dose setting) and along which the electronic module EM slides during dose injection.

[0231] The following examples relate to the specific assembly of the battery in the correct orientation, for example, relate to a button cell assembly retainer with polarity rejection / detection. However, these concepts can also be applied to other objects O, especially flat objects and / or objects O with different surface configurations in the (multiple) edge regions.

[0232] These embodiments relate to using applied gas suction to retain the button cell 98 or another object O in the assembly tool, see the holding device 10 ( Figures 4 to 7 ), which retains the object when it is correctly oriented and does not retain it when it is incorrectly oriented. Exemplarily, these concepts apply to assembly tools for electronic devices that require a button cell 98 and may be designed to ensure that the button cell is assembled with the correct polarity. This may be particularly useful in a manual assembly line where a human operator may be responsible for selecting the orientation of the button cell 98 or another object O. These embodiments may apply to any component that has an asymmetric geometry with respect to the mid-plane of the object O. The prototype assembly tool incorporating these features performed well in early trials.

[0233] Thus, a manual assembly tool (see, e.g., the holding device 10 or similar device) can enable the button cell 98 or other object O to be retained only when it is correctly oriented, thereby preventing incorrect assembly.

[0234] The correct orientation of the button cell 98 can be Figure 2 the orientation depicted in, e.g., the positive electrode PE being disposed proximal to the negative electrode ME. Thus, the positive electrical contact clip 94 can contact the positive electrode PE on the first side 62 and / or the first surface 64. The negative electrode ME can be directed towards a negative contact portion not shown in Figure 2 and Figure 3 The negative contact portion / component can contact the second surface 68 of the second side 66 to provide a correct electrical connection.

[0235] Figure 3 A cross-sectional view of the electronic module EM / dosage knob 116 of Figure 2 is shown, where the button cells O, 98 are included in the electronic module EM / dosage knob 116 in an incorrect orientation.

[0236] Thus, it may be easy to assemble the button cell 98 onto the additional electronic module EM in two orientations. Each of these orientations connects the button cell with a different polarity. If the button cell is connected to the PCBA with reverse polarity, the voltage will be applied to the circuit in the wrong direction and the electronic module EM will not function. This may also damage the electrical components as they will have a supply voltage outside the absolute maximum rating, so the PCBA will need to be discarded, e.g., because the damage will be invisible and difficult to detect and the assembly error cannot be corrected.

[0237] An incorrect orientation of the button cell 98 can be Figure 3 the orientation depicted in, e.g., where the negative electrode ME is disposed proximal to the positive (+) electrode PE. Thus, the positive electrical contact clip 94 may contact the negative (-) electrode ME on the second side 66 and / or the second surface 68. The positive electrode PE may be directed towards a negative contact portion / component not shown in Figure 2 and Figure 3 The negative contact portion may contact the first surface 64 on the first side 62, thereby providing an incorrect electrical connection.

[0238] Figure 4 A perspective view of an exemplary embodiment of the assembly 1 is shown. The assembly 1 can include an embodiment of the object orientation-sensitive holding device 10 and a button cell 98 as an exemplary embodiment of the object O. The orientation of the button cell 98 is correctly defined, where the button cell 98 is held in the receiving area or the retaining space 18 of the holding device 10 in the correct orientation (see Figure 5) Inside. The button cell 98 in the correct orientation is transferred to the electronic module in the correct orientation, thereby ensuring that the assembly of the button cell 98 into the electronic module also occurs in the correct orientation, as explained in more detail below, see Figure 8 and the corresponding description.

[0239] The holding device 10 can be used to hold an object O (e.g., a button cell 98) during the assembly of a medical device (e.g., a drug delivery device 100) or an electronic module EM that can form part of a medical device (e.g., a drug delivery device 100). The holding device 10 can include:

[0240] - A holding structure HS (see Figure 5 ), see for example Figure 5 the abutment area 19 (abutment surface) in

[0241] - An alignment structure AS, such as the lateral holding surface 20 for example.

[0242] The holding structure HS can include at least one opening 21-1 to 21-4, 22-1 to 22-4, see Figure 5 .

[0243] The alignment structure AS can be configured to laterally align the object O, such as a button cell 98, relative to the holding structure HS. As described above, the object O can include a first side (e.g., 62) of the object O and a second side (e.g., 66) opposite the first side (e.g., 62). The first side (e.g., 62) can have a first surface configuration different from the second surface configuration of the second side (e.g., 66). The at least one opening 21-1 to 21-4, 22-1 to 22-4 can be arranged to apply a negative pressure to the first side (e.g., 62) of the object O. The holding device 10 can be configured to hold the object O using negative pressure only in a first orientation but not hold the object in a second orientation, in the first orientation, the first side (e.g., 62) of the object O faces and / or abuts the at least one opening 21-1 to 21-4, 22-1 to 22-4, in the second orientation, the second side (e.g., 66) faces the at least one opening 21-1 to 21-4, 22-1 to 22-4.

[0244] The housing H of the holding device 10 can include:

[0245] - A first main surface 12, such as a substantially flat annular surface,

[0246] - A second main surface 14, such as a circular flat surface,

[0247] - A cylindrical outer surface 16,

[0248] - A cylindrical retention space 18, see Figure 5 ,

[0249] - Contact area 19 (contact surface), see Figure 5 , and

[0250] - Lateral holding surface 20, such as a cylindrical wall.

[0251] Axis A can extend from the proximal end of housing H to the distal end of housing H. Housing H can have any suitable shape, in particular the outer surface can be modified, for example to be in the shape of a cuboid.

[0252] The cylindrical retention space 18 (see Figure 5 ) can be well adapted to the shape of object O, such as the shape of button cell 98, for example it can have a substantially complementary shape. Thus, the same applies to the contact surface 19 (at least for one side of object O) and the lateral holding surface 20.

[0253] Gas flow recesses 29-1 to 29-3, 29-4 to 29-6 (air leakage recesses if air is used as the gas) can be arranged adjacent to openings 21-1 to 21-4, 22-1 to 22-4, for example see Figure 5 .

[0254] The first gas hose 40-1, in particular the first end 42-1 of gas hose 40-1, can be fluidly connected to openings 21-1 to 21-4. The second gas hose 40-2, in particular the first end 42-2 of gas hose 40-2, can be fluidly connected to openings 22-1 to 22-4. The second ends of the first gas hose 40-1 and the second gas hose 40-2 can be fluidly connected to a negative pressure source, such as a pump device. A Y-shaped connector or other connector including at least three ports can be used to connect the second ends of gas hoses 40-1, 40-2 to the pressure source. Alternatively, two pressure sources or a pressure source including at least two ports can be used.

[0255] The electrical control unit can be connected to the pressure source in order to control the pressure and / or turn on and off the negative pressure source. Alternatively, a valve can be used to turn off or turn on the negative pressure. The valve can be electrically connected to the control unit and fluidly connected to the first gas hose 40-1 and / or the second gas hose 40-2. Alternatively, at least two valves can be used. In addition, the control unit can have an input switch or can be connected to an input switch, which is operated, for example, by the operator's foot, to turn off the negative pressure within the holding device in order to release the object when the object O (e.g., button cell 98) is transported to the final assembly location within the device (e.g., within the drug delivery device 100 or the electronic module EM).

