Slurry melting device and slurry melting method
By combining microwave heating and electrical heating in the slurry device, the problems of uneven and low efficiency of plasma melting in the prior art are solved, and a more efficient and uniform plasma heating process is achieved.
Patent Information
- Application Number
- CN202510385122.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-28
- Publication Date
- 2025-06-24
AI Technical Summary
The existing dry slurry slurry is heated by hot air, resulting in uneven melting of plasma bags and low efficiency.
The combination of microwave heating and traditional electric heating is used to quickly heat up in the initial stage of microwave heating, and then continue heating by electric heating. The temperature is detected by the thermometer to switch to achieve rapid heating and avoid plasma denaturation.
It improves the efficiency and uniformity of plasma heating, and avoids plasma degeneration or degradation caused by excessive microwave heating.
Smart Images
Figure CN120189565A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of blood products, and particularly relates to a plasma thawing device and a plasma thawing method. Background Art
[0002] Plasma is the extracellular matrix of blood. The composition of plasma includes proteins, lipids, inorganic salts, sugars, amino acids, metabolic wastes, and a large amount of water. Based on blood, after removing blood cells and undergoing purification and other treatment steps, the product plasma is obtained. Plasma needs to be frozen during storage and thawed when needed. The use of blood products first involves thawing the plasma. Whether it is fresh frozen plasma or ordinary frozen plasma, it is stored at a temperature below -20°C. When using frozen plasma, it needs to be thawed at a temperature of 30°C - 37°C until the plasma is completely melted into a liquid. If the temperature is too high, it will damage the coagulation factors and proteins contained in the plasma. At the same time, if the thawing temperature is lower than 30°C, not only will the thawing time of the plasma be prolonged, but also fibrinogen in the plasma may precipitate.
[0003] A plasma thawing machine, also known as a constant temperature thawing instrument, is used to thaw frozen plasma and heat it to the required temperature. Existing plasma thawing machines include wet plasma thawing machines and dry plasma thawing machines. The wet plasma thawing machine heats the plasma bag through a water bath. During use, the label on the surface of the plasma bag is easily soaked and damaged by water, and the water is easily contaminated. After taking the plasma bag out of the water, a large amount of water droplets adhere to the surface of the plasma bag, and a rag or the like is needed to dry the water droplets on the surface of the plasma bag, which requires a high level of aseptic operation environment.
[0004] Using a dry plasma thawing machine to heat the plasma bag through a hot air stream can avoid the problem of water droplet contamination. However, the hot air stream blowing of the dry plasma thawing machine acts on the surface of the plasma bag, easily resulting in uneven thawing of the plasma bag and low thawing efficiency. Summary of the Invention
[0005] In view of the problem that the existing dry plasma thawing machine uses hot air heating, which only acts on the surface of the plasma bag, resulting in uneven plasma thawing and low efficiency, the present invention provides a plasma thawing device.
[0006] To solve the above problems, the technical solution adopted by the present invention is a plasma thawing device, which includes a box body. A thawing cavity is arranged inside the box body, and a temperature detector is arranged at the top of the thawing cavity; a thawing rack is arranged in the thawing cavity, and a plurality of thawing mesh screens for accommodating plasma bags are arranged on the thawing rack; a microwave heating mechanism is arranged at the rear end of the thawing cavity, and the output end of the microwave heating mechanism is fixedly connected to a microwave conductor arranged on the inner side of the rear end of the thawing cavity; electric heating mechanisms are arranged on both sides of the thawing cavity, and a flow guide member is detachably arranged at the output end of the electric heating mechanism, and the flow guide member is arranged corresponding to the thawing mesh screen. This device adopts a combination of microwave heating and traditional electric heating. In the initial stage of heating, the plasma in the plasma bag can be quickly heated up by the microwave heating mechanism, and then continuously heated by the electric heating mechanism. Through the combined action of the two heating methods and using the temperature detector to detect the temperature for switching, on the one hand, rapid heating is achieved, and on the other hand, the risk of plasma denaturation caused by excessive plasma temperature rise due to continuous microwave heating can be avoided, greatly improving the efficiency of plasma heating.
[0007] As a preferred implementation of the plasma thawing device, a turntable is rotatably arranged at the bottom of the thawing cavity through a rotating mechanism. The turntable is connected to the rotating mechanism through a magnetic coupling mechanism, and the thawing rack is detachably arranged on the turntable through a limiting mechanism. Driving the thawing rack to rotate by the turntable enables the plasma bags to be evenly heated during the thawing process, avoiding the situation of uneven local heating, further improving the uniformity of plasma heating, and helping to ensure the quality of plasma. At the same time, the thawing rack is detachably arranged, which is convenient for cleaning and maintenance of the thawing rack after the thawing work is completed.
