Memory alloy pump and insulin pump system thereof

Abstract

The invention relates to the technical field of medical instruments, in particular to a memory alloy pump and an insulin pump system thereof. The memory alloy pump comprises an upper shell, a lower shell, a memory alloy wire and a power supply; according to the principle that the length of the memory alloy wire is shortened when the memory alloy wire is electrified, power for pushing liquid medicine downwards is provided for the memory alloy pump, and the memory alloy pump is small in size, simple in structure and convenient to carry. The insulin pump system comprises a liquid storage structure, a memory alloy pump, an infusion structure and a micro-processing unit; the micro-processing unit comprises a calculation subunit and a control subunit, the calculation subunit can calculate the power-on time of the memory alloy pump according to input human body blood sugar data and send the power-on time to the control subunit, and the control subunit controls the pump to be powered on according to the power-on time. The purpose of automatically and quantitatively injecting insulin according to the requirement of a patient for insulin is achieved, and the problem that an existing insulin pump cannot automatically inject insulin according to the blood sugar content of a human body is solved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a shape memory alloy pump and an insulin pump system thereof. Background Art

[0002] With the development of social economy and the improvement of people's living standards, the incidence of diabetes is increasing continuously. In order to control diabetes (blood sugar), many patients choose to inject insulin to maintain the stability of blood sugar in the body. At present, there are two ways to inject insulin: manual self-injection before meals and automatic injection with an insulin pump. Using an insulin pump to inject insulin has the following advantages: First, the insulin pump can simulate the secretion mode under the normal physiological state of the human body, which is more flexible and reasonable; Second, the dosage of the insulin pump is smaller than the total daily dosage of manual self-injection, and it can control blood sugar more quickly and stably; Third, the insulin pump can avoid multiple subcutaneous injections and reduce the pain of injection.

[0003] However, most of the existing commercial insulin pumps are mechanical pumps, which are relatively large in size and not convenient to carry. Moreover, the existing insulin pumps have relatively high requirements for users, and patients need to keep measuring blood sugar and use the insulin pump reasonably according to the monitoring results, which is not user-friendly for some patients who are unable to move independently. Therefore, there is an urgent need for an insulin pump that can automatically inject insulin according to the blood sugar content of the human body. Summary of the Invention

[0004] The present invention solves the problems that the existing insulin pumps are large in size and not convenient to carry, and that the existing insulin pumps cannot automatically inject insulin according to the blood sugar content of the human body, and provides a shape memory alloy pump and an insulin pump system thereof. The insulin pump system is small in size, simple in structure, convenient to carry, and can automatically inject insulin quantitatively according to the blood sugar content of the human body.

[0005] The technical solutions claimed by the present invention are as follows:

[0006] A memory alloy pump includes an upper housing, a lower housing, memory alloy wires, and a power source; the upper housing is attached to the upper part of the lower housing; the lower housing is a box-shaped structure without a lid on the upper part; a partition with a round hole in the middle is horizontally arranged inside the lower housing, dividing the lower housing into upper and lower parts, and a number of tapered holes with a smaller diameter downward are evenly distributed around the round hole of the partition; a polymer film made of an elastic material covering the round hole is pasted above the middle round hole of the partition; a liquid drug storage cavity is formed between the upper side of the partition and the upper housing; a liquid drug administration cavity is formed between the lower side of the partition and the bottom wall of the lower housing; the upper housing and the lower housing are made of 3D printing resin material; through holes for tightly fitting through the memory alloy wires are respectively arranged at the middle positions of the polymer film and the bottom wall of the lower housing; the memory alloy wires pass through the polymer film and the lower housing in sequence through the through holes of the polymer film and the bottom wall of the lower housing, and both ends of the memory alloy wires are fixed on the polymer film and the bottom wall of the lower housing respectively; both ends of the memory alloy wires are electrically connected to the power source through wires; a hose is connected to the lower side of the bottom wall of the lower housing, and a through hole with the same inner diameter as the hose is arranged at the connection of the lower housing and the hose through the bottom wall of the lower housing; the amount of liquid drug flowing into the hose per unit time of the memory alloy pump can be obtained by estimation.

