Sustained-release administration transnasal endoscopic postoperative conformal sphenoid sinus stent

Abstract

The invention relates to the technical field of medical instruments, and discloses a slow-release administration transnasal endoscopic postoperative conformal sphenoid sinus stent which comprises an elastic sleeve and a liquid outlet ball, a net rack is fixedly connected to the outside of the elastic sleeve, an arc-shaped medicine storage tube is arranged at the top end of the net rack, a plurality of oval tubes are fixedly connected to the outside of the net rack, and the oval tubes are arranged at the top end of the net rack. A liquid inlet is formed in the side, close to the elastic sleeve, of the oval pipe, first elastic pieces are fixedly connected to the left side and the right side of the interior of the oval pipe, second elastic pieces are fixedly connected to the side, close to the elastic sleeve, of the oval pipe, and a supporting assembly used for fixing the elastic sleeve is fixedly connected to the top end of the interior of the elastic sleeve. According to the device, a polyp is driven by air flow to extrude the net rack liquid outlet ball, so that the medicine is uniformly administrated, the bracket is supported in the sphenoid sinus cavity in cooperation with the rotating rod, the net rack is effectively prevented from shifting, and uniform distribution of various medicines is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a conformable sphenoid sinus stent for sustained-release drug administration after transnasal endoscopic surgery. Background Art

[0002] As an important anatomical structure deep in the nasal cavity, the sphenoid sinus is closely adjacent to multiple important organs and tissues around it, such as the optic nerve, cavernous sinus, etc. Lesions of the sphenoid sinus, such as sphenoid sinusitis, sphenoid sinus cysts, sphenoid sinus tumors, etc., will cause a series of serious symptoms, such as headache, visual impairment, hyposmia, etc., seriously affecting the quality of life of patients.

[0003] According to the search, the Chinese patent document, publication number: CN116019985A, discloses a nasal sinus drug-loaded stent and its preparation method; the nasal sinus drug-loaded stent includes: a stent body and a coating structure provided on the surface of the stent body; the stent body is a hollow cylindrical structure with openings at both ends, and the stent body is integrally woven by memory metal wires; the coating structure includes: a transition layer and a plurality of drug release layers sequentially stacked on the transition layer; the transition layer is provided on the surface of the stent body for connecting the stent body and the drug release layer; the material of the drug release layer includes a drug carrier, a therapeutic drug, and a cross-linking agent. The nasal sinus stent designed by the present invention solves the problem of the influence of the bonding or welding at the intersection points of the existing products on the mechanical properties of the stent. The stent of the present invention adopts an integral molding process, and there are no intersection points during the weaving process, avoiding the influence of the previous bonding or welding method on the mechanical properties of the stent. However, the above stent cannot store multiple drugs, cannot solve other possible symptoms of patients after FESS, and there are also problems such as small drug loading capacity, uncontrollable drug release, and poor treatment effect. Summary of the Invention

[0004] The purpose of the present invention is to provide a conformable sphenoid sinus stent for sustained-release drug administration after transnasal endoscopic surgery to solve the problems raised in the above background art.

[0005] To achieve the above purpose, the present invention adopts the following technical solution: A conformable sphenoid sinus stent for sustained-release drug administration includes an elastic sleeve and a liquid outlet ball. A grid is fixedly connected to the outside of the elastic sleeve. An arc-shaped medicine storage tube is arranged at the top of the grid. A plurality of elliptical tubes are fixedly connected to the outside of the grid. A liquid inlet is opened on one side of the elliptical tube close to the elastic sleeve. First elastic sheets are fixedly connected to both the left and right sides inside the elliptical tube. A second elastic sheet is fixedly connected to the side of the elliptical tube close to the elastic sleeve. A support assembly for fixing the elastic sleeve is fixedly connected to the top inside the elastic sleeve.

[0006] As a further description of the above technical solution:

[0007] The support assembly includes a plurality of positioning blocks. The outside of the positioning blocks is fixedly connected to the inner wall top end of the elastic sleeve. The outside of the positioning blocks is rotatably connected to a first connecting rod. The inner top end of the first connecting rod is rotatably connected to a first connecting block. The bottom end of the first connecting block is fixedly connected to a first magnetic block. The bottom end of the first magnetic block is fixedly connected to an elastic tube.

[0008] As a further description of the above technical solution:

[0009] The middle of the first connecting rod is rotatably connected to a second connecting rod. The adjacent ends of the second connecting rod are rotatably connected to a second connecting block. The top end of the second connecting block is fixedly connected to a second magnetic block. A card slot is formed in the middle of the second magnetic block.

