Chronic kidney disease risk early warning method and system

Abstract

The invention relates to the technical field of medical information and management, in particular to a chronic kidney disease risk early warning method and system, a management terminal, a mobile terminal, a use terminal and an external interaction terminal. Wherein the management terminal judges whether the patients have the risk of suffering from chronic kidney diseases or not according to the calculated result and performs grouping management, and first work patients engaged in work of harmful chemical substances are divided in grouping management crowds; the mobile terminal comprises a chronic kidney disease management APP; the external interaction terminal is provided with a scanning and recording module linked with the chronic kidney disease management APP, and the scanning and recording module is used for obtaining pollution data monitored by the monitoring sensor of the working environment where the first working patient is located, the use time of the personal protection equipment and the filtering efficiency through the Internet of Things, recording the data and transmitting the data to the chronic kidney disease management APP. According to the system and the method, additional groups are provided for people engaged in harmful chemical substance work, and comprehensive early warning is carried out, so that the risk of suffering from the chronic kidney disease is evaluated more accurately.

Description

Technical Field

[0001] The present invention relates to the technical field of medical information and management, and particularly relates to a method and system for early warning of chronic kidney disease risk. Background Art

[0002] Chronic kidney disease (CKD) is a disease with progressive impairment of renal function, involving chronic damage to the structure and function of the kidneys caused by various etiologies, gradually leading to renal insufficiency. The kidneys, as important detoxifying organs of the human body, are responsible for excreting metabolic products and toxins, regulating water-salt balance and acid-base balance, and synthesizing hormones and other physiological functions. However, the renal function of patients with chronic kidney disease gradually declines and cannot complete these important functions, resulting in the accumulation of waste in the body and triggering a series of serious complications. These complications include osteoporosis, disorders of water and electrolytes (such as edema, hypertension, abnormal electrolytes in the blood), anemia, and an increased risk of cardiovascular diseases. Chronic kidney disease has a high disability and fatality rate. Especially in the end stage, patients need to spend a large amount of money on dialysis or kidney transplantation, bringing huge economic and psychological burdens to themselves and their families.

[0003] In view of the serious harm of chronic kidney disease, it is particularly important to conduct early warning and intervention for it. The purpose of early warning management is to identify high-risk populations of chronic kidney disease in advance through scientific assessment means, so as to take corresponding preventive measures, delay the progression of the disease, reduce the risk of complications, and thus improve the quality of life of patients. Implementing early warning management can not only relieve the pain and economic pressure of patients, but also reduce the waste of medical resources and improve the efficiency and quality of medical services. However, the existing chronic kidney disease risk early warning technologies have certain defects. Especially among the people engaged in work with harmful chemicals, since these chemicals (such as cadmium, mercury, etc.) may cause damage to the kidneys, this group of people should be grouped separately for early warning. The reason is that the risk of chronic kidney disease in this group of people is often higher and the condition may be more complex. Traditional early warning methods often ignore the particularity of this group, resulting in poor early warning effects. Therefore, it is necessary to develop a more accurate and personalized method and system for early warning of chronic kidney disease risk to better meet the health management needs of this group of people. Summary of the Invention

[0004] To solve the above problems, the present invention provides a method and system for early warning of chronic kidney disease risk, which provides additional grouping for people engaged in work with harmful chemicals and conducts comprehensive early warning to more accurately assess their risk of chronic kidney disease.

[0005] To achieve the above object, the technical solution of the present invention is as follows: A chronic kidney disease risk warning system includes a management terminal, a mobile terminal, a usage terminal, and an external interaction terminal. The management terminal is signal-connected to the mobile terminal through the cloud, and the mobile terminal is signal-connected to the usage terminal through Bluetooth;

[0006] Among them, the management terminal is used to record the electronic medical record of the patient after physical examination and calculate the glomerular filtration rate for analysis, judge whether the patient has the risk of suffering from chronic kidney disease through the calculated result, and conduct grouped management. Among the grouped management population, there is a first working patient who is engaged in work with harmful chemicals but has not developed chronic kidney disease or has developed symptoms of chronic kidney disease. After grouped management, the management terminal customizes the early morning urine discharge time period for each patient on the day of re-examination according to the working time and waking-up time submitted in the patient's electronic medical record information; the management terminal is also used to receive the patient's self-management information situation from the mobile terminal and provide it for medical staff to view. Among them, the medical staff focuses on the change of the kidney disease risk of the first working patient through the management terminal;

[0007] The mobile terminal includes a chronic kidney disease management APP. The chronic kidney disease management APP is used to push intelligent diet and health plans to the patient in a targeted manner through the patient grouping data displayed in the grouped management when the patient conducts autonomous home management, and is also used to regularly remind the patient to urinate and send samples for inspection;

[0008] The usage terminal includes a urine protein bucket, and the urine protein bucket is used to monitor whether the patient urinates and the urination situation;

[0009] The external interaction terminal communicates according to the work unit where the first working patient grouping population is located and sets a scanning record module linked to the chronic kidney disease management APP. The scanning record module is used to scan the chronic kidney disease management APP when the first working patient punches in at work and correspondingly activate data recording. The scanning record module is also used to obtain the pollution data monitored by the monitoring sensor in the working environment where the first working patient is located, the usage time and filtration efficiency of personal protective equipment through the Internet of Things, record the data, and transmit it to the chronic kidney disease management APP.

