Ion-curable hydrogel composition comprising extracellular polysaccharides

Abstract

In accordance with an embodiment of the present invention, a hydrogel composition is provided. The hydrogel composition may include: a first gel; the present invention relates to a gel composition comprising a first gel agent and a second gel agent, the first gel agent comprising at least one of an alginate (Alginate), a carrageenan (Carrageenan) and a gellan gum (Gellan Gum), and the second gel agent being a Succinoglycan (Succino Glycan), the gel composition comprising at least one of the first gel agent and the second gel agent comprising at least one of an alginate (Alginate), a carrageenan (Carrageenan) and a gellan gum (Gum).

Description

Technical Field

[0001] The present invention relates to an ion-curing hydrogel composition containing extracellular polysaccharides, and more particularly, to a hydrogel composition that can prevent dehydration shrinkage and provide an excellent feeling in use by further containing succinoglycan as a second gelling agent in addition to a first gelling agent. Background Art

[0002] A hydrogel is a substance formed by cross-linking hydrophilic polymer chains into a three-dimensional network structure, containing a large amount of water inside, and having unique properties such as being in a thermodynamically stable state in an aqueous solution, and is actively used in various fields such as medicine, beauty, and industry.

[0003] Such a hydrogel contains gelling agents such as carrageenan, cellulose, xanthan gum, etc. to form a firm film. However, conventional hydrogels prepared only using such gelling agents have problems such as dehydration shrinkage in which water separates from the gel, or a slightly heavy feeling in use. Summary of the Invention

[0004] Problems to be Solved by the Invention

[0005] The present invention is for solving the above problems, and an object thereof is to provide a hydrogel composition that contains a large amount of water, minimizes dehydration shrinkage, and has an excellent feeling when applied to the skin and in use.

[0006] The technical problems of the present invention are not limited to the above-mentioned technical problems, and other technical problems not mentioned can be clearly understood by those of ordinary skill in the technical field to which the present invention pertains through the following description.

[0007] Means for Solving the Problems

[0008] According to an embodiment of the present invention, a hydrogel composition is provided. The hydrogel composition may include: a first gelling agent; and a second gelling agent, the first gelling agent includes alginate, carrageenan, and gellan gum, and the second gelling agent may be succinoglycan.

[0009] Moreover, the alginate, the carrageenan, the gellan gum, and the succinoglycan can be included in a weight ratio of 1:0.5 to 8:0.5 to 2:0.5 to 4.

[0010] Moreover, the alginate can be included in the total weight of the composition at 0.01 to 10 weight percent.

[0011] Moreover, the carrageenan can be included in the total weight of the composition at 0.01 to 10 weight percent.

[0012] Moreover, the above-mentioned gellan gum can be included in the total weight of the composition at 0.01 to 10 weight percent.

[0013] Moreover, the above-mentioned succinoglycan can be included in the total weight of the composition at 0.01 to 10 weight percent.

[0014] Moreover, the above-mentioned first gelling agent can include one or more selected from the group consisting of glucomannan, xanthan gum, gelatin, chitosan, collagen, hyaluronic acid, acacia senegal gum, pullulan, pectin, cellulose, sclerotium gum, caesalpinia spinosa gum, agar, locust bean gum, and cyamopsis tetragonoloba (guar) gum.

[0015] Moreover, the present invention may further include at least one of a curing agent and a moisturizing agent.

[0016] Moreover, the above-mentioned curing agent can include at least one of divalent metal ions, trivalent metal ions, and metal salts.

[0017] Moreover, the above-mentioned metal ions can include one or more selected from the group consisting of calcium (Ca 2+ ), magnesium (Mg 2+ ), barium (Ba 2+ ), manganese (Mn 2+ ), nickel (Ni 2 + ), copper (Cu 2+ ), zinc (Zn 2+ ), iron (Fe 3+ ), and aluminum (Al 3+ ).

[0018] Moreover, the above-mentioned metal salts can include one or more selected from the group consisting of calcium chloride, calcium hydroxide, calcium nitrate, and calcium sulfide.

