Acne-removing moisturizing lotion and preparation method thereof
By using compound essential oil nanocapsules, bamboo charcoal adsorbing nano silver and other raw materials, the prepared acne-removing moisturizing milk solves the problem of poor stability of existing acne-removing nano lotions, achieving good moisturizing and acne-removing effects, and is suitable for daily skin care products.
Patent Information
- Application Number
- CN202510338084.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-21
- Publication Date
- 2025-06-24
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing acne-removing nano lotion emulsion system only contains lotion particles, which are poorly stable and difficult to be used in daily skin care products.
Use compound essential oil nanocapsules, bamboo charcoal to adsorb nanosilver, collagen, ceramide, hyaluronic acid and other raw materials to prepare acne-removing and moisturizing milk through specific process steps to improve the stability and effect of the emulsion.
It has achieved the stability and effect of acne-removing moisturizing milk, has good moisturizing properties and efficient acne-removing effects, and has no adverse reactions to the skin.
Abstract
Description
Technical Field
[0001] The invention relates to the field of skin care products, and in particular to an anti-acne moisturizing lotion and a preparation method thereof. Background Art
[0002] Nanotechnology is a technology that manipulates atoms and molecules within the spatial scale of 0.1 to 100nm to process materials and give products special functions. As one of the most cutting-edge research hotspots, nanotechnology has penetrated into various industries and fields.
[0003] Acne, also known as pimples, is a chronic inflammation of the sebaceous glands of the hair follicles. The occurrence of acne is related to sebum secretion, excessive angle of the sebaceous gland ducts and infection of Propionibacterium acnes. Acne removal is a comprehensive process that requires regulating oil secretion, improving the keratinization process of the skin, penetrating below the stratum corneum, inhibiting the activity of Propionibacterium acnes, and reducing inflammation to promote the healing of scars. Acne seriously affects beauty and life, so daily skin care cannot be separated from acne products. The acne-removing active ingredients in traditional acne-removing products are mostly retinoic acid drugs, but this type of substance is highly irritating and has a limited range of applications. Nanoemulsion is an alternating dispersion system in which the liquid phase is dispersed in the second phase in the form of droplets. The particle size is between 10 and 200 nm, the system is uniform, and no precipitation or floccules will appear. There have been many reports on acne-removing nanoemulsions generated based on nanotechnology. Chinese patent CN102784085B discloses a composite anti-acne lipid nanoparticle emulsion and its preparation method, wherein a liquid oil phase is prepared from vitex scoparia extract, centella asiatica extract, and tetrahydropiperine, and then the composite anti-acne lipid nanoparticle emulsion is obtained by circulating and homogenizing with distilled water for several times in a high-pressure homogenizer. Chinese patent CN103751231A discloses the use of ginkgo extract nanoliposomes in acne removal and treatment of skin diseases, wherein the ginkgo extract mentioned in the leaves, fruits, outer seed coat, rhizomes, etc. of ginkgo is prepared into nanoliposomes by thin film ultrasound and high-pressure homogenization. The plant nanoemulsion freckle beauty cream disclosed in China's patent CN104606125A is composed of horsetail safflower rapid freckle removal, honeysuckle cypress essential oil killing mites and removing acne and freckle, Niuma vitamin freckle removal, scutellaria baicalensis and angelica anti-aging and anti-wrinkle freckle removal, coix seed and indigo insecticidal willow fungus freckle removal, aloe vera and white tuckahoe acne and scar freckle removal, asparagus and ginkgo leaf color spot and chloasma nanoemulsification freckle beauty cream. It can be seen from the above prior art that the acne nanoemulsion currently used is to nano-crush the active ingredients in the plant to make an aqueous phase, and then mix it with the oil phase to obtain a freckle nanoemulsion. The emulsion system of the nanoemulsion prepared by this method only has emulsion particles, and the stability in dilution and temperature change is poor. The technology is not mature yet and cannot be applied to daily skin care products. Summary of the invention
[0004] In order to solve the above technical problems, the present invention provides an anti-acne moisturizing lotion and a preparation method thereof.
