Rotatable platelet-rich plasma centrifugal preparation device

Abstract

The rotatable platelet-rich plasma centrifugal preparation device comprises a centrifugal tube, a rotating head and a connecting pipeline, the rotating head is contained in the centrifugal tube, one end of the rotating head is connected with the inlet and outlet end of the centrifugal tube through the connecting pipeline, and the other end of the rotating head is connected with the outlet and inlet end of the centrifugal tube. The other end of the rotating head is connected with a liquid extraction device through a connecting pipeline, and one end of the rotating head is rotatably connected with the other end of the rotating head. According to the rotatable centrifugal preparation device for the platelet-rich plasma, the rotating head is arranged in the centrifugal tube, the stress part relative to the rotating assembly is adjusted to the position of the center tube with higher strength, the hose which is most prone to losing efficacy originally only plays a connecting role after being adjusted and is not subjected to the torsion action any more, and the failure risk point in the prior art is effectively avoided.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and particularly to a rotatable platelet-rich plasma centrifugal preparation device for separating whole blood to obtain platelet-rich plasma or other blood components with a desired concentration. Background Art

[0002] The structural composition of existing horizontal centrifugal container products of the same type is relatively complex. They are usually composed of two centrifugal chambers, an intermediate partition block, dry / branch pipes, and three-way joints, etc. The intermediate block also needs to be equipped with an exhaust valve for connecting the two centrifugal chambers and a guiding channel for the dry pipeline to pass through. During installation, the dry pipeline needs to be passed through the commutation holes on the rotating base and the chuck first, then the centrifugal container is installed on the chuck of the rotating base, the pipelines in other parts are installed in the corresponding buckles, then the syringe is connected to the tubular joint and finally installed on the driving device. During the centrifugation process, the centrifugal container and the pipeline need to form differential rotation to remove the torsional moment brought by the rotation of the pipeline, so as to achieve the continuous rotation centrifugal function.

[0003] In the actual use process, the horizontal container structure of the existing rotatable platelet-rich plasma centrifugal preparation device is relatively complex; due to the rotation principle, the installation process of the centrifugal components is relatively complex. The connecting hose between the centrifugal container and the tubular joint is the main stress component, and the forces it bears mainly include the torsion force generated by differential rotation and acceleration and the centrifugal force generated by rotation, which poses a great test to the performance of the hose itself and the connection performance. And the existing products only provide two syringes for sucking blood. During use, the large-capacity syringe is used for injecting whole blood and sucking PPP / red blood cell layer, and the small-capacity syringe is used for sucking and injecting PRP, which does not meet the multi-component separation requirements. Summary of the Invention

[0004] Aiming at the problems existing in the prior art, the purpose of the present invention is to provide a rotatable platelet-rich plasma centrifugal preparation device with a simple structure, convenient installation, and capable of meeting multi-component separation.

[0005] To achieve the above object, the present invention provides a rotatable platelet-rich plasma centrifugal preparation device, including a centrifuge tube, a rotating head, and a connecting pipeline. The rotating head is accommodated in the centrifuge tube. One end of the rotating head is connected to the inlet and outlet end of the centrifuge tube through the connecting pipeline, and the other end of the rotating head is connected to a liquid extraction device through the connecting pipeline. One end of the rotating head is rotatably connected relative to the other end.

[0006] Specifically, the centrifuge tube includes an intermediate block, a tube body, a liquid collection part, a connection part, and a ventilation part. The tube body is arranged at both ends of the intermediate block, the liquid collection part is arranged at both ends of the tube body, the connection part is arranged at the inlet and outlet end of the liquid collection part, and the ventilation part is arranged on the tube body. The tube body, the intermediate block, the liquid collection part, the connection part, and the ventilation part form a single cavity structure.

[0007] Specifically, the pipe body includes a left pipe body and a right pipe body, the left pipe body and the right pipe body are respectively arranged at both ends of the middle block, the liquid collecting part includes a left liquid collecting part and a right liquid collecting part, the left liquid collecting part and the right liquid collecting part are respectively arranged at both ends of the middle block, the connecting part includes a left connecting part and a right connecting part, the left connecting part and the right connecting part are respectively arranged at the inlet and outlet ends of the left liquid collecting part and the right liquid collecting part, the left connecting part is connected to one end of a tee through a pipeline, the right connecting part is connected to the other end of the tee through a pipeline, the third end of the tee is connected to the other end of the rotating head, and the ventilation part is arranged in the middle of the middle block.

