Weeding composition and preparation method thereof

Abstract

The present disclosure relates to an agrochemical composition, and in particular, to a herbicidal composition comprising an aniline based herbicide and a pyrimidinylsulfonylurea based herbicide. The disclosure also relates to a method for preparing the herbicidal composition and a method for controlling weeds using the herbicidal composition.

Description

Technical Field

[0001] The present disclosure relates to an agrochemical composition, and in particular, to a herbicidal composition comprising a PS II photosynthesis inhibitor herbicide and an acetolactate synthase inhibitor herbicide. More particularly, the present disclosure relates to a herbicidal composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide. The present disclosure also relates to a method for preparing the herbicidal composition and a method for using the herbicidal composition to control weeds. Background Art

[0002] Herbicides are chemicals specifically used to control weeds. The mode of action of herbicides is a biochemical or physical mechanism that is used to control unwanted plants or weeds. Most herbicides control unwanted plants or weeds by disrupting or altering one or more metabolic processes of the plants. However, there are certain unwanted plant / weed species or groups of unwanted plant / weed species that are insensitive to certain herbicides. This may be because the herbicides use different biochemical pathways or the herbicides have slightly different enzymes. Therefore, herbicides are usually selected for use based on their mode of action.

[0003] In addition, compositions containing herbicides have been used for weed control for decades. However, they still have some drawbacks. These compositions do not have any herbicidal activity / sufficient herbicidal activity against specific harmful / unwanted plants, the range of harmful / unwanted plants that can be controlled by the herbicide is not wide enough, the selectivity and compatibility of the herbicide with the crop are too low, resulting in unnecessary damage and / or an unnecessary reduction in the crop harvest yield, the initial herbicidal activity is unacceptable or not strong enough and / or the duration of the herbicidal activity is not long enough. For these reasons, there is a continuous need to develop herbicidal compositions that overcome the above drawbacks.

[0004] The use of herbicidal combinations is a widespread and well-documented practice in the agricultural field. Herbicidal combinations offer significant advantages over single applications, including improved and extended weed control, reduced herbicide application rates and costs, shorter exposure times for improved effects, reduced strict use restrictions, increased selectivity, a wider range of weed control, and reduced residual problems. However, in such combinations, the selection of the inert ingredients is crucial because, very often, adding one active ingredient to a composition of another single active ingredient further exacerbates the stability problems.

[0005] Propanil is an aniline herbicide with the chemical name 3',4'-dichloropropionanilide, and it is a widely used contact herbicide. However, in addition to having a relatively low melting point, propanil is prone to hydrolysis. If the energy input during the formation of the aqueous paste is too high, the formation of this paste may make it more difficult to achieve stability during processing. Therefore, there are several limitations on the inactive ingredients that can be used to prepare propanil granules.

[0006] Pyrazosulfuron-ethyl is a pyrimidinylsulfonylurea herbicide with the chemical name 1-(2-chloro-6-propylimidazo[1,2-b]pyridazin-3-ylsulfonyl)-3-(4,6-dimethoxypyrimidin-2-yl)urea. Pyrazosulfuron-ethyl is used as a rice herbicide to control annual and perennial paddy weeds, including Echinochloa, Cyperus, and broadleaf weeds. Pyrazosulfuron-ethyl shows characteristics that are safer for human health and the environment.

[0007] Patent application CN106489972A discloses a herbicidal composition containing pyrazosulfuron-ethyl and propanil in a weight ratio of 1:1 to 1:100 as active ingredients. This composition may also contain an agrochemical active compound (pyrazosulfuron-ethyl). In addition, this application does not disclose aspects related to improving the stability and suspension of the composition containing propanil and pyrazosulfuron-ethyl.

[0008] PCT publication WO2016116797A1 discloses a composition containing modified crystalline propanil and at least one other insecticide (pyrazosulfuron-ethyl). However, this publication does not disclose aspects related to improving the stability and suspension of the composition.

[0009] The inventors of the present disclosure have found that known compositions containing a combination of propanil and pyrazosulfuron-ethyl have poor suspension, and generally cannot pass the wet sieve test, and the shelf life of these compositions is short. These products show a considerable amount of precipitation over time, usually forming hard rock-like lumps at the bottom of the storage container. The increase in precipitation further exacerbates the problem of nozzle blockage during spraying application by farmers. Therefore, it has been found that when such compositions are prepared as diluted liquids or solutions for spraying, due to the relatively high insoluble content, after a certain period of time, the composition loses its sprayability. This sometimes leads to farmers rejecting otherwise useful products, which is undoubtedly undesirable.

[0010] Therefore, there is still a need to develop a stable herbicidal composition containing propanil and pyrazosulfuron-ethyl (preferably in the free acid form) to address the above challenges and also not affect the efficacy associated with the herbicidal composition.

[0011] The object of the present disclosure

[0012] The main object of the present disclosure is to provide a stable agrochemical composition, preferably a herbicidal composition.

[0013] Another object of the present disclosure is to provide an agrochemical composition comprising a PS II photosynthesis inhibitor herbicide and an acetolactate synthase inhibitor herbicide.

[0014] Another object of the present disclosure is to provide an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0015] Another object of the present disclosure is to provide an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersant.

[0016] Another object of the present disclosure is to provide a method for preparing an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0017] Another object of the present disclosure is to provide a method for controlling weeds using an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide. SUMMARY OF THE INVENTION

[0018] In one aspect, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0019] In another aspect, the present disclosure provides a method for preparing an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0020] In another aspect, the present disclosure provides a method for controlling weeds, the method comprising applying to the plant or its locus an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide. DETAILED DESCRIPTION OF THE INVENTION

[0022] The present disclosure will now be described below with reference to examples, in which embodiments of the present disclosure are shown. This description is not intended to be a detailed catalog of all the different ways in which the present disclosure can be implemented or all the features that can be added to the present disclosure. For example, features shown with respect to one embodiment can be incorporated into other embodiments, and features shown with respect to a particular embodiment can be deleted from that embodiment. Thus, the present disclosure contemplates that in some embodiments of the present disclosure, any feature or combination of features set forth herein can be excluded or omitted. Additionally, many variations and additions to the various embodiments proposed herein will be apparent to those skilled in the art in accordance with the present disclosure, and these variations and additions do not depart from the present disclosure. Accordingly, the following description is intended to illustrate some particular embodiments of the present disclosure, rather than to exhaustively specify all of its permutations, combinations, and variations.

[0023] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present disclosure belongs. Although methods and materials similar or equivalent to those described herein can also be used in the practice or testing of the present disclosure, suitable methods and materials are described herein.

[0024] As used herein, "about" or "approximately" is inclusive of the stated value and means within an acceptable range of deviation for a particular value as determined by one of ordinary skill in the art, taking into account the measurement in question and errors associated with the measurement of the particular quantity (i.e., limitations of the measurement system). For example, "about" can mean within one or more standard deviations, or within ±10% or ±5% of the stated value.

[0025] Unless otherwise specified herein, the enumeration of numerical ranges is intended only to be used as a shorthand method for individually referring to each individual value falling within the range, and each individual value is included in the specification as if it were individually listed herein. The endpoints of all ranges are included within the range and can be independently combined. As used herein, unless otherwise specified in the context, all numerical values ​​or numerical ranges include integers within such ranges and fractions of these values ​​or integers within the range. Therefore, for example, references to 90% to 100% ranges include 91%, 92%, 93%, 94%, 95%, 95%, 97%, etc., and 91.1%, 91.2%, 91.3%, 91.4%, 91.5%, etc., 92.1%, 92.2%, 92.3%, 92.4%, 92.5%, etc. All methods described herein can be performed in a suitable order, unless otherwise specified herein or clearly contradictory to the context.

[0026] The use of the terms "a", "an", and "the" and similar referents (especially in the context of the following claims) should be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. The terms first, second, etc. as used herein are not meant to indicate any particular order, but are merely for convenience to indicate, for example, multiple layers.

