Automatic magnetic drive sterile dish changing device and using method thereof

Through the magnetic field-driven automatic magnetic drive sterile disc replacement device, the pollution risk and system failure problems of the Petri dish replacement device are solved, automatic replacement and efficient operation in a sterile environment are achieved, and GMP regulations are met.

CN120249015APending Publication Date: 2025-07-04SHANGHAI TOFFLON SCI & TECH CO LTD
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Patent Information

Application Number
CN202510389011.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-31
Publication Date
2025-07-04

AI Technical Summary

Technical Problem

The existing Petri dish replacement device has contaminated channels between the clean area and the non-clean area, and the traditional method can easily lead to overall system failure, affecting the continuity and safety of the production environment.

Method used

The automatic magnetic drive sterile disc change device driven by magnetic field is adopted to automatically replace the petri dish by interacting with the magnetic field of the driving component and the bearing component. The pick-up component is combined with the pick-up component to perform the switching operation of the petri dish, avoiding the direct connection between the clean area and the non-clean area, and setting up multiple independent electromagnetic rings to interact with the permanent magnet to improve the reliability of the system.

Benefits of technology

It realizes automatic replacement of petri dishes in a sterile environment, avoids cross contamination, meets GMP regulations, improves the versatility and adaptability of equipment, reduces personnel work intensity, and improves production efficiency and operation safety and reliability.

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Abstract

The invention discloses an automatic magnetic drive sterile dish changing device and a using method thereof. The automatic magnetic drive sterile dish changing device comprises a supporting assembly, a driving assembly, a bearing assembly and a grabbing assembly. The driving assembly is arranged on the supporting assembly and used for generating a magnetic field. The bearing assembly is rotatably arranged on the supporting assembly and is used for bearing a culture dish; the bearing assembly interacts with a magnetic field generated by the driving assembly, so that the bearing assembly rotates around the supporting assembly; the grabbing assembly is installed on the supporting assembly and used for taking and placing the culture dishes and opening and closing the culture dish covers so that the culture dishes can be automatically replaced in the sterile environment. The culture dish can be automatically replaced in a sterile environment, and the pollution risk caused by manual intervention is avoided.
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Description

Technical Field

[0001] The present invention relates to the field of biological environment monitoring devices, and particularly to an automatic magnetic-driven sterile petri dish changing device and a method for using the same. Background Art

[0002] In the fields of pharmaceutical industry, medical research, laboratories, and food environment monitoring, petri dishes, as important tools for collecting biological particles, are widely used in the monitoring of clean environments. According to international and national pharmaceutical regulations, petri dishes used for evaluating the cleanliness of clean areas need to be exposed for more than 30 minutes in static tests and should not exceed 4 hours in dynamic tests. In actual production environments, petri dishes usually need to be replaced every 1 to 4 hours.

[0003] Existing petri dish changing devices generally adopt a direct drive method with a bottom motor. This design requires a communication hole to be opened between the clean area and the motor maintenance area, resulting in a pollution channel between the clean area and the non-clean area. When the motor needs to be repaired or replaced, it increases the risk of contamination of the clean environment, which does not meet the strict requirements of regulations such as GMP for production areas.

[0004] In addition, traditional petri dish changing devices usually adopt a storage method of stacking petri dishes. This structural design has obvious reliability problems. When one of the petri dishes gets stuck or fails, it will cause the entire petri dish changing process to interrupt, and subsequent petri dishes cannot be used continuously, seriously affecting the continuous monitoring of the production environment and even possibly leading to non-compliance in the production process.

[0005] With the continuous improvement of requirements for clean production areas by regulations such as GMP, reducing manual intervention and avoiding particle generation have become basic requirements for clean production areas such as isolators. The traditional manual method of changing petri dishes not only increases the workload of personnel but also increases the risk of contamination caused by human operation.

[0006] Therefore, there is an urgent need to propose an automatic magnetic-driven sterile petri dish changing device and a method for using the same to solve the above problems. Summary of the Invention

[0007] The purpose of the present invention is to propose an automatic magnetic-driven sterile petri dish changing device and a method for using the same, which can realize the automatic replacement of petri dishes in a sterile environment and avoid the pollution risk brought by manual intervention.

