Medicine sterile intelligent proportioning and storing device with quality control module

Abstract

The invention relates to the technical field of medicine sterile intelligent proportioning and storage devices, in particular to a medicine sterile intelligent proportioning and storage device with a quality control module, which comprises a sterile bin, a booster pump is arranged at the upper part of an inner cavity of the sterile bin, and a lifting slide rail is arranged below the booster pump; a sliding block is installed in the lifting sliding rail in a left-right sliding mode, a screw rod is installed on the sliding block in a threaded mode, a first installation frame is fixedly welded to the front end face of the sliding block, a plurality of lifting air cylinders are fixed to the upper end face of the first installation frame through bolts, and a lifting driving rod is arranged below each lifting air cylinder. The invention has the following advantages: 1, a rapid fixing system for the injector, the penicillin bottle and the medicine storage bag is provided; 2, a multi-channel independent control suction system; 3, an automatic mixing and disposable sterile storage technology is adopted; and 4, the quality control module is used for checking and detecting / monitoring the liquid medicine.

Description

Technical Field

[0001] The present invention relates to the technical field of intelligent proportioning and storage devices for drug sterility, and particularly to an intelligent proportioning and storage device for drug sterility with a quality control module. Background Art

[0002] Currently, intelligent drug dispensers on the market are mainly developed to address the contamination risks caused by air contact and hand contact during the intravenous drug preparation process. Such devices are generally applicable to the preparation of powder injections and aqueous injections. Their basic principle is to automatically push and pull syringes to achieve the aspiration and injection of liquid medicine. The operation is simple and the injection and aspiration rates are adjustable, thus accelerating drug dissolution to a certain extent, saving human resources, and improving drug preparation efficiency. However, from the perspective of actual clinical applications, existing devices still have limitations in terms of automation, aseptic operation, and multi-drug mixing, and are difficult to fully meet the requirements of modern hospitals for high-precision, aseptic, and multi-channel drug proportioning. Specifically, the following problems exist:

[0003] 1. Manual intervention is still required during the operation process: The drug aspiration volume needs to be manually set. During the aspiration process, medical staff still need to hold the vial and manually insert the syringe into the vial, resulting in a cumbersome operation process and prone to operation errors.

[0004] 2. Single-channel aspiration limits multi-drug mixing: Existing devices can only aspirate one drug at a time. If multiple drugs need to be mixed, it is necessary to aspirate drug A, push it into the mixing bottle, replace the syringe, then aspirate drug B, and operate in this process in a cycle. The operation process is long and there are problems such as the mixing bottle being placed in an unsatisfactory position, being easily knocked over or contaminated.

[0005] 3. The drug dosage form does not match the dosage: The drug stock often exceeds the actual need, resulting in waste of medical resources and unreasonable use of medical insurance funds; there is a lack of a sterile storage device for accurately dispensing appropriate doses, and it is also difficult to prevent possible cross-infection between different patients using the same tube of drug.

[0006] 4. Insufficient aseptic and drug detection and verification: Existing devices lack the functions of integrated aseptic environment monitoring and liquid medicine parameter detection, and cannot compare the parameters of the stored solution (such as pH, absorbance, refractive index, etc.) with the standard product parameters in real time, posing risks of misloading and mislabeling, and may thus lead to medical accidents. Summary of the Invention

[0007] The purpose of the present invention is to provide an intelligent proportioning and storage device for drug sterility with a quality control module to solve the problems raised in the above background art.

[0008] To achieve the above object, the present invention provides the following technical solution. A drug aseptic intelligent proportioning and storage device with a quality control module includes a sterile chamber. A pressure pump is arranged in the upper part of the internal cavity of the sterile chamber. A lifting slide rail is arranged below the pressure pump. A slider is slidably installed left and right inside the lifting slide rail. A lead screw is threadedly installed on the slider. A first mounting bracket is fixedly welded to the front end face of the slider. A plurality of lifting cylinders are bolted to the upper end face of the first mounting bracket. A lifting drive rod is arranged below each lifting cylinder. A lifting plate is fixedly welded to the bottom end of each lifting drive rod. Side plates are fixedly welded to the left and right sides of the lower end face of the first mounting bracket. A suction cup is arranged below each lifting plate. An upper fixing plate is arranged below the suction cup. A lower fixing plate is arranged below the upper fixing plate. The upper fixing plate and the lower fixing plate are fixedly welded between the left and right side plates. A plurality of upper insertion holes are formed in the upper fixing plate. A plurality of lower insertion holes are formed in the lower fixing plate. The upper insertion holes and the lower insertion holes correspond to the positions of the suction cups one by one. A syringe barrel is detachably installed in a corresponding group of the upper insertion hole and the lower insertion hole. A syringe piston is arranged inside the syringe barrel.

