Traditional Chinese medicine compound for promoting blood circulation to remove blood stasis, promoting qi circulation and dredging collaterals and suitable for rehabilitation of qi stagnation and blood stasis type diseases

Abstract

The invention provides a traditional Chinese medicine compound for promoting blood circulation to remove blood stasis, promoting qi circulation and dredging collaterals and suitable for rehabilitation of qi stagnation and blood stasis type diseases, and belongs to the technical field of traditional Chinese medicine rehabilitation treatment. The formula is prepared from radix clematidis, radix cyathulae, astragalus membranaceus, cassia twig, garden balsam stem, vinegar frankincense, vinegar myrrh, safflower carthamus, angelica sinensis, radix paeoniae rubra, erigeron breviscapus, golden cypress and rheum officinale. All the medicines are combined to achieve the effects of promoting blood circulation to remove blood stasis and promoting qi circulation to dredge collaterals. The traditional Chinese medicine composition has a clinical curative effect on various qi-stagnation and blood stasis type diseases, can improve the sleep quality of patients, has no adverse reaction, and is easier to accept by the patients compared with oral medicines. The traditional Chinese medicine compound for promoting blood circulation to remove blood stasis, promoting qi circulation and dredging collaterals has the effects of promoting blood circulation to remove blood stasis, promoting qi circulation and dredging collaterals, has a good curative effect on qi stagnation and blood stasis type diseases after being used for a long time, and can be widely used for treating various diseases in the rehabilitation department.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine rehabilitation therapy, and particularly relates to a traditional Chinese medicine compound for activating blood circulation to dissipate stasis and promoting qi circulation to dredge collaterals, which is applicable to the rehabilitation of diseases with qi stagnation and blood stasis syndrome. Background Art

[0002] Qi stagnation and blood stasis syndrome refers to the pathological state in which qi stagnation and blood stasis coexist. Generally, it is often caused by the unsmooth flow of qi in the human body first, and then the stasis of blood circulation. The main clinical manifestations are local distension or pain symptoms. Prolonged qi stagnation can cause blood stasis, forming qi stagnation and blood stasis, which intensifies the local pain. Due to the different causes of diseases, the same symptom can also be caused by different reasons. The diseases caused by qi stagnation and blood stasis are called diseases with qi stagnation and blood stasis syndrome, which widely exist in the follow-up diseases of the rehabilitation department of hospitals.

[0003] According to the syndrome differentiation and treatment of traditional Chinese medicine, for diseases with qi stagnation and blood stasis syndrome, selecting appropriate traditional Chinese medicine needs to achieve dredging collaterals, warming meridians to dredge collaterals, and dispelling cold and relieving pain, and can be widely used in the rehabilitation treatment of this disease. Traditional Chinese medicine foot bath, as one of the commonly used therapies in external treatment of traditional Chinese medicine, selects appropriate traditional Chinese medicine according to the syndrome differentiation and treatment of traditional Chinese medicine, decocts it in water and bathes the feet, which can stimulate acupoints, dredge collaterals, warm meridians to dredge collaterals, and dispel cold and relieve pain, and can be widely used in the treatment of diseases in the rehabilitation department. Summary of the Invention

[0004] The technical problem to be solved by the present invention is to provide a traditional Chinese medicine compound for activating blood circulation to dissipate stasis and promoting qi circulation to dredge collaterals, which is applicable to the rehabilitation of diseases with qi stagnation and blood stasis syndrome. The combination of various herbs can achieve the effects of activating blood circulation to dissipate stasis and promoting qi circulation to dredge collaterals, and cooperating with traditional Chinese medicine foot bath can have a good curative effect on various diseases in the rehabilitation department.