[0027] The terms "comprising," "having," "including," and "containing" are to be construed as open-ended terms (ie, meaning "including, but not limited to,") unless otherwise noted.

[0028] The use of any and all examples or exemplary language (e.g., "such as") is intended merely to better illuminate the disclosure and does not pose a limitation on the scope of the disclosure unless otherwise claimed. No language in the specification should be construed as indicating any non-claimed element as essential to the practice of the disclosure as used herein.

[0029] Although the present disclosure has been described with reference to exemplary embodiments, those skilled in the art will understand that various changes can be made and elements of the present disclosure can be replaced with equivalents without departing from the scope of the present disclosure. Additionally, many modifications can be made to adapt a particular situation or material to the teachings of the present disclosure without departing from the basic scope of the present disclosure. Therefore, the intention of the present disclosure is not limited to the particular embodiments disclosed as the best mode contemplated for carrying out the present disclosure, but rather the present disclosure will include all embodiments falling within the scope of the claims.

[0030] The term "control" with respect to weeds includes controlling weeds and protecting plants, parts of plants, or plant seeds from attack or infestation by said weeds.

[0031] Unless otherwise stated, the various amounts expressed as "% " or "% w / w" refer to the weight percentage of the total composition.

[0032] As used herein, the term "agrochemical" refers to all active substances that can be used in the field of agrochemicals, namely fungicides, bactericides, insecticides, acaricides, nematicides, molluscicides, rodenticides, repellents, plant growth regulators, herbicides, safeners, and phyto-nutrients. Hereinafter, the term "herbicide" encompasses both herbicides and plant growth regulators, provided that it does not otherwise emerge from the context.

[0033] As used herein, the term "herbicide" denotes a compound that controls or modifies the growth of unwanted weeds / plants.

[0034] The term "herbicidally effective amount" indicates the amount of such a compound or combination of such compounds that is capable of controlling or modifying the growth of harmful plants / unwanted plants / weeds. Control effects include all deviations from natural development, such as: killing, growth retardation, leaf burn, albinism, dwarfism, etc.

[0035] The term "plant" refers to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stalks, stems, leaves, and fruits. The term "site" refers to the area where a crop is planted or the location where weeds occur or grow or may occur or grow, and is intended to include soil, growth media other than soil.

[0036] As used herein, the term "pre-emergence" refers to the time point before the emergence of seedlings from the ground. When any herbicide is applied in the pre-emergence stage, it prevents the establishment of germinated weed seedlings.

[0037] As used herein, the term "post-emergence" refers to the time point after the emergence of seedlings from the ground. When any herbicide is applied in the post-emergence stage, it prevents the growth of germinated weed seedlings.

[0038] As used herein, "kraft pulp-lignosulfonate" refers to a low molecular weight dispersant with a low degree of sulfonation. It is the main dispersant for dry-based and water-based agrochemicals and also the main dispersant for disperse dye formulations. Kraft pulp lignosulfonate is sodium lignosulfonate with a sulfonation degree of 0.5.

[0039] In developing water-dispersible granules (WG or WDG) containing anilide herbicides and pyrimidinylsulfonylurea herbicides, the inventors of the present disclosure surprisingly found that the use of a combination of wetting agents and dispersants can maintain the integrity of the WDG. The combination of wetting agents and dispersants in a specific ratio is beneficial for the formation of the WDG. It was found that the selected combination of wetting agents and dispersants in a selected weight ratio can successfully maintain the integrity of the active ingredients in the formulation, thereby improving suspension and dispersibility and increasing the retention rate of wet sieving.

[0040] Accordingly, in one embodiment, the present disclosure provides a stable agrochemical composition.

[0041] Accordingly, in one embodiment, the present disclosure provides a stable herbicidal composition.

[0042] Another object of the present disclosure is to provide an agrochemical composition comprising a PS II photosynthesis inhibitor herbicide and an acetolactate synthase inhibitor herbicide.

[0043] Another object of the present disclosure is to provide an agrochemical composition comprising at least one PS II photosynthesis inhibitor herbicide and at least one acetolactate synthase inhibitor herbicide.

[0044] In another embodiment, the PS II photosynthesis inhibitor herbicide comprises triazine, triazinone, uracil, phenylcarbamate, urea, amide, or a combination thereof.

[0045] In a preferred embodiment, the PS II photosynthesis inhibitor herbicide comprises amide herbicides.

[0046] In a preferred embodiment, the amide herbicides comprise acetamide herbicides, anilide herbicides, or a combination thereof.

[0047] In another embodiment, the acetolactate synthase inhibitor herbicide comprises imidazolinone, triazolopyrimidine type-1, triazolopyrimidine type-2, triazolinone, sulfonanilide, pyrimidinyl benzoate, sulfonylurea, or a combination thereof.

[0048] In a preferred embodiment, the acetolactate synthase inhibitor herbicide comprises sulfonylurea herbicides.

[0049] In a preferred embodiment, the sulfonylurea herbicide comprises a pyrimidinylsulfonylurea herbicide, a sulfonylaminocarbonyltriazolinone herbicide, a triazinylsulfonylurea herbicide, or a combination thereof.

[0050] In another embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0051] In another embodiment, the present disclosure provides an agrochemical composition comprising at least one aniline herbicide and at least one pyrimidinylsulfonylurea herbicide.

[0052] As used throughout the present disclosure, the aniline herbicide, the pyrimidinylsulfonylurea herbicide or other active ingredient components include their salts, esters, ethers, polymorphs (including solvates and hydrates). Salts include salts that maintain the biological effectiveness and properties of the active ingredient and are not biologically or otherwise undesirable, and include derivatives of the disclosed compounds, wherein the parent compound is modified by preparing its inorganic and organic, non-toxic, acid or base addition salts. The salts can be synthesized from the parent compound by conventional chemical methods.

[0053] In one embodiment, the aniline herbicide is selected from the group consisting of: propanil, butachlor, pretilachlor, cinmethylin, dichlorohexanoyl aniline (erlujixiancaoan), ethoxyfen-ethyl, heptanoyl aniline, solan, or a combination thereof.

[0054] In a preferred embodiment, the aniline herbicide is propanil.

[0055] In one embodiment, the pyrimidinylsulfonylurea herbicide is selected from the group consisting of: propazine, amidosulfuron, tetraazasulfuron, bensulfuron-methyl, chlorimuron-ethyl, cyclosulfamuron, ethoxysulfuron, flazasulfuron, flucarbazone-sodium, foramsulfuron, halosulfuron-methyl, halosulfuron-methyl, mesosulfuron-methyl, bispyribac-sodium, thifensulfuron-methyl, monosulfuron, monosulfuron ester, nicosulfuron, orthosulfamuron, oxyfluorfen, flupyrsulfuron-methyl-sodium, pyrazosulfuron-ethyl, rimsulfuron, sulfosulfuron, trifloxysulfuron-sodium, sulfentrazone, or a combination thereof.

[0056] In a preferred embodiment, the pyrimidinylsulfonylurea herbicide is propazine.

[0057] In one embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide, wherein the aniline herbicide is propanil.

[0058] In one embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide, wherein the pyrimidinylsulfonylurea herbicide is promethazinesulfuron-methyl.

[0059] In another embodiment, the present disclosure provides an agricultural chemical composition comprising propanil and promethazinesulfuron-methyl.

[0060] According to one embodiment of the present disclosure, the agricultural chemical composition comprises about 10% w / w to about 90% w / w of the aniline herbicide based on the total weight of the agricultural chemical composition.

[0061] According to one embodiment of the present disclosure, the agricultural chemical composition comprises about 20% w / w to about 80% w / w of the aniline herbicide based on the total weight of the agricultural chemical composition.

[0062] According to one embodiment of the present disclosure, the agricultural chemical composition comprises about 30% w / w to about 70% w / w of the aniline herbicide based on the total weight of the agricultural chemical composition.

[0063] According to one embodiment of the present disclosure, the agricultural chemical composition comprises about 50% w / w to about 70% w / w of the aniline herbicide, based on the total weight of the agricultural chemical composition.