[0008] As a preferred implementation of the plasma thawing device, the magnetic coupling mechanism includes a driven magnet arranged at the bottom of the turntable and a driving magnet arranged at the output end of the rotating mechanism. The driving magnet and the driven magnet are arranged corresponding to each other; a driven groove for accommodating the driven magnet is arranged on the inner side of the thawing cavity, and a driven limiting block extends outward from the center of the driven groove. A driven cover body is arranged outside the driven magnet, and a driven limiting groove corresponding to the driven limiting block is arranged at the center of the driven cover body; a driving groove for accommodating the driving magnet is arranged on the outer side of the thawing cavity, and a driving limiting block extends outward from the center of the driving groove. A driving cover body is arranged outside the driving magnet, and a driving limiting groove corresponding to the driving limiting block is arranged at the center of the driving cover body. The magnetic coupling mechanism realizes non-contact transmission, ensures the integrity and heat preservation of the thawing cavity, improves the reliability and service life of the device. At the same time, the matching design of the limiting block and the limiting groove ensures the precise alignment of the driving magnet and the driven magnet during rotation, guaranteeing the stability of transmission, so that the thawing rack can rotate smoothly and continuously, improving the uniformity of plasma heating.
[0009] As a preferred implementation of a plasma thawing device, the rotation mechanism includes a rotation motor disposed outside the plasma thawing chamber, and the output end of the rotation motor is drivingly connected to the active magnet of the magnetic coupling mechanism through a coupling. The rotation motor provides a stable power source for the rotation of the turntable, facilitating the control of the rotation speed of the plasma thawing rack to achieve the best effect of uniform plasma heating; the use of the coupling effectively buffers the impact force during the start-up and operation of the motor, protects the motor and the magnetic coupling mechanism, and extends the overall service life of the equipment.
[0010] As a preferred implementation of a plasma thawing device, the limiting mechanism includes a limiting opening disposed at the top of the turntable, the inner wall of the limiting opening is covered with friction blocks, and a limiting post is provided at the bottom of the plasma thawing rack, and the limiting post is snapped into the limiting opening. The design of the limiting mechanism makes the connection between the plasma thawing rack and the turntable simple and stable, and can ensure that the plasma thawing rack follows the rotation without displacement during the rotation of the turntable. The setting of the friction blocks further enhances the stability of the connection, preventing the plasma thawing rack from detaching from the turntable due to vibration or inertial force during the rotation process, and ensuring the smooth progress of the plasma thawing work.
[0011] As a preferred implementation of a plasma thawing device, a plurality of card slots are provided on the plasma thawing rack, and a connection frame is provided on the outer side of the plasma thawing mesh, and connection columns are correspondingly provided on both sides of the connection frame, and the connection columns can be snap-fitted with the card slots; a tray is further provided below the plasma thawing mesh, and the tray is snap-fitted with the card slots through the connection columns correspondingly provided on both sides. The snap-fitting of the card slots and the connection columns facilitates the installation and disassembly of the plasma thawing mesh and the tray, and is convenient for replacing plasma thawing meshes or trays of different specifications according to actual plasma thawing requirements. At the same time, it ensures the stable installation of the plasma thawing mesh and the tray on the plasma thawing rack, so that the plasma bag can remain stable during the plasma thawing process, which is beneficial to uniform heating.
[0012] As a preferred implementation of a plasma thawing device, the microwave heating mechanism includes a microwave generator disposed at the rear side of the plasma thawing chamber, a waveguide is provided at the output end of the microwave generator, a waveguide hole is provided at the output end of the waveguide, the waveguide hole is located at the center position of the rear end of the plasma thawing chamber, and a ceramic fixing seat for fixing one end of the microwave conductor is provided at the waveguide hole. The microwave heating mechanism can quickly increase the plasma temperature at the initial stage of heating and improve the plasma thawing efficiency. The ceramic fixing seat has good insulation and high temperature resistance performance, which can not only ensure the stable installation of the microwave conductor, but also prevent microwave leakage and ensure the safe operation of the equipment.
[0013] As a preferred implementation of the plasma thawing device, the electric heating mechanism includes heaters arranged on the outer sides of both ends of the thawing cavity. As a preferred implementation of the plasma thawing device, the microwave conductor includes a microwave guide pin fixedly arranged inside a ceramic fixing base, and a microwave guide strip is fixedly arranged at the top of the microwave guide pin; the microwave guide strip is in a vortex structure, and the microwave guide strip extends outward in a spiral shape from the center position at the rear end of the thawing cavity. The microwave guide strip with a vortex structure increases the acting area of the microwave, enabling the microwave to be more evenly distributed in the thawing cavity, further improving the uniformity of plasma heating, avoiding uneven plasma heating or denaturation caused by excessive local microwave energy, and improving the thawing quality.
[0014] And an air blower is arranged at the output end of the heater, and the output end of the air blower is arranged corresponding to the air holes on both sides of the thawing cavity, and a flow guiding member is detachably arranged at the air holes.
[0015] On the other hand, the present invention also provides a plasma thawing method, which uses the above-mentioned plasma thawing device, and the method includes the following steps: S1. According to the specification model of the plasma bag, preset the heating-up time, and determine the initial target temperature, the final target temperature and the heat preservation time; S2. The synchronous control module controls the microwave heating mechanism and the electric heating mechanism to heat the thawing cavity synchronously according to the temperature value in the thawing cavity collected by the temperature detector, so that the temperature in the thawing cavity reaches the initial target temperature; S3. After the initial determination module determines that the temperature in the thawing cavity reaches the initial target temperature according to the temperature value in the thawing cavity collected by the temperature detector, it controls the microwave heating mechanism to turn off and controls the electric heating mechanism to continue heating the thawing cavity; S4. The final determination module determines the heating rate of the electric heating mechanism according to the absolute error value between the current temperature in the thawing cavity and the final target temperature and the absolute error value between the current time and the preset heating-up time according to the temperature value in the thawing cavity collected by the temperature detector; S5. The independent control module controls the output duty ratio of the electric heating mechanism according to the heating rate, and controls the electric heating mechanism to heat the thawing cavity at the heating rate, so that the temperature in the thawing cavity reaches the final target temperature; S6. Within the range of the heat preservation time, when the absolute value of the error between the temperature value in the thawing cavity and the final target temperature is greater than or equal to the preset switching threshold, the heat preservation module controls the electric heating mechanism to maintain the final target temperature in the thawing cavity according to the heat preservation time.
