Living body sampling and inspecting device for oncology department

The biopsy device stabilizes on the skin, reduces contamination risk, and efficiently collects tumor tissue fluid and blocks simultaneously, improving diagnostic accuracy by maintaining vacuum during transport.

CN120304876AInactive Publication Date: 2025-07-15THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIV OF TRADITIONAL CHINESE MEDICINE (ZHEJIANG XINHUA HOSPITAL)
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510275656.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-10
Publication Date
2025-07-15
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing biopsy needles are difficult to stabilize on the patient's skin, which easily leads to a deviation of the puncture position, and it is difficult to sample tissue fluid and tissue blocks in the tumor at the same time, increasing the difficulty of operation and possibly introducing bacteria.

Method used

A live sampling and testing device for oncology is designed, which is fixed on the patient's skin through vacuum adsorption of the outer cylinder and the inner cylinder. The inner cylinder is equipped with a fixing block and a sealing member to ensure the vacuum state. The sampling and extraction mechanism combine to achieve the simultaneous acquisition of tissue fluid and tissue blocks, and the piston movement is controlled by a magnet to meet different sampling needs.

Benefits of technology

It realizes that the vacuum state is maintained during the sampling process, avoiding bacteria entering, reducing operation difficulty, and obtaining tissue fluid and tissue blocks at the same time, improving sampling efficiency and accuracy.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120304876A_ABST
    Figure CN120304876A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of medical instruments, in particular to an oncology department living body sampling and inspection device which comprises an outer cylinder, an inner cylinder is fixedly connected to the inner top face of the outer cylinder, a fixing block is fixedly connected to the bottom end of the inner wall of the inner cylinder, a through hole is formed in the top face of the fixing block in a penetrating mode, and a fixing mechanism is arranged in the inner cylinder. The blocking piece is arranged on the top face of the fixing block and used for blocking the through hole. The space between the outer cylinder and the inner cylinder is vacuumized, the outer cylinder can be adsorbed to the body of a patient, the fixing block makes contact with the skin of the patient, the puncture point is made to be a plane, the outer cylinder and the inner cylinder can be fixed to the body of the patient, and the inner cylinder can be vacuumized during needle inserting, tumor sample obtaining and needle withdrawing. And the inner cylinder is always in a vacuum state, so that germs in the air can be prevented from entering the body of a patient along with the needle tube.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and specifically relates to a living tissue sampling and inspection device for oncology. Background Art

[0002] Pathological examination of living tissue, abbreviated as biopsy, is an important method of taking living tissue for morphological examination to make a disease diagnosis. Biopsy is mainly used for the differentiation of tumors and non-tumor diseases, benign and malignant tumors, to judge the degree and scope of the growth, invasion, and metastasis of malignant tumors, and to observe the development degree of the disease or the therapeutic response, etc. It is the most important part of diagnostic pathology and can make a clear histopathological diagnosis for the vast majority of submitted cases, and is called the final clinical diagnosis.

[0003] Currently, when taking living tissue samples of tumors, a biopsy needle is usually used for puncture operation, and then the samples taken by puncture are sent to the inspection department for testing. When the existing biopsy needles are in use currently, it is difficult for the biopsy needle to be firmly fixed on the patient's skin, resulting in possible deviation of the puncture position. Moreover, before puncture, the biopsy needle is directly exposed, which is likely to bring germs in the air into the patient's body. And the existing biopsy needles sample the tissue fluid and tissue mass in the tumor separately, and it is difficult to sample the tissue fluid and tissue mass in the tumor simultaneously, which not only increases the sampling time of the tumor, but also increases the operation difficulty of medical staff (when sampling the tumor tissue mass, sampling is carried out through the core needle in the biopsy needle. When sampling the tissue fluid, the core needle needs to be withdrawn, and then a syringe is installed at one end of the needle tube. Especially when sampling superficial tumors, installing the syringe or withdrawing the core needle easily causes the needle tube to shake and the position of the needle tube to deviate. Therefore, installing the syringe and withdrawing the core needle will increase the operation difficulty of medical staff). Summary of the Invention

[0004] The purpose of the present invention is to provide a living tissue sampling and inspection device for oncology to solve the problems raised in the above background art.

