Hepatitis B virus surface antigen detection device

Abstract

The invention relates to the technical field of antigen detection, and provides a hepatitis B virus surface antigen detection device, which comprises a detection table and a door body, the top of the detection table is provided with a first built-in cavity, and the interior of the detection table below the first built-in cavity is provided with a second built-in cavity. By arranging a fixing structure, a test tube with a to-be-detected reagent is moved between spring pieces to be pressed downwards, the test tube can be clamped under the action of the spring pieces, the test tube is prevented from displacing in a fixing cylinder, at the moment, a clamping block is moved into a movable groove, and under the elastic force action of a second reset spring, the test tube can be clamped in the movable groove. A clamping block is moved into a clamping groove, a test tube is pressed, a reset plate and a fixing cylinder are separated from each other, under the elastic force action of a first reset spring, the reset plate drives the test tube to move upwards through a spring piece, the test tube is conveniently taken out, and the function that the device is convenient to fix is achieved; therefore, the applicability of the hepatitis B virus surface antigen detection device in use is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of antigen detection, and particularly relates to a hepatitis B virus surface antigen detection device. Background Art

[0002] The hepatitis B virus surface antigen detection device is one of the important tools for the diagnosis of hepatitis B virus infection. Through different detection methods, it can observe and judge whether there is hepatitis B virus surface antigen in the sample, providing an important reference for the diagnosis and treatment of hepatitis B virus infection. Therefore, a hepatitis B virus surface antigen detection device is used;

[0003] For this reason, the patent with the authorization announcement number CN111220798A discloses an antigen detection device, including a base and a carrier plate. The carrier plate is rotatably installed on the upper part of the base. A plurality of sleeves are installed on the top of the carrier plate along the circumferential direction, and the openings of the sleeves face upward. A load-bearing plate is rotatably installed on the top of the carrier plate. A detachable vertical rod is vertically installed on the top of the load-bearing plate, and a plurality of clamping mechanisms are installed outside the vertical rod. By dropping the reagents required for detection into each holding device, the reagent addition is convenient and fast. A plurality of detection samples at the bottom can simultaneously detect multiple antigens. During the detection, the reagent can move and stop freely, and the position adjustment is convenient and fast, which can adapt to different working requirements and improve the working efficiency;

[0004] Although the above-mentioned antigen detection device can move and stop freely during the detection, and the position adjustment is convenient and fast, and it can adapt to different working requirements, when in use, due to its inconvenience in fixing, the stability is poor when fixing the test tube, and it is also inconvenient to take, resulting in low applicability when in use. Summary of the Invention

[0005] The purpose of the present invention is to provide a hepatitis B virus surface antigen detection device to solve the defect that the existing hepatitis B virus surface antigen detection device is inconvenient to fix.

[0006] To solve the above technical problems, the present invention provides the following technical solution: A hepatitis B virus surface antigen detection device, including a detection table and a door body;

[0007] A first built-in cavity is provided at the top of the detection table. A second built-in cavity is opened inside the detection table below the first built-in cavity. A door body is installed on the outer wall of the detection table on one side of the second built-in cavity. A turntable is arranged inside the first built-in cavity. Fixed structures are evenly fixed at the top of the turntable. The fixed structure includes a fixed cylinder, a first return spring, a return plate, a spring piece, a clamping groove, a movable groove, a second return spring and a clamping block. The fixed cylinders are evenly fixed at the top of the turntable. The first return springs are fixed to the bottoms of the fixed cylinders. Clamping grooves are evenly opened on both sides inside the fixed cylinders. The first return springs are fixed to the tops of the return plates. The spring pieces are fixed to the tops of the return plates. Movable grooves are opened on both sides inside the return plates. The second return springs are arranged inside the movable grooves. One ends of the second return springs are fixed to the clamping blocks. Test tubes are arranged inside the fixed structures.

[0008] A through groove penetrates through the inside of the turntable. A support penetrates through the inside of the through groove. A moving structure is arranged at the top of the support.

[0009] A rotating structure is arranged inside the first built-in cavity on one side of the turntable. A fixed seat is fixed to one side of the top of the detection table. A luminescence analyzer is arranged on one side of the top of the fixed seat.

[0010] When using this device, by setting the fixed structure, the function of facilitating fixation of this device is realized, thereby improving the applicability of this hepatitis B surface antigen detection device during use; by setting the moving structure, the function of facilitating the reduction of bacteria of this device is realized, thereby improving the stability of this hepatitis B surface antigen detection device during use; by setting the rotating structure, the function of facilitating continuous detection of this device is realized, thereby improving the working efficiency of this hepatitis B surface antigen detection device during use.

