Sample analysis system

Abstract

The invention discloses a sample analysis system, which comprises a reagent supply assembly, a liquid suction assembly, a cover closing assembly and a controller, and is characterized in that the reagent supply assembly is used for dispatching a reagent container to a liquid suction position and a cover closing position; the liquid suction assembly is used for sucking the reagent in the reagent container when the reagent supply assembly dispatches the target reagent container to the liquid suction level; the cover closing assembly comprises a translation driving mechanism and a cover closing structure, and the translation driving mechanism is used for driving the cover closing structure to horizontally move towards the back of the container cover; the controller is used for controlling the reagent supply assembly to dispatch a target reagent container to a cover closing position and controlling the translation driving mechanism to drive the cover closing structure to horizontally move; wherein in the translation process, the cover closing structure can act on the back of the container cover, in the cover opening state, of the target reagent container. The controller further controls the translation driving mechanism to drive the cover closing structure to horizontally act on the container cover, and the container cover is rapidly rotated from the cover opening state to the cover closing state.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a sample analysis system. Background Art

[0002] During the process of sample testing and analysis by a sample analyzer, it is necessary to aspirate a processing reagent from a reagent container 100 and inject it into a sample to be tested. The processing reagent processes the sample to facilitate testing and analysis.

[0003] After opening the lid of the reagent container 100 and aspirating the reagent, the sample analyzer closes the lid of the reagent container 100 based on its lid-closure structure. The lid is connected to the bottle body of the reagent container 100 through a hinge. The currently adopted lid-closure scheme is that the pressing part of the lid-closure structure acts on the lid of the reagent container 100, applying pressure to the lid to close it.

[0004] However, in this way, the pressing part of the lid-closure structure needs to act on the lid throughout the entire process of lid closure. The acting stroke corresponds to the angle of lid closure, and the acting stroke and time are relatively long, resulting in low efficiency of closing the lid. Summary of the Invention

[0005] To solve at least one of the problems existing in the above-mentioned prior art, according to one aspect of the present invention, a sample analysis system is provided to improve the efficiency of lid closure.

[0006] An embodiment of the present application provides a sample analysis system, including:

[0007] A reagent supply assembly for scheduling a reagent container to an aspiration level and a lid-closure level;

[0008] An aspiration assembly disposed at the aspiration level, the aspiration assembly being configured to aspirate a reagent from the reagent container when the reagent supply assembly schedules the target reagent container to the aspiration level;

[0009] A lid-closure assembly disposed at the lid-closure level, the lid-closure assembly including a translation drive mechanism and a lid-closure structure, the translation drive mechanism being configured to drive the lid-closure structure to move horizontally towards the back of the container lid;

[0010] A controller for controlling the reagent supply assembly to schedule the target reagent container to the lid-closure level, and for controlling the translation drive mechanism to drive the lid-closure structure to move horizontally in a first preset direction by a first set distance; wherein, during the translation process, the lid-closure structure can act on the back of the container lid of the target reagent container in an open-lid state, so that the container lid rotates to a closed-lid state under the action of a horizontal thrust.

[0011] According to some embodiments of the present invention, a convex portion is provided at the hinge position of the container lid;

[0012] The reagent supply component is also used to schedule the reagent container to the open - cap position;

[0013] The sample analysis system further includes an open - cap component disposed at the open - cap position. The open - cap component includes a vertical driving mechanism and an open - cap structure. The vertical driving mechanism is used to drive the open - cap structure to move vertically towards the convex portion;

[0014] The controller is also used to control the reagent supply component to schedule the target reagent container to the open - cap position, and control the vertical driving mechanism to drive the open - cap structure to move downward along a second preset direction by a second set distance; wherein, during the downward movement of the open - cap structure, it can act on the convex portion of the container cap in the closed - cap state of the target reagent container, so that the container cap rotates to the open - cap state under the action of the downward thrust.

[0015] According to some embodiments of the present invention, the reagent supply component includes a reagent tray. A plurality of placement positions for carrying reagent containers are provided on the reagent tray. The reagent tray rotates under the drive of a power mechanism to drive the target reagent container to be scheduled to the open - cap position, the liquid - suction position, and the closed - cap position in sequence.

[0016] According to some embodiments of the present invention, the reagent supply component includes a reagent warehouse and a handling mechanism. A plurality of placement positions for carrying reagent containers are provided in the reagent warehouse. The handling mechanism is used to grab the target reagent container from the reagent warehouse to the open - cap position, the liquid - suction position, and the closed - cap position.

[0017] According to some embodiments of the present invention, the open - cap position, the liquid - suction position, and the closed - cap position are different positions, or the open - cap position, the liquid - suction position, and the closed - cap position are the same position; or the open - cap position and the liquid - suction position are the same position and the closed - cap position is a different position; or the liquid - suction position and the closed - cap position are the same position and the open - cap position is a different position.

[0018] According to some embodiments of the present invention, if the open - cap position, the liquid - suction position, and the closed - cap position are the same position, the sample analysis system further includes an acting member having an open - cap structure and a closed - cap structure. The translation driving mechanism is used to drive the acting member to move horizontally towards the container cap of the container, so that the closed - cap structure of the acting member acts on the back of the lid body portion 120 of the container cap; and the vertical driving mechanism is used to drive the acting member to move vertically towards the convex portion of the container cap, so that the open - cap structure of the acting member acts on the convex portion of the container cap.

[0019] According to some embodiments of the present invention, the container cap is hinged to the reagent container to be able to rotate to open or close the bottle mouth of the reagent container;

[0020] The mouth part of the target reagent container is connected to the container cover by an elastic reset member, and the elastic reset member is configured such that when the target reagent container is in an open state, at least a part of the elastic reset member is located in the dorsal region of the hinge point of the container cover and the target reagent container away from the mouth; when the target reagent container is in a closed state, at least a part of the elastic reset member is located in the front region of the hinge point of the container cover towards the mouth.

