Optical meter axis movement detection device for constructing convex lens based on microfluidics

By setting a microfluidic array and droplets between the optical meter axis and the image sensor, and controlling the droplet position by voltage, the spot group area is reduced, the accuracy of optical meter axis movement detection is improved, and the problem of low detection accuracy in the prior art is solved.

CN120298642APending Publication Date: 2025-07-11MAXIC TECHNOLOGY CORPORATION
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Patent Information

Application Number
CN202410031370.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-01-09
Publication Date
2025-07-11

AI Technical Summary

Technical Problem

In the prior art, the detection accuracy of optical table axis movement detection is low, and the density of image sensors cannot be large, resulting in limited number of detection points and insufficient detection accuracy.

Method used

A microfluidic array is set up between the optical table axis and the image sensor. The microfluidic array includes droplets in the shape of a convex lens. The position of the droplets is adjusted by controlling the voltage of the microfluidic chip to converge or not to converge the light after laser diffraction, increasing the acquisition range and probability of characteristic points of the image sensor.

Benefits of technology

Through the cooperation of the microfluidic array and droplets, the area of the spot group is reduced, and the image sensor can collect more feature points, improving the accuracy of optical table axis movement detection.

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Abstract

The invention relates to an optical meter axis movement detection device for constructing a convex lens based on microfluidics, and relates to the field of microfluidics. The optical surface axis movement detection device for constructing the convex lens based on microfluidics comprises a microfluidics array, liquid drops and an image sensor, the micro-fluidic array comprises each micro-fluidic unit; the micro-fluidic unit comprises a first micro-fluidic chip; the liquid drop is located on the surface of the first micro-fluidic chip and is in a convex lens shape; the micro-fluidic array is arranged between the optical meter shaft and the image sensor; the direction of light rays diffracted by the laser irradiation optical surface axis points to the liquid drop from the first micro-fluidic chip; the image sensor is used for collecting a first gray level image before the optical meter shaft moves and a second gray level image after the optical meter shaft moves, and the first gray level image and the second gray level image are used for detecting movement information of the optical meter shaft. The objective of the invention is to solve the problem of low detection precision of optical watch axis movement detection at present.
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Description

Technical Field

[0001] This application relates to the field of microfluidics, and particularly to an optical watch axis movement detection device based on constructing a convex lens by microfluidics. Background Art

[0002] Currently, the detection principles of optical watch axes in electronic watches on the market are similar. The main principle is that a laser irradiates the optical watch axis, and a diffraction phenomenon occurs to generate numerous light spots. An image sensor with a fixed area and position (such as CMOS, CCD, etc.) collects the light spots to obtain a first grayscale image. After the optical watch axis rotates, the light spot group will move, and the image sensor collects it to obtain a second grayscale image. The two grayscale images are processed, and based on the same patterns in the first grayscale image and the second grayscale image, the moving direction and distance of the optical watch axis are inferred, and then fed back to the display interface visible to the user.

[0003] As Figure 1 shown, it is a schematic diagram of the movement detection principle of the optical watch axis. In fact, the image sensor does not move, and the light spot group moves. For ease of understanding, the coordinate system is switched, which is represented as the light spot group not moving and the image sensor moving. Figure 1 In, the laser irradiates the optical watch axis, and a light spot group is generated within the imaging range. The solid rectangular frame is the first grayscale image before the optical watch axis moves, and the dashed rectangular frame is the second grayscale image after the optical watch axis moves. The overlapping area of the first grayscale image and the second grayscale image is the area of the same pattern before and after the movement of the optical watch axis. The moving direction of the optical watch axis can be detected based on the first grayscale image and the second grayscale image.

[0004] It can be seen that being able to accurately judge the same pattern without misjudging it as the same pattern due to similar patterns is crucial for accurately detecting movement. Image sensors are relatively expensive and the density cannot be made very large, which determines that the number of detectable points in the prior art is limited. Usually, the pixel size of the image sensor is in the order of dozens of micrometers, and the number of pixels is in the order of dozens multiplied by dozens. If all these points are hit in a similar area, the detection accuracy is low. If more feature positions (i.e., positions with large changes such as the image edge, etc.) can be hit, the detection accuracy is high.