[0005] To achieve the above purpose, the present invention provides the following technical solutions:

[0006] A living tissue sampling and inspection device for oncology, comprising:

[0007] An outer cylinder, the inner top surface of the outer cylinder is fixedly connected with an inner cylinder, the bottom end of the inner wall of the inner cylinder is fixedly connected with a fixed block, and a through hole is formed through the top surface of the fixed block;

[0008] A fixing mechanism, arranged inside the inner cylinder;

[0009] A plugging member, arranged on the top surface of the fixed block for plugging the through hole;

[0010] Sampling mechanism, which is arranged inside the inner cylinder and detachably connected inside the fixing mechanism, and is used for sampling inside the patient's tumor. The sampling mechanism includes a sleeve detachably connected inside the fixing mechanism. A syringe needle communicated with the inside of the sleeve is fixedly connected to the bottom end of the sleeve. A piston is slidably sleeved inside the sleeve. A core needle that penetrates and slides through the syringe needle is fixedly connected to the bottom end of the piston. A rubber ring is fixedly connected to the inner wall of the sleeve;

[0011] Extraction mechanism, which is arranged above the fixing mechanism and is used to control the sampling mechanism to pick up tissue fluid and tissue blocks inside the tumor.

[0012] Furthermore: The fixing mechanism includes a moving ring that slides inside the inner cylinder. A threaded ring is arranged inside the moving ring. A plurality of connecting rods are fixedly connected annularly and equiangularly between the threaded ring and the moving ring. A threaded groove that is screwed and connected with the threaded ring is opened at the top end of the outer wall of the sleeve.

[0013] Furthermore: The diameter of the through hole is larger than the diameter of the sleeve. A limiting ring is fixedly connected to the outer wall of the sleeve and below the threaded groove.

[0014] Furthermore: A multi-stage telescopic member is fixedly connected to the bottom surface of the moving ring. A cylindrical sleeve is fixedly connected to the bottom end of the multi-stage telescopic member. A steel ball is fixedly connected to the inner wall of the cylindrical sleeve. The plugging member includes a rotating shaft rotatably connected to the fixed block. A blocking block is fixedly connected to the outer wall of the rotating shaft. Two symmetrically arranged guide rails are fixedly connected to the outer wall of the rotating shaft, one above the other.

[0015] Furthermore: A threaded sleeve penetrates and rotates through the top surface of the outer cylinder. A first screw rod fixedly connected to the moving ring is screwed and connected inside the threaded sleeve. A first screwing block is fixedly connected to the top end of the threaded sleeve.

[0016] Furthermore: A fixed ring is fixedly connected to the inner wall of the inner cylinder and above the moving ring.

[0017] Furthermore: A fixed rod is fixedly connected to the top end of the piston. A pressing block is fixedly connected to the top end of the fixed rod. A first magnet is embedded and fixed at the top end of the pressing block. The extraction mechanism includes a round rod that penetrates and slides through the top surface of the outer cylinder. A cylindrical groove is opened at the bottom end of the round rod. A second screw rod penetrates and is screwed through the inner top surface of the cylindrical groove. A connecting block is rotatably connected to the bottom end of the second screw rod. A second magnet that attracts the first magnet is fixedly connected to the bottom end of the connecting block.

[0018] Furthermore: A plurality of limiting strips are fixedly connected annularly and equiangularly to the inner wall of the cylindrical groove. A limiting block is fixedly connected to the bottom end of the limiting strip. Embedding grooves are opened at the corresponding positions of the outer wall of the connecting block for the limiting strips. Limiting grooves are opened at the corresponding positions of the top surface of the pressing block for the limiting strips.

[0019] Furthermore, two symmetric limiting plates which are fixedly connected to the outer wall of the round rod and penetrate and slide through the top surface of the outer cylinder are provided.