[0009] As a preference of the above technical solution, a vial placement rack is arranged below the syringe barrel. A plurality of vial placement holes are formed in the vial placement rack. The vial placement holes correspond to the positions of the syringe barrels one by one. A second mounting bracket is arranged below the vial placement rack. A first card slot is formed in the right end of the second mounting bracket. A first fixing pin hole is formed in the first card slot. A first fixing pin hole is also formed in the vial placement rack. A first pin is detachably inserted into the first fixing pin hole.

[0010] As a preference of the above technical solution, a second card slot is formed in the left end of the second mounting bracket. A drug storage bag placement opening is formed in the second card slot. A drug guiding chamber is arranged in the drug storage bag placement opening. A sealing film is arranged in the upper part of the drug guiding chamber. The drug guiding chamber is sealed by the sealing film. A second fixing pin hole is formed in the sealing film. Limiting plates are arranged at the left and right ends of the sealing film. A second fixing pin hole is formed in the limiting plate. A second fixing pin hole is also formed in the second card slot. A second pin is detachably inserted into the second fixing pin hole. A collecting pipe is connected to the bottom of the drug guiding chamber. A drug storage bag is connected to the bottom of the collecting pipe. A drug storage bag placement rack is arranged below the drug storage bag. The top end of the drug storage bag placement rack is fixedly welded to the lower end face of the second mounting bracket.

[0011] Preferably, as the above technical solution, an L-shaped connecting plate is welded to the middle of the rear side wall of the second mounting bracket. A driving belt is arranged at the top of the L-shaped connecting plate. The L-shaped connecting plate and the driving belt are fixed by bolts. A driving wheel is arranged on each of the left and right sides of the driving belt. The driving belt is clamped in the left and right driving wheels. A driving box is arranged at the rear of the driving wheel. The right driving wheel is rotatably installed on the rear inner wall of the driving box. A driving motor is arranged at the rear of the left driving wheel. The driving motor is bolted to the rear outer wall of the driving box. The driving wheel is in transmission connection with the driving motor. A second opening is formed in the left side wall of the sterile chamber, and a first opening is formed in the right side wall of the sterile chamber.

[0012] Preferably, as the above technical solution, a sampling tube is further arranged on the upper part of the medicine storage bag. The sampling tube is communicated with the medicine storage bag. A peristaltic pump is arranged on the left side of the sampling tube. A quality control module is arranged on the left side of the peristaltic pump. The middle part of the sampling tube is detachably installed in the peristaltic pump. The left end of the sampling tube is detachably installed in the quality control module. The sampling tube is communicated with the quality control module.

[0013] Preferably, as the above technical solution, a sterilization module is bolted to the upper inner wall of the sterile chamber for performing sterilization operation on the inside of the sterile chamber.

[0014] Preferably, the sterilization module is an ultraviolet lamp.

[0015] The present invention provides a drug aseptic intelligent proportioning and storage device with a quality control module, which has the following beneficial effects:

[0016] 1. A rapid fixing system for syringes, vials and medicine storage bags

[0017] By using the clamping method of pins and pin holes, rapid positioning and clamping of vials and medicine storage bags are realized. The upper jack and the lower jack are used for rapid insertion of syringes. The clamping assembly can be integrally replaced to cooperate with syringes, vials and medicine storage bags of different sizes and specifications.