[0005] In summary, there is a problem of low detection accuracy in the current movement detection of optical watch axes. Summary of the Invention

[0006] This application provides an optical watch axis movement detection device based on constructing a convex lens by microfluidics to solve the problem of low detection accuracy in the current movement detection of optical watch axes.

[0007] An embodiment of this application provides an optical watch axis movement detection device based on constructing a convex lens by microfluidics, including a microfluidic array, droplets, and an image sensor;

[0008] The microfluidic array includes individual microfluidic units; the microfluidic unit includes a first microfluidic chip; the droplet is located on the surface of the first microfluidic chip, and the droplet is in the shape of a convex lens; the microfluidic array is arranged between the optical axis and the image sensor; the direction of the light diffracted by the laser irradiating the optical axis is from the first microfluidic chip towards the droplet;

[0009] The image sensor is used to collect a first grayscale image before the movement of the optical axis and a second grayscale image after the movement of the optical axis, wherein the first grayscale image and the second grayscale image are used to detect the movement information of the optical axis.

[0010] Optionally, the microfluidic unit includes six cuboids, and the six cuboids form a hollow cube. The droplet is located inside the hollow cube, and one of the cuboids is the first microfluidic chip.

[0011] Optionally, one of the six cuboids is a second microfluidic chip; the second microfluidic chip is adjacent to the first microfluidic chip; there is a gap between the first microfluidic chip and the second microfluidic chip;

[0012] The optical axis movement detection device for constructing a convex lens based on microfluidics further includes a control component;

[0013] The control component is used to control the first microfluidic chip not to be powered on and the second microfluidic chip not to be powered on, so that the droplet is located on the surface of the first microfluidic chip, and the light diffracted by the laser irradiating the optical axis passes through the droplet; or, control the first microfluidic chip not to be powered on and control the second microfluidic chip to be powered on, so that the droplet moves from the surface of the first microfluidic chip to the surface of the second microfluidic chip, and the light diffracted by the laser irradiating the optical axis does not pass through the droplet.

[0014] Optionally, the four cuboids among the six cuboids other than the first microfluidic chip and the second microfluidic chip are a third microfluidic chip, a fourth microfluidic chip, a fifth microfluidic chip, and a sixth microfluidic chip respectively; there are gaps between the six cuboids;

[0015] The control component is further used to control each of the six cuboids to be powered on or not to be powered on, so that the droplet moves to the surface of the first microfluidic chip.

[0016] Optionally, the control component is specifically configured to control each of the six cuboids to be energized or de-energized every preset time period, so as to move the droplet to the surface of the first microfluidic chip.

[0017] Optionally, the control component is specifically configured to uniformly control each microfluidic chip in each of the microfluidic units to be energized or de-energized.

[0018] Optionally, the control component is specifically configured to separately control each microfluidic chip in each of the microfluidic units to be energized or de-energized, control the first microfluidic chip in the microfluidic units within a preset range to be de-energized, control the second microfluidic chip in the microfluidic units within a preset range to be de-energized, control the first microfluidic chip in the microfluidic units outside the preset range in the microfluidic array to be de-energized, and control the second microfluidic chip in the microfluidic units outside the preset range in the microfluidic array to be energized.

[0019] Optionally, the size of the first microfluidic chip is smaller than the pixel size of the image sensor.

[0020] The above technical solutions provided by the embodiments of the present application have the following advantages compared with the prior art: In the embodiments of the present application, the optical axis movement detection device for constructing a convex lens based on microfluidics includes a microfluidic array, a droplet, and an image sensor. The microfluidic array includes each microfluidic unit, and the microfluidic unit includes a first microfluidic chip. The droplet is located on the surface of the first microfluidic chip, and the droplet is in the shape of a convex lens. The microfluidic array is arranged between the optical axis and the image sensor. The direction of the diffracted light after the laser irradiates the optical axis is from the first microfluidic chip to the droplet. The image sensor is used to collect a first grayscale image before the optical axis moves and a second grayscale image after the optical axis moves. Among them, the first grayscale image and the second grayscale image are used to detect the movement information of the optical axis. By arranging a microfluidic array between the optical axis and the image sensor in the present application, and there is a droplet in the shape of a convex lens on the surface of the first microfluidic chip in the microfluidic array, which is equivalent to adding a convex lens before imaging, making the monomer pattern generated after the laser irradiates the optical axis diffract smaller. The image sensor with a fixed area can collect a larger range of light spot groups, and the probability of collecting feature points will also increase greatly, thereby improving the detection accuracy of optical axis movement detection. The problem of low detection accuracy of current optical axis movement detection is solved. Description of the Drawings