[0008] To solve the above technical problems, the present invention provides an automatic magnetic-driven sterile petri dish changing device, including a support assembly, a drive assembly, a carrier assembly, and a grasping assembly;

[0009] The drive assembly is arranged on the support assembly and is used to generate a magnetic field;

[0010] The carrying component is rotatably arranged on the supporting component and is used for carrying a culture dish;

[0011] The carrying component interacts with the magnetic field generated by the driving component, so that the carrying component rotates around the supporting component;

[0012] The grasping component is installed on the supporting component and is used for picking up and placing the culture dish and operating the opening and closing of the culture dish cover, so as to automatically replace the culture dish in a sterile environment.

[0013] Furthermore, the supporting component includes a device base, a support shaft and an end cover; the support shaft is located inside the device base, and one end of the support shaft extends outside the device base; the end cover is arranged at one end of the support shaft and is connected to the device base; the carrying component and the driving component are arranged on the side wall of the device base, and both the carrying component and the driving component are connected to the support shaft.

[0014] Furthermore, the driving component includes a plurality of guide rails and a plurality of electromagnetic rings; the guide rails are installed on the side wall of the device base and surround the support shaft; the plurality of electromagnetic rings are respectively arranged on the plurality of guide rails and are axially distributed along the support shaft; the electromagnetic rings generate a magnetic field with controllable magnetic poles after being energized; the plurality of carrying components are respectively located inside the plurality of electromagnetic rings and are arranged radially opposite to the corresponding electromagnetic rings, and drive the carrying components to rotate through magnetic field interaction.

[0015] Furthermore, the carrying component includes a disc, a disc rod, a disc handle and a permanent magnet; one end of the disc rod is connected to the disc, and the other end is connected to the disc handle; the disc handle is installed on the corresponding guide rail; the permanent magnet is installed in the disc handle and generates magnetic field interaction with the corresponding electromagnetic ring when energized.

[0016] Furthermore, the grasping component includes a cylinder arm, a cylinder, a cylinder rod and a grasping head; the fixed end of the cylinder arm is installed on the supporting component, and the telescopic end is connected to the cylinder; the cylinder rod is slidably arranged in the cylinder and makes a telescopic movement in the cylinder under the drive of the cylinder; the grasping head includes a fixed part and a rotating part, the fixed part is sleeved on the end of the cylinder rod far away from the cylinder, and the rotating part is connected to the fixed part through a bearing and can rotate relative to the fixed part.

[0017] Further, the grasping assembly further includes a plurality of grasping rods and a plurality of air nozzles; the fixed ends of the grasping rods are connected to the rotating part, and the free ends can move towards or away from the central axis direction of the grasping head to clamp or release the petri dish body; the air nozzles are arranged on the fixed part for adsorbing the petri dish cover; the plurality of grasping rods are annularly distributed around the air nozzles.

[0018] Further, springs are connected between the plurality of grasping rods or between the grasping rods and the grasping head.

[0019] Further, the other end of the grasping rod is connected with an inflatable sealing ring; the inflatable sealing ring can fasten the petri dish in the inflated state and release the petri dish in the deflated state.

[0020] In addition, the present invention also provides a usage method of the automatic magnetic drive sterile dish changing device, using the automatic magnetic drive sterile dish changing device as described above, which specifically includes the following:

[0021] Generate a magnetic field through the driving assembly to interact with the bearing assembly, so that the bearing assembly rotates around the support assembly to a specified station;

[0022] Pick up and place the petri dish through the grasping assembly and perform the opening and closing operations on the petri dish cover; and

[0023] After the petri dish is exposed for a predetermined time, cover the petri dish cover through the grasping assembly, and at the same time drive another bearing assembly through the driving assembly to drive a new petri dish to move to the specified station to complete the automatic replacement of all petri dishes.