[0018] 2. A multi-channel independent control suction system

[0019] Multiple syringe barrels adopt independent control and synchronous operation technology, enabling the device to aspirate multiple drugs simultaneously; by inserting the syringe barrels into the upper jacks and lower jacks, rapid installation of the syringe barrels is achieved. Then, the lifting drive rod is driven to descend by a slider until the suction cup fits with the syringe piston. At this time, the suction cup is activated to adsorb and fix the syringe piston. Then, the lifting cylinder is used to drive the lifting drive rod to drive the syringe piston to rise, completing the aspiration operation of the liquid medicine; during the aspiration process, it is located in a positive-pressure sterile chamber to avoid contamination during the drug preparation process; in addition, real-time monitoring (such as pressure and flow sensors) and feedback systems can also be built into the suction cup, the lifting drive rod, and the lifting slide rail to ensure accurate aspiration dosage for each channel.

[0020] 3. Automatic mixing and disposable sterile storage technology

[0021] All components are medical devices and disposable consumables. The entire automatic mixing process is in a positive-pressure environment of the sterile chamber. At the same time, thorough sterilization and disinfection will be carried out before and after replacing the disposable consumables, effectively ensuring the sterile state of the entire drug preparation link.

[0022] 4. The quality control module is used for checking, inspecting / monitoring the liquid medicine

[0023] After the drug preparation is completed, the prepared drug in the drug storage bag can also be sampled and detected through a sampling tube. The quality control module can be a bacteria collection incubator or a component analyzer and other devices, used for analyzing the sterility of the prepared drug in the drug storage bag or detecting and analyzing the liquid medicine parameters (detection indicators include pH, absorbance, refractive index, etc.), automatically comparing with the standard product parameters. When the detected data deviates from the preset standard, the system will automatically alarm and record; at the same time, the quality control module is set as a detachable component, taking into account both individual use and combined use. Description of the drawings

[0024] Figure 1 It is a schematic structural diagram of the present invention in the drug preparation mode;

[0025] Figure 2 is Figure 1 the front view of;

[0026] Figure 3 It is a schematic structural diagram of the present invention in the syringe replacement mode;

[0027] Figure 4 It is a schematic structural diagram of the present invention in the drug storage bag replacement mode;

[0028] Figure 5 It is a connection relationship diagram of the second mounting bracket and the driving wheel in the present invention;

[0029] Figure 6Schematic diagram of the structure of the first mounting bracket in the present invention;

[0030] Figure 7 Connection relationship diagram of the drug storage bag, vial fixing bracket and second mounting bracket in the present invention.

[0031] In the figure: 1, sterile chamber; 2, booster pump; 3, lifting slide rail; 4, lead screw; 5, slider; 6, first mounting bracket; 7, lifting cylinder; 8, lifting drive rod; 9, lifting plate; 10, side plate; 11, suction cup; 12, syringe piston; 13, upper fixing plate; 14, lower fixing plate; 15, upper jack; 16, lower jack; 17, syringe barrel; 18, vial placement rack; 19, vial placement hole; 20, first fixing pin hole; 21, second mounting bracket; 22, first card slot; 23, first pin; 24, second card slot; 25, second fixing pin hole; 26, drug storage bag placement opening; 27, drug storage bag placement rack; 28, limiting plate; 29, sealing film; 30, medicine guiding chamber; 31, medicine collecting pipe; 32, drug storage bag; 33, second pin; 34, L-shaped connecting plate; 35, drive belt; 36, drive wheel; 37, drive box; 38, drive motor; 39, sampling pipe; 40, peristaltic pump; 41, quality control module; 42, sterilization module; 43, first opening; 44, second opening. Detailed implementation manners

[0032] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention.

