Bone marrow cell pushing device

Abstract

The invention discloses a bone marrow cell pushing device, and relates to the technical field of cell pushing, the bone marrow cell pushing device comprises a placing plate, the side surface of the placing plate is provided with a bottom plate, the upper part of the bottom plate is movably connected with a first movable box, the upper part of the first movable box is slidably provided with a second movable box, and the end part of the second movable box is rotatably connected with a connecting rod; a pushing piece is detachably installed at the end, away from the second movable box, of the connecting rod, and a pushing assembly used for the pushing piece is arranged on the first movable box. The pushing assembly comprises a third rack slidably arranged on the first movable box, a sliding block slidably arranged on the inner side of the first movable box, a first gear rotationally connected with the inner side of the first movable box, and a first rack installed on the side face of the sliding block. According to the invention, by arranging the pushing assembly, the uniformity of the speed during pushing can be better controlled in a pressing manner, the speed change possibly occurring during direct pushing is avoided, the cells can be ensured to be uniformly distributed on the glass slide, and the condition of cell overlapping or gathering is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of cell smear techniques, and particularly to a bone marrow cell smearer. Background Art

[0002] Bone marrow cells are the general term for various cells in the bone marrow. Bone marrow is the tissue existing in the lacunae of cancellous bone and the medullary cavity of long bones, which is composed of various types of cells and reticular connective tissue. A bone marrow cell smear generally refers to a technical method of evenly smearing bone marrow fluid on a glass slide during a bone marrow examination. Specifically, the operator drops the bone marrow fluid at one end of the glass slide, and then uses a smearer to start from one side of the bone marrow fluid drop and steadily push it to the other side, so that the bone marrow fluid is evenly spread to form a thin film, which is an important step in bone marrow examination.

[0003] However, during the smearing process, it is required that the operator master the correct strength and speed to ensure that the bone marrow fluid is evenly spread under the smearer. At the same time, attention should also be paid to the angle of the smearer and the point of contact with the bone marrow fluid to obtain the best smear effect. If the operation is improper, during the manual smearing process, due to the shaking of the hand, the strength, angle or speed during smearing will change, resulting in insufficient smearing accuracy, and air may enter the smear, interfering with the observation of bone marrow cells. Therefore, a bone marrow cell smearer is proposed. Summary of the Invention

[0004] The purpose of the present invention is to solve the defect that during smearing, the strength, angle or speed may change, which may cause air to enter the smear and interfere with the observation of bone marrow cells in the prior art, and to propose a bone marrow cell smearer.

[0005] In order to achieve the above purpose, the present invention adopts the following technical scheme:

[0006] A bone marrow cell smearer, comprising a placement plate, a bottom plate is installed on the side of the placement plate, a first movable box is movably connected to the upper part of the bottom plate, a second movable box is slidably arranged on the upper part of the first movable box, a connecting rod is rotatably connected to the end of the second movable box, a smearer is detachably installed at one end of the connecting rod away from the second movable box, a pushing component for the smearer is arranged on the first movable box, the pushing component includes a third rack slidably arranged on the first movable box, a sliding block slidably arranged inside the first movable box, a first gear rotatably connected inside the first movable box, and a first rack installed on the side of the sliding block, the sliding block is fixedly connected to the second movable box, the third rack moves downward to drive the first rack to move through the first gear, when the first rack moves, it drives the sliding block to move horizontally, when the sliding block moves, it drives the smearer to move on the glass slide on the placement plate through the second movable box, and the uniformity of the speed during smearing can be better controlled by pressing, avoiding the possible speed change during direct pushing. A moving resistance adjustment component for the smearer is arranged on the sliding block, the moving resistance adjustment component includes movable blocks symmetrically and movably connected to the outside of the sliding block, rotating wheels rotatably connected to the inside of the movable blocks, and a third threaded rod rotatably connected to the inside of the sliding block, when the third threaded rod rotates, it can drive the two movable blocks to move towards each other, when the two movable blocks move towards each other, it can increase or decrease the contact force between the rotating wheel and the first movable box, and by adjusting the resistance when the sliding block moves, the speed of the smearer during smearing can be controlled according to the viscosity of the bone marrow fluid or the cell density size;