[0019] Moreover, the above-mentioned curing agent can be included in the total weight of the composition at 0.01 to 5 weight percent.

[0020] Furthermore, the above-mentioned humectant may include one or more selected from the group consisting of glycerin, propylene glycol, dipropylene glycol, butylene glycol, pentylene glycol, and sorbitol.

[0021] Furthermore, the above-mentioned humectant may be included in the total weight of the composition at 0.01 to 35 weight percent.

[0022] According to an embodiment of the present invention, there is provided a method for preparing a hydrogel composition. The above method may include: a step of obtaining a mixture by mixing a first gelling agent and a second gelling agent in purified water; and a step of dropping the above mixture into a curing agent, wherein the first gelling agent includes alginate, carrageenan, and gellan gum, and the second gelling agent is succinoglycan.

[0023] Effects of the Invention

[0024] The hydrogel composition according to the present invention has excellent physical properties such as swelling property, wetness, and strength, contains a large amount of moisture inside the gel, and minimizes the evaporation of moisture and the phenomenon of dehydration shrinkage.

[0025] Furthermore, the hydrogel composition according to the present invention has the advantages of being easily applied to the skin and having excellent rolling feeling and residue feeling. Detailed Description of the Invention

[0026] Unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as commonly understood by those of ordinary skill in the technical field to which the present invention belongs. Generally, the nomenclature used in this specification is well-known and commonly used in the technical field. And, in the process of describing the embodiments of the present invention, when it is determined that the specific description of a related well-known structure or function hinders the understanding of the embodiments of the present invention, the detailed description thereof is omitted. And, the embodiments of the present invention will be described below, but the technical idea of the present invention is not limited thereto or restricted thereby, and can be variously implemented by those of ordinary skill in the technical field to which the present invention belongs.

[0027] The present invention relates to a hydrogel composition, and specifically, to a hydrogel composition having excellent physical properties such as swelling property, wetness, or strength, and excellent usability such as rolling feeling or residue feeling.

[0028] The present inventors have developed a hydrogel composition with excellent rolling and residual sensations by using extracellular polysaccharides produced from microorganisms as gelling agents and optimally adjusting the physical properties of hydrogels such as wettability, swelling properties, and strength.

[0029] The hydrogel composition of the present invention may contain two or more gelling agents.

[0030] The gelling agent forms a film in a manner that contains a large amount of water inside and can play a role in adjusting the strength of the hydrogel. Specifically, the gelling agent may contain two gelling agents composed of a first gelling agent and a second gelling agent. When the second gelling agent is also included together with the first gelling agent, the strength of the gel is more stably adjusted, the water content of the gel becomes higher, and excellent moisturizing effects and usability can be provided.

[0031] According to the examples, the first gelling agent may contain at least one of alginate, carrageenan, and gellan gum. For example, the first gelling agent may contain all of alginate, carrageenan, and gellan gum. When alginate, carrageenan, and gellan gum are used in combination as the first gelling agent, the hydrogel can effectively absorb water and minimize the evaporation of the absorbed water.

[0032] For example, alginate may be contained in the total weight of the composition at 0.01 to 10% by weight, specifically, it can be contained at 0.01 to 5% by weight, and more specifically, it can be contained at 0.01 to 1.2% by weight.

[0033] And, for example, carrageenan may be contained in the total weight of the composition at 0.01 to 10% by weight, specifically, it can be contained at 0.01 to 5% by weight, and more specifically, it can be contained at 0.01 to 2% by weight.

[0034] As another example, gellan gum may be contained in the total weight of the composition at 0.01 to 10% by weight, specifically, it can be contained at 0.01 to 5% by weight, and more specifically, it can be contained at 0.01 to 1.2% by weight.

[0035] When alginate, carrageenan, or gellan gum respectively exceeds the above content range, even if a gel is not formed or a gel is formed, the usability may decrease.

