Biological sample storage device and biological sample cryopreservation frame thereof

Abstract

The invention provides a biological sample storage device and a biological sample cryopreservation rack thereof, and the biological sample cryopreservation rack comprises a main body, the main body comprises a back plate, and the back plate is provided with at least one mounting part; each partition piece is detachably fixed to the mounting part, and at least two adjacent partition pieces and the back plate jointly form a sub containing cavity used for containing biological samples. According to the biological sample storage device and the biological sample cryopreservation frame thereof, the partition pieces are detachable relative to the back plate, so that when a certain partition piece is damaged, only the partition piece needs to be detached, replaced or maintained, the maintenance is convenient, and the maintenance cost is low. Moreover, the separator can be produced in a mold opening manner, so that the process and production cost is reduced.

Description

Technical Field

[0001] The present application relates to the technical field of biological sample storage, and particularly to a biological sample storage device and a biological sample freezing rack thereof. Background Art

[0002] With the rapid development of the biomedical industry, large-scale biological sample banks have emerged, and the storage volume of biological samples has become larger and larger. Generally, biological samples such as tissues and cells in clinics or laboratories are stored in a biological sample storage device that uses cold energy to store biological samples. The biological sample storage device stores biological samples through a biological sample freezing rack, and the biological sample freezing rack has a partition member. The partition member divides the accommodation cavity of the biological sample freezing rack into multiple sub-accommodation cavities, and each sub-accommodation cavity is used to accommodate biological samples. However, the main body and the partition member of this biological sample freezing rack are integrated, which is not convenient for maintenance and replacement. Summary of the Invention

[0003] In view of the above problems, the present application is proposed to provide a biological sample storage device and a biological sample freezing rack thereof that overcome the above problems or at least partially solve the above problems.

[0004] The present application first provides a biological sample freezing rack, including: a main body, the main body includes a back plate, and at least one installation portion is provided on the back plate; at least one partition member, each partition member is detachably fixed to the installation portion, and at least two adjacent partition members and the back plate together form a sub-accommodation cavity for placing biological samples.

[0005] Optionally, the at least one installation portion is a plurality of installation portions, the plurality of installation portions include a first part and a second part, the first part includes a plurality of the installation portions, the second part includes a plurality of the installation portions, and the size of the sub-accommodation cavity formed when the partition member is fixed to the first part is different from the size of the sub-accommodation cavity formed when the partition member is fixed to the second part.

[0006] Optionally, the main body defines an accommodation cavity, and the partition member is disposed in the accommodation cavity.

[0007] Optionally, the main body further includes at least one side plate, and each side plate extends forward from one end of the back plate.

[0008] Optionally, at least one of the partition members includes: a first mounting plate, the first mounting plate is detachably fixed to the back plate; a first support plate, the first support plate extends forward from the lower end of the first mounting plate, and the first support plate is used to support the corresponding biological sample.

[0009] Optionally, the at least one separator further includes: a partition board, which is fixed to the first support board to divide the first support board into a first sub-board located in the first sub-accommodation cavity and supporting a first biological sample, and a second sub-board located in the second sub-accommodation cavity and supporting a second biological sample.

[0010] Optionally, at least one of the separators includes: a second mounting board, which is detachably fixed to the side board; a second support board, which extends from the lower end of the second mounting board in the direction towards the accommodation cavity, and the second support board is used to support the corresponding biological sample.

[0011] Optionally, the at least one side board includes a first side board and a second side board, and the first side board and the second side board respectively extend forward from the transverse two ends or the longitudinal two ends of the back board.

[0012] Optionally, the separator is detachably fixed to the back board by means of threading and / or plugging.

[0013] Optionally, at least some of the plurality of sub-accommodation cavities are arranged along a first direction, and at least some other part is arranged along a second direction different from the first direction.

[0014] This application also provides a biological sample storage device, including: a box body, which is provided with a storage cavity; any one of the above-mentioned biological sample freezing racks, and the biological sample freezing rack is arranged in the storage cavity.