[0007] An adjustment component for the smearer is arranged on the second movable box, the adjustment component includes a rotating handle rotatably connected to the second movable box, a second rack slidably arranged inside the second movable box, a second gear rotatably connected inside the second movable box, and a rotating rod installed on the side of the second gear, the rotating rod is fixedly connected to the connecting rod, when the rotating handle rotates, it drives the second rack to move horizontally, when the second rack moves, it drives the second gear to rotate, and the second gear rotates to drive the smearer to perform a circular motion through the rotating rod and the connecting rod, and the required angle can be prepared before the smearing work.

[0008] The above technical solution further includes:

[0009] A square block is installed on the upper part of the bottom plate, the square block is movably connected to the first movable box, a first threaded rod is rotatably connected to the upper part of the bottom plate, and the first threaded rod is threadedly connected to the first movable box, and the contact force adjustment can be prepared before the smearing work.

[0010] A sliding groove is formed in the upper part of the first movable box. A guide rod is installed inside the sliding groove. The sliding block is slidably arranged inside the sliding groove. The sliding block is movably connected to the guide rod, ensuring that the sliding block moves along the sliding groove under the guidance of the guide rod.

[0011] A first gear is rotatably connected inside the sliding groove. A housing is installed on the side of the first movable box. The third rack is slidably arranged inside the housing. The third rack is fixedly connected to the movable plate. Both the third rack and the first rack are meshed with the first gear. When the third rack moves downward, it can drive the first gear to rotate and simultaneously drive the first rack to move horizontally.

[0012] A pushing block is slidably arranged inside the second movable box. The pushing block is in threaded connection with the second threaded rod. One end of the second threaded rod away from the pushing block is fixedly connected to the rotating handle. By rotating the rotating handle on the outside of the second movable box, the pushing block is driven to move horizontally.

[0013] One side of the pushing block away from the second threaded rod is fixedly connected to the second rack. The second rack is meshed with the second gear. When the pushing block drives the second rack to move horizontally, the second gear can be driven to rotate.

[0014] An indicating needle is installed at one end of the rotating rod outside the second movable box. A scale line is installed on one side of the second movable box close to the indicating needle. The position indicated by the indicating needle on the scale line can facilitate observing the position of the pushing piece at this time.

[0015] One side of the movable block close to the extrusion block is provided with a telescopic rod and a spring. The ends of the telescopic rod and the spring away from the movable block are jointly installed with a pressure-receiving block. A third threaded rod is slidably arranged inside the sliding block. The third threaded rod is in threaded connection with the extrusion block. When the third threaded rod rotates to drive the extrusion block to move, the two pressure-receiving blocks can be extruded.

[0016] The cross-section of the pressure-receiving block is trapezoidal, and the pressure-receiving block is on the movement track of the third threaded rod, which is convenient for being extruded by the extrusion block.

[0017] The size of the inner opening of the second movable box is adapted to the size of the pushing block, making the movement of the pushing block more stable.

[0018] The present invention has the following beneficial effects:

[0019] 1. In the present invention, by setting the adjustment assembly and the first threaded rod, the required angle and contact force adjustment can be prepared before the pushing piece works, avoiding uneven force or angle change that may occur during direct pushing, and improving the precision of the pushing piece.