[0007] Preferably, the elastic material is polytetrafluoroethylene, polydimethylsiloxane, polyacrylate, silica gel, rubber, latex, or polyurethane.

[0008] Preferably, the through hole arranged on the bottom wall of the lower housing has the same diameter as the memory alloy wire; a knot is made at the connection of the memory alloy wire and the polymer film; the memory alloy wire is a nickel-titanium-based shape memory alloy, a copper-based shape memory alloy, or an iron-based shape memory alloy; the nickel-titanium-based shape memory alloy includes Ni-Ti-Cu, Ni-Ti-Co, Ni-Ti-Fe, Ni-Ti-Nb; the copper-based shape memory alloy includes Cu-Zn, Cu-Zn-Al, Cu-Zn-Sn, Cu-Zn-Si, Cu-Zn-Ga, Cu-Sn; the iron-based shape memory alloy includes Fe-Pt, Fe-Mn-Si, Fe-Ni-Co-Ti, Fe-Mn-Al-Ni, Fe-C-Mn-Si-Cr-Ni.

[0009] Preferably, a liquid inlet penetrating the top wall is arranged on the top wall of the upper housing, and a rubber stopper is arranged at the liquid inlet; the connection between the upper housing and the lower housing, and the connections between the memory alloy wires and the polymer film and the lower housing are sealed with sealant.

[0010] Preferably, the working voltage of the memory alloy pump is 1 - 10V, and the working current is 0.1 - 1A; it can be powered on and off 1 - 30 times in 1 minute.

[0011] The amount of liquid medicine flowing into the hose per unit time by the shape memory alloy pump can be estimated in the following way:

[0012] V = (1 / 3)πR 2 H

[0013] Wherein, H is the deformation of the shape memory alloy, and R is the radius of the middle round hole of the partition plate.

[0014] The present invention provides a manufacturing method of the above-mentioned shape memory alloy pump, including the following steps:

[0015] S1: Manufacture the upper housing, and print the upper housing by 3D printing technology;

[0016] S2: Manufacture the lower housing, and print the lower housing by 3D printing technology;

[0017] S3: Manufacture the polymer membrane, and the polymer membrane is made of polytetrafluoroethylene, polydimethylsiloxane, polyacrylate, silica gel, rubber, latex or polyurethane materials;

[0018] S4: Paste the polymer membrane above the middle round hole of the partition plate, and the polymer membrane is set not to cover the surrounding round holes;

[0019] S5: Through holes are respectively arranged at the middle positions of the polymer membrane, the upper wall of the upper housing, and the bottom wall of the lower housing; the shape memory alloy wire passes through the polymer membrane and the bottom wall of the lower housing from top to bottom in sequence; the through holes of the polymer membrane and the bottom wall of the lower housing are tightly adapted to the shape memory alloy wire; a knot is tied at the connection of the shape memory alloy wire and the polymer membrane; a knot is tied at the connection of the shape memory alloy wire and the bottom wall of the lower housing; both ends of the shape memory alloy wire are connected with wires, and the wire connected to the end of the shape memory alloy wire close to the polymer membrane passes through the through hole of the upper wall of the upper housing, and the through hole of the upper wall of the upper housing is tightly adapted to the wire;

[0020] S6: Assemble the shape memory alloy pump, and seal the connection between the upper housing and the lower housing, the connection between the shape memory alloy wire and the polymer membrane and the lower housing, and the connection between the wire and the upper housing with sealant; both ends of the wire are connected to a power source.