[0008] Specifically, the middle block includes a first cavity and a second cavity, the first cavity and the second cavity are not connected to each other, the first cavity is used to accommodate the rotating head, and the second cavity is used to connect the left pipe body and the right pipe body.

[0009] Specifically, all or part of the liquid collecting part has an inner cavity structure with a diameter decreasing from large to small, the connecting part is fixedly connected to the small-diameter end of the liquid collecting part and is provided with an inner hole communicating with the liquid collecting part.

[0010] Specifically, the rotation axis of the inner hole of the connecting part is coaxial or parallel to the rotation axis of the pipe body.

[0011] Specifically, the rotation axis of the inner hole of the connecting part is perpendicular or set at other angles to the rotation axis of the pipe body.

[0012] Specifically, the rotating head includes a central pipe, a bearing, a pressing block, a fixed sealing gasket, a rotating sealing gasket, a fixing block and a screw. The bearing is sleeved on the central pipe, one end of the bearing abuts against the shaft shoulder of the central pipe, and the other end of the bearing abuts against the pressing block. A fixed sealing ring is arranged at the lower end of the pressing block for sealed connection between the pressing block and the inner wall of the middle block. A rotating sealing gasket is also arranged at the lower end of the central pipe for sealed connection between the central pipe, the pressing block and the sealing shell. The sealing shell can be fixedly connected to the first cavity of the middle block by means of threaded connection, bonding or welding, etc. The pressing block, the fixed sealing gasket, the rotating sealing gasket and the sealing shell together form the sealing cavity of the rotating head.

[0013] Specifically, the central pipe includes a mounting end, a first liquid outlet end and a second liquid outlet end. The mounting end is cooperatively connected with the fixing part. The first liquid outlet end is connected to the tee through a pipeline, and the second liquid outlet end communicates with the inner cavity of the sealing shell.

[0014] Specifically, at least two tees are connected in series in sequence at the other end of the rotating head, and one end or both ends of the tee are respectively connected to the liquid extraction device through connectors.

[0015] Compared with the prior art, the rotatable platelet-rich plasma centrifugation preparation device of the present invention has the following technical effects: 1. In the rotatable platelet-rich plasma centrifugation preparation device of the present invention, the rotating head is built into the centrifuge tube. During the rotating centrifugation process, the liquid extraction device remains stationary, greatly simplifying the structure of the centrifuge tube and the connecting pipeline. The force-bearing part of the relative rotating assembly is adjusted to the center tube with higher strength. After adjustment, the hose that was originally most likely to fail only plays a connecting role and is no longer subject to torsion, effectively avoiding the failure risk points of the prior art; 2. The centrifuge tube in the rotatable platelet-rich plasma centrifugation preparation device of the present invention has a single-chamber structure, with a simple structure, convenient assembly, and low production cost; 3. The rotatable platelet-rich plasma centrifugation preparation device of the present invention can be set to connect at least three pipelines to the liquid extraction device to achieve the classified storage of at least three blood components. Description of the Drawings

[0016] Figure 1 It is the front view of the rotatable platelet-rich plasma centrifugation preparation device in an embodiment of the present invention; Figure 2 It is the front view of the rotatable platelet-rich plasma centrifugation preparation device with the liquid extraction device removed in an embodiment of the present invention; Figure 3 It is Figure 2 the sectional view of; Figure 4 It is Figure 2 the three-dimensional view of No. 10 in; Figure 5 It is Figure 4 the top view of; Figure 6 It is Figure 5 the A-A sectional view of; Serial number: 1 - centrifuge tube, 10 - intermediate block, 101 - first cavity, 102 - second cavity, 103 - protrusion, 11 - tube body, 111 - left tube body, 112 - right tube body, 12 - liquid collection part, 121 - left liquid collection part, 122 - right liquid collection part, 13 - connection part, 131 - left connection part, 132 - right connection part, 14 - ventilation part, 15 - bacteriostatic part, 2 - rotating head, 21 - fixing part, 22 - center tube, 23 - bearing, 24 - pressing block, 25 - fixed sealing gasket, 26 - rotating sealing gasket, 27 - sealing shell, 28 - fixing block, 29 - screw, 221 - installation end, 222 - first liquid outlet end, 223 - second liquid outlet end, 3 - three-way joint, 4 - joint, 5 - connecting pipeline. Embodiment

[0017] To make the objectives, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. Apparently, the described embodiments are only a part rather than all of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art without making creative efforts based on the embodiments of the present invention fall within the scope protected by the present invention.