[0011] Preferably, the turntable and the detection table form a rotating structure. The top of the turntable and the top of the detection table are located on the same horizontal plane. The bottom end of the support is fixedly connected to the inner wall of the detection table.

[0012] Preferably, the return plate and the spring piece form a telescopic structure through the first return spring. The clamping block, the fixed cylinder and the clamping groove form a clamping structure. Move the test tube with the reagent to be detected between the spring pieces and press downwards, so that the spring piece drives the return plate to move downwards. Under the action of the spring piece, the test tube can be clamped to prevent the test tube from displacing inside the fixed cylinder. At this time, the clamping block moves into the movable groove. Under the elastic force of the second return spring, the clamping block moves into the clamping groove, and then the return plate and the fixed cylinder are fixed to each other.

[0013] Preferably, the front view section of the spring piece is designed in a "V" shape, and the inner side of the spring piece abuts against the outer side of the test tube. Press the test tube to separate the reset plate from the fixed cylinder. Under the elastic force of the first reset spring, the reset plate drives the test tube to move upward through the spring piece, facilitating the removal of the test tube.

[0014] Preferably, the moving structure includes an electric push rod, a tank body, a sealing cover, a movable plate, a fixed plate, an infrared sensor, a dropper, a solenoid valve, and a hose. The electric push rod penetrates through one side of the top of the support, and a tank body is fixed to the top of the support on one side of the electric push rod. The outer side of the top of the tank body is threadedly connected with a sealing cover.

[0015] Preferably, the bottom end of the electric push rod is fixed with a movable plate, one side of the movable plate is fixed with a fixed plate, and an infrared sensor is installed on one side of the bottom of the fixed plate.

[0016] Preferably, a dropper penetrates through one side of the inside of the movable plate, a solenoid valve is installed on the outside of the dropper, and a hose is fixed to one side of the top of the dropper. Under the action of the infrared sensor, the fixed cylinder drives the test tube to move below the dropper. Start the electric push rod, and the electric push rod drives the movable plate to move downward, and the movable plate drives the dropper to move to the top of the test tube.

[0017] Preferably, the end of the hose away from the dropper passes through the support and is communicated with one side of the bottom of the tank body, and the hose and the support form a sliding structure. Under the action of the solenoid valve, the enzyme reagent inside the tank body enters the inside of the dropper through the hose, and then enters the inside of the test tube to combine with the reagent to be detected. By moving the dropper to the top of the test tube, the contact between the enzyme reagent and the air can be reduced, so as to improve the detection accuracy.

[0018] Preferably, the rotating structure includes a gear, teeth, and a driving motor. The gear is arranged inside the first built-in cavity on one side of the turntable, teeth are uniformly fixed on the outer side of the bottom of the turntable, and a driving motor is installed on the top of the second built-in cavity below the gear. Start the driving motor, and the driving motor drives the gear to rotate inside the first built-in cavity, and the gear drives the turntable to rotate inside the first built-in cavity through the teeth.

[0019] Preferably, the gear and the tooth are meshed and connected, and the output end of the driving motor extends into the interior of the first built-in cavity and is fixedly connected to the bottom end of the gear. The turntable drives the fixed cylinder to rotate, so that the fixed cylinder moves below the dropper and below the luminescence analyzer for continuous detection. When the test tube is moved below the dropper to combine with the enzyme reagent, an antigen-enzyme complex is formed. This complex can catalyze the substrate to show in subsequent reactions. The test tube added with the enzyme reagent is moved below the luminescence analyzer. Under the action of the luminescence analyzer, the reagent to be detected and the enzyme reagent inside the test tube react to produce a chemiluminescence phenomenon, and the concentration of the reagent antigen inside the test tube is judged by measuring the luminescence signal.

[0020] An apparatus for detecting hepatitis B virus surface antigen provided by the present invention has the following advantages:

[0021] By providing a fixing structure, the test tube with the reagent to be detected is moved between the spring pieces and pressed downwards, so that the spring pieces drive the reset plate to move downwards. Under the action of the spring pieces, the test tube can be clamped to prevent the test tube from displacing inside the fixed cylinder. At this time, the clamping block moves into the movable groove, and under the elastic force of the second reset spring, the clamping block moves into the clamping groove, so that the reset plate and the fixed cylinder are fixed to each other. Press the test tube to separate the reset plate from the fixed cylinder. Under the elastic force of the first reset spring, the reset plate drives the test tube to move upwards through the spring pieces, which is convenient for taking out the test tube, realizing the function that the device is convenient to fix, thereby improving the applicability of the hepatitis B virus surface antigen detection device when in use;

