Folding bag for anaesthesia machine and injection molding process of folding bag

Abstract

The invention discloses a folding bag for an anaesthesia machine and an injection molding process of the folding bag, and relates to the technical field of folding bags. The folding bag for the anesthesia machine is prepared from the following raw materials in parts by weight: 50 parts of natural latex, 50 parts of neoprene latex, 1-3 parts of a stabilizer, 1-2 parts of a sodium p-styrenesulfonate aqueous solution, 3-5 parts of nano silicon dioxide suspension dispersion liquid, 2-3 parts of an anti-aging agent, 5-8 parts of a toughening agent, 5-10 parts of sulfur, 4-8 parts of zinc oxide, 5-10 parts of an accelerant and 3-6 parts of peregal O-20. The folding bag prepared by the invention has good tensile strength, aging resistance and tear resistance.

Description

Technical Field

[0001] The present invention relates to the technical field of folding bladders, and particularly relates to a folding bladder for an anesthesia machine and its injection molding process. Background Art

[0002] An anesthesia machine is an indispensable device in modern medical surgeries, used to provide a stable mixture of anesthetic gas and oxygen for patients during surgeries. As one of the core components of the anesthesia machine, the folding bladder is mainly used to achieve the functions of gas storage, transportation, and manual ventilation. The folding bladder (also known as a corrugated bladder) needs to expand and contract repeatedly during the operation of the anesthesia machine, so it has extremely high requirements for the flexibility, durability, and sealing performance of its materials.

[0003] Currently, folding bladders for anesthesia machines are mainly made of rubber or silicone materials through vulcanization processes. Although these materials have good elasticity and sealing performance, there are still some problems in practical applications; traditional rubber or silicone folding bladders are prone to aging, cracking, etc. after long-term use, especially in the case of high-frequency stretching and contact with anesthetic gases, the chemical stability and fatigue resistance of the materials are insufficient, resulting in a shortened service life. Most existing folding bladders use a simple corrugated pipe structure, and the stress distribution is uneven during repeated stretching and contraction, which is prone to fatigue fracture at the bending points.

[0004] The Chinese patent application with the publication number CN118165385A discloses a polyisoprene rubber air storage bladder, and the prepared air storage bladder has good mechanical properties and antistatic properties, but poor tear resistance. Summary of the Invention

[0005] Aiming at the deficiencies of the existing technology, the purpose of the present invention is to provide a folding bladder for an anesthesia machine and its injection molding process.

[0006] To achieve the above purpose, the present invention is realized through the following technical solutions: A folding bladder for an anesthesia machine, comprising the following raw materials in parts by weight: Natural latex: 50 parts, chloroprene latex: 50 parts, stabilizer: 1 - 3 parts, sodium p-styrenesulfonate aqueous solution: 1 - 2 parts, nano-silica suspension dispersion: 3 - 5 parts, antioxidant: 2 - 3 parts, toughening agent: 5 - 8 parts, sulfur: 5 - 10 parts, zinc oxide: 4 - 8 parts, accelerator: 5 - 10 parts, Peregal O - 20: 3 - 6 parts; The antioxidant is prepared by the following method: S1: Pentaerythritol reacts with 3,6 - dimethyl - 1,4 - dioxane - 2,5 - dione under the catalysis of stannous octoate to form a four - armed star compound; S2: The tetra-arm star compound reacts with 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid under the action of p-toluenesulfonic acid to produce an antioxidant.

[0007] In the step S1, the feeding mass ratio of pentaerythritol to 3,6-dimethyl-1,4-dioxane-2,5-dione is 1:(18 - 20).

[0008] In the step S2, the feeding molar ratio of the tetra-arm star compound to 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid is 1:(2 - 3).

[0009] The toughening agent is prepared by the following method: A1: Oleic acid reacts with formic acid and H2O2 to produce an epoxy compound; A2: The epoxy compound reacts under the action of chromium acetylacetonate to produce a polyester compound; A3: The polyester compound reacts with isophorone diisocyanate under the action of dibutyltin dilaurate to produce a terminal isocyanate group polymer; A4: The terminal isocyanate group polymer reacts with terminal amino silicone oil to produce a toughening agent.