[0005] The object of the present invention can be achieved by the following technical solutions:
[0006] An anti-acne moisturizing milk, comprising the following raw materials in parts by weight: 25-35 parts of compound essential oil nanocapsules, 5-10 parts of bamboo charcoal adsorbed nano-silver, 15-25 parts of lecithin, 1-3 parts of collagen, 1-3 parts of ceramide, 1-3 parts of hyaluronic acid, 1-3 parts of xanthan gum, 1-3 parts of carboxymethyl cellulose, 2-4 parts of isostearoyl lactyl lactate, 1-2 parts of propylene glycol, 1-2 parts of ethylene glycol, 0.5-1 part of phenoxyethanol, 0.5-1 part of methylparaben and 20-30 parts of deionized water;
[0007] The anti-acne moisturizing milk is prepared by the following steps:
[0008] S1: Add isostearoyl lactyl lactate, propylene glycol, ethylene glycol, xanthan gum, carboxymethyl cellulose and lecithin to an oil-phase pot, heat to 75°C - 85°C and stir to mix evenly to obtain an oil phase;
[0009] S2: Add collagen, ceramide, hyaluronic acid, bamboo charcoal adsorbed nano-silver and deionized water to a water-phase pot, heat to 75°C - 85°C, keep warm for 15 min - 30 min, and stir evenly to obtain a water phase;
[0010] S3: Add the oil phase and the water phase to an emulsifying pot, heat to 75°C - 85°C, and homogenize for 20 min - 30 min under the condition of a stirring rate of 20 rpm - 30 rpm;
[0011] S4: Cool the temperature in the emulsifying pot to 35°C, add the compound essential oil nanocapsules, stir and mix evenly, and cool to room temperature to obtain the anti-acne moisturizing milk.
[0012] The compound essential oil nanocapsules are prepared by the following steps:
[0013] A1: Mix aloe essential oil, seabuckthorn fruit extract and mangosteen pericarp extract evenly according to a weight ratio of 5-6:3-4:5-6 to obtain a compound essential oil;
[0014] A2: Gelatin is added to distilled water and stirred to mix evenly to prepare a 5% gelatin solution. The pH of the gelatin solution system is adjusted to 7 - 9 and reserved. Sodium alginate and the compound essential oil are added to distilled water. The weight ratio of sodium alginate, compound essential oil to distilled water is 2:1:33, and then ground to obtain the primary emulsion. Under the condition of high-speed stirring at 1000 r / min, the gelatin solution and the primary emulsion are mixed evenly according to the weight ratio of 0.8 - 1:1, the pH is adjusted to 3 - 5, and stirred continuously for 10 min to obtain a mixed solution. Ice water with the same mass as the mixed solution is added and stirred continuously, cooled to 0 - 10 °C to obtain the diluted mixed solution, and then a 37% formaldehyde solution by mass fraction is added for curing. The mass ratio of the diluted mixed solution to the 37% formaldehyde solution by mass fraction is 5 - 7:1, stirred for 60 min, allowed to stand for precipitation, filtered, washed, and dried to obtain the compound essential oil nanocapsules.
[0015] The bamboo charcoal adsorbed nano - silver is prepared by the following steps:
[0016] B1: Under the condition of 40 - 60 °C, chitosan is added to a 5% acetic acid solution by mass fraction and stirred to dissolve, then bamboo charcoal powder and silver nitrate powder are added and stirred to mix evenly to obtain a mixed solution. The weight ratio of chitosan, 5% acetic acid solution by mass fraction, bamboo charcoal powder and silver nitrate is 5 - 7:45 - 55:15 - 30:1;
[0017] B2: Keep the temperature of the mixed solution at 40 - 60 °C, slowly drop it into an 8.0 - 12.0% polyphosphate solution by mass fraction and stir continuously for 4 h. The weight ratio of the mixed solution to the polyphosphate solution is 1:10. Put it into a centrifuge and centrifuge at 16000 r / min for 30 min, then ultrasonically clean and dry at room temperature for 5 h to obtain the bamboo charcoal adsorbed nano - silver.