[0016] As can be seen from the above technical solutions, the beneficial effects of the present invention are as follows: By using a combination of a microwave heating mechanism and an electric heating mechanism, the temperature in the plasma melting chamber can be quickly raised to the initial target temperature. After reaching the initial target temperature, the electric heating mechanism can continue to raise the temperature in the plasma melting chamber to the final target temperature. By directly applying microwave radiation to the plasma, it can heat the plasma both inside and outside simultaneously. While quickly reaching the temperature required for plasma melting using microwaves, it can avoid plasma denaturation or degradation caused by excessive microwave heating. Through the setting of the microwave conductor, the microwave conductor can evenly radiate the microwaves generated by the microwave heating mechanism into the plasma melting chamber, making the microwave distribution in the plasma melting chamber more uniform and reducing the heating cold spots in the plasma melting chamber. And the rotating mechanism can drive the plasma melting rack on the turntable to rotate uniformly relative to the plasma melting chamber. While making the plasma heat more evenly, it can achieve the effect of shaking the plasma bag, be able to shake the plasma evenly, and prevent blood stratification. By setting a flow guiding member at the output end of the electric heating mechanism, the flow guiding member can make the hot air flow through both sides of the plasma bag. While heating the plasma bag, it can dry the surface of the plasma bag, avoid wiping and contaminating the surface of the plasma bag, and ensure the integrity of the label on the surface of the plasma bag. Through the setting of the magnetic coupling mechanism, while the rotating mechanism drives the turntable to rotate uniformly relative to the plasma melting chamber through the magnetic coupling mechanism, it can seal the plasma melting chamber. In this way, microwave radiation leakage will not occur during the plasma melting process, and it will not cause radiation damage to the human body during use, and it will not cause bacterial contamination of the plasma bag due to the sealing problem of the plasma melting chamber. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] In order to more clearly illustrate the technical solutions of the present invention, the drawings required for description will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.
[0018] Figure 1 Structural schematic of the specific embodiment of the present invention Figure 1 。
[0019] Figure 2 Structural schematic diagram of the plasma melting chamber in the specific embodiment of the present invention.
[0020] Figure 3 Structural schematic of the specific embodiment of the present invention Figure 2 。
[0021] Figure 4 Structural schematic diagram of the limiting mechanism in the specific embodiment of the present invention.
[0022] Figure 5 Structural schematic diagram of the microwave conductor in the specific embodiment of the present invention.
[0023] Figure 6 Cross-section of the specific implementation mode of the present invention Figure 1 。
[0024] Figure 7 Cross-section of the specific implementation mode of the present invention Figure 2 。
[0025] Figure 8 Schematic structural diagram of the rotation mechanism in the specific implementation mode of the present invention.
[0026] Figure 9 Schematic structural diagram of the magnetic coupling mechanism in the specific implementation mode of the present invention.
[0027] Figure 10 Schematic structural diagram of the control module in the specific implementation mode of the present invention.
[0028] Main reference numeral description 1. Box body, 2. Melting cavity, 3. Magnetic coupling mechanism, 4. Rotation mechanism, 5. Limiting mechanism, 6. Melting rack, 7. Microwave heating mechanism, 8. Microwave conductor, 9. Electric heating mechanism, 10. Flow guiding member, 11. Synchronous control module, 12. Initial determination module, 13. Final determination module, 14. Independent control module, 15. Heat preservation module, 21. Hinge, 22. Door body, 23. Temperature detector, 24. Turntable, 31. Driven magnet, 32. Driving magnet, 311. Driven groove, 312. Driven limiting block, 313. Driven cover body, 314. Driven limiting groove, 321. Driving groove, 322. Driving limiting block, 323. Driving cover body, 324. Driving limiting groove, 41. Rotation motor, 42. Coupling, 43. Motor seat, 44. Motor column, 51. Limiting port, 52. Limiting column, 61. Melting mesh, 62. Card slot, 63. Connection frame, 64. Connection column, 71. Microwave generator, 72. Wave guide, 73. Wave guide hole, 74. Ceramic fixing seat, 81. Microwave guide pin, 82. Microwave guide strip, 91. Heater, 92. Hair dryer, 101. Plug-in ring, 102. Flow guiding piece. Specific implementation mode
[0029] To make the objectives, features, and advantages of the present invention more obvious and understandable, the technical solutions in the present invention will be clearly and completely described below in conjunction with the drawings in the specific embodiments of the present invention. Obviously, the embodiments described below are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments in this patent, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the scope of protection of this patent.