[0064] In a preferred embodiment, the agricultural chemical composition comprises about 60% w / w to about 62.5% w / w of the aniline herbicide based on the total weight of the agricultural chemical composition.

[0065] In one embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide, wherein the composition comprises about 50% w / w to about 70% w / w of the aniline herbicide based on the total weight of the agrochemical composition.

[0066] In one embodiment, the present disclosure provides an agricultural chemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide, wherein the composition comprises about 50% w / w to about 70% w / w of propanil based on the total weight of the agricultural chemical composition.

[0067] In a preferred embodiment, the agrochemical composition comprises about 60% w / w to about 62.5% w / w of propanil, based on the total weight of the agrochemical composition.

[0068] In a preferred embodiment, the agrochemical composition comprises about 60% w / w propanil, based on the total weight of the agrochemical composition.

[0069] According to one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 50% w / w of a pyrimidinylsulfonylurea herbicide.

[0070] According to one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 30% w / w of a pyrimidinylsulfonylurea herbicide.

[0071] According to one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide.

[0072] In a preferred embodiment, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 2% w / w to about 2.15% w / w of a pyrimidinylsulfonylurea herbicide.

[0073] In one embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide, wherein based on the total weight of the agrochemical composition, the composition comprises from about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide.

[0074] In one embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide, wherein based on the total weight of the agrochemical composition, the composition comprises from about 1% w / w to about 15% w / w of pyrazosulfuron-ethyl.

[0075] In a preferred embodiment, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 2% w / w to about 2.15% w / w of pyrazosulfuron-ethyl.

[0076] In a preferred embodiment, based on the total weight of the agrochemical composition, the agrochemical composition comprises about 2% w / w of pyrazosulfuron-ethyl.

[0077] In one embodiment, the present disclosure provides an agrochemical composition, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 50% w / w to about 70% w / w of an aniline herbicide and from about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide.

[0078] In one embodiment, the present disclosure provides an agrochemical composition that, based on the total weight of the agrochemical composition, comprises from about 50% w / w to about 70% w / w of propanil and from about 1% w / w to about 15% w / w of propyrisulfuron.

[0079] In another preferred embodiment, the composition comprises from about 50% w / w to about 70% w / w of an aniline herbicide and from about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide, based on the total weight of the composition.

[0080] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, and at least one dispersant.

[0081] In another embodiment, the present disclosure provides a weeding composition that comprises:

[0082] (a) an aniline herbicide;

[0083] (b) a pyrimidinylsulfonylurea herbicide;

[0084] (c) at least one wetting agent;

[0085] (d) at least one dispersant; and

[0086] (e) at least one agrichemically acceptable excipient.

[0087] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, and at least one dispersant, wherein the aniline herbicide is propanil.

[0088] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, and at least one dispersant, wherein the pyrimidinylsulfonylurea herbicide is propyrisulfuron.

[0089] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, propyrisulfuron, at least one wetting agent, and at least one dispersant.

[0090] According to one embodiment of the present disclosure, the at least one wetting agent comprises alkyl sulfates.

[0091] According to a preferred embodiment, the alkyl sulfates include sodium alkyl sulfate (which includes sodium lauryl sulfate), potassium lauryl sulfate, ammonium lauryl sulfate, or a combination thereof, preferably sodium lauryl sulfate.

[0092] In another embodiment, the wetting agent comprises an alkyl sulfate selected from sodium lauryl sulfate, potassium lauryl sulfate, ammonium lauryl sulfate, or a combination thereof.

[0093] According to one embodiment of the present disclosure, the at least one dispersant is selected from the group consisting of polycarboxylate dispersants, lignosulfonates, kraft pulp - lignosulfonates, sodium lignosulfonate, calcium lignosulfonate, potassium lignosulfonate, salts of lignosulfonic acid, or a combination thereof.

[0094] According to a preferred embodiment, the polycarboxylate dispersant comprises sodium polycarboxylate, potassium polycarboxylate, super - high - speed polymer dispersants, ammonium salts of polyelectrolytes, dispersant polymers, acrylic copolymers, acidic resin copolymers, styrene - acrylic polymers, and sodium salts of maleic anhydride copolymers, or a combination thereof, preferably potassium polycarboxylate.

[0095] In another embodiment, the dispersant is selected from the group consisting of potassium polycarboxylate, sodium polycarboxylate, lignosulfonates, kraft pulp - lignosulfonates, sodium lignosulfonate, calcium lignosulfonate, potassium lignosulfonate, salts of lignosulfonic acid, acrylic copolymers, acidic resin copolymers, styrene - acrylic polymers, and sodium salts of maleic anhydride copolymers, or a combination thereof.

[0096] According to an embodiment, the present disclosure provides an agrochemical composition, the agrochemical composition comprising:

[0097] a) an aniline herbicide;

[0098] b) a pyrimidinylsulfonylurea herbicide;

[0099] c) at least one wetting agent; and

[0100] d) at least one dispersant.

[0101] According to an embodiment, the present disclosure provides an agrochemical composition, the agrochemical composition comprising:

[0102] a) propanil;

[0103] b) pyrazosulfuron - ethyl;

[0104] c) at least one wetting agent; and

[0105] d) at least one dispersant.

[0106] According to an embodiment, the present disclosure provides an agrochemical composition, the agrochemical composition comprising:

[0107] a) propanil;

[0108] b) Prozacsulfuron-methyl;

[0109] c) alkyl sulfates; and

[0110] d) Polycarboxylate dispersants.

[0111] According to a preferred embodiment, the present disclosure provides an agrochemical composition, comprising:

[0112] a) Propanil;

[0113] b) Prozacsulfuron-methyl;

[0114] c) sodium lauryl sulfate; and

[0115] d) Polycarboxylate dispersants.

[0116] According to a preferred embodiment, the present disclosure provides an agrochemical composition, comprising:

[0117] a) Propanil;

[0118] b) Prozacsulfuron-methyl;

[0119] c) alkyl sulfates; and

[0120] d) Potassium polycarboxylate.

[0121] According to a preferred embodiment, the present disclosure provides an agrochemical composition, comprising:

[0122] a) Propanil;

[0123] b) Prozacsulfuron-methyl;

[0124] c) sodium lauryl sulfate; and

[0125] d) Potassium polycarboxylate.

[0126] According to a preferred embodiment, the present disclosure provides an agrochemical composition, comprising:

[0127] a) propanil present in an amount from about 60% w / w to about 62.5% w / w based on the total weight of the composition;

[0128] b) promethazinesulfuron-methyl present in an amount from about 2% w / w to about 2.15% w / w based on the total weight of the composition;

[0129] c) sodium lauryl sulfate; and

[0130] d) Potassium polycarboxylate.

[0131] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 30% w / w of an alkyl sulfate.

[0132] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 20% w / w of an alkyl sulfate.

[0133] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 10% w / w of an alkyl sulfate.

[0134] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 1% w / w to about 10% w / w of an alkyl sulfate.

[0135] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 2.5% w / w to about 3.5% w / w of an alkyl sulfate.

[0136] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 2.5% w / w to about 3.5% w / w of sodium lauryl sulfate.

[0137] In one embodiment, the present disclosure provides an agrochemical composition which, based on the total weight of the agrochemical composition, comprises from about 50% w / w to about 70% w / w of an aniline herbicide, from about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide and from about 2.5% w / w to about 3.5% w / w of an alkyl sulfate.

[0138] In one embodiment, the present disclosure provides an agrochemical composition which, based on the total weight of the agrochemical composition, comprises from about 50% w / w to about 70% w / w of propanil, from about 1% w / w to about 15% w / w of pyrazosulfuron-ethyl and from about 2.5% w / w to about 3.5% w / w of sodium lauryl sulfate.

[0139] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 30% w / w of a polycarboxylate dispersant.

[0140] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 20% w / w of a polycarboxylate dispersant.