[0021] The present invention provides an insulin pump system, which includes a liquid storage structure for storing insulin, a shape memory alloy pump for receiving the liquid storage structure and driving the downward output of insulin, and an infusion structure for receiving the insulin output by the shape memory alloy pump and injecting it into the human body, which are connected in sequence from top to bottom; it further includes a microprocessing unit connected to the shape memory alloy pump; the microprocessing unit includes a calculation subunit for automatically inputting human blood glucose data, calculating the energization time of the shape memory alloy pump according to the blood glucose data and sending the energization time, and a control subunit for receiving the energization time sent by the calculation subunit and controlling the energization and de-energization of the shape memory alloy pump according to the energization time; the shape memory alloy pump is connected to the control subunit; the liquid storage structure is internally provided with an alarm module for alarming when the liquid level is lower than a certain position.

[0022] Preferably, the insulin pump system further includes a blood glucose detection unit connected to the calculation subunit of the microprocessing unit, and the blood glucose detection unit is used for detecting human blood glucose data; the blood glucose detection unit is internally provided with a conventional insulin measuring instrument.

[0023] Preferably, the liquid storage structure is connected to the liquid inlet of the shape memory alloy pump; the concentration of insulin in the liquid storage structure is 1-500 U / ml.

[0024] Beneficial effects:

[0025] The present invention provides a shape memory alloy pump. Through holes for tightly fitting and passing through the shape memory alloy wire are respectively provided at intermediate positions between the polymer membrane and the bottom wall of the lower housing. The shape memory alloy wire passes through the polymer membrane and the bottom wall of the lower housing through the through holes of the polymer membrane and the bottom wall of the lower housing in sequence, and both ends of the shape memory alloy wire are fixed on the polymer membrane and the bottom wall of the lower housing respectively. Both ends of the shape memory alloy wire are electrically connected to the power supply through wires. When the shape memory alloy pump is energized, the length of the shape memory alloy wire will become shorter. The lower housing connected to the shape memory alloy wire is made of 3D printing resin material and is not easily deformed, while the polymer membrane is made of an elastic material and is easily stretched and deformed. Therefore, when the length of the shape memory alloy wire becomes shorter when it is energized, the shape memory alloy wire will pull the polymer membrane to move downward close to the bottom wall of the lower housing. At this time, if there is liquid medicine in the liquid medicine dosing cavity, it will push the liquid medicine to flow downward through the hose connected to the bottom wall of the lower housing. At the same time, liquid medicine can be continuously added to the liquid medicine storage cavity, and the liquid medicine will flow into the liquid medicine dosing cavity through several small holes around the polymer membrane to complete the replenishment of the liquid medicine; when the shape memory alloy pump is energized, the liquid medicine flows into the hose. The amount of liquid medicine flowing into the hose per unit time of the shape memory alloy pump can be estimated, which is convenient for subsequent use of the shape memory alloy pump to realize insulin injection and can perform automatic quantitative drug delivery according to the patient's own situation. The overall design of the shape memory alloy pump is simple, and the volume is small, which is convenient for carrying.

[0026] The through holes provided on the bottom wall of the lower housing have the same diameter as the shape memory alloy wire, so that the through holes just hold the shape memory alloy wire, playing a role in fixing the shape memory alloy wire; a knot is tied at the connection of the shape memory alloy wire and the polymer film, and the shape memory alloy wire passes through the polymer film, and the knotted part is stuck on one side of the polymer film, playing a role in fixing the shape memory alloy wire.

[0027] A liquid inlet penetrating the top wall is provided on the top wall of the upper housing, and liquid medicine can be directly injected into the liquid medicine storage cavity through the liquid inlet to complete the replenishment of the medicine.

[0028] After the shape memory alloy pump is assembled, the connection between the upper housing and the lower housing, the connection between the shape memory alloy wire and the polymer film and the lower housing, and the connection between the wire and the upper housing are sealed with sealant to make the components hermetically connected to ensure the best drug delivery effect.

