Wet tissue liquid medicine and wet tissue preparation method

Abstract

The invention relates to the technical field of wet tissue production, in particular to wet tissue liquid medicine which comprises preservative mother liquor and wet tissue base liquid, the preservative mother liquor comprises any one or more plant extracts of rhizome and leaf extracts, flower extracts and fruit and seed extracts with preservative effects, and the preservative mother liquor comprises one or more plant extracts of the root and leaf extracts, the flower extracts and the fruit and seed extracts. The wet tissue base solution comprises water, a natural chelating agent, a natural buffering agent and a natural surfactant, a wet tissue prepared from the wet tissue liquid medicine is suitable for infants, stimulation or health hazards to human bodies are not likely to be generated, and the raw materials are all natural components, easy to degrade and not likely to damage the environment.

Description

Technical Field

[0001] The present application relates to the field of wet wipe production technology, and in particular, to a wet wipe liquid medicine and a method for preparing wet wipes. Background Art

[0002] Wet wipes are a multi-purpose cleaning product. In order to prevent the moisture-rich wet wipes from deteriorating, preservatives must be added to the wet wipe liquid medicine. Currently, the preservatives with a high usage frequency in wet wipes are chemical preservatives, such as methylisothiazolinone, methylchloroisothiazolinone, phenoxyethanol, etc. When some sensitive skin or the skin of infants touches a part of the chemical preservatives, allergies are likely to occur.

[0003] In addition, after the wet wipes are used and discarded, the chemical preservatives in them are difficult to decompose naturally. Once they enter natural water bodies, they are likely to cause pollution. For example, triclocarban has ecological toxicity to algae and fish.

[0004] There are also some formaldehyde-releasing preservatives in wet wipes, such as DMDM hydantoin and quaternium-15, which will slowly release formaldehyde and increase the carcinogenic risk during long-term human contact.

[0005] Therefore, at home and abroad, the control of chemical preservatives, especially in terms of infant use, human health and environmental protection, has become increasingly strict. Therefore, it is required that wet wipes are green, safe and not easily irritating to the human body while meeting certain anti-corrosion effects. Summary of the Invention

[0006] In order to make the wet wipes have the characteristics of being green and safe, the present application provides a wet wipe liquid medicine and a method for preparing wet wipes.

[0007] In a first aspect, a wet wipe liquid medicine provided by the present application adopts the following technical solution.

[0008] A wet wipe liquid medicine includes a preservative mother liquor and a wet wipe base liquid. The preservative mother liquor includes any one or several of rhizome, leaf and stem extracts, flower extracts, fruit and seed extracts with preservative effects, and natural synergists. The wet wipe base liquid includes water, natural chelating agents, natural buffering agents and natural surfactants.

[0009] By adopting the above technical solution, the wet wipe liquid medicine selects plant extracts or natural synergists and is combined with a wet wipe base liquid of natural components, so that the wet wipes are not easily irritating to infants, and are not easily damaging to the environment when discarded after use.

[0010] Optionally, the rhizome, leaf and stem extracts include any one or several of oat bran extract, sophora flavescens root extract, moutan root bark extract, hinoki leaf extract, lophatherum gracile extract, ginkgo leaf extract, tea extract, olive leaf extract and cinnamon extract.

[0011] Optionally, the flower extract includes any one or several of Artemisia capillaris flower extract, clove flower extract, honeysuckle flower extract, dandelion extract, and hop flower extract.

[0012] Optionally, the fruit extract includes any one or several of lemon fruit extract, grapefruit seed extract, soybean seed extract, pomegranate seed extract, chili fruit extract, and garlic extract.

[0013] Optionally, the natural synergist includes any one or several of natural caprylyl glycol, natural ethylhexylglycerin, natural raspberry ketone, natural octanoyl hydroxamic acid, natural hexylene glycol, natural pentylene glycol, natural gluconolactone, and natural butanediol.

[0014] By adopting the above technical solution, a suitable antiseptic mother liquor can be configured according to needs.

[0015] Optionally, the wet wipe liquid medicine of the present application includes the following components by weight percentage: oat bran extract: 0.3% - 1%, sophora flavescens root extract: 0.1% - 0.5%, soybean seed extract: 0.03% - 0.1%, natural chelating agent: 0.8% - 1.2%, natural surfactant: 0.5% - 1.5%, natural buffer: 0.5% - 1.5%, and the balance is water.

[0016] Optionally, the wet wipe liquid medicine of the present application includes the following components by weight percentage: oat bran extract: 0.5%, sophora flavescens root extract: 0.2%, soybean seed extract: 0.05%, natural chelating agent: 1.0%, natural surfactant: 1.0%, natural buffer: 1.0%, and the balance is water.