[0030] Embodiment 1 Such as Figure 1, 2 As shown in Figures 3, 6 and 7, a melting device comprises a box body 1, wherein a melting chamber 2 is arranged inside the box body 1, and a door body 22 is rotatably arranged at the front of the melting chamber 2 via a hinge 21, and the melting chamber 2 can be sealed by the door body 22, so that a sealed environment is formed in the melting chamber 2 to prevent microwave leakage, and a window can be arranged on the door body 22, so that the melting situation in the melting chamber 2 can be observed through the window.
[0031] A temperature sensor 23 is provided on the outer side of the top of the melt chamber 2 (the melt chamber is a closed shell, and the outer side of the top is defined as the outside of the shell wall and the inside of the shell wall, the same below). The temperature sensor 23 can ensure real-time online temperature measurement in a true sense, and can effectively monitor the temperature changes in the melt chamber 2 and the plasma bag. The temperature sensor 23 can adopt a platinum resistance thermometer PT100, a thermocouple, an NTC temperature sensor, etc.
[0032] A turntable 24 is rotatably arranged on the inner side of the bottom of the molten plasma chamber 2, and the turntable 24 is transmission-connected to a rotating mechanism 4 arranged on the outer side of the bottom of the molten plasma chamber 2 through a magnetic coupling mechanism 3; through the arrangement of the magnetic coupling mechanism 3, the power of the external rotating mechanism 4 can be transmitted to the turntable 24 in the molten plasma chamber 2 without contact, and the rotating mechanism 4 can seal the molten plasma chamber 2 while driving the turntable 24 to rotate at a uniform speed relative to the molten plasma chamber 2 through the magnetic coupling mechanism 3, so that no microwave radiation leakage will occur during the molten plasma process, and no radiation damage will be caused to the human body during use, and no bacterial contamination of the plasma bag will occur due to the sealing problem of the molten plasma chamber 2, and the rotating mechanism 4 can drive the molten plasma frame 6 on the turntable 24 to rotate at a uniform speed relative to the molten plasma chamber 2, so that the plasma can be heated more evenly and the effect of shaking the plasma bag can be achieved, so that the plasma can be shaken evenly to prevent blood stratification.
[0033] like Figure 8 As shown, the rotating mechanism 4 includes a rotating motor 41 arranged outside the melting chamber 2, a motor seat 43 is arranged on the rotating motor 41, and the motor seat 43 is fixedly connected to the outside of the melting chamber 2 through a motor column 44, the rotating motor 41 can be fixed to the outside of the bottom of the melting chamber 2 by using external bolts and the motor column 44, and is installed in a detachable manner by bolt connection, the rotating motor 41 is located outside the melting chamber 2, and the output end of the rotating motor 41 is transmission-connected with the active magnet 32 of the magnetic coupling mechanism 3 through a coupling 42, the output end of the rotating motor 41 is fixedly connected to one end of the coupling 42, and the other end of the coupling 42 is fixedly connected to an active cover 323 arranged outside the active magnet 32, so that the rotating motor 41 can drive the turntable 24 to rotate at a uniform speed in the melting chamber 2 through the magnetic coupling mechanism 3, which can prevent the melting rack 6 located on the turntable 24 from having a heating cold spot, so that the plasma bag on the melting rack 6 is heated more evenly during the heating process.
[0034] As Figure 9 shown, the magnetic coupling mechanism 3 includes a driven magnet 31 disposed at the bottom of the turntable 24 and a driving magnet 32 disposed at the output end of the rotating mechanism 4. The driving magnet 32 and the driven magnet 31 are arranged corresponding to each other and coaxially, which can improve the stability of the magnetic coupling mechanism 3. Specifically, a driven groove 311 for accommodating the installation of the driven magnet 31 is provided inside the melting cavity 2, and a driven limiting block 312 extends outward from the axis of the driven groove 311; a driven cover 313 is arranged outside the driven magnet 31, and a driven limiting groove 314 corresponding to the driven limiting block 312 is arranged at the axis of the driven cover 313. The driven limiting block 312 can support the driven cover 313, so that the driven magnet 31 can rotate inside the melting cavity 2. The driving magnet 32 can drive the driven magnet 31 and the driven cover 313 to rotate relative to the driven groove 311 and the driven limiting block 312, and the driven limiting block 312 can be inserted into the driven limiting groove 314 to limit the circumferential position of the driven magnet 31 and the driven cover 313; an active groove 321 for accommodating the installation of the driving magnet 32 is provided outside the melting cavity 2, and an active limiting block 322 extends outward from the axis of the active groove 321; an active cover 323 is arranged outside the driving magnet 32, and an active limiting groove 324 corresponding to the active limiting block 322 is arranged at the axis of the active cover 323. The active limiting block 322 can support the active cover 323, so that the driving magnet 32 can rotate outside the melting cavity 2. The rotating mechanism 4 can drive the driving magnet 32 and the active cover 323 to rotate relative to the active groove 321 and the active limiting block 322, and the active limiting block 322 can be inserted into the active limiting groove 324 to limit the circumferential position of the driving magnet 32 and the active cover 323.
[0035] In the above structure, in order to further reduce the resistance generated during rotation, bearings can be provided between the driven cover 313 and the driven limiting block 312 and between the active cover 323 and the active limiting block 322. The bearings can reduce the resistance during rotation and reduce power loss. A gap is maintained between the driven cover 313 and the driven groove 311, and a gap is also maintained between the active cover 323 and the active groove 321. Thus, a rotating space will be formed between the driven cover 313 and the driven groove 311, and between the active cover 323 and the active groove 321, thereby reducing friction.