[0024] Further, the picking up and placing of the petri dish through the grasping assembly and the opening and closing operations on the petri dish cover specifically include: fixing the petri dish body through the inflatable sealing ring of the grasping assembly, adsorbing the petri dish cover through the air nozzle of the grasping assembly, and moving the petri dish cover away from the petri dish body; when the petri dish cover and the petri dish body are threadedly connected, unscrew the petri dish cover through the rotating action of the grasping assembly and move the petri dish cover away from the petri dish body.

[0025] Through the above technical solutions, the present invention has the following beneficial effects:

[0026] By adopting the driving method through the magnetic field interaction between the driving component and the bearing component, and setting the grasping component to perform the picking and placing of the culture dish and the opening and closing operation of the lid, this device realizes the automatic replacement of the culture dish in a sterile environment. In addition, this device can avoid the drawback of the traditional device that requires opening holes in the clean area to connect the motor, effectively isolates the clean area from the non-clean area, prevents cross-contamination, and ensures the integrity of the sterile environment. At the same time, the support component provides a stable basic structure for the device, enabling the entire dish-changing process to proceed stably and reliably, meeting the strict requirements of regulations such as GMP for isolator production.

[0027] In addition, by setting the driving method of the interaction between multiple independent electromagnetic rings and permanent magnets, and the innovative grasping mechanism setting, this device can solve the problem that a single-point failure in the traditional dish-changing device affects the overall system. The grasping mechanism combining the inflatable sealing ring and the air nozzle can adapt to the operation requirements of different types of culture dishes, including the handling of the threaded-connection type culture dish lid, improving the versatility and adaptability of the equipment. The setting of the grasping component can achieve the precise positioning and operation of the culture dish, improve the safety and reliability of aseptic operation, and at the same time can reduce the labor intensity of personnel and improve production efficiency. Brief Description of the Drawings

[0028] Figure 1 is the front view of the automatic magnetic drive sterile dish-changing device in an embodiment of the present invention;

[0029] Figure 2 is Figure 1 the cross-sectional view in the A-A direction of

[0030] Figure 3 is the overall structural schematic diagram of the automatic magnetic drive sterile dish-changing device in an embodiment of the present invention;

[0031] Figure 4 is the top view of the automatic magnetic drive sterile dish-changing device in an embodiment of the present invention;

[0032] Figure 5 is the top view of the bearing component in the automatic magnetic drive sterile dish-changing device in an embodiment of the present invention;

[0033] Figure 6 is the structural schematic diagram of the grasping component in the automatic magnetic drive sterile dish-changing device in an embodiment of the present invention;

[0034] Figure 7 is the flowchart of the usage method of the automatic magnetic drive sterile dish-changing device in an embodiment of the present invention.

[0035] In the figure, 11 is the device base; 12 is the support shaft; 13 is the end cover; 21 is the guide rail; 22 is the electromagnetic ring; 3 is the carrying assembly; 31 is the disc; 32 is the disc rod; 33 is the disc handle; 34 is the permanent magnet; 41 is the cylinder arm; 42 is the cylinder; 43 is the cylinder rod; 44 is the gripping head; 45 is the gripping rod; 46 is the air nozzle; 47 is the inflatable sealing ring; 5 is the culture dish; 6 is the disc table; 7 is the clamping device. Detailed implementation mode

[0036] The following will describe in more detail an automatic magnetic drive sterile disc-changing device and its usage method according to the present invention with reference to the accompanying drawings, in which the preferred embodiments of the present invention are shown. It should be understood that those skilled in the art can modify the present invention described herein while still achieving the advantageous effects of the present invention. Therefore, the following description should be understood as a broad guidance for those skilled in the art and not as a limitation to the present invention.

[0037] In the following paragraphs, the present invention will be described more specifically by way of example with reference to the accompanying drawings. The advantages and features of the present invention will be clearer according to the following description. It should be noted that the accompanying drawings are all in a very simplified form and use non-precise scales, only for the purpose of conveniently and clearly assisting in explaining the embodiments of the present invention.