[0022] By providing a moving structure, under the action of the infrared sensor, the fixed cylinder drives the test tube to move below the dropper. The electric push rod is started, and the electric push rod drives the movable plate to move downwards. The movable plate drives the dropper to move to the top of the test tube. Under the action of the solenoid valve, the enzyme reagent in the tank body enters the interior of the dropper through the hose, and then enters the interior of the test tube to combine with the reagent to be detected. By moving the dropper to the top of the test tube, the contact between the enzyme reagent and the air can be reduced to improve the detection accuracy, realizing the function that the device is convenient to reduce bacteria, thereby improving the stability of the hepatitis B virus surface antigen detection device when in use;

[0023] By providing a rotating structure, the driving motor is started, the driving motor drives the gear to rotate inside the first built-in cavity, the gear drives the turntable to rotate inside the first built-in cavity through the teeth, the turntable drives the fixed cylinder to rotate, so that the fixed cylinder moves below the dropper and below the luminescence analyzer for continuous detection, realizing the function that the device is convenient for continuous detection, thereby improving the working efficiency of the hepatitis B virus surface antigen detection device when in use. Description of the Drawings

[0024] Figure 1Three-dimensional first perspective schematic diagram of the present invention;

[0025] Figure 2 Three-dimensional front view sectional schematic diagram of the present invention;

[0026] Figure 3 Three-dimensional side view sectional schematic diagram of the present invention;

[0027] Figure 4 Three-dimensional sectional schematic diagram of the fixing structure of the present invention;

[0028] Figure 5 For the present invention Figure 4 Enlarged schematic diagram at position A in;

[0029] Figure 6 Three-dimensional sectional schematic diagram of the moving structure of the present invention;

[0030] Figure 7 Three-dimensional bottom view schematic diagram of the moving structure of the present invention;

[0031] Figure 8 Three-dimensional schematic diagram of the rotating structure of the present invention;

[0032] Figure 9 Three-dimensional sectional schematic diagram of the rotating structure of the present invention;

[0033] Figure 10 Three-dimensional second perspective schematic diagram of the present invention.

[0034] Explanation of reference numerals in the figure: 1. Detection table; 2. Door body; 3. Turntable; 4. Fixing structure; 401. Fixed cylinder; 402. First return spring; 403. Return plate; 404. Spring piece; 405. Clamping groove; 406. Activity groove; 407. Second return spring; 408. Clamping block; 5. Test tube; 6. Support; 7. Moving structure; 701. Electric push rod; 702. Tank body; 703. Sealing cover; 704. Movable plate; 705. Fixed plate; 706. Infrared sensor; 707. Dropper; 708. Solenoid valve; 709. Hose; 8. Fixed seat; 9. Rotating structure; 901. Gear; 902. Teeth; 903. Driving motor; 10. Luminescence analyzer; 11. First inner cavity; 12. Second inner cavity; 13. Through groove. Detailed implementation manners

[0035] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0036] Please refer to Figures 1 - 10 , a hepatitis B surface antigen detection device provided by the present invention includes a detection table 1 and a door body 2. A first built-in cavity 11 is provided at the top of the detection table 1. A second built-in cavity 12 is opened inside the detection table 1 below the first built-in cavity 11. A door body 2 is installed on the outer wall of the detection table 1 on one side of the second built-in cavity 12. A turntable 3 is provided inside the first built-in cavity 11. Fixed structures 4 are evenly fixed at the top of the turntable 3. The fixed structure 4 includes a fixed cylinder 401, a first return spring 402, a return plate 403, a spring piece 404, a clamping groove 405, a movable groove 406, a second return spring 407 and a clamping block 408. The fixed cylinders 401 are evenly fixed at the top of the turntable 3. The first return springs 402 are fixed at the bottom of each fixed cylinder 401. Clamping grooves 405 are evenly opened on both sides inside the fixed cylinder 401. The return plates 403 are fixed at the top of the first return springs 402. The spring pieces 404 are fixed at the top of the return plates 403. Movable grooves 406 are opened on both sides inside the return plate 403. Second return springs 407 are provided inside the movable grooves 406. Clamping blocks 408 are fixed at one end of each second return spring 407. The return plate 403 and the spring piece 404 form a telescopic structure through the first return spring 402. The clamping block 408 and the fixed cylinder 401 form a clamping structure with the clamping groove 405. The main view section of the spring piece 404 is designed in a "V" shape. The inner side of the spring piece 404 abuts against the outer side of the test tube 5. The turntable 3 and the detection table 1 form a rotating structure. The top of the turntable 3 and the top of the detection table 1 are on the same horizontal plane. The bottom end of the support 6 is fixedly connected to the inner wall of the detection table 1.