[0020] Furthermore, two fixing seats inside the vehicle are fixedly connected to the top surface of the outer cylinder. The top end of the round rod is fixedly connected with a fixing plate. Two symmetric notches are formed in the outer wall of the fixing plate. Two symmetric locking pieces are arranged between the fixing plate and the outer cylinder. The locking piece includes a positioning rod clamped with the notch at the corresponding position. Positioning blocks are fixedly connected to both ends of the positioning rod. A slider penetrates and slides on the outer wall of the positioning rod. A spring is fixedly connected between the slider and the lower positioning block. The bottom end of the lower positioning block is fixedly connected with a rotating block rotatably connected to the fixing seat at the corresponding position.

[0021] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0022] 1. By evacuating the space between the outer cylinder and the inner cylinder, the outer cylinder can be adsorbed on the patient's body, and the fixing block contacts the patient's skin, so that the puncture point is a plane, and the outer cylinder and the inner cylinder can be fixed on the patient's body. Moreover, by evacuating the inner cylinder, the inner cylinder is always in a vacuum state during needle insertion, tumor sample acquisition, and needle withdrawal, so as to prevent germs in the air from entering the patient's body along the needle tube.

[0023] 2. Since the plugging member blocks the through hole after the needle tube is retracted into the inner cylinder, and the outer cylinder is still adsorbed on the patient's body, when the outer cylinder is pulled away from the patient's body, the inner cylinder is still in a vacuum state. Therefore, during the specimen submission process, the obtained sample is still in a vacuum environment, so as to prevent the sample from being contaminated by the external environment during specimen submission.

[0024] 3. By controlling the movement of the piston through the round rod, the simultaneous acquisition of tissue blocks and tissue fluid can be realized, so that the testing personnel can detect the tissue blocks and tissue fluid. Then, through the combination of the two, the determination of the tumor nature can be increased. And by controlling the separation of the second magnet from the first magnet through the second screw rod, the required tissue fluid or tissue block can be obtained according to the actual situation, thereby improving the universality of the device.

[0025] 4. By erecting the positioning rod and placing the positioning rod in the notch at the corresponding position, and then making the slider closely contact the bottom surface of the fixing plate through the spring, the round rod can be supported, preventing the round rod from colliding with the pressing block under its own gravity, which may cause the piston to drive the core needle to move and contact the blocking block, resulting in the breakage of the core needle. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is a schematic diagram of the overall structure of the present invention;

[0027] Figure 2It is a schematic diagram of the internal structures of the outer cylinder and the inner cylinder in the present invention;

[0028] Figure 3 It is a sectional view of the outer cylinder and the inner cylinder in the present invention;

[0029] Figure 4 It is a schematic diagram of the structure of the fixing mechanism in the present invention;

[0030] Figure 5 It is a schematic diagram of the structure of the plugging member in the present invention;

[0031] Figure 6 It is a schematic diagram of the structure of the sampling mechanism in the present invention;

[0032] Figure 7 It is a schematic diagram of the structure of the extraction mechanism in the present invention;

[0033] Figure 8 It is a schematic diagram of the round rod and the second screw in the present invention;

[0034] Figure 9 It is an enlarged view at position A in the present invention;

[0035] Figure 10 It is a schematic diagram of the structure of the locking member in the present invention.

[0036] In the figure: 1. Outer cylinder; 11. Inner cylinder; 12. Fixed block; 13. Fixed ring; 14. Fixed seat; 2. Fixing mechanism; 21. Moving ring; 22. Threaded ring; 23. Connecting rod; 24. Multi-stage telescopic member; 25. Cylindrical sleeve; 26. Threaded sleeve; 27. First screw; 3. Plugging member; 31. Rotating shaft; 32. Plug block; 33. Guide rail; 4. Sampling mechanism; 41. Sleeve; 42. Syringe needle; 43. Threaded groove; 44. Piston; 45. Core needle; 46. Fixed rod; 47. Pressing block; 48. First magnet; 49. Limiting ring; 5. Extraction mechanism; 51. Round rod; 511. Limiting strip; 512. Limiting block; 513. Limiting plate; 52. Second screw; 521. Connecting block; 522. Second magnet; 53. Fixed plate; 531. Notch; 54. Locking member; 541. Positioning rod; 542. Positioning block; 543. Slide block; 544. Spring; 545. Rotating block. Detailed implementation manners