[0038] As Figures 1 - 3 shown, an embodiment of the present invention provides an automatic magnetic drive sterile disc-changing device, which includes a support assembly, a drive assembly, a carrying assembly 3, and a gripping assembly.

[0039] Specifically, the drive assembly is arranged on the support assembly and is used to generate a magnetic field; the carrying assembly 3 is rotatably arranged on the support assembly and is used to carry the culture dish 5; the carrying assembly 3 interacts with the magnetic field generated by the drive assembly, so that the carrying assembly 3 rotates around the support assembly; the gripping assembly is installed on the support assembly and is used to pick up and place the culture dish 5 and perform the opening and closing operations on the culture dish cover, so as to automatically replace the culture dish 5 in a sterile environment. This structural arrangement enables the driving force to be transmitted through magnetic field interaction, avoiding the problem of opening holes to connect the driving motor between the clean area and the non-clean area, enhancing the integrity of the sterile environment, and reducing the pollution risk.

[0040] In one embodiment, the support assembly includes a device base 11, a support shaft 12, and an end cap 13. Specifically, the support shaft 12 is located inside the device base 11, and one end of the support shaft 12 extends outside the device base 11; the end cap 13 is disposed at one end of the support shaft 12 and is connected to the device base 11; the carrier assembly 3 and the drive assembly are disposed on the side wall of the device base 11, and both the carrier assembly 3 and the drive assembly are connected to the support shaft 12. This structural arrangement of the support assembly provides a stable infrastructure, enabling the carrier assembly 3 and the drive assembly to perform relative movements reliably, and enhancing the mechanical stability of the entire device.

[0041] In one embodiment, in combination Figure 2 with Figure 4 as shown, the drive assembly includes a plurality of guide rails 21 and a plurality of electromagnetic rings 22. Specifically, the guide rails 21 are installed on the side wall of the device base 11 and surround the support shaft 12; a plurality of the electromagnetic rings 22 are respectively disposed on a plurality of the guide rails 21 and are axially distributed along the support shaft 12; after the electromagnetic rings 22 are energized, a magnetic field with controllable magnetic poles is generated; a plurality of the carrier assemblies 3 are respectively located inside a plurality of the electromagnetic rings 22, are radially opposite to the corresponding electromagnetic rings 22, and drive the carrier assembly 3 to rotate through magnetic field interaction.

[0042] In a specific example, the electromagnetic ring 22 can adopt a structure of a coil wound around an iron core, and a magnetic field is generated by passing an electric current through the coil. By changing the direction of the electric current, the magnetic field polarity can be changed, thereby controlling the rotation direction and speed of the carrier assembly 3. Those skilled in the art will know that the number of the electromagnetic rings 22 can be set according to actual needs, and there are also other number selections besides this embodiment. This setting of independent control of a plurality of electromagnetic rings 22 enables a plurality of carrier assemblies 3 to be independently driven, improving the flexibility and reliability of the system. Even if a single electromagnetic ring 22 fails, it will not affect the normal use of other culture dishes 5. In addition, there are various options for the power-on method of the electromagnetic ring 22, including but not limited to pulse control and PWM modulation, etc., to achieve precise control of the rotation speed and position of the carrier assembly 3.

[0043] In one embodiment, in combination Figure 1 with Figure 2 and Figure 3 as well as Figure 5 as shown, the carrier assembly 3 includes a disc 31, a disc rod 32, a disc handle 33, and a permanent magnet 34. Specifically, one end of the disc rod 32 is connected to the disc 31, and the other end is connected to the disc handle 33; the disc handle 33 is installed on the corresponding guide rail 21; the permanent magnet 34 is installed in the disc handle 33 and generates magnetic field interaction with the corresponding electromagnetic ring 22 when energized.

[0044] In a specific example, the permanent magnet 34 can be made of high-performance permanent magnetic materials such as neodymium iron boron, having strong magnetic properties and stability. The disc 31 can be set to a shape matching the petri dish 5 to stably carry the petri dish 5. When the electromagnetic ring 22 is energized to generate a magnetic field, the permanent magnet 34 will be subjected to an attractive or repulsive force, driving the entire carrier assembly 3 to rotate on the guide rail 21, realizing the positioning movement of the petri dish 5. This setting of the carrier assembly 3 enables the petri dish 5 to be stably placed and accurately positioned, improving the reliability and accuracy of the disc changing process.