[0021] The accompanying drawings here are incorporated into the specification and constitute a part of this specification, showing embodiments consistent with the present application and used together with the specification to explain the principles of the present application.

[0022] To more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, for those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0023] Figure 1 It is a schematic diagram of the moving detection principle of the optical table axis in the prior art;

[0024] Figure 2 It is a top view of the microfluidic array in the embodiment of the present application;

[0025] Figure 3 It is a cross-sectional view of a single microfluidic unit in the embodiment of the present application;

[0026] Figure 4 It is a schematic diagram of the moving detection principle of the optical table axis after adding the microfluidic array and droplets in the embodiment of the present application;

[0027] Figure 5 It is a cross-sectional view of a single microfluidic unit in a specific embodiment of the present application;

[0028] Figure 6 It is a schematic diagram of the position of the droplet when no voltage is applied to the first microfluidic chip and the second microfluidic chip;

[0029] Figure 7 It is a schematic diagram of the position of the droplet when no voltage is applied to the first microfluidic chip and voltage is applied to the second microfluidic chip. Specific Embodiments

[0030] To make the objectives, technical solutions, and advantages of the embodiments of the present application clearer, the following will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all of them. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present application without creative efforts belong to the scope of protection of the present application.

[0031] In the embodiments of the present application, an optical table axis movement detection device based on microfluidics to construct a convex lens is provided, including a microfluidic array, droplets, and an image sensor;

[0032] The microfluidic array includes each microfluidic unit; the microfluidic unit includes a first microfluidic chip; the droplet is located on the surface of the first microfluidic chip, and the droplet is in the shape of a convex lens; the microfluidic array is arranged between the optical table axis and the image sensor; the direction of the light diffracted by the laser irradiating the optical table axis is from the first microfluidic chip to the droplet;

[0033] The image sensor is used to collect a first grayscale image before the movement of the optical table axis and a second grayscale image after the movement of the optical table axis. The first grayscale image and the second grayscale image are used to detect the movement information of the optical table axis.

[0034] As Figure 2 shown, it is a top view of the microfluidic array. Figure 2 In it, the circles represent droplets and the squares represent microfluidic units. Figure 2 In it, the number of microfluidic units in the microfluidic array is only for illustration.

[0035] As Figure 3 shown, it is a cross-sectional view of a single microfluidic unit. Figure 3 In it, the solid line with an arrow is the actual irradiation path of the light diffracted by the laser irradiating the optical table axis passing through the first microfluidic chip and the droplet, and the dashed line with an arrow is the irradiation path of the light diffracted by the laser irradiating the optical table axis in the case without a droplet. Figure 3 In it, the direction of the light diffracted by the laser irradiating the optical table axis is from the first microfluidic chip to the droplet. The droplet is located on the surface of the first microfluidic chip and the droplet is in the shape of a convex lens. The droplet is located on the surface of the first microfluidic chip and is in the shape of a convex lens due to hydrophobicity, and will converge the received light to achieve the purpose of reducing the graphic area of the spot group.

[0036] Digital microfluidics is a technology based on the electrowetting effect to precisely control the generation, movement, and fusion of droplets. It has the advantages of high throughput, automation, less required reagent volume, rapid reaction, etc., and has been widely applied in DNA preparation, molecular diagnosis, immunoassay, drug analysis, chemical experiments, etc. Currently, droplets as small as nanoliter volume can be manipulated. Briefly speaking, the electrowetting effect is to change the wettability of the droplet by applying a voltage. When no voltage is applied, the droplet is located on the surface of the superhydrophobic material, the contact angle is very small, and it will present a state close to a sphere. After applying the voltage, the contact angle of the droplet becomes larger, causing a pressure difference inside the droplet, and then the droplet collapses to achieve the purpose of moving the droplet.

