Isolation perfusion system and control method

Abstract

The invention discloses an isolation perfusion system which comprises a rack, a main pipeline is arranged on the rack, and the main pipeline is connected with a liquid storage tank through a hose and a pump body; a pressure measuring flange is arranged on the main pipeline, a pore plate is arranged in the pressure measuring flange, two sides of the pressure measuring flange are connected with a liquid separating cylinder through pressure measuring guide pipes, the liquid separating cylinder is connected with a multi-valve group through a guide pipe, and the multi-valve group is connected with a pressure transmitter; a blow-off pipe is arranged on the liquid separating cylinder, a pressure guiding pipe is arranged on the multi-valve set and connected with the medium box through a pump body, and control valves are arranged on the pressure measuring guide pipe, the blow-off pipe and the pressure guiding pipe. According to the system, modular integration of industrial instrument isolated filling is achieved, fluid pressure changes can be accurately measured, the medium flow direction can be flexibly controlled, impurities or bubbles can be rapidly removed, traditional complex pipelines are simplified, operation efficiency and maintenance convenience are improved, and the system is particularly suitable for teaching training.

Description

Technical Field

[0001] The present invention relates to the field of industrial instruments, and particularly to an isolation perfusion system. Background Art

[0002] In industrial fields such as petrochemical and pharmaceutical industries, the instrument isolation perfusion system is a key device for protecting measuring instruments. At present, the mainstream instrument isolation perfusion systems mainly adopt two technical solutions: one is the manual pressure pump filling method, where the operator needs to repeatedly operate the piston pump manually to inject the isolation liquid (such as ethylene glycol solution) into the system. This method has a high labor intensity and low work efficiency, and it often takes 15 - 30 minutes to complete single-point filling; the other is the metering pump automatic filling method. Although it solves the problem of manual operation, it has extremely high requirements for equipment. Special metering pumps with large power, large volume, and high precision must be used, resulting in high equipment purchase and maintenance costs.

[0003] Existing instrument isolation perfusion systems generally have problems of complex structure and cumbersome operation. General operators need to undergo special training to master the usage method. Especially in teaching and training scenarios, the complexity of industrial equipment makes it difficult for trainees to intuitively understand the working principle of the system, and they are even less able to conduct fault simulation and practical operation training. However, there is currently no isolation perfusion system specifically designed for teaching and training on the market, which severely restricts the cultivation of relevant technical talents. Summary of the Invention

[0004] In order to solve the above problems, the present invention provides an isolation perfusion system.

[0005] An isolation perfusion system and a control method provided by the present invention adopt the following technical solutions: An isolation perfusion system includes a frame, on which a main pipeline is arranged. The main pipeline is connected to a liquid storage tank through a hose and a pump body; a pressure measuring flange is arranged on the main pipeline, an orifice plate is installed inside the pressure measuring flange, and both sides of the pressure measuring flange are also connected to a liquid separation cylinder through pressure measuring conduits. The liquid separation cylinder is connected to a multi-valve group through a conduit, the multi-valve group is connected to a pressure transmitter, a drain pipe is also connected to the liquid separation cylinder, a pressure guiding pipe is also connected to the multi-valve group, the pressure guiding pipe is connected to a medium tank through a pump body, and control valves are arranged on the pressure measuring conduits, the drain pipe, and the pressure guiding pipe.

[0006] Through the above technical solution, by setting core components such as a frame, a main pipeline, a pressure measuring flange, a liquid separation cylinder, a multi-valve group and a pressure transmitter, modular integration of the industrial instrument isolation perfusion process is achieved. An orifice plate is installed in the pressure measuring flange. Combined with the linkage design of the pressure measuring conduit and the liquid separation cylinder, it can accurately measure the change of fluid pressure in the pipeline. The configuration of the multi-valve group and the pressure guiding pipe supports flexible control of the medium flow direction, and the cooperation of the drain pipe and the liquid separation cylinder can quickly remove impurities or air bubbles in the system. The overall structure simplifies the complex pipeline of the traditional perfusion system, significantly improves the operation efficiency and maintenance convenience, and is especially suitable for fault simulation and practical operation training in teaching and training.

[0007] As a preference of the present invention, a bubble generator is further provided on the frame, and the bubble generator is connected to the liquid separation cylinder through a bubble conduit.