[0256] As Figure 4Depicted, the second side 66 is the lower side and the second surface 68 is the lower surface. This is the correct orientation of the object O, such as a button cell 98, as explained above with reference to Figure 2 as explained.

[0257] The concept described can be used to retain the button cell 98 or another object O in an assembly tool (holding device 10) against gravity using, for example, a negative pressure gas flow that generates suction. An external air flow source capable of generating gas negative pressure can be connected to, for example, a suction array (e.g., openings 21-1 to 21-4) using a hose (e.g., 40-1, 40-2, etc.). The gas hoses, such as 40-1, 40-2, etc., can be assembled to the top tool (holding device 10) by interference fit. The tube biasing surface 28 (see Figure 5 ) can prevent the hose opening from abutting flush against the end face, which would limit the flow. The button cell 98 or another object O can be laterally aligned by a cylindrical holding surface. The gas leakage recesses 29-1 to 29-6 can ensure that the gas flow to the suction array is not restricted by the radial contact between the button cell 98 or another object O and the top tool (holding device 10).

[0258] Figure 5 A perspective view of an exemplary embodiment of an object orientation-sensitive holding device is shown. The alignment structure AS can include at least one alignment region arranged to laterally align the object O, see, for example, the cylindrical wall 20. The at least one alignment region can be arranged (disposed) adjacent to the at least one of the openings 21-1 to 21-4, 22-1 to 22-4, preferably to hold the object O at at least one edge region of the object O.

[0259] The cylindrical wall 20 can be substantially closed along its circumference, for example, disregarding the regions having the gas flow regions 29-1 to 29-6. Alternatively, segments of a circular wall can be used, for example, only two segments, for example, in combination with the gas flow regions 29-1 to 29-6. Between these segments, there can be no lateral alignment region, for example, there can be no wall or there can be another wall (segment) having a different shape, for example, a straight wall (segment).

[0260] The openings 21-1 to 21-4, 22-1 to 22-4 can be grouped into two groups G1, G2, which are separated from each other by a region that does not include the openings. The openings within each group G1, G2 can be arranged in a one-dimensional array of openings. In this example, for instance, seven openings can be arranged along an arc (e.g., a circular arc). Of course, there can be fewer than seven or more than seven openings within the groups G1, G2. The distance, especially the circumferential distance, between adjacent openings 21-1 to 21-4, 22-1 to 22-4 of a group G1, G2 of openings 21-1 to 21-4, 22-1 to 22-4 can be constant. For example, adjacent openings 21-1 to 21-4, 22-1 to 22-4 within a group G1, G2 can be arranged equidistantly. However, different distances can be used between adjacent openings 21-1 to 21-4, 22-1 to 22-4, for example, in order to generate the same suction force for each opening.

[0261] In this example, a group G1, G2 (array) of openings 21-1 to 21-4, 22-1 to 22-4 circumferentially extends only along an angle of less than 30 degrees or less than 20 degrees (e.g., greater than 10 degrees).

[0262] Furthermore, in this example, circular holes are used as the openings 21-1 to 21-4, 22-1 to 22-4. However, alternatively, openings having or including other shapes can also be used, such as relatively short slits or long slits, oval shapes, etc.

[0263] In addition, there can be other possibilities for arranging the openings, such as not forming groups along the entire circumference, or arranging them into more than two groups G1, G2 along the entire circumference.

[0264] The holding structure HS can include at least one abutment region 19, which is configured to abut against the second side 66 of the object O, 98 or alternatively against the first side 62 and the second side 66. The abutment region 19 can extend in a plane, for example, in a circular plane.

[0265] The at least one opening 21-1 to 21-4, 22-1 to 22-4 can be arranged at a different position compared to the at least one abutment region 19. This can cause a separation of the abutment function and the suction function, especially in the case where the second side 66 abuts against the abutment region 19 and the holding of the object O does not occur.

[0266] Alternatively, the at least one opening 21-1 to 21-4, 22-1 to 22-4 can be arranged in the at least one abutment region 19. Thus, the abutment function and the suction function can be closely combined in the abutment region 19.

[0267] Depending on which side of the abutment area the object O faces, there can also be two different abutment areas. Thus, the intermediate abutment area 19 can be used in the case where the second side 66 of the object O, 98 faces the (multiple) abutment areas. In the case where the first side 62 of the object O, 98 faces the abutment area, the abutment areas surrounding the openings 21-1 to 21-4, 22-1 to 22-4 can be used.

[0268] The (multiple) different surface configurations can be due to at least one of the following features:

[0269] a) The maximum lateral extension or diameter of the most prominent first surface 64 on the first side 62 is greater than the maximum lateral extension or diameter of the most prominent second surface 68 on the second side 66. The first surface 64 can have a larger surface area compared to the second surface 68.

[0270] b) The surface roughness of the first surface 64 on the first side 62 is smaller than the surface roughness of the second surface 68 on the second side 66. Thus, the button cell can have a second side 68 carrying a pattern, such as a negative electrode ME. The pattern can result in a greater surface roughness compared to the first side 62 and its first surface 64 (e.g., a positive electrode PE). Thus, the first surface 64 can have a smoother surface profile compared to the second surface 68.

[0271] c) A chamfered circumferential area on the first side 62, where on the second side 66, preferably along the entire circumference, such a chamfered circumferential area may not exist. Thus, the rotation of the object O, 98 about its longitudinal axis is immaterial, for example, rotational alignment may not be necessary. This can typically be used for batteries of the button cell shape type.

[0272] d) Other physical properties adapted to interact with a gas flow (flow), such as an air flow (flow), passing through the at least one opening 21-1 to 21-4, 22-1 to 22-4 to effect a specific holding of the object depending on the orientation of the object O relative to the holding device 10.

[0273] The holding device 10 can have two lateral openings 26-1, 26-2. A biasing structure 27 can be arranged in a recess extending radially inwards from the lateral openings 26-1, 26-2. A biasing surface 28 can be formed on the biasing structure 27. This will be explained in more detail below.

[0274] Figure 6 A cross-sectional view of an exemplary embodiment of the assembly 1 is shown, which includes an object orientation-sensitive holding device 10 and a button cell O, 98 as an exemplary embodiment of the object O, wherein the button cell 98 is held and received in the receiving area (e.g., the cylindrical retention space 18) of the holding device 10 in the correct orientation.

[0275] The holding device 10 may include at least one of the following features:

[0276] a) The at least one abutment region 19 may be arranged to provide an abutment surface for the object O in a first direction, preferably in the axial direction of the object O. The alignment structure AS may include at least one lateral holding surface 20 or surface portion, which is configured to align the object O in a second direction different from the first direction, such as in a lateral direction, such as in Figure 6 the left and right directions in, or in a direction into Figure 6 the plane of, or out of Figure 6 the plane of the paper or display on which Figure 6 is displayed.

[0277] b) The holding device 10 may include a gas delivery structure GTS, such as an air delivery structure. However, other gases may also be used. The gas delivery structure GTS may include at least one of the channels 23-1 to 23-4, 24-1 to 24-4, 25-1, 25-2 or tubes 40-1, 40-2, which are connected to or connectable to the at least one opening 21-1 to 21-4, 22-1 to 22-4 and are configured to be connected to a negative pressure supply source, such as a pump, preferably a diaphragm pump or a membrane pump.