[0010] As a further description of the above technical solution:

[0011] A medicine - carrying groove is formed inside the arc - shaped medicine - storing tube. The outside of the liquid - discharging ball is movably connected to the outside of the first elastic sheet.

[0012] As a further description of the above technical solution:

[0013] The top end of the elastic tube is fixedly connected to the inner wall of the card slot. The top end of is detachably connected to the top end of the second magnetic block.

[0014] As a further description of the above technical solution:

[0015] The outside of the liquid - discharging ball is movably connected to the front end of the second elastic sheet. A plurality of ball grooves are formed on the outside of the liquid - discharging ball.

[0016] As a further description of the above technical solution:

[0017] A first movable groove is formed on the outside of the first connecting block. The top end of the first connecting rod is rotatably connected to the inner wall of the first movable groove.

[0018] As a further description of the above technical solution:

[0019] A plurality of second movable grooves are formed on the outside of the second connecting block. The top end of the second connecting rod is rotatably connected to the inner wall of the second movable groove.

[0020] The present invention has the following beneficial effects:

[0021] 1. In the present invention, the arc - shaped medicine - storing tube of the sphenoid sinus stent contains a variety of drugs, and a plurality of liquid - discharging balls are arranged at the intersections of the stent. When the patient breathes, the airflow drives the polyp to squeeze the wire mesh frame, causing the liquid - discharging balls to rotate in the elliptical tube, promoting the outflow of the drugs in the arc - shaped medicine - storing tube along the liquid - discharging balls. This helps the drugs to be evenly distributed, improves the bioavailability, effectively relieves various postoperative symptoms, and enhances the treatment effect.

[0022] 2. In the present invention, the balloon delivery rod is inserted into the sphenoid sinus stent, and the external air pressure is inflated to make the head of the balloon squeeze and drive the second connecting block to move and adsorb towards the first connecting block. Finally, the second connecting rod supports the unfolding of the second connecting block, so that the stent is fixed in a cylindrical shape in the sphenoid sinus cavity, effectively preventing displacement and ensuring that the liquid outlet ball of the stent contacts the polyp position in the sphenoid sinus cavity. Description of the Drawings

[0023] Figure 1 It is a three-dimensional schematic diagram of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0024] Figure 2 It is a structural schematic diagram of an elastic sleeve of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0025] Figure 3 It is a structural schematic diagram of a wire mesh of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0026] Figure 4 It is a structural schematic diagram of an arc-shaped drug storage tube of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0027] Figure 5 It is a structural schematic diagram of an elliptical tube of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0028] Figure 6 It is a structural schematic diagram of a ball groove of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0029] Figure 7 It is a structural schematic diagram of a first connecting rod of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention;

[0030] Figure 8 It is a structural schematic diagram of a second connecting block of a conformable sphenoid sinus stent for sustained-release drug delivery after transnasal endoscopic surgery proposed by the present invention.

[0031] Legend Explanation:

[0032] 1. Elastic sleeve; 2. Wire mesh; 3. Arc-shaped drug storage tube; 4. Drug-carrying groove; 5. Elliptical tube; 6. Liquid inlet; 7. First elastic sheet; 8. Second elastic sheet; 9. Liquid outlet ball; 10. Ball groove; 11. Positioning block; 12. First connecting rod; 13. First connecting block; 14. First moving groove; 15. First magnet; 16. Elastic tube; 17. Second connecting rod; 18. Second connecting block; 19. Second moving groove; 20. Second magnet; 21. Card slot. Detailed Implementation Modes

[0033] Next, in combination with the accompanying drawings in the embodiments of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0034] Refer to Figures 1 to 3 , an embodiment provided by the present invention: a conformable sphenoid sinus stent for sustained-release drug administration after nasal endoscopy, including an elastic sleeve 1 and a liquid outlet ball 9. A wire frame 2 is fixedly connected to the outside of the elastic sleeve 1, and the wire frame 2 is a filamentous object. An arc-shaped medicine storage tube 3 is arranged at the top of the wire frame 2. The first drug is a glucocorticoid drug. There are eight arc-shaped medicine storage tubes 3. Anti-inflammatory drugs, decongestants and other drugs can be injected into the arc-shaped medicine storage tube 3 through a drug loading groove 4 and stored in the arc-shaped medicine storage tube 3 to ensure timely and continuous treatment after the operation.

