Micro-fluidic chip and micro-fluidic device

Abstract

The invention discloses a micro-fluidic chip and a micro-fluidic device, and the micro-fluidic chip comprises a driving array which comprises a plurality of driving units arranged in an array; the data signal lines extend in the column direction, and the data signal lines are electrically connected with one column of driving units; the detection signal input units are electrically connected with the data signal lines; the driving array detection units are electrically connected with the data signal lines; the detection signal input unit is configured to transmit a detection signal to the driving unit in a first detection stage; and the driving array detection unit is configured to start working and collect the driving current output by each driving unit in the driving unit column according to the detection signal in the second detection stage after the first detection stage is completed. The driving performance of each driving unit is accurately detected by arranging the detection signal input unit and the driving array detection unit, so that the performance of the micro-fluidic chip is ensured.

Description

Technical Field

[0001] The present invention relates to the field of microfluidic technology, and particularly to a microfluidic chip and a microfluidic device. Background Art

[0002] Microfluidic chips have powerful integration, and when processing samples, they have fast analysis speed, low loss, less material consumption, and little pollution. Therefore, microfluidic chips have extremely broad application prospects in many fields such as biomedical research, drug synthesis screening, environmental monitoring and protection, health quarantine, forensic identification, and detection of biological reagents.

[0003] Existing microfluidic chips are mainly used to drive the flow of droplets. During the actual driving process of microfluidic chips, the driving voltage required for the operation of the microfluidic driving electrode array is relatively high, which poses a challenge to the microfluidic driving electrode array. Summary of the Invention

[0004] The present invention provides a microfluidic chip and a microfluidic device to achieve precise detection of driving units in a driving array and ensure the performance of the microfluidic chip.

[0005] In a first aspect, the present invention provides a microfluidic chip, including:

[0006] A driving array, which includes a plurality of driving units arranged in an array;

[0007] A plurality of data signal lines, which extend along the column direction and are electrically connected to a column of driving units;

[0008] A plurality of detection signal input units, which are electrically connected to the data signal lines;

[0009] A plurality of driving array detection units, which are electrically connected to the data signal lines;

[0010] The detection signal input unit is configured to transmit a detection signal to the driving unit during a first detection stage;

[0011] The driving array detection unit is configured to start working and collect the driving current output by each driving unit in the driving unit column according to the detection signal during a second detection stage after the first detection stage is completed.

[0012] In a second aspect, the present invention provides a microfluidic device, which includes the microfluidic chip according to any one of the first aspect.

[0013] In the technical solution of the embodiment of the present invention, a microfluidic chip is provided by the present invention, including: a driving array, the driving array includes a plurality of driving units arranged in an array; a plurality of data signal lines, the data signal lines extend along the column direction, and the data signal lines are electrically connected to a column of driving units; a plurality of detection signal input units, the detection signal input units are electrically connected to the data signal lines; a plurality of driving array detection units, the driving array detection units are electrically connected to the data signal lines; the detection signal input units are configured to transmit detection signals to the driving units in the first detection stage; the driving array detection units are configured to start working and collect the driving currents output by each driving unit in the driving unit column according to the detection signals after the first detection stage is completed. The detection signal input units are used to transmit detection signals to each driving unit, and then the driving array detection units are used to collect the driving currents output by each driving unit, and the driving currents are analyzed to determine the driving performance of each driving unit, thereby ensuring the performance of the microfluidic chip.

[0014] It should be understood that the content described in this part is not intended to identify the key or important features of the embodiments of the present invention, nor is it used to limit the scope of the present invention. Other features of the present invention will become easily understood through the following description. Brief Description of the Drawings

[0015] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0016] Figure 1 It is a schematic structural diagram of a microfluidic chip provided by an embodiment of the present invention;

[0017] Figure 2 It is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention;

[0018] Figure 3 It is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention;

[0019] Figure 4 It is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention;

[0020] Figure 5 It is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention;

[0021] Figure 6 It is a schematic diagram of a detection signal provided by an embodiment of the present invention;