[0010] In the step A1, the feeding mass ratio of oleic acid to formic acid is 16:5; in the step A2, the feeding mass ratio of the epoxy compound to chromium acetylacetonate is 50:1; in the step A3, the feeding mass ratio of the polyester compound to isophorone diisocyanate is 10:1; in the step A4, the feeding mass ratio of the terminal isocyanate group polymer to terminal amino silicone oil is 6:1.

[0011] The stabilizer is a 10 - 25wt% aqueous potassium hydroxide solution.

[0012] The accelerator is one of accelerator TMTD and accelerator BZ.

[0013] The mass concentration of the aqueous sodium p-styrenesulfonate solution is 25 - 30wt%.

[0014] The antioxidant, toughening agent, sulfur, zinc oxide, accelerator, and Peregal O-20 are all aqueous dispersions with a total solid content of 50wt%; the aqueous dispersions are all ground by a nano-abrasive machine until the D90 of the dispersion is not more than 3 microns, and 0.6wt% of sodium methylene bisnaphthalenesulfonate is added as a surfactant to the ground aqueous dispersion.

[0015] An injection molding process for a folding bladder used in an anesthesia machine includes the following steps: (1) Weigh by parts by weight: natural rubber latex: 50 parts, chloroprene rubber latex: 50 parts, stabilizer: 1 - 3 parts, sodium p-styrenesulfonate aqueous solution: 1 - 2 parts, nano-silica suspension: 3 - 5 parts, anti-aging agent: 2 - 3 parts, toughening agent: 5 - 8 parts, sulfur: 5 - 10 parts, zinc oxide: 4 - 8 parts, accelerator: 5 - 10 parts, Peregal O-20: 3 - 6 parts; (2) Stir and mix the above raw materials evenly, keep stirring at 45°C, pre-vulcanize for 1.5 h, then stand still at room temperature for 48 h to obtain the cured latex; (3) Clean the mold, dry it at 80°C for 5 minutes; immerse it in a 20 wt% calcium nitrate aqueous solution, and dry the coagulant at 90°C for 5 minutes; (4) Immerse the cured latex, dry the latex at 80°C for 5 minutes; leach at 60 ± 5°C and perform edge curling treatment; perform dry vulcanization treatment on the curled latex, dry and vulcanize at 110°C for 25 min; demold, wash with 60°C hot water, leach and perform post-treatment to obtain a folding bladder for an anesthesia machine.

[0016] Due to the above technical solutions, the beneficial effects of the present invention include: (1) The anti-aging agent prepared by the present invention combines a four-arm star-shaped core with multiple antioxidant functional groups, realizing the synergistic optimization of anti-aging performance and mechanical properties. It not only enhances the free radical capture efficiency and thermal stability, but also improves the tensile properties through molecular chain flexibility and crosslinking network, and is particularly suitable for the folding bladder material under high dynamic stress environment.

[0017] (2) The toughening agent prepared by the present invention endows the folding bladder with excellent anti-fatigue property and toughness through the synergistic effect of polyester and flexible silicone, meeting the core requirements of repeated deformation, environmental tolerance and long-term stability in the application of the folding bladder. Specific Embodiments

[0018] The following is further illustrated with reference to embodiments, but the present invention is not limited to these embodiments.

[0019] Example 1 Preparation of anti-aging agent: S1: Under nitrogen protection, add 1000 g of DMF, 10 g of pentaerythritol and 180 g of 3,6-dimethyl-1,4-dioxane-2,5-dione to the reactor, stir and mix evenly, heat up to 130°C, stir for 15 min, then add 10 g of catalyst stannous octoate, after reacting for 20 h, cool to room temperature, perform vacuum distillation at 60°C for 2 h to obtain the crude product. Add the crude product to 500 ml of chloroform and stir evenly, then add 500 ml of cold methanol, let it stand to precipitate, and then wash it three times with methanol (300 ml each time), and dry it in vacuum at 60°C for 5 h to obtain a four-arm star-shaped compound with a number average molecular weight of 1864; The reaction equation is shown as follows: .

[0020] S2: Under nitrogen protection, add 1200 g of toluene, 0.1 mol of tetra-armed star compound, and 0.2 mol of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid into the reactor, stir and mix evenly, heat up to 80 °C, then add 15 g of p-toluenesulfonic acid, react for 6 h (remove the generated water using a water separator during the reaction), then cool to room temperature, slowly add saturated sodium bicarbonate solution to adjust the pH to neutral, stir well for 30 min, let it stand for liquid separation, transfer the organic phase to a rotary evaporator, distill under reduced pressure at 60 °C for 4 h, and dry under vacuum at 70 °C for 10 h to obtain the antioxidant; the number average molecular weight is 3096, and the reaction equation is shown as follows: .