[0037] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0038] Please refer to Figure 1 - Figure 10, in an embodiment of the present invention, a living body sampling and submission device for oncology department includes an outer cylinder 1. The inner top surface of the outer cylinder 1 is fixedly connected with an inner cylinder 11. The bottom end of the inner wall of the inner cylinder 11 is fixedly connected with a fixing block 12. A through hole is formed through the top surface of the fixing block 12. A first trachea is fixedly penetrated through the outer wall of the outer cylinder 1. A second trachea is fixedly penetrated through the inner wall of the inner cylinder 11. A fixing mechanism 2 is arranged inside the inner cylinder 11. A plugging member 3 for plugging the through hole is arranged on the top surface of the fixing block 12. A sampling mechanism 4 is arranged inside the inner cylinder 11 and is detachably connected inside the fixing mechanism 2 for sampling the tumor of a patient. The sampling mechanism 4 includes a sleeve 41 detachably connected inside the fixing mechanism 2. The bottom end of the sleeve 41 is fixedly connected with a syringe needle 42 communicated with the inside of the sleeve 41. A piston 44 is slidably sleeved inside the sleeve 41. The bottom end of the piston 44 is fixedly connected with a core needle 45 slidably penetrating through the syringe needle 42. A rubber ring is fixedly connected to the inner wall of the sleeve 41. An extraction mechanism 5 is arranged above the fixing mechanism 2 for controlling the sampling mechanism 4 to pick up the tissue fluid and tissue mass in the tumor.

[0039] Specifically, first, the lowering of the fixing mechanism 2 causes the plugging member 3 to rotate and open the through-hole. Then, the sleeve 41 is installed inside the fixing mechanism 2. Then, the fixing mechanism 2 rises to its original position, driving the sleeve 41 to rise and move into the interior of the inner cylinder 11, and causing the plugging member 3 to block the through-hole. Then, the interior of the inner cylinder 11 is evacuated by an air pump. Before taking a tumor sample, first place the outer cylinder 1 on the patient's body with the puncture point within the range of the inner cylinder 11. Then, evacuate the space between the inner cylinder 11 and the outer cylinder 1 by the air pump so that the outer cylinder 1 can be adsorbed on the patient's body (this principle is similar to cupping). The fixing block 12 is in close contact with the patient's skin, so that the outer cylinder 1 can be fixed on the patient's body. Then, the downward movement of the fixing mechanism 2 can drive the sleeve 41 to move downward until the syringe needle 42 on the sleeve 41 pierces into the tumor. When it is necessary to obtain tissue blocks and tissue fluid in the tumor, the downward movement of the extraction mechanism 5 can be carried out so that the extraction mechanism 5 is connected to the piston 44. Since the initial position of the piston 44 is above the rubber ring, during the rapid downward pressing of the extraction mechanism 5, the piston 44 can drive the core needle 45 to move out of the syringe needle 42. Since there is a sampling port on the core needle 45, a part of the tissue block can be intercepted in the sampling port (this principle is the same as that of a biopsy needle for obtaining tissue blocks in the prior art). Then, driving the piston 44 to move upward by the extraction mechanism 5 can cause the intercepted tissue block to be received into the syringe needle 42 along with the core needle 45. As the extraction mechanism 5 drives the piston 44 to move upward, the tissue fluid in the tumor can be sucked into the sleeve 41 through the syringe needle 42, so that the simultaneous acquisition of tissue fluid and tissue blocks can be realized, so that the testing personnel can test the tissue blocks and tissue fluid. Then, through the combination of the two, the determination of the tumor nature can be increased. Then, the fixing mechanism 2 drives the sleeve 41 to move upward, causing the syringe needle 42 to be pulled out of the patient's body and received into the inner cylinder 11. When the syringe needle 42 is completely received into the inner cylinder 11, the plugging member 3 blocks the through-hole. Then, the outer cylinder 1 can be pulled off the patient's body. During the process of piercing the syringe needle 42 into the tumor, obtaining the sample, and pulling the syringe needle 42 out of the patient's body, the outer cylinder 1 is always adsorbed on the patient's body. Moreover, since the fixing block 12 is always in close contact with the patient's body, the puncture point is a flat surface. Therefore, during needle insertion, obtaining the tumor sample, and needle withdrawal, the inner cylinder 11 is always in a vacuum state, so that germs in the air can be prevented from entering the patient's body along with the syringe needle 42. Then, the medical staff can send the whole device to the laboratory for inspection. Since the plugging member 3 blocks the through-hole after the syringe needle 42 is received into the inner cylinder 11 and the outer cylinder 1 is still adsorbed on the patient's body, when the outer cylinder 1 is pulled off the patient's body, the inner cylinder 11 is still in a vacuum state. Therefore, during the process of sending the sample for inspection, the obtained sample is still in a vacuum environment, so that the sample can be prevented from being contaminated by the external environment during the journey of sending the sample for inspection. When it is necessary to take out the obtained sample from the inner cylinder 11, the fixing mechanism 2 can be used to drive the sleeve 41 to move downward.Until a part of the sleeve 41 extends out of the inner cylinder 11, then the sleeve 41 can be removed from the fixing mechanism 2 by rotating the sleeve 41. Then, the piston 44 is pulled out of the sleeve 41, and the obtained sample is taken out for testing. Finally, the inner cylinder 11 is sterilized. To facilitate observing the situation inside the inner cylinder 11, the outer cylinder 1 and the inner cylinder 11 are made of transparent materials.