[0037] Refer to Figure 4 and Figure 5 As shown, move the test tube 5 with the reagent to be detected between the spring pieces 404 and press it downwards, so that the spring piece 404 drives the return plate 403 to move downwards. Under the action of the spring piece 404, the test tube 5 can be clamped to prevent the test tube 5 from displacing inside the fixed cylinder 401. At this time, the clamping block 408 moves into the movable groove 406. Under the elastic force of the second return spring 407, the clamping block 408 moves into the clamping groove 405, so that the return plate 403 and the fixed cylinder 401 are fixed to each other. Press the test tube 5 to separate the return plate 403 from the fixed cylinder 401. Under the elastic force of the first return spring 402, the return plate 403 drives the test tube 5 to move upwards through the spring piece 404, which is convenient for taking out the test tube 5.

[0038] Inside the fixed structure 4, there is a test tube 5. A through groove 13 runs through the inside of the turntable 3. A support 6 runs through the inside of the through groove 13. At the top of the support 6, there is a moving structure 7. The moving structure 7 includes an electric push rod 701, a tank body 702, a sealing cover 703, a movable plate 704, a fixing plate 705, an infrared sensor 706, a dropper 707, a solenoid valve 708, and a hose 709. The electric push rod 701 runs through one side of the top of the support 6. At the top of the support 6 on one side of the electric push rod 701, the tank body 702 is fixed. The outer side of the top of the tank body 702 is threadedly connected with the sealing cover 703. The bottom end of the electric push rod 701 is fixed with the movable plate 704. On one side of the movable plate 704, the fixing plate 705 is fixed. On one side of the bottom of the fixing plate 705, the infrared sensor 706 is installed. One side of the inside of the movable plate 704 runs through the dropper 707. The solenoid valve 708 is installed outside the dropper 707. On one side of the top of the dropper 707, the hose 709 is fixed. One end of the hose 709 away from the dropper 707 passes through the support 6 and is connected to one side of the bottom of the tank body 702. The hose 709 and the support 6 form a sliding structure.

[0039] Refer to Figure 6 and Figure 7 As shown, under the action of the infrared sensor 706, the fixed cylinder 401 drives the test tube 5 to move below the dropper 707. Start the electric push rod 701. The electric push rod 701 drives the movable plate 704 to move downward. The movable plate 704 drives the dropper 707 to move to the top of the test tube 5. Under the action of the solenoid valve 708, the enzyme reagent inside the tank body 702 enters the inside of the dropper 707 through the hose 709, and then enters the inside of the test tube 5 to combine with the reagent to be detected. By moving the dropper 707 to the top of the test tube 5, the contact between the enzyme reagent and the air can be reduced, so as to improve the detection accuracy.

[0040] Inside the first built-in cavity 11 on one side of the turntable 3, there is a rotating structure 9. The rotating structure 9 includes a gear 901, teeth 902, and a driving motor 903. The gear 901 is arranged inside the first built-in cavity 11 on one side of the turntable 3. The outer side of the bottom of the turntable 3 is evenly fixed with teeth 902. At the top of the second built-in cavity 12 below the gear 901, the driving motor 903 is installed. The gear 901 and the teeth 902 are meshed. The output end of the driving motor 903 extends into the inside of the first built-in cavity 11 and is fixed to the bottom end of the gear 901. On one side of the top of the detection table 1, a fixed seat 8 is fixed. On one side of the top of the fixed seat 8, a luminescence analyzer 10 is arranged.

[0041] Refer to Figure 8 and Figure 9As shown, start the drive motor 903. The drive motor 903 drives the gear 901 to rotate inside the first built-in cavity 11. The gear 901 drives the turntable 3 to rotate inside the first built-in cavity 11 through the teeth 902. The turntable 3 drives the fixed cylinder 401 to rotate, so that the fixed cylinder 401 moves below the dropper 707 and below the luminescence analyzer 10 for continuous detection. When the test tube 5 is moved below the dropper 707 to combine with the enzyme reagent, an antigen-enzyme complex is formed. This complex can catalyze the substrate to show in subsequent reactions. Move the test tube 5 added with the enzyme reagent below the luminescence analyzer 10. Under the action of the luminescence analyzer 10, the reagent to be detected and the enzyme reagent inside the test tube 5 react to produce a chemiluminescence phenomenon. The concentration of the reagent antigen inside the test tube 5 is judged by measuring the luminescence signal.