[0036] According to an embodiment, the first gelling agent may further include one or more selected from the group consisting of glucomannan, xanthan gum, gelatin, chitosan, collagen, hyaluronic acid, acacia senegal gum, pullulan, pectin, cellulose, sclerotium gum, caesalpinia spinosa gum, agar, locust bean gum, and cyamopsis tetragonoloba (guar) gum, but is not limited thereto.

[0037] According to an embodiment, the second gelling agent, as an exopolysaccharide, may be succinoglycan. Succinoglycan is a polysaccharide produced from the fermentation product of Sinorhizobium meliloti or Agrobacterium tumefaciens, and can, together with the first gelling agent, improve the strength of the hydrogel, prevent the phenomenon of gel collapse, enable the hydrogel to contain more moisture, and minimize the evaporation of moisture from the hydrogel.

[0038] Generally, existing hydrogel compositions only contain the first gelling agent to form a firm film. Such hydrogel compositions have problems such as syneresis, where moisture separates from the gel, or are difficult to apply to the skin and difficult to roll, resulting in poor usability. However, in the present invention, generally, in addition to the first gelling agent used as a gelling agent for the hydrogel, succinoglycan as the second gelling agent is also included, which can minimize the syneresis phenomenon and provide excellent usability such as a smooth application feel when applied to the skin and a moisturizing effect that gives a feeling of persistence when the composition remains on the skin.

[0039] According to an embodiment, succinoglycan may be included in the total weight of the composition at 0.01 to 10% by weight, specifically, it can be included at 0.01 to 5% by weight, and more specifically, it can be included at 0.01 to 1.2% by weight. When succinoglycan is included in the total weight of the composition at less than 0.01% by weight, there may be a syneresis phenomenon of the hydrogel, and when included at more than 10% by weight in the total weight of the composition, the strength of the gel is too high, resulting in a possible gel collapse phenomenon.

[0040] Specifically, in the present invention, for example, the first gelling agent may be alginate, carrageenan, and gellan gum, and the second gelling agent is succinoglycan. The present inventors have confirmed that by forming the first gelling agent and the second gelling agent from the above components, a synergistic effect appears in terms of the physical properties (e.g., swelling property, wetness property, or strength) and the feeling of use of the hydrogel.

[0041] According to the examples, alginate, carrageenan, gellan gum, and succinoglycan can be included in a weight ratio of 1:0.5 to 8:0.5 to 2:0.5 to 4, specifically, can be included in a weight ratio of 1:2 to 6:1 to 2:1 to 4. By adjusting the weight ratio of alginate, carrageenan, gellan gum, and succinoglycan within the above range, the film of the hydrogel is firmly formed, the shape does not collapse, the syneresis phenomenon is minimized, and the feeling of use such as the rolling feeling and the residual feeling can be improved.

[0042] In this way, in the present invention, generally, in addition to the first gelling agent used as the gelling agent of the hydrogel, succinoglycan as the second gelling agent is also included together, so that the physical properties such as the strength, swelling property, and wetness property of the hydrogel containing a large amount of water can be stably adjusted, and the syneresis phenomenon is minimized. And the hydrogel according to the present invention has excellent characteristics such as a rolling feeling and a residual feeling in terms of the feeling of use.

[0043] According to the examples, the hydrogel composition of the present invention may further include at least one of a curing agent and a moisturizing agent.

[0044] The curing agent can play a role in adjusting the curing speed of the gel. Specifically, the curing agent (e.g., metal ions), as a polysaccharide, can form a crosslink with the first gelling agent and the second gelling agent to form a film of the hydrogel.

[0045] According to the examples, the curing agent may include metal ions of divalent or higher, specifically, at least one of divalent metal ions, trivalent metal ions, and metal salts. For example, the divalent metal ions may include one or more selected from the group consisting of calcium (Ca 2+ ), magnesium (Mg 2 + ), barium (Ba 2+ ), manganese (Mn 2+ ), nickel (Ni 2+ ), copper (Cu 2+ ), and zinc (Zn 2+ ), and the trivalent metal ions may include one or more selected from the group consisting of iron (Fe 3+ ) and aluminum (Al 3+ ), but is not limited thereto.