[0040] Embodiment 1

[0041] As Figure 4 And Figure 6 As shown, in this embodiment, the fixing mechanism 2 includes a moving ring 21 that slides inside the inner cylinder 11. A threaded ring 22 is arranged inside the moving ring 21. A plurality of connecting rods 23 are fixedly connected to the threaded ring 22 and the moving ring 21 at equal angular intervals in a circular shape. A threaded groove 43 that is screwed and connected to the threaded ring 22 is opened at the top end of the outer wall of the sleeve 41. The diameter of the through hole is larger than the diameter of the sleeve 41. A limiting ring 49 is fixedly connected to the outer wall of the sleeve 41 and below the threaded groove 43.

[0042] In this embodiment, by opening a threaded groove 43 at the top end of the outer wall of the sleeve 41, the sleeve 41 can be fixed in the threaded ring 22, so that it is convenient for the sleeve 41 to move up and down following the moving ring 21. The limiting ring 49 can prevent the threaded groove 43 from separating from the threaded ring 22.

[0043] Embodiment 2

[0044] As Figure 4 And Figure 5 As shown, in this embodiment, a multi-stage telescopic member 24 is fixedly connected to the bottom surface of the moving ring 21. A cylindrical sleeve 25 is fixedly connected to the bottom end of the multi-stage telescopic member 24. Steel balls are fixedly connected to the inner wall of the cylindrical sleeve 25. The plugging member 3 includes a rotating shaft 31 rotatably connected to the fixed block 12. A blocking block 32 is fixedly connected to the outer wall of the rotating shaft 31. Two symmetrically arranged guide rails 33 are fixedly connected to the outer wall of the rotating shaft 31 up and down. A threaded sleeve 26 is rotatably penetrated through the top surface of the outer cylinder 1. A first screw 27 fixedly connected to the moving ring 21 is screwed and connected inside the threaded sleeve 26. A first screwing block is fixedly connected to the top end of the threaded sleeve 26. A fixing ring 13 is fixedly connected to the inner wall of the inner cylinder 11 and above the moving ring 21.