[0018] The beneficial effects of the present invention:
[0019] The present invention discloses an acne - removing and moisturizing lotion prepared from compound essential oil nanocapsules, bamboo charcoal adsorbed nano - silver, collagen, ceramide, hyaluronic acid, xanthan gum, carboxymethyl cellulose, sodium isostearoyl lactylate, propylene glycol, ethylene glycol, phenoxyethanol, methylparaben and deionized water as raw materials.
[0020] The compound essential oil nanocapsules encapsulate aloe essential oil, seabuckthorn fruit extract and mangosteen peel extract as active ingredients, which have the functions of moisturizing, antibacterial, anti - inflammatory and repairing damaged cells to achieve the effect of moisturizing and acne - removing. Made into capsules, taking advantage of the characteristic of slow release of active components, the effective period of the acne - removing and moisturizing lotion is extended. A small amount of nano - silver has the functions of broad - spectrum antibacterial, promoting epithelial regeneration and eliminating inflammation on the skin, and its dispersibility is enhanced when adsorbed on bamboo charcoal microspheres, increasing the stability of the whole system. Specific embodiments
[0021] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
[0022] Example 1
[0023] A compound essential oil nanocapsule is prepared by the following steps:
[0024] A1: Mix aloe essential oil, seabuckthorn fruit extract and mangosteen peel extract evenly according to a weight ratio of 5:3:5 to obtain a compound essential oil;
[0025] A2: Add gelatin to distilled water, stir and mix evenly to prepare a gelatin solution with a mass fraction of 5%. Adjust the pH of the gelatin solution system to 7 and set aside. Add sodium alginate and the compound essential oil to distilled water, where the weight ratio of sodium alginate, the compound essential oil and distilled water is 2:1:33, and grind to obtain primary emulsion. Under the condition of high-speed stirring at 1000 r / min, mix the gelatin solution and the primary emulsion evenly according to a weight ratio of 0.8:1, adjust the pH to 3, continuously stir for 10 min to obtain a mixed solution, add ice water with the same mass as the mixed solution and continue to stir, cool down to 0 °C to obtain a diluted mixed solution, add a formaldehyde solution with a mass fraction of 37% for curing, where the mass ratio of the diluted mixed solution to the formaldehyde solution with a mass fraction of 37% is 5:1, stir for 60 min, let it stand for precipitation, filter and wash, and dry to obtain the compound essential oil nanocapsule.
[0026] Example 2
[0027] A compound essential oil nanocapsule is prepared by the following steps:
[0028] A1: Mix aloe essential oil, seabuckthorn fruit extract and mangosteen peel extract evenly according to a weight ratio of 6:3:5 to obtain a compound essential oil;
[0029] A2: Gelatin was added to distilled water and stirred to mix evenly to prepare a 5% gelatin solution. The pH of the gelatin solution system was adjusted to 8 and set aside. Sodium alginate and the compound essential oil were added to distilled water. The weight ratio of sodium alginate, the compound essential oil to distilled water was 2:1:33, and primary emulsion was obtained by grinding. Under the condition of high-speed stirring at 1000 r / min, the gelatin solution and the primary emulsion were mixed evenly according to the weight ratio of 0.9:1, the pH was adjusted to 4, and stirring was continued for 10 min to obtain a mixed solution. Ice water with the same mass as the mixed solution was added and stirring was continued. The temperature was lowered to 5 °C to obtain a diluted mixed solution. A 37% formaldehyde solution by mass was added for curing. The mass ratio of the diluted mixed solution to the 37% formaldehyde solution by mass was 6:1. Stir for 60 min, let stand for precipitation, filter, wash, and dry to obtain the compound essential oil nanocapsules.