[0046] Further, the metal salt may include, for example, one or more selected from the group consisting of calcium chloride, calcium hydroxide, calcium nitrate, and calcium sulfide, but is not limited thereto.

[0047] According to an embodiment, the curing agent may be included in an amount of 0.01 to 5 wt% based on the total weight of the composition. When the curing agent is included in an amount of less than 0.01 wt% based on the total weight of the composition, the curing time of the gel may be very long. When included in an amount of more than 5 wt% based on the total weight of the composition, the curing is too fast and the moldability may decrease.

[0048] The humectant may serve to provide a moisturizing effect such as supplying moisture to the skin or minimizing moisture evaporation.

[0049] According to an embodiment, the humectant may include one or more selected from the group consisting of glycerin, propylene glycol, dipropylene glycol, butylene glycol, pentylene glycol, and sorbitol, but is not limited thereto.

[0050] According to an embodiment, the humectant may be included in an amount of 0.01 to 35 wt% based on the total weight of the composition, specifically, it can be included in an amount of 0.01 to 30 wt%. When the humectant is included in an amount of less than 0.01 wt% based on the total weight of the composition, the moisturizing effect may be negligible. When included in an amount of more than 35 wt% based on the total weight of the composition, the strength or properties of the hydrogel may not be properly adjusted.

[0051] According to an embodiment, the hydrogel composition of the present invention may further include other components commonly used in the art within the scope that does not impair the effects of the present invention, for example, preservatives, thickeners, pH adjusters, isotonic agents, surfactants, stabilizers, preservatives, ultraviolet absorbers, bactericides, barrier agents, antioxidants, organic pigments, inorganic pigments, fragrances, vitamins, etc. The blending amounts of the above components can be easily selected by those of ordinary skill in the technical field to which the present invention pertains within the scope that does not impair the purpose and effects of the present invention.

[0052] According to an embodiment, the hydrogel composition of the present invention can be prepared into functional cosmetics such as nutritional creams, essences, and serums, or basic cosmetics such as lotions and skin care liquids. In addition, it can also be prepared into soaps, detergents, cleansing creams, makeup removers, etc., or prepared into hair cleaning products such as shampoos, conditioners, hair treatment serums, hair gels, etc. And, for example, it can also be prepared into products attached to the skin such as facial masks and hydrogel slimming patches, or processed into spherical shapes and utilized in the form of capsules.

[0053] The hydrogel composition of the present invention can be prepared by the following method.

[0054] First, a first gelling agent and a second gelling agent can be mixed in purified water to obtain a mixture. According to an embodiment, the first gelling agent may include at least one of alginate, carrageenan, and gellan gum. For example, the first gelling agent may entirely include alginate, carrageenan, and gellan gum. When alginate, carrageenan, and gellan gum are used in combination as the first gelling agent, the hydrogel can effectively absorb water and minimize the evaporation of the absorbed water.

[0055] According to an embodiment, the second gelling agent can be succinoglycan. In general, the present invention can prepare a composition with excellent usability such as minimizing the syneresis phenomenon, providing a soft application feel as if rolling when applied to the skin, and providing a continuous moisturizing effect as if the composition remains on the skin by mixing succinoglycan as the second gelling agent together with the first gelling agent used as the gelling agent of the hydrogel in purified water.

[0056] According to an embodiment, the mixing ratio of the first gelling agent and the second gelling agent can be appropriately adjusted to maximize the physical properties of the hydrogel and the usability of the composition. For example, when the first gelling agent is alginate, carrageenan, and gellan gum, and the second gelling agent is succinoglycan, alginate, carrageenan, gellan gum, and succinoglycan can be mixed in a weight ratio of 1:0.5 to 8:0.5 to 2:0.5 to 4, specifically, in a weight ratio of 1:2 to 6:1 to 2:1 to 4.

