Rhamnolipid composition as well as preparation method and application thereof

Abstract

The invention discloses a rhamnolipid composition as well as a preparation method and application thereof. The composition is prepared from the following components: rhamnolipid, an associative thickening agent, an acid-resistant hydrophilic thickening agent and a water-containing carrier. The composition has a tighter micelle structure, solves the problem that the rhamnolipid surfactant system cosmetics are difficult to thicken, relieves the yellowing phenomenon in the product storage process, improves the skin feeling, and has great application value.

Description

Technical Field

[0001] The present invention relates to the field of daily chemicals, and particularly relates to a rhamnolipid composition, a preparation method thereof and an application thereof. Background Art

[0002] Under the guidance of consumer demands and environmental protection requirements, the process of replacing surfactants has accelerated. In recent years, amino acid surfactants that have emerged are gradually replacing traditional sulfate surfactants due to their outstanding mildness. Rhamnolipids are fermented from vegetable oils and have the advantages of being mild and non-irritating, 100% rapidly degradable, and having high surface activity, and will become a new generation of surfactants after amino acid surfactants.

[0003] In cosmetics, viscosity is an important element in the consumer experience. Products with high viscosity are more conducive to dispensing and give the impression of a higher content. The viscosity requirements for traditional shampoos and body washes are above 3000 mPa·s, so thickening is a necessary step in the formulation. Formulators often determine the corresponding thickening scheme according to the type of main surfactant. Currently, commonly used sulfate surfactants are easy to form micelles, and the ideal viscosity can be achieved by simply adjusting the charge or adding a thickening agent. Since the hydrophilic group of amino acid surfactants is large, the micellization process is not smooth, and the conventional thickening scheme is difficult to meet the requirements. This problem once restricted the development of amino acid surfactants. However, the thickening of rhamnolipids is more difficult than that of amino acid surfactants. Its molecules are larger than amino acids, and the hydrophilic groups are dispersed, making it more difficult to form micelles. Moreover, when it is compounded with a conventional surfactant system, it is extremely easy to destroy the micelle structure of the original system, resulting in a decrease in the viscosity of the product. Since there is currently no effective thickening scheme for rhamnolipids, it is urgent to solve this problem. In addition, sugar lipids have the problem of easy yellowing, which changes the appearance of the product.

[0004] Therefore, it is necessary to develop a rhamnolipid composition that can meet the market requirements for viscosity and has a stable appearance. Summary of the Invention

[0005] In order to overcome the deficiencies in the prior art, on the one hand, the present invention provides a rhamnolipid composition, comprising the following components:

[0006] (a) 1-50 parts by weight of rhamnolipid, preferably 10-25 parts by weight.

[0007] (b) 0.5-20 parts by weight of an associative thickening agent, preferably 1-5 parts by weight.

[0008] (c) 0.5-20 parts by weight of an acid-resistant hydrophilic thickening agent, preferably 1-10 parts by weight.

[0009] (d) An aqueous carrier, the amount of which is such that the sum of the parts by weight of the components in the composition is 100 parts by weight.

[0010] The rhamnolipid structure described in the present invention is shown in the following formula (1):

[0011]

[0012] Wherein: m = 1 or 0, n = 1 or 0, R 1 and R 2 are independent of each other, the same or different, and are organic groups having 2-24 carbon atoms, optionally unsaturated or optionally substituted, including alkyl groups, alkenyl groups substituted or unsubstituted with hydroxyl or amino groups.

[0013] When n = 1, the rhamnolipid is a disaccharide lipid at this time, and the general formula of the sugar ring part structure is denoted as RHARHA; when n = 0, the rhamnolipid is a monosaccharide lipid at this time, and the general formula of the sugar ring part structure is denoted as RHA; for the rhamnolipid with m = 0, the lipid structure thereof only contains one R-based aliphatic chain, so it is correspondingly denoted as RHARHA-CA or RHA-CA; correspondingly, for the rhamnolipid with m = 1, the lipid structure thereof contains one R 1 and R 2 two aliphatic chains, so it is correspondingly denoted as RHARHA-CACB or RHA-CACB.