[0033] As Figure 1 、 Figure 2 And Figure 6As shown in the figure, in this embodiment, a drug aseptic intelligent proportioning and storage device with a quality control module includes a sterile chamber 1. A booster pump 2 is arranged in the upper part of the inner cavity of the sterile chamber 1. A lifting slide rail 3 is arranged below the booster pump 2. A slider 5 is slidably installed left and right inside the lifting slide rail 3. A lead screw 4 is threadedly installed on the slider 5. A first mounting bracket 6 is fixedly welded to the front end face of the slider 5. A plurality of lifting cylinders 7 are bolted to the upper end face of the first mounting bracket 6. A lifting drive rod 8 is arranged below each lifting cylinder 7. A lifting plate 9 is fixedly welded to the bottom end of each lifting drive rod 8. Side plates 10 are fixedly welded to the left and right sides of the lower end face of the first mounting bracket 6. A suction cup 11 is arranged below each lifting plate 9. An upper fixing plate 13 is arranged below the suction cup 11. A lower fixing plate 14 is arranged below the upper fixing plate 13. The upper fixing plate 13 and the lower fixing plate 14 are fixedly welded between the left and right side plates 10. A plurality of upper insertion holes 15 are formed in the upper fixing plate 13. A plurality of lower insertion holes 16 are formed in the lower fixing plate 14. The upper insertion holes 15 and the lower insertion holes 16 correspond to the positions of the suction cups 11 one by one. A syringe barrel 17 is detachably installed in a corresponding group of upper insertion holes 15 and lower insertion holes 16. A syringe piston 12 is arranged inside the syringe barrel 17.

[0034] In specific implementation, during the proportioning process of the drug, the syringe barrel 17 is used to aspirate the liquid medicine in the vial below. Since multiple syringe barrels 17 adopt independent control and synchronous operation technologies, the device can aspirate multiple drugs simultaneously. By inserting the syringe barrel 17 into the upper insertion holes 15 and the lower insertion holes 16, the quick installation of the syringe barrel 17 is realized. Then, the slider 5 is used to drive the lifting drive rod 8 to descend until the suction cup 11 fits with the syringe piston 12. At this time, the suction cup 11 is started to make the suction cup 11 adsorb and fix with the syringe piston 12. Then, the lifting cylinder 7 is used to drive the lifting drive rod 8 to drive the syringe piston 12 to lift, completing the aspiration operation of the liquid medicine.

[0035] It should be noted that the lifting drive assembly of the lifting slide rail 3 is located outside the sterile chamber 1. When the syringe piston 12 sucks the liquid medicine, the lead screw 4 is used to drive the slider 5 to drive the syringe barrel 17 to align with the vial below. Then, the lifting drive assembly of the lifting slide rail 3 is used to drive the entire lifting slide rail 3 and the syringe barrel 17 installed on the lifting slide rail 3 to descend until the needle of the syringe barrel 17 is inserted into the vial below, and then the operation of sucking the liquid medicine can be carried out. At the same time, during the process of inserting the needle of the syringe barrel 17 into the rubber stopper of the vial, the slider 5 also needs to move slightly up and down to imitate the hand needle insertion action, which makes it more labor-saving when the needle of the syringe barrel 17 is inserted into the vial and avoids the breakage of the needle. During this process, the movement trajectories such as the alignment and positioning of the syringe barrel 17, the up and down movement distance of the slider 5, and the imitation of the hand needle insertion action of the slider 5 are all completed by the lower computer driving each component after programming the software on the upper computer, which is common knowledge in this field, so no more description will be given.

[0036] In addition, real-time monitoring (such as pressure and flow sensors) and feedback systems can also be built into the suction cup 11, the lifting drive rod 8, and the lifting slide rail 3 to ensure that the suction dosage of each channel is accurate and error-free.

[0037] As a further implementation of the present invention, please refer to Figure 2 and Figure 7 , a vial placement rack 18 is provided below the syringe barrel 17. A number of vial placement holes 19 are provided on the vial placement rack 18. The positions of the vial placement holes 19 correspond to those of the syringe barrel 17 one by one. A second mounting rack 21 is provided below the vial placement rack 18. A first card slot 22 is provided at the right end of the second mounting rack 21. A first fixing pin hole 20 is provided on the first card slot 22. A first fixing pin hole 20 is also provided on the vial placement rack 18. A first pin 23 is detachably inserted into the first fixing pin hole 20.

[0038] In specific implementation, the vial placement rack 18 is clamped in the first card slot 22, and then the first pin 23 is inserted into the first fixing pin holes 20 of the vial placement rack 18 and the first card slot 22 to realize the quick installation of the vial placement rack 18. Then, the vial is placed in the vial placement hole 19, and the positioning and installation of the vial are completed.

[0039] It should be noted that the vial placement rack 18 is a replaceable component. The aperture size of the vial placement holes 19 on the vial placement rack 18 is consistent with the vials placed therein, so as to realize the quick positioning and installation of vials of different sizes and shapes.