[0018] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "center", "lateral", "length", "width", "height", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "side", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation to the present invention.

[0019] In the description of the present invention, it should also be noted that unless otherwise clearly specified and defined, the terms "installed", "connected" and "coupled" should be construed broadly. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0020] As Figure 1 shown, the rotatable platelet-rich plasma centrifugation preparation device in a specific embodiment of the present invention includes a centrifuge tube 1, a rotating head 2 and a connecting pipeline 5. The rotating head 2 is accommodated in the centrifuge tube 1. The inlet and outlet ends of the centrifuge tube 1 are connected to one end of the rotating head 2 through the connecting pipeline 5. The other end of the rotating head 2 is fixedly connected to a liquid extraction device (not shown in the figure) through the connecting pipeline 5. In the present invention, one end of the rotating head 2 can rotate freely relative to the other end of the rotating head 2.

[0021] As Figures 1-3As shown in the figure, the centrifuge tube 1 in this embodiment includes an intermediate block 10, a tube body 11, a liquid collection part 12, a connection part 13, and a ventilation part 14. Specifically, the tube body 11 includes a left tube body 111 and a right tube body 112. The left tube body 111 and the right tube body 112 are respectively arranged at the left and right ends of the intermediate block 10. In this embodiment, the tube body 11 and the intermediate block 10 are fixedly connected, and the fixed connection method is one of bonding, welding, or snap connection. The liquid collection part 12 includes a left liquid collection part 121 and a right liquid collection part 122. The left liquid collection part 121 is arranged at the left end of the left tube body 11, and the right liquid collection part 122 is arranged at the right end of the right tube body 112. The connection part 13 includes a left connection part 131 and a right connection part 132. The left connection part 131 and the right connection part 132 are respectively arranged at the inlet and outlet ends of the left liquid collection part 121 and the right liquid collection part 122. The ventilation part 14 is arranged on the tube body 11. The left connection part 131 is connected to one end of a tee 3 through a connection pipeline 5, and the right connection part 132 is connected to the other end of the tee 3 through a connection pipeline 5. The third end of the tee 3 is connected to the other end of the rotating head 2. The intermediate block 10, the tube body 11, the liquid collection part 12, the connection part 13, and the ventilation part 14 of the centrifuge tube 1 in this embodiment form a single-chamber structure, which has a simple structure, good sealing performance, and is convenient for assembly and production.

[0022] Specifically, the inner diameter of the tube body 11 in this embodiment is constant. The inner diameter of the tube body 11 in the present invention can also gradually increase or decrease from the middle to both sides. The cross-section of the tube body 11 in this embodiment is circular. The cross-section of the tube body 11 in the present invention can also be elliptical or polygonal.

[0023] Specifically, the ventilation part 14 in this embodiment is arranged in the middle of the tube body 11.

[0024] Specifically, a bacteria-blocking member 15 is further arranged on the ventilation part 14 of the centrifuge tube 1 in this embodiment, which is used to prevent bacteria from entering the interior of the tube body 11 while allowing air to be exchanged.

[0025] Specifically, all or part of the liquid collection part 12 in this embodiment has an inner cavity structure with a diameter gradually decreasing from large to small. The connection part 13 is fixedly connected to the small-diameter end of the liquid collection part 12 and is provided with an inner hole communicating with the connection part.

[0026] Specifically, the rotation axis of the inner hole of the connection part 13 in this embodiment is coaxial or parallel to the rotation axis of the tube body 11. The rotation axis of the inner hole of the connection part 13 in the present invention can also be perpendicular to the rotation axis of the tube body 11 or arranged at other angles.