[0010] The technical principle of the above solution is as follows:

[0011] By calculating and analyzing the patient's physical examination data and glomerular filtration rate, the management terminal can determine whether the patient has a risk of chronic kidney disease and group and manage the patients according to the risk level. In addition, the management terminal can also receive the patient's self-management information from the mobile terminal for medical staff to view and evaluate. By recommending the download of the Chronic Kidney Disease Management APP for the grouped patients, the APP can obtain the grouped data of the patients in the management terminal and provide personalized intelligent diet and health plan push based on these data. These push contents are customized based on the specific conditions and disease risks of the patients, aiming to help patients improve their lifestyles and reduce the risk of disease. In addition, the APP can regularly remind patients to urinate independently and submit samples for inspection to monitor indicators such as urinary protein in the urine, so as to further evaluate kidney function. The use terminal includes a urinary protein bucket, which is used to monitor the patient's urination situation and urinary protein content. Urinary protein is an important indicator of chronic kidney disease. By monitoring the content of urinary protein, it can be initially judged whether the patient's kidney function is damaged. The urinary protein bucket is connected to the mobile terminal through Bluetooth signals and transmits the monitoring data to the APP for patients and medical staff to view and analyze. The scanning record module activates data recording by scanning the APP when the patient punches in at work, realizing seamless docking between the APP and the working environment. The data collected (including work environment monitoring data, personal protective equipment usage data, etc.) is transmitted to the APP and integrated and analyzed with the data of the management terminal to form a more accurate risk assessment of chronic kidney disease.

[0012] The above solution has the following beneficial effects:

[0013] 1. In this solution, by recording and analyzing the patient's physical examination data in detail, especially important indicators such as glomerular filtration rate, it can more accurately determine whether the patient has a risk of chronic kidney disease. The external interaction terminal and the scanning record module set by the work unit achieve seamless docking with the Chronic Kidney Disease Management APP. Through the Internet of Things technology, the system can real-time monitor the pollution data of the patient's working environment and the usage of personal protective equipment. These data are integrated and analyzed with the patient's physical examination data, self-management information, etc., thus further improving the accuracy of risk assessment.

[0014] 2. In this solution, through the Chronic Kidney Disease Management APP, the system can provide personalized intelligent diet and health plan push for patients based on their grouped data and specific conditions. The pushed content not only considers the patient's physiological indicators but also multiple factors such as their living habits and working environment, aiming to help patients improve their lifestyles and reduce the risk of disease.

[0015] 3. In this solution, the APP regularly reminds patients to urinate independently and submit urine samples for testing, monitors indicators such as urinary protein in urine, enhances patients' self-management ability. Patients can view their own health data and risk assessment results through the APP, thereby paying more attention to their health conditions and taking active preventive measures.

[0016] 4. In this solution, the management terminal can receive patients' self-management information from mobile terminals for medical staff to view and evaluate, enabling medical staff to more comprehensively understand patients' health conditions, promptly discover problems and take intervention measures, thus improving work efficiency. Through accurate risk assessment and personalized health management, this system helps reduce unnecessary waste of medical resources. High-risk patients can receive timely attention and intervention, while low-risk patients can reduce the risk of illness through self-management, thereby achieving the rational utilization of medical resources.

[0017] Furthermore, the management terminal includes a hospital transmission and reception module, a medical record module, a calculation and analysis module, a grouping management module, a data viewing module, and a communication module;

[0018] The hospital transmission and reception module is used to download patients' data monitored by each patient's mobile terminal through the cloud, and is also used to upload the dietary conditions and health management plans required by different patients to the cloud through big data;

[0019] The medical record module is used to store patients' physical examination results and generate electronic medical records, and at the same time transmit the electronic medical records to the calculation and analysis module and the grouping management module for analysis and management of patients' individual conditions;

[0020] The calculation and analysis module is used to calculate the glomerular filtration rate through patients' physical examination data, analyze whether the obtained glomerular filtration rate is within the preset range, and transmit the data to the grouping management module; the calculation and analysis module is also used to regularly calculate the expected physical conditions of patients under the customized diet and health management according to the usage time of patients' mobile terminals, and compare and analyze the data of patients' physical conditions during multiple reexaminations. The calculation and analysis module will also comprehensively evaluate and analyze the expected physical conditions of patients based on the work data of patients in the first working patient group transmitted by the Chronic Kidney Disease Management APP;

[0021] The grouping management module is used to comprehensively compare and analyze the electronic medical records of patients in the medical record module and the glomerular filtration rate of patients in the calculation and analysis module for grouping. The grouping includes suspected patients, confirmed patients, and first working patients who are engaged in work with harmful chemicals but have not developed chronic kidney disease or have developed symptoms of chronic kidney disease. Among them, suspected patients are grouped into second working patients and non-working patients who are unemployed or self-employed;

[0022] Dynamically adjust, regroup and manage patients based on their improvement, stability and deterioration in each cycle;

[0023] The data viewing module is used by medical staff to call up data from the medical record module, calculation and analysis module, and group management module, as well as the patient self-management data transmitted by the chronic kidney management APP received by the hospital's transmission and receiving module;

[0024] The communication module is used by medical staff to respond to patients' inquiries in a timely manner and provide personalized guidance and suggestions. The communication module also supports video call function between patients and medical staff to facilitate face-to-face communication and diagnosis when necessary.

[0025] Beneficial effects: The hospital's transmission and receiving module can download the data monitored by the patient's mobile terminal in real time, and upload the dietary conditions and health management plans required by different patients, ensuring the timeliness and accuracy of the data. The calculation and analysis module analyzes the patient's renal function by calculating key indicators such as glomerular filtration rate, providing a scientific basis for group management. The group management module compares and analyzes the patient's electronic medical records and glomerular filtration rate, and divides the patients into different groups such as suspected patients, confirmed patients, and first-time patients working with harmful chemicals, realizing accurate classification of the patient's condition. The group management module also dynamically adjusts, regroups and manages according to the improvement, stability and deterioration of the patient's condition, ensuring the pertinence and effectiveness of management measures. Through precise grouping and dynamic management, the system can reasonably allocate medical resources to ensure that high-risk patients receive timely attention and intervention, while low-risk patients can reduce the risk of illness through self-management, thereby realizing the rational use of medical resources.