[0036] Furthermore, the driven magnet 31 and the driving magnet 32 are of opposite polarity to each other, with high magnetic coupling efficiency, which can ensure the stability of the rotation of the turntable 24; and the driven magnet 31 and the driving magnet 32 have the same length, height, and thickness.
[0037] At the top of the turntable 24, a plasma melting rack 6 is detachably arranged through a limiting mechanism 5. By using the turntable 24 and the plasma melting rack 6 in cooperation, a three-dimensional turntable 24 structure can be formed, which not only increases the plasma melting area, but also enables the plasma bags to perform three-dimensional rotational motion in the plasma melting cavity 2, ensuring the uniformity of plasma melting. A number of plasma melting mesh screens 61 for placing plasma bags are arranged in an array along the height direction of the plasma melting cavity 2 on the plasma melting rack 6; the setting of the plasma melting mesh screens 61 can accommodate the placement of plasma bags without affecting the airflow passing through both sides of the plasma bags.
[0038] As Figure 4 shown, the limiting mechanism 5 includes a limiting port 51 arranged at the top of the turntable 24 and a limiting post 52 fixedly arranged at the bottom of the plasma melting rack 6. The inner wall of the limiting port 51 is covered with a friction block, which can increase the friction force and enable the limiting post 52 to be stably arranged in the limiting port 51. The limiting post 52 can be inserted into the limiting port 51 to limit the circumferential position of the limiting post 52, and the turntable 24 can drive the plasma melting rack 6 to rotate uniformly relative to the plasma melting cavity 2. In this way, while the turntable 24 drives the plasma melting rack 6 to rotate, the plasma melting rack 6 can be prevented from shaking on the turntable 24.
[0039] A microwave heating mechanism 7 is arranged on the outer side of the rear part of the plasma melting cavity 2, and the output end of the microwave heating mechanism 7 is fixedly connected to a microwave conductor 8 arranged on the inner side of the rear part of the plasma melting cavity 2. Through the setting of the microwave conductor 8, the microwave generated by the microwave heating mechanism 7 can be evenly radiated into the plasma melting cavity 2, making the microwave distribution in the plasma melting cavity 2 more uniform and reducing the heating cold spots in the plasma melting cavity 2. Electric heating mechanisms 9 are also arranged on the outer sides of both ends of the plasma melting cavity 2, and a flow guide member 10 is detachably arranged at the output end of the electric heating mechanism 9; the flow guide member 10 is arranged corresponding to the plasma melting mesh screens 61, and the flow guide member 10 can buffer and adjust the direction of the airflow, enabling the airflow to pass through both sides of the plasma bags. By arranging the flow guide member 10 at the output end of the electric heating mechanism 9, the flow guide member 10 can make the hot airflow pass through both sides of the plasma bags, drying the surface of the plasma bags while heating the plasma bags, avoiding wiping and contaminating the surface of the plasma bags, and ensuring the integrity of the labels on the surface of the plasma bags.
[0040] The microwave heating mechanism 7 includes a microwave generator 71 arranged on the outer side of the rear part of the plasma melting cavity 2, and a waveguide 72 is arranged at the output end of the microwave generator 71; a waveguide hole 73 is arranged at the output end of the waveguide 72. The waveguide hole 73 is located at the center of the rear part of the plasma melting cavity 2, and a ceramic fixing seat 74 for fixing one end of the microwave conductor 8 is arranged at the waveguide hole 73. The ceramic fixing seat 74 can play an insulating role. By arranging the ceramic fixing seat 74 between the microwave conductor 8 and the waveguide 72, the microwave conductor 8 and the waveguide 72 can be isolated to prevent charge accumulation and generate high voltage, avoiding the occurrence of microwave arcing. As Figure 5As shown, the microwave conductor 8 includes a microwave guide pin 81 fixedly arranged inside the ceramic fixing base 74, and a microwave guide strip 82 for forming a specified microwave is fixedly arranged at the top of the microwave guide pin 81; in the present invention, the microwave guide pin 81 and the microwave guide strip 82 are designed as an integrally formed structure, and both the microwave guide pin 81 and the microwave guide strip 82 are made of the same metal material. The microwave guide strip 82 is in a vortex structure, and the microwave guide strip 82 extends outward in a spiral shape from the central position at the rear of the melting cavity 2. The microwave guide strip 82 arranged in a vortex structure can uniformly radiate the microwave generated by the microwave heating mechanism 7 into the melting cavity 2, making the microwave distribution in the melting cavity 2 more uniform, reducing the heating cold spots in the melting cavity 2, and making the plasma heat more evenly. The microwave guide pin 81 guides the microwave from the waveguide 72 to the microwave guide strip 82, and the microwave guide strip 82 uniformly radiates the microwave into the melting cavity 2. One end of the microwave guide pin 81 is located at the vortex center of the microwave guide strip 82, and the microwave guide pin 81 is inserted into the ceramic fixing base 74 inside the waveguide 72.