[0022] Figure 7 Another schematic diagram of the detection signal provided by the embodiment of the present invention;

[0023] Figure 8 Another schematic diagram of the detection signal provided by the embodiment of the present invention;

[0024] Figure 9 Another schematic diagram of the detection signal provided by the embodiment of the present invention;

[0025] Figure 10 Another schematic structural diagram of the microfluidic chip provided by the embodiment of the present invention;

[0026] Figure 11 Another schematic structural diagram of the microfluidic chip provided by the embodiment of the present invention;

[0027] Figure 12 Another schematic structural diagram of the microfluidic chip provided by the embodiment of the present invention;

[0028] Figure 13 Another schematic structural diagram of the microfluidic chip provided by the embodiment of the present invention;

[0029] Figure 14 Another schematic structural diagram of the microfluidic chip provided by the embodiment of the present invention;

[0030] Figure 15 Another schematic structural diagram of the microfluidic chip provided by the embodiment of the present invention. Detailed implementation manners

[0031] In order to enable those skilled in the art to better understand the solution of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0032] It should be noted that the terms "first", "second", etc. in the description, claims and above-mentioned drawings of the present invention are used to distinguish similar objects and do not necessarily need to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged under appropriate circumstances so that the embodiments of the present invention described here can be implemented in an order other than those illustrated or described here. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units does not necessarily have to be limited to those steps or units clearly listed, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0033] Figure 1 The following is a schematic structural diagram of a microfluidic chip provided by an embodiment of the present invention. As Figure 1 shown, the microfluidic chip 101 includes a driving array 102, and the driving array 102 includes a plurality of driving units 103 arranged in an array; a plurality of data signal lines 104, the data signal lines 104 extend along the column direction Y, and the data signal lines 104 are electrically connected to a column of driving units 103; a plurality of detection signal input units 105, the detection signal input units 105 are electrically connected to the data signal lines 104; a plurality of driving array detection units 106, the driving array detection units 106 are electrically connected to the data signal lines 104; the detection signal input unit 105 is configured to transmit a detection signal to the driving unit 103 in the first detection stage; the driving array detection unit 106 is configured to start working and collect the driving current I output by each driving unit 103 in the driving unit column 1021 according to the detection signal after the first detection stage is completed ref .

[0034] Among them, the microfluidic chip 101 includes a substrate and a driving array 102 located on the substrate. The driving array 102 includes a plurality of driving units 103 arranged in an array, and is exemplarily shown as a 3×3 driving array. The driving unit 103 may include a driving electrode. By applying a corresponding driving voltage to the driving electrode, a driving electric field is formed, and then the droplets located in the radiation area of the driving electric field are controlled to move in a certain direction. However, during the actual droplet driving process of the microfluidic chip 101, there may be a problem that the voltage of the driving electrode is insufficient or fails, resulting in the droplets stopping at certain positions, but it is difficult for users to observe intuitively. In the embodiment of the present invention, a plurality of data signal lines 104 extending along the column direction Y and a plurality of scan signal lines 107 extending along the row direction X are provided in the microfluidic chip 101. The same data signal line 104 is electrically connected to a column of driving units 103, and the same scan signal line 107 is electrically connected to a row of driving units 103. When the microfluidic chip 101 is in the working stage, when a data signal line 104 transmits a data signal to a column of driving units 103, each scan signal line 107 transmits a scan signal to each row of driving units 103 in a time-division manner, so as to ensure that each driving unit 103 is correspondingly activated, and then drive the droplets in the microfluidic chip 101 to move. A plurality of detection signal input units 105 are also provided in the microfluidic chip 101. One detection signal input unit 105 is electrically connected to a data signal line 104. When the microfluidic chip 101 is in the detection stage, the detection stage includes a first detection stage and a second detection stage. The detection signal input unit 105 transmits a detection signal to the driving unit 103 through the data signal line 104 in the first detection stage, and cooperates with the time-division transmission of the scan signal by the scan signal line 107 to realize the time-division writing of the detection signal to the adjacent driving units 103 in the same column, so that the detection signals written by the driving units 103 in the same column can be different. The detection signals written by the driving units 103 corresponding to the odd rows in the same column are the same, and the detection signals written by the driving units 103 corresponding to the even rows in the same column are the same. Each driving unit 103 stores the written detection signal to ensure the accurate detection of each driving unit 103. A plurality of driving array detection units 106 are also provided in the microfluidic chip 101. In the second detection stage, the detection signal input unit 105 stops working, and the driving array detection unit 106 starts to work. One driving array detection unit 106 is electrically connected to a data signal line 104, and cooperates with the time-division transmission of the scan signal by the scan signal line 107. Each driving unit 103 in a column of driving units column 1021 will output a driving current I ref , and the driving array detection unit 106 collects the driving current I ref of each driving unit 103 in a column of driving units column 1021, and then judges the driving current I refWhether it corresponds to the detected signal written correspondingly. If it corresponds, it is considered that the driving unit 103 is normal and the driving electrode is effective at this time; if it does not correspond, it is considered that the driving unit 103 is abnormal and the driving electrode fails at this time. By setting a plurality of detection writing units and a plurality of driving array detection units 106 in the microfluidic chip 101, the detection of each driving unit 103 in the driving array 102 is realized, and the driving effect of the microfluidic chip 101 on the droplets is ensured.