[0037] The droplet located on the superhydrophobic interface is a natural convex lens, and the entire microfluidic system is made of highly light-transmissive materials, with an overall light transmittance of over 95%. This means that digital microfluidics is a naturally excellent controllable lens. It can be used in existing optical systems, has a minimal impact on the light intensity, and can converge or diverge the light path at the same time. The requirements for optical systems in existing electronic devices are increasing day by day. They require small size, low cost, and high performance at the same time, and the requirement for precision is of the utmost importance. Using controllable microfluidics to assist the optical system can obtain higher precision at low cost and is flexible and controllable. Currently, no solution for using digital microfluidics to improve the precision of optical systems in electronic devices has been seen.

[0038] When no voltage is applied to the microfluidic chip, the droplet will remain approximately spherical when it is on the hydrophobic layer surface, which is equivalent to a convex lens. When a voltage is applied to the microfluidic chip, the electro-wetting effect will occur. Simply put, the hydrophobic layer becomes a hydrophilic layer and the droplet will collapse. Through the cooperation of two microfluidic chips, droplet transportation can be achieved. The smallest droplet can be in the picoliter range. The intermolecular force between the droplet and the microfluidic chip is greater than the weight of the droplet itself, so even if the droplet is placed vertically, it will not cause the droplet to flow down. The size of the droplet is in the micrometer range, and the micrometer-scale microfluidic chip can also be manufactured through existing display production lines or MEMS.

[0039] As Figure 4 shown, it is a schematic diagram of the moving detection principle of the optical axis after adding a microfluidic array and droplets in the embodiment of the present application. Actually, the image sensor does not move, and the spot group moves. For ease of understanding, the coordinate system is switched, which is manifested as the spot group not moving and the image sensor moving. Figure 4 In, a laser irradiates the optical axis, and a spot group is generated within the imaging range. The solid rectangular frame is the first grayscale image before the optical axis moves, and the dashed rectangular frame is the second grayscale image after the optical axis moves. The overlapping area of the first grayscale image and the second grayscale image is the same pattern area before and after the optical axis moves. The moving direction of the optical axis can be detected based on the first grayscale image and the second grayscale image. Compared with Figure 1 Figure 4 a microfluidic array is added. Figure 4 In, the droplet is not drawn. For the specific relationship between the microfluidic array and the droplet, see Figure 2 and Figure 3 . From Figure 1 and Figure 4 it can be seen that Figure 4 the graphic area of the spot group in has shrunk. After adding the microfluidic array, the convergence effect is default turned on, so the area of a single spot will decrease, and the area of the spot group will also decrease. More spots, that is, more feature points, can be included in the image sensor of the same area, thereby achieving an improvement in accuracy.

[0040] In a specific embodiment, the microfluidic unit includes 6 cuboids. The 6 cuboids form a hollow cube, and the droplet is located inside the hollow cube. Among them, 1 cuboid is the first microfluidic chip. As Figure 5 shown, it is a cross-sectional view of a single microfluidic unit in a specific embodiment of the present application. Since it is a cross-sectional view, Figure 5 only 4 cuboids are shown in. Figure 5 In, the droplet is located inside the hollow cube. The hollow cube structure can prevent the droplet from being thrown off due to excessive vibration amplitude of the electronic watch.

[0041] ​In a specific embodiment, one of the six cuboids is the second microfluidic chip; the second microfluidic chip is adjacent to the first microfluidic chip; there is a gap between the first microfluidic chip and the second microfluidic chip;

[0042] The optical axis movement detection device for constructing a convex lens based on microfluidics further includes a control component;

[0043] The control component is used to control the first microfluidic chip without applying voltage and the second microfluidic chip without applying voltage, so that the droplet is located on the surface of the first microfluidic chip, and the light diffracted by the laser illuminating the optical axis passes through the droplet; or, control the first microfluidic chip without applying voltage and control the second microfluidic chip to apply voltage, so that the droplet moves from the surface of the first microfluidic chip to the surface of the second microfluidic chip, and the light diffracted by the laser illuminating the optical axis does not pass through the droplet. As Figure 6 shown, it is a schematic diagram of the position of the droplet when the first microfluidic chip and the second microfluidic chip do not apply voltage. As Figure 7 shown, it is a schematic diagram of the position of the droplet when the first microfluidic chip does not apply voltage and the second microfluidic chip applies voltage.

