Simulation device and method for evaluating aerosol inhalation of human body

Abstract

The invention discloses a simulation device and method for human body aerosol inhalation assessment, and relates to the technical field of human body aerosol inhalation assessment, and the method comprises the following steps: human body posture simulation: according to a scene to be assessed, selecting and switching postures of a simulated human body, the postures including a standing posture, a sitting posture and a lying posture, aerosol inhalation exposure conditions of a human body in different postures are simulated; human body respiration control, wherein the respiration frequency and ventilation capacity of the simulated human body are adjusted. By introducing the human body posture model, the breathing mode control unit and the body temperature adjusting unit, airflow changes and aerosol inhalation risks of the human body under different postures and body temperatures are accurately simulated, and the limitation of the prior art is overcome. The aerosol sampling and evaluation process is monitored in real time and dynamically adjusted, it is ensured that the evaluation result is closer to the actual physiological state of the human body and is more accurate and real-time, the method is particularly suitable for high-temperature and low-temperature environments and rapidly-changed aerosol concentration, and accurate support is provided for public health and environment monitoring.

Description

Technical Field

[0001] The present invention relates to the technical field of human aerosol inhalation assessment, and particularly relates to a simulation device and method for human aerosol inhalation assessment. Background Art

[0002] With the increasing severity of aerosol pollution in industry, healthcare, and daily life, the impact of aerosol inhalation exposure on human health has become an important topic in the field of public health. When evaluating the risk of human aerosol inhalation exposure, the existing technologies mainly adopt two methods: one is to perform simulation calculations by developing aerosol diffusion simulation software and human respiratory models, and the other is to directly collect aerosols in the air using a multi-stage aerosol sampler and evaluate the risk of human inhalation exposure by establishing a mathematical model. Although these methods can provide preliminary risk assessments in certain environments, they still face many limitations and challenges.

[0003] Firstly, the existing software simulation-based risk assessment methods usually require complex aerosol diffusion models and human respiratory models. The computational workload of these models is huge, and the operation process is cumbersome. Especially when simulating physiological factors such as human posture, breathing frequency, and body temperature in a simulation environment, the adjustment and calculation of the models are even more complex. In addition, the models usually lack accurate simulation of the actual respiratory tract characteristics of the human body, resulting in inaccurate assessment results in specific situations. On the other hand, although the risk assessment method based on an aerosol sampler can directly measure the concentration of aerosols in the environment, such methods usually need to be carried out in a complex experimental environment, with difficult operation and poor real-time performance. The deployment and data processing processes of the sampler are often cumbersome, and it is also difficult to consider the adsorption and filtration effects of different parts of the human body on aerosols. Therefore, there is a large room for improvement in the simplicity, real-time performance, and accuracy of the existing assessment methods, and it is difficult to meet the requirements of efficient and accurate aerosol exposure risk assessment.

[0004] The above information disclosed in the background art section is only used to enhance the understanding of the background of the present disclosure, and thus it may include information that does not constitute the prior art known to those of ordinary skill in the art. Summary of the Invention

[0005] The object of the present invention is to provide a simulation device and method for human aerosol inhalation assessment. By introducing a human body posture model, an adjustable breathing mode control unit and a body temperature control unit, the air flow changes of the human body in different postures and body temperature states are accurately simulated, thereby overcoming the limitations in the prior art that cannot comprehensively consider the influence of posture and body temperature on aerosol inhalation. By adjusting the breathing flow rate and aerosol distribution, the present invention improves the accuracy and authenticity of risk assessment, and is particularly applicable to high-temperature and low-temperature environments. Combined with a real-time aerosol sampling and monitoring system, it can dynamically monitor the change of aerosol concentration, ensure that the assessment results are timely and accurate, and meet the requirements of rapid-response public health and environmental monitoring to solve the problems in the above-mentioned background technology.