[0040] As a further implementation of the present invention, please refer to Figure 2 and Figure 7, a second card slot 24 is provided at the left end of the second mounting bracket 21. A medicine storage bag placement opening 26 is further provided in the second card slot 24. A medicine guiding bin 30 is arranged in the medicine storage bag placement opening 26. A sealing film 29 is arranged above the medicine guiding bin 30. The sealing film 29 seals the medicine guiding bin 30. A second fixing pin hole 25 is provided in the sealing film 29. Limiting plates 28 are arranged at the left and right ends of the sealing film 29. Second fixing pin holes 25 are provided in the limiting plates 28. Second fixing pin holes 25 are also provided in the second card slot 24. A second pin 33 is detachably inserted into the second fixing pin hole 25; a medicine collecting pipe 31 communicates with the bottom of the medicine guiding bin 30. The bottom of the medicine collecting pipe 31 communicates with a medicine storage bag 32. A medicine storage bag placement rack 27 is arranged below the medicine storage bag 32. The top end of the medicine storage bag placement rack 27 is welded and fixed to the lower end surface of the second mounting bracket 21.

[0041] In specific implementation, by limiting and clamping the limiting plate 28 in the second card slot 24, at this time, the sealing film 29 is clamped between the second card slot 24 and the limiting plate 28. Then, through the insertion and fixation of the second pin 33, the fixed installation of the sealing film 29 and the medicine guiding bin 30 below it is realized; after the syringe barrel 17 completes the operation of sucking medicine, the screw rod 4 drives the slider 5 to move directly above the sealing film 29. Then, the needle of the syringe barrel 17 is inserted downward into the sealing film 29 through the lifting slide rail 3. Then, the lifting cylinder 7 drives the suction cup 11 and the syringe piston 12 to move downward, and the liquid medicine in the syringe barrel 17 is injected into the medicine guiding bin 30. Finally, the liquid medicine flows into the medicine storage bag 32 through the medicine collecting pipe 31, completing the medicine preparation operation. During the medicine preparation process, the medicine storage bag 32 is supported by the medicine storage bag placement rack 27, avoiding the loosening of the medicine collecting pipe 31 from the medicine guiding bin 30 and the medicine storage bag 32 due to the excessive weight of the liquid medicine in the medicine storage bag 32.

[0042] It should be noted that the sealing film 29 is made of medical silicone material, the medicine guiding bin 30, the medicine collecting pipe 31 and the medicine storage bag 32 are made of medical PVC material. The sealing film 29, the medicine guiding bin 30, the medicine collecting pipe 31 and the medicine storage bag 32 are disposable consumables, all of which are existing medical devices, and the connection method is also the common connection method of infusion tubes and infusion bags, so no more description will be made.

[0043] As a further implementation scheme of the present invention, please refer to Figure 3 and Figure 5, a L-shaped connecting plate 34 is welded to the middle of the rear side wall of the second mounting bracket 21. A driving belt 35 is arranged at the top of the L-shaped connecting plate 34. The L-shaped connecting plate 34 and the driving belt 35 are fixed by bolts. A driving wheel 36 is arranged on each of the left and right sides of the driving belt 35. The driving belt 35 is clamped inside the left and right driving wheels 36. A driving box 37 is arranged at the rear of the driving wheel 36. The right driving wheel 36 is rotatably installed on the rear inner wall of the driving box 37. A driving motor 38 is arranged at the rear of the left driving wheel 36. The driving motor 38 is bolted to the rear outer wall of the driving box 37. The driving wheel 36 is in transmission connection with the driving motor 38.

[0044] In specific implementation, the driving motor 38 drives the driving wheel 36 to drive the driving belt 35 to move, so as to drive the L-shaped connecting plate 34 to move left and right, realizing the left and right movement of the second mounting bracket 21.

[0045] Please continue to refer to Figure 4 , a second opening 44 is formed on the left side wall of the sterile chamber 1, and a first opening 43 is formed on the right side wall of the sterile chamber 1.