[0045] In this embodiment, by rotating the threaded sleeve 26, the first screw rod 27 can drive the moving ring 21 to move. The movement of the moving ring 21 can drive the cylindrical sleeve 25 to move through the multi-stage telescopic member 24 (the multi-stage telescopic member 24 is a prior art and will not be elaborated here). When the cylindrical sleeve 25 moves downward and sleeves on the rotating shaft 31, the steel balls in the cylindrical sleeve 25 slide into between the two guide rails 33. Since the two guide rails 33 are arc-shaped structures and extend downward, the downward movement of the cylindrical sleeve 25 can cause the rotating shaft 31 to rotate. The rotating rotating shaft 31 can drive the blocking block 32 to rotate, so that the through hole can be opened, facilitating medical staff to fix the sleeve 41 in the threaded ring 22, or insert the syringe 42 into the tumor. When the cylindrical sleeve 25 rises, the rotating shaft 31 can rotate in the reverse direction, causing the blocking block 32 to block the through hole, preventing air from entering the inner cylinder 11 when the outer cylinder 1 is pulled away.

[0046] Embodiment Three

[0047] As Figure 6 - Figure 9 As shown in the figure, in this embodiment, a fixed rod 46 is fixedly connected to the top end of the piston 44, a pressing block 47 is fixedly connected to the top end of the fixed rod 46, and a first magnet 48 is fixedly embedded in the top end of the pressing block 47. The extraction mechanism 5 includes a round rod 51 that penetrates and slides through the top surface of the outer cylinder 1. A cylindrical groove is opened at the bottom end of the round rod 51. A second screw rod 52 is screwed through the inner top surface of the cylindrical groove. The bottom end of the second screw rod 52 is rotatably connected to a connecting block 521. A second magnet 522 that attracts the first magnet 48 is fixedly connected to the bottom end of the connecting block 521. A plurality of limiting strips 511 are fixedly connected to the inner wall of the cylindrical groove at equal angles in a ring shape. A limiting block 512 is fixedly connected to the bottom end of the limiting strip 511. Embedding grooves are opened on the outer wall of the connecting block 521 corresponding to the limiting strips 511. Limiting grooves are opened on the top surface of the pressing block 47 corresponding to the limiting strips 511. Two symmetrical limiting plates 513 that penetrate and slide through the top surface of the outer cylinder 1 are fixedly connected to the outer wall of the round rod 51.

[0048] In this embodiment, by pressing down the round rod 51, the pressing block 47 enters the cylindrical groove, and the first magnet 48 attracts the second magnet 522. Continuing to press down the round rod 51 can drive the piston 44 to drive the core needle 45 to move downward, so that the tumor tissue mass can be obtained through the core needle 45. Since the first magnet 48 attracts the second magnet 522, the upward movement of the round rod 51 can drive the piston 44 and the core needle 45 to move upward, so that the obtained tissue mass can be collected into the syringe 42. As the round rod 51 continues to move upward, the tissue fluid in the tumor can be extracted. Since in some examinations, only one of the tissue fluid or the tissue mass is required (for superficial masses, usually the tissue fluid is extracted for examination, and for tumors in deeper parts, usually the tissue mass of the tumor is obtained), so when only the tissue fluid of the tumor needs to be obtained, by moving the round rod 51 downward, the first magnet 48 attracts the second magnet 522. Due to the existence of the rubber ring, the downward movement of the round rod 51 will be subject to greater resistance. Therefore, when the downward movement of the round rod 51 is subject to greater resistance, the piston 44 is driven to move upward by the reverse movement of the round rod 51, so that the tissue fluid in the tumor can be extracted into the sleeve 41. When only the tumor tissue mass needs to be obtained, by moving the round rod 51 downward, the first magnet 48 attracts the second magnet 522, and then the round rod 51 is moved downward again to drive the piston 44 to drive the core needle 45 to extend out from the inside of the syringe 42, and the tumor tissue mass is obtained. Then, the upward movement of the round rod 51 drives the piston 44 to move upward until the top end of the piston 44 contacts the rubber ring. At this time, the tumor tissue mass is collected into the syringe 42. Then, by rotating the second screw rod 52, the second magnet 522 can be separated from the first magnet 48, and then the sleeve 41 is driven to move upward and collected into the inner cylinder 11 by the fixing mechanism 2. This device can control the movement of the piston 44 through the round rod 51, and control the separation of the second magnet 522 from the first magnet 48 through the second screw rod 52, and can obtain the required tissue according to the actual situation, or obtain both tissues at the same time, thereby improving the universality of the use of this device.