[0020] 2. In the present invention, by setting the pushing component, the uniformity of the speed when pushing the slide can be better controlled by pressing, avoiding the possible speed change during direct pushing, ensuring the uniform distribution of cells on the slide, making cell observation and analysis more accurate, and by adjusting the resistance of the moving resistance adjustment component when the slider moves, thereby controlling the speed when the slide is pushed according to the viscosity of the bone marrow fluid or the cell density. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 FIG. is a schematic diagram of the overall structure of a bone marrow cell spreader proposed by the present invention;

[0022] Figure 2 FIG. is a schematic cross-sectional view of the side of the first movable box in the present invention;

[0023] Figure 3 FIG. is a schematic cross-sectional view of the side of the second movable box in the present invention;

[0024] Figure 4 FIG. is a schematic cross-sectional view of the inside of the slider in the present invention;

[0025] Figure 5 is Figure 1 an enlarged schematic view of the structure at A in;

[0026] Figure 6 is Figure 2 an enlarged schematic view of the structure at B in;

[0027] Figure 7 is Figure 2 an enlarged schematic view of the structure at C in;

[0028] Figure 8 is Figure 3 an enlarged schematic view of the structure at D in;

[0029] Figure 9 is Figure 4 an enlarged schematic view of the structure at E in.

[0030] In the figure: 1. Placing plate; 2. Bottom plate; 3. Square block; 4. First movable box; 5. First threaded rod; 6. Sliding groove; 7. Guide rod; 8. Slider; 9. First rack; 10. First gear; 11. Outer housing; 12. Third rack; 13. Movable plate; 14. Second movable box; 15. Second threaded rod; 16. Rotating handle; 17. Second rack; 18. Second gear; 19. Rotating rod; 20. Connecting rod; 21. Slide; 22. Pointer; 23. Scale line; 24. Movable block; 25. Telescopic rod; 26. Spring; 27. Compressed block; 28. Extrusion block; 29. Threaded rod; 30. Rotating wheel; 31. Pushing block. DETAILED DESCRIPTION OF THE INVENTION

[0031] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0032] Embodiment 1

[0033] As Figures 1 - 9 shown, a bone marrow cell smearer proposed by the present invention includes a placement plate 1. A bottom plate 2 is installed on the side of the placement plate 1. A first movable box 4 is movably connected to the upper part of the bottom plate 2. A second movable box 14 is slidably arranged on the upper part of the first movable box 4. One end of the connecting rod 20 is rotatably connected to the second movable box 14. A smearer 21 is detachably installed at the end of the connecting rod 20 away from the second movable box 14. A pushing assembly for the smearer 21 is arranged on the first movable box 4. The pushing assembly includes a third rack 12 slidably arranged on the first movable box 4, a sliding block 8 slidably arranged inside the first movable box 4, a first gear 10 rotatably connected inside the first movable box 4, and a first rack 9 installed on the side of the sliding block 8. A fixed connection is established between the sliding block 8 and the second movable box 14. When the third rack 12 moves downward, the first gear 10 drives the first rack 9 to move. When the first rack 9 moves, it drives the sliding block 8 to move horizontally. When the sliding block 8 moves, it drives the smearer 21 to move on the glass slide on the placement plate 1 through the second movable box 14. By pressing, the uniformity of the speed during smearing can be better controlled, avoiding the possible speed changes during direct pushing. A moving resistance adjustment assembly for the smearer 21 is arranged on the sliding block 8. The moving resistance adjustment assembly includes movable blocks 24 symmetrically and movably connected to the outside of the sliding block 8, rotating wheels 30 rotatably connected to the inside of the movable blocks 24, and a third threaded rod 29 rotatably connected to the inside of the sliding block 8. When the third threaded rod 29 rotates, it can drive the two movable blocks 24 to move towards each other. When the two movable blocks 24 move towards each other, the contact force between the rotating wheels 30 and the first movable box 4 can be increased or decreased. By adjusting the resistance when the sliding block 8 moves, the speed of the smearer 21 during smearing movement can be controlled according to the viscosity of the bone marrow fluid or the cell density.