[0021] According to some embodiments of the present invention, the elastic reset member is an elastically extensible reset member, one end of the elastic reset member is connected to the container cover to determine a first connection point, and the other end is connected to the mouth part of the target reagent container to determine a second connection point;

[0022] When the included angle between the first connection line of the first connection point and the hinge point and the second connection line between the hinge point and the center point of the plane where the mouth part is located is greater than the included angle between the first connection line and the second connection line in the critical state, the elastic reset member is used to assist in pulling the container cover open;

[0023] Wherein, the critical state is the state corresponding to the first connection point, the hinge point and the second connection point being on the same straight line;

[0024] When the included angle between the first connection line and the second connection line is less than the included angle between the first connection line and the second connection line in the critical state, the elastic reset member is used to assist in pulling the container cover closed.

[0025] According to some embodiments of the present invention, the thickness of the elastic reset member is set to a preset thickness, and / or the width of the elastic reset member is set to a preset width, so that the contraction torque of the elastic reset member reaches a preset contraction torque.

[0026] According to some embodiments of the present invention, the translation driving mechanism has a linear driving part for driving the closed cover structure to move linearly towards the back of the container cover;

[0027] Alternatively, the target reagent sample analysis system further includes a transmission structure, the closed cover structure is slidably arranged, and the transmission structure is connected to the driving part of the translation driving mechanism and the closed cover structure, and is used to switch the rotational driving force of the driving part of the translation driving mechanism into a linear driving force for the closed cover structure, so that the closed cover structure moves linearly towards the back of the container cover under the action of the linear driving force.

[0028] According to some embodiments of the present invention, the controller is further configured to control the translation driving mechanism to drive the lid closing structure to move horizontally at a preset driving power, so that the lid closing structure reaches a preset moving speed of horizontal movement under the drive of the preset driving power.

[0029] According to some embodiments of the present invention, when the target reagent container is in a lid-closed state, the container lid has an included angle with the plane where the mouth of the target reagent container is located, and the range of the included angle is 0 to 8°.

[0030] Embodiments of the present application provide a sample analysis system, including,

[0031] a reagent supply assembly for scheduling a reagent container to a sampling position and a lid closing position;

[0032] a reagent aspiration assembly disposed at the sampling position for aspirating a reagent from the reagent container scheduled to the sampling position;

[0033] a lid closing assembly fixedly disposed between the sampling position and the lid closing position;

[0034] a controller for controlling the reagent supply assembly to schedule a target reagent container to the sampling position, and controlling the reagent aspiration assembly to aspirate the reagent from the target reagent container at the sampling position;

[0035] The controller is further configured to control the reagent supply assembly to schedule the target reagent container from the sampling position to the lid closing position. During the process of scheduling the target reagent container to the lid closing position, the back of the container lid of the target reagent container in an open-lid state moves horizontally towards the lid closing assembly, so that the lid closing assembly generates a horizontal thrust on the back of the container lid of the target reagent container, and the container lid rotates to close under the action of the horizontal thrust.

[0036] According to some embodiments of the present invention, a protrusion is further provided at the tail of the container lid;

[0037] The reagent supply assembly is further configured to schedule the reagent container to an open-lid position;

[0038] The sample analysis system further includes an open-lid structure disposed at the open-lid position;

[0039] The controller is further configured to control the reagent supply assembly to schedule the target reagent container to the open-lid position. During the process of scheduling the target reagent container to the open-lid position, the back of the protrusion of the container lid in a closed-lid state moves vertically towards the open-lid structure. During the vertical movement, the open-lid structure abuts against the container lid and then continues to press down the container lid, so that the container lid rotates to open under the action of the vertical pressure.

[0040] According to some embodiments of the present invention, the reagent supply component is a reagent tray, and a plurality of placement positions for carrying reagent containers are arranged on the reagent tray. The reagent tray rotates under the drive of a power mechanism and drives the target reagent container to be scheduled to the open cap position, the liquid suction position, and the closed cap position in sequence.

[0041] According to some embodiments of the present invention, the reagent supply component includes a reagent warehouse and a handling mechanism. A plurality of placement positions for carrying reagent containers are arranged on the reagent warehouse, and the handling mechanism is used to grab the target reagent container to the open cap position, the liquid suction position, and the closed cap position.

[0042] It can be seen from the above technical solutions that the embodiments of the present application have the following advantages: The controller controls the reagent supply component to carry the target reagent container to the liquid suction position. The container cap is in an open state, and the suction head of the liquid suction component extends into the target reagent container to suck the reagent in the target reagent container. After the liquid suction component completes sampling, the controller controls the reagent supply component to schedule the target reagent container to the closed cap position, and the closing structure is just arranged facing the back of the container cap. At the same time, when the target reagent container is scheduled to the closed cap position, the controller also controls the translation drive mechanism to drive the closing structure to horizontally move a first set distance in the horizontal direction towards the back of the container cap. During the horizontal movement of the closing structure, the closing structure acts on the back of the container cap and pushes the container cap to rotate inwards by a preset angle. After the container cap rotates by the preset angle, under the action of gravity or other forces, the container cap quickly rotates to the closed cap state. Of course, the liquid suction position and the closed cap position can be the same position. When the reagent supply component carries the target reagent container to the liquid suction position, it also carries it to the closed cap position. Description of the Drawings

[0043] Figure 1 It is a schematic structural diagram of the open cap component and the closed cap component in the embodiment of the present invention;

[0044] Figure 2 It is a schematic diagram of the open cap process and state in which the cap of the target reagent container in the embodiment of the present invention is opened;

[0045] Figure 3 It is a schematic diagram of the closed cap process and state in which the cap of the target reagent container in the embodiment of the present invention is closed;

[0046] Figure 4 It is a schematic diagram of the critical state of the cap body in the embodiment of the present invention.