[0027] As Figure 3As shown in the figure, the rotating head 2 in this embodiment includes a central tube 22, a bearing 23, a pressing block 24, a fixed sealing washer 25, a rotating sealing washer 26, a sealing shell 27, a fixing block 28 and a screw 29. The bearing 23 is sleeved on the central tube 22. One end of the bearing 23 abuts against the shoulder of the central tube 22, and the other end of the bearing 23 abuts against the pressing block 24. The bearing 23 functions to support the central tube 22 and enable its smooth rotation. The pressing block 24 functions to press the bearing 23. A fixed sealing ring 25 is provided at the lower end of the pressing block 24 to achieve the sealed connection between the pressing block 24 and the inner wall of the intermediate block 10. A rotating sealing washer 26 is also provided at the lower end of the central tube 22 to achieve the sealed connection between the central tube 22, the pressing block 24 and the sealing shell 27. In this embodiment, the pressing block 24, the fixed sealing washer 25, the rotating sealing washer 26 and the sealing shell 27 together form the sealing cavity of the rotating head 2, so that the blood flowing through it is not polluted by the external environment.

[0028] The central tube 22 in this embodiment includes a mounting end 221, a first liquid outlet end 222 and a second liquid outlet end 223. The mounting end 221 is cooperatively connected with the fixing portion 21. The first liquid outlet end 222 is connected to the liquid extraction device through a connecting pipeline 5, a three-way joint 3 and a connector 4. The second liquid outlet end 223 is connected to the connecting portion 13 of the centrifuge tube 1 through the three-way joint 3.

[0029] As Figures 4-6 shown in the figure, the intermediate block 10 in this embodiment is internally provided with a first cavity 101, a second cavity 102 and a protrusion 103 with a stepped structure. The first cavity 101 is not communicated with the second cavity 102. The second cavity 102 is communicated with the tube body 11. The rotating head 2 is accommodated in the first cavity 101. The fixing block 28 is cooperatively engaged at a specific angle through the intermittently provided protrusion 102 and is supported by the screw 29 to provide a certain pre-tightening force, so that the entire rotating head 2 is fixed in the first cavity 101 of the intermediate block 10.

[0030] The fixing portion 21 in this embodiment is a polygonal structure. Correspondingly, the mounting end 221 on the central tube 22 cooperatively connected with the fixing portion 21 is provided with a polygonal inner hole structure to prevent rotation between the fixing portion 21 and the mounting end 221 during the centrifugal rotation process.

[0031] During use, the fixing part 21 is fixedly installed on the centrifugal device. The fixing part 21 and the central tube 22 are stationary, and the centrifuge tube 1 rotates with the centrifugal device. Since there is a rotating head 2 in the whole device, the centrifuge tube 1 connected to one end of the rotating head 2 and the connecting pipeline 5 rotate for centrifugation. The other end of the rotating head 2 is connected to the liquid extraction device and remains stationary. The rotating head 2 plays a role in connection and diversion while enabling the relative rotation of the pipelines at both ends, meeting the requirements of rotational centrifugation. Since the rotating head 2 is built into the centrifuge tube 1, the structure of the pipeline is greatly simplified. The stress-bearing part of the relative rotation assembly is adjusted to the central tube with higher strength. The originally most easily failed hose only plays a connecting role after adjustment and is no longer subject to torsional force, effectively avoiding the failure risk points of the prior art.

[0032] In this embodiment, one end of the rotating head 2 is connected to one end of the tee 3. The other end of the tee 3 is connected to the liquid extraction device through the connecting pipeline 5 and the connector 4. The third end of the tee 3 is connected to one end of another tee 3 through the connecting pipeline 5. The other end of the other tee 33 is connected to another connector 4 and another liquid extraction device through the connecting pipeline. The third end of the tee 3 is connected to another connector 4 and another liquid extraction device through the connecting pipeline 5; according to actual application needs, the present invention can also be serially provided with a fourth tee, a fifth tee, or even more tees to connect a fourth liquid extraction device, a fifth liquid extraction device, or even more liquid extraction devices to realize the classified storage of at least three blood components.

[0033] Specifically, the liquid extraction device in the present invention is a medical syringe, the connector 4 in the present invention is a standard Luer connector, and the connecting pipeline 5 in the present invention is a transparent hose.