[0045] In this embodiment, in combination with Figure 1 , Figure 2 , Figure 3 and Figure 6 as shown, the grasping assembly includes a cylinder arm 41, a cylinder 42, a cylinder rod 43 and a grasping head 44. Specifically, the fixed end of the cylinder arm 41 is mounted on the support assembly, and the telescopic end is connected to the cylinder 42; the cylinder rod 43 is slidably disposed in the cylinder 42 and performs a telescopic action in the cylinder 42 under the drive of the cylinder 42; the grasping head 44 includes a fixed part and a rotating part, the fixed part is sleeved on the end of the cylinder rod 43 away from the cylinder 42, and the rotating part is connected to the fixed part through a bearing and can rotate relative to the fixed part.

[0046] In a specific example, the cylinder 42 can adopt a pneumatic or hydraulic drive mode, and the cylinder arm 41 can adopt a multi-joint design to enhance the flexibility of the grasping assembly. This structural setting of the grasping assembly provides a flexible movement range and precise operation ability, enhancing the accuracy and reliability of the operation of the petri dish 5.

[0047] In this embodiment, the grasping assembly further includes a plurality of grasping rods 45 and a plurality of air nozzles 46. Specifically, the fixed end of the grasping rod 45 is connected to the rotating part, and the free end can move towards or away from the central axis direction of the grasping head 44 to clamp or release the petri dish body; the air nozzles 46 are disposed on the fixed part for adsorbing the petri dish cover; the plurality of grasping rods 45 are annularly distributed around the air nozzles 46.

[0048] In a specific example, the air nozzles 46 can be connected to a negative pressure device to fix the petri dish cover by vacuum adsorption. The grasping rods 45 can be evenly distributed around the grasping head 44 to make the clamping force evenly distributed. This setting of the grasping assembly can handle the petri dish body and the petri dish cover simultaneously, improving the operation efficiency and flexibility.

[0049] Preferably, springs (not shown in the figure for simplicity of illustration) are connected between multiple said grasping rods 45 or between the grasping rod 45 and the grasping head 44. The elastic force of the springs can be adjusted according to the weight of the petri dish 5, which can not only provide sufficient grasping force but also cause no damage to the petri dish 5. The arrangement of connecting springs endows the grasping rod 45 with certain elasticity, enhances the adaptability to petri dishes 5 of different sizes, reduces the impact force that may be generated during the grasping process, and improves the stability and safety of the grasping process.

[0050] Preferably, the other end of the grasping rod 45 is connected with an inflatable sealing ring 47; the inflatable sealing ring 47 can fasten the petri dish 5 in the inflated state and release the petri dish 5 in the deflated state. In a specific example, the inflation and deflation inside the sealing ring can be controlled by a micro air pump to adjust the softness and hardness of the sealing ring and the grasping force. This arrangement of the inflatable sealing ring 47 can not only adapt to petri dishes 5 of different shapes and materials, but also provide uniform clamping force, reduce the damage to the petri dish 5, and improve the reliability and stability of the grasping.

[0051] In addition, as Figure 7 shown, this embodiment also proposes a usage method of the automatic magnetic drive sterile dish-changing device. Using the automatic magnetic drive sterile dish-changing device as described above, it specifically includes the following steps:

[0052] S1. Generate a magnetic field through the driving component to interact with the bearing component 3, so that the bearing component 3 rotates around the support component to a specified working position;

[0053] S2. Pick up and place the petri dish 5 through the grasping component and perform the opening and closing operations on the petri dish cover; and

[0054] S3. After the petri dish 5 is exposed for a predetermined time, cover the petri dish cover through the grasping component, and at the same time drive another bearing component 3 through the driving component to drive a new petri dish 5 to move to the specified working position to complete the automatic replacement of all petri dishes 5.