[0035] In the embodiment of the present invention, by setting a plurality of detection signal input units and a plurality of driving array detection units in the microfluidic chip, the detection signal input unit is electrically connected to the data signal line, the driving array detection unit is electrically connected to the data signal line, the detection signal input unit transmits a detection signal to the driving unit in the first detection stage; the driving array detection unit starts to work and collects the driving current output by each driving unit in the driving unit column according to the detection signal in the second detection stage. The driving performance of each driving unit is determined by analyzing the driving current output by each driving unit according to the detection signal, thereby ensuring the performance of the microfluidic chip.

[0036] Optionally, Figure 2 is a schematic structural diagram of another microfluidic chip provided by the embodiment of the present invention. As Figure 1 and Figure 2 shown, the microfluidic chip 101 further includes a plurality of scan signal lines 107, the scan signal lines 107 extend along the row direction X, and the scan signal lines 107 are electrically connected to a row of driving units 103; the driving unit 103 includes a driving transistor 1031 and a capacitor 1032; the first pole of the driving transistor 1031 is electrically connected to the data signal line 104, the second pole of the driving transistor 1031 is electrically connected to the first electrode plate of the capacitor 1032, the gate of the driving transistor 1031 is electrically connected to the scan signal line 107, and the second electrode plate of the capacitor 1032 is connected to the common voltage signal VCOM.

[0037] Among them, the plurality of scan signal lines 107 are turned on in a time-sharing manner, and are combined with the signal transmitted by the data signal line 104 to realize the individual control of each driving unit 103 in the driving array 102. Writing the detection signal transmitted in the data signal line 104 into the corresponding driving unit 103 in the first detection stage and the driving current I transmitted in the data signal line 104 in the second detection stage refThe drive unit 103 includes a drive transistor 1031 and a capacitor 1032. The first electrode of the drive transistor 1031 is electrically connected to the data signal line 104. The gate of the drive transistor 1031 is connected to the scanning signal line 107. The second electrode of the drive transistor 1031 is electrically connected to the first plate of the capacitor 1032. The second substrate of the capacitor 1032 is electrically connected to the common voltage signal VCOM. In the first detection stage, the capacitor 1032 corresponding to the drive transistor 1031 can store the written detection signal, thereby ensuring that in the second detection stage, each drive unit 103 in a column can output the drive current I according to the detection signal in a time-sharing manner. ref , ensuring that the driving array detection unit 106 electrically connected to the column driving unit 103 accurately detects the driving performance of each driving unit 103 .