[0008] Through the above technical solution, by adding a bubble generator on the frame and connecting it to the liquid separation cylinder, the system can actively simulate the fault scenario of bubble interference in the pipeline. The bubble generator injects controllable bubbles into the liquid separation cylinder through the bubble conduit, enabling trainees to visually observe the influence of bubbles on the readings of the pressure transmitter and learn the operation method of removing bubbles through the drain pipe. This design fills the gap that traditional equipment cannot simulate dynamic faults, greatly improves the interactivity and authenticity of teaching and training, and helps to cultivate the ability of trainees to solve practical problems.

[0009] As a preference of the present invention, a drain collection bucket is further provided on the frame, the drain pipe is connected to the drain collection bucket, and an outlet and a valve are further provided on the drain collection bucket.

[0010] Through the above technical solution, the connection design of the drain collection bucket and the drain pipe realizes the centralized recovery and environmental protection treatment of the system waste liquid. The drain pipe leads the impurities or waste liquid in the liquid separation cylinder into the collection bucket, and the outlet and the valve provided on the bucket body facilitate regular cleaning. This structure not only avoids environmental pollution caused by traditional manual liquid discharge, but also strengthens the trainees' awareness of standardized operation through the visual waste liquid collection process, and at the same time meets the requirements of clean production in the industrial field.

[0011] As a preference of the present invention, the main pipeline is fixed by a clamp to a connection seat, the connection seat is arranged on the frame, and the connection seat can move and be locked on the frame.

[0012] Through the above technical solution, the fixing method of the main pipeline by a clamp to a movable connection seat significantly improves the disassembly and assembly efficiency of the pressure measuring flange. The sliding design of the connection seat on the frame allows the operator to quickly adjust the flange position, and ensures the system stability after locking. This structure solves the drawback that traditional flange disassembly requires the whole machine to stop, and is especially suitable for frequent orifice plate replacement or blockage fault simulation in teaching scenarios, greatly reducing the time cost of practical training.

[0013] Preferably, a guide rail is provided on the frame, the connecting seat is arranged on the guide rail, and a locking bolt for locking the connecting seat to the guide rail is further provided on the connecting seat.

[0014] Through the above technical solution, the cooperation of the guide rail and the locking bolt further optimizes the moving precision and fixing reliability of the connecting seat. After the trainee slides the connecting seat along the guide rail to the target position, rigid fixation can be achieved through the locking bolt, avoiding measurement errors caused by displacement during the operation. This mechanical guiding structure simplifies the dependence on complex tools, enables the trainee to focus on the study of the perfusion principle, and at the same time ensures the durability of repeated disassembly and assembly of the system.

[0015] Preferably, a guide rail is provided on the frame, the connecting seat is arranged on the guide rail, a nut seat is further connected to the connecting seat, a driving motor is provided on the frame, the driving motor is connected to the nut seat through a lead screw, and the rotation of the lead screw can drive the nut seat to move along the direction of the guide rail.

[0016] Through the above technical solution, the driving motor realizes the electric movement of the connecting seat through the lead screw and nut mechanism, completely replacing the physical consumption of manual adjustment. The motor drives the lead screw to rotate, driving the nut seat to accurately displace along the guide rail, which not only improves the disassembly and assembly efficiency of the pressure measuring flange, but also reduces the safety risks in teaching through automated operation. This design is particularly suitable for high-frequency training scenarios and provides an expandable technical basis for the modular teaching of large industrial equipment.

[0017] Preferably, a liquid collection bucket is further provided at the bottom of the frame, the liquid collection bucket is arranged directly below the pressure measuring flange, and the liquid collection bucket is also connected to a liquid storage tank through a drain pipe.

[0018] Through the above technical solution, the liquid collection bucket is arranged directly below the pressure measuring flange and connected to the liquid storage tank to form a closed waste liquid recovery and circulation system. The liquid overflowing during the disassembly of the flange is intercepted by the collection bucket and automatically flows back to the liquid storage tank through the drain pipe, which not only keeps the operation site clean but also realizes the recycling of the isolation liquid. This design effectively solves the problem of liquid spillage in teaching demonstrations and strengthens the energy conservation and environmental protection awareness of trainees through the visual recycling process.

[0019] Preferably, guide wheels are further provided at the bottom of the frame, and the guide wheels can be locked.