[0017] By adopting the above technical solution, a wet wipe liquid medicine is configured with plant extracts represented by rhizome, leaf and stem extracts, and the corresponding optimal ratio is obtained, so that the antiseptic property, skin irritation, degradability and other aspects of the wet wipe liquid medicine are relatively balanced.

[0018] Optionally, the wet wipe liquid medicine of the present application includes the following components by weight percentage: natural caprylyl glycol: 0.03% - 0.1%, natural ethylhexylglycerin: 0.03% - 0.1%, natural raspberry ketone: 0.005% - 0.03%, natural octanoyl hydroxamic acid: 0.005 - 0.03%, natural butanediol: 0.1% - 0.5%, natural chelating agent: 0.005% - 0.03%, natural surfactant: 0.005% - 0.03%, natural buffer: 0.0005% - 0.03%, and the balance is water.

[0019] Optionally, the wet wipe liquid medicine of the present application comprises the following components by weight percentage: natural caprylyl glycol: 0.05%, natural ethylhexyl glycerin: 0.05%, natural raspberry ketone: 0.01%, natural octanoyl hydroxamic acid: 0.01%, natural butanediol: 0.2%, natural chelating agent: 0.01%, natural surfactant: 0.01%, natural buffer: 0.002%, and the balance is water.

[0020] By adopting the above technical solution, a natural synergist is used to prepare the wet wipe liquid medicine, and the corresponding optimal ratio is obtained, so that the wet wipe liquid medicine is relatively balanced in terms of anti-corrosion property, skin irritation and degradability.

[0021] In a second aspect, a wet wipe preparation method provided by the present application adopts the following technical solution.

[0022] A wet wipe preparation method uses the above-mentioned wet wipe liquid medicine, and specifically comprises the following steps.

[0023] Step 1: Stir and mix any one or several of the rhizome, leaf and stem extract, flower extract, fruit and seed extract, and natural synergist to form an anti-corrosion mother liquor;

[0024] Step 2: Stir and mix the anti-corrosion mother liquor with the wet wipe base liquid to form a wet wipe liquid medicine;

[0025] Step 3: The wet wipe carrier is first folded and then impregnated with the wet wipe liquid medicine, and then cut, stacked and packaged.

[0026] By adopting the above technical solution, wet wipes with low irritation to infants and young children and easy decomposition are manufactured.

[0027] In summary, the present application includes at least the following beneficial effects:

[0028] 1. The wet wipe liquid medicine is natural in source, more environmentally friendly and safer;

[0029] 2. The wet wipe liquid medicine consists of two parts, an anti-corrosion mother liquor and a wet wipe base liquid, and the preparation is more convenient;

[0030] 3. The wet wipe liquid medicine system is stable and has good anti-corrosion effect. Detailed implementation mode

[0031] The present application discloses a wet wipe liquid medicine, which comprises an anti-corrosion mother liquor and a wet wipe base liquid. The anti-corrosion mother liquor comprises any one or several of the rhizome, leaf and stem extract, flower extract, fruit and seed extract and natural synergist with anti-corrosion effect, and the wet wipe base liquid comprises water, natural chelating agent, natural buffer and natural surfactant.

[0032] The rhizome, leaf and stem extracts include any one or several of oat bran extract, sophora flavescens root extract, moutan root bark extract, hinoki leaf extract, lophatherum gracile extract, ginkgo biloba leaf extract, tea extract, olive leaf extract and cinnamon extract. The flower extracts include any one or several of artemisia capillaris flower extract, clove flower extract, honeysuckle flower extract, dandelion extract and hops flower extract. The fruit extracts include any one or several of lemon fruit extract, grapefruit seed extract, soybean seed extract, pomegranate seed extract, chili fruit extract and garlic extract. The natural synergists include any one or several of natural caprylyl glycol, natural ethylhexylglycerin, natural raspberry ketone, natural octanoyl hydroxamic acid, natural hexylene glycol, natural pentylene glycol, natural gluconolactone and natural butanediol.

[0033] In addition, in this embodiment, the natural chelating agent can be selected as natural sodium phytate, which is used to chelate metal ions in water, inhibit oxidation and precipitation, and help to stabilize the active ingredients in the preservative mother liquor. The natural buffer can be selected as a mixed solution of natural citric acid and natural sodium citrate with the same weight ratio. Natural citric acid adjusts the pH of the wet wipe liquid medicine to weakly acidic so that the pH of the wet wipe is closer to the pH of the baby's skin. Natural sodium citrate is used to buffer the pH fluctuation of the wet wipe liquid medicine and enhance the stability of the wet wipe liquid medicine system. The natural surfactant can be selected as alkyl polyglycoside, which gently cleans, has high skin compatibility, does not damage the skin barrier function, and is suitable for babies and sensitive skin.