[0014] Preferably, m = 1 in the rhamnolipid described in the present invention; more preferably, the rhamnolipid described in the present invention contains 5wt%-49wt% of RHA-CACB and 51wt%-95wt% of RHARHA-CACB, preferably 25wt%-40wt% of RHA-CACB and 60wt%-75wt% of RHARHA-CACB, wherein A and B are independently selected from 2-24, preferably 8-12. Wherein A is the number of carbon atoms of R 1 carbon atoms, and B is the number of carbon atoms of R 2 carbon atoms.

[0015] The associative thickener described in the present invention can be used in acidic systems, including polyurethane associative thickeners and / or hydrophobically modified hydroxyethyl cellulose;

[0016] Preferably, the polyurethane associative thickener contains one or more monofunctional hydrophobic capping structures on the main chain, and the molecular weight is 2000-20000, such as TU35 of Wanhua Chemical; preferably, the hydrophobically modified hydroxyethyl cellulose has an alkyl or haloalkyl capping structure, and the molecular weight is in the range of 20000-700000. TU35; preferably, the hydrophobically modified hydroxyethyl cellulose has an alkyl or haloalkyl capping structure, and the molecular weight is in the range of 20000-700000.

[0017] The acid-resistant hydrophilic thickener described in the present invention includes one or more of the following thickeners: PEG-containing, fatty acid-based, fatty alcohol-based, alkanolamide, fatty alcohol polyoxyethylene ether-based;

[0018] Preferably, the PEG-containing compounds are selected from PEG-n (n = 3, 4, 8, 150) distearates, PEG-120 methyl glucose dioleate, PEG-160 sorbitan triisostearate, PEG-200 hydrogenated glyceryl palmitate, and more preferably PEG-150 distearate;

[0019] Preferably, the fatty acids are selected from one or more of lauric acid, palmitic acid, linoleic acid, linolenic acid, myristic acid, stearic acid, behenic acid, and more preferably stearic acid;

[0020] Preferably, the fatty alcohols are selected from one or more of lauryl alcohol, myristyl alcohol, decyl alcohol, hexyl alcohol, octyl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, and more preferably cetyl alcohol;

[0021] Preferably, the alkanolamides are selected from one or more of coconut amide, lauroyl-myristoyl diethanolamide, isostearyl diethanolamide, linoleyl diethanolamide, myristyl diethanolamide, palm monoethanolamide, stearamide, and more preferably coconut amide;

[0022] Preferably, the fatty alcohol polyoxyethylene ethers are selected from one or more of cetyl alcohol polyoxyethylene (3) ether, isocetyl alcohol polyoxyethylene (10) ether, lauryl alcohol polyoxyethylene (3) ether, lauryl alcohol polyoxyethylene (10) ether, and more preferably lauryl alcohol polyoxyethylene (10) ether.

[0023] The aqueous carrier of the present invention includes deionized water and optional additives, where the additives are one or more of oil esters, silicone oils, humectants, preservatives, emulsifiers, chelating agents, and fragrances. Further, the additives are from natural products.

[0024] The selection and dosage of the optional additives depend on the target use and can refer to the common general knowledge in the art.

[0025] Preferably, the pH of the rhamnolipid composition is 5 - 7, which can be optionally adjusted by a pH regulator; further, the pH regulator is selected from at least one of sodium hydroxide, potassium hydroxide, ammonium chloride, citric acid, sodium citrate, and acetic acid, and preferably sodium hydroxide and citric acid.

[0026] On the other hand, the present invention provides a preparation method of the above-mentioned rhamnolipid composition, and the specific preparation method is as follows:

[0027] (1) Add part of the water into a stirring pot, add rhamnolipid, acid-resistant hydrophilic thickener, and optional additives, and stir;

[0028] (2) Heat up to 55 - 65 °C, add an associative thickener, and stir;

[0029] (3) Add water and an optional pH regulator to adjust the pH of the composition to 5 - 7;

[0030] (4) Lower the temperature, stop stirring, and discharge the product.