[0049] Embodiment 4

[0050] As Figure 10 shown, in this embodiment, two fixing seats 14 for the vehicle are fixedly connected to the top surface of the outer cylinder 1. The top end of the round rod 51 is fixedly connected with a fixing plate 53. Two symmetrical notches 531 are formed in the outer wall of the fixing plate 53. Two symmetrical locking members 54 are arranged between the fixing plate 53 and the outer cylinder 1. The locking member 54 includes a positioning rod 541 clamped with the corresponding notch 531. Both ends of the positioning rod 541 are fixedly connected with positioning blocks 542. A slider 543 is slidably penetrated through the outer wall of the positioning rod 541. A spring 544 is fixedly connected between the slider 543 and the lower positioning block 542. The bottom end of the lower positioning block 542 is fixedly connected with a rotating block 545 rotatably connected to the corresponding fixing seat 14.

[0051] In this embodiment, by moving the two sliders 543 downward to compress the springs 544 at the corresponding positions, and then by rotating the two positioning rods 541, the positioning rods 541 are disengaged from the fixing plate 53, so that the restriction on the round rod 51 can be released, enabling the round rod 51 to slide within the outer cylinder 1. By erecting the positioning rods 541 and having the positioning rods 541 located within the notches 531 at the corresponding positions, and then tightly contacting the sliders 543 with the bottom surface of the fixing plate 53 through the springs 544, the round rod 51 can be supported to prevent the round rod 51 from colliding with the pressing block 47 under its own gravity, which may cause the piston 44 to drive the core needle 45 to move and contact the blocking block 32, breaking the core needle 45.

[0052] For those skilled in the art, it is obvious that the present invention is not limited to the details of the above-described exemplary embodiments, and without departing from the spirit or basic characteristics of the present invention, the present invention can be implemented in other specific forms. Therefore, from any perspective, the embodiments should be regarded as exemplary and non-limiting. The scope of the present invention is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be encompassed within the present invention. Any reference signs in the claims should not be regarded as limiting the claims involved.

[0053] In addition, it should be understood that although this specification is described in accordance with the embodiments, not every embodiment only contains an independent technical solution. This narrative manner of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in the various embodiments can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. An in-vivo sampling and submission device for oncology department, characterized in that, Comprising: An outer cylinder (1), an inner top surface of the outer cylinder (1) is fixedly connected with an inner cylinder (11), a bottom end of an inner wall of the inner cylinder (11) is fixedly connected with a fixing block (12), and a through hole is formed through a top surface of the fixing block (12); A fixing mechanism (2), arranged inside the inner cylinder (11); A plugging member (3), arranged on the top surface of the fixing block (12) for plugging the through hole; A sampling mechanism (4), arranged inside the inner cylinder (11) and detachably connected inside the fixing mechanism (2) for sampling inside a patient's tumor. The sampling mechanism (4) includes a sleeve (41) detachably connected inside the fixing mechanism (2), a bottom end of the sleeve (41) is fixedly connected with a syringe needle (42) communicating with the inside of the sleeve (41), a piston (44) is slidably sleeved inside the sleeve (41), a bottom end of the piston (44) is fixedly connected with a core needle (45) slidably penetrating through the syringe needle (42), and a rubber ring is fixedly connected to an inner wall of the sleeve (41); An extraction mechanism (5), arranged above the fixing mechanism (2) for controlling the sampling mechanism (4) to pick up tissue fluid and tissue blocks inside the tumor.