[0047] Reagent container 100, container cap 110, cap body part 120, convex part 130, elastic reset part 140, reagent supply component 200, vertical drive mechanism 300, translation drive mechanism 400, acting part 500, closing structure 510, open cap structure 520. Detailed implementation manners

[0048] For better understanding and implementation, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0049] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation to the present invention.

[0050] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present invention belongs. The terms used in the description of the present invention herein are only for the purpose of describing specific embodiments and are not intended to limit the present invention.

[0051] The present invention will be further described in detail below in conjunction with the accompanying drawings.

[0052] Please refer to Figures 1 to 4 , a container lid 110 closing device provided by an embodiment of the present invention, including a reagent supply component 200, a liquid suction component, a lid closing component and a controller arranged on an equipment machine platform. Among them, the reagent supply component 200 is used to dispatch a reagent container 100 to the liquid suction position and the lid closing position of the equipment machine platform. The liquid suction component is used to suck the reagent in the reagent container 100 when the reagent supply component 200 dispatches the target reagent container 100 to the liquid suction position. The lid closing component includes a translation driving mechanism 400 and a lid closing structure 510. The translation driving mechanism 400 is used to drive the lid closing structure 510 to move horizontally towards the back of the container lid 110. The controller is used to control the reagent supply component 200 to dispatch the target reagent container 100 to the lid closing position, and to control the translation driving mechanism 400 to drive the lid closing structure 510 to move horizontally in a first preset direction by a first set distance; wherein, during the translation process of the lid closing structure 510, it can act on the back of the container lid 110 of the target reagent container 100 in an open lid state, so that the container lid 110 rotates to a closed lid state under the action of a horizontal thrust.

[0053] Among them, the liquid suction position and the lid closing position may be the same position or different positions, which are not limited in this application.

[0054] Specific working process: The controller controls the reagent supply component 200 to transport the target reagent container 100 to the liquid suction position. The container lid 110 is in an open state. The pipette tip of the liquid suction component extends into the target reagent container 100 to aspirate the reagent in the target reagent container 100. After the liquid suction component completes sampling, the controller controls the reagent supply component 200 to dispatch the target reagent container 100 to the lid-closure position, and the lid-closure structure 510 is just arranged facing the back of the container lid 110. Meanwhile, when the target reagent container 100 is dispatched to the lid-closure position, the controller also controls the translation drive mechanism 400 to drive the lid-closure structure 510 to horizontally move a first set distance in the direction of the back of the container lid 110. During the horizontal movement of the lid-closure structure 510, the lid-closure structure 510 acts on the back of the container lid 110 and pushes the container lid 110 to rotate inward by a preset angle. After the container lid 110 rotates by the preset angle, under the action of gravity or other forces, the container lid 110 quickly rotates to the closed-lid state. Of course, the liquid suction position and the lid-closure position can be the same position. When the reagent supply component 200 transports the target reagent container 100 to the liquid suction position, it also transports it to the lid-closure position.

[0055] As can be seen from the above, compared with the prior art, the lid-closure structure 510 needs a relatively complex movement stroke to complete the rotation of the container lid 110 to the closed-lid state. In this application, when the target reagent container 100 moves to the lid-closure position, the translation drive mechanism 400 only needs to drive the lid-closure structure 510 to horizontally move a first set distance, and the container lid 110 can rotate from the open-lid state to the closed-lid state. Thus, the lid-closure component can quickly complete the lid closure of the container lid 110, improve the closing efficiency of the container lid 110, and thereby improve the overall working efficiency of the sample analysis system.

[0056] In order to enable the container lid 110 to be automatically opened, in some embodiments, a convex portion 130 is provided at the hinge position of the container lid 110. More precisely, the container lid 110 includes a lid body portion 120 and a convex portion 130. The lid body portion 120 is hinged to the bottle mouth portion of the reagent container 100 and is used to close or open the bottle mouth of the reagent container 100. The edge portion of the lid body portion 120 near its hinge position is connected to the convex portion 130. The sample analysis system further includes an open-lid component provided on the equipment machine table. The open-lid component can act downward on the convex portion 130 of the container lid 110 to enable the container lid 110 to be automatically opened.

[0057] Specifically, the reagent supply component 200 is further configured to schedule the target reagent container 100 to the open cap position. The sample analysis system further includes an open cap structure 520 located at the open cap position. The open cap structure 520 includes a vertical driving mechanism 300 and an open cap structure 520. The vertical driving mechanism 300 is configured to drive the open cap structure 520 to move vertically towards the protruding portion 130. The controller is further configured to control the reagent supply component 200 to schedule the target reagent container 100 to the open cap position, and to control the vertical driving mechanism 300 to drive the open cap structure 520 to move downward a second set distance along a second preset direction. Wherein, during the downward movement of the open cap structure 520, it can act on the protruding portion 130 of the container cap 110 of the target reagent container 100 in a closed cap state, so that the container cap 110 rotates to an open cap state under the action of the downward thrust.