[0141] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 0.1% w / w to about 10% w / w of a polycarboxylate dispersant.

[0142] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 1% w / w to about 10% w / w of a polycarboxylate dispersant.

[0143] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 6.8% w / w to about 7.5% w / w of a polycarboxylate dispersant.

[0144] In one embodiment of the present disclosure, based on the total weight of the agrochemical composition, the agrochemical composition comprises from about 6.8% w / w to about 7.5% w / w of potassium polycarboxylate.

[0145] In another preferred embodiment, the composition comprises from about 1% w / w to about 10% w / w of a wetting agent and from about 1% w / w to about 10% w / w of a dispersant, based on the total weight of the composition.

[0146] In one embodiment, the present disclosure provides an agrochemical composition which, based on the total weight of the agrochemical composition, comprises from about 50% w / w to about 70% w / w of an aniline herbicide, from about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide and from about 6.8% w / w to about 7.5% w / w of a polycarboxylate dispersant.

[0147] In one embodiment, the present disclosure provides an agrochemical composition which, based on the total weight of the agrochemical composition, comprises from about 50% w / w to about 70% w / w of propanil, from about 1% w / w to about 15% w / w of procarbazone-sodium and from about 6.8% w / w to about 7.5% w / w of potassium polycarboxylate.

[0148] In one embodiment, the present disclosure provides an agrochemical composition which, based on the total weight of the agrochemical composition, comprises from about 50% w / w to about 70% w / w of propanil, from about 1% w / w to about 15% w / w of procarbazone-sodium, from about 2.5% w / w to about 3.5% w / w of sodium lauryl sulfate and from about 6.8% w / w to about 7.5% w / w of potassium polycarboxylate.

[0149] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising:

[0150] a) Propanil present in an amount of about 60% w / w to about 62.5% w / w of the total weight of the composition;

[0151] b) Pyribenzoxim present in an amount of about 2% w / w to about 2.15% w / w of the total weight of the composition;

[0152] c) Sodium lauryl sulfate present in an amount of about 2.5% w / w to about 5.5% w / w of the total weight of the composition; and

[0153] d) Potassium polycarboxylate present in an amount of about 6.8% w / w to about 7.5% w / w of the total weight of the composition.

[0154] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersant, wherein the at least one wetting agent and the at least one dispersant are present in a weight ratio of about 0.1:1 to about 100:1, preferably about 0.1:1 to about 90:1, preferably about 0.1:1 to about 80:1, preferably about 0.1:1 to about 70:1, preferably about 0.1:1 to about 60:1, preferably about 0.1:1 to about 50:1, preferably about 0.1:1 to about 40:1, preferably about 0.1:1 to about 30:1, preferably about 0.1:1 to about 20:1.

[0155] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersant, wherein the at least one wetting agent and the at least one dispersant are present in a weight ratio of about 0.1:1 to about 10:1.

[0156] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyribenzoxim, at least one wetting agent and at least one dispersant, wherein the at least one wetting agent and the at least one dispersant are present in a weight ratio of about 0.1:1 to about 10:1.

[0157] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate and a polycarboxylate dispersant, wherein the alkyl sulfate and the polycarboxylate dispersant are present in a weight ratio of about 0.1:1 to about 10:1.

[0158] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate, and a polycarboxylate dispersant, wherein the alkyl sulfate and the polycarboxylate are present in a weight ratio of from about 0.1:1 to about 10:1.

[0159] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, sodium lauryl sulfate, and potassium polycarboxylate, wherein the sodium lauryl sulfate and the potassium polycarboxylate are present in a weight ratio of from about 0.1:1 to about 10:1.

[0160] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, and potassium polycarboxylate, wherein the sodium lauryl sulfate and the potassium polycarboxylate are present in a weight ratio of from about 0.1:1 to about 10:1.

[0161] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, and potassium polycarboxylate, wherein the sodium lauryl sulfate and the potassium polycarboxylate are present in a weight ratio of about 0.36:1.

[0162] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, and potassium polycarboxylate, wherein the sodium lauryl sulfate and the potassium polycarboxylate are present in a weight ratio of about 0.46:1.

[0163] Unless otherwise specified, the ratios disclosed throughout the specification are weight ratios.

[0164] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, and at least one dispersant, wherein the aniline herbicide and the pyrimidinylsulfonylurea herbicide are present in a weight ratio of from about 10:1 to about 100:1.

[0165] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, and at least one dispersant, wherein the aniline herbicide and the pyrimidinylsulfonylurea herbicide are present in a weight ratio of from about 20:1 to about 80:1.

[0166] According to an embodiment of the present disclosure, the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, and at least one dispersant, wherein the aniline herbicide and the pyrimidinylsulfonylurea herbicide are present in a weight ratio of from about 20:1 to about 50:1.

[0167] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyribenzoxim, alkyl sulfate, and polycarboxylate dispersant, wherein propanil and pyribenzoxim are present in a weight ratio of about 20:1 to about 50:1.

[0168] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyribenzoxim, sodium lauryl sulfate, and potassium polycarboxylate, wherein propanil and pyribenzoxim are present in a weight ratio of about 20:1 to about 50:1.

[0169] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyribenzoxim, sodium lauryl sulfate, and potassium polycarboxylate, wherein propanil and pyribenzoxim are present in a weight ratio of about 30:1.

[0170] According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, pyribenzoxim, sodium lauryl sulfate, and potassium polycarboxylate, wherein propanil and pyribenzoxim are present in a weight ratio of about 29.06:1.

[0171] In another embodiment, the inventors of the present disclosure found that when mixed with alkyl sulfate and polycarboxylate dispersant, the combination of propanil and pyribenzoxim showed excellent suspension and wet sieve retention rate.

[0172] In another embodiment, the inventors of the present disclosure noted that when produced according to the present disclosure, it is easy to prepare the composition using propanil, pyribenzoxim, alkyl sulfate, and polycarboxylate dispersant.

[0173] According to one embodiment, the agrochemical composition obtained according to the present disclosure can be quickly dispersed in water. According to one embodiment, the agrochemical composition obtained according to the present disclosure produces optimal suspension when dispersed in water.

[0174] According to one embodiment, the present disclosure provides an agrochemical composition comprising propanil and pyribenzoxim, which has excellent suspension and wet sieve retention rate. The composition has several advantages, such as easy handling, easy use, reduced workplace exposure, reduced toxicity, reduced spillage and waste disposal, less field drift, free flowing, and significantly reduced dust hazard.

[0175] In another embodiment, the present disclosure provides an agrochemical composition, which comprises:

[0176] a) propanil;

[0177] b) pyribenzoxim;

[0178] c) sodium lauryl sulfate; and

[0179] d) potassium polycarboxylate,

[0180] Wherein when measured according to the physical and chemical determination methods (MT) 184 and / or MT 184.1 of the Collaborative International Pesticides Analytical Council (CIPAC) guidelines, the composition exhibits a suspension rate greater than about 75% w / w.

[0181] In another embodiment, the present disclosure provides an agrochemical composition comprising:

[0182] a) Propanil;

[0183] b) Pyribenzoxim;

[0184] c) Sodium lauryl sulfate; and

[0185] d) Potassium polycarboxylate,

[0186] Wherein when measured according to CIPAC guideline MT 185, the composition exhibits a wet sieve retention rate of less than about 0.1% w / w.

[0187] In another embodiment, the present disclosure provides an agrochemical composition comprising:

[0188] a) Propanil present in an amount of about 60% w / w to about 62.5% w / w of the total weight of the composition;

[0189] b) Pyribenzoxim present in an amount of about 2% w / w to about 2.15% w / w of the total weight of the composition;

[0190] c) Sodium lauryl sulfate present in an amount of about 2.5% w / w to about 3.5% w / w of the total weight of the composition; and

[0191] d) Potassium polycarboxylate present in an amount of about 6.8% w / w to about 7.5% w / w of the total weight of the composition,

[0192] Wherein when measured according to CIPAC guidelines MT 184 and / or MT 184.1, the composition exhibits a suspension rate greater than about 75% w / w; and

[0193] Wherein when measured according to CIPAC guideline MT 185, the composition exhibits a wet sieve retention rate of less than about 0.1% w / w.