[0046] In specific implementation, when the driving motor 38 drives the L-shaped connecting plate 34 to be in the middle position, at this time, the vial placement rack 18 and the sealing film 29 are in the working position. First, the syringe barrel 17 moves to directly above the vial placement rack 18. After the syringe barrel 17 aspirates the liquid medicine from the vial on the vial placement rack 18, the syringe barrel 17 then moves to directly above the sealing film 29, and injects the aspirated liquid medicine in the syringe barrel 17 into the sealing film 29. Finally, the liquid medicine in the sealing film 29 is collected into the medicine storage bag 32 to complete the medicine preparation operation.

[0047] When the driving motor 38 drives the L-shaped connecting plate 34 to be in the leftmost position, at this time, the sealing film 29 passes through the second opening 44 to the outside of the sterile chamber 1. At this time, the operator can quickly load and unload the medicine storage bag 32 to realize the collection of the prepared medicine and the replacement operation of the medicine storage bag 32.

[0048] When the driving motor 38 drives the L-shaped connecting plate 34 to be in the rightmost position, at this time, the vial placement rack 18 passes through the first opening 43 to the outside of the sterile chamber 1. At this time, the operator can replace the vial on the vial placement rack 18 that has been aspirated, and can also replace the vial placement rack 18 with different vial placement hole 19 sizes according to different medicine ratios, and realize the quick disassembly and assembly of the vial placement rack 18 through the first fixing pin hole 20 and the first pin 23.

[0049] It should be noted that when the sealing film 29 and the vial rack 18 are outside the sterile chamber 1, before being transferred into the inner cavity of the sterile chamber 1, the operator needs to perform sufficient sterilization operations on the sealing film 29 and the vial rack 18, which is common knowledge in this field, so no further description will be given.

[0050] As a further implementation plan of the present invention, please refer to Figure 2 and Figure 7 , a sampling tube 39 is also provided at the upper part of the drug storage bag 32. The sampling tube 39 communicates with the drug storage bag 32. A peristaltic pump 40 is provided on the left side of the sampling tube 39, and a quality control module 41 is provided on the left side of the peristaltic pump 40. The middle part of the sampling tube 39 is detachably installed in the peristaltic pump 40, and the left end of the sampling tube 39 is detachably installed in the quality control module 41. The sampling tube 39 communicates with the quality control module 41.

[0051] In specific implementation, the sampling tube 39 can sample and detect the prepared drugs in the drug storage bag 32. The quality control module 41 can be a bacteria collecting incubator or a component analyzer and other devices, which are used to analyze the sterility of the prepared drugs in the drug storage bag 32 or detect and analyze the liquid medicine parameters (detection indicators include pH, absorbance, refractive index, etc.), automatically compare with the standard product parameters, and when the detected data deviates from the preset standard, the system automatically alarms and records; at the same time, the quality control module 41 is set as a detachable component, taking into account both single use and combined use.

[0052] As a further implementation plan of the present invention, please refer to Figure 2 , a sterilization module 42 is bolted to the upper inner wall of the sterile chamber 1 for performing sterilization operations on the inside of the sterile chamber 1.

[0053] Furthermore, the sterilization module 42 is an ultraviolet lamp.

[0054] The present invention provides a drug aseptic intelligent proportioning and storage device with a quality control module, and the specific working principle is as follows:

[0055] First, use the sterilization module 42 to perform overall sterilization on the inside of the sterile chamber 1. After the disinfection is completed, start the booster pump 2 to make the inside of the sterile chamber 1 in a positive pressure state, which can effectively prevent external germs from entering the sterile chamber 1 and causing the drugs to be contaminated during the medicine preparation process.

[0056] Before dispensing medicine, the slider 5 drives the first mounting bracket 6 to move rightward through the first opening 43 to the outside of the sterile chamber 1. By inserting the syringe barrel 17 into the upper jack 15 and the lower jack 16, the rapid installation of the syringe barrel 17 is achieved. At the same time, the driving motor 38 drives the L-shaped connecting plate 34 to the rightmost position. At this time, the vial placement rack 18 moves rightward through the first opening 43 to the outside of the sterile chamber 1. At this time, the operator can replace the vials that have been aspirated on the vial placement rack 18, and can also replace the vial placement rack 18 with different vial placement holes 19 according to different drug ratios, and the rapid disassembly and assembly of the vial placement rack 18 are realized through the first fixing pin hole 20 and the first pin 23.

