Novel ophthalmic medicine and preparation method thereof

Abstract

The invention discloses a novel ophthalmic medicine and a preparation method thereof.The novel ophthalmic medicine is prepared from semen cassiae, glossy privet fruit, chrysanthemum, Chinese yam, schisandra chinensis, mint, ginger, fructus lycii, astragalus membranaceus, coptis chinensis, angelica sinensis, codonopsis pilosula, pearl powder, poria cocos, radix curcumae and other traditional Chinese medicinal materials, and the preparation method comprises the steps of mixing the medicinal materials, decocting, filtering, filling and the like, before use, cleaning and disinfection are needed, the decoction time is 1-2 hours, the decoction temperature is 100-120 DEG C, a filter is made of gauze and filter paper, after filtration, standing and re-filtration are needed, and finally, an ultraviolet germicidal lamp and high-temperature disinfection are used for disinfecting a container, so that sanitation and safety of the medicine are ensured. The medicine contains various traditional Chinese medicinal materials, and has a very good health-care effect on myopia, presbyopia, astigmatism, amblyopia, photophobia and tear induced by wind.

Description

Technical Field

[0001] The present invention relates to the technical field of ophthalmic drugs, and more particularly to a novel ophthalmic drug and its preparation method. Background Art

[0002] Eye diseases are common diseases, such as dry eye, conjunctivitis, keratitis, etc. Traditional treatment methods mainly use artificial tears, antibiotic eye drops, etc., but these treatment methods have some disadvantages, such as it is difficult to guarantee the purity and hygienic safety of drugs, and the treatment effect is not good. Therefore, developing a novel ophthalmic drug has important clinical application value.

[0003] As a traditional treatment method, Chinese herbal medicine has the advantages of obvious medicinal effects and small side effects, so it has been widely used in the treatment of eye diseases. However, there are some problems with traditional Chinese herbal medicine decocting methods, such as it is difficult to guarantee the hygiene and safety of medicinal material decoction, and the purity of drugs is not high. Therefore, studying a novel Chinese herbal medicine decocting method has important theoretical and practical significance. Summary of the Invention

[0004] In view of this, the present invention discloses a novel ophthalmic drug and its preparation method. It is prepared by mixing multiple Chinese herbal medicines, and through steps such as decocting, filtering and filling, a pure, hygienic and safe drug is prepared. This preparation method can improve the purity and hygienic safety of drugs and is applicable to the treatment of eye diseases.

[0005] To achieve the above object, the present invention provides the following technical solutions, including the following parts by weight: 30 - 50 parts of cassia seed, 5 - 15 parts of glossy privet fruit, 20 - 40 parts of chrysanthemum, 5 - 15 parts of Chinese yam, 5 - 15 parts of schisandra chinensis, 40 - 60 parts of mint, 10 - 30 parts of ginger, 10 - 30 parts of wolfberry fruit, 5 - 15 parts of astragalus membranaceus, 40 - 60 parts of coptis chinensis, 5 - 15 parts of angelica sinensis, 10 - 20 parts of codonopsis pilosula, 20 - 30 parts of pearl powder, 5 - 15 parts of poria cocos and 5 - 10 parts of curcuma aromatica.

[0006] The preparation method of the above novel ophthalmic drug includes the following steps:

[0007] a: Mix the components in Claim 1 evenly according to the ratio;

[0008] b: Decoct the mixed medicinal materials with water until concentrated to obtain the drug;

[0009] c: Filter the drug to remove impurities to obtain a pure drug;

[0010] d: Fill the drug into a suitable container and seal it for storage.

[0011] Preferably, in the preparation method of the above-mentioned novel ophthalmic drug, the container used for decocting is a stainless-steel pot or a porcelain casserole. Before using the container, it needs to be cleaned and disinfected first to ensure the hygiene and safety of the medicinal material decoction.

[0012] Preferably, in the preparation method of the above-mentioned novel ophthalmic drug, the decocting time is 1 - 2 hours, and the decocting temperature is 100 - 120 °C.