[0005] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0006] A traditional Chinese medicine compound for activating blood circulation to dissipate stasis and promoting qi circulation to dredge collaterals, which is applicable to the rehabilitation of diseases with qi stagnation and blood stasis syndrome. The traditional Chinese medicine compound is composed of the following traditional Chinese medicine raw materials by weight:

[0007] Clematis chinensis Osbeck 10 - 20 g, Cyathula officinalis Kuan 12 - 18 g, Astragalus membranaceus (Fisch.) Bunge 10 - 18 g, Cinnamomum cassia Presl 8 - 12 g, Speranskia tuberculata (Bunge) Baill. 5 - 15 g, Olibanum processed with vinegar 8 - 15 g, Myrrha processed with vinegar 5 - 10 g, Carthamus tinctorius L. 8 - 10 g, Angelica sinensis (Oliv.) Diels 6 - 12 g, Paeonia lactiflora Pall. 8 - 10 g, Erigeron breviscapus (Vant.) Hand.-Mazz. 1 - 5 g, Phellodendron amurense Rupr. 5 - 15 g, Rheum palmatum L. 5 - 10 g.

[0008] In this compound, Clematis chinensis Osbeck dispels wind-dampness and dredges collaterals, and is used for rheumatic arthralgia, limb numbness, muscle spasms, and limited flexion and extension.

[0009] Cyathula officinalis Kuan removes blood stasis and dredges meridians, promotes joint movement, and promotes diuresis and relieves stranguria. It is used for amenorrhea, abdominal mass, retention of the placenta, traumatic injury, rheumatic pain, foot tendon pain, hematuria, and stranguria with blood.

[0010] Astragalus membranaceus can replenish qi and lift yang, secure the exterior and stop sweating, promote diuresis and alleviate edema, generate body fluid and nourish blood, activate qi and promote blood circulation to relieve pain, expel toxins and discharge pus, and astringe sores and promote granulation. It is used for qi deficiency with weakness, poor appetite and loose stools, qi sinking, chronic diarrhea with rectal prolapse, hematochezia and metrorrhagia, spontaneous sweating due to exterior deficiency, qi deficiency edema, internal heat with thirst, sallow complexion due to blood deficiency, hemiplegia, pain and numbness in the bi syndrome, difficulty in ulceration of carbuncles and sores, and non-healing of sores for a long time.

[0011] Cinnamomum cassia can induce sweating and relieve the exterior syndrome, warm and dredge the meridians, promote yang qi transformation and qi movement, and calm the rebellious qi. It is used for wind-cold cold, cold pain in the epigastrium and abdomen, amenorrhea due to blood cold, arthralgia and pain in the joints, phlegm retention, edema, palpitation, and rushing of qi.

[0012] Speranskia tuberculata can soothe the muscles and tendons, activate blood circulation, reduce swelling and relieve pain. It is used for headache and deviation of the mouth and eyes caused by wind invading the meridians and stagnation of collaterals, or local swelling and pain, headache of the head and face, trigeminal neuralgia, facial nerve palsy, acute and chronic soft tissue injury caused by traumatic injury.

[0013] Olibanum processed with vinegar can activate blood circulation to relieve pain, reduce swelling and promote granulation. It is used for chest pain due to angina pectoris, epigastric pain, dysmenorrhea and amenorrhea, stasis after childbirth, abdominal pain due to mass, rheumatic arthralgia, contracture of tendons and vessels, traumatic injury, carbuncles and sores.

[0014] Myrrha processed with vinegar can disperse stasis to relieve pain, reduce swelling and promote granulation. It is used for chest pain due to angina pectoris, epigastric pain, dysmenorrhea and amenorrhea, stasis after childbirth, abdominal pain due to mass, rheumatic arthralgia, traumatic injury, carbuncles and sores.

[0015] Carthamus tinctorius can activate blood circulation to dredge the channels and disperse stasis to relieve pain. It is used for amenorrhea, dysmenorrhea, retention of lochia, mass, chest pain, abdominal pain due to qi stagnation, stabbing pain in the chest and hypochondrium, traumatic injury, swelling and pain of sores and ulcers.

[0016] Angelica sinensis can enrich blood and activate blood circulation, regulate menstruation and relieve pain, moisten the intestines and promote defecation. It is used for sallow complexion and lassitude due to blood deficiency, dizziness and palpitation, irregular menstruation, amenorrhea and dysmenorrhea, cold pain in the abdomen, rheumatic arthralgia, traumatic injury, carbuncles and sores, constipation due to intestinal dryness.