[0034] An adjustment component for pushing the film 21 is provided on the second movable box 14. The adjustment component includes a rotating handle 16 rotatably connected to the second movable box 14, a second rack 17 slidably arranged inside the second movable box 14, a second gear 18 rotatably connected inside the second movable box 14, and a rotating rod 19 mounted on the side of the second gear 18. The rotating rod 19 is fixedly connected to the connecting rod 20. When the rotating handle 16 rotates, it drives the second rack 17 to move horizontally. When the second rack 17 moves, it drives the second gear 18 to rotate. The rotation of the second gear 18 drives the film pushing piece 21 to perform a circular motion through the rotating rod 19 and the connecting rod 20, and the required angle can be prepared before the film pushing operation.

[0035] A square block 3 is installed on the upper part of the bottom plate 2. The square block 3 is movably connected to the first movable box 4. A first threaded rod 5 is rotatably connected to the upper part of the bottom plate 2. The first threaded rod 5 is threadedly connected to the first movable box 4, and the contact force adjustment can be prepared before the film pushing operation.

[0036] A pushing block 31 is slidably arranged inside the second movable box 14. The pushing block 31 is threadedly connected to the second threaded rod 15. One end of the second threaded rod 15 away from the pushing block 31 is fixedly connected to the rotating handle 16. By rotating the rotating handle 16 on the outside of the second movable box 14, the pushing block 31 is driven to move horizontally.

[0037] One side of the pushing block 31 away from the second threaded rod 15 is fixedly connected to the second rack 17. The second rack 17 is meshed with the second gear 18. The horizontal movement of the pushing block 31 and the second rack 17 can drive the second gear 18 to rotate.

[0038] An indicating needle 22 is installed at one end of the rotating rod 19 outside the second movable box 14. A scale line 23 is installed on one side of the second movable box 14 close to the indicating needle 22. The position indicated by the indicating needle 22 on the scale line 23 can facilitate the observation of the position of the film pushing piece 21 at this time.

[0039] The size of the inner opening of the second movable box 14 is adapted to the size of the pushing block 31, so that the movement of the pushing block 31 is more stable.

[0040] In this embodiment, when smear preparation of bone marrow cells is required, a glass slide containing bone marrow cells can be placed on the placement plate 1 at this time. Then, turn the turning handle 16. The rotation of the turning handle 16 drives the rotation of the second threaded rod 15. The force generated during the rotation of the second threaded rod 15 can drive the movement of the pushing block 31. When the pushing block 31 moves, it can drive the movement of the second rack 17. Since the second rack 17 meshes with the second gear 18, when the second rack 17 moves, it drives the rotation of the second gear 18. When the second gear 18 rotates, it can drive the rotation of the rotating rod 19. When the rotating rod 19 rotates, it can drive the rotation of the smear 21 through the connecting rod 20, thereby realizing the adjustment of the angle between the smear 21 and the glass slide, ensuring that the smear 21 is at an appropriate angle during operation. And when the rotating rod 19 rotates, it can drive the rotation of the indicating needle 22. The position indicated by the indicating needle 22 on the scale line 23 can facilitate the observation of the position of the smear 21 at this time. Then, the first threaded rod 5 can be rotated. The force generated by the rotation of the first threaded rod 5 drives the first movable box 4 to move downward through the guidance of the square block 3, and at the same time drives the smear 21 to move downward, and then contacts the bone marrow cells on the glass slide, thereby adjusting the contact force so that it forms a line in contact with the smear 21. In this way, the required angle and contact force adjustment can be prepared before the smear preparation work, avoiding uneven force or angle change that may occur during direct pushing, and improving the accuracy of smear preparation.

[0041] Embodiment 2

[0042] As Figures 1 - 9 shown, based on Embodiment 1, a sliding groove 6 is opened in the upper part of the first movable box 4. A guide rod 7 is installed inside the sliding groove 6. A sliding block 8 is slidably arranged inside the sliding groove 6. The sliding block 8 is movably connected to the guide rod 7 to ensure that the sliding block 8 moves along the sliding groove 6 under the guidance of the guide rod 7.