[0041] In the present invention, since the microwave guide strip 82 needs to extend into the melting cavity 2, in order to prevent the microwave guide strip 82 from contacting the melting cavity 2, ceramic insulating plates can be arranged on both sides of the microwave guide strip 82. Slots can be opened on one end of the ceramic insulating plate, and the slots are arranged corresponding to the microwave guide strip 82. By placing the microwave guide strip 82 in the ceramic insulating plate with slots at one end and covering the microwave guide strip 82 with the ceramic insulating plate at the other end, a good insulating effect can be achieved while fixing the position of the microwave guide strip 82.
[0042] The electric heating mechanism 9 includes heaters 91 arranged on the outer sides of both ends of the melting cavity 2. The heaters 91 can be arranged in parallel according to needs, and a blower 92 is arranged at the output end of the heaters 91. In this way, the air blown by the blower 92 can be heated by the heaters 91. The output end of the blower 92 is arranged corresponding to the air holes at both ends of the melting cavity 2. The hot air flow heated by the heaters 91 can be blown into the melting cavity 2 through the air holes, achieving the effect of heating the melting cavity 2; and a flow guide member 10 can be arranged in a pluggable manner at the air holes. The flow guide member 10 can make the hot air flow pass through both sides of the plasma bag. While heating the plasma bag, the surface of the plasma bag can be dried, avoiding wiping and contaminating the surface of the plasma bag, and ensuring the integrity of the label on the surface of the plasma bag. Specifically, the flow guide member 10 includes a plugging ring 101 that can be arranged in a pluggable manner at the output end of the electric heating mechanism 9, and a flow guide piece is arranged at the end of the plugging ring 101 facing the melting mesh 61. Flow guide members 10 of different specifications and models can be provided. Through the arrangement of the plugging ring 101, the flow guide member 10 can be quickly installed and disassembled. In this way, the flow guide member 10 can be replaced according to the specifications and models of the plasma bag.
[0043] In the present invention, the air hole is designed with a circular structure, and the plug-in ring 101 is arranged in an annular structure. When the flow guide member 10 is installed on the air hole, the air hole is coaxially arranged with the plug-in ring 101. In this way, when the hot air flow, the plug-in ring 101 will communicate with the air hole to form a gas passage through which the hot air can flow normally, and the hot air is blown out through the flow guide vane; the flow guide vane is correspondingly arranged at the same side end of the plug-in ring 101, and the flow guide vane can buffer and adjust the direction of the air flow, so that the air flow flows through both sides of the plasma bag. The heated air flow flows through the air inlet hole to the flow guide vane, and the flow guide vane can buffer and adjust the direction of the hot air flow, so that the hot air flow blows to both sides of the plasma bag, and the surface of the plasma bag can be dried while heating the plasma bag.
[0044] In the present invention, by the combined use of the microwave heating mechanism 7 and the electric heating mechanism 9, the temperature in the plasma melting chamber 2 can be quickly raised to the initial target temperature. After reaching the initial target temperature, the temperature in the plasma melting chamber 2 can reach the final target temperature through the electric heating mechanism 9. By directly acting on the plasma through microwave radiation, the plasma can be heated both inside and outside at the same time. While quickly reaching the temperature required for plasma melting by microwave, it can avoid plasma denaturation or degradation caused by excessive microwave heating.
[0045] A number of card slots 62 are provided on the plasma melting rack 6, and a connecting frame 63 is arranged on the outer side of the plasma melting mesh 61; connecting columns 64 are correspondingly arranged on both sides of the connecting frame 63, and the connecting columns 64 can be detachably connected with the card slots 62. The connecting columns 64 are slidably connected with the card slots 62. In this way, the connecting columns 64 can be embedded in the card slots 62, and the card slots 62 can limit the connecting columns 64, so as to prevent the connecting columns 64 from disengaging from the card slots 62. A tray is correspondingly arranged below the plasma melting mesh 61, and the tray can be detachably connected with the card slots 62 through the connecting columns 64 correspondingly arranged on both sides. In this way, the tray can be disassembled according to needs, which is convenient for cleaning and replacing the tray.
[0046] When the flexible plasma melting device is in use, first perform presetting. The initial target temperature is preset to 30 °C, the final target temperature is preset to 37 °C, the switching threshold is preset to 1 °C, the heat preservation time is preset to 30 minutes, and the protein denaturation temperature is 60 - 70 °C. Set 30 °C as the temperature point for switching from microwave heating to electric heating, which has a large temperature difference from the final target temperature of heating 37 °C and the protein denaturation temperature, and can avoid the denaturation of proteins in the plasma during heating to the greatest extent.
[0047] Then, according to the temperature value in the plasma melting chamber 2 collected by the temperature detector 23, the synchronous control module 11 controls the microwave heating mechanism 7 and the electric heating mechanism 9 to heat the plasma melting chamber 2 synchronously, so that the temperature in the plasma melting chamber 2 can be quickly raised to the initial target temperature (i.e., 30 °C).
[0048] To avoid plasma denaturation or degradation caused by excessive microwave heating, after the temperature in the plasma melting chamber 2 reaches 30°C, the initial determination module 12 controls the microwave heating mechanism 7 to turn off and controls the electric heating mechanism 9 to continue heating the plasma melting chamber 2. After the final determination module 13 determines the heating rate of the electric heating mechanism 9, the independent control module 14 controls the electric heating mechanism 9 to enable the temperature in the plasma melting chamber 2 to rise flexibly and reach the final target temperature (i.e., 37°C).