[0034] In this embodiment, since the rhizome, leaf and stem extracts, flower extracts and fruit and seed extracts are all extracts of the active ingredients in plants that can play an anti-corrosion role, and their performances are relatively close in all aspects, several of the rhizome, leaf and stem extracts and natural synergists are selected as representatives below to further illustrate the specific ratio of the wet wipe liquid medicine.

[0035] The proportion of the wet wipe liquid medicine prepared with the rhizome, leaf and stem extracts as the preservative mother liquor is as follows:

[0036] By weight percentage, it includes the following components: oat bran extract: 0.3% - 1%, sophora flavescens root extract: 0.1% - 0.5%, soybean seed extract: 0.03% - 0.1%, natural chelating agent: 0.8% - 1.2%, natural surfactant: 0.5% - 1.5%, natural buffer: 0.5% - 1.5%, and the rest is water.

[0037] The proportion of the wet wipe liquid medicine prepared with the natural synergist as the preservative mother liquor is as follows:

[0038] Comprising the following components by weight percentage: natural caprylyl glycol: 0.03% - 0.1%, natural ethylhexylglycerin: 0.03% - 0.1%, natural raspberry ketone: 0.005% - 0.03%, natural octanoyl hydroxamic acid: 0.005 - 0.03%, natural butanediol: 0.1% - 0.5%, natural chelating agent: 0.005% - 0.03%, natural surfactant: 0.005% - 0.03%, natural buffer: 0.0005% - 0.03%, the balance being water.

[0039] The following designs several examples and comparative examples to verify the above two wet wipe liquid medicines.

[0040] Example 1:

[0041] Comprising the following components by weight percentage: oat bran extract: 0.3%, sophora flavescens root extract: 0.1%, soybean seed extract: 0.03%, natural chelating agent: 0.8%, natural surfactant: 0.5%, natural buffer: 0.5%, the balance being water.

[0042] Example 2:

[0043] Comprising the following components by weight percentage: oat bran extract: 1%, sophora flavescens root extract: 0.5%, soybean seed extract: 0.1%, natural chelating agent: 1.2%, natural surfactant: 1.5%, natural buffer: 1.5%, the balance being water.

[0044] Example 3:

[0045] Comprising the following components by weight percentage: oat bran extract: 0.5%, sophora flavescens root extract: 0.2%, soybean seed extract: 0.05%, natural chelating agent: 1%, natural surfactant: 1%, natural buffer: 1%, the balance being water.

[0046] Comparative Example 1:

[0047] Comprising the following components by weight percentage: oat bran extract: 0.2%, sophora flavescens root extract: 0.05%, soybean seed extract: 0.01, natural chelating agent: 0.4%, natural surfactant: 0.2%, natural buffer: 0.2%, the balance being water.

[0048] Comparative Example 2:

[0049] Comprising the following components by weight percentage: oat bran extract: 1.2%, sophora flavescens root extract: 0.6%, soybean seed extract: 0.15%, natural chelating agent: 1.4%, natural surfactant: 1.7%, natural buffer: 1.7%, the balance being water.

[0050] Example 4:

[0051] It comprises the following components by weight percentage: natural caprylyl glycol: 0.03%, natural ethylhexylglycerin: 0.03%, natural raspberry ketone: 0.005%, natural octanoyl hydroxamic acid: 0.005, natural butanediol: 0.1%, natural chelating agent: 0.005%, natural surfactant: 0.005%, natural buffer: 0.0005%, and the balance is water.

[0052] Example Five:

[0053] It comprises the following components by weight percentage: natural caprylyl glycol: 0.1%, natural ethylhexylglycerin: 0.1%, natural raspberry ketone: 0.03%, natural octanoyl hydroxamic acid: 0.03%, natural butanediol: 0.5%, natural chelating agent: 0.03%, natural surfactant: 0.03%, natural buffer: 0.03%, and the balance is water.

[0054] Example Six:

[0055] It comprises the following components by weight percentage: natural caprylyl glycol: 0.05%, natural ethylhexylglycerin: 0.05%, natural raspberry ketone: 0.01%, natural octanoyl hydroxamic acid: 0.01%, natural butanediol: 0.2%, natural chelating agent: 0.01%, natural surfactant: 0.01%, natural buffer: 0.002%, and the balance is water.