[0015] Optionally, the biological sample storage device further includes: a fixing device, which is arranged in the storage cavity and fixed to the box body, and each biological sample freezing rack is fixed to the fixing device so that the relative position of each sub-accommodation cavity and the fixing device is fixed; a driving device, which is arranged in the storage cavity, the driving device is connected to a picking and placing device to drive the picking and placing device to move, so as to pick and place the biological samples stored in the biological sample freezing rack, and the driving device is fixed to the fixing device so that the relative position of the driving device and the fixing device is fixed.

[0016] The separator of the biological sample storage device and its biological sample freezing rack provided by this application is detachable relative to the back board. Therefore, when a certain separator is damaged, only this separator needs to be removed and replaced or repaired, which is convenient for maintenance and has a low maintenance cost. Moreover, such a separator can also be produced by means of mold opening, reducing the process and production costs. Description of the Drawings

[0017] Through the description of this application with reference to the drawings in the following text, other objects and advantages of this application will be obvious and can help to have a comprehensive understanding of this application.

[0018] Figure 1 is a schematic structural view of a biological sample freezing rack according to some embodiments of the present application; Figure 2 is a schematic structural view of a partition of a biological sample freezing rack according to some embodiments of the present application; Figure 3 is a schematic structural view of a partition of a biological sample freezing rack according to some other embodiments of the present application.

[0019] In the figure, there is a biological sample freezing rack 300, a main body 310, a back plate 311, side plates 312, a partition 320, a first mounting plate 321, a first support plate 322, a partition board 323, a second mounting plate 324, a second support plate 325, a first reinforcing plate 330, and a second reinforcing plate 340. Detailed Embodiments

[0020] To make the objectives, technical solutions, and advantages of the present application clearer, the technical solutions of the present application will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present application. Apparently, the described embodiments are only one embodiment of the present application, rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art without creative efforts based on the described embodiments of the present application fall within the scope of protection of the present application.

[0021] Unless otherwise defined, the technical terms or scientific terms used in the present application shall have the ordinary meanings understood by those of ordinary skill in the art to which the present application pertains.

[0022] This embodiment first provides a biological sample freezing rack 300, Figure 1 is a schematic structural view of a biological sample freezing rack 300 according to some embodiments of the present application, Figure 2 is a schematic structural view of a partition 320 of a biological sample freezing rack 300 according to some embodiments of the present application, Figure 3 is a schematic structural view of a partition 320 of a biological sample freezing rack 300 according to some other embodiments of the present application.

[0023] The biological sample freezing rack 300 includes a main body 310 and at least one partition 320. The main body 310 includes a back plate 311, and the back plate 311 is provided with at least one mounting portion. Each partition 320 is detachably fixed to the mounting portion, and at least two adjacent partitions 320 and the back plate 311 together form a sub-accommodation cavity for placing biological samples.

[0024] The partition 320 of this biological sample freezing rack 300 is detachable relative to the back plate 311. Thus, when a certain partition 320 is damaged, only this partition 320 needs to be removed and replaced or repaired, which is convenient for maintenance and has a low maintenance cost. Moreover, this partition 320 can also be produced by mold opening, reducing the process and production costs.

[0025] In some embodiments, the at least one mounting portion is a plurality of mounting portions, and the plurality of mounting portions include a first part and a second part. The first part includes a plurality of the mounting portions, and the second part includes a plurality of the mounting portions. The size of the sub-accommodation cavity formed when the partition 320 is fixed to the first part is different from the size of the sub-accommodation cavity formed when the partition 320 is fixed to the second part. For example, the mounting portions are mounting holes, and these mounting holes are divided into a first mounting hole group and a second mounting hole group. When the partition is mounted on the first mounting hole group, the formed sub-accommodation cavity can accommodate a freezing box of a first size, and when the partition is mounted on the second mounting hole group, the formed sub-accommodation cavity can accommodate a freezing box of a second size.