2. The oncology in-vivo sampling and submission device according to claim 1, characterized in that, The fixing mechanism (2) includes a moving ring (21) slidable inside the inner cylinder (11), a threaded ring (22) is arranged inside the moving ring (21), and a plurality of connecting rods (23) are fixedly connected between the threaded ring (22) and the moving ring (21) at equal angular intervals in a circumferential direction. A threaded groove (43) for screwing connection with the threaded ring (22) is formed at a top end of an outer wall of the sleeve (41).

3. The oncology in-vivo sampling and submission device according to claim 2, characterized in that, A diameter of the through hole is larger than a diameter of the sleeve (41), and a limiting ring (49) is fixedly connected to the outer wall of the sleeve (41) and below the threaded groove (43).

4. The oncology in-vivo sampling and submission device according to claim 3, characterized in that, A bottom surface of the moving ring (21) is fixedly connected with a multi-stage telescopic member (24), a bottom end of the multi-stage telescopic member (24) is fixedly connected with a cylindrical sleeve (25), steel balls are fixedly connected to an inner wall of the cylindrical sleeve (25), the plugging member (3) includes a rotating shaft (31) rotatably connected to the fixing block (12), a blocking block (32) is fixedly connected to an outer wall of the rotating shaft (31), and two guide rails (33) symmetrically arranged up and down are fixedly connected to the outer wall of the rotating shaft (31).

5. The in-vivo sampling and submission device for oncology according to claim 4, characterized in that, A threaded sleeve (26) is rotatably penetrated through a top surface of the outer cylinder (1), a first screw rod (27) fixedly connected with the moving ring (21) is screwed inside the threaded sleeve (26), and a first screwing block is fixedly connected to a top end of the threaded sleeve (26).

6. The oncology in-vivo sampling and submission device according to claim 5, characterized in that, A fixing ring (13) is fixedly connected to an inner wall of the inner cylinder (11) and above the moving ring (21).

7. The oncology in-vivo sampling and submission device according to claim 6, characterized in that, A top end of the piston (44) is fixedly connected with a fixing rod (46), a top end of the fixing rod (46) is fixedly connected with a pressing block (47), a first magnet (48) is fixedly embedded at a top end of the pressing block (47), and the extraction mechanism (5) includes a round rod (51) slidably penetrating through a top surface of the outer cylinder (1). A cylindrical groove is formed at a bottom end of the round rod (51), a second screw rod (52) is screwed through an inner top surface of the cylindrical groove, a bottom end of the second screw rod (52) is rotatably connected with a connecting block (521), and a second magnet (522) attracting the first magnet (48) is fixedly connected to a bottom end of the connecting block (521).

8. The oncology in-vivo sampling and submission device according to claim 7, wherein, A plurality of limiting strips (511) are fixedly connected to the inner wall of the cylindrical groove at equal angles in a ring shape. The bottom end of the limiting strip (511) is fixedly connected to a limiting block (512). Embedding grooves are formed in the outer wall of the connecting block (521) corresponding to the limiting strips (511). Limiting grooves are formed in the top surface of the pressing block (47) corresponding to the limiting strips (511).

9. The oncology in-vivo sampling and submission device according to claim 8, characterized in that, Two symmetrical limiting plates (513) that penetrate and slide on the top surface of the outer cylinder (1) are fixedly connected to the outer wall of the round rod (51).

10. The oncology in-vivo sampling and submission device according to claim 8, wherein, Two fixed seats (14) facing the interior of the vehicle are fixedly connected to the top surface of the outer cylinder (1). The top end of the round rod (51) is fixedly connected to a fixing plate (53). Two symmetrical notches (531) are formed in the outer wall of the fixing plate (53). Two symmetrical locking members (54) are arranged between the fixing plate (53) and the outer cylinder (1). The locking member (54) includes a positioning rod (541) that is clamped with the notch (531) at the corresponding position. Positioning blocks (542) are fixedly connected to both ends of the positioning rod (541). A slider (543) penetrates and slides on the outer wall of the positioning rod (541). A spring (544) is fixedly connected between the slider (543) and the lower positioning block (542). The bottom end of the lower positioning block (542) is fixedly connected to a rotating block (545) that is rotatably connected to the corresponding fixed seat (14).