[0017] Paeonia lactiflora can clear heat and cool blood, disperse stasis and relieve pain. It is used for heat entering nutrient blood, epidemic febrile disease with maculae, hematemesis and epistaxis, redness and swelling pain of the eyes, hypochondriac pain due to liver depression, amenorrhea and dysmenorrhea, abdominal pain due to mass, traumatic injury, carbuncles and sores.

[0018] Erigeron breviscapus can activate blood circulation to dissipate stasis, dredge the channels and collaterals. It is used for stasis of cerebral collaterals, hemiplegia due to stroke, blockage of heart vessels, chest pain due to angina pectoris

[0019] Phellodendron amurense can clear heat and dry dampness, purge fire and reduce steaming, detoxify and treat sores. It is used for damp-heat diarrhea and dysentery, jaundice with red urine, leukorrhea with genital itching, painful urinary dysfunction, beriberi, bone-steaming fever, night sweating, spermatorrhea, sores and ulcers, eczema and dermatitis.

[0020] Rheum palmatum can promote defecation by purging, clear heat and purge fire, cool blood and detoxify, expel stasis and dredge menstruation, promote diuresis and relieve jaundice. It is used for constipation due to excess heat accumulation, hematemesis and epistaxis due to blood heat, redness and swelling pain of the eyes and throat, carbuncles and sores, appendicitis with abdominal pain, amenorrhea due to stasis, stasis after childbirth, traumatic injury, damp-heat dysentery, jaundice with red urine, stranguria syndrome, edema; for external use in treating burns and scalds.

[0021] This traditional Chinese medicine compound for promoting blood circulation to remove blood stasis and activating qi and dredging collaterals is formulated by combining herbs for dispelling wind and dampness, promoting blood circulation to remove blood stasis, and activating qi and relieving pain. Clematis chinensis and Cyathula officinalis are monarch herbs, which can dispel wind-dampness, dredge collaterals, remove blood stasis and dredge menstruation, promote joint movement, and promote diuresis. Astragalus membranaceus can tonify qi and boost yang, Cinnamomum cassia can warm and dredge the tendons and vessels, Speranskia tuberculata can dispel wind and dampness, and promote blood circulation to relieve pain. Olibanum and Myrrha can promote blood circulation, activate qi, and remove blood stasis, and they are ministerial herbs. Angelica sinensis, Paeonia lactiflora, Erigeron breviscapus, and Carthamus tinctorius can all promote blood circulation to remove blood stasis. Phellodendron amurense can clear damp-heat in the lower jiao, and Rheum palmatum can remove blood stasis and clear heat, and they are adjuvant herbs. When these herbs are used together, they can achieve the effects of promoting blood circulation to remove blood stasis and activating qi and dredging collaterals.

[0022] As a preferred technical solution of the present invention, the traditional Chinese medicine compound is composed of the following traditional Chinese medicine raw materials by weight:

[0023] Clematis chinensis 15g, Cyathula officinalis 15g, Astragalus membranaceus 15g, Cinnamomum cassia 10g, Speranskia tuberculata 10g, Olibanum 10g, Myrrha 10g, Carthamus tinctorius 10g, Angelica sinensis 10g, Paeonia lactiflora 10g, Erigeron breviscapus 2g, Phellodendron amurense 10g, Rheum palmatum 10g.

[0024] Put all the herbs into a non-woven fabric and seal it, then put it into a container, add water and boil it to obtain a fumigation and washing liquid. First, fumigate the feet and then soak the feet. Or, add water and boil it to obtain a fumigation and washing liquid, let it cool, adjust the temperature with boiling water before use, and first fumigate the feet and then soak the feet.

[0025] Clinical pharmacists of traditional Chinese medicine assisted the physicians in the rehabilitation department to formulate the foot bath prescription of this traditional Chinese medicine for promoting blood circulation to remove blood stasis and activating qi and dredging collaterals (Jinzu Powder) and used it clinically. Clinical pharmacists of traditional Chinese medicine conducted full-course pharmaceutical care for 56 patients using it clinically, observed the clinical situation, and conducted a pharmaceutical evaluation study on its clinical efficacy.