[0020] Through the above technical solution, the design of the lockable guide wheels at the bottom of the rack endows the system with flexible mobility and workstation stability. The guide wheels facilitate the rapid transfer of the equipment between different teaching areas, and after being locked, they ensure that the rack has no displacement or vibration during the perfusion process. This dual-functional design not only meets the flexibility requirements of the laboratory space layout but also ensures the static accuracy of the system during pressure measurement, especially suitable for training scenarios with multi-class rotation.

[0021] In summary, the present invention includes at least one of the following beneficial technical effects: 1. Through modular design, the isolation perfusion system of the present invention simplifies the traditional complex industrial instrument perfusion process into an intuitive and operable teaching model. The main pipeline of the system is made of transparent acrylic material, enabling trainees to clearly observe the liquid flow path and the working state of the pressure measurement flange, facilitating the understanding of the pressure measurement principle. The interlocking design of the pressure measurement flange, liquid separation cylinder, multi-valve group, and pressure transmitter not only simulates the isolation perfusion process in a real industrial environment but also supports fault simulation training, such as orifice plate blockage, bubble interference, etc. By actively injecting bubbles through the bubble generator, trainees can directly observe the impact of bubbles on pressure measurement and learn how to eliminate faults through the drain pipe. In addition, the movable design of the connection seat on the guide rail makes the disassembly and assembly of the pressure measurement flange more convenient, facilitating repeated practice. The overall system reduces the operation threshold of traditional industrial equipment, enabling trainees to master key skills in a safe and controllable environment and significantly improving training efficiency.

[0022] 2. Through the design of the liquid collection bucket, sewage collection bucket, and circulation pipeline, the present invention realizes the automatic recovery and reuse of waste liquid, effectively reducing resource waste. The liquid overflowing when the pressure measurement flange is disassembled is intercepted by the collection bucket and flows back to the liquid storage tank through the drain pipe, avoiding polluting the operating environment. The connection between the drain pipe and the sewage collection bucket enables the centralized treatment of system impurities and waste liquid, meeting the requirements of industrial environmental protection. In addition, the introduction of the drive motor and the screw nut mechanism enables the automatic adjustment of the pressure measurement flange, reducing manual operation intensity and improving disassembly and assembly accuracy at the same time. The design of the lockable guide wheels at the bottom of the rack is convenient for equipment movement and ensures stability during operation. These optimizations not only reduce the maintenance cost of the system but also extend the service life of the equipment, making it particularly suitable for high-frequency teaching and training scenarios, while taking into account the practicality and economy of the industrial site. Description of the Drawings

[0023] Figure 1 is a schematic structural diagram of the isolation perfusion system according to Embodiment 1 of the present invention.

[0024] Figure 2 is a rear view schematic diagram of the isolation perfusion system according to Embodiment 1 of the present invention.

[0025] Figure 3It is a schematic structural diagram of the isolated perfusion system according to Embodiment 2 of the present invention.

[0026] Figure 4 It is a schematic structural diagram of the isolated perfusion system according to Embodiment 3 of the present invention.

[0027] Explanation of reference numerals: 1, frame; 2, main pipeline; 3, pressure measuring flange; 4, valve; 5, connecting seat; 6, clamp; 7, bubble generator; 8, sewage discharge pipe; 9, sewage collection bucket; 10, pressure guiding pipe; 11, pressure transmitter; 12, hose; 13, liquid storage tank; 14, delivery pump; 15, liquid collection bucket; 16, conduit; 17, liquid discharge pipe; 18, liquid separation cylinder; 19, multi-valve group; 20, bubble conduit; 21, guide rail; 22, drive motor; 23, lead screw; 24, nut seat; 25, pressure measuring conduit. Detailed implementation manners

[0028] The following further describes the present invention in detail with reference to the Figures 1-4 accompanying drawings.

[0029] Embodiment 1: Referring to the Figure 1 to the Figure 2 accompanying drawings, this embodiment discloses an isolated perfusion system, which is used for on-site training and teaching in enterprises. The isolated perfusion system includes a frame 1, and guide wheels (not shown in the figure) are further provided at the bottom of the frame 1, and the guide wheels can be locked. A main pipeline 2 is provided on the frame 1, and the main pipeline 2 is connected to a liquid storage tank 13 through a hose 12 and a delivery pump 14; a pressure measuring flange 3 is provided on the main pipeline 2, and valves 4 are further provided on the main pipeline 2 on both sides of the pressure measuring flange 3. The communication between the main pipeline 2 and the liquid storage tank 13 can be closed through the valves 4, and an orifice plate is installed in the pressure measuring flange 3. In this embodiment, the main pipeline 2 is made of transparent acrylic material, and a liquid for simulation (generally made of colored, non-toxic and harmless material) is provided in the liquid storage tank 13.