[0194] In another embodiment, when measured according to CIPAC guidelines MT 184 and / or MT 184.1, the composition exhibits a suspension rate greater than 80% w / w, preferably greater than about 85% w / w.

[0195] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant, and at least one agrochemically acceptable excipient.

[0196] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, pyrazosulfuron-ethyl, at least one wetting agent, at least one dispersant, and at least one agrochemically acceptable excipient.

[0197] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, pyrazosulfuron-ethyl, alkyl sulfates, polycarboxylate dispersants, and at least one agrochemically acceptable excipient.

[0198] According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient.

[0199] In another embodiment, the present disclosure provides an agrochemical composition comprising:

[0200] a) propanil;

[0201] b) pyrazosulfuron-ethyl;

[0202] c) sodium lauryl sulfate;

[0203] d) potassium polycarboxylate; and

[0204] e) at least one agrochemically acceptable excipient.

[0205] According to one embodiment of the present disclosure, the agrochemically acceptable excipient is selected from one or more of the following: emulsifiers, colorants, thickeners / binders, antifreezes, defoamers, antioxidants, solvents, preservatives, glidants, anticaking agents, pH regulators, buffers, formulation aids, disintegrants, inert substances, wetting agents, or combinations thereof.

[0206] In another embodiment, the emulsifiers useful herein can be readily determined by those skilled in the art and include various nonionic emulsifiers, anionic emulsifiers, cationic emulsifiers, and amphoteric emulsifiers, or blends of two or more emulsifiers. Examples of nonionic emulsifiers useful for preparing emulsifiable concentrates include polyalkylene glycol ethers and condensation products of alkylphenols and arylphenols, aliphatic alcohols, aliphatic amines, or fatty acids with ethylene oxide, propylene oxide (such as ethoxylated alkylphenols), and carboxylate esters solubilized with polyols or polyoxyalkylene. Cationic emulsifiers include quaternary ammonium compounds and fatty amine salts. Anionic emulsifiers include oil-soluble salts of alkylarylsulfonic acids (e.g., calcium), oil-soluble salts of sulfated polyethylene glycol ethers, and suitable salts of phosphorylated polyethylene glycol ethers.

[0207] In one embodiment, the colorant can be selected from iron oxides, titanium oxides, and Prussian blue, as well as organic dyes such as alizarin dyes, azo dyes, or metal phthalocyanine dyes, and salts of trace elements such as iron, manganese, boron, copper, cobalt, molybdenum, and zinc.

[0208] In one embodiment, the thickener or gelling agent can be selected from, but not limited to, molasses, granulated sugar, alginates, karaya gum, guar gum, tragacanth gum, polysaccharide gums, mucilage, xanthan gum, or combinations thereof. In another embodiment, the binder can be selected from silicates (such as magnesium aluminum silicate), polyvinyl acetate, polyvinyl acetate copolymers, polyvinyl alcohol, polyvinyl alcohol copolymers, celluloses (including ethyl cellulose and methyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, hydroxymethylpropyl cellulose), polyvinyl pyrrolidone, dextrin, maltodextrin, polysaccharides, fats, oils, proteins, gum arabic, shellac, vinylidene chloride, vinylidene chloride copolymers, acrylic copolymers, starch, polyvinyl acrylate, zein, gelatin, carboxymethyl cellulose, chitosan, polyethylene oxide, acrylamide polymers and copolymers, hydroxyethyl acrylate, methacrylamide monomers, alginates, ethyl cellulose, polychloroprene, and their syrups or mixtures; polymers and copolymers of vinyl acetate, methyl cellulose, vinylidene chloride, acrylic acid, cellulose, polyvinyl pyrrolidone, and polysaccharides; polymers and copolymers of vinylidene chloride and vinyl acetate-ethylene copolymers; combinations of polyvinyl alcohol and sucrose; plasticizers such as glycerol, propylene glycol, polyethylene glycol.

[0209] In another embodiment, the antifreeze added to the composition can be an alcohol selected from the group consisting of, but not limited to, ethylene glycol, 1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, 1,4-pentanediol, 3-methyl-1,5-pentanediol, 2,3-dimethyl-2,3-butanediol, trimethylolpropane, mannitol, sorbitol, glycerol, pentaerythritol, 1,4-cyclohexanedimethanol, xylenol, bisphenols such as bisphenol A, etc. In addition, ether alcohols such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene oxide or polypropylene glycol with a molecular weight up to about 4000, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, triethylene glycol monomethyl ether, butoxyethanol, butanediol monobutyl ether, dipentaerythritol, tripentaerythritol, tetrapentaerythritol, diglycerol, triglycerol, tetraglycerol, pentaglycerol, hexaglycerol, heptaglycerol, octaglycerol.

[0210] According to one embodiment, the defoamer can be selected from polydimethoxysiloxane, polydimethylsiloxane, alkyl polyacrylate, castor oil, fatty acid, fatty acid ester, fatty acid sulfate, fatty alcohol, fatty alcohol ester, fatty alcohol sulfate, olive foot oil, monoglyceride and diglyceride, paraffin oil, paraffin wax, polypropylene glycol, silicone oil, vegetable fat, vegetable fat sulfate, vegetable oil, vegetable oil sulfate, vegetable wax, vegetable wax sulfate, silicon- or magnesium stearate-based reagents, and blends of maltodextrin and methylated silica.

[0211] The agrochemical composition may further comprise one or more antioxidants. Preferably, the agrochemical formulation comprises an antioxidant.Antioxidants are, for example, amino acids (such as glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles and imidazole derivatives (such as urocanic acid), peptides (such as D,L-carnosine, D-carnosine, L-carnosine and their derivatives (such as anserine)), carotenoids, carotenes (such as α-carotene, β-carotene, lycopene) and their derivatives, lipoic acid and its derivatives (such as dihydrolipoic acid), aurothioglucose, propylthiouracil and its further thio compounds (such as thioglycerol, thiosorbitol, mercaptoacetic acid, thioredoxin, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, pentyl, butyl, lauryl, palmitoyl, oleyl, γ-linolenyl, cholesteryl and glyceryl esters) and salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts), and sulfoximine compounds with a very low tolerance dose (such as buthionine sulfoximine, homocysteine sulfoximine, buthionine sulfone, pentathionine sulfoximine, hexathionine sulfoximine, heptathionine sulfoximine), as well as metal chelators (such as α-hydroxy fatty acids, EDTA, EGTA, phytic acid, lactoferrin), α-hydroxy acids (such as citric acid, lactic acid, malic acid), humic acid, bile acids, bile extracts, gallate esters (such as propyl gallate, octyl gallate and dodecyl gallate), flavonoids, catechins, bilirubin, biliverdin and their derivatives, unsaturated fatty acids and their derivatives (such as γ-linolenic acid, linoleic acid, arachidonic acid, oleic acid), folic acid and its derivatives, hydroquinones and their derivatives (such as arbutin), ubiquinone and panthenol and their derivatives, vitamin C and its derivatives (such as ascorbyl palmitate, stearate, dipalmitate, acetate, magnesium ascorbyl phosphate, sodium and magnesium ascorbate, disodium ascorbyl phosphate and disodium ascorbyl sulfate, potassium ascorbyl tocopheryl phosphate, chitosan ascorbate), isoascorbic acid and its derivatives, tocopherols and their derivatives (such as tocopheryl acetate, linoleate, oleate and succinate, tocopheryl polyethylene glycol-5, tocopheryl polyethylene glycol-10, tocopheryl polyethylene glycol-12, tocopheryl polyethylene glycol-18, tocopheryl polyethylene glycol-50, tocotrienol), vitamin A and its derivatives (such as vitamin A palmitate), coniferyl benzoate of benzoin resin, rutin, rutinic acid and its derivatives, disodium rutin disulfate, cinnamic acid and its derivatives (such as ferulic acid, ethyl ferulic acid, caffeic acid), kojic acid, chitosan glycolate and salicylate, butylated hydroxytoluene, butylated hydroxyanisole, nordihydroguaiaretic acid, dehydrodiconiferyl alcohol, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, selenium and selenium derivatives (such as selenomethionine), stilbenes and stilbene derivatives (such as oxyresveratrol, trans-oxyresveratrol).According to the present disclosure, suitable derivatives of these antioxidants (salts, esters, sugars, nucleotides, nucleosides, peptides, and lipids) and mixtures or plant extracts of these specified active ingredients (e.g., tea tree oil, rosemary extract, and rosmarinic acid) can be used. Generally, mixtures of the above antioxidants are possible.