[0038] Optional, Figure 3 A schematic diagram of the structure of another microfluidic chip provided in an embodiment of the present invention is shown in FIG. Figure 1 and Figure 3 As shown, the drive array detection unit 106 includes a first switch transistor 1061 and a detection circuit 1062; the first electrode of the first switch transistor 1061 is electrically connected to the data signal line 104, the second electrode of the first switch transistor 1061 is electrically connected to the receiving end of the detection circuit 1062, and the gate of the first switch transistor 1061 is electrically connected to the first enable signal terminal SN1, and the first enable signal terminal SN1 is used to provide a first enable signal to the first switch transistor 1061 in the second detection stage; the detection circuit 1062 is configured to collect the drive current I output by each drive unit 103 in the drive unit column 1021 according to the detection signal after the first switch transistor 1061 is turned on. ref .

[0039] The drive array detection unit 106 includes a first switch transistor 1061 and a detection circuit 1062. The first switch transistor 1061 is electrically connected to a data signal line 104 and a detection circuit 1062 respectively. The first switch transistor 1061 is turned off in the first detection phase, and the first switch transistor 1061 is turned on in the second detection phase. The corresponding data signal line 104 is connected to the drive array detection unit 106, so that the drive current I output by the drive unit 103 through the data signal line 104 is ref can be received by the drive array detection unit 106, so that the drive array detection unit 106 can detect the driving current I ref The driving effectiveness of the driving unit 103 can be judged.

[0040] Optional, continue to refer to Figure 1 and Figure 3, the first switch transistors 1061 electrically connected to different data signal lines 104 are turned on in time-sharing mode. Since the microfluidic chip 101 includes a plurality of data signal lines 104, each data signal line 104 is electrically connected to a corresponding first switch transistor 1061, and the first switch transistor 1061 is electrically connected to a corresponding drive array detection unit 106, the first switch transistors 1061 electrically connected to different data signal lines 104 are controlled to be turned on in time-sharing mode, thereby enabling each drive array detection unit 106 to start working in time-sharing mode, and the drive array detection unit 106 can accurately detect each drive unit 103 in the drive unit column 1021, thereby ensuring the accuracy of the drive array detection unit 106.

[0041] Optional, Figure 4 A schematic diagram of the structure of another microfluidic chip provided in an embodiment of the present invention is shown in FIG. Figure 4 As shown, the detection circuit 1062 includes a first transistor T1 and a second transistor T2, a first electrode of the first transistor T1, a gate of the first transistor T1 and a gate of the second transistor T2 are electrically connected, a second electrode of the first transistor T1 and a second electrode of the second transistor T2 are grounded GND, a first electrode of the first transistor T1 is electrically connected to a second electrode of the first switch transistor 1061, and a first electrode of the second transistor T2 receives a driving current I according to the first electrode of the first transistor T1. ref And generate mirror current I copy .

[0042] The first electrode of the first transistor T1 in the detection circuit 1062 is electrically connected to the data signal line 104 via the first switch transistor 1061, the gate of the first transistor T1 is connected to the gate of the second transistor T2, the gate potentials of the first transistor T1 and the second transistor T2 are the same, the first electrode of the first transistor T1 is electrically connected to the gate of the first transistor T1, the second electrode of the first transistor T1 and the second electrode of the second transistor T2 are both grounded GND, and at this time, the detection circuit 1062 forms a current mirror circuit, which can receive the driving current I ref Can be mirrored to the first electrode of the second transistor T2 to form a mirror current I copy In the second detection phase, the first switch transistor 1061 is turned on, and the driving unit 103 outputs a driving current I according to the detection signal. ref flows through the first electrode of the first transistor T1, and at the same time generates a mirror current I at the first electrode of the second transistor T2 copy , the drive array detection unit 106 can be based on the mirror current I copy Determine the driving performance of the driving unit 103. Use the mirror current I generated by the second transistor T2 copy The first transistor T1 receives the driving current I refBy performing analysis and judgment, it is possible to reduce the interference of the detection process on the normal driving stage of the driving unit 103 and ensure the normal operation of the microfluidic chip 101.