[0021] During this reaction process, partial hydroxyl groups of the tetra-armed star compound react with the carboxylic acid of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid to undergo an esterification reaction.

[0022] Example 2 Preparation of antioxidant: S1: Under nitrogen protection, add 1000 g of DMF, 10 g of pentaerythritol and 190 g of 3,6-dimethyl-1,4-dioxane-2,5-dione into the reactor, stir and mix evenly, heat up to 130 °C, stir for 15 min, then add 10 g of catalyst stannous octoate, react for 24 h, then cool to room temperature, distill under reduced pressure at 60 °C for 2 h to obtain the crude product, add the crude product into 500 ml of chloroform, stir and mix evenly, then add 500 ml of cold methanol, let it stand to precipitate, then wash with methanol three times (300 ml each time), and dry under vacuum at 60 °C for 5 h to obtain the tetra-armed star compound, and the number average molecular weight is 2152; S2: Under nitrogen protection, add 1200 g of toluene, 0.1 mol of tetra-armed star compound, and 0.25 mol of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid into the reactor, stir and mix evenly, heat up to 90 °C, then add 15 g of p-toluenesulfonic acid, react for 5 h (remove the generated water using a water separator during the reaction), then cool to room temperature, slowly add saturated sodium bicarbonate solution to adjust the pH to neutral, stir well for 30 min, let it stand for liquid separation, transfer the organic phase to a rotary evaporator, distill under reduced pressure at 60 °C for 4 h, and dry under vacuum at 70 °C for 10 h to obtain the antioxidant, and the number average molecular weight is 3692.

[0023] Example 3 Preparation of Antioxidant: S1: Under nitrogen protection, add 1000 g of DMF, 10 g of pentaerythritol and 200 g of 3,6-dimethyl-1,4-dioxane-2,5-dione into the reactor, stir and mix evenly, heat up to 130 °C, stir for 15 min, then add 10 g of stannous octoate catalyst, after reacting for 26 h, cool to room temperature, carry out reduced pressure distillation at 60 °C for 2 h to obtain the crude product. Add the crude product into 500 ml of chloroform, stir and mix evenly, then add 500 ml of cold methanol, let it stand to precipitate, and then wash it three times with methanol (300 ml each time), and dry it in vacuum at 60 °C for 5 h to obtain a four-armed star compound; the number average molecular weight is 2440; S2: Under nitrogen protection, add 1200 g of toluene, 0.1 mol of four-armed star compound, and 0.3 mol of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid into the reactor, stir and mix evenly, heat up to 100 °C, then add 15 g of p-toluenesulfonic acid, after reacting for 4 h (removing the generated water using a water separator during the reaction), cool to room temperature, slowly add saturated sodium bicarbonate solution to adjust the pH to neutral, stir well for 30 min, let it stand for liquid separation, transfer the organic phase to a rotary evaporator, carry out reduced pressure distillation at 60 °C for 4 h, and dry it in vacuum at 70 °C for 10 h to obtain the antioxidant, and the number average molecular weight is 4288.

[0024] Example 4 Preparation of Toughness Agent: A1: Add 800 ml of DMF, 160 g of oleic acid, and 10 g of strong acid cation exchange resin into the reactor, stir and mix evenly, heat up to 50 °C, then mix 50 g of formic acid and 160 g of 30 wt% H2O2 solution evenly, slowly add the mixed solution of formic acid and H2O2 solution, dropwise add for 20 min, after reacting for 8 h, cool to room temperature, transfer the upper clear liquid to a separatory funnel, let it stand and drain the lower inorganic liquid, and extract three times with petroleum ether (200 ml each time), carry out reduced pressure distillation at 50 °C for 5 h to obtain an epoxy compound; the reaction equation is shown as follows: 。

[0025] A2: Add 500 g of epoxy compound and 10 g of chromium acetylacetonate into the reactor, stir, heat up to 170 °C and react for 5 h, then cool to room temperature, add 800 ml of methanol, stir, precipitate, filter, and dry it in vacuum at 50 °C for 3 h to obtain a polyester compound; the reaction equation is shown as follows: 。