[0212] According to one embodiment, examples of suitable solvents are water, vegetable oils, or derivatives. In principle, solvent mixtures can also be used.

[0213] In another embodiment, suitable preservatives are, for example, benzothiazole, 1,2 - benzisothiazolin - 3 - one, dichloro - s - triazinetrione sodium, sodium benzoate, potassium sorbate, 1,2 - phenyl - isothiazolin - 3 - one, chloroxylenol, butyl - p - hydroxybenzoate, benzoic acid, and combinations thereof.

[0214] In another embodiment, suitable inert substances are, for example, precipitated silica, amorphous silica, titanium dioxide, kaolin, bentonite, soapstone, talc, attapulgite, ceramics, montmorillonite, pumice, sepiolite, diatomaceous earth, sand, clay, dolomite, calcite, magnesium oxide, magnesium carbonate, sucrose, corn starch, citric acid and its salts, and combinations thereof.

[0215] In one embodiment, the wetting agent can be selected from dialkyl naphthalene sulfonate formaldehyde condensates, sodium salts of dialkyl naphthalene sulfonates, and sodium naphthalene sulfonate - formaldehyde condensates.

[0216] In another embodiment, the composition contains from about 0.1% w / w to about 30% w / w of an agrochemically acceptable excipient, based on the total weight of the composition.

[0217] According to one embodiment, the present disclosure provides an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant, and at least one agrochemically acceptable excipient, wherein the agrochemical composition is in the form of a solid preparation.

[0218] In one embodiment, the agrochemical composition is selected from powders for dry soil application (DS), granules / soil application (GR), controlled - release (slow or fast) granules (CR), Jambo balls or bags (bags in water - soluble sachets), water - soluble granules (SG), water - dispersible granules (WG or WDG), or soil - applied granules (SAG).

[0219] According to one embodiment, the agrochemical composition is in the form of water - dispersible granules (WG or WDG).

[0220] In another embodiment, the composition is in the form of water - dispersible granules.

[0221] In another embodiment, the present disclosure provides a water-dispersible granule composition comprising:

[0222] a) Aniline herbicides;

[0223] b) pyrimidinylsulfonylurea herbicides;

[0224] c) at least one wetting agent;

[0225] d) at least one dispersant; and

[0226] e) at least one agrochemically acceptable excipient.

[0227] In another embodiment, the present disclosure provides a water-dispersible granule composition comprising:

[0228] a) Propanil;

[0229] b) Prozacsulfuron-methyl;

[0230] c) alkyl sulfates;

[0231] d) a polycarboxylate dispersant; and

[0232] e) at least one agrochemically acceptable excipient.

[0233] In another embodiment, the present disclosure provides a water-dispersible granule composition comprising:

[0234] a) Propanil;

[0235] b) Prozacsulfuron-methyl;

[0236] c) alkyl sulfates;

[0237] d) polycarboxylates; and

[0238] e) at least one agrochemically acceptable excipient.

[0239] In another embodiment, the present disclosure provides a water-dispersible granule composition comprising:

[0240] a) Propanil;

[0241] b) Prozacsulfuron-methyl;

[0242] c) sodium lauryl sulfate;

[0243] d) potassium polycarboxylate; and

[0244] e) at least one agrochemically acceptable excipient.

[0245] In one embodiment, the present invention provides a WDG composition in the form of a tank mix or a pre-formulated (premixed) composition, the WDG composition comprising propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, potassium polycarboxylate and at least one agrichemically acceptable excipient.

[0246] In one embodiment, the present invention provides a WDG composition in the form of a pre-formulated (premixed) composition, the WDG composition comprising propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, potassium polycarboxylate and at least one agrichemically acceptable excipient.

[0247] In another embodiment, the present disclosure provides a premixed WDG composition, the premixed WDG composition comprising:

[0248] a) propanil;

[0249] b) pyrazosulfuron-ethyl;

[0250] c) sodium lauryl sulfate;

[0251] d) potassium polycarboxylate; and

[0252] e) at least one agrichemically acceptable excipient.

[0253] On the other hand, the present disclosure provides a method for preparing an agrichemical composition, wherein the agrichemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant and at least one agrichemically acceptable excipient.

[0254] On the other hand, the present disclosure provides a method for preparing the herbicidal composition, the method comprising:

[0255] (a) mixing an aniline herbicide with a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant and at least one agrichemically acceptable excipient to obtain a mixture;

[0256] (b) grinding the mixture obtained in step (a);

[0257] (c) using the mixture to prepare a dough;

[0258] (d) extruding the dough to obtain granules; and

[0259] (e) drying the granules to obtain the herbicidal composition.

[0260] On the other hand, the present disclosure provides a method for preparing the agrichemical composition, the method comprising:

[0261] (a) Mix an aniline herbicide with a pyrimidinylsulfonylurea herbicide, an alkyl sulfate, a polycarboxylate dispersant, and at least one agrichemically acceptable excipient to obtain a mixture;

[0262] (b) Grind the mixture obtained in step (a);

[0263] (c) Use the mixture to prepare a dough;

[0264] (d) Extrude the dough to obtain granules; and

[0265] (e) Dry the granules to obtain the agrichemical composition.

[0266] In another aspect, the present disclosure provides a method for preparing the agrichemical composition, the method comprising:

[0267] (a) Mix propanil with pyrazosulfuron-ethyl, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrichemically acceptable excipient to obtain a mixture;

[0268] (b) Grind the mixture obtained in step (a);

[0269] (c) Use the mixture to prepare a dough;

[0270] (d) Extrude the dough to obtain granules; and

[0271] (e) Dry the granules to obtain the agrichemical composition.

[0272] It will be readily understood by those skilled in the art that the essence of the method for preparing the composition described in the embodiments of the present disclosure is not carried out in the given order. For example, grinding the mixture in step (a) and preparing the dough can be carried out simultaneously, and preparing the dough does not need to be carried out only after grinding the mixture in step (a) as provided in the embodiments. In addition, in step (a), the mixing of propanil with pyrazosulfuron-ethyl, alkyl sulfate, and polycarboxylate dispersant can be carried out by mixing all components simultaneously, or the alkyl sulfate and / or polycarboxylate dispersant can be first mixed with propanil or pyrazosulfuron-ethyl separately and then mixed together.

[0273] In one embodiment, in step (b) of the method, a shear stirrer, a kneader, or a plow shear stirrer can be used.

[0274] In another embodiment, the drying of the granules is carried out in a fluidized bed dryer.

[0275] In another embodiment, the water content of the dried granules obtained in step (e) is less than about 2% w / w.

[0276] In one embodiment, the granules are dried in the temperature range of 45 °C to 50 °C to achieve a water content of less than about 2% w / w.

[0277] Those skilled in the art will also understand that similar suspension and wet sieve parameters can be obtained by preparing the granules by spray drying instead of extrusion, provided that the granules prepared by this method contain propanil, propoxycarbazone-sodium, alkyl sulfate and polycarboxylate dispersant.

[0278] In another embodiment, the present disclosure provides the use of the agrochemical composition for controlling weeds, wherein the agrochemical composition comprises an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0279] In another embodiment, the present disclosure provides the use of a herbicidal composition for controlling weeds, wherein the composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant and at least one agrichemically acceptable excipient.