[0026] That is to say, the sub-accommodation cavity formed by the first part and the sub-accommodation cavity formed by the second part can respectively accommodate biological samples of different sizes. Specifically, the biological sample can be placed in a freezing tube, and the freezing tube is placed in a freezing box. The sub-accommodation cavity is used to accommodate the biological sample by accommodating the freezing box. That is, this biological sample freezing rack 300 can be adapted to freezing boxes of different sizes, improving its applicability. Specifically, the distance between two adjacent mounting portions in the first part and the second part is different, such as the horizontal (left-right direction) distance or the height direction distance is different, etc.

[0027] Among them, the main body 310 defines an accommodation cavity, and the partition 320 is arranged in the accommodation cavity. For example, the main body 310 can be hemispherical, cubic, etc. This main body 310 has a large space utilization rate, has many parts where it can be installed, and is convenient for installation. In other embodiments, the main body 310 may only include the back plate 311, so that the structure is simple and the weight is small.

[0028] In some embodiments, the main body 310 further includes at least one side plate 312, and each side plate 312 extends forward from one end of the back plate 311. This main body 310 has a large space utilization rate, has many parts where it can be installed, and is convenient for installation. Preferably, the at least one side plate 312 includes a first side plate 312 and a second side plate 312, and the first side plate 312 and the second side plate 312 respectively extend forward from the transverse two ends or the longitudinal two ends of the back plate 311. Among them, the at least one side plate 312 may include four side plates 312, and the four side plates 312 respectively extend forward from the transverse two ends and the longitudinal two ends.

[0029] At least one separator 320 may include a first mounting plate 321 and a first support plate 322. The first mounting plate 321 is detachably fixed to the back plate 311; the first support plate 322 extends forward from the lower end of the first mounting plate 321, and the first support plate 322 is used to support the corresponding biological sample. The at least one separator 320 may further include a partition plate 323, and the partition plate 323 is fixed to the first support plate 322 to divide the first support plate 322 into a first sub-plate located in the first sub-accommodation cavity and supporting the first biological sample, and a second sub-plate located in the second sub-accommodation cavity and supporting the second biological sample. The first support plate 322 can support two biological samples simultaneously, and can separate the biological samples in the corresponding sub-accommodation cavities, having a certain limiting effect.

[0030] In some embodiments, the side plate 312 may have a protrusion, and the protrusion can jointly support the biological sample with the adjacent separator 320. Thus, the storage capacity of the biological sample storage rack 300 having the side plate 312 is improved. In other embodiments, at least one separator 320 may include a second mounting plate 324 and a second support plate 325. The second mounting plate 324 is detachably fixed to the side plate 312; the second support plate 325 extends from the lower end of the second mounting plate 324 in the direction towards the accommodation cavity, and the second support plate 325 is used to support the corresponding biological sample. Thus, the storage capacity of the biological sample storage rack 300 having the side plate 312 is improved, and further, the biological sample storage rack 300 is convenient for maintenance and has a low maintenance cost.

[0031] In some embodiments, the separator 320 is detachably fixed to the back plate 311 by means of threading and / or plugging. Preferably, the separator 320 is detachably fixed to the back plate 311 by means of threading and plugging. Thus, the separator 320 is first plugged into the back plate 311 and then fixed by threading. Thus, when fixing by threading, there is no need to fix the separator 320 manually or by other means, and the operation is convenient.

[0032] The biological sample storage rack 300 includes a main body 310 and at least one separator 320. The main body 310 is integrally formed, and the main body 310 defines an accommodation cavity. Each separator 320 is disposed in the accommodation cavity, and each separator 320 is fixed to the main body 310 to divide the accommodation cavity into a plurality of sub-accommodation cavities, and each sub-accommodation cavity is used to accommodate a biological sample. At least part of the plurality of sub-accommodation cavities are arranged along a first direction, and at least another part is arranged along a second direction different from the first direction.

[0033] The biological sample storage rack 300 provided in this embodiment is integrally formed with the main body 310 of the biological sample storage rack 300. Therefore, processes such as welding are not required, avoiding situations where the shape, size, etc. of the biological sample storage rack 300 have large deviations during manual welding and other processes. This enables the biological sample storage device and its biological sample storage rack 300 to pick and place the biological samples stored in the biological sample storage rack 300 more accurately when using automated equipment, reduces the processes, and lowers the cost.