[0006] To achieve the above object, the present invention provides the following technical solutions: A simulation method for human aerosol inhalation assessment, comprising the following steps: Human body posture simulation: According to the required assessment scenario, select and switch the posture of the simulated human body. The postures include standing, sitting and lying postures, and the aerosol inhalation exposure of the simulated human body in different postures is simulated; Human body breathing control: By adjusting the breathing frequency and ventilation volume of the simulated human body, control the air flow characteristics of the air inlet and outlet, and simulate the inhalation and distribution process of aerosol by the air flow of human breathing; Body temperature control: Adjust the body temperature of the simulated human body, simulate the air flow change on the human body surface, and improve the accuracy of inhalation exposure risk assessment through the interaction between the air flow formed by body temperature heating and the aerosol; Aerosol concentration monitoring: Set a plurality of air guide holes on the simulated respiratory tract, and monitor the aerosol concentration in the respiratory tract and its external environment in real time to obtain aerosol data in different particle size ranges; Aerosol sampling: Collect the aerosol passing through the simulated human respiratory tract through a quickly disassembled aerosol collection tube for evaluating the human inhalation exposure risk and further analyzing the absorption dose of the aerosol.

[0007] Preferably, the human body posture simulation step includes realizing the rapid posture switching of the simulated human body through a mechanical driving device. The driving device can enable the simulated human body to complete the conversion from standing to sitting and then to lying posture within a set time, and in each posture, the breathing mode and body temperature control of the human body can be independently adjusted to evaluate the influence of different postures on aerosol inhalation exposure.

[0008] Preferably, the human body breathing control step includes setting an adjustable breathing frequency and ventilation volume control unit. The control unit can adjust the inhalation and exhalation rates of the simulated human body in different assessment scenarios to simulate the breathing rhythm of the human body under various environmental conditions, so as to analyze the inhalation amount and risk level of aerosol under different breathing modes.

[0009] Preferably, the aerosol concentration monitoring step further includes arranging a plurality of aerosol counters with different particle size segments in the respiratory tract of the simulated human body to continuously monitor the aerosol concentration in different particle size segments, and dynamically adjusting the risk assessment parameters according to the concentration change to improve the analysis accuracy of the influence of different aerosol particle sizes on human inhalation exposure.

[0010] Preferably, the aerosol sampling step includes designing a detachable aerosol collection tube on the respiratory tract of the simulated human body. The collection tube can regularly or continuously collect the aerosol passing through different parts of the human body, and analyze the collected aerosol to detect its particle size distribution, concentration, deposition characteristics, etc., so as to calculate the dose of the aerosol actually inhaled by the simulated human body and its potential impact on health.

[0011] Preferably, the body temperature control step forms a real airflow pattern at the mouth and nose of the human body by simulating the change of the airflow on the human body surface. This airflow simulates the heating effect of body temperature on air flow and affects the movement trajectory of the aerosol in the respiratory tract. The body temperature control step includes adjusting the airflow temperature, speed and humidity to accurately simulate the aerosol inhalation exposure risk of the human body under different body temperature conditions.

[0012] Preferably, the human breathing control step includes designing an adjustable filter in the respiratory tract of the simulated human body. The filter adjusts its filtering effect on aerosols with different particle sizes according to the size and shape of the actual human respiratory tract, simulates the adsorption, deposition and filtering effects of the human respiratory tract on aerosols during inhalation, so as to evaluate the aerosol inhalation exposure risk of different parts of the human body.

[0013] Preferably, the aerosol sampling step further includes using an aerosol sampling unit to sample the aerosol in the respiratory tract of the simulated human body, and continuously measuring the concentration change of the aerosol through a particle counter. According to the distribution of the aerosol in different parts, the inhalation risk of the aerosol and its potential impact on human health are evaluated to ensure the efficiency and accuracy of the evaluation results.

[0014] Preferably, the human body posture simulation step simulates the airflow patterns and the deposition process of aerosols in the respiratory tract in various environments in different postures of standing, sitting and lying, and evaluates the degree of influence of human body posture changes on aerosol inhalation by calculating the difference in inhalation exposure risk under different human body postures.