[0057] According to an embodiment, in addition to the first gelling agent and the second gelling agent, other components commonly used in the art can also be mixed in purified water within the range that does not impair the effects of the present invention, such as preservatives, thickeners, pH regulators, isotonic agents, surfactants, stabilizers, preservatives, ultraviolet absorbers, bactericides, barrier agents, antioxidants, organic pigments, inorganic pigments, fragrances, vitamins, etc. The blending amounts of the above components can be easily selected by those of ordinary skill in the technical field to which the present invention pertains within the range that does not impair the purpose and effects of the present invention.

[0058] Thereafter, the mixture can be dropped into the curing agent. Thereby, the polymer chains of the mixture can be physically crosslinked and cured into a gel structure. Specifically, as the polysaccharide, the first gelling agent and the second gelling agent can form a crosslink with divalent or higher metal ions such as Ca 2+ ions to form a film of the hydrogel.

[0059] According to the embodiment, the curing agent can include at least one of divalent metal ions, trivalent metal ions, and metal salts. For example, the divalent metal ions can include one or more selected from the group consisting of calcium (Ca 2+ ), magnesium (Mg 2+ ), barium (Ba 2+ ), manganese (Mn 2+ ), nickel (Ni 2 + ), copper (Cu 2+ ), and zinc (Zn 2+ ), and the trivalent metal ions can include one or more selected from the group consisting of iron (Fe 3+ ) and aluminum (Al 3+ ), but are not limited thereto.

[0060] And, for example, the metal salt can include one or more selected from the group consisting of calcium chloride, calcium hydroxide, calcium nitrate, and calcium sulfide, but is not limited thereto.

[0061] According to the embodiment, the dropping of the mixture can be performed by dropping it in a dropwise manner using a syringe pump in an aqueous solution in which the curing agent is dissolved. However, the dropping method of the mixture is not limited thereto, and various methods such as dropping using a pipette, a pipettor, and a burette can be adopted.

[0062] According to the embodiment, in addition to the dropping method, other methods can also be applied to form the mixture into a gel structure. For example, the hydrogel composition can be prepared by a method of pouring the mixture into a mold for molding. In this case, the hydrogel composition can be prepared into a hydrogel soap, a facial mask, a patch, etc.

[0063] And, for example, the hydrogel composition can be prepared by a method of passing through a series of processes such as applying the mixture to a non-woven fabric, attaching it to a release film, or rolling and cutting to prepare it in the form of a patch. In this case, the hydrogel composition can be prepared in the form of a facial mask or the like.

[0064] The hydrogel composition prepared by this method usually contains a first gelling agent used as a gelling agent for the hydrogel and also contains succinoglycan as a second gelling agent, and can firmly form a hydrogel film, minimizing the syneresis phenomenon. Moreover, it has excellent physical properties of hydrogels such as swelling property, wetness, and strength, and maximizes the usability such as rolling feeling and residual feeling.

[0065] [Experimental Example]

[0066] Hereinafter, examples for more specifically illustrating the present invention are shown below, but the present invention is not limited thereto.

[0067] Preparation of Examples and Comparative Examples

[0068] (1) Preparation of Examples 1 to 5

[0069] Examples of the composition according to the present invention were prepared using the components described in Table 1 below. The unit of the component content in Table 1 is weight percentage.

[0070] Examples 1 to 5 are hydrogel compositions in which the weight ratio of the first gelling agent and the second gelling agent is adjusted within the scope of the examples of the present invention.

[0071] Table 1

[0072]

[0073] Specifically, a preservative, a humectant, and a gelling agent were mixed in water and stirred uniformly. Then, the mixture was dropped into an aqueous solution in which a curing agent was dissolved and cured to complete the compositions of Examples 1 to 5.

[0074] (2) Preparation of Comparative Examples 1 to 11

[0075] Comparative examples of the composition according to the present invention were prepared using the components described in Table 2 below. The unit of the component content in Table 2 is weight percentage.

[0076] Comparative examples 1 to 11 are compositions in which at least one of the four components constituting the first gelling agent and the second gelling agent is removed.

[0077] Specifically, a preservative, a humectant, and a gelling agent were mixed in water and stirred uniformly. Then, the mixture was dropped into an aqueous solution in which a curing agent was dissolved and cured to complete the compositions of Examples 1 to 5.