[0034] It can be understood that when the biological sample storage rack 300 is a metal part, it can be integrally formed by folding, bending, direct casting, etc. When the biological sample storage rack 300 is a plastic part, it can be formed by integral injection molding, etc. This embodiment does not limit the material and forming method of the biological sample storage rack 300.

[0035] At least some of the multiple sub-accommodation cavities are arranged along a first direction, and at least another part is arranged along a second direction different from the first direction. Thereby, the accommodation cavity can accommodate more biological samples. It can be understood that the size of such a biological sample storage rack 300 is relatively large. If the integral forming method is not adopted, the errors in size and position will be greater. Among them, the biological samples can be stored in the accommodation cavity in the form of cryotubes, cryobags, etc. The cryotubes and cryobags can be stored in a cryobox.

[0036] In some embodiments, the first direction includes a transverse direction and / or the second direction includes a longitudinal direction. Thus, it is beneficial to improve the space utilization rate, and the arrangement of the sub-accommodation cavities is more regular, making it more suitable for a biological sample storage device with a square overall shape.

[0037] Among them, the main body 310 may include a back plate 311 and at least one side plate 312. Each side plate 312 extends forward from one end of the back plate 311. Thus, the structure of the main body 310 is simple and has strong stability.

[0038] In some embodiments, the at least one side plate 312 includes a first side plate 312 and a second side plate 312. The first side plate 312 and the second side plate 312 respectively extend forward from the transverse two ends or longitudinal two ends of the back plate 311. Thus, it is more convenient for the installation and positioning of the main body 310. In some embodiments, the first side plate 312 and the second side plate 312 respectively extend towards each other from the transverse two ends of the back plate 311, and the at least one side plate 312 includes a third side plate 312 and a fourth side plate 312. The third side plate 312 and the fourth side plate 312 respectively extend towards each other from the longitudinal two ends of the back plate 311.

[0039] The biological sample freezing rack 300 may further include at least one first reinforcing plate 330, and each first reinforcing plate 330 is connected to the first side plate 312 and the second side plate 312. Thus, the relative positions of the first side plate 312 and the second side plate 312 are stabilized and not prone to displacement, which is beneficial to automated operation.

[0040] Preferably, at least one of the first reinforcing plates 330 is further connected to the back plate 311. Thus, the relative positions of the first side plate 312, the second side plate 312, and the back plate 311 are stabilized and not prone to displacement, which is beneficial to automated operation.

[0041] The biological sample freezing rack 300 may further include at least one second reinforcing plate 340, and each second reinforcing plate 340 is connected to the side plate 312 through a plurality of connection positions. Thus, the side plate 312 is not prone to deformation, which is beneficial to automated operation.

[0042] In some embodiments, at least one partition 320 is detachably mounted on the main body 310. Thus, operations such as maintenance of the partition 320 are facilitated. The detachable function can be achieved by means of threads, rivets, hooks, plug-ins, snaps, etc. Specifically, hooks (the main body is provided with an opening and the partition is hung on the opening) and other methods (such as rivets) can be used simultaneously, which can increase the stability of the partition 320 and the main body 310, prevent the failure of other structures such as rivets under low-temperature conditions, and avoid the partition 320 falling off due to a collision.

[0043] This embodiment also provides a biological sample storage device, which includes a box body and a biological sample freezing rack 300. The box body is provided with a storage cavity, and the biological sample freezing rack 300 is arranged in the storage cavity.

[0044] The biological sample storage device may further include a fixing device and a driving device. The fixing device is arranged in the storage cavity and fixed to the box body, and each biological sample freezing rack 300 is fixed to the fixing device so that the relative position of each sub-accommodation cavity and the fixing device is fixed. The driving device is arranged in the storage cavity, and the driving device is connected to a picking and placing device to drive the picking and placing device to move, so as to pick and place the biological samples stored in the biological sample freezing rack 300. The driving device is fixed to the fixing device so that the relative position of the driving device and the fixing device is fixed.