[0043] Optionally, Figure 5 FIG. is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 5 shown, along the row direction X, the first poles of the second transistors T2 are electrically connected. Since the microfluidic chip 101 includes a plurality of detection circuits 1062, the second poles of the second transistors T2 in each detection circuit 1062 are electrically connected, reducing the number of mirror current Icopy transmission signal lines provided for the driving array detection unit 106. By providing one mirror current I copy transmission signal line, it is possible to judge the driving performance of each driving unit 103 in the driving array 102, reducing the setting difficulty and cost of the driving array detection unit 106.

[0044] Optionally, the channel width of the first transistor T1 is W1, and the channel length is L1; the channel width of the second transistor T2 is W2, and the channel length is L2; wherein, W2 / L2 = nW1 / L1, n≥1. When the ratio of the channel width to the channel length of the first transistor T1 is the same as the ratio of the channel width to the channel length of the second transistor T2, the driving current I ref received by the first pole of the first transistor T1 is copy equal to the mirror current I copy output at the first pole of the second transistor T2. At this time, the mirror current I ref can directly reflect the driving performance of the driving unit 103. When the ratio of the channel width to the channel length of the second transistor T2 is n times the ratio of the channel width to the channel length of the first transistor T1, the driving current I copy received by the first pole of the second transistor T2 is also n times the mirror current I copy output at the first pole of the first transistor T1. At this time, the mirror current I

[0045] Optionally, Figure 6 FIG. is a schematic diagram of a detection signal provided by an embodiment of the present invention. Figure 7 FIG. is another schematic diagram of a detection signal provided by an embodiment of the present invention. As Figure 6 and Figure 7As shown, at least two adjacent driving units 103 are included in the same column of driving units 103. The two adjacent driving units 103 include the i-th driving unit 103 and the (i + 1)-th driving unit 103, and the i-th driving unit 103 and the (i + 1)-th driving unit 103 receive different detection signals, where i≥1 and i is an integer.

[0046] Among them, Figure 6 and Figure 7 exemplarily show providing detection signals to each driving unit 103 in the 3×3 driving array 102. Different detection signals can be written in adjacent driving units 103 in the same column, and the same detection signal can be written in each driving unit 103 in adjacent columns. The different detection signals can be voltage signals with opposite polarities or voltage signals with a certain voltage difference. Exemplarily, as Figures 1 - 5 shown, a positive detection signal, such as 10V, can be written to the i-th driving unit 103 in the same column, and a negative detection signal, such as -10V, can be written to the (i + 1)-th driving unit 103. In the second detection stage, if the driving capabilities of all driving units 103 are effective, the driving array detection unit 106 can detect that the driving current I Figure 6 output by the i-th driving unit 103 is a positive current, and the driving current I ref output by the (i + 1)-th driving unit 103 is a negative current. At this time, the signal directions output by adjacent driving units 103 are opposite. Or exemplarily, as ref shown, a 10V detection signal can be written to the i-th driving unit 103 in the same column, and a 40V detection signal can be written to the (i + 1)-th driving unit 103. In the second detection stage, if the driving capabilities of all driving units 103 are effective, the driving array detection unit 106 can detect a difference between the driving current I Figure 7 output by the i-th driving unit 103 and the driving current I ref output by the (i + 1)-th driving unit 103. At this time, there is an obvious difference in the signal amplitudes output by adjacent driving units 103. Furthermore, the driving capabilities of the driving units 103 can be accurately detected by the opposite directions or amplitude differences of the signals output by adjacent driving units 103 in each column. In addition, ref shown in Figure 8 is another schematic diagram of the detection signal provided by the embodiment of the present invention, Figure 9 shown in Figure 8 and Figure 9 is another schematic diagram of the detection signal provided by the embodiment of the present invention. As shown in Figure 8 and Figure 9 , different detection signals can be written to adjacent driving units 103 in the same row to ensure the accurate detection of the driving capabilities of each driving unit 103 by the driving array detection unit 106 and reduce the interference risk.