[0035] Refer to Figures 4 to 6 , a drug loading groove 4 is opened on the inner side of the arc-shaped medicine storage tube 3. The drug loading groove 4 is usually a slender channel-like structure, and the inside satisfies the fluidity of drug injection to prevent drug leakage. Sixteen oval tubes 5 are fixedly connected to the outside of the wire frame 2. The oval tubes 5 are made of medical-grade rigid plastic, and their shapes are designed as ovals. Compared with circular tubes, the oval tubes 5 can better fit the internal structure of the sphenoid sinus cavity in a specific space and have more advantages in mechanical properties. An inlet 6 is opened on one side of the oval tube 5 close to the elastic sleeve 1, and the caliber of the inlet 6 can enable the drug flowing out of the arc-shaped medicine storage tube 3 to enter the oval tube 5 at a suitable flow rate. First elastic sheets 7 are fixedly connected to both the left and right sides inside the oval tube 5. The first elastic sheets 7 are made of thin and elastic metal sheets, such as medical-grade stainless steel sheets. Their function is to play a preliminary limiting role on the liquid outlet ball 9, so that the liquid outlet ball 9 can move within a specific position range.

[0036] The outside of the liquid outlet ball 9 is movably connected to the outside of the first elastic sheet 7. The liquid outlet ball 9 is usually made of a material with a smooth surface and certain hydrophilicity. A second elastic sheet 8 is also fixedly connected to one side of the oval tube 5 close to the elastic sleeve 1. The second elastic sheet 8 is similar to the first elastic sheet 7, but has different parameters such as elastic coefficient according to actual needs. The outside of the liquid outlet ball 9 is movably connected to the front end of the second elastic sheet 8, and a plurality of ball grooves 10 are opened on the outside of the liquid outlet ball 9. The ball grooves 10 are regularly distributed. When the drug flows through the liquid outlet ball 9, the ball grooves 10 can prompt the drug to form finer droplets, which helps the uniform dispersion of the drug.

[0037] Refer to Figure 7 、 Figure 8, a support assembly for fixing the elastic sleeve 1 is fixedly connected to the inner top end of the elastic sleeve 1. The support assembly includes a plurality of positioning blocks 11. The positioning blocks 11 are made of a material with high hardness and good biocompatibility, such as medical-grade titanium alloy. The outside of the positioning blocks 11 is fixedly connected to the inner wall top end of the elastic sleeve 1. There are eight positioning blocks 11, and the positioning blocks 11 are evenly distributed in position to ensure the stability of the subsequent support structure. A first connecting rod 12 is rotatably connected to the outside of the positioning blocks 11. There are eight first connecting rods 12. Generally, the first connecting rods 12 are made of light and high-strength materials, such as carbon fiber composite materials.

[0038] A first connecting block 13 is rotatably connected to the inner top end of the first connecting rod 12. The first connecting block 13 is made of an engineering plastic that is wear-resistant and has a certain toughness. A first moving groove 14 is formed on the outside of the first connecting block 13. The shape and size of the first moving groove 14 match the top end of the first connecting rod 12. The top end of the first connecting rod 12 is rotatably connected to the inner wall of the first moving groove 14. This connection method enables the first connecting rod 12 to rotate flexibly around the first moving groove 14. A first magnetic block 15 is fixedly connected to the bottom end of the first connecting block 13. A elastic tube 16 is fixedly connected to the bottom end of the first magnetic block 15. The elastic tube 16 is made of a material with good elasticity, such as a rubber tube with metal wires embedded inside to enhance toughness. It plays a role in storing and releasing elastic potential energy in the support assembly.

[0039] A second connecting rod 17 is rotatably connected to the middle of the first connecting rod 12. The second connecting rod 17 is similar to the first connecting rod 12, and light and high-strength materials are also selected for its material. A second connecting block 18 is rotatably connected to the adjacent end of the second connecting rod 17. The design of the second connecting block 18 has similarities with that of the first connecting block 13, but specific dimensions and connection methods are adjusted according to its function. A plurality of second moving grooves 19 are formed on the outside of the second connecting block 18. The shape and position design of the second moving grooves 19 are designed to cooperate with the movement of the second connecting rod 17. The top end of the second connecting rod 17 is rotatably connected to the inner wall of the second moving grooves 19. A second magnetic block 20 is fixedly connected to the top end of the second connecting block 18. The second magnetic block 20 cooperates with the first magnetic block 15 at the bottom end of the first connecting block 13. When the second magnetic block 20 is adsorbed and fixed to the first magnetic block 15, the unfolded state of the support assembly can be effectively locked. The top end of the first magnetic block 15 is detachably connected to the top end of the second magnetic block 20. A clamping groove 21 is formed in the middle of the second magnetic block 20. The top end of the elastic tube 16 is fixedly connected to the inner wall of the clamping groove 21. Through the connection of the clamping groove 21, the connection relationship between the elastic tube 16 and the second magnetic block 20 and the entire support assembly is further stabilized.