[0013] Preferably, in the preparation method of the above-mentioned novel ophthalmic drug, the filtration step includes pouring the drug into a filter, and the filter is made of gauze and filter paper. Attention should be paid to the tightness of the filter during filtration to avoid drug loss. After filtration, let the drug stand for a while again to make the remaining impurities precipitate to the bottom. Pour the drug into a clean container, use a funnel to avoid splashing of the drug. Finally, disinfect the container with an ultraviolet germicidal lamp and high-temperature disinfection to ensure the hygiene and safety of the drug.

[0014] As can be seen from the above technical solutions, compared with the prior art, the present invention discloses a novel ophthalmic drug and its preparation method. By improving the purity, hygiene and safety of the drug, reducing impurities and pollutants in the drug, and reducing the irritation and toxicity of the drug to the eyes, the therapeutic effect is improved and the incidence of adverse reactions is reduced. Prepared by mixing multiple Chinese herbal medicines, it has the advantages of obvious medicinal effect and small side effects, and can effectively treat eye diseases and improve the quality of life of patients. The preparation method is simple, easy to operate, suitable for large-scale production, and can meet the clinical needs. By cleaning and disinfecting the container, the hygiene and safety of the medicinal material decoction are guaranteed, and the quality and safety of the drug are ensured from the source.

[0015] In summary, this novel ophthalmic drug and its preparation method have important clinical application value and economic value. Specific Embodiments

[0016] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0017] Example 1:

[0018] Prepare 30 parts of cassia seeds, 5 parts of glossy privet fruits, 20 parts of chrysanthemums, 5 parts of Chinese yams, 5 parts of magnoliavine fruits, 40 parts of mints, 10 parts of ginger, 10 parts of wolfberries, 5 parts of astragalus membranaceus, 40 parts of coptis chinensis, 5 parts of angelica sinensis, 10 parts of codonopsis pilosula, 20 parts of pearl powder, 5 parts of poria cocos and 5 parts of turmeric, which are the raw materials for making the medicine.

[0019] Mix the herbal medicines evenly, add an appropriate amount of water, put them into a pot and decoct. Control the decocting temperature at about 100°C and the decocting time for 1 hour. Pour the decocted medicinal powder into a filter for filtration, then fill the medicinal powder into a suitable container and seal it for storage. When using, first remove the upper layer of gauze, then apply the well-stirred medicinal powder onto the gauze, cover it with another layer of gauze, and remove it after 30 to 60 minutes. Use it once a day, which has very good health care effects on myopia, hyperopia, astigmatism, presbyopia, epiphora in the wind, poor vision in dim light, cataract, glaucoma, floaters, macular disease, and eye inflammation.

[0020] Example Two:

[0021] Prepare the raw materials for making the medicine: 50 parts of cassia seeds, 15 parts of glossy privet fruits, 40 parts of chrysanthemums, 15 parts of Chinese yams, 15 parts of schisandra berries, 60 parts of mints, 30 parts of ginger, 30 parts of wolfberries, 15 parts of astragalus membranaceus, 60 parts of coptis chinensis, 15 parts of angelica sinensis, 20 parts of codonopsis pilosula, 30 parts of pearl powder, 15 parts of poria cocos, and 10 parts of turmeric.

[0022] Mix the herbal medicines evenly, add an appropriate amount of water, and put them into a stainless-steel pot or a porcelain casserole for decocting. Control the decocting temperature at about 120°C and the decocting time for 2 hours. Filter the medicinal powder to remove impurities and obtain pure medicinal powder. Fill the medicinal powder into a suitable container and seal it for storage. In this example, decocting the medicinal powder in a stainless-steel pot or a porcelain casserole makes the curative effect of the decocted medicinal powder more significant. When using, first remove the upper layer of gauze, then apply the well-stirred medicinal powder onto the gauze, cover it with another layer of gauze, and remove it after 30 to 60 minutes. Use it once a day, which has very good health care effects on myopia, presbyopia, astigmatism, amblyopia, photophobia, and epiphora in the wind.