[0047] Optionally, Figure 10 FIG. shows a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 10 shown, the detection signal input unit 105 includes a second switching transistor 1051. A first pole of the second switching transistor 1051 is electrically connected to the data signal line 104. A second pole of the second switching transistor 1051 is electrically connected to the detection signal input terminal S1. The detection signal input terminal S1 is used to provide a detection signal. A gate of the second switching transistor 1051 is electrically connected to the second enable signal terminal SN2. The second enable signal terminal SN2 is used to provide a second enable signal for the second switching transistor 1051 in the first detection stage.

[0048] Among them, the detection signal input unit 105 includes a second switching transistor 1051. Each data signal line 104 is correspondingly provided with a second switching transistor 1051. The second switching transistor 1051 is closer to the driving array 102 than the first switching transistor 1061 to ensure that the conduction stages of the detection signal input unit 105 and the driving array detection unit 106 do not interfere with each other. The second switching transistor 1051 conducts in the first detection stage, and writes the detection signal provided by the detection signal input terminal S1 into the driving unit 103 corresponding to the data signal line 104 and the scanning signal line 107 through the second switching transistor 1051, so as to ensure that the subsequent driving array detection unit 106 detects and judges the driving ability of each driving unit 103.

[0049] Optionally, Figure 11 FIG. shows a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 11 shown, two adjacent columns of data signal lines 104 include the j-th column data signal line 104 and the (j + 1)-th column data signal line 104. A gate of the first switching transistor 1061 electrically connected to the j-th column data signal line 104 and a gate of the second transistor T2 electrically connected to the (j + 1)-th column data signal line 104 are electrically connected, where j≥1 and j is an integer.

[0050] Among them, when the first switching transistor 1061 in the driving array detection unit 106 corresponding to the j-th column data signal line 104 conducts, the detection signal writing unit corresponding to the (j + 1)-th column data signal line 104 can be made to conduct simultaneously, and a detection signal is written into each driving unit 103 corresponding to the (j + 1)-th column data signal line 104, that is, the gate of the first switching transistor 1061 electrically connected to the j-th column data signal line 104 and the gate of the second transistor T2 electrically connected to the (j + 1)-th column data signal line 104 are electrically connected. Exemplarily, as Figure 11As shown in the figure, the gate of the first switching transistor 1061 electrically connected to the first column data signal line 104 is electrically connected to the gate of the second transistor T2 electrically connected to the second column data signal line 104, and the gate of the first switching transistor 1061 electrically connected to the second column data signal line 104 is electrically connected to the gate of the second transistor T2 electrically connected to the third column data signal line 104. At this time, the first switching transistor 1061 and the second transistor T2 need to be both P-type transistors or N-type transistors to ensure that they can be turned on or off simultaneously, saving the setting of the enable signal line and reducing the manufacturing difficulty and cost of the microfluidic chip 101.

[0051] Optionally, Figure 12 is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 12 shown, the microfluidic chip 101 further includes a plurality of data signal writing units 108; the data signal writing units 108 are electrically connected to the data signal lines 104; the data signal writing units 108 are configured to transmit data signals to the driving unit 103 during the working stage of the microfluidic chip.

[0052] Among them, to ensure that the microfluidic chip 101 can work properly during the non-detection stage, a plurality of data signal writing units 108 are provided in the microfluidic chip 101. One data signal writing unit 108 corresponds to one data signal line 104. The data signal writing unit 108 is turned on during the working stage of the microfluidic chip. With the time-sharing conduction of the scanning signal line 107, the data signal can be written into the corresponding driving unit 103 through the data signal writing unit 108, so as to ensure that the driving unit 103 provides a driving voltage for the driving electrode, and then realize the driving of the droplet.

[0053] Specifically, Figure 13 is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 13 shown, the data signal writing unit 108 includes a third switching transistor 1081. The first pole of the third switching transistor 1081 is electrically connected to the data signal line 104, the second pole of the third switching transistor 1081 is electrically connected to the data signal terminal S2, the data signal terminal S2 is used to provide data signals, and the gate of the third switching transistor 1081 is electrically connected to the third enable signal terminal SN3. The third enable signal terminal SN3 is used to provide a third enable signal for the third switching transistor 1081 during the working stage of the microfluidic chip.