[0058] During the specific working process, before the controller controls the reagent supply component 200 to transport the target reagent container 100 to the liquid suction position, the controller controls the reagent supply component 200 to transport the target reagent container 100 to the open cap position, and the open cap structure 520 is just vertically arranged towards the protruding portion 130 of the container cap 110. At the same time, when the target reagent container 100 is scheduled to the open cap position, the controller also controls the vertical driving mechanism 300 to drive the open cap structure 520 to move downward a second set distance vertically towards the back direction of the container cap 110. During the vertical downward movement of the open cap structure 520, the open cap structure 520 acts on the protruding portion 130 of the container cap 110 and pushes the container cap 110 to rotate outwards by a preset angle. After the container cap 110 rotates by the preset angle, it quickly rotates to the open cap state. Of course, the open cap position and the liquid suction position can be the same position. When the reagent supply component 200 transports the target reagent container 100 to the open cap position, it also transports it to the liquid suction position.

[0059] In order to implement the scheduling of the target reagent container 100, in a possible embodiment, the reagent supply component 200 includes a reagent tray and a power mechanism. Among them, the power structure can be a conveying device annularly arranged on the equipment table, or a conveying device linearly arranged on the equipment table. The reagent tray is a carrier fixedly arranged on the conveying part of the conveying device. A plurality of placement positions are evenly arranged on the reagent tray. The placement positions can be accommodation grooves or other positioning structures arranged on the reagent tray, and each placement position is used to place the reagent container 100. The power mechanism drives the reagent plate to rotate or move linearly along a preset track, and the reagent tray sequentially schedules the target reagent container 100 to the open cap position, the liquid suction position and the closed cap position.

[0060] Specifically, a manipulator or a human worker places each target reagent container 100 at each placement position on the reagent tray. The power mechanism schedules the target reagent container 100 to the open - cap position through the reagent tray. The open - cap assembly acts downward on the protruding portion 130 of the container cap 110 through the open - cap structure 520. Under the action of the open - cap structure 520, the container cap 110 rotates from the closed - cap state to the open - cap state. Then, the power mechanism schedules the target reagent container 100 to the liquid - suction position through the reagent tray. The suction head of the liquid - suction assembly extends into the target reagent container 100 to suck the reagent in the target reagent container 100. Finally, the power mechanism schedules the target reagent container 100 to the closed - cap position through the reagent tray. The closed - cap assembly acts horizontally on the cap body portion 120 of the container cap 110 through the closed - cap structure 510. Under the action of the closed - cap structure 510, the cap body portion 120 of the container cap 110 rotates from the open - cap state to the closed - cap state.

[0061] In some embodiments, the reagent supply assembly 200 includes a reagent storage and a handling mechanism. Among them, a plurality of placement positions are evenly arranged on the reagent storage. The placement positions can be accommodation grooves or other positioning structures arranged on the reagent storage. Each placement position of the reagent storage is used to store the reagent container 100. The reagent storage can be a carrier on a conveying device, and the handling mechanism can be a manipulator. One or more manipulators can be provided, which are used to grab the target reagent container 100 from the reagent storage to the open - cap position, the liquid - suction position, and the closed - cap position.

[0062] During the specific working process, the handling mechanism schedules the target reagent container 100 from the reagent storage to the open - cap position. The open - cap assembly acts downward on the protruding portion 130 of the container cap 110 through the open - cap structure 520. Under the action of the open - cap structure 520, the container cap 110 rotates from the closed - cap state to the open - cap state. Then, the handling mechanism schedules the target reagent container 100 to the liquid - suction position. The suction head of the liquid - suction assembly extends into the target reagent container 100 to suck the reagent in the target reagent container 100. Finally, the handling mechanism schedules the target reagent container 100 to the closed - cap position. The closed - cap assembly acts horizontally on the cap body portion 120 of the container cap 110 through the closed - cap structure 510. Under the action of the closed - cap structure 510, the cap body portion 120 of the container cap 110 rotates from the open - cap state to the closed - cap state.

[0063] In some embodiments, the open lid position, the liquid suction position, and the closed lid position are different positions, and the open lid operation, the liquid suction operation, and the closed lid operation of the reagent container 100 are completed at the same position. With such a setting, the functional modules of the sample analysis system are relatively concentrated, and the overall occupied space of the sample analysis system is small. Alternatively, the open lid position, the liquid suction position, and the closed lid position are the same position, and the open lid operation, the liquid suction operation, and the closed lid operation of the reagent container 100 are completed at different positions. With such a setting, the open lid operation, the liquid suction operation, and the closed lid operation can work continuously to ensure the working efficiency of the sample analysis system. Alternatively, the open lid position and the liquid suction position are the same position, and the closed lid position is a different position. The open lid operation and the liquid suction operation of the reagent container 100 are completed at the same position, and the closed lid operation of the reagent container 100 is completed at a different position from the above position. Or, the liquid suction position is the same position and the open lid position is a different position. With such a setting, after the open lid operation of the reagent container 100 is completed at one position, the reagent container 100 is transferred to the next position, and the liquid suction operation and the closed lid operation of the reagent container 100 are completed at this position.

[0064] In a possible embodiment, if the open lid position, the liquid suction position, and the closed lid position are the same position, the open lid assembly and the closed lid assembly can be integrated together to realize the opening or closing of the container lid 110. If the open lid assembly and the closed lid assembly are integrated together, the sample analysis system further includes an acting member 500 having an open lid structure 520 and a closed lid structure 510. The main body of the translation driving mechanism 400 is connected to the driving part of the vertical driving mechanism 300, and the acting member 500 is connected to the driving part of the translation driving mechanism 400. Here, the translation driving mechanism 400 and the vertical driving mechanism 300 can also be swapped positions, and the acting member 500 is connected to the driving part of the vertical driving mechanism 300. Thus, the translation driving mechanism 400 is used to drive the acting member 500 to move horizontally towards the container lid 110 of the container lid 110, so that the closed lid structure 510 of the acting member 500 acts on the back of the lid body part 120 of the container lid 110; at the same time, the vertical driving mechanism 300 is used to drive the acting member 500 to move vertically towards the protruding part 130 of the container lid 110, so that the open lid structure 520 of the acting member 500 acts on the protruding part 130 of the container lid 110.