[0029] The present invention also provides an insulin pump system, including a liquid storage structure, the shape memory alloy pump, an infusion structure, and a microprocessing unit; the microprocessing unit includes a calculation sub-unit that is sequentially connected for automatically inputting human blood glucose data, calculating the energization time of the shape memory alloy pump according to the blood glucose data and sending the energization time, and a control sub-unit that receives the energization time sent by the calculation sub-unit and controls the energization and de-energization of the shape memory alloy pump according to the energization time. The calculation sub-unit can determine the amount of insulin required by the human body according to the input human blood glucose data, calculate the energization time of the shape memory alloy pump through the amount of insulin, and send the energization time to the control sub-unit. The control sub-unit controls the energization of the pump according to the energization time, so as to achieve the purpose of quantitatively injecting insulin according to the patient's demand for insulin, and solve the problem that the existing insulin pump cannot automatically inject insulin according to the human blood glucose content; the liquid storage structure is internally provided with an alarm module, and the alarm module is used for alarming. When the liquid level in the liquid storage structure is lower than a certain position, an alarm is given to remind the user to replenish insulin in time to prevent the harm caused by air injection into the human body due to untimely replenishment of insulin; the shape memory alloy pump is the core component of the insulin pump system. The shape memory alloy pump has a simple structure and a small volume. Therefore, the insulin pump system designed by the shape memory alloy pump has a small volume, a simple structure, is easy to carry, and has a relatively low production cost, solving the problem that the existing insulin pump is large in volume and inconvenient to carry. Description of the Drawings

[0030] Figure 1 It is a schematic structural diagram of the shape memory alloy pump.

[0031] Figure 2 It is a top view of the upper housing and the lower housing of the shape memory alloy pump after being assembled.

[0032] Figure 3 It is a partial view of the partition in the lower housing of the shape memory alloy pump.

[0033] Figure 4 It is a schematic diagram of the relaxed state of the polymer membrane when the shape memory alloy pump is not powered on.

[0034] Figure 5 It is a schematic diagram of the stretched state of the polymer membrane when the shape memory alloy pump is powered on.

[0035] Figure 6 It is a schematic structural diagram of the insulin pump system.

[0036] In the figure, 1 is the upper housing; 2 is the lower housing; 3 is the shape memory wire; 4 is the power supply; 5 is the tapered hole; 6 is the polymer membrane; 7 is the liquid inlet. Specific embodiments

[0037] The present invention will be further described below with reference to the accompanying drawings:

[0038] A shape memory alloy pump, as Figure 1 shown, includes an upper housing, a lower housing, a shape memory alloy wire and a power supply; the upper housing is fitted to the upper part of the lower housing and is sealed with sealant during installation; the lower housing is a box-like structure without a lid on the upper part; as Figure 3 shown, a partition with a round hole in the middle and separating the lower housing into upper and lower parts is horizontally arranged inside the lower housing, and a number of tapered holes with decreasing diameters downward are evenly distributed around the round hole of the partition. In some embodiments of the present invention, the number of the tapered small holes is 4; a polymer membrane made of elastic material covering the round hole is pasted above the middle round hole of the partition; a liquid medicine storage cavity is formed between the upper side of the partition and the upper housing; a liquid medicine administration cavity is formed between the lower side of the partition and the bottom wall of the lower housing; the upper housing and the lower housing are made of 3D printing resin material; through holes for fitting the shape memory alloy wire tightly are respectively arranged at the middle positions between the polymer membrane and the bottom wall of the lower housing; the shape memory alloy wire passes through the polymer membrane and the bottom wall of the lower housing in sequence through the through holes of the polymer membrane and the bottom wall of the lower housing, and both ends of the shape memory alloy wire are fixed on the polymer membrane and the bottom wall of the lower housing respectively; in a specific embodiment of the present invention, a knot is made at the connection of the shape memory alloy wire and the polymer membrane; the knotted part is stuck on one side of the polymer membrane, playing a role in fixing the shape memory alloy wire.

[0039] In a specific embodiment of the present invention, the diameter of the through-hole provided on the bottom wall of the lower housing is the same as that of the shape memory alloy wire. After the shape memory alloy wire passes through the bottom wall of the lower housing, it is just stuck, which plays a role in fixing the shape memory alloy wire. In some other embodiments of the present invention, a knot is tied at the connection of the shape memory alloy wire and the bottom wall of the lower housing. The shape memory alloy wire passes through the bottom wall of the lower housing, and the knotted part is stuck on one side of the bottom wall of the lower housing, which plays a role in fixing the shape memory alloy wire.