[0030] Example 3
[0031] A compound essential oil nanocapsule was prepared by the following steps:
[0032] A1: Aloe essential oil, seabuckthorn fruit element and mangosteen pericarp extract were mixed evenly according to the weight ratio of 5:4:6 to obtain the compound essential oil;
[0033] A2: Gelatin was added to distilled water and stirred to mix evenly to prepare a 5% gelatin solution. The pH of the gelatin solution system was adjusted to 9 and set aside. Sodium alginate and the compound essential oil were added to distilled water. The weight ratio of sodium alginate, the compound essential oil to distilled water was 2:1:33, and primary emulsion was obtained by grinding. Under the condition of high-speed stirring at 1000 r / min, the gelatin solution and the primary emulsion were mixed evenly according to the weight ratio of 1:1, the pH was adjusted to 5, and stirring was continued for 10 min to obtain a mixed solution. Ice water with the same mass as the mixed solution was added and stirring was continued. The temperature was lowered to 10 °C to obtain a diluted mixed solution. A 37% formaldehyde solution by mass was added for curing. The mass ratio of the diluted mixed solution to the 37% formaldehyde solution by mass was 7:1. Stir for 60 min, let stand for precipitation, filter, wash, and dry to obtain the compound essential oil nanocapsules.
[0034] Example 4
[0035] A bamboo charcoal adsorbed nano silver was prepared by the following steps:
[0036] B1: Under the condition of 40 °C, chitosan was added to a 5% acetic acid solution by mass and stirred to dissolve. Bamboo charcoal powder and silver nitrate powder were added and stirred to mix evenly to obtain a mixed solution. The weight ratio of chitosan, the 5% acetic acid solution by mass, bamboo charcoal powder and silver nitrate was 5:45:15:1;
[0037] B2: Maintain the temperature of the mixed solution at 40 °C, slowly drop it into a polyphosphate solution with a mass fraction of 8.0%, continuously stir and react for 4 h. The weight ratio of the mixed solution to the polyphosphate solution is 1:10. Place it in a centrifuge and centrifuge for 30 min at a speed of 16,000 r / min, then perform ultrasonic cleaning and dry at room temperature for 5 h to obtain bamboo charcoal adsorbed nano-silver.
[0038] Example 5
[0039] A kind of bamboo charcoal adsorbed nano-silver is prepared by the following steps:
[0040] B1: Under the condition of 50 °C, add chitosan into a 5% acetic acid solution and stir to dissolve it. Then add bamboo charcoal powder and silver nitrate powder and stir to mix evenly to obtain a mixed solution. The weight ratio of chitosan, 5% acetic acid solution, bamboo charcoal powder and silver nitrate is 5:55:30:1.
[0041] B2: Maintain the temperature of the mixed solution at 50 °C, slowly drop it into a polyphosphate solution with a mass fraction of 10.0%, continuously stir and react for 4 h. The weight ratio of the mixed solution to the polyphosphate solution is 1:10. Place it in a centrifuge and centrifuge for 30 min at a speed of 16,000 r / min, then perform ultrasonic cleaning and dry at room temperature for 5 h to obtain bamboo charcoal adsorbed nano-silver.
[0042] Example 6
[0043] A kind of bamboo charcoal adsorbed nano-silver is prepared by the following steps:
[0044] B1: Under the condition of 60 °C, add chitosan into a 5% acetic acid solution and stir to dissolve it. Then add bamboo charcoal powder and silver nitrate powder and stir to mix evenly to obtain a mixed solution. The weight ratio of chitosan, 5% acetic acid solution, bamboo charcoal powder and silver nitrate is 7:45:15:1.
[0045] B2: Maintain the temperature of the mixed solution at 40 - 60 °C, slowly drop it into a polyphosphate solution with a mass fraction of 12.0%, continuously stir and react for 4 h. The weight ratio of the mixed solution to the polyphosphate solution is 1:10. Place it in a centrifuge and centrifuge for 30 min at a speed of 16,000 r / min, then perform ultrasonic cleaning and dry at room temperature for 5 h to obtain bamboo charcoal adsorbed nano-silver.