[0044] When the first microfluidic chip and the second microfluidic chip do not apply voltage, the droplet is located on the surface of the first microfluidic chip. Due to hydrophobicity, it is in the shape of a convex lens and will converge the received light to achieve the purpose of reducing the area of the light spot pattern. When the first microfluidic chip does not apply voltage and the second microfluidic chip applies voltage, the droplet will climb to the surface of the second microfluidic chip due to the electrowetting effect and finally adhere to the surface of the second microfluidic chip. At this time, the light passing through the first microfluidic chip will not be affected. This provides a more flexible choice for the application of this solution, either using a convex lens or not using a convex lens.

[0045] In a specific embodiment, the other 4 cuboids among the 6 cuboids, except the first microfluidic chip and the second microfluidic chip, are the third microfluidic chip, the fourth microfluidic chip, the fifth microfluidic chip and the sixth microfluidic chip respectively; there are gaps between all 6 cuboids;

[0046] The control component is further used to control each of the 6 cuboids to apply voltage or not apply voltage, so that the droplet moves to the surface of the first microfluidic chip.

[0047] All 6 cuboids are microfluidic chips. When the droplet runs to the other 4 cuboids among the 6 cuboids except the first microfluidic chip and the second microfluidic chip due to excessive vibration, or breaks into small droplets and flies to the other 4 cuboids among the 6 cuboids except the first microfluidic chip and the second microfluidic chip, it is possible to control each of the 6 cuboids to apply voltage or not apply voltage, so that the droplet finally converges and moves to the surface of the first microfluidic chip.

[0048] In a specific embodiment, the control component is specifically configured to control each of the six cuboids to be energized or de-energized at preset time intervals, so as to move the droplets to the surface of the first microfluidic chip.

[0049] Regularly execute a fixed droplet recovery process to ensure that the droplets are located on the surface of the first microfluidic chip.

[0050] In a specific embodiment, the control component is specifically configured to uniformly control each microfluidic chip in each microfluidic unit to be energized or de-energized.

[0051] For example, uniformly control the first microfluidic chip and the second microfluidic chip in each microfluidic unit to be de-energized, or uniformly control the first microfluidic chip in each microfluidic unit to be de-energized and the second microfluidic chip to be energized.

[0052] In a specific embodiment, the control component is specifically configured to individually control each microfluidic chip in each microfluidic unit to be energized or de-energized, control the first microfluidic chip in the microfluidic units within a preset range to be de-energized, control the second microfluidic chip in the microfluidic units within a preset range to be de-energized, control the first microfluidic chip in the microfluidic units outside the preset range in the microfluidic array to be de-energized, and control the second microfluidic chip in the microfluidic units outside the preset range in the microfluidic array to be energized. The droplets in the microfluidic units within the preset range are located on the surface of the first microfluidic chip, and the droplets in the microfluidic units outside the preset range in the microfluidic array are located on the surface of the second microfluidic chip. The microfluidic units and droplets within the preset range play a role in local reduction.

[0053] In a specific embodiment, the size of the first microfluidic chip is smaller than the pixel size of the image sensor. Since the pixel corresponds to the light spot, and the size of the first microfluidic chip is smaller than the pixel size of the image sensor, the light spot is reduced in blocks by multiple convex lenses, and the light spot feature points can be reduced as evenly as possible.

[0054] In summary, in the present application, by arranging a microfluidic array between the optical axis and the image sensor, and there are droplets in the shape of convex lenses on the surface of the first microfluidic chip in the microfluidic array, which is equivalent to adding a convex lens before imaging, making the single pattern generated after the laser irradiates the optical axis diffract smaller. The image sensor with a fixed area can collect a larger range of light spot groups, and the probability of collecting feature points will also increase greatly, thereby improving the detection accuracy of optical axis movement detection. It solves the problem of low detection accuracy in current optical axis movement detection.