[0040] The connection between the shape memory alloy wire and the polymer film and the bottom wall of the lower housing is sealed with a sealant. Both ends of the shape memory alloy wire are electrically connected to the power source through wires. In a specific embodiment of the present invention, through-holes for tightly fitting the wires are provided on the top wall of the upper housing. The wires pass through the through-holes provided on the top wall of the upper housing and are connected to the power source. The through-holes on the upper wall of the upper housing are tightly adapted to the wires. A hose is connected to the lower side of the bottom wall of the lower housing. A through-hole with the same inner diameter as the hose and passing through the bottom wall of the lower housing is provided at the connection between the lower housing and the hose. Liquid medicine is loaded into the liquid medicine storage cavity, and the liquid medicine flows into the liquid medicine administration cavity through the conical hole. When the shape memory alloy pump is powered on, the liquid medicine flows into the hose. The amount of liquid medicine flowing into the hose per unit time by the shape memory alloy pump can be obtained by estimation.

[0041] As Figure 5 shown, after the shape memory alloy wire is powered on, its length shortens, pulling the polymer film to move downward to form a cone, and pushing the liquid in the lower chamber to move outward. As Figure 4 shown, when the shape memory alloy wire is powered off, the length of the shape memory alloy wire becomes longer. The amount of liquid medicine flowing into the hose per unit time by the shape memory alloy pump can be estimated in the following way:

[0042] V = (1 / 3)πR 2 H

[0043] where H is the deformation amount of the shape memory alloy, and R is the radius of the middle circular hole of the partition. In a specific embodiment of the present invention, the diameter R (i.e., the diameter of the polymer film) of the middle circular hole of the partition is 2 cm. When the working voltage of the shape memory alloy pump is 1.5 V and the working current is 0.1 A, after being powered on once, the deformation amount H of the shape memory alloy is 10%. Substituting into the above formula, the amount of liquid medicine flowing into the hose by the shape memory alloy wire after being powered on once is calculated to be 0.04 ml.

[0044] The present invention verifies the above calculation results. The working voltage of the shape memory alloy pump is 1.5V, and the working current is 0.1A. The liquid flows out through a hose connected to the bottom of the pump. By measuring the height of the liquid column flowing out of the tube and the inner diameter of the tube, the volume of the liquid flowing out of the pump during one power-on and power-off cycle can be obtained. In a specific embodiment of the present invention, the inner diameter of the hose is 0.15 cm. The bottom area S of the liquid column can be calculated through the inner diameter of the hose. Through the height value Δh of the liquid column, the amount of liquid flowing out during one power-on and power-off process (SΔh) can be calculated. After 5 measurements, the average value of Δh is 0.4 cm, and the volume of the liquid flowing out of the pump during one power-on and power-off cycle is calculated to be about 0.03 ml, which is generally consistent with the result calculated by the above formula. The difference between the two is theoretically acceptable, and the volume of the liquid flowing out of the pump per minute can be directly determined through the above formula.

[0045] Therefore, when the diameter of the polymer membrane is 2 cm, one shape memory alloy wire undergoes one power-on and power-off cycle (1.5V, 1 s), and in the case of 30 power-on and power-off cycles per minute, the flow rate of the pump with a single shape memory alloy wire can be estimated to be about 1 mL / min.

[0046] Assuming that the liquid compressed by the membrane is a quadrangular pyramid, the height is obtained as 0.025 cm, and the length of the shape memory alloy (i.e., the height of the pump) is 0.4 cm. The deformation rate can be obtained as approximately 6.25% (0.025 / 0.4). By comparing the direct power-on and power-off treatment of the shape memory alloy, the deformation rate is approximately in the order of 10%. It can be found that the shape memory alloy of this pump is basically fully stretched, and most of the tensile force is used to cause the membrane to deform and push the liquid.