[0280] In another embodiment, the present disclosure provides the use of the agrochemical composition for controlling weeds, wherein the agrochemical composition comprises an aniline herbicide, a pyrimidinylsulfonylurea herbicide, alkyl sulfate, polycarboxylate dispersant and at least one agrichemically acceptable excipient.

[0281] In another embodiment, the present disclosure provides the use of the agrochemical composition for controlling weeds, wherein the agrochemical composition comprises propanil, propoxycarbazone-sodium, sodium lauryl sulfate, potassium polycarboxylate and at least one agrichemically acceptable excipient.

[0282] On the other hand, the present disclosure provides a method for controlling weeds, the method comprising applying to the plant or its locus an agrochemical composition comprising an aniline herbicide and a pyrimidinylsulfonylurea herbicide.

[0283] On the other hand, the present disclosure provides a method for controlling weeds by applying an effective amount of a herbicidal composition to a plant or its locus, the composition comprising: an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant and at least one agrichemically acceptable excipient.

[0284] On the other hand, the present disclosure provides a method for controlling weeds, the method comprising applying to the plant or its locus an agrochemical composition comprising an aniline herbicide, a pyrimidinylsulfonylurea herbicide, alkyl sulfate, polycarboxylate dispersant and at least one agrichemically acceptable excipient.

[0285] On the other hand, the present disclosure provides a method for controlling weeds, the method comprising applying to the plant or its locus an agrochemical composition comprising propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, potassium polycarboxylate and at least one agriculturally chemically acceptable excipient.

[0286] In another embodiment, the composition of the present disclosure is used for controlling weeds in various crops. Non-limiting examples of weeds controlled by the composition of the present disclosure include: Cruciferous weeds: wild radish, radish, Sinapis arvensis, Capsella bursa-pastoris, mustard, rape, Descurainia pinnata, Ludwigia adscendens, Rorippa islandica, Thlaspi arvense, Lepidium virginicum, Coronopus didymus, Lepidium apetalum, and combinations thereof. Non-limiting examples of weeds controlled by the composition of the present disclosure include: Gramineous weeds: Dinebra retroflexa, Cynodon dactylon, Echinochloa colonum, Echinochloa crusgalli, Setaria viridis, Setaria faberi, Setaria glauca, Setaria ilosa ate, Digitaria ciliaris, Digitaria sanguinalis, Digitaria horizontalis, Digitaria insularis, Eleusine indica, Poa annua, Alopecurus aequalis, Alopecurus myosuroides, Avena fatua, Sorghum halepense, Sorghum vulgare, Agropyron repens, Lolium multiflorum, Lolium perenne, Lolium rigidum, Bromus secalinus, Bromus tectorum, Hordeum jubatum, Aegilops cylindrica, Phalaris arundinacea, Phalaris minor, Apera spicaventi, Panicum dichotomiflorum, Panicum texanum, Panicum maximum, Brachiaria reptains, Brachiariaplatyphylla), Brachiaria ruziziensis, Brachiaria plantaginea, Brachiaria decumbens, Brachiaria brizantha, Brachiaria humidicola, Brachiaria mutica, Cenchrus echinatus, Cenchrus pauciflorus, Eriochloa villosa, Pennisetum setosum, Chloris gayana, Chloris barbata, Eragrostis ilosa, Rhynchelitrum repens, Dactyloctenium aegyptium, Ischaemum rugosum, Oryza sativa, Paspalum notatum, Paspalum maritimum, Pennisetum clandestinum, Pennisetum setosum, Rottboellia cochinchinensis, and combinations thereof.

[0287] In another embodiment, the composition of the present disclosure is used to control weeds in various crops.

[0288] In another embodiment, examples of various (target) crops include, but are not limited to, corn, rice, wheat, barley, rye, oats, sorghum, cotton, soybeans, peanuts, buckwheat, beets, rapeseed, sunflowers, sugarcane, tobacco, etc.; vegetables: nightshade vegetables such as eggplant, tomato, sweet pepper, pepper, potato, etc., cucurbitaceae vegetables such as cucumber, pumpkin, zucchini, watermelon, melon, squash, etc., cruciferous vegetables such as radish, white radish, horseradish, cabbage, Chinese cabbage, cabbage, mustard, broccoli, cauliflower, etc., asteraceae vegetables such as burdock, crown daisy, artichoke, lettuce, etc., liliaceae vegetables such as green onion, onion, garlic, and asparagus, non-starchy (ammiaceous) vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceae vegetables such as spinach, lamb's lettuce, etc., lamiaceae vegetables such as shiso, mint, basil, etc., strawberry, sweet potato, Japanese yam, taro, etc., flowers, foliage plants, lawn grass, fruits: pome fruits such as apple, pear, citrus, etc., stone fruits such as peach, plum, nectarine, ume, cherry tomato, apricot, prune, etc., citrus fruits such as orange, lemon, lime, grapefruit, etc., nuts such as chestnut, walnut, hazelnut, almond, pistachio, cashew, macadamia, etc., berries such as blueberry, cranberry, blackberry, raspberry, etc., grape, persimmon, olive, plum, banana, coffee, date palm, coconut, etc., trees other than fruit trees; tea tree, mulberry tree, flowering plants, trees such as ash tree, birch tree, dogwood tree, eucalyptus tree, ginkgo tree, lilac tree, maple tree, oak tree, poplar tree, redbud tree, sweet gum tree, sycamore tree, beech tree, false cypress, fir tree, hemlock tree, juniper tree, pine tree, spruce tree, and yew tree, etc.

[0289] In one embodiment, the method for controlling weeds includes applying a premixed composition of propanil and pyrazosulfuron-ethyl.

[0290] In one embodiment, the premixed preparation is in the form of water-dispersible granules (WG or WDG).

[0291] According to one embodiment of the present disclosure, the various components of the agrochemical composition can be used alone, or have been partially or completely mixed with at least one other component to prepare the composition according to the present disclosure. They can also be packaged and further used as a composition, such as a kit.

[0292] According to one embodiment of the present disclosure, there is provided a kit that includes an aniline herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent, and at least one agrichemically acceptable excipient.

[0293] According to one embodiment of the present disclosure, there is provided a kit that includes an aniline herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate, a polycarboxylate dispersing agent, and at least one agrichemically acceptable excipient.

[0294] According to one embodiment, the kit comprises:

[0295] (a) an aniline herbicide;

[0296] (b) a pyrimidinylsulfonylurea herbicide;

[0297] (c) an alkyl sulfate;

[0298] (d) a polycarboxylate dispersant; and

[0299] (e) at least one agrichemically acceptable excipient;

[0300] And optionally further comprises:

[0301] Instructions for use.

[0302] According to one embodiment of the present disclosure, there is provided a kit comprising propanil, pyrazosulfuron-ethyl, sodium lauryl sulfate, potassium polycarboxylate and at least one agrichemically acceptable excipient.

[0303] According to one embodiment, the kit comprises:

[0304] (a) propanil;

[0305] (b) pyrazosulfuron-ethyl;

[0306] (c) sodium lauryl sulfate;

[0307] (d) potassium polycarboxylate; and

[0308] (e) at least one agrichemically acceptable excipient;

[0309] And optionally further comprises:

[0310] Instructions for use.

[0311] In one embodiment of the present disclosure, the kit may include one or more (including all) components that can be used to prepare an agrichemical concentrated composition. For example, the kit may include active ingredients and / or wetting agents and dispersants. One or more of the components may have been combined or pre-formulated. In those embodiments where more than two components are provided in the kit, the components may have been combined and thus packaged in a single container, such as a vial, bottle, can, sachet, bag or jar.

[0312] In view of the foregoing, several advantages of the present disclosure will be seen, and other beneficial results will also be obtained. Although the present disclosure has been fully disclosed, it should be understood that many additional modifications and variations can be made thereto without departing from the scope of the present disclosure. The embodiments can be combined together to better understand the present disclosure without departing from the scope of the present disclosure.