[0054] Among them, the data signal writing unit 108 includes a third switching transistor 1081. Each data signal line 104 is correspondingly provided with a third switching transistor 1081. The third switching transistor 1081 is turned on during the operation stage of the microfluidic chip, and the data signal provided by the data signal terminal S2 is written into the data unit corresponding to the data signal line 104 and the scan signal line 107 through the third switching transistor 1081, ensuring that the driving unit 103 provides a driving voltage for the driving electrode, and then realizing the driving of the droplet.

[0055] Optionally, Figure 14 is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 14 shown, along the row direction X, the gates of the third switching transistors 1081 are electrically connected to the same third enable signal terminal SN3.

[0056] Among them, during the operation stage of the microfluidic chip, the gates of the third switching transistors 1081 in each data signal writing unit 108 can be electrically connected to the same third enable signal terminal SN3, so that the third switching transistors 1081 can be turned on simultaneously, ensuring that the data signals can be written into each data signal line 104 simultaneously. Combined with the time-division conduction of the scan signal line 107, the efficiency of writing the driving signal into the data signal is effectively improved, and the number of enable signal terminals can be reduced, reducing the manufacturing difficulty and manufacturing cost.

[0057] Optionally, Figure 15 is a schematic structural diagram of another microfluidic chip provided by an embodiment of the present invention. As Figure 15 shown, during the operation stage of the microfluidic chip, the detection signal input unit 105 is multiplexed as the data signal writing unit 108.

[0058] Among them, to further reduce the number of transistors, during the operation stage of the microfluidic chip, the detection signal input unit 105 can be multiplexed as the data signal writing unit 108, and the detection signal input unit 105 is used for data signal transmission. The second switching transistor 1051 in the detection signal input unit 105 is turned on, and the second enable signal terminal SN2 accesses the data signal, thereby ensuring that during the operation stage of the microfluidic chip, data signals can be output to each driving unit 103, and during the first detection stage, the second switching transistor 1051 in the detection signal input unit 105 is turned on, and the second enable signal terminal SN2 accesses the detection signal, reducing the manufacturing difficulty and manufacturing cost of the microfluidic chip 101.

[0059] Based on the same inventive concept, an embodiment of the present invention further provides a microfluidic device, which includes the microfluidic chip described in the above embodiment. The microfluidic device further includes a driving chip disposed on the microfluidic chip. By burning the corresponding driving program into the driving chip, the driving chip provides a driving signal to the microfluidic chip based on the burned program to drive the movement of droplets on the microfluidic chip. The microfluidic device is generally applied in many fields such as biomedical research, drug synthesis and screening, environmental monitoring and protection, health quarantine, forensic identification, detection of biological reagents, etc.

[0060] It should be noted that since the microfluidic device provided in this embodiment has the same or corresponding beneficial effects as the microfluidic chip of the above embodiment, it will not be elaborated here.

[0061] The above specific implementation manners do not constitute a limitation to the protection scope of the present invention. Those skilled in the art should understand that various modifications, combinations, sub-combinations and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A microfluidic chip, characterized in that, Comprising: A driving array, the driving array including a plurality of driving units arranged in an array; A plurality of data signal lines, the data signal lines extending in the column direction, the data signal lines being electrically connected to one column of the driving units; A plurality of detection signal input units, the detection signal input units being electrically connected to the data signal lines; A plurality of driving array detection units, the driving array detection units being electrically connected to the data signal lines; The detection signal input unit is configured to transmit a detection signal to the driving unit in a first detection stage; The driving array detection unit is configured to, after the first detection stage is completed, start working and collect the driving currents output by each of the driving units in the driving unit column according to the detection signal in a second detection stage.