[0015] A simulation device for human aerosol inhalation assessment, comprising a human body posture simulation unit, a human breathing control unit, a body temperature control unit, an aerosol concentration monitoring unit, an aerosol sampling unit and a control system; The human body posture simulation unit is used to simulate and switch the three postures of the human body, namely standing, sitting and lying, simulate the airflow changes and aerosol inhalation conditions in different postures, and can quickly switch the human body posture according to the evaluation requirements; A human respiratory control unit, which is used to adjust the breathing frequency and ventilation volume of the simulated human body, and adjust the speed and volume of the air flow through the air inlet and outlet at the mouth and nose to simulate the real breathing process of the human body, and works in cooperation with the human body posture simulation unit; A body temperature control unit, which is used to adjust the body temperature of the simulated human body, control the temperature of the air flow on the body surface, and form a simulated air flow at the mouth and nose of the human body to simulate the characteristics of the real environmental air flow and aerosol distribution; An aerosol concentration monitoring unit, including aerosol counters in multiple particle size segments, which is used to monitor the concentration of aerosols in the respiratory tract and the surrounding environment in real time, and feedback to the evaluation system to dynamically adjust the risk assessment parameters; An aerosol sampling unit, including a detachable aerosol collection tube, which collects aerosol samples passing through the simulated human respiratory tract for subsequent analysis in order to accurately evaluate the aerosol dose inhaled by the human body and the risk of inhalation exposure; A control system, which is used to cooperate in controlling the working processes of the above-mentioned units, supports rapid switching of postures, adjustment of breathing frequency, body temperature regulation, aerosol concentration monitoring and sampling processes, and ensures the accuracy and real-time nature of the evaluation process.

[0016] In the above technical solution, the technical effects and advantages provided by the present invention are as follows: By introducing a human body posture model and a breathing mode control unit, the present invention simulates the aerosol inhalation exposure risk of the human body in different postures, solves the limitation in the prior art that the influence of posture changes on aerosol inhalation cannot be comprehensively considered, and can adjust the aerosol distribution characteristics in real time by accurately simulating the air flow changes of the human body in different postures, thereby improving the accuracy of the human aerosol inhalation exposure risk assessment. Whether standing, sitting or lying down, the evaluation results can be made more in line with the aerosol exposure situation of the human body in real life by adjusting the breathing flow rate and aerosol distribution, ensuring the authenticity and reliability of the evaluation results.

[0017] By introducing an adjustable human body temperature control unit, the present invention simulates the air flow changes of the human body in different body temperature states, solves the technical gap in the prior art that the influence of body temperature on the aerosol inhalation exposure risk cannot be considered, and can adjust the speed and direction of the air flow by precisely controlling the simulated human body temperature, truly reproducing the influence of body temperature on the aerosol inhalation exposure risk. Especially in different environmental temperatures, the breathing air flow and aerosol diffusion characteristics of the human body will be different. This innovative technology greatly improves the accuracy of the human aerosol inhalation exposure risk assessment, especially suitable for exposure assessments in high-temperature or low-temperature environments, and provides accurate data support for health risk assessments under different environmental conditions.

[0018] By designing an advanced aerosol sampling unit and a real-time monitoring system, the present invention solves the problems of lagging aerosol collection and evaluation and cumbersome operation in the prior art. Through a detachable aerosol sampling tube and a particle counter, the particle size distribution and concentration change of aerosol can be detected in real time during the experiment. This technological innovation enables continuous monitoring and rapid feedback of the aerosol concentration in the human respiratory tract, thereby adjusting the operating status of the simulation device in real time, such as parameters like respiratory rate and body temperature. This function of real-time monitoring and dynamic adjustment makes the risk assessment process more flexible, capable of promptly responding to changes in aerosol concentration, thus improving the accuracy and timeliness of the assessment results, and is particularly applicable to fields such as public health and environmental monitoring that require rapid response. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] To more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments recorded in the present invention, and those of ordinary skill in the art can also obtain other drawings based on these drawings.

[0020] Figure 1 It is a flowchart of a simulation method for human aerosol inhalation assessment of the present invention.

[0021] Figure 2 It is a schematic diagram of unit modules of a simulation device for human aerosol inhalation assessment of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0022] Now, the exemplary embodiments will be described more comprehensively with reference to the drawings. However, the exemplary embodiments can be implemented in various forms and should not be construed as limited to the examples set forth herein; rather, these exemplary embodiments are provided so that the present disclosure will be more thorough and complete, and will fully convey the concept of the exemplary embodiments to those skilled in the art.