[0065] Specifically, during the opening stage of the container lid 110, the vertical driving mechanism 300 drives the acting member 500 to move vertically towards the protruding part 130 of the container lid 110, and the open lid structure 520 of the acting member 500 acts on the protruding part 130 of the container lid 110. Under the action of the acting member 500, the container lid 110 rotates from the closed lid state to the open lid state; during the closed state of the container lid 110, the translation driving mechanism 400 drives the acting member 500 to move horizontally towards the lid body part 120 of the container lid 110, and the closed lid structure 510 of the acting member 500 acts on the back of the lid body part 120 of the container lid 110. Under the action of the acting member 500, the container lid 110 rotates from the open lid state to the closed lid state.

[0066] In other embodiments, the open - lid assembly and the closed - lid assembly may not be integrated together and are two independent mechanisms. More precisely, the translation drive mechanism 400 and the vertical drive mechanism 300 are separately arranged, and the open - lid structure 520 and the closed - lid structure 510 are also two acting members 500 arranged separately, which will not be elaborated here.

[0067] In some embodiments, the container lid 110 is hinged to the target reagent container 100 to be able to rotate to open or close the mouth of the target reagent container 100. The mouth part of the target reagent container 100 and the container lid 110 are connected by an elastic reset member 140. The elastic reset member 140 is configured such that when the target reagent container 100 is in the open - lid state, the elastic reset member 140 is at least partially located in the dorsal region of the hinge point between the container lid 110 and the target reagent container 100 that is away from the mouth; when the target reagent container 100 is in the closed - lid state, the elastic reset member 140 is at least partially located in the positive - side region of the hinge point of the container lid 110 that faces the mouth.

[0068] As Figure 2 shown, when the target reagent container 100 is in the open - lid state, the elastic reset member 140 is at least partially located in the dorsal region away from the mouth of the hinge point (i.e., point B in the figure) between the container lid 110 and the target reagent container 100, that is, the region corresponding to points A and C in the figure. Thus, the elastic reset member 140 can provide a tensile force towards this dorsal region for the opening of the container lid 110.

[0069] As Figure 3 shown, when the target reagent container 100 is in the closed - lid state, including the state of being already closed and about to be closed, at this time the elastic reset member 140 is at least partially located in the positive - side region of the hinge point (i.e., point B in the figure) of the container lid 110 that faces the mouth, that is, the region corresponding to points A and C in the figure. Thus, the elastic reset member 140 can provide a tensile force towards this positive - side region for the closing of the container lid 110.

[0070] In some embodiments, the elastic reset member 140 is an elastically extensible reset member. One end of the elastic reset member 140 is connected to the container lid 110 to determine a first connection point, and the other end is connected to the mouth part of the target reagent container 100 to determine a second connection point.

[0071] In some embodiments, in the critical state, the deformation amount of the elastic reset member 140 is the largest. The critical state is the state corresponding to when the first connection point, the hinge point, and the second connection point are on the same straight line. As Figure 4As shown, when the first connection point (i.e., point C in the figure) is on the same straight line as the hinge point (i.e., point B in the figure) and the second connection point (i.e., point A in the figure), the deformation of the elastic reset member 140 is the largest at this time. When the first connection line between the first connection point and the hinge point, and the second connection line between the hinge point and the center point of the bottle mouth part (such as the dotted line where point B is located as shown in Figure 4 ), the included angle between the two connection lines is greater than the included angle between the first connection line and the second connection line in the critical state. At this time, the direction of the force is not perpendicular to the direction of motion, and the component force in the direction of motion will assist in opening the lid. Then the elastic reset member 140 is used to assist in pulling the container lid 110 to open; when the included angle between the first connection line and the second connection line is less than the included angle between the first connection line and the second connection line in the critical state, at this time, the direction of the force is not perpendicular to the direction of motion, and the component force in the direction of motion will assist in closing the lid. Then the elastic reset member 140 is used to assist in pulling the container lid 110 to close.

[0072] In one embodiment, to make the sealing effect of the container lid 110 on the target reagent container 100 better, the thickness of the elastic reset member 140 reaches a preset thickness, and / or the width of the elastic reset member 140 reaches a preset width, so that the contraction torque of the elastic reset member 140 reaches a preset contraction torque. For example, increasing the contraction torque of the elastic reset member 140 to increase the tensile force exerted by the elastic reset member 140 on the container lid 110, so that the elastic reset member 140 fits more closely to the bottle mouth under the action of a greater tensile force, thereby making the sealing effect better.

[0073] In some embodiments, to make the sealing effect of the container lid 110 on the target reagent container 100 better, the controller can also control the horizontal drive mechanism to drive the lid closing structure 510 to move horizontally at a preset drive power, so that the lid closing structure 510 reaches a preset moving speed of horizontal movement under the drive of the preset drive power. For example, increasing the speed of the lid closing structure 510 moving horizontally towards the back of the container lid 110, thereby increasing the thrust exerted by the lid closing structure 510 on the container lid 110, so that the container lid 110 can rotate and fit to the bottle mouth at a greater initial speed, thereby achieving a better sealing effect.

[0074] In this embodiment, when the target reagent container 100 is in the closed lid state, the container lid 110 has an included angle with the plane where the bottle mouth part of the target reagent container 100 is located. This included angle can seal the bottle mouth within a preset range to prevent air from entering the container interior, and can isolate the interior of the container from the exterior of the container. The smaller this included angle is, the better the sealing effect. In a preferred implementation, the range of this included angle is a preset range such as 0 to 8° that can achieve bottle mouth sealing.