[0078] (2) Preparation of Comparative Examples 1 to 11

[0079] Comparative examples of the composition according to the present invention were prepared using the components described in Table 2 below. The unit of the component content in Table 2 is weight percentage.

[0080] Comparative Examples 1 to 11 are compositions in which at least one of the four components constituting the first gelling agent and the second gelling agent is excluded.

[0081] Table 2

[0082]

[0083] The specific preparation method is the same as that of Examples 1 to 5.

[0084] (3) Preparation of Comparative Examples 12 to 15

[0085] Comparative examples of the composition according to the present invention were prepared using the components described in Table 3 below. The unit of the component content in Table 3 is weight percentage.

[0086] Comparative Examples 12 to 15 are compositions in which the ratio of the first gelling agent and the second gelling agent is adjusted outside the scope of the examples of the present invention.

[0087] Table 3

[0088]

[0089] The specific preparation method is the same as that of Examples 1 to 5.

[0090] Experimental Examples

[0091] (1) Experimental Example 1: Physical Property Evaluation of Hydrogel

[0092] Regarding the compositions of Examples 1 to 5 and Comparative Examples 1 to 15 above, as physical property evaluations of the hydrogel, swelling property, wetting property, and strength, the results are shown in Table 4.

[0093] The experimental method is as follows. Regarding the swelling property, after immersing the samples of the examples and comparative examples in water at the same weight, the swelling property was evaluated by measuring the degree of change in weight. The more the weight increases after immersion in water, the more water the hydrogel absorbs, and it can be evaluated that the swelling property is more excellent.

[0094] Regarding the wetting property, after exposing the samples of the examples and comparative examples to the outside for 24 hours, the wetting property was evaluated by measuring the degree of water evaporation. The lower the absolute value of the measured (-) value, the less the water evaporation amount of the hydrogel, and it can be evaluated that the wetting property is more excellent.

[0095] Regarding the strength, a RHEOTECH FUDOH RHEO METER RTC-3005D was used as a rheometer to measure the strength of the hydrogel. When the strength is very high and exceeds the specified value, the hydrogel is likely to break. Therefore, when the strength is 20 or less, the hydrogel is firm, and it can be evaluated that the properties of the hydrogel are excellent.

[0096] Table 4

[0097]

[0098] According to the experimental results, in Examples 1 to 5, the swelling properties were all measured to be values of 20 or more, the absolute value of the wettability was measured to be a value of 30 or less, and the strength was measured to be a value of 20 or less. It can be seen that the swelling property, wettability, and strength of the hydrogel are very excellent.

[0099] On the other hand, in Comparative Examples 1 to 11 in which one or more of the components constituting the first gelling agent and the second gelling agent were excluded, the swelling property was measured to be a value less than 20, or the absolute value of the wettability was measured to be a value greater than 30, or the strength was measured to be a value greater than 20. It was confirmed that at least one of the physical properties of the swelling property, wettability, and strength of the hydrogel was poor.

[0100] Moreover, in Comparative Examples 12 to 15 in which the weight ratio of the first gelling agent and the second gelling agent exceeded the range of the examples, the swelling property was measured to be a value less than 20, or the absolute value of the wettability was measured to be a value greater than 30, or the strength was measured to be a value greater than 20. It was confirmed that at least one of the physical properties of the swelling property, wettability, and strength of the hydrogel was poor.

[0101] (2) Experimental Example 2: Evaluation of usability

[0102] In order to evaluate the usability of the compositions according to Examples 1 to 5 and Comparative Examples 1 to 15 above, 30 evaluators in their 20s to 40s were each required to evaluate the items of rolling feeling and residual feeling, and the results are shown in Table 5.

[0103] The experimental method is as follows. After applying the samples of the above examples and comparative examples to the skin of the evaluators, in the evaluation items, the feelings were evaluated on a 5-point scale as the evaluation scale, with the score being a full score of 5 points and assigned in units of 1 point by stage. The usability was evaluated by the value excluding the deviation after calculating the average value of the total scores.