[0026] Furthermore, the chronic kidney management app has built-in user transmission and reception modules, recording modules, reminder modules, and feedback modules;

[0027] The user transmission and reception module is used to receive the monitoring data of the urine protein bucket and the personalized diet and health planning data of the receiving management terminal, as well as to transmit the urine volume and urination records of the patient using the urine protein bucket during the re-examination schedule; for patients grouped in the first working patient group, the user transmission and reception module is also used to scan and link with the scanning and recording module to obtain the working hours, surrounding pollutant concentrations and protective equipment wearing time of the first working patient;

[0028] The recording module is used to record the urine volume and urination data of the patient using the urine protein bucket during the re-examination schedule. The recording module is also used for the daily diet and health information recorded by the patient during daily self-management, and transmitted to the user transmission and receiving module. The recording module is also used to record the working data of the first working patient by scanning the recording module, and the harmful substance working time of the first working patient is transmitted in combination with the daily self-management information of the group of patients;

[0029] The reminder module is used to remind the patient of the re-examination time and remind the patient to urinate in the urine protein bucket on the day of the re-examination;

[0030] The feedback module is used by patients to send consultation information to medical staff and provide feedback on the use of the chronic kidney management APP.

[0031] Beneficial effects: The user transmission and receiving module can receive the monitoring data of the urine protein bucket in real time, including key information such as urine volume, urination records and urine protein content, providing patients and medical staff with timely and accurate means of disease monitoring. The recording module records in detail the urine volume and urination data of the patient using the urine protein bucket during the re-examination schedule, as well as the patient's diet and health information during daily self-management, providing patients with a complete health record. For first-time patients working with hazardous chemicals, the recording module also records their working hours and hazardous substance working hours, providing an important basis for medical staff to evaluate the impact of the working environment on the patient's condition. The reminder module can intelligently remind patients of the re-examination time, and specially remind patients to urinate in the urine protein bucket on the day of the re-examination to ensure that patients can monitor and review their condition on time. The feedback module allows patients to send consulting information to medical staff and promptly answer questions and problems encountered by patients during self-management.

[0032] Furthermore, the urine protein bucket includes a barrel body and handles hinged on both sides of the barrel body, an induction layer is provided on the inner bottom wall of the barrel body, a pressure sensor is provided in the induction layer, the pressure sensor is used to sense the weight of urine in the barrel body and the weight change signal, so as to transmit it to the recording module, an NFC card slot is opened on the outer wall of the barrel body, an NFC card for identifying patient information is placed in the NFC card slot, a transparent cover is hinged on one side of the NFC card slot, a transmission and receiving module is also provided in the NFC card slot, the transmission and receiving module is connected to the pressure sensor signal, and the transmission and receiving module is connected to the chronic kidney management APP via Bluetooth signal.

[0033] Beneficial effects: The induction layer provided on the inner bottom wall of the barrel is embedded with a pressure sensor, which can accurately sense the weight of urine in the barrel and the change signal of the weight. This function provides accurate data on the urine volume of patients for medical staff, helping to evaluate the renal function status and water balance of patients. An NFC card is placed in the NFC card slot opened on the outer side wall of the barrel for identifying the personal information of patients. This design simplifies the process of entering patient information, avoids the cumbersome and error-prone manual input, and improves the efficiency and accuracy of data processing. The combination use of the urine protein barrel and the Chronic Kidney Disease Management APP facilitates the remote communication and health management between patients and medical staff. Patients can monitor their urine at home and send the data to medical staff through the APP, realizing remote disease monitoring and health management.

[0034] A method for warning of chronic kidney disease risk, comprising the following steps:

[0035] Step 1, grouping management: Input the physical examination results of patients into the management terminal. Through the glomerular filtration rate calculated by the management terminal, the management terminal combines the electronic medical records of patients and divides them into suspected patients, confirmed patients, and first working patients who are engaged in work with harmful chemicals but have not developed chronic kidney disease or have developed symptoms of chronic kidney disease. Among them, the suspected patients are grouped into second working patients and non-working patients who are unemployed or self-employed, and corresponding management medical staff are assigned to patients in each group;

[0036] Step 2, symptom tracking and management: Assign urine protein barrels to patients of suspected patients and first working patients and register information. During the period of independent management at home by suspected patients and first working patients, they urinate into the urine protein barrel and send it for inspection regularly every month according to the schedule customized by the Chronic Kidney Disease Management APP. At the same time, they conduct self-management according to the diet plan and health knowledge customized by the Chronic Kidney Disease Management APP;

[0037] For the patients in the first working patient group, when they work, they are mutually identified by the Chronic Kidney Disease Management APP and the scanning record module. During their work, the scanning record module obtains the pollution concentration and the wearing duration of protective equipment in the working environment of the patients in the first working patient group through the Internet of Things and transmits the data to the Chronic Kidney Disease Management APP. After the Chronic Kidney Disease Management APP transmits the data to the management terminal, the calculation and analysis module will jointly calculate the glomerular filtration rate of the patients in the first working patient group in combination with their work data;

[0038] Step 3, data analysis: Obtain the home health check-in situation of patients through the management terminal, analyze the information tables of blood pressure, BMI, exercise, diet, and self-management ability, and compare and analyze and summarize the physical examination reports with the information tables when patients send samples for inspection regularly every month;

[0039] Step 4, Communication: For patients with a large difference in the analysis and summary results, the management terminal reminds the corresponding management medical staff in each group to conduct an in-person interview with the patient or communicate online through the Chronic Kidney Disease Management APP to solve the problems of independent management existing in the patient; and for patients who exceed the inspection schedule reminder of the Chronic Kidney Disease Management APP by 15 days, the management terminal classifies such patients into the list of missed inspections, and the management medical staff in the corresponding group will contact them to understand the reasons for the patient's non-return visit.

[0040] Further, in Step 1, the patient data recorded in the physical examination are: age, work situation, height, weight, BMI, urinary protein, serum creatinine, serum albumin, and blood uric acid.