[0026] Clinical experiments have shown that: The formulation of Jinzu Powder is reasonable, and it has clinical efficacy for various diseases of qi stagnation and blood stasis type. At the same time, it can improve the sleep quality of patients, has no adverse reactions, and is more acceptable to patients compared with oral medications. Jinzu Powder has efficacy for various diseases in the rehabilitation department, has the functions of promoting blood circulation to remove blood stasis and activating qi and dredging collaterals. Long-term use has good efficacy for diseases of qi stagnation and blood stasis type, and it can be widely used for the treatment of various diseases in the rehabilitation department and is worthy of promotion. Specific implementation mode

[0027] To study the clinical efficacy of the traditional Chinese medicine for promoting blood circulation to remove blood stasis and activating qi and dredging collaterals (Jinzu Powder), clinical pharmacists of traditional Chinese medicine participated in the clinical medication of patients throughout the process. To facilitate the use of Jinzu Powder by patients during hospitalization, the traditional Chinese medicine pharmacy of the hospital decocted Jinzu Powder on behalf of patients. The single-dose prescription is: Clematis chinensis 15g, Cyathula officinalis 15g, Astragalus membranaceus 15g, Cinnamomum cassia 10g, Speranskia tuberculata 10g, Olibanum 10g, Myrrha 10g, Carthamus tinctorius 10g, Angelica sinensis 10g, Paeonia lactiflora 10g, Erigeron breviscapus 2g, Phellodendron amurense 10g, Rheum palmatum 10g. When using, add boiling water to make it hot, soak the feet once in the morning and once in the evening, use 1 dose each time, and 7 days is a course of treatment.

[0028] For the clinical pharmacodynamic study of Jinzu Powder, a retrospective analysis was carried out on 56 patients who used Jinzu Powder. The Excel software was used to collect the basic information (gender, age), clinical diagnosis, dosage of Jinzu Powder, clinical efficacy, etc. of the patients and summarize and analyze them.

[0029] 1 Basic information of patients

[0030] The basic information of 56 patients who used Jinzu Powder is shown in Table 1 below.

[0031] Table 1 Basic information of patients

[0032]

[0033] 2 Clinical diagnosis

[0034] The clinical diagnoses of the 56 patients collected were statistically analyzed, and the specific situation is shown in Table 2 below.

[0035] Table 2 Clinical diagnosis of patients

[0036]

[0037] 3 Dosage of Jinzu Powder used by patients

[0038] The dosage of the medicine used by the patients was analyzed, and the specific situation is shown in Table 3 below.

[0039] Table 3 Medication situation of patients

[0040]

[0041] 4 Comparison of symptoms and efficacy before and after treatment of patients

[0042] The pain scores and sleep quality of the patients before and after treatment were compared and analyzed. The visual analogue scale (VAS) was used to evaluate the pain degree. The patient marked the pain degree on a scale from zero to ten. 0 points indicated no pain, and 10 points indicated the most severe pain. The higher the score, the more severe the pain. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the sleep quality, using an integral system. The score was inversely proportional to the sleep quality. The higher the PSQI score, the worse the sleep quality. Taking the average values of the patients' VAS and PSQI scores as a reference, the specific situation is shown in the following table.

[0043] Table 4 Symptoms and efficacy before and after treatment of patients

[0044]

[0045] 5 Pharmaceutical care and pharmaceutical evaluation of the clinical use of Jinzu Powder

[0046] To observe the reactions of patients during the clinical use of Jinzu Powder, clinical pharmacists of traditional Chinese medicine participated in clinical treatment throughout the process, provided full-course pharmaceutical care for patients, monitored the key points of use, enhanced patients' compliance, and answered patients' questions. After clinical observation, no adverse reactions were found in patients after using it. At the same time, some patients reported that using Jinzu Powder for foot bath helped with sleep function, could also improve anxiety, and had the functions of reducing inflammation, swelling, and pain for patients with limb swelling who had cardiovascular and cerebrovascular diseases.