[0046] Example 7
[0047] An anti-acne moisturizing lotion, comprising the following raw materials in parts by weight: 25 parts of the compound essential oil nanocapsules obtained in Example 1, 5 parts of the bamboo charcoal adsorbed nano-silver obtained in Example 4, 15 parts of lecithin, 1 part of collagen, 1 part of ceramide, 1 part of hyaluronic acid, 1 part of xanthan gum, 1 part of carboxymethyl cellulose, 2 parts of sodium isostearoyl lactylate, 1 part of propylene glycol, 1 part of ethylene glycol, 0.5 part of phenoxyethanol, 0.5 part of methylparaben, and 20 parts of deionized water;
[0048] The anti-acne moisturizing lotion is prepared by the following steps:
[0049] S1: Add sodium isostearoyl lactylate, propylene glycol, ethylene glycol, xanthan gum, carboxymethyl cellulose, and lecithin to an oil-phase pot, stir and heat to 75 °C, and mix evenly to obtain an oil phase;
[0050] S2: Add collagen, ceramide, hyaluronic acid, bamboo charcoal adsorbed nano-silver, and deionized water to a water-phase pot, heat to 75 °C, keep warm for 15 min, and stir evenly to obtain a water phase;
[0051] S3: Add the oil phase and the water phase to an emulsifying pot, heat to 75 °C, and homogenize for 20 min under the condition of a stirring rate of 20 rpm;
[0052] S4: Cool the temperature in the emulsifying pot to 35 °C, add the compound essential oil nanocapsules, stir and mix evenly, and cool to room temperature to obtain the anti-acne moisturizing lotion.
[0053] Example 8
[0054] An anti-acne moisturizing lotion, comprising the following raw materials in parts by weight: 30 parts of the compound essential oil nanocapsules obtained in Example 2, 8 parts of the bamboo charcoal adsorbed nano-silver obtained in Example 5, 20 parts of lecithin, 2 parts of collagen, 2 parts of ceramide, 2 parts of hyaluronic acid, 2 parts of xanthan gum, 2 parts of carboxymethyl cellulose, 2 parts of sodium isostearoyl lactylate, 1 part of propylene glycol, 1 part of ethylene glycol, 0.5 part of phenoxyethanol, 0.5 part of methylparaben, and 20 parts of deionized water;
[0055] The anti-acne moisturizing lotion is prepared by the following steps:
[0056] S1: Add sodium isostearoyl lactylate, propylene glycol, ethylene glycol, xanthan gum, carboxymethyl cellulose, and lecithin to an oil-phase pot, heat to 75 °C - 85 °C and stir, and mix evenly to obtain an oil phase;
[0057] S2: Add collagen, ceramide, hyaluronic acid, bamboo charcoal adsorbed nano-silver, and deionized water to a water-phase pot, heat to 80 °C, keep warm for 20 min, and stir evenly to obtain a water phase;
[0058] S3: Add the oil phase and the water phase into an emulsifying pan, heat to 80 °C, and homogenize for 25 min under the condition of a stirring rate of 25 rpm;
[0059] S4: Cool the temperature in the emulsifying pan to 35 °C, add the compound essential oil nanocapsules, stir and mix evenly, and cool to room temperature to obtain the anti-acne and moisturizing lotion.
[0060] Example 9
[0061] An anti-acne and moisturizing lotion, comprising the following raw materials in parts by weight: 35 parts of the compound essential oil nanocapsules obtained in Example 3, 10 parts of the bamboo charcoal adsorbed nano-silver obtained in Example 6, 25 parts of lecithin, 3 parts of collagen, 3 parts of ceramide, 3 parts of hyaluronic acid, 3 parts of xanthan gum, 3 parts of carboxymethyl cellulose, 4 parts of sodium isostearoyl lactylate, 2 parts of propylene glycol, 2 parts of ethylene glycol, 1 part of phenoxyethanol, 1 part of methylparaben, and 30 parts of deionized water;
[0062] The anti-acne and moisturizing lotion is prepared by the following steps:
[0063] S1: Add sodium isostearoyl lactylate, propylene glycol, ethylene glycol, xanthan gum, carboxymethyl cellulose, and lecithin into an oil phase pan, heat to 85 °C and stir to mix evenly to obtain an oil phase;
[0064] S2: Add collagen, ceramide, hyaluronic acid, bamboo charcoal adsorbed nano-silver, and deionized water into a water phase pan, heat to 85 °C, keep warm for 30 min, and stir evenly to obtain a water phase;
[0065] S3: Add the oil phase and the water phase into an emulsifying pan, heat to 85 °C, and homogenize for 30 min under the condition of a stirring rate of 30 rpm;
[0066] S4: Cool the temperature in the emulsifying pan to 35 °C, add the compound essential oil nanocapsules, stir and mix evenly, and cool to room temperature to obtain the anti-acne and moisturizing lotion.