[0278] The holding device 10 may include a housing H. Alternatively, a hose system and a holding plate may be used. The holding structure HS and / or the alignment structure AS may be provided on or within the housing H. In addition, the housing H may include at least a part of the gas delivery structure GTS, such as a gas channel adjacent to the openings 21-1 to 21-4, 22-1 to 22-4. The housing H may be made of plastic or another suitable material (e.g., metal).

[0279] The holding device 10 may include a cylindrical retention space 18, which may be adapted to retain the object O and may be defined by the holding structure HS and / or by the alignment structure AS.

[0280] At least one of the at least one opening 21-1 to 21-4, 22-1 to 22-4, i.e., at least one first opening 21-1 to 21-4, may be arranged at a first position. At least one of the at least one opening 21-1 to 21-4, 22-1 to 22-4, i.e., at least one second opening 22-1 to 22-4, may be arranged at a second position. The first position and the second position may be arranged on opposite lateral sides of the holding structure HS. At least one of the at least one first opening 21-1 to 21-4 or all of the first openings 21-1 to 21-4 may be part of a first group G1 of the at least one opening 21-1 to 21-4, 22-1 to 22-4. At least one of the at least one second opening 22-1 to 22-4 or all of the second openings 22-1 to 22-4 may be part of a second group G2 of the at least one opening 21-1 to 21-4, 22-1 to 22-4.

[0281] The gas delivery structure GTS may include at least one of the following:

[0282] a) At least one main channel 25-1, 25-2, which may be connected to at least a part of the at least one opening 21-1 to 21-4, 22-1 to 22-4.

[0283] b) A first main channel 25-1 and a second main channel 25-2, the first main channel may be fluidly connected to at least a part or all of the at least one opening 21-1 to 21-4 of the first group G1, the second main channel may be different from the first main channel 25-1 and may be fluidly connected to at least a part or all of the at least one opening 22-1 to 22-4 of the second group G2.

[0284] c) At least one gas flow recess 29-1 to 29-3, 29-4 to 29-6, which is adjacent to, for example, close to the at least one opening 21-1 to 21-4, 22-1 to 22-4. The at least one gas flow (e.g., gas leakage) recess 29-1 to 29-3, 29-4 to 29-6 may be arranged such that the gas flow between the at least one gas flow recess 29-1 to 29-3, 29-4 to 29-6 and the at least one opening 21-1 to 21-4, 22-1 to 22-4 is restricted, for example, substantially blocked by the object O when the first side 62 of the object O faces the at least one opening 21-1 to 21-4, 22-1 to 22-4, and is enabled when the second side 66 of the object O faces the at least one opening 21-1 to 21-4, 22-1 to 22-4 and / or the at least one abutting region 19.

[0285] The at least one gas flow recess 29-1 to 29-3, 29-4 to 29-6 may be configured such that, when the second side 66 of the object O faces the at least one opening 21-1 to 21-4, 22-1 to 22-4, at least two gas channels are formed between the at least one gas flow recess 29-1 to 29-3, 29-4 to 29-6 and at least two of the at least one opening 21-1 to 21-4, 22-1 to 22-4. When the first side 62 faces the at least one opening 21-1 to 21-4, 22-1 to 22-4, the at least two gas channels between the at least one gas flow recess 29-1 to 29-3, 29-4 to 29-6 and the at least two openings 21-1 to 21-4, 22-1 to 22-4 may be blocked or at least substantially blocked by the object O.

[0286] It will be understood that more or fewer than three gas flow recesses 29-1 to 29-3, 29-4 to 29-6 may be used on each lateral side of the holding device 10.

[0287] The gas flow recesses 29-1 to 29-3, 29-4 to 29-6 may have a cylindrical shape, for example having an opening side with respect to the cylindrical wall 20. Alternatively, the gas flow recesses 29-1 to 29-3, 29-4 to 29-6 may have other shapes, such as an elliptical bottom surface and an elliptical cross-section parallel to the bottom surface. The gas flow recesses 29-1 to 29-3, 29-4 to 29-6 may also use a cubic shape.

[0288] The main channels 25-1, 25-2 may be fluidly connected to at least one of the openings 21-1 to 21-4, 22-1 to 22-4, preferably to the openings 21-1 to 21-4 of group G1 and the openings 22-1 to 22-4 of group G2 respectively. The main channels 25-1, 25-2 may redirect the gas flow (first flow direction 36) from the at least one opening 21-1 to 21-4, 22-1 to 22-4 to a second direction 38 of gas (e.g., air) flow. The angle between the first direction 36 and the second direction 38 may be in the range of 80 degrees to 100 degrees, preferably about 90 degrees or 90 degrees.

[0289] The main channels 25-1, 25-2 may include at least one of the following:

[0290] a) An inlet portion including at least one inlet opening fluidly connected to a suction channel from the at least one opening 21-1 to 21-4, 22-1 to 22-4. The inlet portion may extend along the lower half of the main channels 25-1, 25-2.

[0291] b) A tube or hose biasing structure 27, which is arranged downstream of the inlet portions of the main channels 25-1, 25-2 and is configured to define a bias between the side walls of the main channels 25-1, 25-2 and the tube or hose 40-1, 40-2 fluidly connected to the main channels 25-1, 25-2, wherein preferably, one end 42-1, 42-2 of the tube / hose 40-1, 40-2 can be arranged within the main channels 25-1, 25-2. The first ends 42-1, 42-2 of the tube or hose 40-1, 40-2 can abut against a biasing surface 28 on the biasing structure 27, thereby defining the distance between the tube or hose 40-1, 40-2 and the opposite side walls of the main channels 25-1, 25-2. This distance can prevent channels 23-1 to 23-4, etc. from being blocked by the hose 40-1, for example, by the first end 42-1 of the hose 40-1. A similar distance can prevent channels 24-1 to 24-4, etc. from being blocked by the hose 40-2, for example, by the first end 42-2 of the hose 40-2.

[0292] c) An outlet portion, which includes an outlet opening, preferably a substantially circular outlet opening. The circular outlet opening can include two semi-circles with different radii, for example, a smaller circle defined by the biasing structure 27 and a larger circle defined by the inlet portion.

[0293] The following channels can exist:

[0294] - Suction channels 23-1 to 23-4, etc. between the inlet portion of the main channel 25-1 and the corresponding openings 21-1 to 21-4, etc., and

[0295] - Suction channels 24-1 to 24-4, etc. between the inlet portion of the main channel 25-1 and the corresponding openings 22-1 to 22-4.

[0296] The negative pressure supply openings 26-1, 26-2 can be fluidly connected to a negative pressure source (not shown) via the hoses 40-1 and 40-2 respectively. Rigid tubes can be used instead of the flexible hoses 40-1 and 40-2. The negative pressure source can be, for example, a pump.