[0049] Since a switching threshold is preset, when the temperature value in the plasma melting chamber 2 drops from 37°C to 36°C, the absolute value of the error between the final target temperature and the current temperature in the plasma melting chamber 2 is equal to the preset switching threshold (i.e., 1°C), and the heat preservation module 15 continues to control the electric heating mechanism 9 to heat up, so that the temperature in the plasma melting chamber 2 can be continuously maintained at the final target temperature within the heat preservation time.
[0050] Embodiment 2 Based on Embodiment 1, this embodiment further provides a flexible plasma melting method, including the following steps: S1. According to the specification model of the plasma bag, preset the heating-up time, and determine the initial target temperature, the final target temperature and the heat preservation time; since when melting plasma, its melting temperature cannot exceed 37°C, if the temperature is too high, it will damage the coagulation factors and proteins contained in the plasma. If the melting temperature is lower than 30°C, not only will the plasma melting time be prolonged, but also fibrinogen in the plasma may precipitate.
[0051] Therefore, in the present invention, the initial target temperature is between 30°C and 36°C, the final target temperature is higher than the initial target temperature but does not exceed 37°C, and the heat preservation time can be specifically set according to the actual situation, and this application does not limit it.
[0052] In the present invention, a controller is provided inside the box body 1, as Figure 10 shown, the controller is integrally provided with a synchronous control module 11, an initial determination module 12, a final determination module 13, an independent control module 14 and a heat preservation module 15; a display screen is provided on the top of the box body 1, and the display screen can intuitively display the temperature inside the plasma melting chamber 2; the controller is electrically connected to the display screen, and the initial target temperature, the final target temperature and the heat preservation time can be preset through the display screen.
[0053] Moreover, in the present invention, the display screen is electrically connected to the rotary motor 41, the microwave generator 71, the heater 91, the blower 92 and the temperature detector 23, and the working parameters of the rotary motor 41, the microwave generator 71, the heater 91, the blower 92 and the temperature detector 23 can be set and displayed through the display screen.
[0054] S2. The synchronization control module 11 controls the microwave heating mechanism 7 and the electric heating mechanism 9 to heat the thawing cavity 2 synchronously according to the temperature value in the thawing cavity 2 collected by the temperature detector 23, so that the temperature in the thawing cavity 2 reaches the initial target temperature; by using the microwave heating mechanism 7 and the electric heating mechanism 9 in combination, the microwave radiation directly acts on the plasma, enabling the plasma to be heated simultaneously inside and outside, so that the temperature in the thawing cavity 2 can quickly rise to the initial target temperature.
[0055] S3. The initial determination module 12 controls the microwave heating mechanism 7 to turn off and the electric heating mechanism 9 to continue heating the thawing cavity 2 according to the temperature value in the thawing cavity 2 collected by the temperature detector 23 after the temperature in the thawing cavity 2 reaches the initial target temperature; after reaching the initial target temperature, the electric heating mechanism 9 can continue to heat the thawing cavity 2 to reach the final target temperature, which can avoid plasma denaturation or degradation caused by excessive microwave heating.
[0056] S4. The final determination module 13 determines the heating rate of the electric heating mechanism 9 according to the temperature value in the thawing cavity 2 collected by the temperature detector 23, the absolute error value between the current temperature in the thawing cavity 2 and the final target temperature, and the absolute error value between the current time and the preset heating-up time.
[0057] S5. The independent control module 14 controls the output duty ratio of the electric heating mechanism 9 according to the heating rate, and controls the electric heating mechanism 9 to heat the thawing cavity 2 at the heating rate, so that the temperature in the thawing cavity 2 reaches the final target temperature; this duty ratio is used to control the voltage across the heater 91, so that the heater 91 works at the corresponding power according to the change of the voltage across it to heat the thawing cavity 2.
[0058] S6. Within the range of the heat preservation time, when the absolute value of the error between the temperature value in the thawing cavity 2 and the final target temperature is greater than or equal to the preset switching threshold, the heat preservation module 15 controls the electric heating mechanism 9 to maintain the final target temperature in the thawing cavity 2 according to the heat preservation time.
[0059] In the present invention, in order to achieve a better heat preservation effect, the preset switching threshold is usually set to 1°C, but it can also be set to other temperature values according to needs, and no limitation is made thereto.
[0060] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be obvious to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but will be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims
1. A slurry melting device, comprising a housing (1), characterized in that: A molten plasma chamber (2) is arranged inside the box body (1), and a temperature measuring device (23) is arranged on the top of the molten plasma chamber (2); a molten plasma rack (6) is arranged inside the molten plasma chamber (2), and a plurality of molten plasma meshes (61) for accommodating blood plasma bags are arranged on the molten plasma rack (6); a microwave heating mechanism (7) is arranged at the rear end of the molten plasma chamber (2), and the output end of the microwave heating mechanism (7) is fixedly connected to a microwave conductor (8) arranged on the inner side of the rear end of the molten plasma chamber (2); electric heating mechanisms (9) are arranged on both sides of the molten plasma chamber (2), and a flow guide (10) is detachably arranged at the output end of the electric heating mechanism (9), and the flow guide (10) is arranged corresponding to the molten plasma mesh (61).