[0031] The third aspect of the present invention provides the above-mentioned rhamnolipid composition as a washing and care formulation, which is applied to mass washing and care products with a required viscosity > 3000 mPa·s.

[0032] Compared with the prior art, the present invention has the following beneficial effects:

[0033] The present invention provides a rhamnolipid composition, controls the proportion of the monosaccharide lipid ring in the rhamnolipid, and simultaneously adds an acid-resistant hydrophilic thickener and an associative thickener, enabling the rhamnolipid to form macromolecules through the association of hydrophobic chains, and then synergistically form a three-dimensional network structure with the hydrophilic thickener. By controlling the pH of the composition under acidic conditions, the micellization process of the rhamnolipid is promoted. This composition can achieve self-thickening, and at the same time can also reduce the yellowing reaction in the product, making the product appearance stable. In addition, the product also has more excellent wetting properties and a more refreshing skin feel, and can be applied to mass washing and care products with a required viscosity > 3000 mPa·s. Detailed implementation mode

[0034] Source of raw materials:

[0035] Rhamnolipid: Wanhua Chemical Group Co., Ltd.; among them, R 1 and R 2 are unsubstituted straight-chain alkyl groups;

[0036] Polyurethane thickener: Wanhua Chemical Group Co., Ltd. TU35;

[0037] p-Hydroxyacetophenone (preservative, 99%): aladdin;

[0038] 1,2-Pentanediol (preservative): aladdin;

[0039] Hydrophobically modified hydroxyethyl cellulose: Ashland NatrosolPlus330, USA;

[0040] Testing method:

[0041] Viscosity: GB / T 2794 - 2013 (Brookfield LV, 62# / 20 rpm);

[0042] Refreshing degree: Conduct a test on the consumer use experience, and evaluate 60 consumers with an average age of 25 years. The evaluation method is to select the refreshing degree on a scale of 1 - 5, where 1 is very poor, 3 is average, and 5 is very good;

[0043] Fabric wetting: GB 11983 - 2008 (composition concentration 0.05 wt%), the shorter the wetting time, the better;

[0044] Heat storage stability: Store at 50 °C, test the color number on the 0th, 7th, 14th, and 28th days. The larger the color number, the darker the color;

[0045] Method for testing color number (Hazen): GB / T 3143 - 1982;

[0046] Skin contact angle: Measured with a Dataphysics OCA - 25 contact angle measuring instrument in Germany on the surface of pigskin to measure the dynamic contact angle. Take the result at 1 min. The smaller the contact angle, the better the wetting effect.

[0047] The components and dosages of the compositions in each example are shown in Table 1, and the preparation method is carried out in the following steps:

[0048] (1) Add part of the water to a stirring pot, add rhamnolipid, acid - resistant hydrophilic thickener, and optional additives, and stir until evenly mixed;

[0049] (2) Heat up to 60 °C, add an associative thickener, and stir;

[0050] (3) Add water to 100 parts by weight, and optionally adjust the pH;

[0051] (4) Cool down, stop stirring, and discharge the material.

[0052] Table 1 Dosages of the compositions in each example (parts by weight)

[0053]

[0054]

[0055] Table 2 Dosages of the compositions in each comparative example (parts by weight)

[0056]

[0057] Table 3 Performance test results of examples and comparative examples

[0058]

[0059]

[0060] The above results show that the composition provided by the present invention has a relatively large viscosity, a refreshing skin feel, excellent wetting performance, and a stable appearance. In Comparative Example 3, due to the too - low pH, rhamnolipid precipitated, and the appearance change could not be tested.

[0061] Unless otherwise specified, the terms used in this invention have the meanings commonly understood by those skilled in the art.