[0297] As Figure 6 shown, the following relatively weak gas flow can be established between the gas (e.g., air) environment 30 and the negative pressure source (e.g., if compared with the Figure 7 corresponding flow shown):

[0298] - Gas flow 32 that passes from the environment 30 through the gas flow recesses 29-2, 29-5, etc., through the small gaps between the first surface 64 and the openings 21-1 to 21-4, etc., 22-1 to 22-4, etc., and reaches the openings 21-1 to 21-4, etc., 22-1 to 22-4, etc. This means that the object O (e.g., a battery in the shape of a button battery 98) can substantially or completely block the resulting gas flow. For example, the flow rate can be less than Figure 7 30% of the corresponding flow rate related in

[0299] - Gas flow 36 that passes from the openings 21-1 to 21-4, etc., 22-1 to 22-4, etc., through the suction channels 23-1 to 23-4, etc., 24-1 to 24-4, etc., and enters the inlet portions of the main channels 25-1, 25-2, respectively.

[0300] - Gas flow 38 that enters the hoses 40-1, 40-2 from the outlet portions of the main channels 25-1, 25-2, respectively.

[0301] - Further gas flow (not shown) that passes through the hoses 40-1, 40-2, an optional connection portion, and / or a valve to reach a negative pressure source (also not shown).

[0302] For example, if compared with the suction force 35 related to the embodiments and arrangements shown in Figure 7 and described in detail below, the generated suction force 34 can be quite high. Therefore, the object O (e.g., the button battery 98) can be held in the orientation shown in Figure 6 with a relatively high holding force. For example, the first normal vector 74 of the first surface 64 (e.g., the positive electrode PE) faces (points to) the holding device 10. The second normal vector 84 of the second surface 68 (e.g., the negative electrode ME) faces away (backs away from) the holding device 10. The holding of the object O, such as the button battery 98, is possible because the holding force is higher than the gravity applied to the object O, 98.

[0303] The holding system may include at least one of the following:

[0304] - The holding device 10 according to any one of the above embodiments,

[0305] - A negative pressure source, and

[0306] - A connection system that connects or is configured to connect the holding device 10 and the negative pressure source.

[0307] The arrangement 1 may comprise a holding device 10 or the holding system according to any of the above embodiments, and an object O, 98, which is configured to be held in the holding system in order to place the object O, 98 in a device or an electronic module EM during the assembly of the device (e.g., device 100 or drug delivery device 100) or the electronic module EM.

[0308] When the operator places a correctly oriented button cell 98 or other object O in the top tool 10, it will cover the suction array, such as openings 21-1 to 22-4, etc., which may be positioned towards the edge of the recess (e.g., the retention space 18), thereby restricting the gas flow. The resulting suction force 34 is greater than the gravitational pull, so the button cell 98 or other object O is held in the top tool (holding device 10).

[0309] Figure 7 Shows Figure 6 A cross-sectional view of an assembly 1 including an object orientation-sensitive holding device 10 and a button cell 98, wherein the button cell 98 or another object is received in the receiving area (e.g., the retention space 18) of the holding device 10 in an incorrect orientation.

[0310] If the operator places an incorrectly oriented button cell 98 or other object O in the top tool (e.g., the holding device 10), the button cell or other object will not cover the suction array (e.g., openings 21-1 to 22-4, etc.) due to, for example, a region of reduced diameter on its negative polarity side (e.g., the negative electrode ME), such that no suction or only very weak suction is applied to the button cell 98 or other object O, and the button cell or other object falls out of the tool, e.g., the holding device 10, under the influence of gravity.

[0311] As Figure 7 shown, the following relatively strong gas flow (e.g., if compared with the corresponding gas flow shown in Figure 6 ) can be established between the gas (e.g., air) environment 30 and the negative pressure source:

[0312] - A gas flow 32 from the environment 30 through the (multiple) gas flow recesses 29-2, 29-5, etc., through the channels formed between the holding device 10 and the boundary or the object O, button cell 98 (e.g., there may be a considerable gap between the edge on the second side 66 of the object O and the openings 21-1 to 21-4, etc., 22-1 to 22-4, etc.) to the openings 21-1 to 21-4, etc., 22-1 to 22-4, etc. This means that the object O (e.g., a battery in the shape of a button cell 98) can allow a gas (e.g., air) flow or flow 32, especially a much higher gas flow 32 than the gas flow 32 associated with the arrangement shown in Figure 6 .

[0313] - The gas flow 36 entering the inlet portions of the main channels 25-1, 25-2 respectively from the openings 21-1 to 21-4 etc., 22-1 to 22-4 etc., through the suction channels 23-1 to 23-4 etc., 24-1 to 24-4 etc. Figure 7 The gas flow 36 shown in Figure 6 can be much higher compared to the gas flow 36 shown in Figure 7 as can be seen from the thicker arrows used in

[0314] - The gas flow 38 entering the hoses 40-1, 40-2 respectively from the outlet portions of the main channels 25-1, 25-2.

[0315] - Further gas flow (not shown) passing through the hoses 40-1, 40-2, optional connecting parts and / or valves to a negative pressure source (also not shown).

[0316] The suction force 35 generated can be relatively low, for example if compared to the suction force 34 related to the embodiments and arrangements shown in Figure 6 and described in detail above, as can be seen from the thinner arrows used in Figure 7 for visualizing the suction force 35. Thus, the object O (e.g., button cell 98) is not held or is held only with a relatively low holding force (e.g., lower than the force generated by or applied by gravity to the object O / button cell 98) in the orientation shown in Figure 7 . For example, the first normal vector 74 of the first surface 64 (e.g., positive electrode PE) faces away (backs away from) the holding device 10. The second normal vector 84 of the second surface 68 (e.g., negative electrode ME) faces (points towards) the holding device 10. Therefore, it is impossible to transport the object O (e.g., button cell 98) to an assembly position, for example to the end of the drug delivery device 100 or to another application device (e.g., electronic module EM or dose knob 116).

[0317] Figure 8 A flowchart of a method 200 for providing an object O (e.g., button cell 98) in the correct orientation for use in an application device 90 of the object O (see Figure 2 and Figure 3 ) is shown. The method of assembling the drug delivery device 100 or the electronic module EM for the drug delivery device 100 may include:

[0318] - Using or providing the holding device 10 or the above-mentioned holding system according to any one of the above embodiments,

[0319] - Placing 240 the objects O, 98 in the holding device 10,

[0320] Wherein, when the first side 62 faces the at least one opening 21-1 to 21-4, 22-1 to 22-4 (e.g., correct orientation), the object O can be held within the holding device 10, and

[0321] wherein, when the second side 66 faces the at least one opening 21-1 to 21-4, 22-1 to 22-4 (e.g., incorrect orientation), the object O or another object O may fall out of the holding device 10.

[0322] - Preferably, the object O, 98 is transported or transferred 260 to the assembly position. Alternatively, other components to be assembled can be transported or conveyed to a position below the holding device 10. The object will only be held within the holding device if the object O, 98 is placed in the holding device 10 in the correct orientation, e.g., see Figure 6 . Otherwise, i.e., if placed in the holding device 10 in the incorrect orientation, it will fall out of the holding device 10 simultaneously, e.g., see Figure 7 .

[0323] - Using the holding device 10, the object O, 98 is placed 270 into the object receiving space within the drug delivery device 100 or the electronic module EM or placed onto the object receiving space, e.g., by turning off the negative pressure of the gas (e.g., air) or by reducing the absolute value of the negative pressure of the gas (air) to release the object.