2. The melting slurry device according to claim 1, characterized in that: A turntable (24) is rotatably arranged at the bottom of the molten slurry chamber (2) via a rotating mechanism (4); the turntable (24) is connected to the rotating mechanism (4) via a magnetic coupling mechanism (3); and the molten slurry rack (6) is detachably arranged on the turntable via a limiting mechanism (5).
3. The melting slurry device according to claim 2, characterized in that: The magnetic coupling mechanism (3) comprises a driven magnet (31) arranged at the bottom of the turntable (24) and an active magnet (32) arranged at the output end of the rotating mechanism (4), wherein the active magnet (32) and the driven magnet (31) are arranged corresponding to each other; A driven groove (311) for accommodating a driven magnet (31) is arranged inside the molten slurry chamber (2); a driven limit block (312) is arranged extending outwardly from the axis of the driven groove (311); a driven cover body (313) is arranged outside the driven magnet (31); and a driven limit groove (314) corresponding to the driven limit block (312) is arranged at the axis of the driven cover body (313); An active groove (321) for accommodating an active magnet (32) is arranged outside the molten slurry chamber (2), and an active limit block (322) is arranged extending outward from the axis of the active groove (321); an active cover body (323) is arranged outside the active magnet (32); and an active limit groove (324) corresponding to the active limit block (322) is arranged at the axis of the active cover body (323).
4. The melting slurry device according to claim 3, characterized in that: The rotating mechanism (4) comprises a rotating motor (41) arranged outside the molten pulp chamber (2), and the output end of the rotating motor (41) is transmission-connected to the active magnet (32) of the magnetic coupling mechanism (3) via a coupling (42).
5. The melting slurry device according to claim 4, characterized in that: The limiting mechanism (5) comprises a limiting opening (51) arranged at the top of the rotating disk (24), the inner wall of the limiting opening (51) being covered with a friction block, and a limiting column (52) being provided at the bottom of the melting slurry rack (6), the limiting column (52) being inserted into the limiting opening (51).
6. The melting slurry device according to claim 5, characterized in that: The melting pulp rack (6) is provided with a plurality of slots (62), and a connecting frame (63) is provided on the outer side of the melting pulp mesh (61). Connecting columns (64) are provided on both sides of the connecting frame (63), and the connecting columns (64) can be engaged and connected with the slots (62). A tray is also provided below the melting pulp mesh (61), and the tray is engaged and connected with the slots (62) via the connecting columns (64) provided on both sides.
7. The melting slurry device according to claim 6, characterized in that: The microwave heating mechanism (7) comprises a microwave generator (71) arranged at the rear side of the molten slurry chamber (2); a waveguide tube (72) is provided at the output end of the microwave generator (71); a waveguide hole (73) is provided at the output end of the waveguide tube (72); the waveguide hole (73) is located at the center of the rear end of the molten slurry chamber (2); and a ceramic fixing seat (74) for fixing one end of the microwave conductor (8) is provided at the waveguide hole (73).
8. The melting slurry device according to claim 7, characterized in that: The microwave conductor (8) comprises a microwave guide needle (81) fixedly arranged inside a ceramic fixing seat (74), and a microwave guide strip (82) is fixedly arranged on the top of the microwave guide needle (81); the microwave guide strip (82) is a vortex structure, and the microwave guide strip (82) extends outward from the rear end center position of the molten slurry cavity (2) in a vortex shape.
9. The melting slurry device according to claim 8, characterized in that: The electric heating mechanism (9) comprises a heater (91) arranged outside the two ends of the molten slurry chamber (2), and a blower (92) is arranged at the output end of the heater (91), and the output end of the blower (92) corresponds to the air holes on both sides of the molten slurry chamber (2), and a flow guide (10) is arranged at the air hole in a pluggable manner.
10. A slurry melting method, characterized in that: Using the slurry melting device as claimed in claim 9, the method comprises the following steps: S1. According to the specifications and models of the plasma bag, preset the heating time, determine the initial target temperature, final target temperature and insulation time; S2. The synchronous control module (11) controls the microwave heating mechanism (7) and the electric heating mechanism (9) to synchronously heat the slurry chamber (2) according to the temperature value in the slurry chamber (2) acquired by the temperature detector (23), so that the temperature in the slurry chamber (2) reaches the initial target temperature; S3. The initial determination module (12) controls the microwave heating mechanism (7) to turn off and controls the electric heating mechanism (9) to continue heating the slurry chamber (2) based on the temperature value in the slurry chamber (2) collected by the temperature detector (23) after the temperature in the slurry chamber (2) reaches the initial target temperature; S4. The final determination module (13) determines the heating rate of the electric heating mechanism (9) according to the temperature value in the slurry chamber (2) collected by the temperature detector (23), the absolute error value between the temperature in the slurry chamber (2) at the current moment and the final target temperature, and the absolute error value between the current moment and the preset heating time; S5. The independent control module (14) controls the output duty cycle of the electric heating mechanism (9) according to the heating rate, and controls the electric heating mechanism (9) to heat the molten slurry chamber (2) at the heating rate, so that the temperature in the molten slurry chamber (2) reaches the final target temperature; S6. Within the range of the insulation time, when the absolute value of the error between the temperature value in the slurry chamber (2) and the final target temperature is greater than or equal to a preset switching threshold, the insulation module (15) controls the electric heating mechanism (9) according to the insulation time so that the final target temperature is maintained in the slurry chamber (2).