[0043] A first gear 10 is rotatably connected inside the sliding groove 6. A housing 11 is installed on the side of the first movable box 4. A third rack 12 is slidably arranged inside the housing 11. The third rack 12 is fixedly connected to the movable plate 13. Both the third rack 12 and the first rack 9 mesh with the first gear 10. When the third rack 12 moves downward, it can drive the rotation of the first gear 10 and at the same time drive the lateral movement of the first rack 9.

[0044] On the side of the movable block 24 close to the extrusion block 28, a telescopic rod 25 and a spring 26 are installed. The ends of the telescopic rod 25 and the spring 26 away from the movable block 24 are jointly installed with a pressure-receiving block 27. A third threaded rod 29 is slidably arranged inside the sliding block 8. The third threaded rod 29 is threadedly connected to the extrusion block 28. When the third threaded rod 29 rotates to drive the movement of the extrusion block 28, it can squeeze the two pressure-receiving blocks 27.

[0045] The cross-section of the pressure-receiving block 27 is trapezoidal, and the pressure-receiving block 27 is located on the movement track of the third threaded rod 29, which is convenient for being squeezed by the squeezing block 28.

[0046] In this embodiment, after the pushing piece 21 contacts the bone marrow cells on the glass slide, the movable plate 13 can be pressed, driving the third rack 12 to move downward at the same time. Since the third rack 12 meshes with the first gear 10, when the third rack 12 moves downward, it can drive the first gear 10 to rotate. At the same time, the first gear 10 meshes with the first rack 9. When the first gear 10 rotates, it can drive the first rack 9 to move horizontally, driving the sliding block 8 to move along the guide rod 7 at the same time. When the sliding block 8 moves, it can drive the pushing piece 21 to move through the second movable box 14. When the pushing piece 21 moves, it can perform the pushing work on the bone marrow cells on the glass slide. And by pressing, the uniformity of the speed during pushing can be better controlled, avoiding the possible speed changes during direct pushing, ensuring that the cells are evenly distributed on the glass slide, and making cell observation and analysis more accurate.

[0047] When the bone marrow fluid is relatively viscous or the cell density is relatively large, the pushing speed should be appropriately slowed down. On the contrary, when the bone marrow fluid is relatively thin or the cell density is relatively small, the pushing speed can be appropriately increased. When the speed needs to be adjusted, the squeezing block 28 can be rotated. The acting force generated when the squeezing block 28 rotates drives the third threaded rod 29 to move. When the squeezing block 28 moves, it can squeeze the two pressure-receiving blocks 27, causing the two pressure-receiving blocks 27 to move away from each other, and at the same time squeezing the telescopic rod 25 and the spring 26, causing the telescopic rod 25 and the spring 26 to contract. And through the elasticity of the telescopic rod 25 and the spring 26, the movable block 24 is pushed, thereby increasing the force between the rotating wheel 30 and the inner part of the sliding groove 6, increasing the resistance when the pushing piece 21 moves, so as to facilitate controlling the speed when the pushing piece 21 moves for pushing.