[0324] More specifically, the method 200 can start from step 210. In step 220, an object orientation-sensitive holding device 10 can be provided, which is used to selectively hold the objects O, 98 according to the orientation 74, 84 of the objects O, 98 relative to the holding device 10. For example, the object orientation-sensitive holding device 10 can be Figures 4 to 7 the holding device 10 shown.

[0325] In step 230, the holding device 10 can be set to operate. The object orientation-sensitive holding device 10 can include a retention space 18 (receiving area), which is adapted to receive the objects O, 98 in a first orientation 74 relative to the holding device 10 or in a second orientation 84 relative to the holding device 10. Herein, if the objects O, 98 are received in the retention space 18 in the first orientation 74 of the objects O, 98 during the operation of the holding device 10, the holding device 10 can be adapted to selectively hold the objects O, 98 in the retention space 18 (as Figure 6 shown). Conversely, if the objects O, 98 are received in the retention space 18 in the second orientation 84 of the objects O, 98 during the operation of the holding device 10, the holding device 10 can be adapted not to hold the objects O, 98 in the retention space 18 (as Figure 7As shown). The negative pressure source can be turned on, or negative pressure can be applied by controlling the corresponding valve(s) of the holding system described above.

[0326] In step 240, a new object O, 98 can be placed in the retention space 18 (receiving area) of the holding device 10, where the object O, 98 is in one of a first orientation 74 and a second orientation 84 relative to the holding device 10. For example, the object O, 98 can be a button cell O, 98, and the application device 90 can be a dosing knob 116, as Figure 2 and Figure 3 shown, or an electronic module EM.

[0327] If the object O, 98 is not held and falls out of the retention space 18 (receiving area), i.e., in step 250 it is N, the process of the method can return to step 240. This can be considered an implicit check of whether the object O, 98 is arranged in the holding device 10 in the correct orientation.

[0328] Step 240 is performed on the same object O, 98 in another orientation or on a new object O, 98 in the correct orientation, for example, placing the same object O, 98 or a new object O, 98 in the retention space 18.

[0329] If the object O, 98 is held in the retention space 18, i.e., in step 250 it is Y, the process of the method can continue to step 260, where the object O, 98 can be transferred from the retention space 18 of the object orientation-sensitive holding device 10 to a new application device 90 (e.g., an electronic module EM) of the object O, 98. As already mentioned above, alternatively or additionally, the device to be assembled can also be transferred or conveyed to a position below the holding device 10.

[0330] In step 270, the gas (air) negative pressure can be turned off, for example, to release the object O, 98 from the holding device 10. The object O, 98 can be directly placed into the device / module to be assembled, for example, at its final assembly location and assembly position. Further, the object O, 98 can be assembled in the same manner. The method 200 can end at step 280.

[0331] The method 200 can include at least one intermediate step not yet described. In addition, other modifications of the method 200 are possible.

[0332] Drug list

[0333] The terms "drug" or "medicament" are used synonymously herein and describe a pharmaceutical preparation that comprises one or more active pharmaceutical ingredients or pharmaceutically acceptable salts or solvates thereof and optionally a pharmaceutically acceptable carrier. In the broadest sense, an active pharmaceutical ingredient ("API") is a chemical structure that has a biological effect on a human or animal. In pharmacology, a drug or medicament is used to treat, cure, prevent or diagnose a disease or to otherwise enhance physical or mental health. A drug or medicament can be used for a limited duration or regularly for a chronic disorder.

[0334] As described below, a drug or medicament can include at least one API or a combination thereof in different types of formulations for the treatment of one or more diseases. Examples of APIs can include small molecules (having a molecular weight of 500 Da or less); polypeptides, peptides and proteins (e.g., hormones, growth factors, antibodies, antibody fragments and enzymes); carbohydrates and polysaccharides; and nucleic acids, double-stranded or single-stranded DNA (including naked and cDNA), RNA, antisense nucleic acids (such as antisense DNA and RNA), small interfering RNA (siRNA), ribozymes, genes and oligonucleotides. Nucleic acids can be incorporated into a molecular delivery system (such as a vector, plasmid or liposome). A mixture of one or more drugs is also contemplated.

[0335] A drug or medicament can be contained in a primary packaging or "drug container" suitable for use with a drug delivery device. The drug container can be, for example, a cartridge, syringe barrel, reservoir or other rigid or flexible vessel that is configured to provide a suitable chamber for storing (e.g., short-term or long-term storage) one or more drugs. For example, in some cases, the chamber can be designed to store the drug for at least one day (e.g., 1 day to at least 30 days). In some cases, the chamber can be designed to store the drug for about 1 month to about 2 years. Storage can be at room temperature (e.g., about 20 °C) or at refrigerated temperature (e.g., about -4 °C to about 4 °C). In some cases, the drug container can be or can include a dual-chamber cartridge that is configured to separately store two or more components of a pharmaceutical preparation to be administered (e.g., an API and a diluent, or two different drugs), one in each chamber. In such cases, the two chambers of the dual-chamber cartridge can be configured to allow mixing between the two or more components before and / or during dispensing into a human or animal body. For example, the two chambers can be configured such that they are in fluid communication with each other (e.g., via a conduit between the two chambers) and allow the user to mix the two components when needed before dispensing. Alternatively or additionally, the two chambers can be configured to allow mixing when the components are dispensed into a human or animal body.

[0336] The drugs or medicaments comprised in a drug delivery device as described herein can be used for treating and / or preventing many different types of medical disorders. Examples of disorders include, for example, diabetes or diabetes-related complications (such as diabetic retinopathy), thromboembolic disorders (such as deep vein or pulmonary thromboembolism). Further examples of disorders are acute coronary syndrome (ACS), angina, myocardial infarction, tumors, macular degeneration, inflammation, hay fever, atherosclerosis and / or rheumatoid arthritis. Examples of APIs and drugs are those described in the following compendia: such as the Rote Liste 2014 (e.g., but not limited to, main group 12 (antidiabetic drugs) or 86 (oncology drugs)) and the Merck Index, 15th edition.

[0337] Examples of APIs for treating and / or preventing type 1 or type 2 diabetes or diabetes-related complications of type 1 or type 2 diabetes include insulin (e.g., human insulin, or human insulin analogues or derivatives); glucagon-like peptide (GLP-1), GLP-1 analogues or GLP-1 receptor agonists, or their analogues or derivatives; dipeptidyl peptidase-4 (DPP4) inhibitors, or pharmaceutically acceptable salts or solvates thereof; or any mixture of the above. As used herein, the terms “analogue” and “derivative” refer to polypeptides having a molecular structure that can be formally derived from the structure of a naturally occurring peptide (e.g., the structure of human insulin) by deletion and / or exchange of at least one amino acid residue present in the naturally occurring peptide and / or by addition of at least one amino acid residue. The added and / or exchanged amino acid residues can be encoded amino acid residues or other naturally occurring residues or purely synthetic amino acid residues. Insulin analogues are also referred to as “insulin receptor ligands”. In particular, the term “derivative” refers to a polypeptide having a molecular structure that can be formally derived from the structure of a naturally occurring peptide (e.g., the structure of human insulin), wherein one or more organic substituents (e.g., fatty acids) are bound to one or more amino acids. Optionally, one or more amino acids present in the naturally occurring peptide may have been deleted and / or replaced by other amino acids (including non-encoded amino acids), or amino acids (including non-encoded amino acids) have been added to the naturally occurring peptide.