[0104] Table 5

[0105]

[0106]

[0107] According to the experimental results, in Examples 1 to 5, the scores of the rolling feeling and residual feeling items were both evaluated to be relatively high, and it can be seen that they have excellent usability.

[0108] On the other hand, in Comparative Examples 1 to 11 in which one or more of the components constituting the first gelling agent and the second gelling agent were excluded, the scores of the rolling feeling and residual feeling items were both evaluated to be relatively low, and it was confirmed that the usability was poor.

[0109] Moreover, in Comparative Examples 12 to 15 where the weight ratios of the first and second gelling agents exceeded the ranges of the examples, the scores for the items of rolling feeling and residual feeling were also evaluated as low, confirming poor usability.

[0110] As described above, specific parts of the content of the present invention have been described in detail. For those of ordinary skill in the art to which the present invention pertains, such specific descriptions are merely preferred embodiments, and it is obvious that the scope of the present invention is not limited thereto. Therefore, the substantial scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A hydrogel composition, characterized in that, Comprising: A first gelling agent; and A second gelling agent, The first gelling agent comprises alginate, carrageenan and gellan gum, The second gelling agent is succinoglycan.

2. The hydrogel composition according to claim 1, wherein The above-mentioned alginate, the above-mentioned carrageenan, the above-mentioned gellan gum and the above-mentioned succinoglycan are included in a weight ratio of 1:0.5 to 8:0.5 to 2:0.5 to 4.

3. The hydrogel composition according to claim 1, characterized in that, The above-mentioned alginate is included in the total weight of the composition at 0.01 to 10% by weight.

4. The hydrogel composition according to claim 1, characterized in that, The above-mentioned carrageenan is included in the total weight of the composition at 0.01 to 10% by weight.

5. The hydrogel composition according to claim 1, wherein The above-mentioned gellan gum is included in the total weight of the composition at 0.01 to 10% by weight.

6. The hydrogel composition according to claim 1, characterized in that, The above-mentioned succinoglycan is included in the total weight of the composition at 0.01 to 10% by weight.

7. The hydrogel composition according to claim 1, wherein The first gelling agent further comprises one or more selected from the group consisting of glucomannan, xanthan gum, gelatin, chitosan, collagen, hyaluronic acid, gum arabic, pullulan, pectin, cellulose, scleroglucan, tara gum, agar, locust bean gum and guar gum.

8. The hydrogel composition according to claim 1, wherein It further comprises at least one of a curing agent and a humectant.

9. The hydrogel composition according to claim 8, characterized in that, The above-mentioned curing agent comprises at least one of divalent metal ions, trivalent metal ions and metal salts.

10. The hydrogel composition according to claim 9, wherein The above metal ions include one or more selected from the group consisting of calcium (Ca 2 + ), magnesium (Mg 2+ ), barium (Ba 2+ ), manganese (Mn 2+ ), nickel (Ni 2+ ), copper (Cu 2+ ), zinc (Zn 2+ ), iron (Fe 3+ ) and aluminum (Al 3+ ).

11. The hydrogel composition according to claim 9, wherein The above-mentioned metal salts comprise one or more selected from the group consisting of calcium chloride, calcium hydroxide, calcium nitrate and calcium sulfide.

12. The hydrogel composition according to claim 8, wherein The above-mentioned curing agent is included in the total weight of the composition at 0.01 to 5% by weight.

13. The hydrogel composition according to claim 8, characterized in that, The above-mentioned humectant comprises one or more selected from the group consisting of glycerol, propylene glycol, dipropylene glycol, butylene glycol, pentylene glycol and sorbitol.

14. The hydrogel composition according to claim 8, wherein The above-mentioned humectant is included in the total weight of the composition at 0.01 to 35% by weight.

15. A method for preparing a hydrogel composition, characterized in that, Including: The step of mixing the first gelling agent and the second gelling agent in purified water to obtain a mixture; And The step of dropping the above-mentioned mixture into the curing agent, The first gelling agent comprises alginate, carrageenan and gellan gum, The second gelling agent is succinoglycan.

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