[0047] In other embodiments of the present invention, by changing the diameter of the polymer membrane, the same effect can be achieved.

[0048] Both ends of the shape memory alloy wire are electrically connected to the power supply. When the shape memory alloy pump is not powered on, the shape memory alloy is in a relatively long relaxed state, and the polymer membrane connected thereto is in a normal relaxed state. When powered on, the shape memory alloy contracts and its length becomes shorter. Since the lower housing connected to the shape memory alloy wire is made of plastic material and is not easily deformed, while the polymer membrane material is an elastic material and is easily stretched and deformed. Therefore, when the length of the shape memory alloy wire becomes shorter during power-on, the shape memory alloy wire will pull the polymer membrane to move downward close to the bottom wall of the lower housing. At this time, if there is liquid medicine in the liquid medicine administration cavity, it will push the liquid medicine to flow downward through the hose connected to the bottom wall of the lower housing. In order to ensure sufficient drug delivery, the user can continuously add liquid medicine to the liquid medicine storage cavity, and the liquid medicine will flow into the liquid medicine administration cavity through the conical small holes around the polymer membrane to complete the replenishment of the liquid medicine. As Figure 2As shown, a liquid inlet penetrating the top wall is provided on the top wall of the upper housing, and a rubber plug is provided at the liquid inlet. The liquid medicine in the liquid medicine storage cavity can be replenished from the outside through the liquid inlet.

[0049] The elastic material is polytetrafluoroethylene (Teflon), polydimethylsiloxane (PDMS), polyacrylate, silica gel (such as Ecoflex, Dragon Skin), rubber (such as NBR, IIR), latex or polyurethane.

[0050] The shape memory alloy wire can be of three types: nickel-titanium-based shape memory alloy (Ni-Ti SMA), copper-based shape memory alloy (Cu SMA), and iron-based shape memory alloy (Fe SMA). Among them, the nickel-titanium-based shape memory alloy includes memory alloys with high practical value such as Ni-Ti-Cu, Ni-Ti-Co, Ni-Ti-Fe, Ni-Ti-Nb, etc.; the copper-based shape memory alloy mainly includes types such as Cu-Zn, Cu-Zn-Al, Cu-Zn-Sn, Cu-Zn-Si, Cu-Zn-Ga, Cu-Sn, etc.; the iron-based shape memory alloy mainly includes types such as Fe-Pt, Fe-Mn-Si, Fe-Ni-Co-Ti, Fe-Mn-Al-Ni, Fe-C-Mn-Si-Cr-Ni, etc.

[0051] The manufacturing method of the above-mentioned shape memory alloy pump includes:

[0052] S1: Manufacturing the upper housing by 3D printing technology to print the upper housing;

[0053] S2: Manufacturing the lower housing by 3D printing technology to print the lower housing;

[0054] S3: Manufacturing the polymer membrane, and the polymer membrane is made of polytetrafluoroethylene, polydimethylsiloxane, polyacrylate, silica gel, rubber, latex or polyurethane material;

[0055] S4: The polymer membrane is pasted above the middle circular hole of the partition board, and the polymer membrane is set not to cover the surrounding circular small holes;

[0056] S5: Through holes are respectively provided at the middle positions of the polymer membrane, the upper wall of the upper housing, and the bottom wall of the lower housing; the shape memory alloy wire passes through the polymer membrane and the bottom wall of the lower housing from top to bottom in sequence; the through holes of the polymer membrane and the bottom wall of the lower housing are tightly adapted to the shape memory alloy wire; a knot is tied at the connection of the shape memory alloy wire and the polymer membrane; a knot is tied at the connection of the shape memory alloy wire and the bottom wall of the lower housing; both ends of the shape memory alloy wire are connected with wires, and the wire connected to the end of the shape memory alloy wire close to the polymer membrane passes through the through hole of the upper wall of the upper housing, and the through hole of the upper wall of the upper housing is tightly adapted to the wire;

[0057] S6: Assemble the shape memory alloy pump. At the connection between the upper housing and the lower housing, at the connection between the shape memory alloy wire and the polymer film and the lower housing, and at the connection between the wire and the upper housing, sealant is used for sealing; both ends of the wire are connected to a power source.