[0048] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A bone marrow cell pusher, comprising a placement plate (1), characterized in that: A bottom plate (2) is installed on the side of the placement plate (1), and a first movable box (4) is movably connected to the upper part of the bottom plate (2). A second movable box (14) is slidably installed on the upper part of the first movable box (4), and a connecting rod (20) is rotatably connected to the end of the second movable box (14). A push piece (21) is detachably installed at one end of the connecting rod (20) away from the second movable box (14). A pushing component for the push piece (21) is provided on the first movable box (4), and the pushing component includes a third rack (12) slidably installed on the first movable box (4), a sliding block (8) slidably installed on the inner side of the first movable box (4), a first gear (10) rotatably connected to the inner side of the first movable box (4), and a first rack (9) installed on the side of the sliding block (8); the sliding block (8) is fixedly connected to the second movable box (14), and the third The rack (12) moves downward and drives the first rack (9) to move through the first gear (10). When the first rack (9) moves, it drives the sliding block (8) to move horizontally. When the sliding block (8) moves, it drives the push piece (21) to move on the glass slide on the placement plate (1) through the second movable box (14). The sliding block (8) is provided with a movement resistance adjustment component for the push piece (21). The movement resistance adjustment component includes a movable block (24) symmetrically and movably connected to the outer side of the sliding block (8), a rotating wheel (30) rotatably connected to the inner side of the movable block (24), and a third threaded rod (29) rotatably connected to the inner side of the sliding block (8). When the third threaded rod (29) rotates, it can drive the two movable blocks (24) to move in opposite directions. When the two movable blocks (24) move in opposite directions, the contact force between the rotating wheel (30) and the first movable box (4) can be increased or reduced. The second movable box (14) is provided with an adjustment assembly for the push piece (21), the adjustment assembly comprising a rotating handle (16) rotatably connected to the second movable box (14), a second rack (17) slidably arranged inside the second movable box (14), a second gear (18) rotatably connected inside the second movable box (14), and a rotating rod (19) installed on the side of the second gear (18), the rotating rod (19) and the connecting rod (20) are fixedly connected, when the rotating handle (16) rotates, the second rack (17) is driven to move horizontally, when the second rack (17) moves, the second gear (18) is driven to rotate, and the rotation of the second gear (18) drives the push piece (21) to move in a circular motion through the rotating rod (19) and the connecting rod (20).

2. A bone marrow cell pusher according to claim 1, characterized in that: A square block (3) is installed on the upper part of the bottom plate (2), and the square block (3) is movably connected to the first movable box (4). A first threaded rod (5) is rotatably connected to the upper part of the bottom plate (2), and the first threaded rod (5) is threadedly connected to the first movable box (4).

3. A bone marrow cell pusher according to claim 2, characterized in that: A sliding groove (6) is provided on the upper part of the first movable box (4), a guide rod (7) is installed on the inner side of the sliding groove (6), the sliding block (8) is slidably arranged on the inner side of the sliding groove (6), and the sliding block (8) is movably connected to the guide rod (7).

4. A bone marrow cell pusher according to claim 3, characterized in that: The inner side of the sliding groove (6) is rotatably connected to a first gear (10); the side of the first movable box (4) is provided with an outer shell (11); the third rack (12) is slidably arranged on the inner side of the outer shell (11); the third rack (12) is fixedly connected to the movable plate (13); and the third rack (12) and the first rack (9) are both meshed with the first gear (10).

5. A bone marrow cell pusher according to claim 1, characterized in that: A pushing block (31) is slidably disposed inside the second movable box (14); the pushing block (31) is threadedly connected to the second threaded rod (15); and one end of the second threaded rod (15) away from the pushing block (31) is fixedly connected to the rotating handle (16).

6. A bone marrow cell pusher according to claim 5, characterized in that: The side of the pushing block (31) away from the second threaded rod (15) is fixedly connected to the second rack (17), and the second rack (17) is meshed with the second gear (18).

7. A bone marrow cell pusher according to claim 1, characterized in that: An indicator needle (22) is installed at one end of the rotating rod (19) outside the second movable box (14), and a scale line (23) is installed on one side of the second movable box (14) close to the indicator needle (22).

8. A bone marrow cell pusher according to claim 1, characterized in that: A telescopic rod (25) and a spring (26) are installed on one side of the movable block (24) close to the extrusion block (28); a pressure block (27) is installed together on one end of the telescopic rod (25) and the spring (26) away from the movable block (24); a third threaded rod (29) is slidably arranged on the inner side of the sliding block (8); and the third threaded rod (29) is threadedly connected to the extrusion block (28).

9. A bone marrow cell pusher according to claim 8, characterized in that: The cross section of the pressure block (27) is trapezoidal, and the pressure block (27) is located on the movement track of the third threaded rod (29).

10. A bone marrow cell pusher according to claim 5, characterized in that: The size of the inner opening of the second movable box (14) is adapted to the size of the pushing block (31).

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