[0023] The present invention provides a simulation method for human aerosol inhalation assessment as shown in Figure 1 and includes the following steps: Human posture simulation: According to the required assessment scenario, select and switch the posture of the simulated human body. The postures include standing, sitting, and lying down, and simulate the aerosol inhalation exposure of the simulated human body in different postures; Human respiration control: By adjusting the respiratory rate and ventilation volume of the simulated human body, control the airflow characteristics of the air inlet and outlet, and simulate the inhalation and distribution process of aerosol by the airflow of human respiration; Body temperature control: Adjust the body temperature of the simulated human body, simulate the airflow change on the body surface of the human body, and improve the accuracy of the inhalation exposure risk assessment through the interaction between the airflow formed by body temperature heating and the aerosol; Aerosol concentration monitoring: Multiple air vents are set on the simulated respiratory tract to monitor the aerosol concentration inside and outside the respiratory tract in real time, and obtain aerosol data in different particle size ranges. Aerosol sampling: Through a quickly detachable aerosol collection tube, the aerosol passing through the simulated human respiratory tract is collected to evaluate the inhalation exposure risk of the human body and further analyze the absorption dose of the aerosol.

[0024] Embodiment 1: Simulation method of human body posture and breathing control unit In this embodiment, the key technology of the simulation device lies in the accurate simulation of different human body postures (standing, sitting, lying). To achieve this goal, a mechanical drive system is designed, which combines a high-precision servo motor and a pneumatic component, and drives the simulated human to adjust the posture through a computer control system. The system accurately controls the angles and directions of the torso and limbs according to the preset posture transformation requirements. Each time the posture is changed, the system monitors and adjusts the rotation speed and angle of the servo motor in real time through sensors to ensure that the simulated human body meets the set posture requirements.

[0025] In the standing posture, the simulated human maintains a natural upright state, simulating the body shape, center of gravity and mechanical characteristics of the human body. The switching between the sitting and lying postures is achieved through a hydraulic support structure. The hydraulic system can be accurately adjusted according to the height and weight of the simulated human body to achieve rapid and stable changes in posture. This process not only ensures the stability of the simulated human body, but also avoids the influence of human body posture changes on the airflow and aerosol distribution.

[0026] In addition, a series of optimizations have also been carried out on the breathing control unit in this embodiment. The breathing control system of the simulated human body adopts an air flow regulation unit, which accurately simulates the breathing conditions of the human body in different activity states by adjusting parameters such as air flow rate, breathing frequency, and tidal volume. Specifically, the breathing frequency and ventilation volume of the simulated human body are different when standing, sitting and lying. In the standing state, the simulated human will simulate the breathing frequency and volume of normal rest; while in the lying or sitting state, the simulated human body may adjust to a more relaxed breathing mode. Sensors are equipped in the breathing control unit to sense the changes in air flow in real time and adjust the parameters of the control system to ensure the accuracy of simulated breathing in each posture.

[0027] To further improve the accuracy of risk assessment, the aerosol distribution pattern of the simulation device will be adjusted accordingly according to the changes in human body posture and breathing pattern. For example, in the standing position, the diffusion path and deposition pattern of aerosols are different from those in the sitting or lying positions because the breathing airflow is stronger when the human body is standing, and there are differences between the direction of the airflow and the movement of aerosols under the action of gravity. The change in the aerosol inhalation risk caused by this posture change can be measured and fed back in real time through the aerosol monitoring unit in the simulation device, so as to provide high-precision inhalation exposure assessment data.

[0028] The advantage of this embodiment is that it can accurately control and evaluate the inhalation exposure risk of the human body in different postures through mechanical and airflow simulation technologies. Its simulation results provide more reliable data support for the research of aerosol exposure risk, public health risk assessment, and the safety detection of related products.

[0029] Embodiment 2: Body temperature control and airflow simulation; This embodiment focuses on solving the correlation between the airflow distribution and aerosol exposure risk assessment of the simulated human body at different body temperatures. To achieve this goal, the simulation device is equipped with a body temperature control unit, which simulates the influence of human body temperature changes on airflow and aerosol distribution through an electrothermal film heating device. The simulation device can be freely adjusted within a set body temperature range (such as between 35°C and 38°C) to ensure that it can simulate various changes in human body temperature in normal living environments and different working states.

[0030] When the simulated human body temperature changes, the airflow distribution on the body surface will also change accordingly, thereby affecting the aerosol distribution. To accurately simulate this process, this device adopts an airflow heating system, which heats the airflow at the mouth and nose of the human body to simulate the influence of human body temperature changes on the breathing airflow. For example, when the body temperature is low, the airflow speed is low and the aerosol distribution is relatively uniform; while when the body temperature is high, due to the upward movement of hot air, the airflow speed increases, and the aerosol may be distributed along different airflow paths, changing its deposition characteristics and inhalation risk.