2. The microfluidic chip according to claim 1, wherein The driving array detection unit includes a first switching transistor and a detection circuit; A first pole of the first switching transistor is electrically connected to the data signal line, a second pole of the first switching transistor is electrically connected to a receiving end of the detection circuit, a gate of the first switching transistor is electrically connected to a first enabling signal terminal, and the first enabling signal terminal is configured to provide a first enabling signal for the first switching transistor in the second detection stage; The detection circuit is configured to collect the driving currents output by each of the driving units in the driving unit column according to the detection signal after the first switching transistor is turned on.

3. The microfluidic chip according to claim 2, wherein, The first switching transistors electrically connected to different data signal lines are turned on in a time-sharing manner.

4. The microfluidic chip according to claim 2, wherein, The detection circuit includes a first transistor and a second transistor, a first pole of the first transistor, a gate of the first transistor and a gate of the second transistor are electrically connected, a second pole of the first transistor and a second pole of the second transistor are grounded, the first pole of the first transistor is electrically connected to the second pole of the first switching transistor, and the first pole of the second transistor generates a mirror current according to the driving current received by the first pole of the first transistor.

5. The microfluidic chip according to claim 3, characterized in that, In the row direction, the first poles of the second transistors are electrically connected.

6. The microfluidic chip according to claim 3, characterized in that, The channel width of the first transistor is W1, and the channel length is L1; the channel width of the second transistor is W2, and the channel length is L2; wherein, W2 / L2 = nW1 / L1, n≥1.

7. The microfluidic chip according to claim 1, characterized in that, At least two adjacent driving units are included in the same column of the driving units, the two adjacent driving units include an i-th driving unit and an (i + 1)-th driving unit, the i-th driving unit and the (i + 1)-th driving unit receive different detection signals, wherein, i≥1 and i is an integer.

8. The microfluidic chip according to claim 2, characterized in that, The detection signal input unit includes a second switching transistor, a first pole of the second switching transistor is electrically connected to the data signal line, a second pole of the second switching transistor is electrically connected to a detection signal input terminal, the detection signal input terminal is configured to provide a detection signal, a gate of the second switching transistor is electrically connected to a second enabling signal terminal, and the second enabling signal terminal is configured to provide a second enabling signal for the second switching transistor in the first detection stage.

9. The microfluidic chip according to claim 8, characterized in that, Two adjacent columns of data signal lines include the j-th column data signal line and the (j + 1)-th column data signal line. The gate of the first switching transistor electrically connected to the j-th column data signal line and the gate of the second transistor electrically connected to the (j + 1)-th column data signal line are electrically connected, where j ≥ 1 and j is an integer.

10. The microfluidic chip according to claim 1, wherein, The microfluidic chip further includes a plurality of data signal writing units; the data signal writing units are electrically connected to the data signal lines; The data signal writing units are configured to transmit data signals to the driving units during the operation stage of the microfluidic chip.

11. The microfluidic chip according to claim 10, characterized in that, The data signal writing unit includes a third switching transistor. A first pole of the third switching transistor is electrically connected to the data signal line. A second pole of the third switching transistor is electrically connected to a data signal terminal for providing a data signal. A gate of the third switching transistor is electrically connected to a third enabling signal terminal for providing a third enabling signal to the third switching transistor during the operation stage of the microfluidic chip.

12. The microfluidic chip according to claim 11, characterized in that, In the row direction, the gates of the third switching transistors are electrically connected to the same third enabling signal terminal.

13. The microfluidic chip according to claim 10, wherein, During the operation stage of the microfluidic chip, the detection signal input unit is multiplexed as the data signal writing unit.

14. The microfluidic chip according to claim 1, wherein The microfluidic chip further includes a plurality of scan signal lines extending in the row direction, and the scan signal lines are electrically connected to one row of the driving units; The driving unit includes a driving transistor and a capacitor; A first pole of the driving transistor is electrically connected to the data signal line. A second pole of the driving transistor is electrically connected to a first electrode plate of the capacitor. A gate of the driving transistor is electrically connected to the scan signal line. A second electrode plate of the capacitor is connected to a common voltage signal.

15. A microfluidic device, characterized in that, The microfluidic device includes the microfluidic chip according to any one of claims 1-14.

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