[0045] Among them, the shape, structure, etc. of the fixing device in this embodiment are not limited. For example, it can be in the shape of a plate or a frame structure. The biological sample freezing rack 300 and the driving device of this biological sample storage device are both based on the fixing device as a positioning reference, so that the relative position relationship between the freezing rack and the driving device is relatively fixed, and thus the problem of inaccurate picking and placing positions is not likely to occur.

[0046] For the embodiments of the present application, it should also be noted that, without conflict, the embodiments of the present application and the features in the embodiments can be combined with each other to obtain new embodiments.

[0047] The above is only the specific implementation manner of the present application, but the protection scope of the present application is not limited thereto. The protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A biological sample freezing rack, characterized in that, Comprising: A main body, the main body including a back plate, and at least one mounting portion being provided on the back plate; At least one partition member, each partition member being detachably fixed to the mounting portion, and at least two adjacent partition members and the back plate jointly forming a sub-accommodation cavity for placing biological samples.

2. The biological sample freezing rack according to claim 1, wherein The at least one mounting portion is a plurality of mounting portions, the plurality of mounting portions including a first portion and a second portion, the first portion including a plurality of the mounting portions, the second portion including a plurality of the mounting portions, and the size of the sub-accommodation cavity formed when the partition member is fixed to the first portion being different from the size of the sub-accommodation cavity formed when the partition member is fixed to the second portion.

3. The biological sample freezing rack according to claim 1, wherein The main body defines an accommodation cavity, and the partition member is disposed in the accommodation cavity.

4. The biological sample freezing rack according to claim 3, characterized in that, The main body further includes at least one side plate, and each side plate extends forward from one end of the back plate.

5. The biological sample freezing rack according to claim 4, wherein, At least one of the partition members includes: A first mounting plate, the first mounting plate being detachably fixed to the back plate; A first support plate, the first support plate extending forward from the lower end of the first mounting plate, and the first support plate being used for supporting the corresponding biological sample.

6. The biological sample freezing rack according to claim 5, wherein, The at least one of the partition members further includes: A partition plate, the partition plate being fixed to the first support plate to divide the first support plate into a first sub-plate located in a first sub-accommodation cavity and supporting a first biological sample, and a second sub-plate located in a second sub-accommodation cavity and supporting a second biological sample.

7. The cryopreservation rack for biological samples according to claim 4, wherein At least one of the partition members includes: A second mounting plate, the second mounting plate being detachably fixed to the side plate; A second support plate, the second support plate extending in a direction towards the accommodation cavity from the lower end of the second mounting plate, and the second support plate being used for supporting the corresponding biological sample.

8. The cryopreservation rack for biological samples according to claim 4, wherein, The at least one side plate includes a first side plate and a second side plate, and the first side plate and the second side plate respectively extend forward from the transverse two ends or the longitudinal two ends of the back plate.

9. The biological sample freezing rack according to claim 1, wherein The partition member is detachably fixed to the back plate by means of threading and / or plugging.

10. The biological sample freezing rack according to claim 1, wherein At least some of the plurality of sub-accommodation cavities are arranged along a first direction, and at least another part is arranged along a second direction different from the first direction.

11. A biological sample storage device, characterized in that, Comprising: A box body, the box body being provided with a storage cavity; The biological sample freezing rack according to any one of claims 1 to 10, the biological sample freezing rack being disposed in the storage cavity.

12. The biological sample storage device according to claim 11, wherein Further comprising: A fixing device, disposed in the storage cavity and fixed to the box body, and each biological sample freezing rack being fixed to the fixing device so that the relative position of each sub-accommodation cavity and the fixing device is fixed; A driving device, which is arranged in the storage cavity. The driving device is connected to a picking and placing device to drive the picking and placing device to move, so as to pick and place the biological samples stored in the biological sample storage rack. The driving device is fixed to the fixing device so that the relative positions of the driving device and the fixing device are fixed.

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