[0030] The main pipeline 2 is fixed to the connecting seat 5 through a clamp 6. The connecting seat 5 is provided on the frame 1, and the connecting seat 5 can move and be locked on the frame 1. Specifically: a guide rail 21 is provided on the frame, the connecting seat 5 is provided on the guide rail 21, and a locking bolt for locking the connecting seat 5 to the guide rail 21 is further provided on the connecting seat 21.

[0031] When it is necessary to disassemble the pressure measuring flange 3, first close the valve 4 on the main pipeline 2, loosen the fixing bolts on the pressure measuring flange 3, then loosen the locking bolts on the connecting seat 5 and the guide rail 21, and move the connecting seat 5, so that the pressure measuring flange 3 can be opened.

[0032] On both sides of the pressure measuring flange 3, a liquid separation cylinder 18 is also connected through a pressure measuring catheter 25. The liquid separation cylinder 18 is connected to a multi-valve group 19 through a catheter 16. The multi-valve group 19 is connected to a pressure transmitter 11. A sewage discharge pipe 8 is also connected to the liquid separation cylinder 18. A pressure guiding pipe 10 is also connected to the multi-valve group 19. The pressure guiding pipe 10 is connected to a medium tank through a pump body. Control valves are provided on the pressure measuring catheter 25, the sewage discharge pipe 8, and the pressure guiding pipe 10.

[0033] A bubble generator 7 is also provided on the frame 1. The bubble generator 7 is connected to the liquid separation cylinder 18 through a bubble catheter 20.

[0034] A sewage collection bucket 9 is also provided on the frame 1. The sewage discharge pipe 8 is connected to the sewage collection bucket 9. An outlet and a valve are also provided on the sewage collection bucket 9.

[0035] The training and teaching work process of the isolation perfusion system in this embodiment is as follows: 1. Basic operation mode (normal perfusion) System startup preparation: Check the isolation liquid storage in the liquid storage tank 13, confirm that the sewage collection bucket 9 is empty, lock the guide wheels of the frame, connect the power supply and the air source, initialize the system through the control panel, and start the delivery pump 14.

[0036] Standard perfusion demonstration: Observe the liquid flow path of the main pipeline 2 → pressure measuring flange 3 → liquid separation cylinder 18; Demonstrate the switch combinations of the multi-valve group 19 to control the flow of the isolation liquid to the pressure transmitter 11; Record the data of the pressure transmitter and verify the system tightness Pipeline emptying training: Operate the valve of the sewage discharge pipe 8 to simulate the liquid discharge process during maintenance; Demonstrate the recycling process of the waste liquid in the liquid collection bucket 15 back to the liquid storage tank.

[0037] 2. Fault simulation mode Orifice plate blockage fault drill: Disassembly training: The trainee loosens the locking bolt on the connecting seat 5, moves the connecting seat 5 along the guide rail 21, and takes out the orifice plate in the pressure measuring flange 3.

[0038] Blockage simulation: Apply glue or insert foreign objects on the spare orifice plate in advance.

[0039] Fault phenomenon: After reinstalling the blocked orifice plate, run the system and observe the abnormal data of the pressure transmitter and the flow rate change.

[0040] Bubble interference experiment: Start the bubble generator 7, inject bubbles into the liquid separation cylinder 18 through the bubble catheter 20, compare the reading fluctuations of the pressure transmitter 11 in the normal / bubble-containing state, and demonstrate the operation method of removing bubbles through the sewage discharge pipe (8).

[0041] 3. System maintenance teaching Quickly replace the damaged hose 12; simulate the leakage of the pressure guiding pipe 10 and use soapy water to detect the leakage point; calibrate the matching relationship between the pressure transmitter 11 and the multi-valve group 19.