[0055] In step S2, the operation of picking up and placing the petri dish 5 through the grasping component and performing the opening and closing operations on the petri dish cover specifically includes: fixing the petri dish body through the inflatable sealing ring 47 of the grasping component, adsorbing the petri dish cover through the air nozzle 46 of the grasping component, and moving the petri dish cover away from the petri dish body; when the petri dish cover and the petri dish body are in a threaded connection, unscrew the petri dish cover through the rotational movement of the grasping component and move the petri dish cover away from the petri dish body.

[0056] In this embodiment, after the device is started, the first electromagnetic ring 22 is first activated to generate a magnetic field, which interacts with the permanent magnet 34 in the corresponding carrier assembly 3 to drive the carrier assembly 3 to rotate to the first station. The gripping assembly moves above the target petri dish 5 at the first station under the drive of the cylinder arm 41. The cylinder 42 drives the cylinder rod 43 to extend downward, bringing the gripping head 44 closer to the petri dish 5. The plurality of gripping rods 45 are initially deployed around the edge of the petri dish body. Subsequently, the inflatable sealing ring 47 is inflated to form an annular clamping force to firmly fix the petri dish body (the gripping rods 45 will rotate according to the size of the petri dish 5 and move closer to each other to improve the fixation of the petri dish 5). At the same time, the air nozzle 46 in the center of the gripping head 44 contacts the central area of the petri dish lid, generating a suction force to adsorb and fix the petri dish lid.

[0057] Subsequently, the cylinder rod 43 contracts to drive the gripping head 44 to rise, thereby driving the petri dish 5 to rise to a suitable position. The cylinder arm 41 extends to drive the cylinder 42 to move, thereby driving the cylinder rod 43, the gripping head 44 and the petri dish 5 to move to the second station. At this time, the cylinder rod 43 extends to drive the gripping head 44 and the petri dish 5 to descend to the dish table 6. The dish table 6 is provided with a clamping device 7. After the clamping device 7 fixes the petri dish body, the inflatable sealing ring 47 on the gripping rod 45 deflates. After the deflation is completed, the cylinder rod 43 extends a certain amount so that the inflatable sealing ring 47 is separated from contact with the petri dish body and the air nozzle 46 fully adsorbs on the petri dish lid.

[0058] Throughout the process, the fixed ends of the gripping rods 45 are connected to the rotating part of the gripping head 44, and the free ends can move toward or away from the central axis direction of the gripping head 44 to clamp or release the petri dish body. The plurality of gripping rods 45 are annularly distributed around the air nozzle 46 and are connected by springs to ensure an appropriate clamping force. The air nozzle 46 is arranged on the fixed part of the gripping head 44 and is specifically used for adsorbing the petri dish lid to ensure stable operation during the opening and closing of the petri dish 5. The inflatable sealing ring 47 connected to the free end of the gripping rod 45 can fasten the petri dish body in the inflated state and release the petri dish body in the deflated state, realizing reliable grasping and releasing of the petri dish body.

[0059] When the petri dish lid and the petri dish body are threadedly connected. After the clamping device 7 on the dish table 6 fixes the petri dish body, the air nozzle 46 adsorbs and fixes the center of the petri dish lid. At this time, the rotating part of the gripping head 44 is connected to the fixed part through a bearing and can rotate relative to the fixed part. The rotating part of the gripping head 44 starts to rotate driven by the driving mechanism, while the fixed part remains stationary. Since the air nozzle 46 is arranged on the fixed part, the petri dish lid is stably adsorbed by the air nozzle 46; at the same time, the clamping device 7 firmly fixes the petri dish body, and this cooperation makes the petri dish body rotate relative to the petri dish lid, gradually loosening the threaded connection.

[0060] When the thread is completely loosened, the cylinder rod 43 contracts, driving the gripping head 44 to rise. The air nozzle 46 continues to adsorb the culture dish lid, completely detaching it from the culture dish body. The cylinder arm 41 contracts, driving the cylinder 42, cylinder rod 43, gripping head 44, and culture dish lid back to the first station. Meanwhile, the culture dish body remains on the dish table 6 at the second station, exposed to the environment for microbial sampling. Through the cooperation of the air nozzle 46 and the clamping device 7, the automatic opening and closing operations of the threaded culture dish 5 are ingeniously realized without manual intervention, ensuring that the entire process is completed under aseptic conditions.