[0031] The body temperature control unit of this embodiment adopts an efficient temperature control module, which is linked with a temperature sensor and an airflow regulating device to monitor and adjust the body surface temperature of the simulated human body in real time. This system can adjust the body surface temperature of the human body in a very short time and form a simulated airflow by heating the air. This process not only simulates the influence of body temperature changes on the breathing airflow, but also simulates the airflow characteristics of the human body in different body temperature states through the airflow control system, enhancing the diversity of the aerosol distribution pattern.

[0032] To further improve the accuracy of the simulation results, this embodiment also designs a dynamic air flow regulating device. By adjusting the air flow speed and direction at the simulated human breathing port, it further controls the distribution and deposition pattern of aerosols in the respiratory tract. This design ensures a high correlation between the aerosol concentration during the simulation and the actual inhalation amount of the human body, ensuring the authenticity and reliability of the risk assessment results.

[0033] By simulating the distribution patterns of air flow and aerosols at different body temperatures, this embodiment can provide more parameter support for the assessment of aerosol inhalation exposure risks, and enhance the accuracy of the assessment of human exposure risks in extreme environments (such as high-temperature environments), and can provide a more scientific and reliable assessment basis for the public health field.

[0034] Embodiment 3: Aerosol sampling and analysis method; In this embodiment, a detachable aerosol sampling tube is designed and installed at different parts of the simulated human respiratory tract for collecting and analyzing the aerosols passing through these parts. The design of the sampling tube aims to accurately collect the aerosol concentrations at various parts of the respiratory tract according to the breathing characteristics of the simulated human body. Multiple precision filters are distributed inside the aerosol sampling tube, which can collect aerosol particles of different particle sizes according to the requirements of different particle size ranges. For example, the filters can collect aerosols in different particle size ranges such as 0.3μm, 1μm, and 5μm, and store or export these particles for further analysis.

[0035] During the sampling process, the design of the sampling tube enables the rapid and accurate collection of aerosols. Through the micro sensors embedded in the pipeline, during the simulated human inhalation process, the changes in the air flow speed, direction, and aerosol concentration will be monitored and recorded in real time. The collected aerosol samples are analyzed for particle size distribution through a micro particle counter to obtain the aerosol concentration data of different particle sizes, and further evaluate the deposition amount of aerosols in the respiratory tract and its potential impact on human health through a calculation model.

[0036] During the sampling process, the air flow system inside the device ensures the collection accuracy of aerosols by guiding the gas flow. The sampling tube is connected to the respiratory tract system of the simulated human body, and can efficiently extract aerosols from different parts of the simulated human body to ensure that the aerosol concentration at each part can be accurately evaluated. The sampling tube is designed to be quickly detachable for easy replacement or cleaning in different experiments. By sampling multiple times at different parts and different experimental environments, the simulation device can provide a large amount of accurate aerosol concentration data to provide high-quality data support for subsequent risk assessments.

[0037] The advantage of this embodiment lies in its efficient and precise aerosol sampling method, which not only improves the accuracy of aerosol collection but also, through the real-time monitoring system, ensures that the data on simulated human aerosol exposure are highly representative and reliable. In addition, the innovative design of the aerosol sampling and analysis method further improves the accuracy of risk assessment, especially in the fields of aerosol exposure research and public health, where it has broad application prospects.

[0038] By introducing a human posture model and a breathing pattern control unit, the present invention simulates the aerosol inhalation exposure risk of the human body in different postures (such as standing, sitting, and lying down), thus solving the limitation in the prior art that the influence of posture changes on aerosol inhalation cannot be comprehensively considered. In traditional risk assessment methods, the influence of human posture on respiratory airflow and aerosol distribution is often ignored, resulting in a large error in the assessment results. By accurately simulating the airflow changes of the human body in different postures, the present invention can adjust the aerosol distribution characteristics in real time, thereby improving the accuracy of the assessment of the human inhalation exposure risk. Whether standing, sitting, or lying down, the present invention can make the assessment results more in line with the actual aerosol exposure situation of the human body in real life by adjusting the breathing flow rate and aerosol distribution, thus ensuring the authenticity and reliability of the assessment results.