[0338] Examples of insulin analogs are Gly(A21), Arg(B31), Arg(B32) human insulin (insulin glargine); Lys(B3), Glu(B29) human insulin (insulin glulisine); Lys(B28), Pro(B29) human insulin (insulin lispro); Asp(B28) human insulin (insulin aspart); human insulin, in which the proline at position B28 is replaced by Asp, Lys, Leu, Val or Ala and in which the Lys at position B29 can be replaced by Pro; Ala(B26) human insulin; Des(B28-B30) human insulin; Des(B27) human insulin and Des(B30) human insulin.

[0339] Examples of insulin derivatives are, for example, B29-N-myristoyl-des(B30) human insulin, Lys(B29)(N-tetradecanoyl)-des(B30) human insulin (insulin detemir, ); B29-N-palmitoyl-des(B30) human insulin; B29-N-myristoyl human insulin; B29-N-palmitoyl human insulin; B28-N-myristoyl LysB28ProB29 human insulin; B28-N-palmitoyl-LysB28ProB29 human insulin; B30-N-myristoyl-ThrB29LysB30 human insulin; B30-N-palmitoyl-ThrB29LysB30 human insulin; B29-N-(N-palmitoyl-γ-glutamyl)-des(B30) human insulin, B29-N-ω-carboxypentadecanoyl-γ-L-glutamyl-des(B30) human insulin (insulin degludec, ); B29-N-(N-lithocholyl-γ-glutamyl)-des(B30) human insulin; B29-N-(ω-carboxyheptadecanoyl)-des(B30) human insulin and B29-N-(ω-carboxyheptadecanoyl) human insulin.

[0340] Examples of GLP-1, GLP-1 analogs and GLP-1 receptor agonists are, for example, lixisenatide exenatide (Exendin-4, a 39-amino acid peptide produced by the salivary gland of the Gila monster), liraglutide semaglutide, taspoglutide, albiglutide dulaglutide rExendin-4, CJC-1134-PC, PB-1023, TTP-054, Langlenatide / HM-11260C (Efpeglenatide), HM-15211, CM-3, GLP-1 Eligen, ORMD-0901, NN-9423, NN-9709, NN-9924, NN-9926, NN-9927, Nodexen, Viador-GLP-1, CVX-096, ZYOG-1, ZYD-1, GSK-2374697, DA-3091, MAR-701, MAR709, ZP-2929, ZP-3022, ZP-DI-70, TT-401 (Pegapamodtide), BHM-034. MOD-6030, CAM-2036, DA-15864, ARI-2651, ARI-2255, Tirzepatide (LY320176), Bamadutide (SAR425899), Exenatide-XTEN, and Glucagon-Xten.

[0341] Examples of oligonucleotides are, for example: mipomersen sodium A cholesterol-reducing antisense therapeutic agent for treating familial hypercholesterolemia or RG012 for treating Alport syndrome.

[0342] Examples of DPP4 inhibitors are linagliptin, vildagliptin, sitagliptin, degliptin, saxagliptin, berberine.

[0343] Examples of hormones include pituitary hormones or hypothalamic hormones or regulatory active peptides and their antagonists, such as gonadotropins (follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, gonadotropin), somatotropin (growth hormone), desmopressin, terlipressin, gonadorelin, triptorelin, leuprorelin, buserelin, nafarelin, and goserelin.

[0344] Examples of polysaccharides include glycosaminoglycans, hyaluronic acid, heparin, low molecular weight heparin or ultra-low molecular weight heparin or their derivatives, or sulfated polysaccharides (e.g., the polysulfated forms of the above polysaccharides), and / or their pharmaceutically acceptable salts. An example of a pharmaceutically acceptable salt of polysulfated low molecular weight heparin is enoxaparin sodium. An example of a hyaluronic acid derivative is Hylan G-F 20 A sodium hyaluronate.

[0345] As used herein, the term "antibody" refers to an immunoglobulin molecule or an antigen-binding portion thereof. Examples of antigen-binding portions of immunoglobulin molecules include F(ab) and F(ab')2 fragments, which retain the ability to bind antigen. Antibodies can be polyclonal, monoclonal, recombinant, chimeric, deimmunized or humanized antibodies, fully human antibodies, non-human (e.g., murine) antibodies, or single-chain antibodies. In some embodiments, the antibody has effector function and can fix complement. In some embodiments, the antibody has reduced or no ability to bind to Fc receptors. For example, the antibody can be an isotype or subtype, an antibody fragment, or a mutant that does not support binding to Fc receptors, e.g., its Fc receptor-binding region has been mutagenized or deleted. The term "antibody" also includes antigen-binding molecules based on tetravalent bispecific tandem immunoglobulins (TBTIs) and / or dual variable domain antibody-like binding proteins having a cross-over binding domain orientation (CODV).

[0346] The term "fragment" or "antibody fragment" refers to a polypeptide (e.g., an antibody heavy chain and / or light chain polypeptide) derived from an antibody polypeptide molecule that does not comprise the full-length antibody polypeptide but still comprises at least a portion of the full-length antibody polypeptide that is capable of binding to an antigen. Antibody fragments can comprise a cleaved portion of the full-length antibody polypeptide, but the term is not limited to such cleaved fragments. Antibody fragments useful in the present invention include, for example, Fab fragments, F(ab')2 fragments, scFv (single-chain Fv) fragments, linear antibodies, monospecific or multispecific antibody fragments (such as bispecific, trispecific, tetra-specific, and multispecific antibodies (e.g., diabodies, triabodies, tetra-bodies)), monovalent or multivalent antibody fragments (such as divalent, trivalent, tetravalent, and multivalent antibodies), minibodies, chelating recombinant antibodies, triabodies or diabodies, intracellular antibodies, nanobodies, small modular immunopharmaceuticals (SMIPs), binding domain immunoglobulin fusion proteins, camelized antibodies, and antibodies containing VHHs. Additional examples of antigen-binding antibody fragments are known in the art.

[0347] The term "complementary determining region" or "CDR" refers to short polypeptide sequences within the variable regions of both the heavy chain polypeptide and the light chain polypeptide that are primarily responsible for mediating specific antigen recognition. The term "framework region" refers to the amino acid sequences within the variable regions of both the heavy chain polypeptide and the light chain polypeptide that are not CDR sequences and that are primarily responsible for maintaining the correct positioning of the CDR sequences to allow antigen binding. Although framework regions typically do not directly participate in antigen binding as is known in the art, certain residues within the framework regions of certain antibodies can directly participate in antigen binding or can affect the ability of one or more amino acids in the CDR to interact with the antigen.

[0348] Examples of antibodies are anti-PCSK-9 mAb (e.g., alirocumab), anti-IL-6 mAb (e.g., sarilumab), and anti-IL-4 mAb (e.g., dupilumab).