[0055] It should be noted that, in this text, relational terms such as "first" and "second" are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "comprising an..." does not exclude the presence of additional identical elements in the process, method, article or device comprising the said element.

[0056] The above are only specific embodiments of the present application, enabling those skilled in the art to understand or implement the present application. Various modifications to these embodiments will be obvious to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application will not be limited to these embodiments shown herein, but rather will conform to the broadest scope consistent with the principles and novel features claimed herein.

Claims

1. An optical spindle movement detection device based on constructing a convex lens by microfluidics, characterized in that It includes a microfluidic array, droplets, and an image sensor; The microfluidic array includes individual microfluidic units; each microfluidic unit includes a first microfluidic chip; the droplets are located on the surface of the first microfluidic chip, and the droplets are in the shape of a convex lens; the microfluidic array is arranged between the optical axis and the image sensor; the direction of the light diffracted by the laser irradiating the optical axis is from the first microfluidic chip towards the droplets; The image sensor is used to collect a first grayscale image before the optical axis moves and a second grayscale image after the optical axis moves, wherein the first grayscale image and the second grayscale image are used to detect the movement information of the optical axis.

2. The optical axis movement detection device for constructing a convex lens based on microfluidics according to claim 1, wherein The microfluidic unit includes 6 cuboids, and the 6 cuboids form a hollow cube. The droplets are located inside the hollow cube, and 1 cuboid is the first microfluidic chip.

3. The optical axis movement detection device for constructing a convex lens based on microfluidics according to claim 2, wherein 1 of the 6 cuboids is a second microfluidic chip; the second microfluidic chip is adjacent to the first microfluidic chip; there is a gap between the first microfluidic chip and the second microfluidic chip; The optical axis movement detection device for constructing a convex lens based on microfluidics further includes a control component; The control component is used to control the first microfluidic chip without applying voltage and control the second microfluidic chip without applying voltage, so that the droplets are located on the surface of the first microfluidic chip, and the light diffracted by the laser irradiating the optical axis passes through the droplets; or, control the first microfluidic chip without applying voltage and control the second microfluidic chip with applying voltage, so that the droplets move from the surface of the first microfluidic chip to the surface of the second microfluidic chip, and the light diffracted by the laser irradiating the optical axis does not pass through the droplets.

4. The optical axis movement detection device for constructing a convex lens based on microfluidics according to claim 3, characterized in that, The 4 cuboids among the 6 cuboids other than the first microfluidic chip and the second microfluidic chip are respectively the third microfluidic chip, the fourth microfluidic chip, the fifth microfluidic chip, and the sixth microfluidic chip; there are gaps between the 6 cuboids; The control component is further used to control each of the 6 cuboids to apply voltage or not apply voltage, so that the droplets move to the surface of the first microfluidic chip.

5. The optical spindle movement detection device based on a microfluidic convex lens according to claim 4, wherein Specifically, the control component is used to control each of the 6 cuboids to apply voltage or not apply voltage every preset time period, so that the droplets move to the surface of the first microfluidic chip.

6. The optical axis movement detection device for constructing a convex lens based on microfluidics according to claim 3, characterized in that, Specifically, the control component is used to uniformly control each microfluidic chip in each microfluidic unit to apply voltage or not apply voltage.

7. The optical axis movement detection device for constructing a convex lens based on microfluidics according to claim 3, characterized in that, The control component is specifically configured to individually control each microfluidic chip in each microfluidic unit to apply voltage or not, control the first microfluidic chip in the microfluidic units within a preset range not to apply voltage, control the second microfluidic chip in the microfluidic units within a preset range not to apply voltage, control the first microfluidic chip in the microfluidic units outside the preset range in the microfluidic array not to apply voltage, and control the second microfluidic chip in the microfluidic units outside the preset range in the microfluidic array to apply voltage.

8. The optical axis movement detection device for constructing a convex lens based on microfluidics according to any one of claims 1 to 7, characterized in that The size of the first microfluidic chip is smaller than the pixel size of the image sensor.