[0039] By introducing an adjustable human body temperature control unit, the present invention simulates the airflow changes of the human body in different body temperature states, solving the technical gap in the prior art that the influence of body temperature on the aerosol inhalation exposure risk cannot be considered. Traditional assessment methods cannot simulate the interaction between human body temperature and airflow, which in turn affects the deposition and distribution of aerosols, resulting in a deviation in the assessment results. By precisely controlling the simulated human body temperature, the present invention can adjust the speed and direction of the airflow, truly reproducing the influence of body temperature on the aerosol inhalation exposure risk. Especially in different environmental temperatures, the respiratory airflow and aerosol diffusion characteristics of the human body will be different. This innovative technology of the present invention greatly improves the accuracy of the assessment of the human aerosol inhalation exposure risk, especially applicable to the exposure assessment in high-temperature or low-temperature environments, providing accurate data support for the health risk assessment under different environmental conditions.

[0040] The present invention solves the problems of lagging aerosol collection and evaluation and cumbersome operation in the prior art by designing an advanced aerosol sampling unit and a real-time monitoring system. Traditional aerosol monitoring methods usually cannot achieve real-time data collection, resulting in the lack of timeliness of evaluation results and making it difficult to cope with the rapidly changing aerosol concentration environment. However, the present invention can detect the particle size distribution and concentration change of aerosols in real time during the experiment through a detachable aerosol sampling tube and a particle counter. This technological innovation enables continuous monitoring and rapid feedback of the aerosol concentration in the human respiratory tract, thereby adjusting the operating state of the simulation device in real time, such as parameters like breathing frequency and body temperature. This function of real-time monitoring and dynamic adjustment makes the risk assessment process more flexible, capable of promptly responding to the change of aerosol concentration, thus improving the accuracy and timeliness of the evaluation results, and is particularly applicable to fields such as public health and environmental monitoring that require rapid response.

[0041] The present invention provides a simulation device for human aerosol inhalation assessment as Figure 2 shown, which includes a human body posture simulation unit, a human body breathing control unit, a body temperature control unit, an aerosol concentration monitoring unit, an aerosol sampling unit, and a control system: The human body posture simulation unit is used to simulate and switch three postures of the human body, namely standing, sitting, and lying, simulate the airflow changes and aerosol inhalation conditions in different postures, and can quickly switch the human body posture according to the evaluation requirements; The human body breathing control unit is used to adjust the breathing frequency and ventilation volume of the simulated human body, and adjust the speed and volume of the airflow through the air inlet and outlet at the mouth and nose to simulate the real breathing process of the human body, and works in coordination with the human body posture simulation unit; The body temperature control unit is used to adjust the body temperature of the simulated human body, control the body surface airflow temperature, and form a simulated airflow at the mouth and nose of the human body to simulate the real environmental airflow and aerosol distribution characteristics; The aerosol concentration monitoring unit includes aerosol counters segmented by multiple particle sizes, which are used to monitor the aerosol concentration in the respiratory tract and the surrounding environment in real time, and feedback to the evaluation system to dynamically adjust the risk assessment parameters; The aerosol sampling unit includes a detachable aerosol collection tube, which collects aerosol samples passing through the simulated human respiratory tract for subsequent analysis in order to accurately evaluate the aerosol dose inhaled by the human body and the risk of inhalation exposure; The control system is used to coordinately control the working processes of the above-mentioned units, support rapid posture switching, breathing frequency adjustment, body temperature regulation, aerosol concentration monitoring, and sampling processes, and ensure the accuracy and timeliness of the evaluation process; A simulation method for human aerosol inhalation assessment provided by an embodiment of the present invention is implemented by the above-mentioned simulation device for human aerosol inhalation assessment. For the specific method and process of the simulation device for human aerosol inhalation assessment, please refer to the embodiments of the above-mentioned simulation method for human aerosol inhalation assessment, which will not be elaborated here.

[0042] Only some exemplary embodiments of the present invention have been described by way of illustration above. Undoubtedly, for those of ordinary skill in the art, without departing from the spirit and scope of the present invention, the described embodiments can be modified in various different ways. Therefore, the above drawings and description are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

[0043] It should be noted that in this article, if there are relational terms such as first and second, they are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "comprising an..." does not exclude the existence of additional identical elements in the process, method, article or device comprising the element.