[0041] Further, in Step 1, the physical examination results are based on the evaluation of the patient's urinary protein, glomerular filtration rate, serum creatinine, serum albumin, and blood uric acid. Among them, the calculation formula for the glomerular filtration rate is:

[0042] GFR = 144×(serum creatinine (mg / dl) / 0.7) -0.329 ×(0.993) 年龄 (when female serum creatinine ≤ 0.7mg / dl);

[0043] GFR = 144×(serum creatinine (mg / dl) / 0.7) -1.209 ×(0.993) 年龄 (when female serum creatinine > 0.7mg / dl);

[0044] GFR = 141×(serum creatinine (mg / dl) / 0.9) -0.411 ×(0.993) 年龄 (when male serum creatinine ≤ 0.9mg / dl);

[0045] GFR = 141×(serum creatinine (mg / dl) / 0.9) -1.209 ×(0.993) 年龄 (when male serum creatinine > 0.9mg / dl);

[0046] Among them, the unit conversion of serum creatinine is 1mg / dl = 88.4μmol / L.

[0047] Further, in Step 2, for the urination schedule that needs to be sent for inspection of the second working patients among the first working patients and suspected patients, according to the working time information and wake-up time submitted by the patients in the electronic medical record, monitor whether they urinate within 4 hours after their wake-up time. If they urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP for time recording. If they do not urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP to remind the working patients once an hour. For situations exceeding the time period, the Chronic Kidney Disease Management APP will remind the patients to urinate and then send for inspection within the designated time period the next day.

[0048] Further, in Step 2, for the urination schedule that needs to be sent for inspection of the non-working patients among the suspected patients, the Chronic Kidney Disease Management APP will remind the non-working patients to urinate from 5:00 am to 11:00 am on the day of inspection by means of push notification one day before the inspection schedule, and monitor through the urine protein bucket within this time period on the day of inspection. If they urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP for time recording. If they do not urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP to remind the working patients once an hour. For situations exceeding the time period, the Chronic Kidney Disease Management APP will remind the patients to urinate and then send for inspection within the designated time period the next day.

[0049] Further, in Step 2, for the first working patients, the Chronic Kidney Disease Management APP records the daily working hours of the first working patients with a cycle of 7 days and transmits them to the management terminal. When rechecking the first working patients, comprehensively consider the physical examination results, self-management situation, and working hours. After the management terminal predicts and judges their conditions, it is convenient for medical staff to communicate with the first working patients.

[0050] Beneficial effects: 1. In this solution, by inputting the physical examination results of the patients into the management terminal, combining the glomerular filtration rate and the electronic medical record, the patients are accurately classified into groups such as suspected patients, confirmed patients, and the first working patients engaged in harmful chemical substances work. This grouped management helps to formulate personalized management strategies for patients with different conditions and risk factors, improving the pertinence and effectiveness of management.

[0051] 2. In this solution, urine protein buckets are allocated to suspected patients and the first working patients, and relevant information is registered. The patients conduct urine monitoring and send for inspection at home according to the schedule customized by the Chronic Kidney Disease Management APP, and at the same time conduct self-management following the diet plan and health knowledge provided by the APP. This intelligent symptom tracking method not only improves the patients' participation but also ensures the accuracy and timeliness of the data.

[0052] 3. In this solution, the management terminal can obtain the home health check-in status of patients and analyze the information sheets of blood pressure, BMI, exercise, diet, and self-management ability. By comparing and analyzing these information with the patients' physical examination reports, medical staff can more comprehensively understand the patients' health status and disease changes, providing a basis for subsequent management and intervention.

[0053] 4. In this solution, for patients in different groups, the method of the present invention provides personalized management strategies. For example, for the first working patients and the second working patients, different urine monitoring time periods are set according to different situations on weekdays and rest days; for non-working patients, reminders are pushed through the APP to ensure that they conduct urine monitoring within the specified time. In addition, for the first working patients who are long-term exposed to harmful chemicals, reminders for recording working hours are additionally set to comprehensively consider their condition and work situation.

[0054] Additional aspects and advantages of the present invention will be given in part in the following description, become apparent in part from the following description, or be understood through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0055] Figure 1 It is a schematic diagram of the system framework of an embodiment of the method and system for early warning of chronic kidney disease risk of the present invention;

[0056] Figure 2 It is a schematic diagram of the method steps of an embodiment of the method and system for early warning of chronic kidney disease risk of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0057] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. Apparently, the described embodiments are some, but not all, of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0058] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0059] In the description of the present invention, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection", and "coupling" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0060] The following is a further detailed description through specific embodiments:

[0061] Embodiment 1:

[0062] As shown in the Figure 1 accompanying drawings: A chronic kidney disease risk warning system includes a management terminal, a mobile terminal, and a user terminal. The management terminal is connected to the mobile terminal through a cloud signal, and the mobile terminal is connected to the user terminal through a Bluetooth signal.

[0063] Among them, the management terminal is used to record the electronic medical records of patients after physical examinations and calculate the glomerular filtration rate for analysis, and determine whether the patients have the risk of suffering from chronic kidney disease and conduct grouped management based on the calculated results. Among the grouped management population, there is a first working patient who is engaged in work with harmful chemicals but has not developed chronic kidney disease or has developed symptoms of chronic kidney disease. After grouped management, the management terminal customizes the early morning urine discharge time period for each patient on the day of reexamination according to the working time and waking time submitted in the patient's electronic medical record information; the management terminal is also used to receive the patient self-management information situation of the mobile terminal and provide it for medical staff to view. Among them, the medical staff focuses on the change of the kidney disease risk of the first working patient through the management terminal. The management terminal includes a hospital transmission and reception module, a medical record module, a calculation and analysis module, a grouped management module, a data viewing module, and a communication module.