[0034] The above is only the specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention can easily think of changes or substitutions, which should all be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope of the claims.

Claims

1. A rotatable platelet-rich plasma centrifugation preparation device, characterized in that It includes a centrifuge tube, a rotating head and a connecting pipeline. The rotating head is accommodated in the centrifuge tube. One end of the rotating head is connected to the inlet and outlet end of the centrifuge tube through the connecting pipeline, and the other end of the rotating head is connected to a liquid extraction device through the connecting pipeline. One end of the rotating head is rotatably connected to the other end.

2. The rotatable platelet-rich plasma centrifugation preparation device according to claim 1, wherein The centrifuge tube includes an intermediate block, a tube body, a liquid collection part, a connecting part and a ventilation part. The tube body is arranged at both ends of the intermediate block, the liquid collection part is arranged at both ends of the tube body, the connecting part is arranged at the inlet and outlet end of the liquid collection part, and the ventilation part is arranged on the intermediate block. The tube body, the intermediate block, the liquid collection part, the connecting part and the ventilation part form a single cavity structure.

3. The rotatable platelet-rich plasma centrifugation preparation device according to claim 2, wherein, The tube body includes a left tube body and a right tube body. The left tube body and the right tube body are respectively arranged at both ends of the intermediate block. The liquid collection part includes a left liquid collection part and a right liquid collection part. The left liquid collection part and the right liquid collection part are respectively arranged at both ends of the intermediate block. The connecting part includes a left connecting part and a right connecting part. The left connecting part and the right connecting part are respectively arranged at the inlet and outlet ends of the left liquid collection part and the right liquid collection part. The left connecting part is connected to one end of a tee through a pipeline, and the right connecting part is connected to the other end of the tee through a pipeline. The third end of the tee is connected to the other end of the rotating head. The ventilation part is arranged in the middle of the tube body.

4. The rotatable platelet-rich plasma centrifugation preparation device according to claim 3, wherein, The intermediate block includes a first cavity and a second cavity. The first cavity and the second cavity are not connected. The first cavity is used to accommodate the rotating head, and the second cavity is used to connect the left tube body and the right tube body.

5. The rotatable platelet-rich plasma centrifugation preparation device according to claim 2, wherein, All or part of the liquid collection part is an inner cavity structure with a diameter decreasing from large to small. The connecting part is fixedly connected to the small-diameter end of the liquid collection part and is provided with an inner hole communicating with the liquid collection part.

6. The rotatable platelet-rich plasma centrifugal preparation device according to claim 2, wherein, The rotation axis of the inner hole of the connecting part is coaxial or parallel to the rotation axis of the tube body.

7. The rotatable platelet-rich plasma centrifugation preparation device according to claim 2, wherein, The rotation axis of the inner hole of the connecting part is perpendicular or at other angles to the rotation axis of the tube body.

8. The rotatable platelet-rich plasma centrifugation preparation device according to claim 1, wherein, The rotating head includes a central tube, a bearing, a pressing block, a fixed sealing washer, a rotating sealing washer, a fixed block and a screw. The bearing is sleeved on the central tube. One end of the bearing abuts against the shoulder of the central tube, and the other end of the bearing abuts against the pressing block. A fixed sealing ring is arranged at the lower end of the pressing block for sealing connection between the pressing block and the inner wall of the intermediate block. A rotating sealing washer is also arranged at the lower end of the central tube for sealing connection between the central tube and the pressing block and the sealing shell. The pressing block, the fixed sealing washer, the rotating sealing washer and the sealing shell together form the sealing cavity of the rotating head.

9. The rotatable platelet-rich plasma centrifugation preparation device according to claim 8, wherein, The central tube includes a mounting end, a first liquid outlet end and a second liquid outlet end. The mounting end is cooperatively connected with the fixing part. The first liquid outlet end is connected to the tee through a pipeline, and the second liquid outlet end communicates with the inner cavity of the sealing shell.

10. The rotatable platelet-rich plasma centrifugal preparation device according to claim 9, characterized in that, At least two tees are connected in series in sequence at the other end of the rotating head. One end or both ends of the tee are respectively connected to the liquid extraction device through connectors.

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