[0047] Since more than 70% of the patients using Jinzu Powder clinically are in the recovery period of brain and blood vessel diseases, the limb sensory nerves of such patients are not sensitive. When soaking feet, the water temperature can be adjusted to about 50°C. It can be found from the clinical efficacy observation of 56 patients that Jinzu Powder has good clinical efficacy.

[0048] Clinical pharmacists of traditional Chinese medicine participated in clinical pharmaceutical services of traditional Chinese medicine throughout the process. From the formulation of prescriptions to the clinical efficacy observation, it can effectively enhance the clinical status of pharmaceutical staff in the hospital and gain the respect of patients at the same time. Through clinical experiments, this invention has determined that Jinzu Powder has good curative effects on various diseases in the rehabilitation department. This compound has the effects of promoting blood circulation to remove blood stasis and promoting qi movement to dredge collaterals. Long-term use has good curative effects on diseases of qi stagnation and blood stasis type and can be widely used in the treatment of various diseases in the rehabilitation department and is worthy of promotion.

[0049] The above content is only an example and explanation of the concept of this invention. Those skilled in the art of this technology can make various modifications, supplements, or use similar methods to replace the specific embodiments described as long as they do not deviate from the concept of the invention or exceed the scope defined by this claim book, and they should all belong to the protection scope of this invention.

Claims

1. A traditional Chinese medicine compound for promoting blood circulation to remove blood stasis and activating qi flow to dredge collaterals, which is applicable to the rehabilitation of diseases of qi stagnation and blood stasis type, characterized in that, The traditional Chinese medicine compound is composed of traditional Chinese medicine raw materials with the following weights: Clematis chinensis Osbeck 10 - 20 g, Cyathula officinalis Kuan 12 - 18 g, Astragalus membranaceus (Fisch.) Bunge 10 - 18 g, Cinnamomum cassia Presl 8 - 12 g, Speranskia tuberculata (Bunge) Baill. 5 - 15 g, Olibanum 8 - 15 g, Myrrha 5 - 10 g, Carthamus tinctorius L. 8 - 10 g, Angelica sinensis (Oliv.) Diels 6 - 12 g, Paeonia lactiflora Pall. 8 - 10 g, Erigeron breviscapus (Vant.) Hand.-Mazz. 1 - 5 g, Phellodendron amurense Rupr. 5 - 15 g, Rheum officinale Baill. 5 - 10 g.

2. The traditional Chinese medicine compound for activating blood circulation to dissipate stasis and promoting qi movement to dredge collaterals according to claim 1, wherein, The traditional Chinese medicine compound is composed of traditional Chinese medicine raw materials with the following weights: Clematis chinensis Osbeck 15 g, Cyathula officinalis Kuan 15 g, Astragalus membranaceus (Fisch.) Bunge 15 g, Cinnamomum cassia Presl 10 g, Speranskia tuberculata (Bunge) Baill. 10 g, Olibanum 10 g, Myrrha 10 g, Carthamus tinctorius L. 10 g, Angelica sinensis (Oliv.) Diels 10 g, Paeonia lactiflora Pall. 10 g, Erigeron breviscapus (Vant.) Hand.-Mazz. 2 g, Phellodendron amurense Rupr. 10 g, Rheum officinale Baill. 10 g.

3. A method for preparing the traditional Chinese medicine compound for activating blood circulation to dissipate stasis and promoting qi flow to dredge collaterals as claimed in claim 1 or 2, characterized in that, Put all the medicinal materials together into a non-woven fabric bag and seal it, then put it into a container, add water and boil it to obtain a fumigating and washing liquid, which is used for foot fumigation first and then foot soaking.

4. A method for preparing the traditional Chinese medicine compound for promoting blood circulation to remove blood stasis and activating qi to dredge collaterals as described in claim 1 or 2, characterized in that, Put all the medicinal materials together into a non-woven fabric bag and seal it, then put it into a container, add water and boil it to obtain a fumigating and washing liquid. Let it cool down, adjust the temperature with boiling water before use, and use it for foot fumigation first and then foot soaking.

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