[0067] 1: Test of moisturizing performance:
[0068] Test method: Weigh 10 g of each of the formula samples in the following test design table 1 respectively, evenly apply them to a weighing bottle with a 6 cm adhesive tape and a size of 40 * 25, without covering the lid, weigh them (W1), place them in a constant temperature and humidity plant incubator at 30 °C and a relative humidity (RH) of 40% ± 5%, take them out and weigh them every 3 h, and the weighing results are shown in Table 1:
[0069] Table 1
[0070] Sample W1 (g) After 3 h (g) After 6 h (g) After 9 h (g) Example 16 35.000 34.973 34.877 34.741 Example 17 35.000 34.917 34.839 34.704 Example 18 35.000 34.885 34.786 34.683
[0071] Patients of different age groups (20 - 30 years old, 30 - 40 years old) were selected to use the acne - removing and moisturizing lotion prepared in Examples 7 - 9. The cure rate, effective rate and the results of skin adverse reactions after 2 - week treatment are as follows:
[0072] The curative effect results of patients in the 20 - 30 - year - old age group are shown in Table 2:
[0073] Table 2
[0074] Sample Example 7 Example 8 Example 9 Cure rate (%) 65.7 67.3 68.4 Effective rate (%) 100 100 100 Whether there is any adverse reaction to the skin None None None
[0075] The curative effect results of patients in the 30 - 40 - year - old age group are shown in Table 3:
[0076] Table 3
[0077] Sample Example 7 Example 8 Example 9 Cure rate (%) 64.5 66.8 67.6 Effective rate (%) 98.4 99.1 100 Whether there is any adverse reaction to the skin None None None
[0078] It can be seen from Table 1 that the product obtained by the present invention has good moisturizing performance. It can be seen from Table 2 and Table 3 that the cure rate and effective rate of acne of the acne - removing and moisturizing lotion prepared by the present invention are very high, and there are no adverse reactions to the skin.
[0079] The above content is only an example and explanation of the concept of the present invention. Those skilled in the art of this technology can make various modifications or supplements to the described specific embodiments or use similar ways to substitute them. As long as they do not deviate from the concept of the invention or exceed the scope defined by this claim book, they should all belong to the protection scope of the present invention.
Claims
1. An anti-acne moisturizing lotion, characterized in that: The invention comprises the following raw materials in parts by weight: 25 to 35 parts of compound essential oil nanocapsules, 5 to 10 parts of bamboo charcoal adsorbed nanosilver, 15 to 25 parts of lecithin, 1 to 3 parts of collagen, 1 to 3 parts of ceramide, 1 to 3 parts of hyaluronic acid, 1 to 3 parts of xanthan gum, 1 to 3 parts of carboxymethyl cellulose, 2 to 4 parts of sodium isostearyl lactylate, 1 to 2 parts of propylene glycol, 1 to 2 parts of ethylene glycol, 0.5 to 1 part of phenoxyethanol, 0.5 to 1 part of methylparaben and 20 to 30 parts of deionized water; The anti-acne moisturizing lotion is prepared by the following steps: S1: adding sodium isostearyl lactylate, propylene glycol, ethylene glycol, xanthan gum, carboxymethyl cellulose and lecithin into an oil phase pot, heating to 75° C. to 85° C., stirring, and mixing evenly to obtain an oil phase; S2: Add collagen, ceramide, hyaluronic acid, bamboo charcoal adsorbed nanosilver and deionized water into a water phase pot, heat to 75°C to 85°C, keep warm for 15min to 30min, and stir evenly to obtain a water phase; S3: Add the oil phase and the water phase to an emulsifying pot, heat to 75°C to 85°C, and homogenize for 20min to 30min at a stirring rate of 20rpm to 30rpm; S4: The temperature in the emulsifying pot is cooled down to 35°C, compound essential oil nanocapsules, phenoxyethanol and methylparaben are added, stirred and mixed evenly, and cooled to room temperature to obtain the anti-acne moisturizing lotion.