[0026] A3: Under nitrogen protection, add 500 g of DMF and 100 g of polyester compound into the reactor, stir and mix evenly, heat up to 70 °C, then slowly dropwise add 10 g of isophorone diisocyanate over 20 min. After dropping, add 5 g of catalyst dibutyltin dilaurate, react for 6 h, then add 500 ml of ice water for precipitation and filtration, and dry in vacuum at 40 °C for 12 h to obtain an isocyanate-terminated polymer; the reaction equation is shown as follows: 。

[0027] A4: Under nitrogen protection, add 500 g of DMF and 60 g of isocyanate-terminated polymer into the reactor, stir and mix evenly, heat up to 70 °C, then add 10 g of amino-terminated silicone oil and 5 g of catalyst dibutyltin dilaurate, react for 6 h, then add 500 ml of ice water for precipitation and filtration, and dry in vacuum at 40 °C for 12 h to obtain a toughening agent; in this reaction, the isocyanate groups in the isocyanate-terminated polymer react with the amino groups in the amino-terminated silicone oil.

[0028] Example 5 Preparation of a folding bladder for an anesthesia machine: (1)Weigh: natural rubber latex: 500 g, chloroprene rubber latex: 500 g, stabilizer (10 wt% aqueous potassium hydroxide solution): 10 g, sodium p-styrenesulfonate aqueous solution (25 wt%): 10 g, nano-silica suspension: 30 g, anti-aging agent (prepared in Example 1): 20 g, toughening agent (prepared in Example 4): 50 g, sulfur: 50 g, zinc oxide: 40 g, accelerator (accelerator TMTD): 50 g, Peregal O-20: 30 g; (2)Stir and mix the above raw materials evenly, keep stirring at 45 °C for pre-vulcanization for 1.5 h, then stand still at room temperature for 48 h to obtain a matured latex; (3)Clean the mold, dry it at 80 °C for 5 minutes; dip it in a 20 wt% aqueous calcium nitrate solution, and dry the coagulant at 90 °C for 5 minutes; (4)Dip the matured latex, dry the latex at 80 °C for 5 minutes; leach at 60 ± 5 °C and perform a curling treatment; perform a drying and vulcanization treatment on the curled latex, dry and vulcanize at 110 °C for 25 min; demold, wash with hot water at 60 °C, leach and dry at 40 °C to obtain a folding bladder for an anesthesia machine.

[0029] Example 6 Preparation of a folding bladder for an anesthesia machine: (1) Weigh: natural rubber latex: 500 g, chloroprene rubber latex: 500 g, stabilizer (15 wt% potassium hydroxide aqueous solution): 20 g, sodium p-styrenesulfonate aqueous solution (28 wt%): 15 g, nano-silica suspension: 40 g, anti-aging agent (prepared in Example 2): 25 g, toughening agent (prepared in Example 4): 60 g, sulfur: 80 g, zinc oxide: 60 g, accelerator (accelerator TMTD): 80 g, Peregal O-20: 50 g; (2) Stir and mix the above raw materials evenly, keep stirring at 45 °C, pre-vulcanize for 1.5 h, and then stand still at room temperature for 48 h to obtain a cured latex; (3) Clean the mold, dry it at 80 °C for 5 minutes; immerse it in a 20 wt% calcium nitrate aqueous solution, and dry the coagulant at 90 °C for 5 minutes; (4) Immerse the cured latex, dry the latex at 80 °C for 5 minutes; leach at 60 ± 5 °C and perform edge curling treatment; perform dry vulcanization treatment on the edge-curled latex, dry and vulcanize at 110 °C for 25 min; demold, wash with 60 °C hot water, leach and dry at 40 °C to obtain a folding bladder for an anesthesia machine.