[0044] It should be understood that in various embodiments of the present application, the sequence numbers of the above processes do not mean the order of execution is prior or subsequent. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation to the implementation process of the embodiments of the present application.

[0045] Those of ordinary skill in the art can realize that the units and algorithm steps of each example described in combination with the embodiments disclosed in this article can be implemented by electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are executed in a hardware or software manner depends on the specific application and design constraints of the technical solution. Professionals can use different methods to implement the described functions for each specific application, but such implementation should not be considered to exceed the scope of the present application.

[0046] Those skilled in the art can clearly understand that for the convenience and brevity of description, the specific working processes of the above-described systems, devices and units can refer to the corresponding processes in the foregoing method embodiments, which will not be elaborated here.

[0047] In several embodiments provided by this application, it should be understood that the disclosed systems, devices, and methods can be implemented in other ways. For example, the device embodiments described above are merely illustrative. For example, the division of the units is only a logical function division. In actual implementation, there can be other division methods. For example, multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point is that the displayed or discussed coupling, direct coupling, or communication connection between each other can be through some interfaces. The indirect coupling or communication connection of the devices or units can be in electrical, mechanical, or other forms.

[0048] The units described as separate components may or may not be physically separated. The components displayed as units may or may not be physical units, that is, they can be located in one place or distributed to multiple network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0049] In addition, in each embodiment of this application, each functional unit can be integrated in a processing unit, or each unit can exist physically alone, or two or more units can be integrated in one unit.

[0050] If the above functions are implemented in the form of software function units and sold or used as independent products, they can be stored in a computer-readable storage medium. Based on such an understanding, the technical solution of this application, in essence, or the part that contributes to the prior art, or a part of this technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions to enable a computer device (which can be a personal computer, a server, or a network device, etc.) to execute all or part of the steps of the methods described in each embodiment of this application. The foregoing storage medium includes: various media that can store program codes such as USB flash drives, mobile hard disks, read-only memory (ROM), random access memory (RAM), magnetic disks, or optical discs.

[0051] As described above, it is only the specific implementation manner of this application, but the protection scope of this application is not limited thereto. Any person skilled in the art within the technical scope disclosed by this application can easily think of changes or substitutions, which should all be covered within the protection scope of this application. Therefore, the protection scope of this application should be subject to the protection scope of the claims.

[0052] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the various embodiments of the present invention.

Claims

1. A simulation method for human aerosol inhalation assessment, characterized in that, It includes the following steps: Human body posture simulation: According to the required evaluation scenario, select and switch the postures of the simulated human body. The postures include standing, sitting, and lying positions, and simulate the aerosol inhalation exposure of the human body in different postures; Human body breathing control: By adjusting the breathing frequency and ventilation volume of the simulated human body, control the airflow characteristics of the air inlet and outlet, and simulate the inhalation and distribution process of aerosol by the airflow of human breathing; Body temperature control: Adjust the body temperature of the simulated human body, simulate the airflow change on the body surface of the human body, and improve the accuracy of inhalation exposure risk assessment through the interaction between the airflow formed by body temperature heating and the aerosol; Aerosol concentration monitoring: Set multiple air vents on the simulated respiratory tract to monitor the aerosol concentration in the respiratory tract and its external environment in real time, and obtain aerosol data in different particle size ranges; Aerosol sampling: Collect the aerosol passing through the simulated human respiratory tract through a quickly detachable aerosol collection tube, which is used to evaluate the human inhalation exposure risk and further analyze the absorption dose of the aerosol.

2. The simulation method for human aerosol inhalation assessment according to claim 1, wherein The human body posture simulation step includes realizing the quick posture switching of the simulated human body through a mechanical driving device. The driving device can make the simulated human body complete the conversion from standing to sitting, and then to lying position within the set time, and in each posture, the breathing mode and body temperature control of the human body can be independently adjusted to evaluate the influence of different postures on aerosol inhalation exposure.

3. A simulation method for human aerosol inhalation assessment according to claim 1, characterized in that The human body breathing control step includes setting an adjustable breathing frequency and ventilation volume control unit. The control unit can adjust the inhalation and exhalation rates of the simulated human body in different evaluation scenarios, and simulate the breathing rhythm of the human body under various environmental conditions to analyze the inhalation amount and risk level of aerosol in different breathing modes.