[0040] Working principle: When using this stent, the stent is brought into the sphenoid sinus area in the patient's nasal sinus through the balloon delivery rod. Then, the balloon in the middle of the elastic sleeve 1 is inflated along the pipeline by the external air pressure, so that the head of the balloon squeezes the top of the second connecting block 18, causing the second connecting block 18 to move upward along the elastic tube 16, driving the elastic tube 16 to compress. After that, the second magnet 20 adsorbs and fixes to the first magnet 15 of the first connecting block 13. While the second connecting block 18 rotates, the second connecting rod 17 outside the second connecting block 18 will support the first connecting rod 12 to expand around the first movable groove 14 under the movement of the second connecting block 18, so that the elastic sleeve 1 is fixed into a cylindrical shape and supported in the sphenoid sinus cavity, effectively preventing the movement of the sphenoid sinus stent.

[0041] Different drugs are stored in the arc-shaped medicine storage tube 3 of the sphenoid sinus stent, and a plurality of liquid outlet balls 9 are provided at the cross joints of the stent. When the patient breathes, the polyps in the sphenoid sinus cavity are driven to squeeze the outside of the wire mesh 2 during breathing. At this time, the polyps will drive the liquid outlet balls 9 to rotate inside the elliptical tube 5, so that the different drugs stored in the arc-shaped medicine storage tube 3 will flow out along the outside of the liquid outlet balls 9, which helps to distribute the drugs more evenly, improve the bioavailability of multiple drugs, and solve various postoperative symptoms of the patient.

[0042] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A conformal sphenoid sinus stent for postoperative transnasal endoscopy with sustained-release drug delivery, comprising an elastic sleeve (1) and a liquid outlet sphere (9), characterized in that: The outer part of the elastic sleeve (1) is fixedly connected with a grid frame (2). The top end of the grid frame (2) is provided with an arc-shaped medicine storage tube (3). The outer part of the grid frame (2) is fixedly connected with a plurality of elliptical tubes (5). A liquid inlet (6) is formed on one side of the elliptical tube (5) close to the elastic sleeve (1). On both the left and right sides inside the elliptical tube (5), a first elastic sheet (7) is fixedly connected. On one side of the elliptical tube (5) close to the elastic sleeve (1), a second elastic sheet (8) is fixedly connected. At the top end inside the elastic sleeve (1), a support assembly for fixing the elastic sleeve (1) is fixedly connected.

2. The conformable sphenoid sinus stent for sustained-release drug delivery according to claim 1, characterized in that: The support assembly includes a plurality of positioning blocks (11). The outer part of the positioning block (11) is fixedly connected to the inner wall top end of the elastic sleeve (1). The outer part of the positioning block (11) is rotatably connected with a first connecting rod (12). The inner top end of the first connecting rod (12) is rotatably connected with a first connecting block (13). The bottom end of the first connecting block (13) is fixedly connected with a first magnet (15). The bottom end of the first magnet (15) is fixedly connected with an elastic tube (16).

3. The conformable sphenoid sinus stent for postoperative slow-release drug delivery according to claim 2, wherein: The middle part of the first connecting rod (12) is rotatably connected with a second connecting rod (17). The adjacent ends of the second connecting rod (17) are rotatably connected with a second connecting block (18). The top end of the second connecting block (18) is fixedly connected with a second magnet (20). A card slot (21) is formed in the middle of the second magnet (20).

4. The conformable sphenoid sinus stent for sustained-release drug delivery according to claim 1, wherein: A medicine loading groove (4) is formed on the inner side of the arc-shaped medicine storage tube (3). The outer part of the liquid outlet ball (9) is movably connected to the outer part of the first elastic sheet (7).

5. The conformable sphenoid sinus stent for sustained-release drug administration according to claim 3, wherein: The top end of the elastic tube (16) is fixedly connected to the inner wall of the card slot (21). The top end of the first magnet (15) is detachably connected to the top end of the second magnet (20).

6. The conformable sphenoid sinus stent for sustained-release drug delivery according to claim 1, wherein: The outer part of the liquid outlet ball (9) is movably connected to the front end of the second elastic sheet (8). A plurality of ball grooves (10) are formed on the outer part of the liquid outlet ball (9).

7. The conformal sphenoid sinus stent for postoperative transnasal endoscopy with sustained-release drug delivery according to claim 2, wherein: A first movable groove (14) is formed on the outer part of the first connecting block (13). The top end of the first connecting rod (12) is rotatably connected to the inner wall of the first movable groove (14).

8. The conformable sphenoid sinus stent for sustained-release drug administration according to claim 3, wherein: A plurality of second movable grooves (19) are formed on the outer part of the second connecting block (18). The top end of the second connecting rod (17) is rotatably connected to the inner wall of the second movable groove (19).

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