[0064] The hospital transmission and reception module is used to download the patient data monitored by each patient's mobile terminal through the cloud, and the hospital transmission and reception module is also used to upload the diet situation and health management plan required by different patients to the cloud through big data;

[0065] The medical record module is used to store the physical examination results of patients and generate electronic medical records, and at the same time transmit the electronic medical records to the calculation and analysis module and the grouped management module for patient individual situation analysis and management;

[0066] The calculation and analysis module is used to calculate the glomerular filtration rate through the patient's physical examination data, analyze whether the obtained glomerular filtration rate is within the preset range, and transmit the data to the grouping management module; the calculation and analysis module is also used to regularly calculate the patient's predicted physical condition under the customized diet and health management according to the usage time of the patient's mobile terminal, and compare and analyze the data of the patient's physical condition during multiple reexaminations. The calculation and analysis module will also comprehensively evaluate and analyze the patient's predicted physical condition based on the patient work data of the first working patient group transmitted by the chronic kidney disease management APP;

[0067] The grouping management module is used to compare and analyze the electronic medical records of the patient in the comprehensive medical record module and the glomerular filtration rate of the patient in the calculation and analysis module for grouping. The grouping includes suspected patients, diagnosed patients, and the first working patients who are engaged in work with harmful chemicals but have not developed chronic kidney disease or have developed symptoms of chronic kidney disease. Among them, the suspected patients are grouped into the second working patients and non-working patients who are unemployed or self-employed;

[0068] For the improvement, stability, and deterioration of the patient's condition within each cycle, dynamic adjustment is carried out, and grouping and management are re-performed; among them, the improvement of the patient is defined as a series of improvements in renal function indicators such as a decrease in serum creatinine level, an increase in glomerular filtration rate, a decrease in urinary protein quantification, and an increase in urine volume compared with the initial examination. The stability of the patient is defined as a series of stable pathological indicators such as small fluctuations in serum creatinine level, urine volume remaining consistent with the initial examination, glomerular filtration rate maintaining within the preset constant range, and no significant increase in urinary protein quantification. The deterioration of the patient is defined as a series of deteriorations in pathological indicators such as an increase in serum creatinine level, a decrease in urine volume compared with the initial examination, a decrease in glomerular filtration rate, and a significant increase in urinary protein quantification;

[0069] The data viewing module is used for medical staff to call the data of the medical record module, the calculation and analysis module, and the grouping management module, as well as the patient self-management data transmitted by the chronic kidney management APP received by the hospital transmission and reception module;

[0070] The communication module is used for medical staff to promptly reply to the patient's consultations through the communication module and provide personalized guidance and suggestions. The communication module also supports the video call function between the patient and the medical staff for face-to-face communication and diagnosis when necessary.

[0071] The mobile terminal includes the chronic kidney disease management APP. The chronic kidney disease management APP is used to, based on the patient grouping data displayed in the grouping management, push intelligent diet and health plans to the patient in a targeted manner through the data of the management terminal when the patient conducts autonomous home management, and is also used to regularly remind the patient to urinate and submit samples independently. The chronic kidney management APP is built-in with a user transmission and reception module, a recording module, a reminder module, and a feedback module;

[0072] The user transmission and reception module is used to receive the monitoring data of the urine protein bucket and the personalized diet and health planning data of the receiving management terminal, as well as to transmit the urine volume and urination records of the patient using the urine protein bucket during the re-examination schedule; for patients grouped in the first working patient group, the user transmission and reception module is also used to scan and link with the scanning and recording module to obtain the working hours, surrounding pollutant concentrations and protective equipment wearing time of the first working patient;

[0073] The recording module is used to record the urine volume and urination data of the patient using the urine protein bucket during the re-examination schedule. The recording module is also used for the daily diet and health information recorded by the patient during daily self-management, and transmitted to the user transmission and receiving module. The recording module is also used to record the working data of the first working patient by scanning the recording module, and the harmful substance working time of the first working patient is transmitted in combination with the daily self-management information of the group of patients;

[0074] The reminder module is used to remind the patient of the re-examination time and remind the patient to urinate in the urine protein bucket on the day of the re-examination;

[0075] The feedback module is used by patients to send consultation information to medical staff and provide feedback on the use of the chronic kidney management APP.

[0076] The terminal includes a urine protein bucket, which is used to monitor whether the patient urinates and the urination situation. The urine protein bucket includes a barrel body and handles hinged on both sides of the barrel body. The inner bottom wall of the barrel body is provided with a sensing layer, and the sensing layer is provided with a pressure sensor. The pressure sensor is used to sense the weight of urine in the barrel body and the weight change signal to transmit to the recording module. An NFC card slot is opened on the outer wall of the barrel body, and an NFC card for identifying patient information is placed in the NFC card slot. A transparent cover is hinged on one side of the NFC card slot. A transmission and receiving module is also provided in the NFC card slot. The transmission and receiving module is connected to the pressure sensor signal, and the transmission and receiving module is connected to the chronic kidney management APP through Bluetooth signals.

[0077] The external interactive terminal communicates according to the work unit of the first working patient group and sets up a scanning and recording module that is linked to the chronic kidney disease management APP. The scanning and recording module is used to scan the chronic kidney disease management APP when the first working patient clocks in at work and activates data records accordingly. The scanning and recording module is also used to obtain pollution data monitored by monitoring sensors of the working environment of the first working patient through the Internet of Things, as well as the usage time and filtration efficiency of personal protective equipment, and record the data and transmit it to the chronic kidney disease management APP.

[0078] The specific implementation process is as follows: By setting key parameters such as the preset range of glomerular filtration rate, the determination criteria for patient improvement, stability, and deterioration in the calculation and analysis module of the management terminal. When the physical examination results of the patient are issued as an electronic medical record through the medical record module and scanned into the NFC card, the patient downloads and installs the Chronic Kidney Disease Management APP on their personal mobile device. The patient receives a urine protein bucket, retrieves their corresponding NFC card and places it in the NFC card slot. The medical staff assigns a group to the patient through the management terminal, and the patient automatically obtains their group information by scanning the NFC card information through the APP.

[0079] For secondary working patients and non-working patients, the patient conducts daily diet and health management according to the intelligent diet and health plan pushed in the APP, records diet and health information every day, and uploads it through the APP. Before the re-examination schedule, the APP will remind the patient to urinate using the urine protein bucket within the specified time period. After urination, the APP receives the urine weight data transmitted by the urine protein bucket through Bluetooth and records the urination situation. The patient needs to send the urine sample to the designated testing institution for testing according to the reminder of the APP; for non-working patients, due to more flexible time, the patient can choose to urinate and send the sample at any time period reminded by the APP. After the re-examination, the medical staff views the patient's physical examination report and self-management data through the management terminal. According to the patient's condition changes, the medical staff will communicate with the patient through the APP or by phone to provide personalized guidance and suggestions.

