Platelet concentration method and system based on gravity sedimentation

By calculating the velocity difference and acceleration change rate during gravity sedimentation, the platelet concentration boundary is dynamically identified, solving the problem of insufficient boundary identification accuracy in existing technologies and achieving efficient platelet enrichment and purity improvement.

CN120296288BActive Publication Date: 2026-04-10JIANGSU DAOHE RUISI BIOTECHNOLOGY CO LTD
View PDF 2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGSU DAOHE RUISI BIOTECHNOLOGY CO LTD
Filing Date
2025-04-09
Publication Date
2026-04-10

AI Technical Summary

Technical Problem

Existing platelet concentration methods based on gravity sedimentation lack the means to identify continuous dynamic changes during sedimentation, resulting in decreased boundary recognition accuracy, easy layer overlap and extraction area shift, making it difficult to achieve high purity and efficient platelet enrichment.

Method used

By acquiring the depth, volume, and time sampling frequency of each vertical path unit in the settling container, calculating the trend of velocity difference changes, screening the rate of acceleration change, determining the platelet concentration boundary position, and performing secondary micro-platelet concentration based on the fall response path unit sequence of the boundary area.

Benefits of technology

It enables real-time tracking of cell sedimentation behavior, enhances the dynamic response capability of boundary identification, improves the accuracy of platelet enrichment and the stability of path execution, and adapts to the requirements of variable sample characteristics and high standard purity.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120296288B_ABST
    Figure CN120296288B_ABST
Patent Text Reader

Abstract

The present application relates to the technical field of platelet concentration, in particular to a platelet concentration method and system based on gravity sedimentation, comprising the following steps: obtaining sedimentation path unit parameters and collecting speed difference values, screening staggered difference point and judging acceleration trend, extracting decreasing curvature difference to determine boundary, adjusting inclination angle to collect speed change rate and screen falling path, calculating vector to establish extraction path to obtain secondary concentration data. In the present application, by extracting sedimentation speed difference value and acceleration change trend, the layered boundary area is identified, the positioning accuracy of the concentration limit is improved, based on the inclination disturbance induced dynamic response, the path unit with outstanding speed rising rate is screened, the perception ability and layered clarity of the limit area are enhanced, with the help of speed vector direction and center position calculation, a stable linear extraction path is constructed, efficient recovery and focused extraction of trace platelets are realized, the precision, stability and reuse efficiency of platelet concentration are improved, and it is suitable for complex sample conditions.
Need to check novelty before this filing date? Find Prior Art

Citation Information

Patent Citations

  • Platelet state analysis method and device, electronic equipment and storage medium

    CN112683743A

  • Aggregated platelet detection method based on YOLOX improved algorithm

    CN114820490A