[0349] Additional examples of APIs for the prevention of hemophilia A or B (with or without inhibitors) include siRNAs that target antithrombin. An example of an siRNA that targets antithrombin is fitusiran. The terms “prevention” and “preventive treatment” are used interchangeably herein.

[0350] Also contemplated is the use of pharmaceutically acceptable salts of any of the APIs described herein in a drug or medicament in a drug delivery device. Pharmaceutically acceptable salts are, for example, acid addition salts and basic salts.

[0351] Those skilled in the art will understand that the different components, formulations, instruments, methods, systems, and embodiments of the APIs described herein can be modified (added to and / or removed) without departing from the full scope and spirit of the invention, and the invention encompasses such modifications and any and all equivalents thereof.

[0352] Example drug delivery devices can relate to needle-based injection systems as described in Table 1 of Section 5.2 of ISO 11608-1:2014(E). As described in ISO 11608-1:2014(E), needle-based injection systems can be broadly divided into multi-dose container systems and single-dose (partially or fully emptied) container systems. The container can be a replaceable container or an integral non-replaceable container.

[0353] As further described in ISO 11608-1:2014(E), a multi-dose container system can relate to a needle-based injection device with a replaceable container. In such a system, each container holds multiple doses, and the sizes of these doses can be fixed or variable (predetermined by the user). Another multi-dose container system can relate to a needle-based injection device with an integral non-replaceable container. In such a system, each container holds multiple doses, and the sizes of these doses can be fixed or variable (predetermined by the user).

[0354] As further described in ISO 11608-1:2014(E), a single-dose container system can involve a needle-based injection device having a replaceable container. In one example of such a system, each container holds a single dose, where the entire deliverable volume is discharged (fully emptied). In another example, each container holds a single dose, where a portion of the deliverable volume is discharged (partially emptied). Also as described in ISO 11608-1:2014(E), a single-dose container system can involve a needle-based injection device having an integral non-replaceable container. In one example of such a system, each container holds a single dose, where the entire deliverable volume is discharged (fully emptied). In another example, each container holds a single dose, where a portion of the deliverable volume is discharged (partially emptied).

[0355] Although the embodiments of the present disclosure and their advantages have been described in detail, it should be understood that various changes, substitutions, and alterations can be made therein without departing from the spirit and scope of the present disclosure as defined by the appended claims. For example, those skilled in the art will readily understand that many of the features, functions, processes, and methods described herein can be changed while still remaining within the scope of the present disclosure. Additionally, the scope of the present application is not intended to be limited to the specific embodiments of the systems, processes, manufacturing, methods, or steps described in the present disclosure. Those of ordinary skill in the art will readily understand from the disclosure of the present disclosure that systems, processes, manufacturing, methods, or steps that currently exist or will be developed later and that perform substantially the same functions or achieve substantially the same results as the corresponding embodiments described herein can be utilized in accordance with the present disclosure. Accordingly, the appended claims are intended to include such systems, processes, methods, or steps within their scope. The embodiments mentioned in the first part of this specification can be combined with each other. The embodiments described in the drawings can also be combined with each other. Further, the embodiments mentioned in the first part of the specification can be combined with the examples in the second part of the specification Figures 1 to 8 referred to herein.

[0356] Reference numerals

[0357] 1 Arrangement

[0358] 10 Holding device

[0359] 12 First major surface

[0360] 14 Second major surface

[0361] 16 Cylindrical outer surface

[0362] 18 Cylindrical retention space

[0363] 19 Contact area (surface)

[0364] 20 Lateral holding surface (cylindrical wall)

[0365] 21-1 to 21-4 etc. Suction openings

[0366] 22-1 to 22-4 etc. Suction openings

[0367] G1, G2 Groups

[0368] 23-1 to 23-4 Suction channels

[0369] 24-1 to 24-4 Suction channels

[0370] 25-1, 25-2 Main channels

[0371] 26-1, 26-2 Negative pressure supply openings

[0372] 27 Biasing structure

[0373] 28 Biasing surface

[0374] 29-1 to 29-3 Gas flow recesses (air)

[0375] 29-4 to 29-6 Gas flow recesses (air)

[0376] 30 Gas environment

[0377] 32 Gas flow

[0378] 34, 35 Suction force

[0379] 36, 38 Gas flow

[0380] 40-1, 40-2 Gas hoses

[0381] 42-1, 42-2 First ends

[0382] O Object (e.g., button cell)

[0383] 62 First side

[0384] 64 First surface

[0385] 66 Second side

[0386] 68 Second surface

[0387] PE Positive electrode

[0388] ME Negative electrode

[0389] EM Electronic module

[0390] Dr, M Drugs, medicaments

[0391] P Proximal

[0392] D Distal

[0393] A Axis

[0394] H Housing

[0395] AS Alignment Structure

[0396] HS Holding Structure

[0397] GTS Gas Transfer Structure

[0398] 74 First Normal Vector

[0399] 84 Second Normal Vector

[0400] 90 Application Device / Component

[0401] 91 Base

[0402] 92 Circuit Board

[0403] 93 Negative Electrical Contact (and / or Electronic Component, Capacitor, etc.)

[0404] 94 Positive Electrical Contact Clip

[0405] 95 Positive Electrical Contact Bridge

[0406] 96 Positive Electrical Contact End

[0407] 97 Cover

[0408] 98 Electrical Component / Button Cell / Object

[0409] 99 Rotation Axis

[0410] 100 Injection Device

[0411] 102 Housing

[0412] 104 Window

[0413] 106 Container

[0414] 108 Needle

[0415] 110 Inner Needle Cap

[0416] 112 Outer Needle Cap

[0417] 114 Other Cap

[0418] 116 Dose Knob

[0419] 118 Injection Button

[0420] 120 Dial or Digital Sleeve

[0421] 200 Method for providing correct orientation of an object

[0422] 210 Start

[0423] 220 Provide an object orientation-sensitive holding device

[0424] 230 Set the device in operation

[0425] 240 Place a new object in the receiving area of the object orientation-sensitive holding device

[0426] and

[0427] 250 Check if the object is held in the receiving area

[0428] 260 Transfer the object from the receiving area to a new application device

[0429] 270 Turn off the gas negative pressure

[0430] 280 End

Claims

1. A holding device (10) for holding an object (O) during the assembly of a medical device (100), comprising: Retention structure (HS), and Alignment structure (AS), wherein the retention structure (HS) includes at least one opening (21-1 to 21-4; 22-1 to 22-4), wherein the alignment structure (AS) is configured to align an object (O) relative to the retention structure (HS), wherein the object (O) is a button cell, wherein the object (O) includes a first side (62) of the object (O) and a second side (66) opposite the first side (62), wherein the first side (62) has a first surface configuration different from a second surface configuration of the second side (66), wherein the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged to apply a negative pressure to the first side of the object (O), and wherein the holding device (10) is configured to hold the object (O) using the negative pressure only in a first orientation and not to hold the object in a second orientation, in the first orientation, the first side (62) of the object (O) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), and in the second orientation, the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4).