[0080] For primary working patients, in addition to the ordinary diet and health plan, since primary working patients are exposed to a toxic substance environment for a long time and continuously, such as volatile organic compound concentration and heavy metal dust, the APP will also specifically remind the patient to record the daily working hours and harmful substance exposure situation. The patient needs to record these information in detail and upload it to the calculation and analysis module through the APP. The calculation and analysis module simulates the metabolic pathway of chemical substances in the body based on substance kinetics, such as the cumulative effect of cadmium in the renal tubules. When calculating the glomerular filtration rate, the calculation and analysis module combines the patient's work data, individual physiological parameters, and calculates the cumulative exposure dose to generate the toxicity load index of the primary working patient.

[0081] Due to being engaged in work with harmful chemical substances, the patient's kidney health may face higher risks. Therefore, the APP will provide the patient with more frequent urination reminders and testing arrangements. The patient needs to send the urine sample to the designated testing institution for testing regularly according to the special reminder of the APP. After the re-examination, the medical staff will pay more attention to the patient's condition changes, especially the indicators related to harmful substance exposure. According to the specific situation of the patient, the medical staff will provide more personalized guidance and suggestions, and arrange more frequent re-examinations if necessary.

[0082] Example 2:

[0083] As shown in the appendix Figure 1 and Figure 2 shown, the difference from Example 1 lies in a method for warning of chronic kidney disease risk, which is characterized by including the following steps:

[0084] Step 1, grouping management: Input the physical examination results of the patient into the management terminal. The patient data recorded in the physical examination are: age, work situation, height, weight, BMI, urinary protein, serum creatinine, serum albumin, and blood uric acid.

[0085] The glomerular filtration rate calculated by the management terminal uses the physical examination results to evaluate the patient's urinary protein, glomerular filtration rate, serum creatinine, serum albumin, and blood uric acid. Among them, the calculation formula for the glomerular filtration rate is:

[0086] GFR = 144×(serum creatinine (mg / dl) / 0.7) -0.329 ×(0.993) 年龄 (when female serum creatinine ≤ 0.7mg / dl);

[0087] GFR = 144×(serum creatinine (mg / dl) / 0.7) -1.209 ×(0.993) 年龄 (when female serum creatinine > 0.7mg / dl);

[0088] GFR = 141×(serum creatinine (mg / dl) / 0.9) -0.411 ×(0.993) 年龄 (when male serum creatinine ≤ 0.9mg / dl);

[0089] GFR = 141×(serum creatinine (mg / dl) / 0.9) -1.209 ×(0.993) 年龄 (when male serum creatinine > 0.9mg / dl);

[0090] Among them, the unit conversion of serum creatinine is 1mg / dl = 88.4μmol / L.

[0091] The management terminal combines the electronic medical records of the patients and divides them into suspected patients, confirmed patients, and first - job patients who are engaged in harmful chemical substances work but have not developed chronic kidney disease or have developed symptoms of chronic kidney disease. Among them, the suspected patients are grouped into second - job patients and non - working patients who are unemployed or self - employed, and corresponding management medical staff are assigned to the patients in each group;

[0092] Step 2, Symptom Tracking and Management: Assign urine protein buckets to patients with suspected diseases and first-job patients and register information. During the period of self-management at home for patients with suspected diseases and first-job patients, they urinate into the urine protein buckets regularly every month according to the schedule customized by the Chronic Kidney Disease Management APP and send the samples for inspection. At the same time, they conduct self-management according to the diet plan and health knowledge customized by the Chronic Kidney Disease Management APP.

[0093] For patients in the first-job patient group, when they are at work, they are mutually identified through the Chronic Kidney Disease Management APP and the scanning record module. During their work, the scanning record module obtains the pollution concentration and the wearing duration of protective equipment in the working environment of the patients in the first-job patient group through the Internet of Things and transmits the data to the Chronic Kidney Disease Management APP. After the Chronic Kidney Disease Management APP transmits the data to the management terminal, the calculation and analysis module will jointly calculate the glomerular filtration rate of the patients in the first-job patient group by combining their work data.

[0094] In the urine excretion schedule that needs to be sent for inspection for second-job patients who are first-job patients and suspected patients, according to the work time information and wake-up time submitted by the patients in their electronic medical records, monitor whether they urinate within 4 hours after their wake-up time. If they urinate, the urine protein bucket transmits a signal to the Chronic Kidney Disease Management APP for time recording. If they do not urinate, the urine protein bucket transmits a signal to the Chronic Kidney Disease Management APP to remind the working patients once an hour. For situations exceeding the time period, the Chronic Kidney Disease Management APP will remind the patients to urinate and send the sample for inspection within the specified time period the next day.

[0095] In the urine excretion schedule that needs to be sent for inspection for non-working patients with suspected diseases, the Chronic Kidney Disease Management APP will remind the non-working patients to urinate from 5:00 am to 11:00 am on the day of inspection by means of push notification one day before the inspection schedule, and monitor them through the urine protein bucket during this time period on the day of inspection. If they urinate, the urine protein bucket transmits a signal to the Chronic Kidney Disease Management APP for time recording. If they do not urinate, the urine protein bucket transmits a signal to the Chronic Kidney Disease Management APP to remind the working patients once an hour. For situations exceeding the time period, the Chronic Kidney Disease Management APP will remind the patients to urinate and send the sample for inspection within the specified time period the next day.

[0096] For first-job patients, the Chronic Kidney Disease Management APP records the daily working hours of first-job patients in a cycle of 7 days and transmits them to the management terminal. When rechecking first-job patients, the physical examination results, self-management situation, and working hours are comprehensively considered. After the management terminal predicts and judges their conditions, it is convenient for medical staff to communicate with first-job patients.