[0030] Example 7 Preparation of a folding bladder for an anesthesia machine: (1) Weigh: natural rubber latex: 500 g, chloroprene rubber latex: 500 g, stabilizer (25 wt% potassium hydroxide aqueous solution): 30 g, sodium p-styrenesulfonate aqueous solution (30 wt%): 20 g, nano-silica suspension: 50 g, anti-aging agent (prepared in Example 3): 30 g, toughening agent (prepared in Example 4): 80 g, sulfur: 100 g, zinc oxide: 80 g, accelerator (accelerator BZ): 100 g, Peregal O-20: 60 g; (2) Stir and mix the above raw materials evenly, keep stirring at 45 °C, pre-vulcanize for 1.5 h, and then stand still at room temperature for 48 h to obtain a cured latex; (3) Clean the mold, dry it at 80 °C for 5 minutes; immerse it in a 20 wt% calcium nitrate aqueous solution, and dry the coagulant at 90 °C for 5 minutes; (4) Immerse the cured latex, dry the latex at 80 °C for 5 minutes; leach at 60 ± 5 °C and perform edge curling treatment; perform dry vulcanization treatment on the edge-curled latex, dry and vulcanize at 110 °C for 25 min; demold, wash with 60 °C hot water, leach and dry at 40 °C to obtain a folding bladder for an anesthesia machine.

[0031] Comparative Example 1 The raw material components and ratios of the folding bladder are basically the same as those in Example 6, except that the anti-aging agent is replaced with an equal mass of an anti-aging agent prepared by the following method: The preparation method of the antioxidant is basically the same as that of Example 2, except that the pentaerythritol in step S1 is replaced with 1,4-butanediol of the same weight.

[0032] Comparative Example 2 The raw material components and their ratios of the folding capsule are basically the same as those of Example 6, except that the antioxidant is replaced with an antioxidant of the same mass prepared by the following method: The preparation method of the antioxidant is basically the same as that of Example 2, except that the addition amount of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid in step S2 is 0.4 mol.

[0033] Comparative Example 3 The raw material components and their ratios of the folding capsule are basically the same as those of Example 6, except that the antioxidant is replaced with an antioxidant of the same mass prepared by the following method: The preparation method of the antioxidant is basically the same as that of Example 2, except that 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutyric acid in step S2 is replaced with 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid of the same molar amount.

[0034] Comparative Example 4 The raw material components and their ratios of the folding capsule are basically the same as those of Example 6, except that the toughening agent is replaced with a toughening agent of the same mass prepared by the following method: The preparation method of the toughening agent is basically the same as that of Example 4, except that the polyester compound in step A3 is replaced with castor oil of the same weight.

[0035] Comparative Example 5 The raw material components and their ratios of the folding capsule are basically the same as those of Example 6, except that the toughening agent is replaced with the terminal isocyanate group polymer prepared in step A3 of Example 4 of the same mass.

[0036] Comparative Example 6 The raw material components and their ratios of the folding capsule are basically the same as those of Example 6, except that the toughening agent is replaced with a toughening agent of the same mass prepared by the following method: The preparation method of the toughening agent is basically the same as that of Example 4, except that the terminal amino silicone oil in step A4 is replaced with hexamethylenediamine of the same weight.

[0037] It should be noted that the anti-aging agents, toughening agents, sulfur, zinc oxide, accelerators, and Peregal O-20 used in Examples 5-7 and Comparative Examples of this application are all aqueous dispersions with a total solid content of 50 wt%; the preparation method of the aqueous dispersion is as follows: after mixing the above anti-aging agents, toughening agents, sulfur, zinc oxide, accelerators, and Peregal O-20 with equal weights of water respectively, then adding sodium methylene dinaphthalene sulfonate accounting for 0.6 wt% of the total weight of the aqueous dispersion as a surfactant, and grinding with a nano-abrasive machine until the D90 of the dispersion is not greater than 3 microns to obtain an aqueous dispersion with a total solid content of 50 wt%.

[0038] The nano-silica suspension dispersion used in the examples and comparative examples of this application is the SS-S10WJ type produced by Hangzhou Jikang New Materials Co., Ltd., with a silica particle size of 8-15 nm and a concentration of 30 wt% aqueous dispersion; the natural rubber latex is the IR-550 natural rubber latex produced by Puyang Lin's Chemical New Materials Co., Ltd., with a solid content of 50 wt%; the chloroprene rubber latex is SKYPRENE LATEX LA-502, with a solid content of 50 wt%; the sulfur is the S-80 type special sulfur powder produced by Qingdao Luchuan Chemical Co., Ltd., mesh number: 400 mesh; the end-amino silicone oil model is Cheersil 8110, produced by Suzhou Qitian New Materials Co., Ltd.