[0061] After the culture dish 5 has been exposed for a predetermined time, the gripping assembly will operate in the reverse order to re-cover the culture dish lid onto the culture dish body. For the threaded culture dish 5, the rotating part of the gripping head 44 will rotate in the reverse direction, driving the culture dish body to rotate relative to the culture dish lid to re-tighten the two.

[0062] In practical applications, this device is also equipped with a vision detection module that can monitor the position and lid-opening state of the culture dish 5 in real time to ensure the accuracy of each operation. At the same time, this device is also equipped with a control system that will automatically adjust parameters such as the gripping force, rotation angle, and speed according to the types and specifications of different culture dishes 5 to meet different experimental requirements.

[0063] As is known to those skilled in the art, the operating parameters of the gripping assembly can be adjusted according to the characteristics of different specifications of the culture dish 5 to meet the requirements of different production environments. For example, for lighter and smaller culture dishes 5, the pressure of the cylinder 42 and the inflation pressure of the inflatable sealing ring 47 can be reduced; for culture dishes 5 with finer threads, the rotation speed of the rotating part can be reduced and the number of rotation turns can be increased to ensure that the threads can be completely loosened without damaging the culture dish 5.

[0064] In summary, an automatic magnetic drive aseptic dish-changing device and its usage method proposed by the present invention have the following advantages:

[0065] By using the magnetic field interaction between the drive assembly and the bearing assembly for driving, and setting up a gripping assembly for the picking and placing of the culture dish and the opening and closing of the lid, this device realizes the automatic replacement of the culture dish in an aseptic environment. In addition, this device can avoid the drawback of the traditional device that requires opening holes in the clean area to connect the motor, effectively isolating the clean area from the non-clean area, preventing cross-contamination, and ensuring the integrity of the aseptic environment. At the same time, the support assembly provides a stable basic structure for the device, enabling the entire dish-changing process to proceed stably and reliably, meeting the strict requirements of regulations such as GMP for isolator production.

[0066] In addition, by setting the driving mode of multiple independent electromagnetic rings interacting with permanent magnets and the innovative grasping mechanism, this device can solve the problem that a single-point failure in the traditional disc-changing device affects the overall system. The grasping mechanism combining an inflatable sealing ring and a nozzle can adapt to the operation requirements of different types of petri dishes, including the handling of screw-connected petri dish lids, improving the versatility and adaptability of the equipment. The setting of the grasping component can achieve precise positioning and operation of the petri dish, improving the safety and reliability of aseptic operation, while reducing the labor intensity of personnel and enhancing production efficiency.

[0067] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention is also intended to include these changes and modifications.

Claims

1. An automatic magnetic drive sterile dish-changing device, characterized in that, It includes a support component, a drive component, a carrier component (3), and a grasping component; The drive component is arranged on the support component and is used to generate a magnetic field; The carrier component (3) is rotatably arranged on the support component and is used to carry a culture dish (5); The carrier component (3) interacts with the magnetic field generated by the drive component, causing the carrier component (3) to rotate around the support component; The grasping component is installed on the support component and is used to pick up and place the culture dish (5) and perform the opening and closing operations on the culture dish cover, so as to automatically replace the culture dish (5) in a sterile environment.

2. The automatic magnetic drive sterile dish changing device according to claim 1, wherein The support component includes a device base (11), a support shaft (12), and an end cover (13); the support shaft (12) is located inside the device base (11), and one end of the support shaft (12) extends outside the device base (11); the end cover (13) is arranged at one end of the support shaft (12) and is connected to the device base (11); the carrier component (3) and the drive component are arranged on the side wall of the device base (11), and both the carrier component (3) and the drive component are connected to the support shaft (12).