[0058] An insulin pump system, as Figure 6 shown, includes a liquid storage structure for storing insulin, a shape memory alloy pump as claimed in claim 6 for receiving the liquid storage structure and driving the insulin to output downward, and an infusion structure for receiving the insulin output by the shape memory alloy pump and injecting it into the human body, which are connected in sequence from top to bottom; it further includes a microprocessing unit connected to the shape memory alloy pump; the microprocessing unit includes a calculation sub-unit for automatically inputting human blood glucose data, calculating the energization time of the shape memory alloy pump according to the blood glucose data and sending the energization time, and a control sub-unit for receiving the energization time sent by the calculation sub-unit and controlling the energization and de-energization of the shape memory alloy pump according to the energization time; the shape memory alloy pump is connected to the control sub-unit; the liquid storage structure is internally provided with an alarm module for alarming when the liquid level is lower than a certain position; the liquid storage structure is connected to the liquid inlet of the shape memory alloy pump; the concentration of insulin in the liquid storage structure is 1 - 500 U / ml.

[0059] In some embodiments of the present invention, the insulin pump system further includes a blood glucose detection unit connected to the calculation sub-unit of the microprocessing unit, and the blood glucose detection unit is used for detecting human blood glucose data; the blood glucose detection unit is internally provided with a conventional insulin measuring instrument.

Claims

1. A shape memory alloy pump, characterized in that, It includes an upper shell, a lower shell, a shape memory alloy wire and a power source; the upper shell is fitted to the upper part of the lower shell; the lower shell is a box-shaped structure without a lid on the upper part; inside the lower shell, a partition with a round hole in the middle and separating the lower shell into upper and lower parts is horizontally arranged, and several conical holes with a decreasing diameter downward are evenly distributed around the round hole of the partition; a polymer film made of an elastic material covering the round hole is pasted above the round hole in the middle of the partition; a liquid medicine storage cavity is formed between the upper side of the partition and the upper shell; a liquid medicine administration cavity is formed between the lower side of the partition and the bottom wall of the lower shell. The upper shell and the lower shell are made of 3D printing resin material; through holes for tightly fitting the shape memory alloy wire are respectively arranged at the middle positions of the polymer film and the bottom wall of the lower shell; the shape memory alloy wire passes through the polymer film and the lower shell in sequence through the through holes of the polymer film and the bottom wall of the lower shell, and both ends of the shape memory alloy wire are respectively fixed on the polymer film and the bottom wall of the lower shell; both ends of the shape memory alloy wire are electrically connected to the power source through wires; a hose is connected to the lower side of the bottom wall of the lower shell, and a through hole with the same inner diameter as the hose and penetrating the bottom wall of the lower shell is arranged at the connection between the lower shell and the hose; the amount of liquid medicine flowing into the hose per unit time of the shape memory alloy pump can be obtained through estimation.

2. The shape memory alloy pump according to claim 1, characterized in that, The elastic material is polytetrafluoroethylene, polydimethylsiloxane, polyacrylate, silica gel, rubber, latex or polyurethane.

3. The shape memory alloy pump according to claim 2, wherein, The through hole arranged on the bottom wall of the lower shell has the same diameter as the shape memory alloy wire; a knot is tied at the connection of the shape memory alloy wire and the polymer film; the shape memory alloy wire is a nickel-based shape memory alloy, a copper-based shape memory alloy or an iron-based shape memory alloy; the nickel-based shape memory alloy includes Ni-Ti-Cu, Ni-Ti-Co, Ni-Ti-Fe, Ni-Ti-Nb; the copper-based shape memory alloy includes Cu-Zn, Cu-Zn-Al, Cu-Zn-Sn, Cu-Zn-Si, Cu-Zn-Ga, Cu-Sn; the iron-based shape memory alloy includes Fe-Pt, Fe-Mn-Si, Fe-Ni-Co-Ti, Fe-Mn-Al-Ni, Fe-C-Mn-Si-Cr-Ni.