[0075] Of course, in addition to the above methods, other methods can also be used to achieve a better sealing effect. For example, magnetic members can be respectively arranged at the positions where the bottle mouth and the container lid 110 are in contact to achieve magnetic attraction sealing, and so on. This embodiment does not limit the methods for achieving a better sealing effect.

[0076] To achieve the linear motion of the acting member 500, in some embodiments, the translation driving mechanism 400 has a linear driving part for driving the lid closing structure 510 to move linearly towards the back of the container lid 110. For example, the translation driving mechanism 400 can adopt structures such as a linear motor, a cylinder, or an electric push rod.

[0077] In other possible embodiments, the target reagent sample analysis system further includes a transmission structure. The lid closing structure 510 is slidably arranged on the mounting frame of the equipment machine table. The transmission structure is connected to the driving part of the translation driving mechanism 400 and the lid closing structure 510, and is used to switch the rotational driving force of the driving part of the translation driving mechanism 400 into a linear driving force for the lid closing structure 510, so that the lid closing structure 510 moves linearly towards the back of the container lid 110 under the action of the linear driving force. Among them, the transmission structure can be a gear-rack structure, a crank-link structure, or a lead screw-slider structure, etc., all of which can realize the conversion of rotational driving to linear driving.

[0078] This application also discloses a sample analysis system, including a reagent supply component 200, a reagent aspiration component, a lid closing component, and a controller arranged on the equipment machine table. Among them, the reagent supply component 200 is used to schedule the reagent container 100 to the sample aspiration position and the lid closing position; the reagent aspiration component is arranged at the sample aspiration position and is used to aspirate the reagent in the reagent container 100 scheduled to the sample aspiration position; the lid closing component is fixedly arranged between the sample aspiration position and the lid closing position; the controller is used to control the reagent supply component 200 to schedule the target reagent container 100 to the sample aspiration position, and control the reagent aspiration component to aspirate the reagent in the target reagent container 100 at the sample aspiration position; the controller is also used to control the reagent supply component 200 to schedule the target reagent container 100 from the sample aspiration position to the lid closing position. During the process of scheduling the target reagent container 100 to the lid closing position, the back of the container lid 110 of the target reagent container 100 in the open lid state moves horizontally towards the lid closing component, so that the lid closing component generates a horizontal thrust on the back of the container lid 110 of the target reagent container 100, and the container lid 110 rotates to close the lid under the action of the horizontal thrust.

[0079] In the specific working process, the controller controls the reagent supply component 200 to move the target reagent container 100 to the liquid suction position. The container cover 110 is in an open state. The pipette tip of the liquid suction component extends into the target reagent container 100 to aspirate the reagent in the target reagent container 100. After the liquid suction component completes sampling, the controller controls the reagent supply component 200 to transfer the target reagent container 100 from the liquid suction position to the lid-closure position. The lid-closure component is just on the movement path of the container cover 110 and faces the back of the container cover 110. Therefore, between the reagent supply component 200 driving the target reagent container 100 from the liquid suction position to the lid-closure position, the container cover 110 just passes through the position of the lid-closure component. Thus, the lid-closure component just acts on the back of the container cover 110, thereby pushing the container cover 110 to close automatically. It can be understood that the lid-closure component does not need to be provided with a separate power source to drive its movement, saving costs.

[0080] In order to enable the container cover 110 to open automatically, in some embodiments, a protrusion 130 is provided at the hinge position of the container cover 110. More precisely, the container cover 110 includes a cover body portion 120 and a protrusion 130. The cover body portion 120 is hingedly connected to the bottle mouth portion of the reagent container 100 for closing or opening the bottle mouth of the reagent container 100. The edge portion of the cover body portion 120 near its hinge position is connected to the protrusion 130. The sample analysis system further includes an open-lid component provided on the equipment table. The open-lid component can act downward on the protrusion 130 of the container cover 110 to enable the container cover 110 to open automatically.

[0081] In a specific embodiment, the reagent supply component 200 of the lid-closure component is further used to transfer the reagent container 100 to the open-lid position; the sample analysis system of the lid-closure component further includes an open-lid structure 520 which is arranged at the open-lid position of the lid-closure component; the controller of the lid-closure component is further used to control the reagent supply component 200 of the lid-closure component to transfer the target reagent container 100 of the lid-closure component to the open-lid position of the lid-closure component. During the process of transferring the target reagent container 100 of the lid-closure component to the open-lid position of the lid-closure component, the back of the protrusion 130 of the container cover 110 in the closed state of the lid-closure component faces the open-lid structure 520 of the lid-closure component and moves vertically. During the vertical movement, the open-lid structure 520 of the lid-closure component abuts against the container cover 110 of the lid-closure component and continues to press down the container cover 110 of the lid-closure component, so that the container cover 110 of the lid-closure component rotates to open under the action of the vertical pressure.

[0082] In the specific working process, the controller controls the reagent supply component 200 to move the target reagent container 100 to the open - cap position. During the movement of the target reagent container 100, the open - cap component is just on the movement path of the container cap 110 and faces the protruding part 130 of the container cap 110, and the above - mentioned close - cap component acts on the cap body part 120 of the container cap 110. Therefore, during the process of the reagent supply component 200 driving the target reagent container 100 to move, when the container cap 110 passes through the position of the open - cap component, the guiding inclined surface on the side of the open - cap component just acts on the protruding part 130 of the container cap 110, thereby pushing the container cap 110 to open automatically. It can be understood that there is no need to set a separate power source to drive the movement of the open - cap component, which saves costs.