[0039] Unless otherwise specified, the weighed weights shown in Examples 5-7 and Comparative Examples of this application are all the weights of the aqueous dispersions. Example illustration: In Example 6, the 500 g of natural rubber latex weighed is 500 g of natural rubber latex with a solid content of 50 wt%, and the effective weight of the natural rubber latex is 250 g; the 25 g of anti-aging agent weighed is the 50 wt% anti-aging agent aqueous dispersion, and its effective anti-aging agent weight is 12.5 g.

[0040] The folding capsules of Examples 5-7 and Comparative Examples 1-6 of this application were subjected to tensile strength and elongation at break performance tests according to ASTM D412-16(2021), and the tear strength was carried out according to the trouser tear method of GB / T 529-2008. The test results are shown in Table 1.

[0041] Aging test: The folding capsules of Examples 5-7 and Comparative Examples 1-6 of this application were placed in a hot air aging oven and aged at 100 °C for 5 days, and then relevant performance tests were carried out. The test results are shown in Table 1.

[0042] Table 1 Performance data table

[0043] It can be seen from Examples 5, 6, and 7 in Table 1 that the folding capsule of the present invention has excellent mechanical properties, anti-aging properties, and tear resistance.

[0044] The antioxidant prepared by the present invention has a four-armed star topology. The four-armed structure with pentaerythritol as the core endows the antioxidant with a higher molecular weight and three-dimensional steric hindrance. At the same time, the four-armed star topology is tightly combined with the matrix material through physical entanglement and polar interactions, greatly reducing its migration rate in the polymer matrix and improving the migration resistance. In addition, the multi-armed design of the star structure makes the antioxidant groups more evenly distributed and the local concentration moderate, avoiding agglomeration. The thioether group can decompose peroxides, form a synergistic effect with phenolic hydroxyl groups, inhibit thermal-oxidative degradation, delay the yellowing and embrittlement of materials, and significantly improve the antioxidant efficiency. The thioether group plays a stress relaxation role to a certain extent and reduces stress concentration. The introduction of polyester segments can improve the flexibility of the material, avoid local fracture, and thus enhance the tensile strength and elongation at break.

[0045] The urethane bond and urea bond in the toughening agent prepared by the present invention can form a strong hydrogen bond network. These hydrogen bonds are reversibly broken and recombined under external force, avoiding direct tearing caused by stress concentration, and can significantly improve the elongation at break of the material. The introduced silicon-oxygen main chain in the toughening agent has an extremely low rotational hindrance. The low glass transition temperature of the silicone chain endows the material with low-temperature toughness, making the folding capsule not easy to crack during repeated folding. At the same time, the molecular chain slip ability of the silicone chain can absorb mechanical energy and improve the fatigue resistance.

[0046] In Comparative Example 1, after replacing pentaerythritol with 1,4-butanediol, since it only contains two hydroxyl groups (far lower than the four hydroxyl groups of pentaerythritol), the synthesized antioxidant cannot form a four-armed star crosslinked structure, its dispersion performance and free radical capture efficiency decrease, and the anti-aging performance decreases.

[0047] In Comparative Example 2, too many hindered phenol anti-aging groups are grafted, the molecular volume increases, and its dispersion performance in the compounded system decreases, which in turn leads to uneven distribution of hindered phenols and causes deterioration of the anti-aging performance.

[0048] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. However, for those of ordinary skill in the art, without departing from the scope of the technical solution of the present invention, some equivalent changes such as slight modifications, evolutions made by using the technical content disclosed above are all equivalent embodiments of the present invention. At the same time, any equivalent changes, modifications, and evolutions made to the above embodiments based on the essential technology of the present invention still fall within the protection scope of the technical solution of the present invention.

Claims

1. A folding bladder for an anesthesia machine, characterized in that, Comprising raw materials in the following parts by weight: Natural latex: 50 parts, chloroprene latex: 50 parts, stabilizer: 1 - 3 parts, sodium p-styrenesulfonate aqueous solution: 1 - 2 parts, nano-silica suspension dispersion: 3 - 5 parts, antioxidant: 2 - 3 parts, toughening agent: 5 - 8 parts, sulfur: 5 - 10 parts, zinc oxide: 4 - 8 parts, accelerator: 5 - 10 parts, Peregal O - 20: 3 - 6 parts; The antioxidant is prepared by the following method: S1: Pentaerythritol reacts with 3,6 - dimethyl - 1,4 - dioxane - 2,5 - dione under the catalysis of stannous octoate to form a four - armed star - shaped compound; S2: The four - armed star - shaped compound reacts with 4-(2,6 - di - tert - butyl - 4-(2-(3,5 - di - tert - butyl - 4 - hydroxyphenylthio)propan - 2 - ylthio)phenoxy)-4 - oxobutyric acid under the action of p - toluenesulfonic acid to form the antioxidant.