[0042] Embodiment 2: Refer to Figure 3 , the rest of this embodiment is the same as that of Embodiment 1. The difference is that in this embodiment, in order to disassemble the pressure measuring flange 3 during the simulation of the orifice plate blockage fault drill, ensure the cleanliness of the site, and prevent the liquid in the main pipeline 2 from spilling everywhere, in this embodiment, a liquid collecting bucket 15 is further provided on the frame 1. The liquid collecting bucket 15 is arranged directly below the pressure measuring flange 3, and the liquid collecting bucket 15 is also connected to the liquid storage tank 13 through a drain pipe 17.

[0043] When it is necessary to disassemble the pressure measuring flange 3, the liquid flowing out from the pressure measuring flange 3 inside the main pipeline 2 is collected through the liquid collecting bucket 15 and finally collected and returned to the liquid storage tank 13 through the drain pipe 17, ensuring the cleanliness of the site.

[0044] Embodiment 3: Refer to Figure 4 , the rest of this embodiment is the same as that of Embodiment 2. The difference is that a guide rail 21 is provided on the frame, the connecting seat 5 is arranged on the guide rail 21, a nut seat 24 is further connected to the connecting seat, a driving motor 22 is also provided on the frame 1, the driving motor 22 is connected to the nut seat 24 through a lead screw 23, and the rotation of the lead screw 23 can drive the nut seat 24 to move along the direction of the guide rail 21.

[0045] When it is necessary to disassemble the pressure measuring flange 3, first close the valve 4 on the main pipeline 2, loosen the fixing bolts on the pressure measuring flange 3, then start the driving motor 22, drive the lead screw 23 to rotate through the rotation of the driving motor 22, thereby driving the nut seat 24 to move, and further driving the pressure measuring flange 3 to separate. The whole process is highly efficient.

[0046] The above are all the preferred embodiments of the present invention, and the protection scope of the present invention is not limited accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of the present invention should be covered within the protection scope of the present invention.

Claims

1. An isolated perfusion system, characterized in that: It includes a frame (1), on which a main pipeline (2) is provided. The main pipeline (2) is connected to a liquid storage tank (13) through a hose (12) and a delivery pump (14). A pressure measuring flange (3) is provided on the main pipeline (2). An orifice plate is installed inside the pressure measuring flange (3). Both sides of the pressure measuring flange (3) are also connected to a liquid separation cylinder (18) through pressure measuring conduits (25). The liquid separation cylinder (18) is connected to a multi-valve group (19) through a conduit (16). The multi-valve group (19) is connected to a pressure transmitter (11). A drain pipe (8) is also connected to the liquid separation cylinder (18). A pressure guiding pipe (10) is also connected to the multi-valve group (19). The pressure guiding pipe (10) is connected to a medium tank through a pump body. Control valves are provided on the pressure measuring conduits (25), the drain pipe (8), and the pressure guiding pipe (10).

2. The isolated perfusion system according to claim 1, characterized in that: A bubble generator (7) is also provided on the frame (1). The bubble generator (7) is connected to the liquid separation cylinder (18) through a bubble conduit (20).

3. The isolated perfusion system according to claim 1, wherein: A drain collection bucket (9) is also provided on the frame (1). The drain pipe (8) is connected to the drain collection bucket (9). An outlet and a valve are also provided on the drain collection bucket (9).

4. The isolated perfusion system according to claim 1, wherein: The main pipeline (2) is fixed to a connection seat (5) through a clamp (6). The connection seat (5) is provided on the frame (1), and the connection seat (5) can move and be locked on the frame (1).

5. The isolated perfusion system according to claim 4, wherein: A guide rail (21) is provided on the frame. The connection seat (5) is arranged on the guide rail (21). A locking bolt for locking the connection seat (5) to the guide rail (21) is also provided on the connection seat (5).

6. The isolated perfusion system according to claim 1, wherein: A guide rail (21) is provided on the frame. The connection seat (5) is arranged on the guide rail (21). A nut seat (24) is also connected to the connection seat. A driving motor (22) is also provided on the frame (1). The driving motor (22) is connected to the nut seat (24) through a lead screw (23). Rotation of the lead screw (23) can drive the nut seat (24) to move along the direction of the guide rail (21).

7. The isolated perfusion system according to claim 1, wherein: A liquid collection bucket (15) is also provided on the frame. The liquid collection bucket (15) is arranged directly below the pressure measuring flange (3). The liquid collection bucket (17) is also connected to the liquid storage tank (13) through a drain pipe.

8. The isolated perfusion system according to claim 1, wherein: Guide wheels are also provided at the bottom of the frame (1), and the guide wheels can be locked.

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