[0313] In another embodiment, the alternative or multiple embodiments of the present disclosure disclosed herein should not be construed as limiting. Each embodiment can be cited and claimed separately or in any combination with other embodiments of the present disclosure. For convenience and / or patentability reasons, one or more embodiments of the present disclosure can be included in or deleted from the present disclosure.

[0314] The present disclosure will now be described in more detail with reference to the following examples. Although the above written description of the present disclosure enables a person of ordinary skill in the art to make and use what is currently considered to be its best mode, the person of ordinary skill in the art will understand and recognize the existence of variations, combinations, and equivalents of the specific embodiments, methods, and examples herein. Therefore, the present disclosure should not be limited by the above embodiments, methods, and the following examples, but should be limited by all embodiments and methods within the scope and essence of the present disclosure. Detailed Description

[0315] Example :

[0316] Example 1: Propanil and pyribenzoxim WDG composition

[0317] The agrochemical composition of the present invention is formulated as water-dispersible granules (WG or WDG).

[0318]

[0319] Method :

[0320] Propanil is mixed with pyribenzoxim, alkyl sulfate (sodium lauryl sulfate), polycarboxylate dispersant (potassium polycarboxylate), and at least one agrochemically acceptable excipient to obtain a mixture. The mixture is ground and a dough is prepared. The dough is extruded to obtain granules. The obtained granules are dried in the temperature range of about 45°C to about -50°C to obtain the agrochemical composition.

[0321] Examples 2 - 5: Study on suspensibility and wet - sieve retention

[0322] The suspension and wet sieve retention studies were carried out on the compositions in Examples 2-5, and the results are listed in Table 1.

[0323] Table 1: Study on suspensibility and wet - sieve retention

[0324]

[0325] As can be seen from the results in Table 1, Examples 2 and 5 have a combination of an alkyl sulfate (sodium lauryl sulfate) and a polycarboxylate dispersant (potassium polycarboxylate). When examined according to CIPAC Method MT 184 and CIPAC Method MT 185, respectively, the compositions from these two examples exhibited a suspension of greater than 75% w / w and a wet sieve retention of less than 0.1% w / w. The compositions of Examples 3 and 4 do not have a combination of an alkyl sulfate (sodium lauryl sulfate) and a polycarboxylate dispersant (potassium polycarboxylate), and they do not have the desired properties, i.e., when examined according to CIPAC Method MT 184 and CIPAC Method MT 185, respectively, a suspension of greater than 75% w / w and a wet sieve retention of less than 0.1% w / w.

[0326] Therefore, sodium lauryl sulfate is essential for wet sieving, and potassium polycarboxylate is essential for suspension and dispersibility. Thus, it is clearly seen from the study of the suspension and wet sieve retention parameters that a combination of an alkyl sulfate and a polycarboxylate dispersant is essential for the compositions of propanil and pyrazosulfuron-ethyl to exhibit the desired suspension and wet sieve retention.

[0327] Example 6: Stability under AHS conditions

[0328] The stability of the water-dispersible granule composition disclosed in Example 1 was evaluated. The stability of the composition was continuously measured for about 14 days under accelerated heat stability (AHS) conditions at about 54 °C and has been disclosed in Table 2.

[0329] Table 2: Stability study

[0330]

[0331] After accelerated storage at 54 °C ± 2 °C for 14 days, there were no significant changes in the physical or chemical properties (i.e., active ingredient content, wet sieve test, and suspension) of the composition.

[0332] Example 7: Real - time data of stability study

[0333] The stability of the water-dispersible granule composition disclosed in Example 1 was evaluated. The stability of the composition was determined for 6, 12, 18, 24, and 30 months and is disclosed in Table 3.

[0334] Example 3: Stability study

[0335]

[0336] Therefore, it was observed that when stored for a period of 6 months to 30 months, propanil and pyribenzoxim WDG were stable.

Claims

1. A herbicidal composition, the herbicidal composition comprising: (a) an aniline herbicide; (b) a pyrimidinylsulfonylurea herbicide; (c) at least one wetting agent; (d) at least one dispersant; and (e) at least one agrochemically acceptable excipient.

2. The composition according to claim 1, wherein the aniline herbicide is selected from the group consisting of: propanil, butachlor, pretilachlor, cinmethylin, dichlormid, ethoxyfen-ethyl, heptanilide, pebulate, or combinations thereof.

3. The composition according to claim 1, wherein the pyrimidinylsulfonylurea herbicide is selected from the group consisting of: propazine, amidosulfuron, azimsulfuron, bensulfuron-methyl, chlorimuron-ethyl, cyclosulfamuron, ethoxysulfuron, flazasulfuron, flucarbazone-sodium, foramsulfuron, halosulfuron-methyl, halosulfuron-methyl sodium, halosulfuron-methyl potassium, halosulfuron-methyl salts, acrylic acid copolymer, acidic resin copolymer, styrene acrylic polymer, and maleic anhydride copolymer sodium salt, or combinations thereof.

4. The composition according to claim 1, wherein the wetting agent comprises an alkyl sulfate selected from sodium lauryl sulfate, potassium lauryl sulfate, ammonium lauryl sulfate, or combinations thereof.

5. The composition according to claim 1, wherein the dispersant is selected from the group consisting of: potassium polycarboxylate, sodium polycarboxylate, lignosulfonate, kraft pulp - lignosulfonate, sodium lignosulfonate, calcium lignosulfonate, potassium lignosulfonate, salts of lignosulfonic acid, acrylic acid copolymer, acidic resin copolymer, styrene acrylic polymer, and maleic anhydride copolymer sodium salt, or combinations thereof.

6. The composition according to claim 1, wherein the wetting agent and the dispersant are present in a weight ratio of about 0.1:1 to about 10:

1.

7. The composition according to claim 1, wherein the agrochemically acceptable excipient is selected from the group consisting of: emulsifier, colorant, thickener / binder, antifreeze, defoamer, antioxidant, solvent, preservative, glidant, anticaking agent, pH regulator, buffer, formulation aid, disintegrant, inert substance, wetting agent, or combinations thereof.

8. The composition according to claim 1, wherein the composition comprises about 50% w / w to about 70% w / w of an aniline herbicide based on the total weight of the composition and about 1% w / w to about 15% w / w of a pyrimidinylsulfonylurea herbicide based on the total weight of the composition.

9. The composition according to claim 1, wherein the composition comprises about 1% w / w to about 10% w / w of a wetting agent based on the total weight of the composition and about 1% w / w to about 10% w / w of a dispersant based on the total weight of the composition.

10. The composition according to claim 1, wherein the composition is in the form of water-dispersible granules.

11. A water-dispersible granule composition, the water-dispersible granule composition comprising: (a) propanil; (b) Prozacsulfuron-methyl; (c) alkyl sulfates; (d) polycarboxylates; and (e) at least one agrochemically acceptable excipient.

12. The composition of claim 13, wherein the alkyl sulfate and the polycarboxylate are present in a weight ratio of about 0.1:1 to about 10:

1.

13. A method for preparing a herbicidal composition, the method comprising: (a) mixing an aniline herbicide with a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersant and at least one agrochemically acceptable excipient to obtain a mixture; (b) grinding the mixture obtained in step (a); (c) preparing a dough using the mixture; (d) extruding the mass to obtain granules; as well as (e) drying the granules to obtain the herbicidal composition.

14. Use of a herbicidal composition for controlling weeds, the composition comprising: (a) Aniline herbicides; (b) pyrimidinylsulfonylurea herbicides; (c) at least one wetting agent; (d) at least one dispersant; and (e) at least one agrochemically acceptable excipient.

15. A method for controlling weeds by applying to a plant or its locus an effective amount of a herbicidal composition, the composition comprising: (a) Aniline herbicides; (b) pyrimidinylsulfonylurea herbicides; (c) at least one wetting agent; (d) at least one dispersant; and (e) at least one agrochemically acceptable excipient.

Images