2. The folding bladder for an anesthesia machine according to claim 1, wherein In the step S1, the feeding mass ratio of pentaerythritol to 3,6 - dimethyl - 1,4 - dioxane - 2,5 - dione is 1:(18 - 20).

3. A folding bladder for an anesthesia machine according to claim 1, wherein, In the step S2, the feeding molar ratio of the four - armed star - shaped compound to 4-(2,6 - di - tert - butyl - 4-(2-(3,5 - di - tert - butyl - 4 - hydroxyphenylthio)propan - 2 - ylthio)phenoxy)-4 - oxobutyric acid is 1:(2 - 3).

4. A folding bladder for an anesthesia machine according to claim 1, wherein, The toughening agent is prepared by the following method: A1: Oleic acid reacts under the action of formic acid and H2O2 to form an epoxide; A2: The epoxide reacts under the action of chromium acetylacetonate to form a polyester compound; A3: The polyester compound reacts with isophorone diisocyanate under the action of dibutyltin dilaurate to form a terminal isocyanate - group polymer; A4: The terminal isocyanate - group polymer reacts with amino - terminated silicone oil to form the toughening agent.

5. The folding bladder for an anesthesia machine according to claim 4, wherein, In the step A1, the feeding mass ratio of oleic acid to formic acid is 16:5; in the step A2, the feeding mass ratio of the epoxide to chromium acetylacetonate is 50:1; in the step A3, the feeding mass ratio of the polyester compound to isophorone diisocyanate is 10:1; in the step A4, the feeding mass ratio of the terminal isocyanate - group polymer to amino - terminated silicone oil is 6:

1.

6. The folding bladder for an anesthesia machine according to claim 1, characterized in that, The stabilizer is a 10 - 25wt% potassium hydroxide aqueous solution.

7. The folding bladder for an anesthesia machine according to claim 1, wherein, The accelerator is one of accelerator TMTD and accelerator BZ.

8. The folding bladder for an anesthesia machine according to claim 1, characterized in that, The mass concentration of the sodium p - styrenesulfonate aqueous solution is 25 - 30wt%.

9. The folding bladder for anesthetic machine according to claim 1, wherein The antioxidant, toughening agent, sulfur, zinc oxide, accelerator, and Peregal O - 20 all adopt aqueous dispersions with a total solid content of 50wt%; the aqueous dispersions are all ground by a nano - abrasive machine until the D90 of the dispersion is not more than 3 microns, and 0.6wt% of sodium methylene dinaphthalene sulfonate is added as a surfactant to the ground aqueous dispersion.

10. The injection molding process of the folding bladder for an anesthesia machine according to any one of claims 1-9, characterized in that, Comprising the following steps: (1)Weigh by parts by weight: natural latex: 50 parts, chloroprene latex: 50 parts, stabilizer: 1 - 3 parts, sodium p-styrenesulfonate aqueous solution: 1 - 2 parts, nano-silica suspension dispersion: 3 - 5 parts, anti-aging agent: 2 - 3 parts, toughening agent: 5 - 8 parts, sulfur: 5 - 10 parts, zinc oxide: 4 - 8 parts, accelerator: 5 - 10 parts, Peregal O-20: 3 - 6 parts; (2)Stir and mix the above raw materials evenly, keep stirring at 45°C for 1.5 h, then stand still at room temperature for 48 h to obtain the matured latex; (3)Clean the mold, dry it at 80°C for 5 minutes; dip it in a 20wt% calcium nitrate aqueous solution coagulant, and dry the coagulant at 90°C for 5 minutes; (4)Dip the matured latex, dry the latex at 80°C for 5 minutes; leach at 60 ± 5°C and perform edge curling treatment; perform drying and vulcanization treatment on the edge-curled latex, dry and vulcanize at 110°C for 25 min; demold, wash with 60°C hot water, leach and perform post-treatment to obtain a folding bladder for an anesthesia machine.

Images