[0057] After the first mounting bracket 6 and the vial placement rack 18 are fully disinfected, the slider 5 drives the first mounting bracket 6 to re-enter the inner cavity of the sterile chamber 1 to the medicine aspiration station. At the same time, the vial placement rack 18 also enters the inner cavity of the sterile chamber 1 under the drive of the driving motor 38 and is at the medicine aspiration station. The slider 5 drives the lifting drive rod 8 to descend until the suction cup 11 fits with the syringe piston 12. At this time, the suction cup 11 is started to adsorb and fix the syringe piston 12. Then, the lifting drive assembly of the lifting slide rail 3 drives the lifting slide rail 3 and the syringe barrel 17 mounted on the lifting slide rail 3 to descend as a whole until the needle of the syringe barrel 17 is inserted into the vial below. At the same time, during the process of the needle of the syringe barrel 17 inserting into the rubber stopper of the vial, the slider 5 also needs to move slightly up and down to imitate the hand needle insertion action, ensuring that the needle of the syringe barrel 17 is more labor-saving when inserted into the vial and avoiding the breakage of the needle. Finally, the lifting cylinder 7 drives the lifting drive rod 8 to drive the syringe piston 12 to lift, completing the medicine aspiration operation.

[0058] After the aspiration is completed, the slider 5 drives the syringe barrel 17 back to directly above the sealing film 29, and then the needle of the syringe barrel 17 is inserted downward into the sealing film 29 through the lifting slide rail 3. Then, the lifting cylinder 7 drives the suction cup 11 and the syringe piston 12 to move downward to inject the medicine in the syringe barrel 17 into the medicine guiding chamber 30. Finally, the medicine flows into the medicine storage bag 32 through the medicine collecting pipe 31, completing the dispensing operation. During the dispensing process, the medicine storage bag 32 is supported by the medicine storage bag placement rack 27 to prevent the loosening of the medicine collecting pipe 31 from the medicine guiding chamber 30 and the medicine storage bag 32 due to the excessive weight of the medicine in the medicine storage bag 32.

[0059] After the dispensing is completed, the slider 5 drives the syringe barrel 17 to separate from the sealing film 29. Then, the L-shaped connecting plate 34 drives the sealing film 29 to move leftward through the second opening 44 to the outside of the sterile chamber 1. At this time, the operator can quickly load and unload the medicine storage bag 32 to realize the collection of the prepared medicine and the replacement operation of the medicine storage bag 32.

[0060] After the dispensing is completed, the prepared medicine in the medicine storage bag 32 can also be sampled through the sampling tube 39. The quality control module 41 can be a bacteria collecting incubator or a component analyzer, etc., and is used to analyze the sterility or detect and analyze the liquid medicine parameters (the detection indexes include pH, absorbance, refractive index, etc.) of the prepared medicine in the medicine storage bag 32, and automatically compare with the standard product parameters. When the detected data deviates from the preset standard, the system automatically alarms and records; at the same time, the quality control module 41 is set as a detachable component to take into account both individual use and combined use.

[0061] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A drug aseptic intelligent proportioning and storage device with a quality control module, including a sterile bin (1), characterized in that: A pressure pump (2) is arranged at the upper part of the internal cavity of the sterile chamber (1). A lifting slide rail (3) is arranged below the pressure pump (2). A slider (5) is slidably installed left and right inside the lifting slide rail (3). A lead screw (4) is installed on the slider (5) by threading. A first mounting bracket (6) is fixedly welded to the front end face of the slider (5). A plurality of lifting cylinders (7) are fixedly bolted to the upper end face of the first mounting bracket (6). A lifting drive rod (8) is arranged below each lifting cylinder (7). A lifting plate (9) is fixedly welded to the bottom end of each lifting drive rod (8). Side plates (10) are fixedly welded to the left and right sides of the lower end face of the first mounting bracket (6). A suction cup (11) is arranged below each lifting plate (9).