[0097] Step 3, data analysis: Obtain the patient's home health check-in situation through the management terminal, analyze the information sheets of blood pressure, BMI, exercise, diet, and self-management ability, and compare and analyze the physical examination reports with the information sheets when the patient submits samples for inspection regularly every month;

[0098] Step 4, communication: For patients with large differences in the analysis results, remind the corresponding management medical staff of each group through the management terminal to conduct face-to-face interviews with the patient or communicate online through the Chronic Kidney Disease Management APP to solve the patient's self-management problems; and for patients who exceed the inspection schedule reminder of the Chronic Kidney Disease Management APP by 15 days, the management terminal will classify such patients into the list of missed inspections, and the management medical staff of the corresponding group will contact them to understand the reasons for the patient's failure to return for a follow-up visit.

[0099] Obviously, the above embodiments are merely examples given for clear illustration and are not limitations on the implementation manners. For those of ordinary skill in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation manners here. The obvious changes or modifications derived therefrom are still within the protection scope of the present invention.

Claims

1. A chronic kidney disease risk warning system, characterized in that, It includes a management terminal, a mobile terminal, a usage terminal and an external interaction terminal. The management terminal is connected to the mobile terminal through cloud signals, and the mobile terminal is connected to the usage terminal through Bluetooth signals; Among them, the management terminal is used to record the electronic medical records of patients after physical examinations and calculate the glomerular filtration rate for analysis, and judge whether the patient has the risk of suffering from chronic kidney disease and conduct grouped management based on the calculated results. Among the grouped management population, there is a first working patient group who is engaged in work involving harmful chemicals but has not developed chronic kidney disease or has developed symptoms of chronic kidney disease. After grouped management, the management terminal customizes the morning urine discharge time period for each patient on the day of reexamination according to the working hours and wake-up time submitted in the patient's electronic medical record information; the management terminal is also used to receive the patient self-management information situation of the mobile terminal and provide it for medical staff to view. Among them, medical staff focus on the changes in the kidney disease risk of the first working patient group through the management terminal; The mobile terminal includes a chronic kidney disease management APP. The chronic kidney disease management APP is used to push intelligent diet and health plans to patients in a targeted manner through the patient grouping data displayed in the grouped management when the patients conduct autonomous home management, and is also used to regularly remind patients to urinate and send samples for inspection; The usage terminal includes a urine protein bucket, which is used to monitor whether the patient urinates and the urination situation; The external interaction terminal communicates according to the work units of the first working patient group and sets a scanning record module linked to the chronic kidney disease management APP. The scanning record module is used to scan the chronic kidney disease management APP when the first working patient punches in at work and activate the data record correspondingly. The scanning record module is also used to obtain the pollution data monitored by the monitoring sensors in the working environment of the first working patient and the usage time and filtration efficiency of personal protective equipment through the Internet of Things for data recording and transmission to the chronic kidney disease management APP.

2. The chronic kidney disease risk warning system according to claim 1, characterized in that The management terminal includes a hospital transmission and reception module, a medical record module, a calculation and analysis module, a grouped management module, a data viewing module and a communication module; The hospital transmission and reception module is used to download the patient data monitored by each patient's mobile terminal through the cloud, and the hospital transmission and reception module is also used to upload the diet situation and health management plans required by different patients to the cloud through big data; The medical record module is used to store the physical examination results of patients and generate electronic medical records, and at the same time transmit the electronic medical records to the calculation and analysis module and the grouped management module for analysis and management of the individual situation of patients; The calculation and analysis module is used to calculate the glomerular filtration rate through the patient's physical examination data, analyze whether the obtained glomerular filtration rate is within the preset range, and transmit the data to the grouped management module; The calculation and analysis module is also used to regularly calculate the expected physical condition of patients under the customized diet and health management according to the usage time of the patient's mobile terminal, and compare and analyze the data of the patient's physical condition during multiple reexaminations. The calculation and analysis module will also comprehensively evaluate and analyze the expected physical condition of patients based on the patient work data of the first working patient group transmitted by the chronic kidney disease management APP; The group management module is used to compare and analyze the electronic medical records of patients in the comprehensive medical record module and the glomerular filtration rate of patients in the calculation and analysis module to form groups, including suspected patients, confirmed patients, and first-working patients who work with harmful chemicals but do not have chronic kidney disease or have symptoms of chronic kidney disease. Suspected patients are grouped into second-working patients and unemployed or self-employed non-working patients; Dynamically adjust, regroup and manage patients based on their improvement, stability and deterioration in each cycle; The data viewing module is used by medical staff to call up data from the medical record module, calculation and analysis module, and group management module, as well as the patient self-management data transmitted by the chronic kidney management APP received by the hospital's transmission and receiving module; The communication module is used by medical staff to respond to patients' inquiries in a timely manner and provide personalized guidance and suggestions. The communication module also supports video call function between patients and medical staff to facilitate face-to-face communication and diagnosis when necessary.

3. The chronic kidney disease risk warning system according to claim 2, wherein The chronic kidney management APP has built-in user transmission and reception modules, recording modules, reminder modules and feedback modules; The user transmission and reception module is used to receive the monitoring data of the urine protein bucket and the personalized diet and health planning data of the receiving management terminal, as well as to transmit the urine volume and urination records of the patient using the urine protein bucket during the re-examination schedule; for patients grouped in the first working patient group, the user transmission and reception module is also used to scan and link with the scanning and recording module to obtain the working hours, surrounding pollutant concentrations and protective equipment wearing time of the first working patient; The recording module is used to record the urine volume and urination data of the patient using the urine protein bucket during the re-examination schedule. The recording module is also used for the daily diet and health information recorded by the patient during daily self-management, and transmitted to the user transmission and receiving module. The recording module is also used to record the working data of the first working patient by scanning the recording module, and the harmful substance working time of the first working patient is transmitted in combination with the daily self-management information of the group of patients; The reminder module is used to remind the patient of the re-examination time and remind the patient to urinate in the urine protein bucket on the day of the re-examination; The feedback module is used by patients to send consultation information to medical staff and provide feedback on the use of the chronic kidney management APP.