[0023] Example Three:

[0024] The raw materials for preparing the medicine are 40 parts of cassia seeds, 10 parts of glossy privet fruits, 30 parts of chrysanthemums, 10 parts of Chinese yams, 10 parts of magnolia vines, 50 parts of peppermints, 20 parts of ginger, 20 parts of wolfberries, 105 parts of astragalus membranaceus, 50 parts of coptis chinensis, 10 parts of angelica sinensis, 15 parts of codonopsis pilosula, 25 parts of pearl powder, 10 parts of poria cocos, and 8 parts of curcuma aromatica; Mix the herbs evenly, add an appropriate amount of water, and decoct in a stainless-steel pot or a porcelain casserole until concentrated; Filter the medicinal powder to remove impurities and obtain pure medicinal powder. Fill the medicinal powder into a suitable container and seal it for storage. Before using the container, it needs to be cleaned and disinfected first to ensure the hygiene and safety of the decocted medicinal materials; The decocting time is 1 - 2 hours, and the decocting temperature is 100 - 120 °C. The filtering step includes pouring the medicinal powder into a filter, and the filter is made of gauze and filter paper. Pay attention to the tightness of the filter during filtering to avoid the loss of medicinal powder. After filtering, let the medicinal powder stand for a while again to make the remaining impurities precipitate to the bottom, pour the medicinal powder into a clean container, and use a funnel to avoid splashing of the medicinal powder; Finally, disinfect the container with an ultraviolet germicidal lamp and high-temperature disinfection to ensure the hygiene and safety of the medicinal powder. When using, first remove the upper layer of gauze, then apply the stirred medicinal powder onto the gauze, cover it with another layer of gauze, and remove it after 30 - 60 minutes. Use it once a day, which has a very good health care effect on myopia, presbyopia, astigmatism, amblyopia, photophobia, and epiphora in the wind.

[0025] Example 4:

[0026] The raw materials for preparing the medicine are 30 parts of cassia seeds, 15 parts of glossy privet fruits, 25 parts of chrysanthemums, 7 parts of Chinese yams, 8 parts of magnolia vines, 45 parts of peppermints, 18 parts of ginger, 15 parts of wolfberries, 103 parts of astragalus membranaceus, 48 parts of coptis chinensis, 8 parts of angelica sinensis, 13 parts of codonopsis pilosula, 25 parts of pearl powder, 10 parts of poria cocos, and 8 parts of curcuma aromatica

[0027] Prepare a cleaned and disinfected stainless-steel pot or porcelain casserole, and add the medicinal materials into the pot. Add an appropriate amount of clear water to cover the medicinal materials, and then heat to boiling. Adjust the heat and decoct the medicinal materials for 1 - 2 hours at a decocting temperature of 100 - 120 °C until the medicinal liquid is concentrated. Turn off the heat and let the medicinal liquid cool to room temperature. Pour the medicinal liquid into a filter, and the filter is made of gauze and filter paper. Pay attention to the tightness of the filter during filtering to avoid the loss of medicinal liquid. After filtering, let the medicinal liquid stand for a while again to make the remaining impurities precipitate to the bottom. Pour the medicinal liquid into a clean container, and use a funnel to avoid splashing of the medicinal liquid. Finally, disinfect the container with an ultraviolet germicidal lamp and high-temperature disinfection to ensure the hygiene and safety of the medicinal liquid. When using, first shake the medicinal liquid evenly, and apply it evenly around the eyes. Repeat five times a day, which has a very good health care effect on myopia, presbyopia, astigmatism, amblyopia, photophobia, and epiphora in the wind.