4. A simulation method for human aerosol inhalation assessment according to claim 1, characterized in that, The aerosol concentration monitoring step further includes setting multiple aerosol counters with particle size segments in the respiratory tract of the simulated human body, which are used to monitor the aerosol concentration in different particle size ranges in real time, and dynamically adjust the risk assessment parameters according to the concentration change.

5. A simulation method for human aerosol inhalation assessment according to claim 1, characterized in that, The aerosol sampling step includes designing a detachable aerosol collection tube on the respiratory tract of the simulated human body. The collection tube can collect the aerosol passing through different parts of the human body regularly or in real time, and analyze the collected aerosol to calculate the dose of the aerosol actually inhaled by the simulated human body and its potential impact on health.

6. The simulation method for human aerosol inhalation assessment according to claim 1, characterized in that, The body temperature control step forms a real airflow pattern at the mouth and nose of the human body by simulating the change of the airflow on the body surface of the human body. The airflow simulates the heating effect of body temperature on air flow and affects the movement trajectory of aerosol in the respiratory tract; The body temperature control step includes adjusting the body surface temperature of the human body, simulating the air flow temperature, speed and humidity to accurately simulate the aerosol inhalation exposure risk of the human body under different body temperature conditions.

7. A simulation method for human aerosol inhalation assessment according to claim 1, wherein, The human body breathing control step includes designing an adjustable aerosol cutter in the respiratory tract of the simulated human body. The cutter adjusts the filtering effect on aerosols of different particle sizes according to the size and shape of the actual human respiratory tract, simulates the adsorption, deposition and filtering effects of the human respiratory tract on aerosols during inhalation, and evaluates the aerosol inhalation exposure risk of each part of the human body.

8. A simulation method for human aerosol inhalation assessment according to claim 1, characterized in that, The aerosol sampling step further includes using an aerosol sampling unit to sample the aerosol in the simulated human respiratory tract, and measuring the concentration change of the aerosol in real time through a particle counter. According to the distribution of the aerosol in different parts, the inhalation risk of the aerosol and its potential impact on human health are evaluated.

9. A simulation method for human aerosol inhalation assessment according to claim 1, characterized in that The human body posture simulation step simulates the airflow patterns and the deposition process of the aerosol in the respiratory tract in various environments in different postures of standing, sitting, and lying, and evaluates the degree of influence of the change in human body posture on aerosol inhalation by calculating the difference in inhalation exposure risk in different human body postures.

10. A simulation device for human aerosol inhalation assessment, which is used to implement the simulation method for human aerosol inhalation assessment described in any one of the above claims 1-9, characterized in that, It includes a human body posture simulation unit, a human body breathing control unit, a body temperature control unit, an aerosol concentration monitoring unit, an aerosol sampling unit, and a control system; The human body posture simulation unit is used to simulate and switch the three postures of the human body, namely standing, sitting, and lying, simulate the airflow changes and aerosol inhalation conditions in different postures, and quickly switch the human body posture according to the evaluation requirements; The human body breathing control unit is used to adjust the breathing frequency and ventilation volume of the simulated human body, and simulate the real breathing process of the human body through the changes in the speed and ventilation volume of the airflow at the air inlet and outlet at the mouth and nose, and work in coordination with the human body posture simulation unit; The body temperature control unit is used to adjust the body temperature of the simulated human body, control the surface airflow temperature, and form a simulated airflow at the mouth and nose of the human body to simulate the real environmental airflow and aerosol distribution characteristics; The aerosol concentration monitoring unit includes aerosol counters with multiple particle size segments, which are used to monitor the concentration of the aerosol in the respiratory tract and the surrounding environment in real time, and feedback to the evaluation system to dynamically adjust the risk assessment parameters; The aerosol sampling unit includes a detachable aerosol collection tube, which collects the aerosol sample passing through the simulated human respiratory tract for subsequent analysis, so as to accurately evaluate the aerosol dose inhaled by the human body and the risk of inhalation exposure; The control system is used to coordinate and control the working process of each unit, support rapid posture switching, breathing frequency adjustment, body temperature regulation, aerosol concentration monitoring, and sampling process, and ensure the accuracy and real-time nature of the evaluation process.

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