[0083] In order to realize the scheduling of the target reagent container 100, in a possible embodiment, the reagent supply component 200 includes a reagent tray arranged on a power mechanism. Among them, the power structure can be a conveying device annularly arranged on the equipment table or a conveying device linearly arranged on the equipment table, and the reagent tray is a carrier fixedly arranged on the conveying part of the conveying device. A plurality of placement positions are evenly arranged on the reagent tray. The placement positions can be accommodation grooves or other positioning structures arranged on the reagent tray, and each placement position is used to place the reagent container 100. The power mechanism drives the reagent tray to rotate or move linearly along a preset track, and the reagent tray sequentially schedules the target reagent container 100 to the open - cap position, the liquid - suction position, and the close - cap position.

[0084] Specifically, a manipulator or manual labor places each target reagent container 100 in each placement position of the reagent tray. The power mechanism schedules the target reagent container 100 to the open - cap position through the reagent tray. The open - cap component acts downward on the protruding part 130 of the container cap 110 through the open - cap structure 520. Under the action of the open - cap structure 520, the container cap 110 rotates from the closed - cap state to the open - cap state; then, the power mechanism schedules the target reagent container 100 to the liquid - suction position through the reagent tray, and the suction head of the liquid - suction component extends into the target reagent container 100 to suck the reagent in the target reagent container 100. Finally, the power mechanism schedules the target reagent container 100 to the close - cap position through the reagent tray, and the close - cap component acts horizontally on the cap body part 120 of the container cap 110 through the close - cap structure 510. Under the action of the close - cap structure 510, the cap body part 120 of the container cap 110 rotates from the open - cap state to the closed - cap state.

[0085] In some embodiments, the reagent supply component 200 includes a reagent storage and a handling mechanism. Among them, a plurality of placement positions are evenly arranged on the reagent storage. The placement positions can be accommodation grooves or other positioning structures arranged on the reagent storage, and each placement position of the reagent storage is used to store the reagent container 100. The reagent storage can be a carrier on the conveying device, and the handling mechanism can be a manipulator. One or more manipulators can be set to grab the target reagent container 100 from the reagent storage to the open - cap position, the liquid - suction position, and the close - cap position.

[0086] During the specific working process, the handling mechanism schedules the target reagent container 100 from the reagent storage to the open - cap position. The open - cap assembly acts downward on the protruding part 130 of the container cap 110 through the open - cap structure 520. Under the action of the open - cap structure 520, the container cap 110 rotates from the closed - cap state to the open - cap state. Then, the handling mechanism schedules the target reagent container 100 to the liquid - suction position, and the suction head of the liquid - suction assembly extends into the target reagent container 100 to suck the reagent in the target reagent container 100. Finally, the handling mechanism schedules the target reagent container 100 to the closed - cap position, and the closed - cap assembly acts horizontally on the cover body part 120 of the container cap 110 through the closed - cap structure 510. Under the action of the closed - cap structure 510, the cover body part 120 of the container cap 110 rotates from the open - cap state to the closed - cap state.

[0087] The technical means disclosed in the solution of the present invention are not limited to the technical means disclosed in the above - mentioned embodiments, but also include technical solutions composed of any combination of the above technical features. It should be noted that for those of ordinary skill in the art of this technology, without departing from the principle of the present invention, several improvements and retouches can be made, and these improvements and retouches are also regarded as the protection scope of the present invention.

Claims

1. A sample analysis system, characterized in that, including, a reagent supply component for scheduling a reagent container to a liquid suction position and a lid closing position; a liquid suction component disposed at the liquid suction position, the liquid suction component being configured to suck the reagent in the reagent container when the reagent supply component schedules the target reagent container to the liquid suction position; a lid closing component disposed at the lid closing position, the lid closing component including a translation driving mechanism and a lid closing structure, the translation driving mechanism being configured to drive the lid closing structure to move horizontally toward the back of the container lid; a controller for controlling the reagent supply component to schedule the target reagent container to the lid closing position, and for controlling the translation driving mechanism to drive the lid closing structure to move horizontally a first set distance in a first preset direction; wherein, during the translation process, the lid closing structure can act on the back of the container lid of the target reagent container in an open lid state, so that the container lid rotates to a closed lid state under the action of the horizontal thrust.

2. The sample analysis system according to claim 1, characterized in that, a protrusion is provided at the hinge position of the container lid; the reagent supply component is further configured to schedule the reagent container to an open lid position; the sample analysis system further includes an open lid component disposed at the open lid position, the open lid component including a vertical driving mechanism and an open lid structure, the vertical driving mechanism being configured to drive the open lid structure to move vertically toward the protrusion; the controller is further configured to control the reagent supply component to schedule the target reagent container to the open lid position, and to control the vertical driving mechanism to drive the open lid structure to move downward a second set distance in a second preset direction; wherein, during the downward movement, the open lid structure can act on the protrusion of the container lid of the target reagent container in a closed lid state, so that the container lid rotates to an open lid state under the action of the downward thrust.

3. The sample analysis system according to claim 2, characterized in that, the reagent supply component includes a reagent tray, and a plurality of placement positions for carrying reagent containers are provided on the reagent tray, and the reagent tray rotates under the drive of a power mechanism to drive the target reagent container to be sequentially scheduled to the open lid position, the liquid suction position, and the lid closing position.

4. The sample analysis system according to claim 2, wherein the reagent supply component includes a reagent warehouse and a handling mechanism, the reagent warehouse is provided with a plurality of placement positions for carrying reagent containers, and the handling mechanism is configured to grab the target reagent container from the reagent warehouse to the open lid position, the liquid suction position, and the lid closing position.