[0028] Example 5:

[0029] 40 parts of cassia seeds, 10 parts of glossy privet fruits, 30 parts of chrysanthemums, 10 parts of Chinese yams, 10 parts of magnoliavine fruits, 50 parts of mints, 20 parts of ginger, 20 parts of wolfberries, 10 parts of astragalus membranaceus, 50 parts of coptis chinensis, 10 parts of Chinese angelica, 20 parts of codonopsis pilosula, 30 parts of pearl powder, 10 parts of poria cocos, 10 parts of turmeric; Prepare a stainless steel pot or a porcelain casserole that has been cleaned and disinfected, and add the medicinal materials into the pot.

[0030] Add an appropriate amount of clean water to cover the medicinal materials, then heat to boiling, adjust the heat, decoct the medicinal materials for 1 - 2 hours, the decocting temperature is 100 - 120 °C, until the medicinal liquid is concentrated, turn off the heat, cool the medicinal liquid to room temperature, pour the medicinal liquid into a filter. The filter is made of gauze and filter paper. Pay attention to the tightness of the filter during filtration to avoid the loss of the medicinal liquid. After filtration, let the medicinal liquid stand for a period of time again to make the remaining impurities precipitate to the bottom, pour the medicinal liquid into a clean container, use a funnel to avoid splashing of the medicinal liquid. Finally, disinfect the container with an ultraviolet germicidal lamp and high-temperature disinfection to ensure the hygienic safety of the medicinal liquid.

[0031] When in use, first shake the medicinal liquid evenly, and apply it evenly around the eyes. Repeat five times a day. It has a very good health care effect on myopia, presbyopia, astigmatism, amblyopia, photophobia, and epiphora.

[0032] In this specification, each embodiment is described in a progressive manner. The key point of each embodiment is to illustrate the differences from other embodiments. The same or similar parts among the embodiments can be referred to each other. For the device disclosed in the embodiment, since it corresponds to the method disclosed in the embodiment, the description is relatively simple. For the relevant parts, refer to the description of the method part.

[0033] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be obvious to those skilled in the art. The general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to these embodiments shown herein, but will be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A novel ophthalmic drug, characterized in that, It comprises the following components by weight: 30 - 50 parts of semen cassiae, 5 - 15 parts of fructus ligustri lucidi, 20 - 40 parts of flos chrysanthemi, 5 - 15 parts of rhizoma dioscoreae, 5 - 15 parts of fructus schisandrae chinensis, 40 - 60 parts of herba menthae, 10 - 30 parts of rhizoma zingiberis recens, 10 - 30 parts of fructus lycii, 5 - 15 parts of radix astragali, 40 - 60 parts of rhizoma coptidis, 5 - 15 parts of radix angelicae sinensis, 10 - 20 parts of radix codonopsis pilosulae, 20 - 30 parts of pearl powder, 5 - 15 parts of poria cocos, and 5 - 10 parts of radix curcumae aromatica.

2. A preparation method of a novel ophthalmic drug, characterized in that, It comprises the following steps: a: Mix the components in Claim 1 evenly according to the ratio; b: Decoct the mixed medicinal materials with water until concentrated to obtain the medicine; c: Filter the medicine to remove impurities to obtain pure medicine; d: Fill the medicine into a suitable container and seal it for storage.

3. The preparation method of the novel ophthalmic drug according to claim 2, characterized in that, The container used for decocting is a stainless - steel pot or a porcelain casserole. Before using the container, it needs to be cleaned and disinfected to ensure the hygiene and safety of the decoction of the medicinal materials.

4. The preparation method of the novel ophthalmic drug according to claim 2, characterized in that, The decocting time is 1 - 2 hours and the decocting temperature is 100 - 120 °C.

5. The preparation method of the novel ophthalmic drug according to claim 2, characterized in that, The filtering step includes pouring the medicine into a filter. The filter is made of gauze and filter paper. Attention should be paid to the tightness of the filter during filtering to avoid the loss of medicine. After filtering, let the medicine stand for a period of time again to make the remaining impurities precipitate to the bottom. Pour the medicine into a clean container, using a funnel to avoid splashing of the medicine. Finally, disinfect the container with an ultraviolet germicidal lamp and high - temperature disinfection to ensure the hygiene and safety of the medicine.