2. The aseptic intelligent proportioning and storage device for drugs with a quality control module according to claim 1, characterized in that: An upper fixing plate (13) is arranged below the suction cup (11). A lower fixing plate (14) is arranged below the upper fixing plate (13). The upper fixing plate (13) and the lower fixing plate (14) are fixedly welded between the left and right side plates (10). A plurality of upper jacks (15) are formed in the upper fixing plate (13). A plurality of lower jacks (16) are formed in the lower fixing plate (14). The upper jacks (15) and the lower jacks (16) correspond to the position of the suction cup (11) one by one. A syringe barrel (17) is detachably installed in a corresponding set of the upper jack (15) and the lower jack (16). A syringe piston (12) is arranged inside the syringe barrel (17).

3. The drug aseptic intelligent proportioning and storage device with a quality control module according to claim 2, characterized in that: A vial placement rack (18) is arranged below the syringe barrel (17). A plurality of vial placement holes (19) are formed in the vial placement rack (18). The vial placement holes (19) correspond to the position of the syringe barrel (17) one by one. A second mounting bracket (21) is arranged below the vial placement rack (18). A first card slot (22) is formed at the right end of the second mounting bracket (21). A first fixing pin hole (20) is formed in the first card slot (22). A first fixing pin hole (20) is also formed in the vial placement rack (18). A first pin (23) is detachably inserted into the first fixing pin hole (20).

4. The drug aseptic intelligent proportioning and storage device with a quality control module according to claim 3, characterized in that: A second card slot (24) is provided at the left end of the second mounting bracket (21). A drug storage bag placement opening (26) is further provided in the second card slot (24). A drug guiding bin (30) is arranged in the drug storage bag placement opening (26). A sealing film (29) is arranged above the drug guiding bin (30). The sealing film (29) seals the drug guiding bin (30). A second fixing pin hole (25) is provided in the sealing film (29). Limiting plates (28) are arranged at the left and right ends of the sealing film (29). Second fixing pin holes (25) are provided in the limiting plates (28). Second fixing pin holes (25) are also provided in the second card slot (24). A second pin (33) is detachably inserted into the second fixing pin hole (25). A medicine collecting pipe (31) communicates with the bottom of the drug guiding bin (30). A drug storage bag (32) communicates with the bottom of the medicine collecting pipe (31). A drug storage bag placement rack (27) is arranged below the drug storage bag (32). The top end of the drug storage bag placement rack (27) is welded and fixed to the lower end surface of the second mounting bracket (21).

5. The drug aseptic intelligent proportioning and storage device with a quality control module according to claim 4, characterized in that: An L-shaped connecting plate (34) is welded and arranged in the middle of the rear side wall of the second mounting bracket (21). A driving belt (35) is arranged at the top end of the L-shaped connecting plate (34). The L-shaped connecting plate (34) and the driving belt (35) are fixed by bolts. A driving wheel (36) is arranged on each of the left and right sides of the driving belt (35). The driving belt (35) is clamped in the left and right driving wheels (36). A driving box (37) is arranged behind the driving wheel (36). The right driving wheel (36) is rotatably installed on the rear inner wall of the driving box (37). A driving motor (38) is arranged behind the left driving wheel (36). The driving motor (38) is bolted to the rear outer wall of the driving box (37). The driving wheel (36) is in transmission connection with the driving motor (38). A second opening (44) is provided in the left side wall of the sterile chamber (1). A first opening (43) is provided in the right side wall of the sterile chamber (1).

6. The aseptic intelligent proportioning and storage device for drugs with a quality control module according to claim 5, characterized in that: A sampling pipe (39) is further arranged above the drug storage bag (32). The sampling pipe (39) communicates with the drug storage bag (32). A peristaltic pump (40) is arranged on the left side of the sampling pipe (39). A quality control module (41) is arranged on the left side of the peristaltic pump (40). The middle of the sampling pipe (39) is detachably installed in the peristaltic pump (40). The left end of the sampling pipe (39) is detachably installed in the quality control module (41). The sampling pipe (39) communicates with the quality control module (41).

7. The aseptic intelligent proportioning and storage device for drugs with a quality control module according to claim 6, characterized in that: A sterilization module (42) is bolted to the upper inner wall of the sterile chamber (1).

8. The aseptic intelligent proportioning and storage device for drugs with a quality control module according to claim 7, characterized in that: The sterilization module (42) is an ultraviolet lamp.

Images