[0056] Comparative Example Three:

[0057] It comprises the following components by weight percentage: natural caprylyl glycol: 0.02%, natural ethylhexylglycerin: 0.02%, natural raspberry ketone: 0.003%, natural octanoyl hydroxamic acid: 0.003%, natural butanediol: 0.08%, natural chelating agent: 0.003%, natural surfactant: 0.003%, natural buffer: 0.0002%, and the balance is water.

[0058] Comparative Example Four:

[0059] It comprises the following components by weight percentage: natural caprylyl glycol: 0.12%, natural ethylhexylglycerin: 0.12%, natural raspberry ketone: 0.05%, natural octanoyl hydroxamic acid: 0.05%, natural butanediol: 0.6%, natural chelating agent: 0.05%, natural surfactant: 0.05%, natural buffer: 0.04%, and the balance is water.

[0060] After obtaining the above ten kinds of wet wipe liquid medicines, the following relevant indexes are tested.

[0061] Antiseptic property: Referring to the antiseptic efficacy test in Standard ISO 11930, the inoculated bacteria are Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Aspergillus brasiliensis, and Candida albicans. For wet wipe liquid medicine suitable for infants, it is required that the logarithmic reduction of bacteria is ≥3 log within 3 days, and the total number of microorganisms is ≤10 CFU / g within 28 days.

[0062] Stability: Referring to Standard ICH Q1A for a three-month accelerated aging test, and referring to Standard GB 15979 to detect the initial pH, pH after 3 months, retention rate of antiseptic active ingredients, and total number of microbial growth of the wet wipe liquid medicine. For wet wipe liquid medicine meeting the infant standard, the required pH is 5.5 - 6.5, and the retention rate of active ingredients is ≥85%.

[0063] Skin irritation: Referring to Standard OECD 439 for the test, for wet wipe liquid medicine suitable for infants, it is required that the cell survival rate is ≥80% after 24-hour contact.

[0064] Degradability: Referring to Standard OECD 301D for the test, a biodegradation rate of ≥60% within 28 days is considered up to standard.

[0065] The relevant test results are shown in the following two tables.

[0066] Table 1:

[0067]

[0068] It can be seen from Table 1 that Example 1 and Example 4 are not suitable for infant use and can be used for general adult use. Example 2, Example 3, Example 5, and Example 6 meet the infant use standards in terms of antiseptic property and stability. In Comparative Example 1 and Comparative Example 3, the proportion of the antiseptic mother liquor is too low to achieve the antiseptic effect. In Comparative Example 2, natural sodium phytate is prone to crystal precipitation, resulting in the wet wipe solution being too acidic, causing the sophora flavescens root extract to decompose due to excessive acidity and resulting in rancidity. The same rancidity occurs in Comparative Example 4, leading to a decrease in the retention rate of active ingredients.

[0069] Table 2:

[0070]

[0071] It can be seen from Table 2 that Example 2 and Example 5 are initially near the critical value of the infant standard in terms of skin irritation and are not very suitable for infants and people with sensitive skin. There is a relatively large gap between Comparative Example 2 and Comparative Example 4 and the infant use standard. And in terms of degradability, only Comparative Example 2 and Comparative Example 4 do not meet the standard.

[0072] Based on the data in Table 1 and Table 2, it can be known that Example 3 and Example 6 can meet the relevant standards in all four aspects of antiseptic property, stability, skin irritation, and degradability, and also meet the higher standards for infant and sensitive skin population use.

[0073] The implementation principle of a wet wipe liquid medicine in this application is as follows: using natural preservative components as the preservative mother liquor, such as extracts of rhizomes, leaves, flowers, fruits and seeds, and natural synergists, etc., and combining with the wet wipe base liquid of natural components, so that the finally mixed wet wipe liquid medicine is green and safe, can be better applied to infants or people with sensitive skin, and can be positioned in the mid - to - high - end market.

[0074] This application also discloses a method for preparing wet wipes, which specifically includes the following steps.

[0075] Step 1: Stir and mix any one or several of the extracts of rhizomes, leaves, flowers, fruits and seeds, and natural synergists to form a preservative mother liquor.

[0076] Step 2: Stir and mix the preservative mother liquor with the wet wipe base liquid to form a wet wipe liquid medicine.

[0077] Step 3: The wet wipe carrier is first folded and then impregnated with the wet wipe liquid medicine, and then cut, stacked and packaged.