4. The chronic kidney disease risk warning system according to claim 3, characterized in that, The urine protein bucket includes a bucket body and handles hinged on both sides of the bucket body. The inner bottom wall of the barrel body is provided with a sensing layer, and a pressure sensor is provided in the sensing layer. The pressure sensor is used to sense the weight of urine in the barrel body and the weight change signal to transmit it to the recording module. An NFC card slot is opened on the outer wall of the barrel body, and an NFC card for identifying patient information is placed in the NFC card slot. A transparent cover is hinged on one side of the NFC card slot. A transmission and receiving module is also provided in the NFC card slot. The transmission and receiving module is connected to the pressure sensor signal, and the transmission and receiving module is connected to the chronic kidney management APP via Bluetooth signals.

5. A method for warning of the risk of chronic kidney disease, characterized in that, The following steps are involved: Step 1, Group Management: Input the physical examination results of patients into the management terminal. Based on the glomerular filtration rate calculated by the management terminal and combined with the patients' electronic medical records, the management terminal divides the patients into suspected patients, confirmed patients, and first - working patients who are engaged in work involving harmful chemicals but have not developed chronic kidney disease or show symptoms of chronic kidney disease. Among them, the suspected patients are grouped into second - working patients and non - working patients who are unemployed or self - employed, and corresponding management medical staff are assigned to patients in each group; Step 2, Symptom Tracking and Management: Assign urine protein buckets to patients in the suspected patient group and the first - working patient group and register information. During the period of self - management at home, patients in the suspected patient group and the first - working patient group urinate into the urine protein buckets regularly every month according to the schedule customized by the Chronic Kidney Disease Management APP and send the samples for inspection. At the same time, they conduct self - management according to the diet plan and health knowledge customized by the Chronic Kidney Disease Management APP; For patients in the first - working patient group, during their work, they are mutually recognized by the Chronic Kidney Disease Management APP and the scanning record module. During their work, the scanning record module obtains the pollution concentration in the working environment of patients in the first - working patient group and the wearing duration of protective equipment through the Internet of Things and transmits the data to the Chronic Kidney Disease Management APP. After the Chronic Kidney Disease Management APP transmits the data to the management terminal, when calculating the glomerular filtration rate of patients in the first - working patient group, the calculation and analysis module will calculate in combination with their work data; Step 3, Data Analysis: Obtain the home health check - in situation of patients through the management terminal, analyze the information tables of blood pressure, BMI, exercise, diet, and self - management ability, and compare and analyze the summary of the physical examination reports with the information tables when patients send samples for inspection regularly every month; Step 4, Communication: For patients with large differences in the analysis and summary results, the management terminal reminds the management medical staff corresponding to each group to conduct face - to - face interviews with the patients or communicate online through the Chronic Kidney Disease Management APP to solve the problems of self - management existing in the patients; and for patients who exceed the inspection schedule reminder of the Chronic Kidney Disease Management APP by 15 days, the management terminal classifies such patients into the list of missed inspections, and the management medical staff corresponding to the corresponding group will contact them to understand the reasons for the patients' failure to return for re - examination.

6. The chronic kidney disease risk warning method according to claim 5, wherein In Step 1, the patient data recorded in the physical examination are: age, work situation, height, weight, BMI, urine protein, serum creatinine, serum albumin, and blood uric acid.

7. The chronic kidney disease risk warning method according to claim 6, characterized in that, In Step 1, the physical examination results are based on the evaluation of urine protein, glomerular filtration rate, serum creatinine, serum albumin, and blood uric acid. Among them, the calculation formula for the glomerular filtration rate is: GFR = 144 × (serum creatinine (mg / dl) / 0.7) -0.329 × (0.993) 年龄 (when serum creatinine in females ≤ 0.7 mg / dl); GFR = 144 × (serum creatinine (mg / dl) / 0.7) -1.209 × (0.993) 年龄 (when serum creatinine in female > 0.7 mg / dl); GFR = 141 × (serum creatinine (mg / dl) / 0.9) -0.411 × (0.993) 年龄 (when serum creatinine in males ≤ 0.9 mg / dl); GFR = 141 × (serum creatinine (mg / dl) / 0.9) -1.209 × (0.993) 年龄 (when serum creatinine in men > 0.9 mg / dl); Among them, the unit conversion of serum creatinine is 1mg / dl = 88.4μmol / L.

8. The chronic kidney disease risk warning method according to claim 7, wherein In Step 2, for the urination schedule that needs to be sent for inspection of the second working patients among the first working patients and suspected patients, according to the working time information and wake-up time submitted by the patients in the electronic medical record, monitor whether they urinate within 4 hours after their wake-up time. If they urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP for time recording. If they do not urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP to remind the working patients once an hour. For situations beyond the time period, the Chronic Kidney Disease Management APP will remind the patients to urinate and then send for inspection within the designated time period the next day.

9. The chronic kidney disease risk warning method according to claim 8, wherein In Step 2, for the urination schedule that needs to be sent for inspection of the non-working patients among the suspected patients, the Chronic Kidney Disease Management APP will remind the non-working patients to urinate from 5:00 am to 11:00 am on the day of inspection by means of push reminder one day before the inspection schedule, and monitor through the urine protein bucket within this time period on the day of inspection. If they urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP for time recording. If they do not urinate, transmit a signal through the urine protein bucket to the Chronic Kidney Disease Management APP to remind the working patients once an hour. For situations beyond the time period, the Chronic Kidney Disease Management APP will remind the patients to urinate and then send for inspection within the designated time period the next day.

10. The chronic kidney disease risk warning method according to claim 9, characterized in that In Step 2, for the first working patients, the Chronic Kidney Disease Management APP records the daily working hours of the first working patients with a cycle of 7 days and transmits them to the management terminal. When re-inspecting the first working patients, comprehensively consider the physical examination results, self-management situation, and working hours. After the management terminal predicts and judges their conditions, it is convenient for medical staff to communicate with the first working patients.

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