[0042] Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A hepatitis B virus surface antigen detection device, comprising a detection table (1) and a door body (2); Characterized in that: A first built-in cavity (11) is provided at the top of the detection table (1), a second built-in cavity (12) is opened inside the detection table (1) below the first built-in cavity (11), a door body (2) is installed on the outer wall of the detection table (1) on one side of the second built-in cavity (12), a turntable (3) is arranged inside the first built-in cavity (11), and fixing structures (4) are uniformly fixed at the top end of the turntable (3). The fixing structure (4) includes a fixing cylinder (401), a first return spring (402), a return plate (403), a spring piece (404), a clamping groove (405), a movable groove (406), a second return spring (407) and a clamping block (408). The fixing cylinders (401) are uniformly fixed at the top end of the turntable (3), the first return springs (402) are fixed at the bottom of the fixing cylinders (401), clamping grooves (405) are uniformly opened on both sides inside the fixing cylinders (401), the return plates (403) are fixed at the top ends of the first return springs (402), the spring pieces (404) are fixed at the top ends of the return plates (403), movable grooves (406) are opened on both sides inside the return plates (403), second return springs (407) are arranged inside the movable grooves (406), and the clamping blocks (408) are fixed at one ends of the second return springs (407). Test tubes (5) are arranged inside the fixing structures (4); A through groove (13) penetrates through the inside of the turntable (3), a support (6) penetrates through the inside of the through groove (13), and a moving structure (7) is arranged at the top of the support (6); A rotating structure (9) is arranged inside the first built-in cavity (11) on one side of the turntable (3), a fixing seat (8) is fixed at one side of the top end of the detection table (1), and a luminescence analyzer (10) is arranged at one side of the top of the fixing seat (8).

2. The hepatitis B virus surface antigen detection device according to claim 1, characterized in that: The turntable (3) and the detection table (1) form a rotating structure. The top end of the turntable (3) and the top end of the detection table (1) are on the same horizontal plane, and the bottom end of the support (6) is fixedly connected to the inner wall of the detection table (1).

3. The hepatitis B virus surface antigen detection device according to claim 1, characterized in that: The return plate (403) and the spring piece (404) form a telescopic structure through the first return spring (402), and the clamping block (408), the fixing cylinder (401) and the clamping groove (405) form a clamping structure.

4. The hepatitis B virus surface antigen detection device according to claim 1, wherein: The main view cross-section of the spring piece (404) is designed in a "V" shape, and the inner side of the spring piece (404) abuts against the outer side of the test tube (5).

5. The hepatitis B virus surface antigen detection device according to claim 1, wherein: The moving structure (7) includes an electric push rod (701), a tank body (702), a sealing cover (703), a movable plate (704), a fixing plate (705), an infrared sensor (706), a dropper (707), a solenoid valve (708) and a hose (709). The electric push rod (701) penetrates through one side of the top of the support (6), and the tank body (702) is fixed to the top end of the support (6) on one side of the electric push rod (701). The sealing cover (703) is threadedly connected to the outside of the top of the tank body (702).

6. The hepatitis B virus surface antigen detection device according to claim 5, wherein: The bottom end of the electric push rod (701) is fixed with a movable plate (704), one side of the movable plate (704) is fixed with a fixing plate (705), and an infrared sensor (706) is installed on one side of the bottom of the fixing plate (705).

7. The hepatitis B virus surface antigen detection device according to claim 5, wherein: One side of the inside of the movable plate (704) penetrates through a dropper (707), a solenoid valve (708) is installed on the outside of the dropper (707), and a hose (709) is fixed to one side of the top of the dropper (707).

8. The hepatitis B virus surface antigen detection device according to claim 7, characterized in that: One end of the hose (709) away from the dropper (707) passes through the support (6) and is communicated with one side of the bottom of the tank body (702), and the hose (709) and the support (6) form a sliding structure.

9. The hepatitis B virus surface antigen detection device according to claim 1, wherein: The rotating structure (9) includes a gear (901), teeth (902) and a driving motor (903). The gear (901) is arranged inside the first inner cavity (11) on one side of the turntable (3), teeth (902) are uniformly fixed to the outside of the bottom of the turntable (3), and the driving motor (903) is installed on the top of the second inner cavity (12) below the gear (901).

10. The hepatitis B virus surface antigen detection device according to claim 9, characterized in that: The gear (901) and the teeth (902) are meshed and connected, and the output end of the driving motor (903) extends into the inside of the first inner cavity (11) and is fixedly connected to the bottom end of the gear (901).

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