2. The anti-acne moisturizing lotion according to claim 1, characterized in that: The composite essential oil nanocapsule is prepared by the following steps: A1: mixing aloe essential oil, seabuckthorn fruit extract and mangosteen peel extract in a weight ratio of 5-6:3-4:5-6 to obtain a composite essential oil; A2: Gelatin is added to distilled water and stirred to uniformly prepare a gelatin solution with a mass fraction of 5%. The pH of the gelatin solution system is adjusted to 7-9 for standby use. Sodium alginate and compound essential oil are added to distilled water, wherein the weight ratio of sodium alginate, compound essential oil and distilled water is 2:1:
33. Colostrum is obtained by grinding. Under the condition of high-speed stirring at 1000r / min, the gelatin solution and colostrum are uniformly mixed in a weight ratio of 0.8-1:
1. The pH is adjusted to 3-5. Stirring is continued for 10 minutes to obtain a mixed solution. Ice water of the same mass as the mixed solution is added and continued to be stirred. The mixture is cooled to 0-10°C to obtain a diluted mixed solution. A formaldehyde solution with a mass fraction of 37% is added for solidification, wherein the mass ratio of the diluted mixed solution to the formaldehyde solution with a mass fraction of 37% is 5-7:
1. Stirring is performed for 60 minutes. The mixture is allowed to stand for precipitation. The mixture is filtered, washed and dried to obtain the compound essential oil nanocapsules.
3. The anti-acne moisturizing lotion according to claim 1, characterized in that: The bamboo charcoal adsorbing nanosilver is prepared by the following steps: B1: at 40-60° C., chitosan was added to a 5% acetic acid solution and stirred to dissolve, bamboo charcoal powder and silver nitrate powder were added and stirred to mix uniformly to obtain a mixed solution, wherein the weight ratio of chitosan, 5% acetic acid solution, bamboo charcoal powder and silver nitrate was 5-7:45-55:15-30:1; B2: Keep the temperature of the mixed solution at 40-60°C, slowly add it dropwise into the polyphosphate solution with a mass fraction of 8.0-12.0% and keep stirring for 4 hours. The weight ratio of the mixed solution to the polyphosphate solution is 1:
10. Put it into a centrifuge and centrifuge it at 16000r / min for 30 minutes. After ultrasonic cleaning, dry it at room temperature for 5 hours to obtain bamboo charcoal adsorbed with nano-silver.
4. The method for preparing an anti-acne moisturizing lotion according to claim 1, characterized in that: The specific preparation steps are as follows: S1: adding sodium isostearyl lactylate, propylene glycol, ethylene glycol, xanthan gum, carboxymethyl cellulose and lecithin into an oil phase pot, heating to 75° C. to 85° C., stirring, and mixing evenly to obtain an oil phase; S2: Add collagen, ceramide, hyaluronic acid, bamboo charcoal adsorbed nanosilver and deionized water into a water phase pot, heat to 75°C to 85°C, keep warm for 15min to 30min, and stir evenly to obtain a water phase; S3: Add the oil phase and the water phase to an emulsifying pot, heat to 75°C to 85°C, and homogenize for 20min to 30min at a stirring rate of 20rpm to 30rpm; S4: The temperature in the emulsifying pot is cooled to 35°C, and the compound essential oil nanocapsules are added, stirred and mixed evenly, and cooled to room temperature to obtain the anti-acne moisturizing lotion.
Citation Information
Patent Citations
Composite acne removing lipid nanoparticle emulsion and preparation method thereof
CN102784085B
Application of gingko extract nanometer liposome in acne removing and dermatosis treatment
CN103751231A
Plant nano-emulsion anti-freckle cosmetic cream
CN104606125A