4. The memory alloy pump according to claim 3, wherein A liquid inlet penetrating the top wall is arranged on the top wall of the upper shell, and a rubber plug is arranged at the liquid inlet; the connection between the upper shell and the lower shell, and the connections between the shape memory alloy wire and the polymer film and the lower shell are sealed with sealant.

5. The memory alloy pump according to claim 4, wherein The working voltage of the shape memory alloy pump is 1 - 10V, and the working current is 0.1 - 1A; it can be powered on and off 1 - 30 times per minute.

6. The memory alloy pump according to any one of claims 1-5, characterized in that, The amount of liquid medicine flowing into the hose per unit time of the shape memory alloy pump can be estimated by the following method: V = (1 / 3)πR 2 H Where H is the deformation of the shape memory alloy, and R is the radius of the round hole in the middle of the partition.

7. The manufacturing method of the shape memory alloy pump according to claim 6, characterized in that, It includes the following steps: S1: Manufacture the upper shell, and print the upper shell through 3D printing technology; S2: Manufacture the lower shell, and print the lower shell through 3D printing technology; S3: Fabricate a polymer membrane, which is made of polytetrafluoroethylene, polydimethylsiloxane, polyacrylate, silica gel, rubber, latex or polyurethane material; S4: Paste the polymer membrane above the middle circular hole of the partition board, and the polymer membrane is arranged not to cover the surrounding circular small holes; S5: Through holes are respectively arranged at the middle positions of the polymer membrane, the upper wall of the upper shell and the bottom wall of the lower shell; The shape memory alloy wire passes through the polymer membrane and the bottom wall of the lower shell from top to bottom in sequence; The through holes of the polymer membrane and the bottom wall of the lower shell are tightly adapted to the shape memory alloy wire; A knot is tied at the connection of the shape memory alloy wire and the polymer membrane; A knot is tied at the connection of the shape memory alloy wire and the bottom wall of the lower shell; Both ends of the shape memory alloy wire are connected to wires, and the wire connected to the shape memory alloy wire near the polymer membrane end passes through the through hole of the upper wall of the upper shell, and the through hole of the upper wall of the upper shell is tightly adapted to the wire; S6: Assemble the shape memory alloy pump, and the connection between the upper shell and the lower shell, the connection between the shape memory alloy wire and the polymer membrane and the lower shell, and the connection between the wire and the upper shell are sealed with sealant; Both ends of the wire are connected to a power source.

8. An insulin pump system, characterized in that, It includes a liquid storage structure for storing insulin, the shape memory alloy pump according to claim 6 for receiving the liquid storage structure and driving insulin to output downward, and an infusion structure for receiving the insulin output by the shape memory alloy pump and injecting it into the human body, which are connected in sequence from top to bottom; It also includes a microprocessing unit connected to the shape memory alloy pump; The microprocessing unit includes a calculation sub-unit for automatically inputting human blood glucose data, calculating the energization time of the shape memory alloy pump according to the blood glucose data and sending the energization time in sequence, and a control sub-unit for receiving the energization time sent by the calculation sub-unit and controlling the energization and de-energization of the shape memory alloy pump according to the energization time; The shape memory alloy pump is connected to the control sub-unit; The liquid storage structure is internally provided with an alarm module for alarming when the liquid level is lower than a certain position.

9. The insulin pump system according to claim 8, wherein The insulin pump system further includes a blood glucose detection unit connected to the calculation sub-unit of the microprocessing unit, and the blood glucose detection unit is used for detecting human blood glucose data; The blood glucose detection unit is internally provided with a conventional insulin measuring instrument.

10. The insulin pump system according to claim 8, characterized in that, The liquid storage structure is connected to the liquid inlet of the shape memory alloy pump; The concentration of insulin in the liquid storage structure is 1 - 500 U / ml.

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