[0062] The embodiments described in this invention are for illustrative purposes only and are not intended to limit the scope of protection of this invention. Those skilled in the art can make various other substitutions, changes and improvements within the scope of this invention. Therefore, this invention is not limited to the above embodiments but is only defined by the claims.

Claims

1. A rhamnolipid composition, comprising the following components: (a) 1-50 parts by weight of mixed rhamnolipids, preferably 10-25 parts by weight; (b) 0.5-20 parts by weight of an associative thickener, preferably 1-5 parts by weight; (c) 0.5-20 parts by weight of an acid-resistant hydrophilic thickener, preferably 1-10 parts by weight; (d) An aqueous carrier, the amount used being such that the sum of the parts by weight of the components in the composition is 100 parts by weight.

2. The composition according to claim 1, characterized in that, The rhamnolipid contains 5wt%-49wt% of RHA-CACB and 51wt%-95wt% of RHARHA-CACB, preferably 25wt%-40wt% of RHA-CACB and 60wt%-75wt% of RHARHA-CACB; wherein A and B are independently selected from 2-24, preferably 8-12.

3. The composition according to claim 1, characterized in that, The associative thickener includes a polyurethane associative thickener and / or hydrophobically modified hydroxyethyl cellulose.

4. The composition according to claim 1, characterized in that, The acid-resistant hydrophilic thickener includes one or more of the following thickeners: PEG-containing, fatty acid, fatty alcohol, alkanolamide, fatty alcohol polyoxyethylene ether.

5. The composition according to claim 4, characterized in that, The PEG-containing is selected from PEG-n distearate, PEG-120 methyl glucoside dioleate, PEG-160 sorbitan triisostearate, PEG-200 hydrogenated glyceryl palmitate, where n = 3, 4, 8, 150; more preferably PEG-150 distearate; and / or: The fatty acids are selected from one or more of lauric acid, palmitic acid, linoleic acid, linolenic acid, myristic acid, stearic acid, behenic acid, more preferably stearic acid; and / or: The fatty alcohols are selected from one or more of lauryl alcohol, myristyl alcohol, decanol, hexanol, octanol, cetyl alcohol, stearyl alcohol, behenyl alcohol, more preferably cetyl alcohol; and / or: The alkanolamides are selected from one or more of coconut amide, lauroyl-myristoyl diethanolamide, isostearyl diethanolamide, linoleyl diethanolamide, myristyl diethanolamide, palmityl monoethanolamide, stearamide, more preferably coconut amide; and / or: The fatty alcohol polyoxyethylene ethers are selected from one or more of cetyl alcohol polyoxyethylene (3) ether, isocetyl alcohol polyoxyethylene (10) ether, lauryl alcohol polyoxyethylene (3) ether, lauryl alcohol polyoxyethylene (10) ether, more preferably lauryl alcohol polyoxyethylene (10) ether.

6. The composition according to claim 1, characterized in that, The aqueous carrier includes deionized water and optional additives, where the additives are one or more of oils and fats, silicone oils, humectants, preservatives, emulsifiers, chelating agents, fragrances.

7. The composition according to claim 1, characterized in that, The pH of the composition is 5-7, adjusted by an optional pH regulator.

8. The composition according to claim 7, characterized in that, The optional pH regulator is selected from at least one of sodium hydroxide, potassium hydroxide, ammonium chloride, citric acid, sodium citrate, and acetic acid.

9. The preparation method of the rhamnolipid composition according to any one of claims 1-8, characterized in that, The specific steps are as follows: (1) Add part of the water to a stirring pot, add rhamnolipids, acid-resistant hydrophilic thickener, and optional additives, and stir; (2) Heat up to 55-65°C, add the associative thickener, and stir; (3) Add water and optional pH regulator; (4) Cool down, stop stirring, and discharge the material.

10. Use of the rhamnolipid composition according to any one of claims 1-8 or the rhamnolipid composition prepared by the preparation method according to claim 9 in a washing and care product.

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