5. A sample analysis system according to any one of claims 1-4, characterized in that, the open lid position, the liquid suction position, and the lid closing position are different positions, or the open lid position, the liquid suction position, and the lid closing position are the same position; or the open lid position and the liquid suction position are the same position and the lid closing position is a different position; or the liquid suction position and the lid closing position are the same position and the open lid position is a different position.

6. The sample analysis system according to claim 2, wherein if the open lid position, the liquid suction position, and the lid closing position are the same position, the sample analysis system further includes an acting member having an open lid structure and a lid closing structure, the translation driving mechanism being configured to drive the acting member to move horizontally toward the container lid, so that the lid closing structure of the acting member acts on the back of the lid body portion of the container lid; and the vertical driving mechanism is configured to drive the acting member to move vertically toward the protrusion of the container lid, so that the open lid structure of the acting member acts on the protrusion of the container lid.

7. The sample analysis system according to any one of claims 1 to 6, characterized in that, The container cover is hinged to the reagent container so as to be able to rotate to open or close the bottle mouth of the reagent container; The bottle mouth part of the target reagent container is connected to the container cover through an elastic reset member, and the elastic reset member is configured such that when the target reagent container is in an open lid state, at least part of the elastic reset member is located in the dorsal area of the hinge point of the container cover and the target reagent container away from the bottle mouth; when the target reagent container is in a closed lid state, at least part of the elastic reset member is located in the positive side area of the hinge point of the container cover towards the bottle mouth.

8. A sample analysis system according to claim 7, characterized in that, The elastic reset member is an elastically telescopic reset member, one end of the elastic reset member is connected to the container cover to determine a first connection point, and the other end is connected to the bottle mouth part of the target reagent container to determine a second connection point; When the included angle between the first connection line between the first connection point and the hinge point and the second connection line between the hinge point and the center point of the plane where the bottle mouth part is located is greater than the included angle between the first connection line and the second connection line in the critical state, the elastic reset member is used to assist in pulling the container cover open; Wherein, the critical state is the state corresponding to the first connection point, the hinge point and the second connection point being on the same straight line; When the included angle between the first connection line and the second connection line is less than the included angle between the first connection line and the second connection line in the critical state, the elastic reset member is used to assist in pulling the container cover closed.

9. The sample analysis system according to claim 7 or 8, characterized in that The thickness of the elastic reset member is set to a preset thickness, and / or the width of the elastic reset member is set to a preset width, so that the contraction torque of the elastic reset member reaches a preset contraction torque.

10. A sample analysis system according to any one of claims 1 to 9, characterized in that, The translation drive mechanism has a linear drive part for driving the lid closing structure to move linearly towards the back of the container cover; Or, the target reagent sample analysis system further includes a transmission structure, the lid closing structure is slidably arranged, and the transmission structure is connected to the drive part of the translation drive mechanism and the lid closing structure, and is used to switch the rotational driving force of the drive part of the translation drive mechanism into a linear driving force for the lid closing structure, so that the lid closing structure moves linearly towards the back of the container cover under the action of the linear driving force.

11. The sample analysis system according to any one of claims 1 to 9, characterized in that, The controller is further used to control the translation drive mechanism to drive the lid closing structure to move horizontally with a preset driving power, so that the lid closing structure reaches a preset moving speed of horizontal movement under the drive of the preset driving power.

12. The sample analysis system according to any one of claims 1 to 9, characterized in that, When the target reagent container is in a closed lid state, the plane where the container cover and the bottle mouth of the target reagent container are located has an included angle, and the range of the included angle is 0 to 8°.

13. A sample analysis system, characterized in that, Including, A reagent supply component for scheduling the reagent container to the sampling position and the lid closing position; A reagent aspiration component arranged at the sampling position for aspirating the reagent in the reagent container scheduled to the sampling position; A lid closing component fixedly arranged between the sampling position and the lid closing position; A controller for controlling the reagent supply component to schedule the target reagent container to the sampling position, and controlling the reagent aspiration component to aspirate the reagent in the target reagent container at the sampling position; The controller is further configured to control the reagent supply component to schedule the target reagent container from the sampling position to the lid-closing position. During the process of scheduling the target reagent container to the lid-closing position, the back of the container lid of the target reagent container in the open-lid state moves horizontally towards the lid-closing component, so that the lid-closing component generates a horizontal thrust on the back of the container lid of the target reagent container, and the container lid rotates to close the lid under the action of the horizontal thrust.

14. A sample analysis system according to claim 13, characterized in that, A convex portion is provided at the hinge position of the container lid; The reagent supply component is further configured to schedule the reagent container to the open-lid position; The sample analysis system further includes an open-lid structure, which is provided at the open-lid position; The controller is further configured to control the reagent supply component to schedule the target reagent container to the open-lid position. During the process of scheduling the target reagent container to the open-lid position, the back of the convex portion of the container lid in the closed-lid state moves vertically towards the open-lid structure. During the vertical movement, the open-lid structure abuts against the container lid and then continues to press down the container lid, so that the container lid rotates to open the lid under the action of the vertical pressure.

15. A sample analysis system according to claim 14, characterized in that, The reagent supply component is a reagent tray, and a plurality of placement positions for carrying reagent containers are provided on the reagent tray. The reagent tray rotates under the drive of a power mechanism and drives the target reagent container to be scheduled to the open-lid position, the liquid-sampling position, and the lid-closing position in sequence.

16. A sample analysis system according to claim 14, wherein, The reagent supply component includes a reagent warehouse and a handling mechanism. A plurality of placement positions for carrying reagent containers are provided on the reagent warehouse. The handling mechanism is configured to grab the target reagent container to the open-lid position, the liquid-sampling position, and the lid-closing position.

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