2. The holding device (10) according to claim 1, wherein, The alignment structure (AS) includes at least one alignment region configured to laterally align the object (O), and wherein the at least one alignment region is arranged adjacent to the at least one opening (21-1 to 21-4; 22-1 to 22-4) to hold the object (O) at at least one edge region of the object (O).

3. The holding device (10) according to claim 1 or 2, wherein, The retention structure (HS) includes at least one abutment region (19), the at least one abutment region being configured to abut the second side of the object or alternatively to abut the first side (62) and the second side (66), wherein the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged at a different position compared to the at least one abutment region (19), or wherein the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged in the at least one abutment region (19).

4. The holding device (10) according to any one of the preceding claims, wherein, These different surface configurations are due to at least one of the following features: a) The maximum lateral extension or diameter of the most prominent first surface (64) on the first side (62) is greater than the maximum lateral extension or diameter of the most prominent second surface (68) on the second side (66), b) The surface roughness of the first surface (64) on the first side (62) is smaller than the surface roughness of the second surface (68) on the second side (66), c) A circumferential region on the first side (62) that is chamfered or rounded, where there is no such circumferential region on the second side (66), d) Other physical properties adapted to interact with the gas flow through the at least one opening (21-1 to 21-4; 22-1 to 22-4) to effect a specific retention of the object depending on the orientation of the object relative to the holding device (10).

5. The holding device (10) according to any one of the preceding claims, comprising at least one of the following features: a) wherein, At least one abutment area (19) is arranged to provide an abutment surface for the object (O) in a first direction, and wherein the alignment structure (AS) comprises at least one lateral holding surface (20) or surface portion, the at least one lateral holding surface or surface portion being configured to align the object (O) in a second direction different from the first direction, b) wherein the holding device (10) comprises a gas delivery structure (GTS), wherein the gas delivery structure (GTS) comprises at least one channel (23-1 to 23-4; 24-1 to 24-4; 25-1, 25-2) or tube (40-1, 40,2), the at least one channel or tube being connected to or connectable to the at least one opening (21-1 to 21-4; 22-1 to 22-4) and being configured to be connected to a negative pressure supply source.

6. The holding device (10) according to any one of the preceding claims, comprising a housing (H), wherein, The holding structure (HS) and the alignment structure (AS) are provided on or within the housing (H), and wherein the housing (H) comprises at least a part of the gas delivery structure (GTS).

7. The holding device (10) according to any one of the preceding claims, comprising a cylindrical retention space (18) that is adapted to retain the object (O) and is defined by the holding structure (HS) and the alignment structure (AS).

8. The holding device (10) according to any one of the preceding claims, wherein,At least one first opening (21-1 to 21-4) of the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged in a first position, and wherein at least one second opening (22-1 to 22-4) of the at least one opening (21-1 to 21-4; 22-1 to 22-4) is arranged in a second position, and wherein the first position and the second position are arranged on opposite lateral sides of the holding structure (HS), and / or wherein the holding device (10) is configured such that the object (O) is held by an air negative pressure applied through the at least one opening (21-1 to 21-4; 22-1 to 22-4) in the edge region of the object (O) in the first orientation, but not applied or only slightly applied at the central region.

9. The holding device (10) according to any one of the preceding claims, in particular according to claim 5, wherein, The gas delivery structure (GTS) comprises at least one of the following: a) at least one main channel (25-1, 25-2), the at least one main channel being connected to at least a part of the at least one opening (21-1 to 21-4; 22-1 to 22-4), b) a first main channel (25-1) and a second main channel (25-2), the first main channel being fluidly connected to at least a part of the at least one opening (21-1 to 21-4) of a first group (G1), the second main channel being different from the first main channel (25-1) and being fluidly connected to at least a part of the at least one opening (22-1 to 22-4) of a second group (G2), c) at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) adjacent to the at least one opening (21-1 to 21-4; 22-1 to 22-4), wherein the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) is arranged such that the gas flow between the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) and the at least one opening (21-1 to 21-4; 22-1 to 22-4) is substantially restricted by the object (O) when the first side of the object (O) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), and is enabled when the second side of the object (O) faces at least one of the at least one opening (21-1 to 21-4; 22-1 to 22-4) and the at least one holding area (19).

10. The holding device (10) according to claim 9, alternative c), wherein, The at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) is configured such that when the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), at least two gas channels are formed between the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) and at least two of the at least one opening (21-1 to 21-4; 22-1 to 22-4), and wherein when the first side (62) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), the at least two gas channels between the at least one gas flow recess (29-1 to 29-3; 29-4 to 29-6) and the at least two openings (21-1 to 21-4; 22-1 to 22-4) are blocked or at least substantially blocked by the object (O).

11. The holding device (10) according to any one of the preceding claims, comprising at least one main channel (25-1, 25-2) which is fluidly connected to at least one of the openings (21-1 to 21-4; 22-1 to 22-4) and redirects the gas flow from a first flow direction at the at least one opening (21-1 to 21-4; 22-1 to 22-4) to a second direction, wherein, The angle between the first direction and the second direction is in the range of 80 degrees to 100 degrees, and wherein the main channel (25-1, 25-2) includes at least one of the following: a) an inlet portion including at least one inlet opening fluidly connected to a suction channel from the at least one opening (21-1 to 21-4; 22-1 to 22-4), b) a tube or hose biasing structure (27) arranged downstream of the inlet portion of the main channel and configured to define a bias between the sidewall of the main channel and a tube fluidly connected to the main channel, c) an outlet portion including an outlet opening.

12. A holding system, comprising: The holding device (10) according to any one of the preceding claims, a negative pressure source, and a connection system connecting or configured to connect the holding device (10) and the negative pressure source.

13. An arrangement (1), comprising the holding device (10) according to any one of claims 1 to 11 or the holding system according to claim 12, and an object (O), the object being configured to be held in the holding system to place the object (O) into the device during assembly of the device.

14. A method of assembling a drug delivery device (100) or an electronic module (EM) for a drug delivery device (100), comprising: Providing the holding device (100) according to any one of claims 1 to 12 or the arrangement (1) according to claim 13, placing (240) the object (O) in the holding device (10), Wherein, when the first side (62) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), the object (O) is held within the holding device (10), and Wherein, when the second side (66) faces the at least one opening (21-1 to 21-4; 22-1 to 22-4), the object (O) or another object (O) falls out of the holding device (10), The holding device (10) is used to place (270) the object (O) into the object receiving space within the drug delivery device (100) or the electronic module (EM) or onto the object receiving space.

15. A drug delivery device (100) manufactured by or manufacturable by using the method as claimed in claim 14, comprising: A container receiving portion, wherein the container receiving portion is configured to receive a container (106) containing a drug (Dr, M), and An electronic module (EM), Wherein, the electronic module (EM) is powered by a power source included within or formed by the object (O), Wherein, the object (O) is a button cell, and Wherein, the first surface (64) of the object (O) is arranged to be more proximal compared to the second surface (68) of the object (O), Wherein, the first surface (64) is a flat surface having a first maximum lateral extension or diameter, Wherein, the second surface (68) is a flat surface having a second maximum lateral extension or diameter, Wherein, the first maximum lateral extension or diameter is greater than the second maximum lateral extension or diameter, and Wherein, the first surface (64) has an opposite electrode polarity compared to the second surface (68).

Images