[0078] Among them, the wet wipe carrier can be non - woven fabric or woven fabric. The non - woven fabric is selected from cellulose fiber, viscose / polyester composite fabric, all - polyester fabric, viscose / wood pulp composite fabric, tencel / wood pulp composite fabric, and other non - woven fabrics with similar structures and compositions. In this embodiment, the wet wipe carrier is cellulose fiber, which improves the overall degradability of the wet wipe.

[0079] The implementation principle of a method for preparing wet wipes in an embodiment of this application is as follows: the wet wipe liquid medicine is convenient to configure, and the whole wet wipe is easily degradable.

[0080] The above are all preferred embodiments of this application. The protection scope of this application is not limited by this. Therefore, all equivalent changes made according to the structure, shape and principle of this application should be covered within the protection scope of this application.

Claims

1. A wet wipe liquid medicine, characterized in that: It includes an anti-corrosion mother liquor and a wet wipe base liquor. The anti-corrosion mother liquor includes any one or several of rhizome, leaf and stem extracts, flower extracts, fruit and seed extracts with anti-corrosion effects, and natural synergists. The wet wipe base liquor includes water, natural chelating agents, natural buffering agents and natural surfactants.

2. The wet wipe liquid medicine according to claim 1, characterized in that: The rhizome, leaf and stem extracts include any one or several of oat bran extracts, sophora flavescens root extracts, moutan root bark extracts, hinoki leaf extracts, lophatherum gracile extracts, ginkgo leaf extracts, tea extracts, olive leaf extracts and cinnamon extracts.

3. A wet wipe liquid medicine according to claim 1, characterized in that: The flower extracts include any one or several of artemisia capillaris flower extracts, lilac flower extracts, honeysuckle flower extracts, dandelion extracts and hops flower extracts.

4. A wet wipe liquid medicine according to claim 1, characterized in that: The fruit extracts include any one or several of lemon fruit extracts, grapefruit seed extracts, soybean seed extracts, pomegranate seed extracts, chili fruit extracts and garlic extracts.

5. A wet wipe liquid medicine according to claim 1, characterized in that: The natural synergists include any one or several of natural caprylyl glycol, natural ethylhexylglycerin, natural raspberry ketone, natural octanoyl hydroxamic acid, natural hexylene glycol, natural pentylene glycol, natural gluconolactone and natural butanediol.

6. The wet wipe liquid medicine according to claim 1 or 2, characterized in that: By weight percentage, it includes the following components: oat bran extract: 0.3% - 1%, sophora flavescens root extract: 0.1% - 0.5%, soybean seed extract: 0.03% - 0.1%, natural chelating agent: 0.8% - 1.2%, natural surfactant: 0.5% - 1.5%, natural buffering agent: 0.5% - 1.5%, and the balance is water.

7. A wet wipe liquid medicine according to claim 6, characterized in that: By weight percentage, it includes the following components: oat bran extract: 0.5%, sophora flavescens root extract: 0.2%, soybean seed extract: 0.05%, natural chelating agent: 1.0%, natural surfactant: 1.0%, natural buffering agent: 1.0%, and the balance is water.

8. A wet wipe liquid medicine according to claim 1 or 5, characterized in that: By weight percentage, it includes the following components: natural caprylyl glycol: 0.03% - 0.1%, natural ethylhexylglycerin: 0.03% - 0.1%, natural raspberry ketone: 0.005% - 0.03%, natural octanoyl hydroxamic acid: 0.005 - 0.03%, natural butanediol: 0.1% - 0.5%, natural chelating agent: 0.005% - 0.03%, natural surfactant: 0.005% - 0.03%, natural buffering agent: 0.0005% - 0.03%, and the balance is water.

9. A wet wipe liquid medicine according to claim 8, characterized in that: By weight percentage, it includes the following components: natural caprylyl glycol: 0.05%, natural ethylhexylglycerin: 0.05%, natural raspberry ketone: 0.01%, natural octanoyl hydroxamic acid: 0.01%, natural butanediol: 0.2%, natural chelating agent: 0.01%, natural surfactant: 0.01%, natural buffering agent: 0.002%, and the balance is water.

10. A method for preparing wet wipes, using a wet wipe liquid medicine described in any one of claims 1-9, characterized in that: Specifically, it includes the following steps: Step 1: Stir and mix any one or several of the rhizome, leaf and stem extracts, flower extracts, fruit and seed extracts, and natural synergists to form an anti-corrosion mother liquor; Step 2: Stir and mix the anti-corrosion mother liquor with the wet wipe base liquor to form a wet wipe medicinal liquid; Step 3: The wet wipe carrier is first folded and then impregnated with the wet wipe medicinal liquid, and then cut, stacked and packaged.

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