3. The automatic magnetic drive sterile dish-changing device according to claim 2, wherein The drive component includes a plurality of guide rails (21) and a plurality of electromagnetic rings (22); the guide rails (21) are installed on the side wall of the device base (11) and surround the support shaft (12); a plurality of the electromagnetic rings (22) are respectively arranged on a plurality of the guide rails (21) and are axially distributed along the support shaft (12); the electromagnetic rings (22) generate a magnetic field with controllable magnetic poles after being energized; a plurality of the carrier components (3) are respectively located inside a plurality of the electromagnetic rings (22), are radially opposite to the corresponding electromagnetic rings (22), and drive the carrier component (3) to rotate through magnetic field interaction.

4. The automatic magnetic drive sterile dish changing device according to claim 3, wherein The carrier component (3) includes a disc (31), a disc rod (32), a disc handle (33), and a permanent magnet (34); one end of the disc rod (32) is connected to the disc (31), and the other end is connected to the disc handle (33); the disc handle (33) is installed on the corresponding guide rail (21); the permanent magnet (34) is installed in the disc handle (33) and generates magnetic field interaction with the corresponding electromagnetic ring (22) when energized.

5. The automatic magnetic drive sterile dish changing device according to claim 1, characterized in that The grasping component includes a cylinder arm (41), a cylinder (42), a cylinder rod (43), and a grasping head (44); the fixed end of the cylinder arm (41) is installed on the support component, and the telescopic end is connected to the cylinder (42); the cylinder rod (43) is slidably arranged in the cylinder (42) and performs telescopic movements in the cylinder (42) under the drive of the cylinder (42); the grasping head (44) includes a fixed part and a rotating part, the fixed part is sleeved on the end of the cylinder rod (43) away from the cylinder (42), and the rotating part is connected to the fixed part through a bearing and can rotate relative to the fixed part.

6. The automatic magnetic drive sterile dish changing device according to claim 5, wherein, The gripping assembly further includes a plurality of gripping rods (45) and a plurality of air nozzles (46); the fixed ends of the gripping rods (45) are connected to the rotating part, and the free ends can move towards or away from the central axis direction of the gripping head (44) to clamp or release the petri dish body; the air nozzles (46) are arranged on the fixed part for adsorbing the petri dish cover; the plurality of gripping rods (45) are annularly distributed around the air nozzles (46).

7. The automatic magnetic drive sterile dish changing device according to claim 6, characterized in that, A spring is connected between the plurality of gripping rods (45) or between the gripping rod (45) and the gripping head (44).

8. The automatic magnetic drive sterile dish changing device according to claim 6, wherein, The other end of the gripping rod (45) is connected with an inflatable sealing ring (47); the inflatable sealing ring (47) can fasten the petri dish (5) in the inflated state and release the petri dish (5) in the deflated state.

9. A method for using an automatic magnetic drive sterile dish changing device, using the automatic magnetic drive sterile dish changing device according to any one of claims 1-8, characterized in that, Specifically, it includes the following: By generating a magnetic field through the driving assembly to interact with the bearing assembly (3), the bearing assembly (3) is rotated around the support assembly to a specified working position; By the gripping assembly, the petri dish (5) is picked up and placed, and the opening and closing operations of the petri dish cover are performed; and After the petri dish (5) is exposed for a predetermined time, the petri dish cover is covered back by the gripping assembly, and at the same time, another bearing assembly (3) is driven by the driving assembly to drive a new petri dish (5) to move to the specified working position to complete the automatic replacement of all petri dishes (5).

10. The method of using the automatic magnetic drive sterile dish-changing device according to claim 9, characterized in that, The operation of picking up and placing the petri dish (5) and opening and closing the petri dish cover by the gripping assembly specifically includes: fixing the petri dish body by the inflatable sealing ring (47) of the gripping assembly, adsorbing the petri dish cover by the air nozzle (46) of the gripping assembly, and moving the petri dish cover away from the petri dish body; when the petri dish cover and the petri dish body are threadedly connected, the petri dish cover is unscrewed by the rotating action of the gripping assembly, and the petri dish cover is moved away from the petri dish body.